Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$SRF_C |
Enrichment Score (ES) | -0.4430443 |
Normalized Enrichment Score (NES) | -1.281766 |
Nominal p-value | 0.030508475 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RRM1 | 4150433 | 712 | 2.297 | -0.0145 | No | ||
2 | AKAP12 | 1450739 | 845 | 2.116 | 0.0005 | No | ||
3 | VCL | 4120487 | 901 | 2.044 | 0.0189 | No | ||
4 | FOXP1 | 6510433 | 1060 | 1.822 | 0.0294 | No | ||
5 | MAPK14 | 5290731 | 1140 | 1.736 | 0.0433 | No | ||
6 | RBBP7 | 430113 450450 2370309 | 1507 | 1.334 | 0.0375 | No | ||
7 | HOXB4 | 540131 | 1545 | 1.296 | 0.0490 | No | ||
8 | PHF12 | 870400 3130687 | 1546 | 1.295 | 0.0626 | No | ||
9 | YWHAZ | 1230717 | 1558 | 1.283 | 0.0754 | No | ||
10 | MBNL1 | 2640762 7100048 | 1576 | 1.263 | 0.0877 | No | ||
11 | GADD45G | 2510142 | 1766 | 1.097 | 0.0890 | No | ||
12 | SLC25A4 | 2360519 | 1971 | 0.981 | 0.0882 | No | ||
13 | CDC14A | 4050132 | 2143 | 0.881 | 0.0882 | No | ||
14 | PPP1R12A | 4070066 4590162 | 2393 | 0.748 | 0.0825 | No | ||
15 | BCAS3 | 4050647 | 2481 | 0.687 | 0.0850 | No | ||
16 | MCAM | 5130270 6620577 | 2597 | 0.635 | 0.0854 | No | ||
17 | EGR2 | 3800403 | 3028 | 0.452 | 0.0669 | No | ||
18 | SCOC | 610048 2230053 | 3099 | 0.427 | 0.0675 | No | ||
19 | KCTD15 | 2810735 | 3191 | 0.395 | 0.0667 | No | ||
20 | EML4 | 5700373 | 3202 | 0.390 | 0.0703 | No | ||
21 | ELAVL4 | 50735 3360086 5220167 | 3310 | 0.352 | 0.0682 | No | ||
22 | ROCK2 | 1780035 5720025 | 3498 | 0.295 | 0.0611 | No | ||
23 | SPAG7 | 4560524 | 3517 | 0.290 | 0.0632 | No | ||
24 | AOC3 | 6840129 | 3596 | 0.266 | 0.0618 | No | ||
25 | EGR4 | 3120750 | 3703 | 0.239 | 0.0585 | No | ||
26 | KRTCAP2 | 5220040 | 3708 | 0.238 | 0.0608 | No | ||
27 | LTBP1 | 780035 2100746 2760402 3780551 6550184 6860193 | 3722 | 0.234 | 0.0625 | No | ||
28 | RASD2 | 3360010 | 3793 | 0.218 | 0.0610 | No | ||
29 | PFN1 | 6130132 | 3881 | 0.201 | 0.0584 | No | ||
30 | FGFRL1 | 6370047 | 3907 | 0.197 | 0.0591 | No | ||
31 | ERBB2IP | 580253 1090672 | 3909 | 0.196 | 0.0611 | No | ||
32 | ABL1 | 1050593 2030050 4010114 | 3953 | 0.186 | 0.0608 | No | ||
33 | DUSP6 | 5910286 7100070 | 4043 | 0.170 | 0.0577 | No | ||
34 | PRKAB2 | 6980300 | 4059 | 0.167 | 0.0587 | No | ||
35 | DNAJB4 | 380195 2760372 3940735 | 4133 | 0.157 | 0.0563 | No | ||
36 | SLC7A1 | 2450193 2710241 | 4280 | 0.137 | 0.0499 | No | ||
37 | STARD13 | 540722 | 4364 | 0.128 | 0.0467 | No | ||
38 | MYL7 | 2480541 | 4388 | 0.124 | 0.0468 | No | ||
