Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | -0.442656 |
Normalized Enrichment Score (NES) | -1.2802446 |
Nominal p-value | 0.033167496 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RRAGC | 5910348 | 248 | 3.426 | 0.0161 | No | ||
2 | NEDD4L | 6380368 | 295 | 3.241 | 0.0415 | No | ||
3 | OSR1 | 1500025 | 433 | 2.843 | 0.0586 | No | ||
4 | LNX2 | 3130025 | 957 | 1.945 | 0.0470 | No | ||
5 | GRB2 | 6650398 | 982 | 1.909 | 0.0621 | No | ||
6 | RUNX1 | 3840711 | 1043 | 1.837 | 0.0747 | No | ||
7 | SLC23A2 | 6660722 | 1083 | 1.795 | 0.0881 | No | ||
8 | MFNG | 1770242 4280348 | 1096 | 1.781 | 0.1028 | No | ||
9 | POLR1D | 70082 450750 6040458 | 1287 | 1.565 | 0.1059 | No | ||
10 | EGLN1 | 2480180 3120253 6110195 | 1439 | 1.403 | 0.1098 | No | ||
11 | NUP88 | 2510044 6760180 | 1457 | 1.383 | 0.1208 | No | ||
12 | CORO2B | 2340035 4850390 | 1552 | 1.290 | 0.1269 | No | ||
13 | WNT6 | 4570364 | 1838 | 1.055 | 0.1205 | No | ||
14 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 1975 | 0.978 | 0.1215 | No | ||
15 | KCNN3 | 6520600 6420138 | 2186 | 0.856 | 0.1175 | No | ||
16 | PLAGL2 | 1770148 | 2270 | 0.808 | 0.1200 | No | ||
17 | GRB7 | 2100471 | 2471 | 0.695 | 0.1151 | No | ||
18 | TNFSF13 | 2650170 | 2633 | 0.616 | 0.1117 | No | ||
19 | ADAM12 | 3390132 4070347 | 2820 | 0.531 | 0.1062 | No | ||
20 | RIN1 | 510593 | 2853 | 0.520 | 0.1089 | No | ||
21 | FUT8 | 1340068 2340056 | 2982 | 0.470 | 0.1060 | No | ||
22 | CAMK2A | 1740333 1940112 4150292 | 3090 | 0.428 | 0.1039 | No | ||
23 | SORT1 | 1850242 2320632 3870537 | 3105 | 0.424 | 0.1068 | No | ||
24 | TNFRSF21 | 6380100 | 3281 | 0.363 | 0.1005 | No | ||
25 | SCG2 | 5670438 130671 | 3542 | 0.283 | 0.0888 | No | ||
26 | NTRK3 | 4050687 4070167 4610026 6100484 | 3704 | 0.238 | 0.0821 | No | ||
27 | PIM2 | 840136 5720692 7100577 | 3732 | 0.231 | 0.0827 | No | ||
28 | DSCAM | 1780050 2450731 2810438 | 3921 | 0.193 | 0.0741 | No | ||
29 | HIF3A | 2630053 2680102 6450364 | 3936 | 0.189 | 0.0750 | No | ||
30 | ITGA6 | 3830129 | 3984 | 0.181 | 0.0740 | No | ||
31 | KCNK12 | 4070072 | 4255 | 0.140 | 0.0606 | No | ||
32 | USP2 | 1190292 1240253 4850035 | 4272 | 0.138 | 0.0609 | No | ||
33 | SSH2 | 360056 | 4315 | 0.133 | 0.0598 | No | ||
34 | CXCL14 | 840114 6450324 | 4426 | 0.121 | 0.0548 | No | ||
35 | PCDH15 | 7000438 | 4492 | 0.114 | 0.0523 | No | ||
36 | NFATC4 | 2470735 | 4557 | 0.108 | 0.0497 | No | ||
37 | HR | 2690095 6200300 | 4578 | 0.106 | 0.0496 | No | ||
38 | CANX | 4760402 | 4644 | 0.101 | 0.0469 | No | ||
39 | RAPGEF4 | 6100563 | 4677 | 0.098 | 0.0460 | No | ||
40 | WDR20 | 1240373 | 4719 | 0.095 | 0.0446 | No | ||
41 | FYN | 2100468 4760520 4850687 | 4785 | 0.091 | 0.0419 | No | ||
42 | SIM1 | 1770332 | 4889 | 0.083 | 0.0370 | No | ||
