Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
Upregulated in class | absentNotch |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | -0.6139088 |
Normalized Enrichment Score (NES) | -1.8888724 |
Nominal p-value | 0.0 |
FDR q-value | 0.0029730252 |
FWER p-Value | 0.0050 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CARM1 | 7040292 | 348 | 3.070 | -0.0029 | No | ||
2 | OTUB1 | 610551 | 928 | 2.097 | -0.0234 | No | ||
3 | FBS1 | 2570520 | 942 | 2.080 | -0.0133 | No | ||
4 | CRSP7 | 4230408 | 1014 | 2.007 | -0.0067 | No | ||
5 | CHKB | 770129 | 1090 | 1.927 | -0.0007 | No | ||
6 | VAMP2 | 2100100 | 1175 | 1.856 | 0.0044 | No | ||
7 | IRF7 | 1570605 | 1280 | 1.754 | 0.0079 | No | ||
8 | E2F6 | 3120133 3850332 4070324 | 1311 | 1.729 | 0.0153 | No | ||
9 | SNRP70 | 4200181 | 1742 | 1.416 | -0.0007 | No | ||
10 | UBE2Q1 | 610348 2350114 4210717 | 1799 | 1.355 | 0.0033 | No | ||
11 | EFNA3 | 6370390 | 1995 | 1.210 | -0.0009 | No | ||
12 | BAZ2A | 730184 | 2418 | 0.958 | -0.0189 | No | ||
13 | ATP5A1 | 1990722 | 2458 | 0.938 | -0.0161 | No | ||
14 | MAST1 | 6940215 | 2557 | 0.872 | -0.0169 | No | ||
15 | TMEM16D | 2650324 | 2664 | 0.819 | -0.0184 | No | ||
16 | PMP22 | 4010239 6550072 | 2853 | 0.715 | -0.0249 | No | ||
17 | USP21 | 3060446 | 2896 | 0.693 | -0.0235 | No | ||
18 | SH2D3C | 3060014 | 3137 | 0.597 | -0.0335 | No | ||
19 | HNRPA0 | 2680048 | 3219 | 0.567 | -0.0349 | No | ||
20 | DOCK9 | 5080037 | 3334 | 0.527 | -0.0384 | No | ||
21 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 3481 | 0.474 | -0.0438 | No | ||
22 | ATAD2 | 870242 2260687 | 3521 | 0.464 | -0.0435 | No | ||
23 | SPRYD3 | 50403 | 3626 | 0.435 | -0.0469 | No | ||
24 | SIPA1L2 | 4850731 | 3645 | 0.431 | -0.0456 | No | ||
25 | HIC2 | 4010433 | 3701 | 0.418 | -0.0464 | No | ||
26 | ZMYND19 | 1570706 6860551 | 3768 | 0.401 | -0.0479 | No | ||
27 | KPNA4 | 510369 | 3774 | 0.400 | -0.0461 | No | ||
28 | KLF3 | 5130438 | 3869 | 0.379 | -0.0493 | No | ||
29 | GABRG2 | 2350402 4210204 6130279 6550037 | 4039 | 0.345 | -0.0566 | No | ||
30 | UNC5A | 2120528 3060324 | 4055 | 0.342 | -0.0557 | No | ||
31 | CDH2 | 520435 2450451 2760025 6650477 | 4395 | 0.285 | -0.0726 | No | ||
32 | AXIN1 | 3360358 6940451 | 4441 | 0.277 | -0.0736 | No | ||
33 | RNF38 | 1940746 3140133 3840601 | 4472 | 0.272 | -0.0738 | No | ||
34 | TBC1D4 | 6420397 | 4566 | 0.258 | -0.0775 | No | ||
35 | SDC2 | 1980168 | 4589 | 0.255 | -0.0774 | No | ||
36 | HIVEP2 | 6520538 | 4671 | 0.244 | -0.0805 | No | ||
37 | SPEN | 2060041 | 4697 | 0.241 | -0.0806 | No | ||
38 | SALL1 | 5420020 7050195 | 4713 | 0.239 | -0.0802 | No | ||
39 | RPS6KA5 | 2120563 7040546 | 4718 | 0.239 | -0.0792 | No | ||
40 | PPP2R5C | 3310121 6650672 | 4724 | 0.238 | -0.0782 | No | ||
41 | PBX3 | 1300424 3710577 6180575 | 4738 | 0.236 | -0.0777 | No | ||
