Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$BACH1_01 |
Enrichment Score (ES) | -0.42112678 |
Normalized Enrichment Score (NES) | -1.2272469 |
Nominal p-value | 0.057096247 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | H3F3B | 1410300 | 42 | 4.822 | 0.0277 | No | ||
2 | SRPK2 | 6380341 | 87 | 4.282 | 0.0519 | No | ||
3 | PPP2CA | 3990113 | 115 | 4.067 | 0.0757 | No | ||
4 | LUC7L | 6040156 6110411 | 322 | 3.137 | 0.0840 | No | ||
5 | BRD2 | 1450300 5340484 6100605 | 396 | 2.955 | 0.0984 | No | ||
6 | TRIM8 | 6130441 | 453 | 2.806 | 0.1128 | No | ||
7 | ATP1B1 | 3130594 | 478 | 2.762 | 0.1287 | No | ||
8 | EIF4G1 | 4070446 | 496 | 2.717 | 0.1446 | No | ||
9 | NR1D1 | 2360471 770746 6590204 | 602 | 2.480 | 0.1544 | No | ||
10 | PSMD7 | 2030619 6220594 | 697 | 2.328 | 0.1637 | No | ||
11 | RPL23A | 1450403 | 766 | 2.220 | 0.1738 | No | ||
12 | CHST1 | 50601 | 895 | 2.056 | 0.1797 | No | ||
13 | PSMD12 | 730044 | 1178 | 1.690 | 0.1749 | No | ||
14 | RBBP7 | 430113 450450 2370309 | 1507 | 1.334 | 0.1653 | No | ||
15 | EMP3 | 1500722 1570039 | 1548 | 1.293 | 0.1712 | No | ||
16 | MECP2 | 1940450 | 1803 | 1.075 | 0.1641 | No | ||
17 | BTK | 3130044 | 1814 | 1.068 | 0.1702 | No | ||
18 | SGK | 1400131 2480056 | 1900 | 1.013 | 0.1719 | No | ||
19 | TRAF3 | 5690647 | 2043 | 0.943 | 0.1700 | No | ||
20 | LAMC1 | 4730025 | 2095 | 0.908 | 0.1729 | No | ||
21 | GTF2B | 6860685 | 2263 | 0.810 | 0.1689 | No | ||
22 | APOBEC1 | 4610022 | 2287 | 0.801 | 0.1726 | No | ||
23 | GPX1 | 4150093 | 2345 | 0.768 | 0.1743 | No | ||
24 | DYRK1A | 3190181 | 2353 | 0.763 | 0.1786 | No | ||
25 | ACADVL | 6040403 | 2359 | 0.760 | 0.1831 | No | ||
26 | TNRC15 | 6760746 | 2526 | 0.662 | 0.1782 | No | ||
27 | GTPBP2 | 2760750 | 2630 | 0.618 | 0.1765 | No | ||
28 | RAB34 | 770411 | 2808 | 0.537 | 0.1702 | No | ||
29 | RIN1 | 510593 | 2853 | 0.520 | 0.1710 | No | ||
30 | MAST2 | 6200348 | 2905 | 0.496 | 0.1714 | No | ||
31 | PSMD4 | 430068 | 2925 | 0.488 | 0.1734 | No | ||
32 | SEC24D | 3060279 | 3003 | 0.462 | 0.1720 | No | ||
33 | ABI3 | 1740563 | 3038 | 0.448 | 0.1730 | No | ||
34 | MPV17 | 1190133 4070427 4570577 | 3290 | 0.358 | 0.1616 | No | ||
35 | NLK | 2030010 2450041 | 3499 | 0.295 | 0.1521 | No | ||
36 | EN1 | 5360168 7050025 | 3547 | 0.281 | 0.1513 | No | ||
37 | EIF4E | 1580403 70133 6380215 | 3604 | 0.264 | 0.1499 | No | ||