43 | SLC24A3 | 5080707 | 5018 | 0.076 | 0.0307 | No | ||
44 | RAB26 | 5910025 | 5080 | 0.073 | 0.0280 | No | ||
45 | SORCS2 | 6350520 | 5204 | 0.066 | 0.0219 | No | ||
46 | UNC13B | 130735 | 5419 | 0.058 | 0.0108 | No | ||
47 | PACSIN3 | 4540369 4540400 5360037 6940129 | 5445 | 0.057 | 0.0100 | No | ||
48 | GPR37 | 2320093 | 5646 | 0.050 | -0.0004 | No | ||
49 | KCNB1 | 3610035 | 5676 | 0.049 | -0.0016 | No | ||
50 | HSD11B2 | 5900053 | 5786 | 0.045 | -0.0071 | No | ||
51 | SLC12A5 | 1980692 | 6114 | 0.036 | -0.0245 | No | ||
52 | DLL1 | 1770377 | 6175 | 0.035 | -0.0275 | No | ||
53 | CHRND | 840403 2260670 | 6257 | 0.033 | -0.0316 | No | ||
54 | TRIM23 | 580168 6510672 | 6297 | 0.032 | -0.0334 | No | ||
55 | WTAP | 4010176 | 6552 | 0.026 | -0.0470 | No | ||
56 | GATA2 | 6590280 | 6654 | 0.024 | -0.0523 | No | ||
57 | AP1S2 | 780279 4280707 | 6744 | 0.022 | -0.0569 | No | ||
58 | NTRK2 | 6220463 | 6873 | 0.019 | -0.0637 | No | ||
59 | TGFB3 | 1070041 | 6952 | 0.017 | -0.0678 | No | ||
60 | NBL1 | 2480021 | 7094 | 0.015 | -0.0753 | No | ||
61 | CPA4 | 3610100 | 7259 | 0.012 | -0.0841 | No | ||
62 | ASB14 | 5860427 | 7398 | 0.009 | -0.0915 | No | ||
63 | NHLH1 | 6100452 | 7522 | 0.007 | -0.0981 | No | ||
64 | BMP6 | 2100128 | 7647 | 0.005 | -0.1048 | No | ||
65 | SOX17 | 5270551 | 7671 | 0.005 | -0.1060 | No | ||
66 | PPARA | 2060026 | 7862 | 0.001 | -0.1163 | No | ||
67 | CHRDL1 | 1580037 6380204 | 7866 | 0.001 | -0.1164 | No | ||
68 | LAMA5 | 2680722 | 7898 | 0.001 | -0.1181 | No | ||
69 | COL4A4 | 1050541 | 8277 | -0.005 | -0.1385 | No | ||
70 | TCF2 | 870338 5050632 | 8660 | -0.012 | -0.1592 | No | ||
71 | GPM6B | 6220458 | 8670 | -0.012 | -0.1595 | No | ||
72 | ANKRD2 | 6590427 | 8678 | -0.012 | -0.1598 | No | ||
73 | PTPRJ | 4010707 | 9061 | -0.019 | -0.1804 | No | ||
74 | KLHL13 | 6590731 | 9141 | -0.020 | -0.1845 | No | ||
75 | MTSS1 | 780435 2370114 | 9197 | -0.021 | -0.1873 | No | ||
76 | SFTPC | 3290133 | 9209 | -0.021 | -0.1877 | No | ||
77 | DLL3 | 4010093 | 9237 | -0.022 | -0.1890 | No | ||
78 | FOXI1 | 3710095 6620195 | 9244 | -0.022 | -0.1891 | No | ||
79 | GRIA1 | 1340152 3780750 4920440 | 9247 | -0.022 | -0.1890 | No | ||
80 | ARVCF | 2190537 | 9301 | -0.023 | -0.1917 | No | ||
81 | TEAD4 | 1850239 6380519 | 9404 | -0.025 | -0.1970 | No | ||
82 | TREX2 | 4920707 | 9493 | -0.027 | -0.2016 | No | ||
83 | ANK2 | 6510546 | 9507 | -0.027 | -0.2020 | No | ||
84 | GFAP | 2060092 | 9930 | -0.035 | -0.2246 | No | ||
85 | MYOZ3 | 1990138 | 10170 | -0.041 | -0.2372 | No | ||
86 | CPZ | 70193 | 10249 | -0.042 | -0.2411 | No | ||
87 | NR4A1 | 6290161 | 10270 | -0.042 | -0.2418 | No | ||
88 | ARHGEF12 | 3990195 | 10307 | -0.043 | -0.2434 | No | ||
89 | MT3 | 1450537 | 10349 | -0.044 | -0.2453 | No | ||
