Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$PAX_Q6 |
Enrichment Score (ES) | -0.44144613 |
Normalized Enrichment Score (NES) | -1.2783636 |
Nominal p-value | 0.0228385 |
FDR q-value | 0.9416363 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | METAP1 | 3520632 | 121 | 4.035 | 0.0251 | No | ||
2 | LUC7L | 6040156 6110411 | 322 | 3.137 | 0.0389 | No | ||
3 | OSBPL9 | 2570373 | 703 | 2.316 | 0.0364 | No | ||
4 | STIP1 | 6450390 | 774 | 2.205 | 0.0500 | No | ||
5 | BTG1 | 4200735 6040131 6200133 | 783 | 2.195 | 0.0668 | No | ||
6 | PPID | 2680707 | 914 | 2.022 | 0.0756 | No | ||
7 | SLIT3 | 7100132 | 1025 | 1.864 | 0.0842 | No | ||
8 | RUNX1 | 3840711 | 1043 | 1.837 | 0.0977 | No | ||
9 | SOCS2 | 4760692 | 1124 | 1.751 | 0.1071 | No | ||
10 | MCTS1 | 6130133 | 1148 | 1.732 | 0.1195 | No | ||
11 | LDB1 | 5270601 | 1263 | 1.597 | 0.1258 | No | ||
12 | BZW1 | 460270 | 1269 | 1.584 | 0.1380 | No | ||
13 | MBNL1 | 2640762 7100048 | 1576 | 1.263 | 0.1313 | No | ||
14 | MAP2K6 | 1230056 2940204 | 1761 | 1.102 | 0.1300 | No | ||
15 | UBE2H | 1980142 2970079 | 1882 | 1.024 | 0.1315 | No | ||
16 | GATA3 | 6130068 | 1948 | 0.991 | 0.1358 | No | ||
17 | MYADM | 4230132 | 2099 | 0.905 | 0.1347 | No | ||
18 | PPARGC1B | 3290114 | 2235 | 0.828 | 0.1339 | No | ||
19 | PPP1R12A | 4070066 4590162 | 2393 | 0.748 | 0.1313 | No | ||
20 | HHEX | 2340575 | 2457 | 0.703 | 0.1334 | No | ||
21 | MOSPD1 | 2030170 5270156 6900142 | 2614 | 0.626 | 0.1298 | No | ||
22 | CHD2 | 4070039 | 2653 | 0.611 | 0.1326 | No | ||
23 | GPR85 | 5130750 5910020 | 2823 | 0.530 | 0.1276 | No | ||
24 | NEDD4 | 460736 1190280 | 3060 | 0.438 | 0.1182 | No | ||
25 | DNTTIP1 | 5360537 | 3164 | 0.403 | 0.1158 | No | ||
26 | AMOTL1 | 380279 | 3267 | 0.370 | 0.1131 | No | ||
27 | SP6 | 60484 510452 2690333 | 3275 | 0.366 | 0.1156 | No | ||
28 | SLCO3A1 | 1050408 2370156 6110072 | 3287 | 0.360 | 0.1179 | No | ||
29 | BCL2L2 | 2760692 6770739 | 3496 | 0.296 | 0.1089 | No | ||
30 | EN1 | 5360168 7050025 | 3547 | 0.281 | 0.1084 | No | ||
31 | RNF34 | 3800332 4590717 5670138 | 3728 | 0.232 | 0.1004 | No | ||
32 | LUZP1 | 940075 4280458 6180070 | 3827 | 0.213 | 0.0968 | No | ||
33 | AMD1 | 6290128 | 3943 | 0.188 | 0.0920 | No | ||
34 | ITGA7 | 1230739 | 4433 | 0.120 | 0.0664 | No | ||
35 | HAVCR2 | 6860592 | 4465 | 0.116 | 0.0657 | No | ||
36 | KCNA2 | 5080403 | 4589 | 0.105 | 0.0598 | No | ||
37 | ATF3 | 1940546 | 4592 | 0.105 | 0.0605 | No | ||
38 | ZIC3 | 380020 | 4656 | 0.100 | 0.0579 | No | ||
39 | PTCH2 | 2900092 | 4712 | 0.096 | 0.0557 | No | ||
40 | NTRK1 | 6400538 | 4783 | 0.091 | 0.0526 | No | ||
41 | PFTK1 | 1780181 | 4849 | 0.086 | 0.0497 | No | ||
42 | DHH | 2120433 | 5129 | 0.070 | 0.0351 | No | ||
43 | SEMA3A | 1780064 | 5354 | 0.061 | 0.0235 | No | ||
44 | KCNIP2 | 60088 1780324 | 5484 | 0.055 | 0.0169 | No | ||
45 | T | 6370164 | 5505 | 0.055 | 0.0162 | No | ||
