Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q4 |
Enrichment Score (ES) | 0.6003529 |
Normalized Enrichment Score (NES) | 1.7813005 |
Nominal p-value | 0.0 |
FDR q-value | 0.0035867046 |
FWER p-Value | 0.022 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | GSPT1 | 5420050 | 18 | 5.469 | 0.0338 | Yes | ||
2 | PPM1D | 1690193 | 24 | 5.188 | 0.0665 | Yes | ||
3 | SFRS1 | 2360440 | 39 | 4.846 | 0.0966 | Yes | ||
4 | CTCF | 5340017 | 61 | 4.586 | 0.1246 | Yes | ||
5 | UGCGL1 | 4230072 | 63 | 4.528 | 0.1534 | Yes | ||
6 | TMPO | 4050494 | 74 | 4.448 | 0.1811 | Yes | ||
7 | ZCCHC8 | 2260332 2350487 | 105 | 4.140 | 0.2058 | Yes | ||
8 | EED | 2320373 | 110 | 4.095 | 0.2317 | Yes | ||
9 | CDCA7 | 3060097 | 118 | 4.044 | 0.2570 | Yes | ||
10 | RBL1 | 3130372 | 151 | 3.829 | 0.2796 | Yes | ||
11 | KPNB1 | 1690138 | 152 | 3.826 | 0.3040 | Yes | ||
12 | BRMS1L | 6110609 | 154 | 3.813 | 0.3282 | Yes | ||
13 | PHC1 | 520195 | 171 | 3.750 | 0.3511 | Yes | ||
14 | MCM4 | 2760673 5420711 | 225 | 3.505 | 0.3706 | Yes | ||
15 | DCK | 6900411 | 283 | 3.283 | 0.3884 | Yes | ||
16 | SOAT1 | 1190019 | 288 | 3.267 | 0.4089 | Yes | ||
17 | NASP | 2260139 2940369 5130707 | 312 | 3.185 | 0.4279 | Yes | ||
18 | PCNA | 940754 | 337 | 3.090 | 0.4463 | Yes | ||
19 | DNMT1 | 2260097 | 405 | 2.929 | 0.4613 | Yes | ||
20 | POLD3 | 6400278 | 499 | 2.715 | 0.4735 | Yes | ||
21 | HTF9C | 3190048 4120132 | 583 | 2.513 | 0.4850 | Yes | ||
22 | H2AFZ | 1470168 | 673 | 2.360 | 0.4952 | Yes | ||
23 | ALDH6A1 | 1770746 | 1035 | 1.852 | 0.4874 | Yes | ||
24 | PRPS1 | 6350129 | 1049 | 1.834 | 0.4984 | Yes | ||
25 | ACO2 | 4230600 | 1057 | 1.827 | 0.5096 | Yes | ||
26 | POLE4 | 6860097 | 1103 | 1.773 | 0.5185 | Yes | ||
27 | STMN1 | 1990717 | 1146 | 1.733 | 0.5272 | Yes | ||
28 | CDC25A | 3800184 | 1196 | 1.670 | 0.5352 | Yes | ||
29 | NCL | 2360463 4540279 | 1310 | 1.541 | 0.5389 | Yes | ||
30 | ILF3 | 940722 3190647 6520110 | 1392 | 1.453 | 0.5437 | Yes | ||
31 | HNRPA1 | 4670398 5050687 | 1396 | 1.449 | 0.5528 | Yes | ||
32 | SUMO1 | 1990364 2760338 6380195 | 1458 | 1.382 | 0.5583 | Yes | ||
33 | MCM6 | 60092 540181 6510110 | 1526 | 1.312 | 0.5630 | Yes | ||
34 | E2F1 | 5360093 | 1556 | 1.284 | 0.5696 | Yes | ||
35 | FANCD2 | 1850280 6840348 | 1699 | 1.150 | 0.5692 | Yes | ||
36 | UFD1L | 870020 | 1773 | 1.092 | 0.5722 | Yes | ||
37 | SFRS7 | 2760408 | 1858 | 1.040 | 0.5742 | Yes | ||