39 | ITGA7 | 1230739 | 4433 | 0.120 | 0.0456 | No | ||
40 | MYLK | 4010600 7000364 | 4454 | 0.118 | 0.0458 | No | ||
41 | ACVR1 | 6840671 | 4475 | 0.115 | 0.0459 | No | ||
42 | COL1A2 | 380364 | 4635 | 0.102 | 0.0384 | No | ||
43 | ITGB6 | 2810068 4570332 | 4735 | 0.094 | 0.0340 | No | ||
44 | COL8A1 | 4590050 | 4806 | 0.089 | 0.0311 | No | ||
45 | ITGB1BP2 | 6200129 | 5009 | 0.076 | 0.0210 | No | ||
46 | TANK | 1090020 2060458 2370400 | 5015 | 0.076 | 0.0215 | No | ||
47 | GPR20 | 6620601 | 5179 | 0.067 | 0.0134 | No | ||
48 | MYO1E | 3140504 | 5208 | 0.066 | 0.0126 | No | ||
49 | LMCD1 | 1740484 2190097 | 5317 | 0.062 | 0.0073 | No | ||
50 | LIN28 | 6590672 | 5515 | 0.054 | -0.0028 | No | ||
51 | IL17B | 6940711 | 5528 | 0.054 | -0.0028 | No | ||
52 | ACTR3 | 1400497 | 5594 | 0.052 | -0.0058 | No | ||
53 | CACNA1B | 1740010 5360593 | 5675 | 0.049 | -0.0096 | No | ||
54 | SLC2A4 | 540441 | 5797 | 0.045 | -0.0157 | No | ||
55 | SYNCRIP | 1690195 3140113 4670279 | 6115 | 0.036 | -0.0325 | No | ||
56 | DLL1 | 1770377 | 6175 | 0.035 | -0.0353 | No | ||
57 | ACTB | 1660736 2030204 2060215 5050047 | 6268 | 0.032 | -0.0400 | No | ||
58 | MYH11 | 7100273 | 6362 | 0.030 | -0.0447 | No | ||
59 | FOSB | 1940142 | 6364 | 0.030 | -0.0444 | No | ||
60 | MITF | 380056 | 6523 | 0.026 | -0.0527 | No | ||
61 | MYL9 | 4210750 7050138 | 6857 | 0.019 | -0.0706 | No | ||
62 | PLN | 3940132 | 7360 | 0.010 | -0.0977 | No | ||
63 | MEIS1 | 1400575 | 7380 | 0.010 | -0.0986 | No | ||
64 | CFL2 | 380239 6200368 | 7413 | 0.009 | -0.1002 | No | ||
65 | DSTN | 3140592 | 7472 | 0.008 | -0.1033 | No | ||
66 | CRK | 1230162 4780128 | 7694 | 0.004 | -0.1152 | No | ||
67 | NR2F2 | 3170609 3310577 | 8001 | -0.001 | -0.1318 | No | ||
68 | POPDC2 | 2030056 | 8026 | -0.001 | -0.1331 | No | ||
69 | HOXD10 | 6100039 | 8455 | -0.009 | -0.1562 | No | ||
70 | TCF2 | 870338 5050632 | 8660 | -0.012 | -0.1671 | No | ||
71 | NKX2-2 | 4150731 | 9365 | -0.024 | -0.2050 | No | ||
72 | KCNK3 | 2690372 | 9382 | -0.024 | -0.2056 | No | ||
73 | ASPA | 3290400 | 9386 | -0.024 | -0.2055 | No | ||
74 | NPAS2 | 770670 | 9849 | -0.033 | -0.2302 | No | ||
75 | LPP | 1660541 | 9890 | -0.034 | -0.2320 | No | ||
76 | TAGLN | 6660280 | 9894 | -0.034 | -0.2318 | No | ||
77 | MYO1B | 770372 | 10173 | -0.041 | -0.2464 | No | ||
78 | NR4A1 | 6290161 | 10270 | -0.042 | -0.2512 | No | ||
79 | HOXA5 | 6840026 | 10312 | -0.043 | -0.2530 | No | ||
