Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q6 |
Enrichment Score (ES) | 0.59040076 |
Normalized Enrichment Score (NES) | 1.7373707 |
Nominal p-value | 0.0 |
FDR q-value | 0.006688236 |
FWER p-Value | 0.053 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GSPT1 | 5420050 | 18 | 5.469 | 0.0335 | Yes | ||
2 | PPM1D | 1690193 | 24 | 5.188 | 0.0660 | Yes | ||
3 | SFRS1 | 2360440 | 39 | 4.846 | 0.0958 | Yes | ||
4 | CTCF | 5340017 | 61 | 4.586 | 0.1236 | Yes | ||
5 | UGCGL1 | 4230072 | 63 | 4.528 | 0.1521 | Yes | ||
6 | TMPO | 4050494 | 74 | 4.448 | 0.1796 | Yes | ||
7 | ZCCHC8 | 2260332 2350487 | 105 | 4.140 | 0.2041 | Yes | ||
8 | EED | 2320373 | 110 | 4.095 | 0.2298 | Yes | ||
9 | CDCA7 | 3060097 | 118 | 4.044 | 0.2549 | Yes | ||
10 | RBL1 | 3130372 | 151 | 3.829 | 0.2773 | Yes | ||
11 | KPNB1 | 1690138 | 152 | 3.826 | 0.3015 | Yes | ||
12 | BRMS1L | 6110609 | 154 | 3.813 | 0.3255 | Yes | ||
13 | PHC1 | 520195 | 171 | 3.750 | 0.3483 | Yes | ||
14 | MCM4 | 2760673 5420711 | 225 | 3.505 | 0.3675 | Yes | ||
15 | DCK | 6900411 | 283 | 3.283 | 0.3851 | Yes | ||
16 | SOAT1 | 1190019 | 288 | 3.267 | 0.4055 | Yes | ||
17 | NASP | 2260139 2940369 5130707 | 312 | 3.185 | 0.4244 | Yes | ||
18 | PCNA | 940754 | 337 | 3.090 | 0.4426 | Yes | ||
19 | DNMT1 | 2260097 | 405 | 2.929 | 0.4574 | Yes | ||
20 | POLD3 | 6400278 | 499 | 2.715 | 0.4695 | Yes | ||
21 | HTF9C | 3190048 4120132 | 583 | 2.513 | 0.4809 | Yes | ||
22 | H2AFZ | 1470168 | 673 | 2.360 | 0.4909 | Yes | ||
23 | ALDH6A1 | 1770746 | 1035 | 1.852 | 0.4831 | Yes | ||
24 | PRPS1 | 6350129 | 1049 | 1.834 | 0.4939 | Yes | ||
25 | ACO2 | 4230600 | 1057 | 1.827 | 0.5051 | Yes | ||
26 | POLE4 | 6860097 | 1103 | 1.773 | 0.5138 | Yes | ||
27 | STMN1 | 1990717 | 1146 | 1.733 | 0.5225 | Yes | ||
28 | CDC25A | 3800184 | 1196 | 1.670 | 0.5304 | Yes | ||
29 | NCL | 2360463 4540279 | 1310 | 1.541 | 0.5340 | Yes | ||
30 | ILF3 | 940722 3190647 6520110 | 1392 | 1.453 | 0.5388 | Yes | ||
31 | HNRPA1 | 4670398 5050687 | 1396 | 1.449 | 0.5478 | Yes | ||
32 | SUMO1 | 1990364 2760338 6380195 | 1458 | 1.382 | 0.5532 | Yes | ||
33 | MCM6 | 60092 540181 6510110 | 1526 | 1.312 | 0.5578 | Yes | ||
34 | E2F1 | 5360093 | 1556 | 1.284 | 0.5643 | Yes | ||
35 | FANCD2 | 1850280 6840348 | 1699 | 1.150 | 0.5639 | Yes | ||
36 | UFD1L | 870020 | 1773 | 1.092 | 0.5668 | Yes | ||
