Details for gene set V$AREB6

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos
Phenotype	phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos
Upregulated in class	truncNotch
GeneSet	V$AREB6_03
Enrichment Score (ES)	-0.4093947
Normalized Enrichment Score (NES)	-1.1912892
Nominal p-value	0.09803922
FDR q-value	1.0
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CXCR4	4590519	174	3.739	0.0270	No
2	PPP1R16B	3520300	423	2.877	0.0416	No
3	NCOR1	3710132	435	2.842	0.0688	No
4	MAPK14	5290731	1140	1.736	0.0475	No
5	SLC7A11	2850138	1215	1.655	0.0597	No
6	CACNB3	2480035 4540184	1363	1.487	0.0662	No
7	ROCK1	130044	1410	1.431	0.0777	No
8	E2F1	5360093	1556	1.284	0.0823	No
9	NRF1	2650195	1636	1.212	0.0898	No
10	APP	2510053	1689	1.158	0.0983	No
11	VGLL4	6860463	1755	1.106	0.1056	No
12	BCL7A	4560095	1808	1.071	0.1132	No
13	SFRS7	2760408	1858	1.040	0.1207	No
14	SLC16A6	1690156	1865	1.035	0.1305	No
15	ELMO1	110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180	1975	0.978	0.1341	No
16	THRA	6770341 110164 1990600	2080	0.916	0.1374	No
17	H2AFY	4730750	2222	0.836	0.1379	No
18	PLAGL2	1770148	2270	0.808	0.1432	No
19	MYH10	2640673	2426	0.718	0.1418	No
20	TACC2	580092 1400364 2650497 2690315 5360338	2813	0.535	0.1261	No
21	ADAM12	3390132 4070347	2820	0.531	0.1310	No
22	FLNB	2510575	2861	0.516	0.1338	No
23	NR4A2	60273	2891	0.502	0.1372	No
24	FUT8	1340068 2340056	2982	0.470	0.1369	No
25	EXTL3	540309 3130215 5860500	3231	0.381	0.1271	No
26	FAF1	2450717 2510121 4730156	3435	0.315	0.1192	No
27	NTRK3	4050687 4070167 4610026 6100484	3704	0.238	0.1070	No
28	PIM2	840136 5720692 7100577	3732	0.231	0.1078	No
29	DSCAM	1780050 2450731 2810438	3921	0.193	0.0995	No
30	ITGA6	3830129	3984	0.181	0.0979	No
31	FST	1110600	4120	0.158	0.0921	No
32	JUB	5860711 5900500	4590	0.105	0.0677	No
33	LAMC2	450692 2680041 4200059 4670148	4629	0.102	0.0666	No
34	RPS6KB1	1450427 5080110 6200563	4657	0.099	0.0661	No
35	MESDC1	2030019	4662	0.099	0.0669	No
36	CRMP1	4810014	4800	0.090	0.0603	No
37	PFTK1	1780181	4849	0.086	0.0586	No
38	LYL1	2900242	4867	0.084	0.0585	No
39	FBXO24	1230132 4610121	4999	0.076	0.0521	No
40	SNAP25	360520	5010	0.076	0.0523	No
41	SLC24A3	5080707	5018	0.076	0.0527	No
42	SSX2IP	4610176	5044	0.075	0.0520	No
43	CCKAR	4210079	5046	0.074	0.0527	No
44	SDPR	3360292	5065	0.073	0.0525	No
45	PDE1C	3940600	5173	0.068	0.0473	No
46	CRB3	6940091	5305	0.062	0.0408	No
47	PLCB2	360132	5506	0.055	0.0305	No
48	MAB21L1	1450634 1580092	5811	0.045	0.0145	No
49	POU4F2	2120195 2570022	5886	0.042	0.0109	No
50	EDG2	6290215	6059	0.038	0.0019	No
51	CHX10	3830184	6084	0.037	0.0010	No