42 | SNAI1 | 6590253 | 4830 | 0.228 | -0.0814 | No | ||
43 | SPRED2 | 510138 540195 | 5050 | 0.201 | -0.0923 | No | ||
44 | FGF13 | 630575 1570440 5360121 | 5333 | 0.172 | -0.1067 | No | ||
45 | WNT5A | 840685 3120152 | 5340 | 0.171 | -0.1062 | No | ||
46 | HS3ST3B1 | 380040 | 5372 | 0.169 | -0.1070 | No | ||
47 | COBLL1 | 4230056 6370494 | 5378 | 0.168 | -0.1064 | No | ||
48 | EPHA7 | 1190288 4010278 | 5394 | 0.167 | -0.1063 | No | ||
49 | SORCS3 | 5700309 | 5395 | 0.167 | -0.1054 | No | ||
50 | ENAH | 1690292 5700300 | 5512 | 0.158 | -0.1109 | No | ||
51 | GAD1 | 2360035 3140167 | 5579 | 0.153 | -0.1137 | No | ||
52 | SPAG8 | 4280446 | 5609 | 0.152 | -0.1145 | No | ||
53 | CRSP6 | 2940358 | 5637 | 0.150 | -0.1152 | No | ||
54 | AR | 6380167 | 5708 | 0.144 | -0.1182 | No | ||
55 | SEMA4C | 1980315 | 5840 | 0.135 | -0.1246 | No | ||
56 | KIF1B | 1240494 2370139 4570270 6510102 | 5966 | 0.126 | -0.1308 | No | ||
57 | FHOD3 | 1240541 | 5986 | 0.124 | -0.1312 | No | ||
58 | PCGF2 | 6370347 | 6086 | 0.119 | -0.1359 | No | ||
59 | NDST1 | 1500427 5340121 | 6091 | 0.119 | -0.1355 | No | ||
60 | VPS13D | 2350451 | 6115 | 0.118 | -0.1361 | No | ||
61 | TTN | 2320161 4670056 6550026 | 6492 | 0.098 | -0.1561 | No | ||
62 | TRAM2 | 3940112 | 6497 | 0.098 | -0.1558 | No | ||
63 | FZD4 | 1580520 | 6611 | 0.093 | -0.1614 | No | ||
64 | PDGFC | 4200133 | 6648 | 0.091 | -0.1629 | No | ||
65 | UNC50 | 4920037 | 6778 | 0.086 | -0.1695 | No | ||
66 | NXPH1 | 3870546 | 6979 | 0.078 | -0.1800 | No | ||
67 | SV2B | 3850717 | 6982 | 0.078 | -0.1797 | No | ||
68 | BASP1 | 5700044 | 7005 | 0.077 | -0.1804 | No | ||
69 | AK5 | 6290348 | 7017 | 0.077 | -0.1806 | No | ||
70 | POU4F1 | 2260315 | 7281 | 0.069 | -0.1946 | No | ||
71 | ZIC1 | 670113 | 7333 | 0.067 | -0.1970 | No | ||
72 | DKK2 | 3610433 | 7393 | 0.065 | -0.1999 | No | ||
73 | TMEFF1 | 2680100 | 7521 | 0.061 | -0.2065 | No | ||
74 | LRRTM3 | 4210021 | 7581 | 0.060 | -0.2093 | No | ||
75 | CDH11 | 1230133 2100180 4610110 | 7772 | 0.055 | -0.2194 | No | ||
76 | EIF2C1 | 6900551 | 8005 | 0.050 | -0.2317 | No | ||
77 | AFF3 | 3870102 | 8092 | 0.048 | -0.2362 | No | ||
78 | GABRA1 | 130372 | 8173 | 0.046 | -0.2403 | No | ||
79 | IL1A | 3610056 | 8204 | 0.045 | -0.2417 | No | ||
80 | BHLHB3 | 3450438 | 8505 | 0.039 | -0.2578 | No | ||
81 | PIK3R1 | 4730671 | 8679 | 0.035 | -0.2670 | No | ||
82 | WDFY3 | 3610041 4560333 4570273 | 8747 | 0.034 | -0.2705 | No | ||
83 | EYA1 | 1450278 5220390 | 8781 | 0.033 | -0.2721 | No | ||
84 | GPC4 | 5910408 | 8875 | 0.031 | -0.2770 | No | ||
85 | UBE2V2 | 4210484 | 8896 | 0.031 | -0.2779 | No | ||
86 | SS18 | 1940440 2900072 6900129 | 8987 | 0.029 | -0.2826 | No | ||
87 | NRXN3 | 1400546 3360471 | 8996 | 0.029 | -0.2829 | No | ||
88 | FOXO1A | 3120670 | 9179 | 0.025 | -0.2927 | No | ||
