Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY |
| Enrichment Score (ES) | 0.6041707 |
| Normalized Enrichment Score (NES) | 1.5232989 |
| Nominal p-value | 0.009153318 |
| FDR q-value | 0.58909404 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SMAD4 | 5670519 | 72 | 4.465 | 0.1565 | Yes | ||
| 2 | SMAD5 | 5700497 | 148 | 3.849 | 0.2907 | Yes | ||
| 3 | MAP3K7 | 6040068 | 670 | 2.361 | 0.3475 | Yes | ||
| 4 | SMAD2 | 4200592 | 912 | 2.023 | 0.4072 | Yes | ||
| 5 | CDKN1C | 6520577 | 996 | 1.891 | 0.4706 | Yes | ||
| 6 | FNTA | 70059 | 1075 | 1.808 | 0.5314 | Yes | ||
| 7 | ACVR2B | 1660546 | 1097 | 1.780 | 0.5942 | Yes | ||
| 8 | EID2 | 3130176 | 1734 | 1.128 | 0.6005 | Yes | ||
| 9 | LEFTY1 | 3290452 | 2223 | 0.835 | 0.6042 | Yes | ||
| 10 | ACVR1B | 3610446 5570195 | 2980 | 0.471 | 0.5804 | No | ||
| 11 | CITED2 | 5670114 5130088 | 3236 | 0.379 | 0.5803 | No | ||
| 12 | BMPR1A | 2190193 4060603 | 3376 | 0.335 | 0.5848 | No | ||
| 13 | SMURF1 | 520609 580647 | 3380 | 0.334 | 0.5966 | No | ||
| 14 | GDF9 | 2350181 | 3528 | 0.287 | 0.5990 | No | ||
| 15 | ZFYVE9 | 6980288 7100017 | 3637 | 0.254 | 0.6024 | No | ||
| 16 | CDKN2B | 6020040 | 4239 | 0.141 | 0.5751 | No | ||
| 17 | ACVR1 | 6840671 | 4475 | 0.115 | 0.5666 | No | ||
| 18 | RGMB | 670504 4570450 | 4838 | 0.087 | 0.5502 | No | ||
| 19 | TGFBR3 | 5290577 | 5923 | 0.042 | 0.4933 | No | ||
| 20 | GDF5 | 510440 | 5964 | 0.041 | 0.4926 | No | ||
| 21 | LEFTY2 | 5670364 | 6046 | 0.038 | 0.4896 | No | ||
| 22 | FMOD | 540577 | 6663 | 0.024 | 0.4573 | No | ||
| 23 | KLF10 | 4850056 | 7935 | 0.000 | 0.3889 | No | ||
| 24 | GDF10 | 4850082 | 7989 | -0.001 | 0.3861 | No | ||
| 25 | LTBP2 | 4850039 | 9026 | -0.018 | 0.3309 | No | ||
| 26 | TGFBR1 | 1400148 4280020 6550711 | 9267 | -0.022 | 0.3188 | No | ||
| 27 | SMAD7 | 430377 | 9316 | -0.023 | 0.3171 | No | ||
| 28 | ACVR2A | 6110647 | 10239 | -0.042 | 0.2689 | No | ||
| 29 | IL17F | 670577 | 10364 | -0.044 | 0.2638 | No | ||
| 30 | FOXH1 | 2060180 | 10529 | -0.048 | 0.2567 | No | ||
| 31 | SOST | 1170195 | 11186 | -0.064 | 0.2237 | No | ||
| 32 | SMAD1 | 630537 1850333 | 11401 | -0.071 | 0.2147 | No | ||
| 33 | HIPK2 | 6350647 | 11501 | -0.074 | 0.2121 | No | ||
| 34 | GDF15 | 4730017 | 11732 | -0.082 | 0.2026 | No | ||
| 35 | ACVRL1 | 3290600 | 11941 | -0.090 | 0.1947 | No | ||
| 36 | CIDEA | 4560020 | 12816 | -0.137 | 0.1525 | No | ||
| 37 | SNX6 | 6200086 | 13259 | -0.170 | 0.1348 | No | ||
| 38 | ENG | 4280270 | 13420 | -0.183 | 0.1328 | No | ||
| 39 | HPGD | 6770192 | 13876 | -0.236 | 0.1168 | No | ||
| 40 | BMPR2 | 5340066 6960328 | 14463 | -0.324 | 0.0969 | No | ||
| 41 | TGFB1 | 1940162 | 15204 | -0.500 | 0.0750 | No | ||
| 42 | STUB1 | 5860086 | 16689 | -1.258 | 0.0403 | No | ||
| 43 | SMAD3 | 6450671 | 17349 | -1.764 | 0.0682 | No |
