Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$AP1_01 |
Enrichment Score (ES) | -0.41521576 |
Normalized Enrichment Score (NES) | -1.2137936 |
Nominal p-value | 0.06902357 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PPP2CA | 3990113 | 115 | 4.067 | 0.0217 | No | ||
2 | VAPA | 2480594 | 136 | 3.924 | 0.0475 | No | ||
3 | NEDD4L | 6380368 | 295 | 3.241 | 0.0611 | No | ||
4 | LUC7L | 6040156 6110411 | 322 | 3.137 | 0.0813 | No | ||
5 | ATP1B1 | 3130594 | 478 | 2.762 | 0.0918 | No | ||
6 | ICK | 1580746 3140021 | 568 | 2.543 | 0.1044 | No | ||
7 | PSMD7 | 2030619 6220594 | 697 | 2.328 | 0.1134 | No | ||
8 | VCL | 4120487 | 901 | 2.044 | 0.1164 | No | ||
9 | SNX10 | 3800035 | 1170 | 1.695 | 0.1135 | No | ||
10 | PSMD12 | 730044 | 1178 | 1.690 | 0.1247 | No | ||
11 | MAPK10 | 6110193 | 1247 | 1.612 | 0.1321 | No | ||
12 | HSD3B7 | 1410129 | 1490 | 1.356 | 0.1283 | No | ||
13 | RBBP7 | 430113 450450 2370309 | 1507 | 1.334 | 0.1365 | No | ||
14 | EMP3 | 1500722 1570039 | 1548 | 1.293 | 0.1432 | No | ||
15 | YWHAG | 3780341 | 1591 | 1.251 | 0.1495 | No | ||
16 | GADD45G | 2510142 | 1766 | 1.097 | 0.1476 | No | ||
17 | MECP2 | 1940450 | 1803 | 1.075 | 0.1530 | No | ||
18 | BTK | 3130044 | 1814 | 1.068 | 0.1598 | No | ||
19 | TRAF3 | 5690647 | 2043 | 0.943 | 0.1539 | No | ||
20 | LAMC1 | 4730025 | 2095 | 0.908 | 0.1574 | No | ||
21 | TBXAS1 | 5050053 6900286 | 2228 | 0.834 | 0.1559 | No | ||
22 | GTF2B | 6860685 | 2263 | 0.810 | 0.1596 | No | ||
23 | APOBEC1 | 4610022 | 2287 | 0.801 | 0.1639 | No | ||
24 | CMAS | 2190129 | 2480 | 0.688 | 0.1582 | No | ||
25 | UBXD3 | 5050193 | 2598 | 0.634 | 0.1562 | No | ||
26 | DLX1 | 360168 | 2642 | 0.614 | 0.1581 | No | ||
27 | HEPH | 2940176 3390040 6100195 6900575 7100170 | 2723 | 0.573 | 0.1577 | No | ||
28 | RIN1 | 510593 | 2853 | 0.520 | 0.1542 | No | ||
29 | ABI3 | 1740563 | 3038 | 0.448 | 0.1473 | No | ||
30 | MCART1 | 5270059 | 3180 | 0.397 | 0.1424 | No | ||
31 | LRRFIP2 | 670575 730152 6590438 | 3289 | 0.359 | 0.1390 | No | ||
32 | VDR | 130156 510438 | 3329 | 0.348 | 0.1393 | No | ||
33 | TCF7 | 3800736 5390181 | 3339 | 0.346 | 0.1411 | No | ||
34 | PEA15 | 4590685 | 3440 | 0.313 | 0.1379 | No | ||
35 | SLC38A2 | 1470242 3800026 | 3463 | 0.306 | 0.1388 | No | ||
36 | NLK | 2030010 2450041 | 3499 | 0.295 | 0.1389 | No | ||
37 | SPRED1 | 6940706 | 3530 | 0.286 | 0.1392 | No | ||
38 | APBA2BP | 5700341 | 3619 | 0.259 | 0.1362 | No | ||
39 | BACH1 | 290195 | 3662 | 0.249 | 0.1357 | No | ||
40 | SLC22A18 | 7050168 | 3663 | 0.249 | 0.1374 | No | ||
41 | RNF34 | 3800332 4590717 5670138 | 3728 | 0.232 | 0.1355 | No | ||