89 | ZBTB11 | 6520092 | 9239 | 0.024 | -0.2958 | No | ||
90 | SLC25A26 | 4210577 | 9259 | 0.024 | -0.2967 | No | ||
91 | SRPX | 580717 1980162 | 9303 | 0.023 | -0.2989 | No | ||
92 | CPNE8 | 7040039 | 9374 | 0.022 | -0.3026 | No | ||
93 | DACH1 | 2450593 5700592 | 9455 | 0.020 | -0.3068 | No | ||
94 | RALGPS1 | 3440129 6400746 | 9546 | 0.019 | -0.3116 | No | ||
95 | SPIRE2 | 450088 | 9624 | 0.017 | -0.3157 | No | ||
96 | PSD2 | 2060091 | 9939 | 0.012 | -0.3327 | No | ||
97 | NAB1 | 430739 1230114 3390736 6660056 | 10501 | 0.003 | -0.3632 | No | ||
98 | SP4 | 3850176 | 10522 | 0.002 | -0.3643 | No | ||
99 | ZIC2 | 1410408 | 10560 | 0.002 | -0.3663 | No | ||
100 | PUM2 | 4200441 5910446 | 10923 | -0.004 | -0.3859 | No | ||
101 | SERTAD2 | 2810673 6840450 | 10958 | -0.005 | -0.3878 | No | ||
102 | OSBPL6 | 3800072 | 11086 | -0.007 | -0.3946 | No | ||
103 | ADAM10 | 3780156 | 11270 | -0.010 | -0.4045 | No | ||
104 | TLE4 | 1450064 1500519 | 11293 | -0.010 | -0.4057 | No | ||
105 | PDZRN3 | 2340131 | 11353 | -0.012 | -0.4088 | No | ||
106 | PFN2 | 730040 5700026 | 11442 | -0.014 | -0.4135 | No | ||
107 | NLGN1 | 5670278 | 11629 | -0.017 | -0.4235 | No | ||
108 | GRM5 | 60528 | 11708 | -0.018 | -0.4277 | No | ||
109 | CUL5 | 450142 | 11750 | -0.019 | -0.4298 | No | ||
110 | KCNIP4 | 4120435 7050605 | 11873 | -0.022 | -0.4363 | No | ||
111 | RPE | 940114 | 11897 | -0.022 | -0.4375 | No | ||
112 | PCDH18 | 430010 | 12054 | -0.026 | -0.4458 | No | ||
113 | CCNT2 | 2100390 4150563 | 12267 | -0.030 | -0.4572 | No | ||
114 | DLL1 | 1770377 | 12441 | -0.035 | -0.4664 | No | ||
115 | IRX3 | 4200112 | 12472 | -0.036 | -0.4679 | No | ||
116 | BHLHB5 | 6510520 | 12486 | -0.036 | -0.4684 | No | ||
117 | JPH1 | 610739 | 12535 | -0.037 | -0.4708 | No | ||
118 | OVOL1 | 1690131 | 12538 | -0.037 | -0.4707 | No | ||
119 | ARHGAP5 | 2510619 3360035 | 12579 | -0.038 | -0.4727 | No | ||
120 | KCNMA1 | 1450402 | 12701 | -0.042 | -0.4790 | No | ||
121 | FIGN | 7000601 | 12727 | -0.042 | -0.4802 | No | ||
122 | BCOR | 1660452 3940053 | 12768 | -0.044 | -0.4821 | No | ||
123 | MEF2C | 670025 780338 | 12795 | -0.044 | -0.4833 | No | ||
124 | SNX9 | 3290592 | 12945 | -0.049 | -0.4911 | No | ||
125 | ESRRG | 4010181 | 12968 | -0.050 | -0.4921 | No | ||
126 | RSBN1 | 7000487 | 12999 | -0.051 | -0.4934 | No | ||
127 | SP3 | 3840338 | 13400 | -0.066 | -0.5148 | No | ||
128 | SOX21 | 1050110 4670041 6660338 | 13593 | -0.075 | -0.5249 | No | ||
129 | JUN | 840170 | 13623 | -0.077 | -0.5261 | No | ||
130 | GABRA5 | 5570215 | 13714 | -0.083 | -0.5305 | No | ||
131 | UBE3A | 1240152 2690438 5860609 | 13746 | -0.084 | -0.5318 | No | ||
132 | TJP1 | 6350184 | 13748 | -0.084 | -0.5314 | No | ||
133 | PTPN12 | 2030309 6020725 6130746 6290609 | 13765 | -0.085 | -0.5318 | No | ||