38 | CDKN1A | 4050088 6400706 | 3730 | 0.231 | 0.1446 | No | ||
39 | CAPN12 | 2100050 | 3751 | 0.227 | 0.1449 | No | ||
40 | NEK6 | 3360687 | 3818 | 0.213 | 0.1427 | No | ||
41 | AXUD1 | 1230053 | 3852 | 0.207 | 0.1422 | No | ||
42 | LAMA3 | 1190131 5290239 | 3969 | 0.184 | 0.1370 | No | ||
43 | RGS2 | 1090736 | 3979 | 0.182 | 0.1376 | No | ||
44 | IBRDC2 | 5130041 | 4167 | 0.152 | 0.1284 | No | ||
45 | ADAMTSL1 | 2970092 | 4192 | 0.148 | 0.1281 | No | ||
46 | SSH2 | 360056 | 4315 | 0.133 | 0.1223 | No | ||
47 | NRAS | 6900577 | 4328 | 0.132 | 0.1224 | No | ||
48 | WASF2 | 4850592 | 4480 | 0.115 | 0.1149 | No | ||
49 | MARK1 | 450484 | 4561 | 0.108 | 0.1113 | No | ||
50 | KCNA2 | 5080403 | 4589 | 0.105 | 0.1105 | No | ||
51 | LAMC2 | 450692 2680041 4200059 4670148 | 4629 | 0.102 | 0.1090 | No | ||
52 | AKT3 | 1580270 3290278 | 4634 | 0.102 | 0.1094 | No | ||
53 | MMP3 | 2650368 2970056 | 4701 | 0.096 | 0.1064 | No | ||
54 | SLC26A1 | 2190142 | 5043 | 0.075 | 0.0884 | No | ||
55 | GNAI1 | 4560390 | 5227 | 0.065 | 0.0789 | No | ||
56 | SPARC | 1690086 | 5355 | 0.060 | 0.0723 | No | ||
57 | SNCB | 3360133 | 5427 | 0.057 | 0.0688 | No | ||
58 | AKAP1 | 110148 1740735 2260019 7000563 | 5552 | 0.053 | 0.0624 | No | ||
59 | SYNGR1 | 5130452 6650056 | 5737 | 0.047 | 0.0528 | No | ||
60 | MAMDC2 | 430471 | 5926 | 0.041 | 0.0428 | No | ||
61 | MYB | 1660494 5860451 6130706 | 6007 | 0.039 | 0.0387 | No | ||
62 | TRIM47 | 5080717 | 6228 | 0.033 | 0.0270 | No | ||
63 | FAP | 4560019 | 6354 | 0.030 | 0.0204 | No | ||
64 | LAMB3 | 7100301 | 6691 | 0.023 | 0.0023 | No | ||
65 | UCN2 | 4590372 | 6699 | 0.023 | 0.0021 | No | ||
66 | SLC6A5 | 870121 | 7189 | 0.013 | -0.0244 | No | ||
67 | SH3RF2 | 6200600 | 7207 | 0.013 | -0.0252 | No | ||
68 | CFL2 | 380239 6200368 | 7413 | 0.009 | -0.0363 | No | ||
69 | NR1I3 | 50026 1240673 | 7506 | 0.007 | -0.0413 | No | ||
70 | IL11 | 1740398 | 7736 | 0.003 | -0.0537 | No | ||
71 | PHLDA2 | 4810494 | 8009 | -0.001 | -0.0684 | No | ||
72 | IL1RN | 2370333 | 8021 | -0.001 | -0.0690 | No | ||
73 | SHC3 | 2690398 | 8135 | -0.003 | -0.0751 | No | ||
74 | BNIP3 | 3140270 | 8199 | -0.004 | -0.0785 | No | ||
75 | SYT2 | 60609 | 8773 | -0.014 | -0.1095 | No | ||
76 | ENO2 | 2320068 | 8820 | -0.015 | -0.1119 | No | ||
77 | TNXB | 630592 3830020 5360497 7000673 | 8948 | -0.017 | -0.1187 | No | ||