90 | RTN4RL2 | 6450609 | 10404 | -0.045 | -0.2478 | No | ||
91 | EIF2C1 | 6900551 | 10611 | -0.050 | -0.2585 | No | ||
92 | FGF11 | 840292 | 10619 | -0.050 | -0.2585 | No | ||
93 | NEGR1 | 1940731 5130170 | 10626 | -0.050 | -0.2584 | No | ||
94 | MYH14 | 4010017 | 10795 | -0.055 | -0.2670 | No | ||
95 | ZNF205 | 6900022 | 10903 | -0.057 | -0.2723 | No | ||
96 | DNAJB5 | 2900215 | 11096 | -0.061 | -0.2822 | No | ||
97 | SOST | 1170195 | 11186 | -0.064 | -0.2865 | No | ||
98 | ODC1 | 5670168 | 11202 | -0.064 | -0.2867 | No | ||
99 | GDPD2 | 7000040 | 11260 | -0.066 | -0.2893 | No | ||
100 | NPEPPS | 2630731 | 11303 | -0.068 | -0.2910 | No | ||
101 | DOC2A | 6020121 | 11376 | -0.070 | -0.2943 | No | ||
102 | CCNL2 | 6520167 | 11516 | -0.075 | -0.3012 | No | ||
103 | CHST9 | 4560092 | 11610 | -0.077 | -0.3055 | No | ||
104 | MTUS1 | 780348 4920609 | 11736 | -0.082 | -0.3116 | No | ||
105 | ALDH1A2 | 2320301 | 12024 | -0.093 | -0.3264 | No | ||
106 | NEURL | 5390538 | 12080 | -0.096 | -0.3285 | No | ||
107 | IRX6 | 4590025 | 12081 | -0.096 | -0.3277 | No | ||
108 | CFL1 | 2340735 | 12117 | -0.097 | -0.3288 | No | ||
109 | ROBO3 | 6550408 | 12130 | -0.098 | -0.3286 | No | ||
110 | CALB1 | 460070 | 12350 | -0.110 | -0.3395 | No | ||
111 | CDH5 | 5340487 | 12353 | -0.110 | -0.3387 | No | ||
112 | CALN1 | 3610722 | 12354 | -0.110 | -0.3377 | No | ||
113 | FSCN2 | 1230039 | 12424 | -0.113 | -0.3405 | No | ||
114 | POU2F3 | 2030601 | 12584 | -0.122 | -0.3480 | No | ||
115 | RASSF2 | 2480079 5720546 | 12625 | -0.124 | -0.3491 | No | ||
116 | COL4A3 | 5910075 | 12636 | -0.125 | -0.3486 | No | ||
117 | GGN | 1410528 4210082 5290170 | 12880 | -0.142 | -0.3606 | No | ||
118 | GPD1 | 2480095 | 13040 | -0.154 | -0.3679 | No | ||
119 | PRKAG2 | 2340100 | 13089 | -0.157 | -0.3691 | No | ||
120 | DNMT3A | 4050068 4810717 | 13112 | -0.159 | -0.3689 | No | ||
121 | BRUNOL4 | 4490452 5080451 | 13175 | -0.164 | -0.3709 | No | ||
122 | CYP26A1 | 380022 2690600 | 13255 | -0.170 | -0.3737 | No | ||
123 | MDGA1 | 1170139 | 13340 | -0.177 | -0.3767 | No | ||
124 | NOL4 | 5050446 5360519 | 13567 | -0.201 | -0.3873 | No | ||
125 | ITGB4 | 1740021 3840482 | 14098 | -0.265 | -0.4137 | No | ||
126 | CDH2 | 520435 2450451 2760025 6650477 | 14221 | -0.285 | -0.4179 | No | ||
127 | TNNC2 | 3840079 | 14241 | -0.287 | -0.4164 | No | ||
128 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14274 | -0.293 | -0.4156 | No | ||
129 | PHACTR3 | 3850435 5900445 | 14280 | -0.294 | -0.4134 | No | ||
130 | INVS | 4200632 6620528 | 14305 | -0.298 | -0.4121 | No | ||
131 | EYA3 | 1580195 6510632 | 14363 | -0.309 | -0.4125 | No | ||
132 | HMGN2 | 3140091 | 14503 | -0.332 | -0.4172 | No | ||
133 | LRP5 | 2100397 3170484 | 14514 | -0.333 | -0.4149 | No | ||
