Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | LAL_KO_3MO_UP |
| Enrichment Score (ES) | 0.6932735 |
| Normalized Enrichment Score (NES) | 1.705417 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.11290413 |
| FWER p-Value | 0.565 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SLC40A1 | 2370286 | 5 | 3.698 | 0.1754 | Yes | ||
| 2 | HMOX1 | 1740687 | 142 | 2.093 | 0.2675 | Yes | ||
| 3 | NEU1 | 380546 | 256 | 1.780 | 0.3460 | Yes | ||
| 4 | CD68 | 6350450 | 428 | 1.506 | 0.4083 | Yes | ||
| 5 | SLC11A1 | 940286 2810435 6370647 | 492 | 1.413 | 0.4721 | Yes | ||
| 6 | CTSB | 1400524 2360064 | 889 | 1.092 | 0.5026 | Yes | ||
| 7 | S100A9 | 7050528 | 1172 | 0.953 | 0.5327 | Yes | ||
| 8 | TREM2 | 6290358 | 1251 | 0.901 | 0.5713 | Yes | ||
| 9 | MMP12 | 4920070 | 1252 | 0.901 | 0.6141 | Yes | ||
| 10 | LY9 | 3360315 4070292 | 1340 | 0.853 | 0.6499 | Yes | ||
| 11 | CAMP | 6290735 | 1535 | 0.759 | 0.6755 | Yes | ||
| 12 | MARCO | 870056 | 1779 | 0.650 | 0.6933 | Yes | ||
| 13 | UTRN | 3390048 | 3331 | 0.235 | 0.6209 | No | ||
| 14 | RGS1 | 4060347 4540181 | 3385 | 0.228 | 0.6289 | No | ||
| 15 | CLEC4E | 2940102 6550735 | 3995 | 0.159 | 0.6037 | No | ||
| 16 | EMR4 | 7040711 | 4327 | 0.132 | 0.5921 | No | ||
| 17 | CCR1 | 3440672 | 4487 | 0.121 | 0.5893 | No | ||
| 18 | IL1R2 | 1410600 | 4528 | 0.118 | 0.5928 | No | ||
| 19 | IL8RB | 450592 1170537 | 4761 | 0.104 | 0.5853 | No | ||
| 20 | GDF15 | 4730017 | 5056 | 0.091 | 0.5737 | No | ||
| 21 | MS4A7 | 2260465 | 5386 | 0.078 | 0.5597 | No | ||
| 22 | MMP19 | 5080377 | 5895 | 0.062 | 0.5353 | No | ||
| 23 | SNX6 | 6200086 | 8226 | 0.016 | 0.4106 | No | ||
| 24 | FCER1G | 5550020 | 8594 | 0.011 | 0.3914 | No | ||
| 25 | PLA2G7 | 4730092 | 8665 | 0.010 | 0.3881 | No | ||
| 26 | DNMT3A | 4050068 4810717 | 8894 | 0.006 | 0.3761 | No | ||
| 27 | SEMA7A | 2630239 5050593 | 9388 | -0.000 | 0.3496 | No | ||
| 28 | CD5L | 4070605 | 11056 | -0.025 | 0.2610 | No | ||
| 29 | FABP7 | 4590142 | 11231 | -0.028 | 0.2530 | No | ||
| 30 | MAFB | 1230471 | 11291 | -0.029 | 0.2511 | No | ||
| 31 | SPIC | 2060017 | 12432 | -0.053 | 0.1923 | No | ||
| 32 | MSR1 | 940538 | 12681 | -0.060 | 0.1818 | No | ||
| 33 | SLC15A3 | 6650333 | 12960 | -0.069 | 0.1701 | No | ||
| 34 | TLR7 | 3140300 | 13042 | -0.072 | 0.1691 | No | ||
| 35 | MMP8 | 7100064 | 13445 | -0.088 | 0.1516 | No | ||
| 36 | IGSF6 | 5340348 | 14006 | -0.116 | 0.1270 | No | ||
| 37 | SAA2 | 1090139 | 14373 | -0.140 | 0.1140 | No | ||
| 38 | MYO5A | 2900288 5270333 | 14680 | -0.167 | 0.1054 | No | ||
| 39 | APOBEC1 | 4610022 | 14961 | -0.194 | 0.0995 | No | ||
| 40 | TNFAIP2 | 70438 1740215 | 15001 | -0.197 | 0.1068 | No | ||
| 41 | GPNMB | 1780138 2340176 3390403 4560156 | 15185 | -0.221 | 0.1074 | No | ||
| 42 | FKBP5 | 2190048 | 16035 | -0.368 | 0.0792 | No | ||
| 43 | ACP5 | 2230717 | 18060 | -1.257 | 0.0299 | No |