38 | AK2 | 4590458 4760195 6110097 | 1878 | 1.028 | 0.5798 | Yes | ||
39 | PPP1CC | 6380300 2510647 | 1943 | 0.993 | 0.5826 | Yes | ||
40 | NOLC1 | 2350195 | 1964 | 0.983 | 0.5878 | Yes | ||
41 | GMNN | 2630148 | 1999 | 0.965 | 0.5921 | Yes | ||
42 | SNRPD1 | 4480162 | 2196 | 0.847 | 0.5868 | Yes | ||
43 | PHF5A | 2690519 | 2377 | 0.753 | 0.5819 | Yes | ||
44 | DNAJC11 | 360465 3390215 | 2423 | 0.723 | 0.5840 | Yes | ||
45 | MYH10 | 2640673 | 2426 | 0.718 | 0.5885 | Yes | ||
46 | MCM3 | 5570068 | 2610 | 0.627 | 0.5826 | Yes | ||
47 | RAB11B | 3990609 | 2644 | 0.614 | 0.5847 | Yes | ||
48 | CHD2 | 4070039 | 2653 | 0.611 | 0.5882 | Yes | ||
49 | MCM7 | 3290292 5220056 | 2662 | 0.607 | 0.5916 | Yes | ||
50 | USP37 | 2470433 | 2706 | 0.580 | 0.5929 | Yes | ||
51 | CDC6 | 4570296 5360600 | 2713 | 0.578 | 0.5963 | Yes | ||
52 | PHF15 | 6550066 6860673 | 2851 | 0.521 | 0.5922 | Yes | ||
53 | CDT1 | 3780682 | 2867 | 0.514 | 0.5946 | Yes | ||
54 | EZH2 | 6130605 6380524 | 2881 | 0.506 | 0.5972 | Yes | ||
55 | MSH2 | 6180273 | 2927 | 0.488 | 0.5978 | Yes | ||
56 | CLSPN | 2190239 2630687 5550632 | 2938 | 0.483 | 0.6004 | Yes | ||
57 | TBX6 | 4730139 6840647 | 3002 | 0.462 | 0.5999 | No | ||
58 | SLC38A1 | 520465 | 3087 | 0.429 | 0.5981 | No | ||
59 | SLCO3A1 | 1050408 2370156 6110072 | 3287 | 0.360 | 0.5896 | No | ||
60 | E2F3 | 50162 460180 | 3320 | 0.350 | 0.5901 | No | ||
61 | HIST1H2AH | 3710333 | 3331 | 0.348 | 0.5917 | No | ||
62 | WEE1 | 3390070 | 3430 | 0.317 | 0.5884 | No | ||
63 | CDC45L | 70537 3130114 | 3466 | 0.305 | 0.5885 | No | ||
64 | ASXL2 | 130670 | 3506 | 0.294 | 0.5882 | No | ||
65 | CORT | 360008 2340092 | 3541 | 0.283 | 0.5882 | No | ||
66 | ADAMTS2 | 2650025 6370133 6840670 | 3598 | 0.265 | 0.5869 | No | ||
67 | STAG2 | 4540132 | 3638 | 0.254 | 0.5864 | No | ||
68 | PPP1R8 | 6290292 | 3785 | 0.219 | 0.5798 | No | ||
69 | ERBB2IP | 580253 1090672 | 3909 | 0.196 | 0.5744 | No | ||
70 | POLA2 | 940519 | 4144 | 0.155 | 0.5627 | No | ||
71 | HS6ST3 | 5910138 | 4439 | 0.119 | 0.5476 | No | ||
72 | HNRPD | 4120021 | 4486 | 0.114 | 0.5458 | No | ||
73 | E2F7 | 4200056 | 4524 | 0.111 | 0.5445 | No | ||
74 | FHOD1 | 2680279 | 4555 | 0.108 | 0.5436 | No | ||
75 | TOPBP1 | 6020333 | 4595 | 0.105 | 0.5421 | No | ||
76 | SP3 | 3840338 | 5216 | 0.066 | 0.5090 | No | ||
77 | KCNA6 | 450291 1400086 1660291 2470576 | 5558 | 0.053 | 0.4908 | No | ||
