Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$PEA3_Q6 |
Enrichment Score (ES) | -0.45289636 |
Normalized Enrichment Score (NES) | -1.2871361 |
Nominal p-value | 0.023961661 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PRKACB | 4210170 | 9 | 6.062 | 0.0351 | No | ||
2 | CD84 | 1780168 | 273 | 3.329 | 0.0404 | No | ||
3 | TRIM8 | 6130441 | 453 | 2.806 | 0.0471 | No | ||
4 | EXTL2 | 5050433 | 485 | 2.735 | 0.0615 | No | ||
5 | TCEB3 | 5890156 | 689 | 2.336 | 0.0642 | No | ||
6 | MR1 | 3850037 | 692 | 2.331 | 0.0778 | No | ||
7 | VCAM1 | 2900450 | 786 | 2.190 | 0.0856 | No | ||
8 | ZDHHC5 | 1690711 | 876 | 2.080 | 0.0929 | No | ||
9 | CBL | 6380068 | 1079 | 1.799 | 0.0926 | No | ||
10 | SPATA6 | 4590373 | 1126 | 1.749 | 0.1003 | No | ||
11 | LRMP | 6290193 | 1177 | 1.692 | 0.1075 | No | ||
12 | PTPRC | 130402 5290148 | 1282 | 1.574 | 0.1111 | No | ||
13 | FLI1 | 3990142 | 1423 | 1.419 | 0.1119 | No | ||
14 | VDAC2 | 7000215 | 1464 | 1.378 | 0.1178 | No | ||
15 | IL18BP | 3450128 | 1499 | 1.342 | 0.1238 | No | ||
16 | GFI1 | 730180 | 1550 | 1.293 | 0.1287 | No | ||
17 | PUM1 | 6130500 | 1654 | 1.182 | 0.1301 | No | ||
18 | FCGR3A | 3840184 | 1658 | 1.178 | 0.1368 | No | ||
19 | TNFRSF19L | 1170168 1190358 5670270 | 1677 | 1.165 | 0.1427 | No | ||
20 | NT5C2 | 4280735 4670528 | 1707 | 1.148 | 0.1478 | No | ||
21 | CTSS | 1740056 | 1895 | 1.016 | 0.1436 | No | ||
22 | GATA3 | 6130068 | 1948 | 0.991 | 0.1466 | No | ||
23 | LAMC1 | 4730025 | 2095 | 0.908 | 0.1441 | No | ||
24 | INPPL1 | 110717 3120164 | 2119 | 0.893 | 0.1481 | No | ||
25 | CDC14A | 4050132 | 2143 | 0.881 | 0.1520 | No | ||
26 | DCLRE1C | 1450041 2360091 3290671 3390739 | 2203 | 0.844 | 0.1537 | No | ||
27 | HIPK1 | 110193 | 2313 | 0.786 | 0.1524 | No | ||
28 | SEC24C | 6980707 | 2354 | 0.763 | 0.1547 | No | ||
29 | SLC30A7 | 2230463 | 2398 | 0.745 | 0.1568 | No | ||
30 | HHEX | 2340575 | 2457 | 0.703 | 0.1578 | No | ||
31 | ANK3 | 1500161 2900435 4210154 6400100 | 2469 | 0.695 | 0.1613 | No | ||
32 | CMAS | 2190129 | 2480 | 0.688 | 0.1647 | No | ||
33 | TRIM33 | 580619 2230280 3990433 6200747 | 2532 | 0.659 | 0.1658 | No | ||
34 | SORL1 | 630204 | 2838 | 0.526 | 0.1524 | No | ||
35 | RIN1 | 510593 | 2853 | 0.520 | 0.1547 | No | ||
36 | LZTS2 | 2260440 | 2978 | 0.471 | 0.1507 | No | ||
37 | CTBP2 | 430309 3710079 | 3047 | 0.445 | 0.1497 | No | ||
38 | ITPR2 | 5360128 | 3049 | 0.445 | 0.1522 | No | ||
39 | MARK2 | 7210608 | 3106 | 0.424 | 0.1517 | No | ||