52	CEL	2640278	6135	0.036	-0.0014	No
53	EDG1	4200619	6152	0.035	-0.0019	No
54	ARTN	360670 1170333 1500520	6244	0.033	-0.0065	No
55	HCRTR1	1580273	6553	0.026	-0.0229	No
56	PDGFA	6020095	6709	0.022	-0.0311	No
57	AP1S2	780279 4280707	6744	0.022	-0.0328	No
58	NGFB	2630019	6981	0.017	-0.0454	No
59	USP15	610592 3520504	7236	0.012	-0.0590	No
60	ZNF462	6900100	7439	0.009	-0.0699	No
61	DSTN	3140592	7472	0.008	-0.0716	No
62	KLHL1	6350021	7508	0.007	-0.0734	No
63	TACSTD1	3780025	7821	0.002	-0.0903	No
64	GPR126	6650204	7925	0.000	-0.0958	No
65	CHRNB1	1190671	7942	-0.000	-0.0967	No
66	DIO2	380504 540403	8286	-0.006	-0.1153	No
67	MMP16	2680139	8350	-0.007	-0.1186	No
68	HOXA11	6980133	8363	-0.007	-0.1192	No
69	ELL3	1770484	8392	-0.008	-0.1206	No
70	TCF2	870338 5050632	8660	-0.012	-0.1350	No
71	SYT2	60609	8773	-0.014	-0.1409	No
72	JAG1	3440390	8849	-0.015	-0.1448	No
73	SLC9A7	5360301	9075	-0.019	-0.1568	No
74	DNMT3B	2320138 4070059	9086	-0.019	-0.1572	No
75	TLX2	1090128 2900451	9352	-0.024	-0.1713	No
76	NGFR	3140102	9625	-0.029	-0.1858	No
77	CBX8	50671	9809	-0.033	-0.1954	No
78	FOXA1	3710609	9825	-0.033	-0.1959	No
79	EYA1	1450278 5220390	9835	-0.033	-0.1960	No
80	CHRM1	4280619	10176	-0.041	-0.2141	No
81	TECTA	2570372	10213	-0.041	-0.2156	No
82	KHDRBS2	3520717	10252	-0.042	-0.2173	No
83	DMD	1740041 3990332	10389	-0.045	-0.2242	No
84	IL17C	5690347	10814	-0.055	-0.2467	No
85	DDAH1	6400750	10890	-0.056	-0.2502	No
86	ACTA1	840538	11083	-0.061	-0.2600	No
87	SCNN1G	520600	11171	-0.063	-0.2641	No
88	CDH3	5390112 6860603	11279	-0.067	-0.2692	No
89	NPEPPS	2630731	11303	-0.068	-0.2698	No
90	POU4F1	2260315	11335	-0.069	-0.2708	No
91	SLC30A3	1850451	11371	-0.070	-0.2720	No
92	DOC2A	6020121	11376	-0.070	-0.2716	No
93	ERBB3	5890372	11431	-0.072	-0.2738	No
94	FGF9	1050195	11581	-0.077	-0.2811	No
95	JMJD1C	940575 2120025	11594	-0.077	-0.2810	No
96	MTUS1	780348 4920609	11736	-0.082	-0.2879	No
97	DSCAML1	1850403 5550079	11945	-0.090	-0.2983	No
98	PNOC	1990114	11991	-0.092	-0.2998	No
99	PVRL4	2340048 6220195	11998	-0.092	-0.2992	No
100	TNNT3	1570239	12629	-0.124	-0.3322	No
101	AHR	4560671	12673	-0.128	-0.3333	No
102	SSBP4	2570735	12907	-0.144	-0.3445	No
103	DGKA	5720152 5890328	12976	-0.149	-0.3467	No
104	SSH3	6290110 6650497	13000	-0.151	-0.3465	No
105	GPD1	2480095	13040	-0.154	-0.3471	No
106	DNMT3A	4050068 4810717	13112	-0.159	-0.3494	No
107	SCUBE2	2850315 5130040	13113	-0.159	-0.3478	No
108	CD2AP	1940369	13118	-0.159	-0.3465	No
109	LRRN1	3290154	13177	-0.164	-0.3481	No
110	SCN3B	840112 1780152 5910685 6100131	13209	-0.166	-0.3481	No
111	KCNJ11	2510131	13250	-0.169	-0.3486	No