78 | PCSK1 | 2350148 | 5571 | 0.053 | 0.4905 | No | ||
79 | UXT | 110019 5080066 | 5961 | 0.041 | 0.4697 | No | ||
80 | JPH1 | 610739 | 6081 | 0.037 | 0.4635 | No | ||
81 | GRIA4 | 2640131 | 6252 | 0.033 | 0.4545 | No | ||
82 | FMO4 | 360735 | 6310 | 0.031 | 0.4516 | No | ||
83 | ABI2 | 940368 4200092 | 6473 | 0.028 | 0.4430 | No | ||
84 | RHD | 4050168 | 6672 | 0.023 | 0.4324 | No | ||
85 | SLC6A4 | 2230372 | 6727 | 0.022 | 0.4297 | No | ||
86 | SMAD6 | 870504 | 6850 | 0.019 | 0.4232 | No | ||
87 | RQCD1 | 1850139 | 7199 | 0.013 | 0.4044 | No | ||
88 | CRK | 1230162 4780128 | 7694 | 0.004 | 0.3777 | No | ||
89 | STAG1 | 1190300 1400722 4590100 | 7962 | -0.000 | 0.3632 | No | ||
90 | NUP153 | 7000452 | 8186 | -0.004 | 0.3512 | No | ||
91 | FBXO5 | 2630551 | 8235 | -0.005 | 0.3486 | No | ||
92 | ARHGAP6 | 2060121 | 8632 | -0.011 | 0.3272 | No | ||
93 | CBX5 | 3830072 6290167 | 8836 | -0.015 | 0.3163 | No | ||
94 | GABRB3 | 4150164 | 8891 | -0.016 | 0.3135 | No | ||
95 | PRKDC | 1400072 4230541 | 9467 | -0.026 | 0.2825 | No | ||
96 | TREX2 | 4920707 | 9493 | -0.027 | 0.2813 | No | ||
97 | INSM1 | 3450671 | 9698 | -0.030 | 0.2705 | No | ||
98 | PAX6 | 1190025 | 9850 | -0.033 | 0.2625 | No | ||
99 | POLE2 | 6110041 | 9924 | -0.035 | 0.2588 | No | ||
100 | EFNA5 | 460707 2190519 | 10306 | -0.043 | 0.2384 | No | ||
101 | DMD | 1740041 3990332 | 10389 | -0.045 | 0.2343 | No | ||
102 | GPRC5B | 2760114 | 10916 | -0.057 | 0.2061 | No | ||
103 | IPO7 | 2190746 | 10918 | -0.057 | 0.2064 | No | ||
104 | STK35 | 2360121 | 11527 | -0.075 | 0.1740 | No | ||
105 | NRP2 | 4070400 5860041 6650446 | 11605 | -0.077 | 0.1703 | No | ||
106 | PODN | 3710068 | 11862 | -0.087 | 0.1570 | No | ||
107 | MCM2 | 5050139 | 11994 | -0.092 | 0.1505 | No | ||
108 | RAD51 | 6110450 6980280 | 12021 | -0.093 | 0.1497 | No | ||
109 | DNAJC9 | 6130019 | 12121 | -0.098 | 0.1449 | No | ||
110 | EPHB1 | 4610056 | 12404 | -0.113 | 0.1304 | No | ||
111 | MCM8 | 6130743 | 12548 | -0.120 | 0.1234 | No | ||
112 | CASP8AP2 | 5910593 | 12572 | -0.121 | 0.1229 | No | ||
113 | ARID4A | 520156 1050707 | 12750 | -0.134 | 0.1142 | No | ||
114 | HNRPUL1 | 2120008 4920408 5570180 6370609 6770403 | 12896 | -0.143 | 0.1072 | No | ||
115 | HNRPR | 2320440 2900601 4610008 | 13138 | -0.161 | 0.0952 | No | ||
116 | WNT3 | 2360685 | 13290 | -0.173 | 0.0881 | No | ||
