Details for gene set DNA_DAMAGE_RESPONSE__SIGNAL_TRANSDUCTION_RESULTING_IN_INDUCTION_OF

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos
Phenotype	phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos
Upregulated in class	wtNotch
GeneSet	DNA_DAMAGE_RESPONSE__SIGNAL_TRANSDUCTION_RESULTING_IN_INDUCTION_OF_APOPTOSIS
Enrichment Score (ES)	-0.7580231
Normalized Enrichment Score (NES)	-1.456254
Nominal p-value	0.042194095
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: DNA_DAMAGE_RESPONSE__SIGNAL_TRANSDUCTION_RESULTING_IN_INDUCTION_OF_APOPTOSIS
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	SFN	6290301 7510608	3809	0.174	-0.1629	No
2	BRCA1	4780669	5285	0.081	-0.2226	No
3	CIDEA	4560020	7819	0.022	-0.3534	No
4	CHEK2	610139 1050022	8372	0.014	-0.3797	No
5	IFI16	6520601	8901	0.006	-0.4066	No
6	CIDEB	3360274	9852	-0.006	-0.4561	No
7	AIFM1	2060070 5890086	10369	-0.014	-0.4804	No
8	PML	50093 2190435 2450402 3840082	10965	-0.024	-0.5067	No
9	PCBP4	6350722	15431	-0.255	-0.6854	Yes
10	ABL1	1050593 2030050 4010114	16784	-0.585	-0.6176	Yes
11	TP53	6130707	18184	-1.390	-0.3590	Yes
12	BCL3	3990440	18315	-1.592	0.0162	Yes

Fig 2: DNA_DAMAGE_RESPONSE__SIGNAL_TRANSDUCTION_RESULTING_IN_INDUCTION_OF_APOPTOSIS
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: DNA_DAMAGE_RESPONSE__SIGNAL_TRANSDUCTION_RESULTING_IN_INDUCTION_OF_APOPTOSIS: Random ES distribution
Gene set null distribution of ES for DNA_DAMAGE_RESPONSE__SIGNAL_TRANSDUCTION_RESULTING_IN_INDUCTION_OF_APOPTOSIS