42 | CDKN1A | 4050088 6400706 | 3730 | 0.231 | 0.1370 | No | ||
43 | NEK6 | 3360687 | 3818 | 0.213 | 0.1338 | No | ||
44 | COL27A1 | 1740390 | 3864 | 0.205 | 0.1327 | No | ||
45 | LAMA3 | 1190131 5290239 | 3969 | 0.184 | 0.1283 | No | ||
46 | DTNA | 1340600 1780731 2340278 2850132 | 4019 | 0.174 | 0.1269 | No | ||
47 | IDS | 360619 5720161 | 4151 | 0.153 | 0.1208 | No | ||
48 | SSH2 | 360056 | 4315 | 0.133 | 0.1129 | No | ||
49 | WASF2 | 4850592 | 4480 | 0.115 | 0.1048 | No | ||
50 | MARK1 | 450484 | 4561 | 0.108 | 0.1012 | No | ||
51 | KCNA2 | 5080403 | 4589 | 0.105 | 0.1004 | No | ||
52 | AKT3 | 1580270 3290278 | 4634 | 0.102 | 0.0987 | No | ||
53 | CMYA1 | 6900632 | 4725 | 0.095 | 0.0945 | No | ||
54 | ATP6V0D2 | 7050541 | 4799 | 0.090 | 0.0911 | No | ||
55 | PFTK1 | 1780181 | 4849 | 0.086 | 0.0891 | No | ||
56 | IL6 | 380133 | 4953 | 0.080 | 0.0840 | No | ||
57 | SLC26A1 | 2190142 | 5043 | 0.075 | 0.0797 | No | ||
58 | CALB2 | 6130170 6590368 | 5176 | 0.068 | 0.0730 | No | ||
59 | SERPINB5 | 6940050 | 5210 | 0.066 | 0.0717 | No | ||
60 | ATP6V1C2 | 6620092 | 5251 | 0.065 | 0.0700 | No | ||
61 | SNCB | 3360133 | 5427 | 0.057 | 0.0608 | No | ||
62 | IVL | 4560500 | 5429 | 0.057 | 0.0612 | No | ||
63 | PTPRN | 5900577 | 5725 | 0.048 | 0.0455 | No | ||
64 | SYNGR1 | 5130452 6650056 | 5737 | 0.047 | 0.0452 | No | ||
65 | NUDT11 | 3840239 | 5770 | 0.046 | 0.0438 | No | ||
66 | PLCD1 | 2030484 | 5822 | 0.044 | 0.0413 | No | ||
67 | MYB | 1660494 5860451 6130706 | 6007 | 0.039 | 0.0316 | No | ||
68 | ASB5 | 2760575 | 6196 | 0.034 | 0.0217 | No | ||
69 | MYOZ2 | 1050253 | 6563 | 0.026 | 0.0020 | No | ||
70 | OMG | 6760066 | 6670 | 0.023 | -0.0036 | No | ||
71 | SLC35E4 | 2370711 | 6806 | 0.020 | -0.0108 | No | ||
72 | USP13 | 1450670 | 6819 | 0.020 | -0.0113 | No | ||
73 | HS6ST2 | 520133 5550603 | 7046 | 0.016 | -0.0235 | No | ||
74 | SH3RF2 | 6200600 | 7207 | 0.013 | -0.0321 | No | ||
75 | TRPV3 | 540341 | 7659 | 0.005 | -0.0565 | No | ||
76 | IL11 | 1740398 | 7736 | 0.003 | -0.0606 | No | ||
77 | MAPRE3 | 7050504 | 7967 | -0.000 | -0.0731 | No | ||
78 | PHLDA2 | 4810494 | 8009 | -0.001 | -0.0753 | No | ||
79 | SHC3 | 2690398 | 8135 | -0.003 | -0.0821 | No | ||
80 | BNIP3 | 3140270 | 8199 | -0.004 | -0.0855 | No | ||
81 | RBP4 | 4540131 | 8423 | -0.008 | -0.0975 | No | ||
82 | SMPX | 6590440 | 8658 | -0.012 | -0.1101 | No | ||
83 | SYT2 | 60609 | 8773 | -0.014 | -0.1162 | No | ||
84 | LENEP | 4850369 | 8802 | -0.014 | -0.1176 | No | ||
85 | TNXB | 630592 3830020 5360497 7000673 | 8948 | -0.017 | -0.1254 | No | ||