40 | CD69 | 380167 4730088 | 3140 | 0.411 | 0.1523 | No | ||
41 | NCAM1 | 3140026 | 3200 | 0.391 | 0.1514 | No | ||
42 | ELAVL4 | 50735 3360086 5220167 | 3310 | 0.352 | 0.1476 | No | ||
43 | PICALM | 1940280 | 3454 | 0.310 | 0.1416 | No | ||
44 | IL18 | 6180039 | 3546 | 0.281 | 0.1384 | No | ||
45 | SLC41A1 | 1230528 | 3655 | 0.251 | 0.1340 | No | ||
46 | RPS3 | 1570017 2370170 | 3843 | 0.209 | 0.1251 | No | ||
47 | FEN1 | 1770541 | 4062 | 0.166 | 0.1142 | No | ||
48 | PAFAH2 | 3140451 5720593 6510014 | 4248 | 0.141 | 0.1050 | No | ||
49 | XCL1 | 3800504 | 4405 | 0.122 | 0.0973 | No | ||
50 | PDGFD | 60438 | 4416 | 0.121 | 0.0975 | No | ||
51 | ABLIM1 | 580170 3710338 6520504 | 4460 | 0.117 | 0.0958 | No | ||
52 | LRFN4 | 5670368 | 4464 | 0.116 | 0.0964 | No | ||
53 | WASF2 | 4850592 | 4480 | 0.115 | 0.0962 | No | ||
54 | MARK1 | 450484 | 4561 | 0.108 | 0.0925 | No | ||
55 | AKT3 | 1580270 3290278 | 4634 | 0.102 | 0.0892 | No | ||
56 | FUT11 | 6040692 | 4843 | 0.086 | 0.0784 | No | ||
57 | IVL | 4560500 | 5429 | 0.057 | 0.0471 | No | ||
58 | VPS11 | 1090048 6040372 | 5461 | 0.056 | 0.0457 | No | ||
59 | LIN28 | 6590672 | 5515 | 0.054 | 0.0432 | No | ||
60 | IRAK4 | 5390156 6130594 | 5693 | 0.049 | 0.0339 | No | ||
61 | ELK4 | 460494 940369 4480136 | 6301 | 0.032 | 0.0012 | No | ||
62 | GRIN2B | 3800333 | 6303 | 0.032 | 0.0013 | No | ||
63 | CAPZA1 | 3140390 | 6655 | 0.024 | -0.0176 | No | ||
64 | XPNPEP1 | 2640750 3850315 6200242 | 7204 | 0.013 | -0.0472 | No | ||
65 | SPRR4 | 5720273 | 7270 | 0.011 | -0.0506 | No | ||
66 | GPA33 | 2650044 | 8668 | -0.012 | -0.1262 | No | ||
67 | RNASEL | 2340133 | 8861 | -0.015 | -0.1366 | No | ||
68 | CPNE8 | 7040039 | 9242 | -0.022 | -0.1570 | No | ||
69 | LALBA | 6940685 | 9446 | -0.025 | -0.1679 | No | ||
70 | EHF | 4560088 | 9546 | -0.027 | -0.1731 | No | ||
71 | GAB2 | 1410280 2340520 4280040 | 9815 | -0.033 | -0.1874 | No | ||
72 | PAX6 | 1190025 | 9850 | -0.033 | -0.1890 | No | ||
73 | PGM2L1 | 2350035 | 9909 | -0.035 | -0.1920 | No | ||
74 | TIAL1 | 4150048 6510605 | 9953 | -0.036 | -0.1941 | No | ||
75 | BDNF | 2940128 3520368 | 9969 | -0.036 | -0.1947 | No | ||
76 | KAZALD1 | 380603 | 10129 | -0.040 | -0.2031 | No | ||
77 | GTF2H1 | 2570746 2650148 | 10462 | -0.047 | -0.2208 | No | ||
78 | SNCG | 3120725 | 10546 | -0.049 | -0.2250 | No | ||
79 | IPO7 | 2190746 | 10918 | -0.057 | -0.2448 | No | ||
80 | NCF2 | 540129 2370441 2650133 | 11099 | -0.061 | -0.2542 | No | ||