134 | RIMS3 | 3890563 | 13885 | -0.094 | -0.5378 | No | ||
135 | MARK1 | 450484 | 14055 | -0.108 | -0.5464 | No | ||
136 | CSNK1A1 | 2340427 | 14138 | -0.115 | -0.5503 | No | ||
137 | NLGN3 | 2650463 | 14223 | -0.124 | -0.5542 | No | ||
138 | THRAP1 | 2470121 | 14284 | -0.131 | -0.5568 | No | ||
139 | SSH2 | 360056 | 14301 | -0.133 | -0.5569 | No | ||
140 | PIP5K3 | 5360112 | 14309 | -0.134 | -0.5566 | No | ||
141 | DUSP16 | 2370082 2480450 | 14532 | -0.163 | -0.5678 | No | ||
142 | TNFSF11 | 6350204 | 14705 | -0.196 | -0.5762 | No | ||
143 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 14783 | -0.211 | -0.5792 | No | ||
144 | XPO7 | 2630215 6760014 | 14877 | -0.230 | -0.5831 | No | ||
145 | GTF2IRD1 | 2030154 3990040 5080372 | 14887 | -0.232 | -0.5824 | No | ||
146 | CDH13 | 5130368 5340114 | 15014 | -0.264 | -0.5878 | No | ||
147 | TRPS1 | 870100 | 15205 | -0.324 | -0.5965 | No | ||
148 | PDE4D | 2470528 6660014 | 15290 | -0.349 | -0.5992 | No | ||
149 | DCUN1D1 | 2360332 | 15362 | -0.375 | -0.6011 | No | ||
150 | CITED2 | 5670114 5130088 | 15380 | -0.379 | -0.6001 | No | ||
151 | PPP2R5D | 4010156 380408 5550112 5670162 | 15506 | -0.422 | -0.6047 | No | ||
152 | PPP1R10 | 110136 3170725 3610484 | 15533 | -0.430 | -0.6038 | No | ||
153 | ARFGEF1 | 6760494 | 15585 | -0.452 | -0.6043 | No | ||
154 | CAPN3 | 1980451 6940047 | 15666 | -0.479 | -0.6061 | No | ||
155 | THRAP2 | 4920600 | 15773 | -0.524 | -0.6091 | Yes | ||
156 | TTC7B | 4760725 | 15800 | -0.533 | -0.6078 | Yes | ||
157 | GAB1 | 2970156 | 15831 | -0.546 | -0.6065 | Yes | ||
158 | ANKRD17 | 2120402 3850035 6400044 | 15875 | -0.565 | -0.6059 | Yes | ||
159 | MADD | 6100725 7000088 | 15877 | -0.566 | -0.6030 | Yes | ||
160 | MLLT10 | 1410288 3290142 | 15899 | -0.577 | -0.6012 | Yes | ||
161 | MBNL2 | 3450707 | 15937 | -0.596 | -0.6001 | Yes | ||
162 | RBBP6 | 2320129 | 15969 | -0.613 | -0.5986 | Yes | ||
163 | LRIG1 | 1050136 | 16231 | -0.750 | -0.6088 | Yes | ||
164 | HIPK1 | 110193 | 16303 | -0.786 | -0.6086 | Yes | ||
165 | RBM12 | 4570239 6040411 6660129 | 16313 | -0.794 | -0.6049 | Yes | ||
166 | CLASP1 | 6860279 | 16434 | -0.859 | -0.6070 | Yes | ||
167 | CDC14A | 4050132 | 16473 | -0.881 | -0.6045 | Yes | ||
168 | DAB2IP | 3170064 6200441 | 16585 | -0.949 | -0.6055 | Yes | ||
169 | MAPK1 | 3190193 6200253 | 16740 | -1.029 | -0.6085 | Yes | ||
170 | BCL7A | 4560095 | 16808 | -1.071 | -0.6066 | Yes | ||
171 | VGLL4 | 6860463 | 16861 | -1.106 | -0.6037 | Yes | ||
172 | ITSN2 | 780484 | 16896 | -1.139 | -0.5996 | Yes | ||
173 | EFTUD1 | 5360736 | 16985 | -1.215 | -0.5980 | Yes | ||
174 | HEMGN | 670411 | 16999 | -1.226 | -0.5923 | Yes | ||
175 | PHF12 | 870400 3130687 | 17070 | -1.295 | -0.5894 | Yes | ||
176 | DNAJC13 | 4730091 | 17096 | -1.317 | -0.5838 | Yes | ||