46 | OIT3 | 1660152 | 5841 | 0.044 | -0.0016 | No | ||
47 | SNCAIP | 4010551 | 5880 | 0.043 | -0.0033 | No | ||
48 | ARHGAP12 | 1050181 | 6060 | 0.038 | -0.0127 | No | ||
49 | IRX3 | 4200112 | 6144 | 0.036 | -0.0169 | No | ||
50 | BNC1 | 5550427 | 6213 | 0.034 | -0.0204 | No | ||
51 | CHRND | 840403 2260670 | 6257 | 0.033 | -0.0224 | No | ||
52 | GSC | 1580685 | 6340 | 0.030 | -0.0267 | No | ||
53 | HOXD3 | 6450154 | 6348 | 0.030 | -0.0268 | No | ||
54 | SKIL | 1090364 | 6355 | 0.030 | -0.0269 | No | ||
55 | HOXB9 | 2640687 | 6386 | 0.029 | -0.0283 | No | ||
56 | HNF4G | 5720451 | 6615 | 0.025 | -0.0405 | No | ||
57 | MYF6 | 2690576 | 6715 | 0.022 | -0.0457 | No | ||
58 | EMX2 | 1660092 | 6718 | 0.022 | -0.0456 | No | ||
59 | UPK2 | 60176 | 6779 | 0.021 | -0.0487 | No | ||
60 | ACCN1 | 2060139 2190541 | 6786 | 0.021 | -0.0488 | No | ||
61 | TGFB3 | 1070041 | 6952 | 0.017 | -0.0577 | No | ||
62 | TEAD1 | 2470551 | 7024 | 0.016 | -0.0614 | No | ||
63 | CRYGB | 2340593 | 7069 | 0.016 | -0.0636 | No | ||
64 | SPRY2 | 5860184 | 7168 | 0.014 | -0.0689 | No | ||
65 | GTPBP1 | 2230541 4560528 | 7235 | 0.012 | -0.0723 | No | ||
66 | P4HA2 | 1090546 | 7513 | 0.007 | -0.0873 | No | ||
67 | CHML | 6650156 | 7613 | 0.005 | -0.0926 | No | ||
68 | CHRDL1 | 1580037 6380204 | 7866 | 0.001 | -0.1063 | No | ||
69 | CP | 2570484 | 7882 | 0.001 | -0.1071 | No | ||
70 | TAL1 | 7040239 | 7996 | -0.001 | -0.1132 | No | ||
71 | BMP5 | 4670048 | 8035 | -0.001 | -0.1153 | No | ||
72 | SP7 | 1050315 | 8171 | -0.004 | -0.1226 | No | ||
73 | BET1 | 4010725 | 8281 | -0.006 | -0.1284 | No | ||
74 | PLAC1 | 2350594 | 8325 | -0.006 | -0.1307 | No | ||
75 | NKX2-8 | 50022 | 8460 | -0.009 | -0.1379 | No | ||
76 | TMPRSS5 | 4060068 | 8465 | -0.009 | -0.1381 | No | ||
77 | HNT | 6450731 | 8470 | -0.009 | -0.1382 | No | ||
78 | PDHA2 | 2630438 | 8522 | -0.010 | -0.1409 | No | ||
79 | CRLF1 | 3520092 | 8580 | -0.010 | -0.1439 | No | ||
80 | ADRA2C | 5130154 | 8704 | -0.013 | -0.1505 | No | ||
81 | JAG1 | 3440390 | 8849 | -0.015 | -0.1582 | No | ||
82 | XPR1 | 1500093 | 8871 | -0.015 | -0.1592 | No | ||
83 | SPTBN4 | 4150279 5270286 | 8887 | -0.016 | -0.1599 | No | ||
84 | PAX3 | 50551 | 8971 | -0.017 | -0.1643 | No | ||
85 | CDH16 | 1450129 | 8982 | -0.017 | -0.1647 | No | ||
86 | SFTPC | 3290133 | 9209 | -0.021 | -0.1768 | No | ||
87 | LMO4 | 3800746 | 9219 | -0.021 | -0.1771 | No | ||
88 | GRIA1 | 1340152 3780750 4920440 | 9247 | -0.022 | -0.1784 | No | ||
89 | TGFBR1 | 1400148 4280020 6550711 | 9267 | -0.022 | -0.1792 | No | ||
90 | SRPX | 580717 1980162 | 9313 | -0.023 | -0.1815 | No | ||
91 | FGF14 | 2630390 3520075 6770048 | 9393 | -0.024 | -0.1856 | No | ||
92 | PRRX1 | 4120193 4480390 | 9563 | -0.028 | -0.1946 | No | ||
93 | PRDM1 | 3170347 3520301 | 9666 | -0.030 | -0.1999 | No | ||
94 | GJB1 | 1240441 | 9777 | -0.032 | -0.2056 | No | ||