37 | SFRS7 | 2760408 | 1858 | 1.040 | 0.5689 | Yes | ||
38 | AK2 | 4590458 4760195 6110097 | 1878 | 1.028 | 0.5743 | Yes | ||
39 | PPP1CC | 6380300 2510647 | 1943 | 0.993 | 0.5771 | Yes | ||
40 | NOLC1 | 2350195 | 1964 | 0.983 | 0.5822 | Yes | ||
41 | GMNN | 2630148 | 1999 | 0.965 | 0.5865 | Yes | ||
42 | SNRPD1 | 4480162 | 2196 | 0.847 | 0.5812 | Yes | ||
43 | PHF5A | 2690519 | 2377 | 0.753 | 0.5762 | Yes | ||
44 | DNAJC11 | 360465 3390215 | 2423 | 0.723 | 0.5783 | Yes | ||
45 | MYH10 | 2640673 | 2426 | 0.718 | 0.5828 | Yes | ||
46 | MCM3 | 5570068 | 2610 | 0.627 | 0.5768 | Yes | ||
47 | RAB11B | 3990609 | 2644 | 0.614 | 0.5789 | Yes | ||
48 | MCM7 | 3290292 5220056 | 2662 | 0.607 | 0.5818 | Yes | ||
49 | USP37 | 2470433 | 2706 | 0.580 | 0.5831 | Yes | ||
50 | CDC6 | 4570296 5360600 | 2713 | 0.578 | 0.5865 | Yes | ||
51 | PHF15 | 6550066 6860673 | 2851 | 0.521 | 0.5823 | Yes | ||
52 | CDT1 | 3780682 | 2867 | 0.514 | 0.5848 | Yes | ||
53 | EZH2 | 6130605 6380524 | 2881 | 0.506 | 0.5873 | Yes | ||
54 | MSH2 | 6180273 | 2927 | 0.488 | 0.5879 | Yes | ||
55 | CLSPN | 2190239 2630687 5550632 | 2938 | 0.483 | 0.5904 | Yes | ||
56 | TBX6 | 4730139 6840647 | 3002 | 0.462 | 0.5899 | No | ||
57 | SLC38A1 | 520465 | 3087 | 0.429 | 0.5881 | No | ||
58 | SLCO3A1 | 1050408 2370156 6110072 | 3287 | 0.360 | 0.5796 | No | ||
59 | E2F3 | 50162 460180 | 3320 | 0.350 | 0.5800 | No | ||
60 | HIST1H2AH | 3710333 | 3331 | 0.348 | 0.5817 | No | ||
61 | WEE1 | 3390070 | 3430 | 0.317 | 0.5784 | No | ||
62 | CDC45L | 70537 3130114 | 3466 | 0.305 | 0.5784 | No | ||
63 | ASXL2 | 130670 | 3506 | 0.294 | 0.5782 | No | ||
64 | CORT | 360008 2340092 | 3541 | 0.283 | 0.5781 | No | ||
65 | ADAMTS2 | 2650025 6370133 6840670 | 3598 | 0.265 | 0.5767 | No | ||
66 | STAG2 | 4540132 | 3638 | 0.254 | 0.5762 | No | ||
67 | PPP1R8 | 6290292 | 3785 | 0.219 | 0.5697 | No | ||
68 | ERBB2IP | 580253 1090672 | 3909 | 0.196 | 0.5643 | No | ||
69 | POLA2 | 940519 | 4144 | 0.155 | 0.5526 | No | ||
70 | HS6ST3 | 5910138 | 4439 | 0.119 | 0.5374 | No | ||
71 | HNRPD | 4120021 | 4486 | 0.114 | 0.5356 | No | ||
72 | E2F7 | 4200056 | 4524 | 0.111 | 0.5343 | No | ||
73 | FHOD1 | 2680279 | 4555 | 0.108 | 0.5334 | No | ||
74 | TOPBP1 | 6020333 | 4595 | 0.105 | 0.5319 | No | ||
75 | SP3 | 3840338 | 5216 | 0.066 | 0.4988 | No | ||
76 | KCNA6 | 450291 1400086 1660291 2470576 | 5558 | 0.053 | 0.4807 | No | ||