81 | ITPKB | 2900195 7100039 | 11131 | -0.062 | -0.2555 | No | ||
82 | SV2A | 1450039 5570685 | 11304 | -0.068 | -0.2644 | No | ||
83 | CUGBP1 | 450292 510022 7050176 7050215 | 11467 | -0.073 | -0.2727 | No | ||
84 | ETV3 | 5360487 | 11554 | -0.076 | -0.2770 | No | ||
85 | ANKRD1 | 4850685 | 11902 | -0.089 | -0.2952 | No | ||
86 | MMP7 | 1780497 | 11916 | -0.089 | -0.2954 | No | ||
87 | CACNA1E | 840253 | 12261 | -0.104 | -0.3135 | No | ||
88 | ARF3 | 3710446 | 12677 | -0.128 | -0.3352 | No | ||
89 | FUCA1 | 610075 | 12722 | -0.131 | -0.3368 | No | ||
90 | RAB39 | 430524 | 12824 | -0.138 | -0.3415 | No | ||
91 | CYR61 | 1240408 5290026 4120452 6550008 | 12825 | -0.138 | -0.3407 | No | ||
92 | FGF23 | 510746 | 12973 | -0.149 | -0.3477 | No | ||
93 | GPD1 | 2480095 | 13040 | -0.154 | -0.3504 | No | ||
94 | ADAMTS4 | 430435 | 13074 | -0.156 | -0.3513 | No | ||
95 | PRDX6 | 4920397 6380601 | 13270 | -0.171 | -0.3608 | No | ||
96 | ST7L | 840735 2360576 | 13333 | -0.176 | -0.3632 | No | ||
97 | GPR120 | 2350398 | 13459 | -0.187 | -0.3688 | No | ||
98 | LTBR | 2450341 | 13633 | -0.209 | -0.3770 | No | ||
99 | TAF5 | 3450288 5890193 6860435 | 14025 | -0.254 | -0.3967 | No | ||
100 | DMBT1 | 7050270 | 14170 | -0.276 | -0.4029 | No | ||
101 | NRGN | 4280433 | 14300 | -0.297 | -0.4081 | No | ||
102 | SLC26A9 | 3440722 5340088 7510093 | 14460 | -0.324 | -0.4148 | No | ||
103 | CENTD2 | 60408 2510156 6100494 | 14505 | -0.332 | -0.4153 | No | ||
104 | NDUFS2 | 4850020 6200402 | 14525 | -0.335 | -0.4143 | No | ||
105 | MMRN2 | 1740047 | 14773 | -0.386 | -0.4254 | No | ||
106 | EPHA2 | 5890056 | 14854 | -0.403 | -0.4274 | No | ||
107 | CDKN2C | 5050750 5130148 | 15096 | -0.464 | -0.4377 | No | ||
108 | PLCB3 | 4670402 | 15112 | -0.469 | -0.4358 | No | ||
109 | SRRM1 | 6110025 | 15118 | -0.469 | -0.4333 | No | ||
110 | EPC1 | 1570050 5290095 6900193 | 15244 | -0.514 | -0.4371 | No | ||
111 | CAMK1D | 1660100 2350309 | 15369 | -0.557 | -0.4405 | No | ||
112 | CAP1 | 2650278 | 15489 | -0.600 | -0.4435 | No | ||
113 | CD53 | 5550162 | 15520 | -0.609 | -0.4415 | No | ||
114 | BCL2L14 | 2940279 | 15583 | -0.636 | -0.4411 | No | ||
115 | RUNX3 | 3800546 | 15769 | -0.719 | -0.4469 | No | ||
116 | TMEM24 | 5860039 | 15819 | -0.746 | -0.4452 | No | ||
117 | LAG3 | 6860112 | 15838 | -0.761 | -0.4417 | No | ||
118 | ZRANB1 | 510373 4540278 | 16045 | -0.867 | -0.4478 | Yes | ||
119 | NUMA1 | 6520576 | 16107 | -0.904 | -0.4458 | Yes | ||
120 | BLNK | 70288 6590092 | 16165 | -0.941 | -0.4434 | Yes | ||