86 | ANXA7 | 6110446 | 9021 | -0.018 | -0.1292 | No | ||
87 | PSMA3 | 5900047 7040161 | 9078 | -0.019 | -0.1321 | No | ||
88 | SFTPC | 3290133 | 9209 | -0.021 | -0.1390 | No | ||
89 | CPNE8 | 7040039 | 9242 | -0.022 | -0.1406 | No | ||
90 | CSF3 | 2230193 6660707 | 9275 | -0.022 | -0.1422 | No | ||
91 | PSMD11 | 2340538 6510053 | 9447 | -0.025 | -0.1513 | No | ||
92 | IGSF9 | 1770411 | 9449 | -0.025 | -0.1512 | No | ||
93 | P2RXL1 | 4730390 5220446 | 9477 | -0.026 | -0.1524 | No | ||
94 | EYA1 | 1450278 5220390 | 9835 | -0.033 | -0.1716 | No | ||
95 | GFAP | 2060092 | 9930 | -0.035 | -0.1764 | No | ||
96 | TIAL1 | 4150048 6510605 | 9953 | -0.036 | -0.1774 | No | ||
97 | TAC1 | 7000195 380706 | 9984 | -0.037 | -0.1788 | No | ||
98 | SPATS2 | 2360066 | 10071 | -0.039 | -0.1832 | No | ||
99 | FOSL1 | 430021 | 10317 | -0.043 | -0.1962 | No | ||
100 | ULK1 | 6100315 | 10347 | -0.044 | -0.1974 | No | ||
101 | DMD | 1740041 3990332 | 10389 | -0.045 | -0.1994 | No | ||
102 | CHST4 | 1190008 | 10489 | -0.047 | -0.2044 | No | ||
103 | SNCG | 3120725 | 10546 | -0.049 | -0.2071 | No | ||
104 | COL7A1 | 1230168 2190072 | 10730 | -0.053 | -0.2167 | No | ||
105 | EIF3S1 | 6130368 6770044 | 10825 | -0.055 | -0.2214 | No | ||
106 | TRIB1 | 2320435 | 10969 | -0.058 | -0.2288 | No | ||
107 | SCEL | 3190129 | 10975 | -0.058 | -0.2286 | No | ||
108 | AQP5 | 3830451 | 11019 | -0.059 | -0.2306 | No | ||
109 | DHRS3 | 360609 | 11160 | -0.063 | -0.2377 | No | ||
110 | FGF12 | 1740446 2360037 | 11185 | -0.064 | -0.2386 | No | ||
111 | ANGPT1 | 3990368 5130288 6770035 | 11193 | -0.064 | -0.2385 | No | ||
112 | ITGAX | 6130524 | 11243 | -0.065 | -0.2407 | No | ||
113 | MAPK12 | 450022 1340717 7050484 | 11301 | -0.068 | -0.2434 | No | ||
114 | OLR1 | 50025 3840484 | 11475 | -0.073 | -0.2523 | No | ||
115 | COL5A3 | 1940471 | 11490 | -0.074 | -0.2525 | No | ||
116 | FGF9 | 1050195 | 11581 | -0.077 | -0.2569 | No | ||
117 | SV2B | 3850717 | 11634 | -0.078 | -0.2592 | No | ||
118 | TLL1 | 2680315 | 11696 | -0.081 | -0.2619 | No | ||
119 | MMP7 | 1780497 | 11916 | -0.089 | -0.2732 | No | ||
120 | LRP1B | 1450193 | 12044 | -0.094 | -0.2794 | No | ||
121 | GDNF | 4050487 5720739 | 12045 | -0.094 | -0.2788 | No | ||
122 | ST18 | 5720537 | 12571 | -0.121 | -0.3064 | No | ||
123 | STX17 | 2260037 | 12604 | -0.123 | -0.3073 | No | ||
124 | PVALB | 5570450 | 12646 | -0.126 | -0.3087 | No | ||
125 | EEF1A2 | 2260162 5290086 | 12751 | -0.134 | -0.3134 | No | ||
126 | DIRAS1 | 2640270 | 12992 | -0.150 | -0.3254 | No | ||
127 | ELAVL2 | 360181 | 13114 | -0.159 | -0.3309 | No | ||