80 | FOSL1 | 430021 | 10317 | -0.043 | -0.2527 | No | ||
81 | DIXDC1 | 6980435 | 10381 | -0.045 | -0.2557 | No | ||
82 | DMD | 1740041 3990332 | 10389 | -0.045 | -0.2556 | No | ||
83 | KCNMB1 | 4760139 | 10456 | -0.047 | -0.2587 | No | ||
84 | ACTA1 | 840538 | 11083 | -0.061 | -0.2919 | No | ||
85 | TGFB1I1 | 2060288 6550450 | 11173 | -0.063 | -0.2961 | No | ||
86 | CALD1 | 1770129 1940397 | 11583 | -0.077 | -0.3174 | No | ||
87 | HOXA3 | 3610632 6020358 | 11631 | -0.078 | -0.3192 | No | ||
88 | CNN1 | 510707 | 11727 | -0.082 | -0.3235 | No | ||
89 | GFPT2 | 2370129 | 12032 | -0.094 | -0.3389 | No | ||
90 | CFL1 | 2340735 | 12117 | -0.097 | -0.3425 | No | ||
91 | THBS1 | 4560494 430288 | 12132 | -0.098 | -0.3422 | No | ||
92 | MAP1A | 4920576 | 12429 | -0.114 | -0.3571 | No | ||
93 | HOXB5 | 2900538 | 12437 | -0.114 | -0.3562 | No | ||
94 | CA3 | 870687 5890390 | 12462 | -0.116 | -0.3563 | No | ||
95 | IER2 | 2030008 | 12496 | -0.117 | -0.3569 | No | ||
96 | RASSF2 | 2480079 5720546 | 12625 | -0.124 | -0.3625 | No | ||
97 | SRD5A2 | 6840433 | 12802 | -0.136 | -0.3706 | No | ||
98 | CYR61 | 1240408 5290026 4120452 6550008 | 12825 | -0.138 | -0.3704 | No | ||
99 | GGN | 1410528 4210082 5290170 | 12880 | -0.142 | -0.3718 | No | ||
100 | SSH3 | 6290110 6650497 | 13000 | -0.151 | -0.3767 | No | ||
101 | NR2F1 | 4120528 360402 | 13192 | -0.165 | -0.3853 | No | ||
102 | MYO18B | 7100670 | 13215 | -0.167 | -0.3847 | No | ||
103 | MATR3 | 1940170 5340278 | 13247 | -0.169 | -0.3846 | No | ||
104 | TADA3L | 4210070 5720088 6660333 | 13438 | -0.185 | -0.3930 | No | ||
105 | STAT5B | 6200026 | 13637 | -0.210 | -0.4015 | No | ||
106 | EFHD1 | 4070358 | 13832 | -0.232 | -0.4096 | No | ||
107 | DUSP2 | 2370184 | 13886 | -0.237 | -0.4100 | No | ||
108 | FOS | 1850315 | 13888 | -0.238 | -0.4076 | No | ||
109 | TNNC1 | 1990575 | 14097 | -0.265 | -0.4161 | No | ||
110 | JPH2 | 940041 5860026 | 14143 | -0.272 | -0.4156 | No | ||
111 | NKX6-2 | 2450332 3120333 | 14208 | -0.283 | -0.4161 | No | ||
112 | FOXP2 | 3520561 4150372 4760524 | 14381 | -0.312 | -0.4222 | No | ||
113 | FOXE3 | 6900102 | 14395 | -0.314 | -0.4196 | No | ||
114 | LRP5 | 2100397 3170484 | 14514 | -0.333 | -0.4225 | No | ||
115 | MRGPRF | 4780746 | 14552 | -0.341 | -0.4210 | No | ||
116 | TRIM46 | 3520609 4590010 | 14684 | -0.367 | -0.4242 | No | ||
117 | MRVI1 | 4810338 4850601 5900441 | 14869 | -0.405 | -0.4299 | No | ||
118 | PLCB3 | 4670402 | 15112 | -0.469 | -0.4381 | Yes | ||