78 | TREX1 | 3450040 7100692 | 9111 | -0.020 | -0.1274 | No | ||
79 | GRIA1 | 1340152 3780750 4920440 | 9247 | -0.022 | -0.1346 | No | ||
80 | MYBPH | 2190711 | 9266 | -0.022 | -0.1354 | No | ||
81 | CSF3 | 2230193 6660707 | 9275 | -0.022 | -0.1357 | No | ||
82 | PSMD11 | 2340538 6510053 | 9447 | -0.025 | -0.1448 | No | ||
83 | P2RXL1 | 4730390 5220446 | 9477 | -0.026 | -0.1462 | No | ||
84 | DSC2 | 840484 | 9595 | -0.028 | -0.1524 | No | ||
85 | FADS3 | 3120079 | 9668 | -0.030 | -0.1561 | No | ||
86 | NTN4 | 6940398 | 9751 | -0.031 | -0.1604 | No | ||
87 | GPR56 | 1190494 | 9821 | -0.033 | -0.1639 | No | ||
88 | FOXA1 | 3710609 | 9825 | -0.033 | -0.1639 | No | ||
89 | LPP | 1660541 | 9890 | -0.034 | -0.1671 | No | ||
90 | GFAP | 2060092 | 9930 | -0.035 | -0.1690 | No | ||
91 | TIAL1 | 4150048 6510605 | 9953 | -0.036 | -0.1700 | No | ||
92 | SLC24A4 | 2100487 | 9963 | -0.036 | -0.1703 | No | ||
93 | TAC1 | 7000195 380706 | 9984 | -0.037 | -0.1711 | No | ||
94 | FABP4 | 5050114 | 10118 | -0.039 | -0.1781 | No | ||
95 | LY6G6C | 6020673 | 10378 | -0.045 | -0.1919 | No | ||
96 | ELK3 | 460377 1400762 3710497 | 10471 | -0.047 | -0.1966 | No | ||
97 | COL7A1 | 1230168 2190072 | 10730 | -0.053 | -0.2103 | No | ||
98 | DNAJC5B | 60368 | 10778 | -0.054 | -0.2125 | No | ||
99 | MYH14 | 4010017 | 10795 | -0.055 | -0.2130 | No | ||
100 | EIF3S1 | 6130368 6770044 | 10825 | -0.055 | -0.2142 | No | ||
101 | TGM3 | 840576 | 10886 | -0.056 | -0.2171 | No | ||
102 | FOXN1 | 4730075 | 10912 | -0.057 | -0.2181 | No | ||
103 | CAPN6 | 1740168 | 10923 | -0.057 | -0.2183 | No | ||
104 | TRIB1 | 2320435 | 10969 | -0.058 | -0.2204 | No | ||
105 | LRRTM3 | 4210021 | 11035 | -0.060 | -0.2236 | No | ||
106 | FGF12 | 1740446 2360037 | 11185 | -0.064 | -0.2313 | No | ||
107 | GPR3 | 2970452 | 11609 | -0.077 | -0.2537 | No | ||
108 | TLL1 | 2680315 | 11696 | -0.081 | -0.2579 | No | ||
109 | VIT | 6620301 | 11759 | -0.083 | -0.2607 | No | ||
110 | GDNF | 4050487 5720739 | 12045 | -0.094 | -0.2756 | No | ||
111 | LRRC15 | 3940609 | 12076 | -0.096 | -0.2767 | No | ||
112 | BMP2 | 6620687 | 12259 | -0.104 | -0.2859 | No | ||
113 | SYP | 2690168 | 12371 | -0.111 | -0.2912 | No | ||
114 | PSME4 | 380348 1770131 | 12656 | -0.126 | -0.3059 | No | ||
115 | EEF1A2 | 2260162 5290086 | 12751 | -0.134 | -0.3101 | No | ||