95 | FOXA1 | 3710609 | 9825 | -0.033 | -0.2079 | No | ||
96 | SLC26A7 | 1850398 3830377 | 9848 | -0.033 | -0.2088 | No | ||
97 | BDNF | 2940128 3520368 | 9969 | -0.036 | -0.2150 | No | ||
98 | SPATS2 | 2360066 | 10071 | -0.039 | -0.2202 | No | ||
99 | NRG1 | 1050332 | 10091 | -0.039 | -0.2209 | No | ||
100 | ELP4 | 1230576 | 10132 | -0.040 | -0.2228 | No | ||
101 | HOXA5 | 6840026 | 10312 | -0.043 | -0.2322 | No | ||
102 | RCL1 | 1980408 2680008 3800176 | 10670 | -0.051 | -0.2511 | No | ||
103 | TRIB1 | 2320435 | 10969 | -0.058 | -0.2668 | No | ||
104 | MOBKL2C | 2640088 3830017 | 11039 | -0.060 | -0.2701 | No | ||
105 | A2M | 6620039 | 11082 | -0.061 | -0.2719 | No | ||
106 | RFX4 | 3710100 5340215 | 11234 | -0.065 | -0.2796 | No | ||
107 | NRP2 | 4070400 5860041 6650446 | 11605 | -0.077 | -0.2990 | No | ||
108 | FGF10 | 730458 840706 | 11639 | -0.079 | -0.3002 | No | ||
109 | VWF | 4670519 | 11758 | -0.083 | -0.3060 | No | ||
110 | RFX5 | 5420128 | 11955 | -0.091 | -0.3159 | No | ||
111 | OTOP2 | 610068 | 12093 | -0.096 | -0.3226 | No | ||
112 | MUSK | 1190113 | 12205 | -0.101 | -0.3278 | No | ||
113 | PPARD | 110131 | 12378 | -0.111 | -0.3363 | No | ||
114 | SLITRK5 | 6590292 | 12444 | -0.115 | -0.3389 | No | ||
115 | USH1G | 2940446 | 12481 | -0.116 | -0.3399 | No | ||
116 | B4GALT5 | 1230692 | 12700 | -0.129 | -0.3507 | No | ||
117 | HOXC4 | 1940193 | 12761 | -0.134 | -0.3529 | No | ||
118 | CYR61 | 1240408 5290026 4120452 6550008 | 12825 | -0.138 | -0.3553 | No | ||
119 | BRS3 | 1740403 | 12835 | -0.138 | -0.3547 | No | ||
120 | BRUNOL4 | 4490452 5080451 | 13175 | -0.164 | -0.3718 | No | ||
121 | MYO18B | 7100670 | 13215 | -0.167 | -0.3726 | No | ||
122 | FLNC | 2360048 5050270 | 13267 | -0.171 | -0.3740 | No | ||
123 | CHRNA2 | 5050315 | 13590 | -0.205 | -0.3899 | No | ||
124 | DOCK4 | 5910102 | 13805 | -0.229 | -0.3997 | No | ||
125 | TRPM3 | 2470110 6400731 6550047 | 13949 | -0.245 | -0.4055 | No | ||
126 | LRRK1 | 2810609 | 13990 | -0.250 | -0.4057 | No | ||
127 | TNKS1BP1 | 7040184 | 13996 | -0.250 | -0.4040 | No | ||
128 | TAF5 | 3450288 5890193 6860435 | 14025 | -0.254 | -0.4036 | No | ||
129 | GNB4 | 3390079 4230035 | 14096 | -0.265 | -0.4053 | No | ||
130 | ITGB4 | 1740021 3840482 | 14098 | -0.265 | -0.4033 | No | ||
131 | CASKIN2 | 2030113 | 14248 | -0.288 | -0.4091 | No | ||
132 | PHACTR3 | 3850435 5900445 | 14280 | -0.294 | -0.4084 | No | ||
133 | SYNPO2L | 5390719 | 14360 | -0.308 | -0.4103 | No | ||
134 | OFCC1 | 2060392 | 14377 | -0.311 | -0.4087 | No | ||
135 | HOXB2 | 6450592 | 14396 | -0.314 | -0.4072 | No | ||
136 | ATP2C1 | 2630446 6520253 | 14495 | -0.331 | -0.4100 | No | ||
137 | SFXN2 | 2650563 3140095 3830762 3870398 | 14527 | -0.335 | -0.4090 | No | ||
138 | JMJD2B | 6350372 6400471 | 14776 | -0.387 | -0.4194 | No | ||
139 | PTK7 | 380315 | 14860 | -0.404 | -0.4208 | No | ||