77 | PCSK1 | 2350148 | 5571 | 0.053 | 0.4803 | No | ||
78 | PRPF4B | 940181 2570300 | 5905 | 0.042 | 0.4626 | No | ||
79 | UXT | 110019 5080066 | 5961 | 0.041 | 0.4598 | No | ||
80 | JPH1 | 610739 | 6081 | 0.037 | 0.4536 | No | ||
81 | GRIA4 | 2640131 | 6252 | 0.033 | 0.4446 | No | ||
82 | FMO4 | 360735 | 6310 | 0.031 | 0.4417 | No | ||
83 | RHD | 4050168 | 6672 | 0.023 | 0.4223 | No | ||
84 | SLC6A4 | 2230372 | 6727 | 0.022 | 0.4196 | No | ||
85 | SMAD6 | 870504 | 6850 | 0.019 | 0.4131 | No | ||
86 | RQCD1 | 1850139 | 7199 | 0.013 | 0.3943 | No | ||
87 | STAG1 | 1190300 1400722 4590100 | 7962 | -0.000 | 0.3530 | No | ||
88 | NUP153 | 7000452 | 8186 | -0.004 | 0.3410 | No | ||
89 | FBXO5 | 2630551 | 8235 | -0.005 | 0.3384 | No | ||
90 | ARHGAP6 | 2060121 | 8632 | -0.011 | 0.3170 | No | ||
91 | CBX5 | 3830072 6290167 | 8836 | -0.015 | 0.3061 | No | ||
92 | GABRB3 | 4150164 | 8891 | -0.016 | 0.3033 | No | ||
93 | PRKDC | 1400072 4230541 | 9467 | -0.026 | 0.2723 | No | ||
94 | TREX2 | 4920707 | 9493 | -0.027 | 0.2712 | No | ||
95 | INSM1 | 3450671 | 9698 | -0.030 | 0.2603 | No | ||
96 | PAX6 | 1190025 | 9850 | -0.033 | 0.2523 | No | ||
97 | POLE2 | 6110041 | 9924 | -0.035 | 0.2486 | No | ||
98 | EFNA5 | 460707 2190519 | 10306 | -0.043 | 0.2282 | No | ||
99 | DMD | 1740041 3990332 | 10389 | -0.045 | 0.2241 | No | ||
100 | GPRC5B | 2760114 | 10916 | -0.057 | 0.1960 | No | ||
101 | IPO7 | 2190746 | 10918 | -0.057 | 0.1963 | No | ||
102 | STK35 | 2360121 | 11527 | -0.075 | 0.1638 | No | ||
103 | NRP2 | 4070400 5860041 6650446 | 11605 | -0.077 | 0.1601 | No | ||
104 | PODN | 3710068 | 11862 | -0.087 | 0.1468 | No | ||
105 | MCM2 | 5050139 | 11994 | -0.092 | 0.1403 | No | ||
106 | RAD51 | 6110450 6980280 | 12021 | -0.093 | 0.1395 | No | ||
107 | DNAJC9 | 6130019 | 12121 | -0.098 | 0.1347 | No | ||
108 | EPHB1 | 4610056 | 12404 | -0.113 | 0.1202 | No | ||
109 | MCM8 | 6130743 | 12548 | -0.120 | 0.1132 | No | ||
110 | CASP8AP2 | 5910593 | 12572 | -0.121 | 0.1127 | No | ||
111 | ARID4A | 520156 1050707 | 12750 | -0.134 | 0.1040 | No | ||
112 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 12896 | -0.143 | 0.0970 | No | ||
113 | HNRPR | 2320440 2900601 4610008 | 13138 | -0.161 | 0.0850 | No | ||
114 | PIM1 | 630047 | 13494 | -0.191 | 0.0670 | No | ||
115 | HOXC10 | 5360170 | 13588 | -0.204 | 0.0632 | No | ||