112	IL4	6020537	13337	-0.177	-0.3516	No
113	LRCH4	5220279 6510026	13396	-0.181	-0.3529	No
114	DSG2	360528 2630603	13884	-0.237	-0.3770	No
115	ITGB4	1740021 3840482	14098	-0.265	-0.3860	No
116	SMTN	670563 1190438	14154	-0.275	-0.3863	No
117	FA2H	730672	14196	-0.280	-0.3858	No
118	LIMK2	2650446 4050164	14229	-0.286	-0.3847	No
119	PHACTR3	3850435 5900445	14280	-0.294	-0.3846	No
120	LSP1	2350091	14356	-0.307	-0.3856	No
121	IRF6	840241 2640139 4050373 6840471	14408	-0.317	-0.3853	No
122	LRP5	2100397 3170484	14514	-0.333	-0.3878	No
123	KIF1C	2480484	14556	-0.341	-0.3866	No
124	KREMEN2	110025	14703	-0.372	-0.3909	No
125	PPP1R14C	2570692 5290204 6420184	14807	-0.393	-0.3927	No
126	SEMA3F	5420601 6770731	15044	-0.452	-0.4011	No
127	FGF8	6350504	15142	-0.478	-0.4017	No
128	ACCN4	6380551	15266	-0.522	-0.4032	No
129	NUMBL	6130360 6200333	15326	-0.542	-0.4012	No
130	SH2D3C	3060014	15479	-0.597	-0.4036	Yes
131	MLLT3	510204 3850722 6200088	15492	-0.601	-0.3984	Yes
132	GNG8	4920358	15506	-0.604	-0.3932	Yes
133	MRPL14	2370168	15537	-0.617	-0.3888	Yes
134	ALX3	50497	15624	-0.651	-0.3871	Yes
135	MKL1	6840161	15710	-0.691	-0.3850	Yes
136	CAMTA2	3990075	15753	-0.710	-0.3803	Yes
137	WDR5	4150736	15820	-0.747	-0.3766	Yes
138	HNF4A	6620440	15829	-0.753	-0.3697	Yes
139	PHF1	4010577 6420053	15912	-0.798	-0.3664	Yes
140	POFUT1	1570458	16068	-0.877	-0.3662	Yes
141	IGF2	6510020	16119	-0.911	-0.3601	Yes
142	L3MBTL2	6020341	16197	-0.956	-0.3549	Yes
143	SEMA4G	5890026	16294	-1.010	-0.3503	Yes
144	TEC	1400576	16327	-1.025	-0.3420	Yes
145	PDE11A	2190215	16533	-1.150	-0.3419	Yes
146	SERF2	5720010	16563	-1.169	-0.3321	Yes
147	REPIN1	6110400	16770	-1.319	-0.3304	Yes
148	RGMA	2450711	16803	-1.342	-0.3190	Yes
149	PARD6A	4120170	16832	-1.374	-0.3071	Yes
150	TNNI1	3710040	16836	-1.380	-0.2939	Yes
151	CIZ1	4150128 6130484	16869	-1.413	-0.2818	Yes
152	FXC1	3710053 4060575	16986	-1.491	-0.2736	Yes
153	SSBP3	870717 1050377 7040551	17013	-1.506	-0.2603	Yes
154	CRELD1	2060253	17295	-1.721	-0.2587	Yes
155	VAT1	1050040	17308	-1.732	-0.2425	Yes
156	NFE2	3710373	17535	-1.936	-0.2359	Yes
157	CRSP7	4230408	17602	-2.007	-0.2199	Yes
158	EHD1	3840731	17612	-2.017	-0.2007	Yes
159	DGKZ	3460041 6400129	17689	-2.098	-0.1844	Yes
160	HDAC3	4060072	17839	-2.296	-0.1701	Yes
161	GNA12	1230301	17925	-2.428	-0.1510	Yes
162	WDR6	7050154	18004	-2.543	-0.1304	Yes
163	CUEDC1	1660463	18053	-2.628	-0.1074	Yes
164	ARFIP2	1850301 4670180	18224	-2.947	-0.0879	Yes
165	ALS2CR2	6450128 7100092	18261	-3.052	-0.0601	Yes
166	FGR	3780047	18321	-3.215	-0.0319	Yes
167	PNKP	4610685 5720605	18578	-4.908	0.0021	Yes