140 | BLVRB | 7040707 | 14886 | -0.410 | -0.4189 | No | ||
141 | ACTN3 | 3140541 6480598 | 14918 | -0.418 | -0.4173 | No | ||
142 | GRAP2 | 7100441 1410647 | 15117 | -0.469 | -0.4244 | No | ||
143 | PRG4 | 5860156 6650086 | 15433 | -0.581 | -0.4369 | Yes | ||
144 | EGR3 | 6940128 | 15440 | -0.582 | -0.4326 | Yes | ||
145 | WWOX | 510008 870524 1090114 | 15454 | -0.588 | -0.4287 | Yes | ||
146 | TNFSF10 | 3170300 | 15472 | -0.594 | -0.4250 | Yes | ||
147 | HIRA | 4480609 5270167 | 15491 | -0.601 | -0.4212 | Yes | ||
148 | CHN2 | 870528 | 15664 | -0.671 | -0.4253 | Yes | ||
149 | TPM3 | 670600 3170296 5670167 6650471 | 15740 | -0.702 | -0.4239 | Yes | ||
150 | GATA1 | 6400068 | 15914 | -0.799 | -0.4270 | Yes | ||
151 | LMAN2 | 430154 | 16064 | -0.876 | -0.4282 | Yes | ||
152 | MRPL40 | 2370215 | 16192 | -0.951 | -0.4276 | Yes | ||
153 | TWIST1 | 5130619 | 16286 | -1.005 | -0.4248 | Yes | ||
154 | RGS3 | 60670 540736 1340180 1500369 3390735 4010131 4610402 6380114 | 16462 | -1.101 | -0.4256 | Yes | ||
155 | ARL3 | 5690725 | 16628 | -1.217 | -0.4250 | Yes | ||
156 | SLC1A4 | 5290064 | 16693 | -1.264 | -0.4186 | Yes | ||
157 | LENG9 | 3060072 | 16739 | -1.294 | -0.4108 | Yes | ||
158 | SERPING1 | 5550440 | 16795 | -1.332 | -0.4034 | Yes | ||
159 | IER3 | 5860021 | 16843 | -1.389 | -0.3950 | Yes | ||
160 | NFATC1 | 510400 2320348 4050600 6180161 6290136 6620086 | 16879 | -1.420 | -0.3858 | Yes | ||
161 | CACNA2D3 | 4010184 | 16974 | -1.486 | -0.3792 | Yes | ||
162 | TIGD3 | 3850576 | 17029 | -1.511 | -0.3703 | Yes | ||
163 | BATF | 6760390 | 17115 | -1.569 | -0.3626 | Yes | ||
164 | ETV6 | 610524 | 17150 | -1.594 | -0.3519 | Yes | ||
165 | TBCC | 4810021 | 17300 | -1.723 | -0.3465 | Yes | ||
166 | MRPS6 | 870164 | 17362 | -1.772 | -0.3359 | Yes | ||
167 | UBE2C | 6130017 | 17457 | -1.873 | -0.3263 | Yes | ||
168 | FEZ2 | 5910181 | 17498 | -1.902 | -0.3135 | Yes | ||
169 | THAP7 | 6660673 | 17615 | -2.020 | -0.3039 | Yes | ||
170 | TBC1D17 | 1780450 | 17803 | -2.248 | -0.2964 | Yes | ||
171 | MRPL27 | 2060131 | 17850 | -2.304 | -0.2808 | Yes | ||
172 | FBXO36 | 1410086 | 17876 | -2.343 | -0.2638 | Yes | ||
173 | WBP1 | 6100066 | 17967 | -2.495 | -0.2491 | Yes | ||
174 | TLE3 | 580040 4730121 | 18007 | -2.546 | -0.2312 | Yes | ||
175 | PPP1R9B | 3130619 | 18017 | -2.558 | -0.2116 | Yes | ||
176 | ETV5 | 110017 | 18034 | -2.603 | -0.1921 | Yes | ||
177 | ICAM1 | 6980138 | 18039 | -2.609 | -0.1718 | Yes | ||
178 | EGLN2 | 540086 | 18073 | -2.645 | -0.1528 | Yes | ||
179 | PRKCH | 5720079 | 18256 | -3.044 | -0.1388 | Yes | ||
180 | PTPN6 | 4230128 | 18276 | -3.085 | -0.1156 | Yes | ||
181 | BCL9L | 6940053 | 18318 | -3.207 | -0.0927 | Yes | ||
182 | AKT1S1 | 1660048 | 18416 | -3.525 | -0.0703 | Yes | ||
183 | EDG5 | 2640300 | 18466 | -3.760 | -0.0434 | Yes | ||
184 | FLOT1 | 1660575 1690040 | 18614 | -6.562 | 0.0001 | Yes |