116 | RPS6KA5 | 2120563 7040546 | 13898 | -0.239 | 0.0480 | No | ||
117 | KCND2 | 1170128 2100112 | 13984 | -0.250 | 0.0450 | No | ||
118 | SEMA5A | 6200110 6520435 | 14008 | -0.252 | 0.0453 | No | ||
119 | RANBP1 | 430215 1090180 | 14100 | -0.266 | 0.0421 | No | ||
120 | YBX2 | 3520441 | 14163 | -0.275 | 0.0404 | No | ||
121 | IL4I1 | 3190161 | 14256 | -0.291 | 0.0373 | No | ||
122 | HCN3 | 3940438 6840750 | 14393 | -0.314 | 0.0319 | No | ||
123 | ZBTB4 | 6450441 | 14441 | -0.322 | 0.0314 | No | ||
124 | HMGN2 | 3140091 | 14503 | -0.332 | 0.0302 | No | ||
125 | CCNT1 | 2450563 5390184 | 14574 | -0.345 | 0.0286 | No | ||
126 | SEMA6A | 2690138 3060021 | 14658 | -0.359 | 0.0263 | No | ||
127 | ING3 | 110438 2060390 | 14752 | -0.380 | 0.0237 | No | ||
128 | PVRL1 | 2570167 5220519 5890500 3190309 | 14778 | -0.388 | 0.0248 | No | ||
129 | NELL2 | 2340725 4280301 5420008 | 14841 | -0.399 | 0.0239 | No | ||
130 | ATAD2 | 870242 2260687 | 15095 | -0.464 | 0.0132 | No | ||
131 | DDB2 | 3520341 4610168 4850184 4920717 | 15132 | -0.473 | 0.0142 | No | ||
132 | NUP62 | 1240128 | 15339 | -0.545 | 0.0065 | No | ||
133 | POLR2A | 5220647 | 15341 | -0.546 | 0.0099 | No | ||
134 | PAQR4 | 730736 | 15378 | -0.559 | 0.0115 | No | ||
135 | PHF13 | 450435 | 15487 | -0.599 | 0.0094 | No | ||
136 | HIRA | 4480609 5270167 | 15491 | -0.601 | 0.0130 | No | ||
137 | AP4M1 | 70609 3440128 | 16156 | -0.936 | -0.0170 | No | ||
138 | MRPL40 | 2370215 | 16192 | -0.951 | -0.0129 | No | ||
139 | SFRS10 | 6130528 6400438 7040112 | 16253 | -0.992 | -0.0099 | No | ||
140 | USP52 | 3710215 6380133 | 16385 | -1.057 | -0.0103 | No | ||
141 | RRM2 | 6350059 6940162 | 16418 | -1.075 | -0.0053 | No | ||
142 | ATF5 | 5670685 | 16541 | -1.156 | -0.0046 | No | ||
143 | TYRO3 | 3130193 | 16543 | -1.158 | 0.0027 | No | ||
144 | SFRS2 | 50707 380593 | 16661 | -1.237 | 0.0041 | No | ||
145 | SYNGR4 | 6520450 | 16728 | -1.286 | 0.0087 | No | ||
146 | ACBD6 | 4200446 | 16931 | -1.462 | 0.0069 | No | ||
147 | POLD1 | 4830026 | 17474 | -1.881 | -0.0105 | No | ||
148 | MAZ | 3360121 6940750 | 17643 | -2.048 | -0.0067 | No | ||
149 | UNG | 3130110 6100364 | 17685 | -2.088 | 0.0042 | No | ||
150 | MXD3 | 6220014 | 17737 | -2.166 | 0.0151 | No | ||
151 | HIST1H4A | 1940600 | 17766 | -2.198 | 0.0275 | No | ||
152 | HIST1H2BK | 6130433 | 18216 | -2.931 | 0.0217 | No |