121 | KCNQ1 | 1580050 6860441 | 16168 | -0.942 | -0.4380 | Yes | ||
122 | MFN2 | 2260195 6100164 | 16277 | -1.001 | -0.4379 | Yes | ||
123 | KCNAB2 | 4850315 | 16340 | -1.032 | -0.4352 | Yes | ||
124 | SPI1 | 1410397 | 16408 | -1.071 | -0.4326 | Yes | ||
125 | CD3E | 3800056 | 16584 | -1.180 | -0.4352 | Yes | ||
126 | DPP3 | 2680725 3780670 | 16645 | -1.228 | -0.4312 | Yes | ||
127 | SYTL1 | 510487 | 16683 | -1.252 | -0.4259 | Yes | ||
128 | SELP | 6040193 | 16859 | -1.406 | -0.4271 | Yes | ||
129 | PBXIP1 | 70131 | 16904 | -1.442 | -0.4210 | Yes | ||
130 | SLC35C1 | 4540154 | 16933 | -1.462 | -0.4140 | Yes | ||
131 | SIPA1 | 5220687 | 17003 | -1.500 | -0.4089 | Yes | ||
132 | UNC93B1 | 430152 | 17011 | -1.505 | -0.4004 | Yes | ||
133 | SSBP3 | 870717 1050377 7040551 | 17013 | -1.506 | -0.3917 | Yes | ||
134 | LCK | 3360142 | 17025 | -1.510 | -0.3834 | Yes | ||
135 | ESRRA | 6550242 | 17060 | -1.530 | -0.3763 | Yes | ||
136 | SLAMF9 | 3710300 | 17107 | -1.564 | -0.3696 | Yes | ||
137 | ARHGDIB | 4730433 | 17365 | -1.773 | -0.3731 | Yes | ||
138 | MAP4K2 | 4200037 | 17427 | -1.841 | -0.3656 | Yes | ||
139 | TNNI2 | 5910739 | 17436 | -1.850 | -0.3552 | Yes | ||
140 | DGKZ | 3460041 6400129 | 17689 | -2.098 | -0.3565 | Yes | ||
141 | PRF1 | 6660309 | 17753 | -2.187 | -0.3471 | Yes | ||
142 | SELL | 1190500 | 17775 | -2.211 | -0.3353 | Yes | ||
143 | CTSW | 360368 | 17793 | -2.238 | -0.3231 | Yes | ||
144 | SLC2A3 | 1990377 | 17930 | -2.432 | -0.3162 | Yes | ||
145 | ADRBK1 | 1340333 | 17948 | -2.469 | -0.3026 | Yes | ||
146 | TYSND1 | 2940273 | 17968 | -2.496 | -0.2890 | Yes | ||
147 | RPS6KA4 | 2190524 | 18080 | -2.652 | -0.2795 | Yes | ||
148 | ZNF289 | 3610390 3870711 3940138 5340373 | 18131 | -2.746 | -0.2661 | Yes | ||
149 | PIK4CB | 510450 1780452 | 18198 | -2.874 | -0.2528 | Yes | ||
150 | PTPN6 | 4230128 | 18276 | -3.085 | -0.2389 | Yes | ||
151 | ELOVL1 | 2450019 4760138 5340685 | 18348 | -3.294 | -0.2234 | Yes | ||
152 | POU2AF1 | 5690242 | 18386 | -3.410 | -0.2054 | Yes | ||
153 | TCIRG1 | 4590524 5910079 6900619 | 18486 | -3.880 | -0.1880 | Yes | ||
154 | POLD4 | 2320082 | 18553 | -4.501 | -0.1651 | Yes | ||
155 | LPXN | 2360142 | 18579 | -4.933 | -0.1376 | Yes | ||
156 | RHOG | 6760575 | 18589 | -5.267 | -0.1072 | Yes | ||
157 | CD5 | 6590338 | 18607 | -6.037 | -0.0727 | Yes | ||
158 | IL2RA | 6620450 | 18608 | -6.074 | -0.0370 | Yes | ||
159 | MAPKAPK2 | 2850500 | 18609 | -6.376 | 0.0004 | Yes |