119 | TITF1 | 3390554 4540292 | 15131 | -0.473 | -0.4342 | Yes | ||
120 | ACTG2 | 4780180 | 15160 | -0.485 | -0.4306 | Yes | ||
121 | DVL3 | 360156 5390075 | 15245 | -0.515 | -0.4298 | Yes | ||
122 | EGR3 | 6940128 | 15440 | -0.582 | -0.4342 | Yes | ||
123 | CAP1 | 2650278 | 15489 | -0.600 | -0.4305 | Yes | ||
124 | EMILIN2 | 70253 | 15511 | -0.606 | -0.4253 | Yes | ||
125 | PADI2 | 2940092 6420136 | 15515 | -0.607 | -0.4191 | Yes | ||
126 | TPM3 | 670600 3170296 5670167 6650471 | 15740 | -0.702 | -0.4239 | Yes | ||
127 | POU3F4 | 870274 | 15748 | -0.707 | -0.4169 | Yes | ||
128 | ARHGAP1 | 2810010 5270064 | 15902 | -0.793 | -0.4168 | Yes | ||
129 | SRF | 70139 2320039 | 15926 | -0.804 | -0.4097 | Yes | ||
130 | TOP1 | 770471 4060632 6650324 | 15975 | -0.831 | -0.4036 | Yes | ||
131 | PDLIM4 | 3990358 | 16098 | -0.898 | -0.4008 | Yes | ||
132 | RSU1 | 4850372 | 16239 | -0.982 | -0.3981 | Yes | ||
133 | TUFT1 | 540047 2370010 | 16296 | -1.011 | -0.3905 | Yes | ||
134 | USP52 | 3710215 6380133 | 16385 | -1.057 | -0.3842 | Yes | ||
135 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 16462 | -1.101 | -0.3768 | Yes | ||
136 | GRK6 | 1500053 | 16470 | -1.105 | -0.3656 | Yes | ||
137 | RHOJ | 6660176 | 16510 | -1.139 | -0.3558 | Yes | ||
138 | SIPA1 | 5220687 | 17003 | -1.500 | -0.3667 | Yes | ||
139 | FHL2 | 1400008 | 17004 | -1.500 | -0.3510 | Yes | ||
140 | CKM | 1450524 | 17033 | -1.513 | -0.3367 | Yes | ||
141 | ARPC4 | 2900056 | 17124 | -1.577 | -0.3250 | Yes | ||
142 | LCP1 | 4280397 | 17133 | -1.583 | -0.3089 | Yes | ||
143 | MYL6 | 60563 6100152 | 17168 | -1.608 | -0.2939 | Yes | ||
144 | RUNDC1 | 2450037 | 17177 | -1.612 | -0.2775 | Yes | ||
145 | DAPK3 | 4590121 | 17202 | -1.635 | -0.2616 | Yes | ||
146 | ASB2 | 4760168 | 17211 | -1.640 | -0.2449 | Yes | ||
147 | TAZ | 7100193 | 17274 | -1.703 | -0.2304 | Yes | ||
148 | FLNA | 5390193 | 17445 | -1.860 | -0.2201 | Yes | ||
149 | JUNB | 4230048 | 17478 | -1.886 | -0.2021 | Yes | ||
150 | CNN2 | 2230433 5270446 | 17495 | -1.897 | -0.1831 | Yes | ||
151 | EGR1 | 4610347 | 17755 | -2.187 | -0.1743 | Yes | ||
152 | TLE3 | 580040 4730121 | 18007 | -2.546 | -0.1612 | Yes | ||
153 | PDLIM7 | 4780136 | 18123 | -2.731 | -0.1388 | Yes | ||
154 | MUS81 | 6660184 | 18155 | -2.781 | -0.1114 | Yes | ||
155 | DUSP10 | 2850673 3360064 | 18230 | -2.963 | -0.0844 | Yes | ||
156 | PNKP | 4610685 5720605 | 18578 | -4.908 | -0.0518 | Yes | ||
157 | ANXA6 | 2190014 | 18586 | -5.135 | 0.0016 | Yes |