116 | OSBP | 5390471 | 12793 | -0.136 | -0.3115 | No | ||
117 | SYN1 | 4920301 7050440 | 12842 | -0.139 | -0.3132 | No | ||
118 | DIRAS1 | 2640270 | 12992 | -0.150 | -0.3204 | No | ||
119 | ELAVL2 | 360181 | 13114 | -0.159 | -0.3260 | No | ||
120 | HS3ST3B1 | 380040 | 13244 | -0.169 | -0.3319 | No | ||
121 | F2RL2 | 6110736 | 13263 | -0.170 | -0.3318 | No | ||
122 | GKN1 | 5420091 | 13355 | -0.178 | -0.3357 | No | ||
123 | PADI3 | 6520072 | 13367 | -0.179 | -0.3352 | No | ||
124 | PIM1 | 630047 | 13494 | -0.191 | -0.3408 | No | ||
125 | CSMD3 | 1660427 1940687 | 13606 | -0.206 | -0.3456 | No | ||
126 | HOXB3 | 520292 | 13852 | -0.234 | -0.3574 | No | ||
127 | PROK2 | 540538 | 13861 | -0.235 | -0.3564 | No | ||
128 | ITGB4 | 1740021 3840482 | 14098 | -0.265 | -0.3675 | No | ||
129 | DYSF | 4670411 | 14140 | -0.272 | -0.3681 | No | ||
130 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14274 | -0.293 | -0.3735 | No | ||
131 | RB1CC1 | 510494 7100072 | 14304 | -0.298 | -0.3732 | No | ||
132 | HCN3 | 3940438 6840750 | 14393 | -0.314 | -0.3760 | No | ||
133 | RPS20 | 1740092 | 14431 | -0.320 | -0.3760 | No | ||
134 | SLC26A9 | 3440722 5340088 7510093 | 14460 | -0.324 | -0.3755 | No | ||
135 | MRGPRF | 4780746 | 14552 | -0.341 | -0.3784 | No | ||
136 | PTPRR | 130121 3990273 | 14677 | -0.365 | -0.3828 | No | ||
137 | PRX | 2260400 4200347 | 14681 | -0.365 | -0.3807 | No | ||
138 | TUBB4 | 5310681 | 14819 | -0.395 | -0.3857 | No | ||
139 | ELL | 3520731 | 14909 | -0.416 | -0.3879 | No | ||
140 | BDKRB1 | 730592 | 15174 | -0.490 | -0.3992 | No | ||
141 | ADRA1A | 1230446 2260390 | 15217 | -0.507 | -0.3983 | No | ||
142 | S100A10 | 6350010 | 15227 | -0.509 | -0.3957 | No | ||
143 | RTN4 | 50725 630647 870097 870184 | 15236 | -0.512 | -0.3929 | No | ||
144 | ACPP | 2470152 1780593 2690524 | 15294 | -0.530 | -0.3927 | No | ||
145 | CDH23 | 4250242 5290397 6550397 | 15403 | -0.570 | -0.3950 | No | ||
146 | GABARAPL1 | 2810458 | 15682 | -0.678 | -0.4059 | No | ||
147 | SCRN1 | 6040025 6580019 | 15889 | -0.786 | -0.4122 | No | ||
148 | DDIT3 | 780373 | 15909 | -0.796 | -0.4083 | No | ||
149 | EEF1A1 | 1980193 1990195 4670735 | 15982 | -0.835 | -0.4070 | No | ||
150 | MNT | 4920575 | 16243 | -0.985 | -0.4150 | Yes | ||
151 | UBE2E3 | 2030347 3840471 | 16263 | -0.996 | -0.4098 | Yes | ||
152 | PADI4 | 1740075 4810441 | 16280 | -1.002 | -0.4045 | Yes | ||