134 | SYT4 | 5080193 | 14627 | -0.355 | -0.4179 | No | ||
135 | GJB2 | 5900609 6200487 | 14828 | -0.397 | -0.4253 | No | ||
136 | ACTN3 | 3140541 6480598 | 14918 | -0.418 | -0.4265 | No | ||
137 | HOXB7 | 4540706 4610358 | 14954 | -0.426 | -0.4248 | No | ||
138 | SEMA3F | 5420601 6770731 | 15044 | -0.452 | -0.4257 | No | ||
139 | IGSF8 | 1580592 | 15061 | -0.457 | -0.4226 | No | ||
140 | PLCB3 | 4670402 | 15112 | -0.469 | -0.4213 | No | ||
141 | FGF8 | 6350504 | 15142 | -0.478 | -0.4188 | No | ||
142 | CAMK1D | 1660100 2350309 | 15369 | -0.557 | -0.4262 | No | ||
143 | IGFBP5 | 2360592 | 15673 | -0.674 | -0.4368 | Yes | ||
144 | TPM3 | 670600 3170296 5670167 6650471 | 15740 | -0.702 | -0.4344 | Yes | ||
145 | CORO2A | 3840605 6620390 | 15887 | -0.785 | -0.4355 | Yes | ||
146 | CENTG3 | 2470079 4610092 5050170 | 15963 | -0.825 | -0.4325 | Yes | ||
147 | POFUT1 | 1570458 | 16068 | -0.877 | -0.4306 | Yes | ||
148 | IGF2 | 6510020 | 16119 | -0.911 | -0.4254 | Yes | ||
149 | LRP10 | 1580128 | 16173 | -0.944 | -0.4202 | Yes | ||
150 | ARHGAP24 | 540278 4540025 | 16237 | -0.981 | -0.4151 | Yes | ||
151 | STC2 | 4920601 | 16312 | -1.019 | -0.4104 | Yes | ||
152 | CNNM2 | 2650100 | 16454 | -1.096 | -0.4086 | Yes | ||
153 | TNFAIP1 | 6940593 | 16540 | -1.154 | -0.4032 | Yes | ||
154 | RANGAP1 | 2320593 6650601 | 16567 | -1.171 | -0.3945 | Yes | ||
155 | CENTB1 | 2120093 | 16633 | -1.219 | -0.3876 | Yes | ||
156 | SIPA1 | 5220687 | 17003 | -1.500 | -0.3946 | Yes | ||
157 | CKM | 1450524 | 17033 | -1.513 | -0.3832 | Yes | ||
158 | TTC17 | 2470440 | 17090 | -1.553 | -0.3728 | Yes | ||
159 | CRELD1 | 2060253 | 17295 | -1.721 | -0.3691 | Yes | ||
160 | SMAD3 | 6450671 | 17349 | -1.764 | -0.3567 | Yes | ||
161 | GNAS | 630441 1850373 4050152 | 17359 | -1.771 | -0.3420 | Yes | ||
162 | HES6 | 540411 6550504 | 17666 | -2.067 | -0.3407 | Yes | ||
163 | PSTPIP1 | 3190156 | 17706 | -2.121 | -0.3246 | Yes | ||
164 | SASH1 | 4070270 | 17723 | -2.147 | -0.3069 | Yes | ||
165 | SELL | 1190500 | 17775 | -2.211 | -0.2907 | Yes | ||
166 | PPOX | 2640678 3850102 | 17956 | -2.473 | -0.2791 | Yes | ||
167 | PPP1R9B | 3130619 | 18017 | -2.558 | -0.2603 | Yes | ||
168 | SLC37A4 | 6400079 | 18057 | -2.633 | -0.2397 | Yes | ||
169 | DEF6 | 840593 | 18062 | -2.636 | -0.2172 | Yes | ||
170 | ARID5A | 2450133 | 18127 | -2.734 | -0.1972 | Yes | ||
171 | GFRA1 | 3610152 | 18180 | -2.845 | -0.1755 | Yes | ||
172 | ELOVL1 | 2450019 4760138 5340685 | 18348 | -3.294 | -0.1561 | Yes | ||
173 | ENO3 | 5270136 | 18352 | -3.305 | -0.1278 | Yes | ||
174 | PTK2B | 4730411 | 18400 | -3.448 | -0.1006 | Yes | ||
175 | AIG1 | 2450091 | 18526 | -4.174 | -0.0715 | Yes | ||
176 | HEYL | 5860528 | 18543 | -4.355 | -0.0348 | Yes | ||
177 | HMGA1 | 6580408 | 18552 | -4.491 | 0.0035 | Yes |