177 | ANTXR1 | 1990593 2850056 | 17127 | -1.356 | -0.5784 | Yes | ||
178 | ANKRD50 | 870543 | 17130 | -1.358 | -0.5714 | Yes | ||
179 | PHF2 | 4060300 | 17233 | -1.466 | -0.5693 | Yes | ||
180 | IRF2 | 5390044 | 17241 | -1.474 | -0.5620 | Yes | ||
181 | CUGBP2 | 6180121 6840139 | 17288 | -1.521 | -0.5566 | Yes | ||
182 | CDC73 | 1580132 | 17410 | -1.661 | -0.5545 | Yes | ||
183 | FBXO33 | 1510504 | 17453 | -1.704 | -0.5479 | Yes | ||
184 | UTX | 2900017 6770452 | 17486 | -1.741 | -0.5405 | Yes | ||
185 | JARID1B | 4730494 | 17590 | -1.860 | -0.5364 | Yes | ||
186 | ATP2A2 | 1090075 3990279 | 17677 | -1.987 | -0.5307 | Yes | ||
187 | LRP12 | 2370112 | 17784 | -2.131 | -0.5254 | Yes | ||
188 | PDPK1 | 6650168 | 17801 | -2.154 | -0.5150 | Yes | ||
189 | BTG1 | 4200735 6040131 6200133 | 17833 | -2.195 | -0.5053 | Yes | ||
190 | ZFX | 5900400 | 17836 | -2.197 | -0.4939 | Yes | ||
191 | ARID1A | 2630022 1690551 4810110 | 17864 | -2.236 | -0.4837 | Yes | ||
192 | GNB1 | 2120397 | 17866 | -2.237 | -0.4721 | Yes | ||
193 | SFRS3 | 770315 4230593 | 17869 | -2.240 | -0.4605 | Yes | ||
194 | EIF4ENIF1 | 2060341 | 17897 | -2.292 | -0.4500 | Yes | ||
195 | NCOA1 | 3610438 | 17979 | -2.418 | -0.4418 | Yes | ||
196 | ETF1 | 6770075 | 17996 | -2.447 | -0.4299 | Yes | ||
197 | DHX36 | 2470465 | 18044 | -2.528 | -0.4193 | Yes | ||
198 | PAIP1 | 3870576 | 18053 | -2.557 | -0.4064 | Yes | ||
199 | HMGCS1 | 6620452 | 18065 | -2.584 | -0.3935 | Yes | ||
200 | CREBBP | 5690035 7040050 | 18081 | -2.625 | -0.3806 | Yes | ||
201 | MTPN | 3940167 | 18101 | -2.686 | -0.3676 | Yes | ||
202 | RYBP | 60746 | 18116 | -2.714 | -0.3542 | Yes | ||
203 | DDX3X | 2190020 | 18122 | -2.725 | -0.3403 | Yes | ||
204 | NMT1 | 5810152 | 18157 | -2.796 | -0.3275 | Yes | ||
205 | CTDSPL | 4670546 | 18227 | -2.969 | -0.3158 | Yes | ||
206 | TBK1 | 5690338 | 18325 | -3.258 | -0.3041 | Yes | ||
207 | PIAS1 | 5340301 | 18332 | -3.281 | -0.2873 | Yes | ||
208 | CLPX | 6220156 | 18336 | -3.290 | -0.2703 | Yes | ||
209 | ITGB1 | 5080156 6270528 | 18356 | -3.381 | -0.2537 | Yes | ||
210 | FMNL2 | 4060438 | 18376 | -3.452 | -0.2367 | Yes | ||
211 | NUDT4 | 6760689 | 18388 | -3.497 | -0.2191 | Yes | ||
212 | KBTBD2 | 2320014 | 18404 | -3.580 | -0.2012 | Yes | ||
213 | BRD7 | 2120068 6200746 | 18475 | -3.892 | -0.1847 | Yes | ||
214 | APLP2 | 3610037 | 18519 | -4.170 | -0.1653 | Yes | ||
215 | PPP3CB | 6020156 | 18527 | -4.258 | -0.1434 | Yes | ||
216 | SRPK2 | 6380341 | 18529 | -4.282 | -0.1212 | Yes | ||
217 | SIN3A | 2190121 | 18531 | -4.292 | -0.0988 | Yes | ||
218 | UBE2G1 | 2230546 5420528 7040463 | 18536 | -4.350 | -0.0763 | Yes | ||
219 | AP3S1 | 5570044 | 18568 | -4.776 | -0.0531 | Yes | ||
220 | RHOT1 | 6760692 | 18580 | -4.864 | -0.0283 | Yes | ||
221 | MCL1 | 1660672 | 18604 | -5.794 | 0.0007 | Yes |