117 | PIM1 | 630047 | 13494 | -0.191 | 0.0784 | No | ||
118 | HOXC10 | 5360170 | 13588 | -0.204 | 0.0746 | No | ||
119 | RPS6KA5 | 2120563 7040546 | 13898 | -0.239 | 0.0594 | No | ||
120 | KCND2 | 1170128 2100112 | 13984 | -0.250 | 0.0564 | No | ||
121 | SEMA5A | 6200110 6520435 | 14008 | -0.252 | 0.0567 | No | ||
122 | RANBP1 | 430215 1090180 | 14100 | -0.266 | 0.0535 | No | ||
123 | YBX2 | 3520441 | 14163 | -0.275 | 0.0519 | No | ||
124 | IL4I1 | 3190161 | 14256 | -0.291 | 0.0488 | No | ||
125 | HCN3 | 3940438 6840750 | 14393 | -0.314 | 0.0434 | No | ||
126 | ZBTB4 | 6450441 | 14441 | -0.322 | 0.0429 | No | ||
127 | HMGN2 | 3140091 | 14503 | -0.332 | 0.0417 | No | ||
128 | CCNT1 | 2450563 5390184 | 14574 | -0.345 | 0.0401 | No | ||
129 | ING3 | 110438 2060390 | 14752 | -0.380 | 0.0329 | No | ||
130 | PVRL1 | 2570167 5220519 5890500 3190309 | 14778 | -0.388 | 0.0340 | No | ||
131 | NELL2 | 2340725 4280301 5420008 | 14841 | -0.399 | 0.0332 | No | ||
132 | ATAD2 | 870242 2260687 | 15095 | -0.464 | 0.0225 | No | ||
133 | DDB2 | 3520341 4610168 4850184 4920717 | 15132 | -0.473 | 0.0235 | No | ||
134 | EPC1 | 1570050 5290095 6900193 | 15244 | -0.514 | 0.0208 | No | ||
135 | NUP62 | 1240128 | 15339 | -0.545 | 0.0192 | No | ||
136 | POLR2A | 5220647 | 15341 | -0.546 | 0.0226 | No | ||
137 | PAQR4 | 730736 | 15378 | -0.559 | 0.0242 | No | ||
138 | PHF13 | 450435 | 15487 | -0.599 | 0.0222 | No | ||
139 | HIRA | 4480609 5270167 | 15491 | -0.601 | 0.0258 | No | ||
140 | AP4M1 | 70609 3440128 | 16156 | -0.936 | -0.0042 | No | ||
141 | MRPL40 | 2370215 | 16192 | -0.951 | -0.0000 | No | ||
142 | SFRS10 | 6130528 6400438 7040112 | 16253 | -0.992 | 0.0030 | No | ||
143 | USP52 | 3710215 6380133 | 16385 | -1.057 | 0.0027 | No | ||
144 | RRM2 | 6350059 6940162 | 16418 | -1.075 | 0.0078 | No | ||
145 | ATF5 | 5670685 | 16541 | -1.156 | 0.0085 | No | ||
146 | TYRO3 | 3130193 | 16543 | -1.158 | 0.0158 | No | ||
147 | SFRS2 | 50707 380593 | 16661 | -1.237 | 0.0173 | No | ||
148 | SYNGR4 | 6520450 | 16728 | -1.286 | 0.0219 | No | ||
149 | ACBD6 | 4200446 | 16931 | -1.462 | 0.0203 | No | ||
150 | POLD1 | 4830026 | 17474 | -1.881 | 0.0029 | No | ||
151 | MAZ | 3360121 6940750 | 17643 | -2.048 | 0.0068 | No | ||
152 | UNG | 3130110 6100364 | 17685 | -2.088 | 0.0179 | No | ||
153 | MXD3 | 6220014 | 17737 | -2.166 | 0.0289 | No | ||
154 | HIST1H2BK | 6130433 | 18216 | -2.931 | 0.0217 | No |