153 | NDRG2 | 450403 | 16341 | -1.032 | -0.4013 | Yes | ||
154 | EPHB2 | 1090288 1410377 2100541 | 16370 | -1.047 | -0.3963 | Yes | ||
155 | AP2A2 | 130082 | 16438 | -1.086 | -0.3932 | Yes | ||
156 | HSPB8 | 540563 | 16555 | -1.166 | -0.3923 | Yes | ||
157 | SFRS2 | 50707 380593 | 16661 | -1.237 | -0.3903 | Yes | ||
158 | ECM1 | 940068 5390309 | 16804 | -1.342 | -0.3897 | Yes | ||
159 | SERTAD1 | 2680332 | 16811 | -1.348 | -0.3816 | Yes | ||
160 | ABHD4 | 6760450 | 16929 | -1.462 | -0.3789 | Yes | ||
161 | LTB4R2 | 1990746 | 17063 | -1.532 | -0.3766 | Yes | ||
162 | BAG2 | 2900324 | 17077 | -1.540 | -0.3677 | Yes | ||
163 | TAGLN2 | 4560121 | 17183 | -1.619 | -0.3633 | Yes | ||
164 | DCTN2 | 540471 3780717 | 17212 | -1.640 | -0.3547 | Yes | ||
165 | TNFRSF12A | 4810253 | 17287 | -1.716 | -0.3480 | Yes | ||
166 | UBE2C | 6130017 | 17457 | -1.873 | -0.3456 | Yes | ||
167 | SNPH | 2680484 | 17488 | -1.890 | -0.3354 | Yes | ||
168 | NCDN | 50040 1980739 3520603 | 17519 | -1.916 | -0.3252 | Yes | ||
169 | ADCK4 | 1660180 | 17583 | -1.985 | -0.3162 | Yes | ||
170 | ROM1 | 3130685 | 17638 | -2.044 | -0.3065 | Yes | ||
171 | PKP3 | 3710048 | 17669 | -2.072 | -0.2952 | Yes | ||
172 | RAB3D | 4210253 | 17701 | -2.109 | -0.2838 | Yes | ||
173 | SQSTM1 | 6550056 | 17732 | -2.162 | -0.2720 | Yes | ||
174 | CAMKK1 | 6370324 | 17832 | -2.283 | -0.2632 | Yes | ||
175 | HDAC3 | 4060072 | 17839 | -2.296 | -0.2492 | Yes | ||
176 | ENO1 | 5340128 | 17995 | -2.530 | -0.2419 | Yes | ||
177 | PPP1R9B | 3130619 | 18017 | -2.558 | -0.2272 | Yes | ||
178 | LMNA | 520471 1500075 3190167 4210020 | 18022 | -2.565 | -0.2115 | Yes | ||
179 | RPS6KA4 | 2190524 | 18080 | -2.652 | -0.1981 | Yes | ||
180 | TRAPPC3 | 2030176 6020609 6590373 6760019 | 18085 | -2.656 | -0.1818 | Yes | ||
181 | ITPKC | 5420021 | 18099 | -2.678 | -0.1658 | Yes | ||
182 | ABCA2 | 5050039 | 18231 | -2.965 | -0.1545 | Yes | ||
183 | ALS2CR2 | 6450128 7100092 | 18261 | -3.052 | -0.1371 | Yes | ||
184 | BCL9L | 6940053 | 18318 | -3.207 | -0.1203 | Yes | ||
185 | ABCD1 | 5670373 | 18368 | -3.366 | -0.1020 | Yes | ||
186 | EDG5 | 2640300 | 18466 | -3.760 | -0.0839 | Yes | ||
187 | HMGA1 | 6580408 | 18552 | -4.491 | -0.0606 | Yes | ||
188 | GNGT2 | 540176 | 18566 | -4.702 | -0.0321 | Yes | ||
189 | ALDOA | 6290672 | 18596 | -5.593 | 0.0011 | Yes |