128 | PIM1 | 630047 | 13494 | -0.191 | -0.3502 | No | ||
129 | CSMD3 | 1660427 1940687 | 13606 | -0.206 | -0.3548 | No | ||
130 | NRIP3 | 1340372 | 13911 | -0.240 | -0.3696 | No | ||
131 | LY6D | 4050010 | 13994 | -0.250 | -0.3723 | No | ||
132 | IRAK1 | 4120593 | 14010 | -0.252 | -0.3714 | No | ||
133 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14274 | -0.293 | -0.3837 | No | ||
134 | RB1CC1 | 510494 7100072 | 14304 | -0.298 | -0.3832 | No | ||
135 | HCN3 | 3940438 6840750 | 14393 | -0.314 | -0.3858 | No | ||
136 | RPS20 | 1740092 | 14431 | -0.320 | -0.3857 | No | ||
137 | MRGPRF | 4780746 | 14552 | -0.341 | -0.3898 | No | ||
138 | GADD45A | 2900717 | 14582 | -0.346 | -0.3890 | No | ||
139 | PTPRR | 130121 3990273 | 14677 | -0.365 | -0.3916 | No | ||
140 | MMRN2 | 1740047 | 14773 | -0.386 | -0.3941 | No | ||
141 | TUBB4 | 5310681 | 14819 | -0.395 | -0.3939 | No | ||
142 | EPHA2 | 5890056 | 14854 | -0.403 | -0.3930 | No | ||
143 | SLC38A3 | 5340142 | 14904 | -0.415 | -0.3928 | No | ||
144 | ADRA1A | 1230446 2260390 | 15217 | -0.507 | -0.4062 | No | ||
145 | DUSP13 | 6400152 | 15219 | -0.508 | -0.4028 | No | ||
146 | DUSP14 | 1230358 | 15276 | -0.526 | -0.4022 | No | ||
147 | MDFI | 6200041 | 15343 | -0.546 | -0.4021 | No | ||
148 | CDH23 | 4250242 5290397 6550397 | 15403 | -0.570 | -0.4014 | No | ||
149 | GSTP1 | 3170102 3710707 5080368 | 15649 | -0.665 | -0.4101 | Yes | ||
150 | GABARAPL1 | 2810458 | 15682 | -0.678 | -0.4072 | Yes | ||
151 | PSMD2 | 4670706 5050364 | 15757 | -0.711 | -0.4063 | Yes | ||
152 | ARHGAP8 | 380333 5390487 | 15922 | -0.803 | -0.4097 | Yes | ||
153 | EEF1A1 | 1980193 1990195 4670735 | 15982 | -0.835 | -0.4072 | Yes | ||
154 | SLC11A1 | 940286 2810435 6370647 | 16054 | -0.870 | -0.4051 | Yes | ||
155 | DTX2 | 4210041 7000008 | 16190 | -0.950 | -0.4059 | Yes | ||
156 | BAZ2A | 730184 | 16198 | -0.958 | -0.3997 | Yes | ||
157 | PADI4 | 1740075 4810441 | 16280 | -1.002 | -0.3972 | Yes | ||
158 | PPP2R5B | 2900441 | 16536 | -1.151 | -0.4031 | Yes | ||
159 | HSPB8 | 540563 | 16555 | -1.166 | -0.3961 | Yes | ||
160 | RIT1 | 5390338 | 16617 | -1.206 | -0.3912 | Yes | ||
161 | SERTAD1 | 2680332 | 16811 | -1.348 | -0.3924 | Yes | ||
162 | VASP | 7050500 | 16831 | -1.374 | -0.3840 | Yes | ||
163 | CCL27 | 2120070 | 16905 | -1.445 | -0.3780 | Yes | ||
164 | ABHD4 | 6760450 | 16929 | -1.462 | -0.3693 | Yes | ||
165 | CLIC1 | 110600 | 16937 | -1.464 | -0.3596 | Yes | ||
166 | TGFBR2 | 1780711 1980537 6550398 | 17052 | -1.525 | -0.3553 | Yes | ||
167 | BAG2 | 2900324 | 17077 | -1.540 | -0.3461 | Yes | ||
168 | TAGLN2 | 4560121 | 17183 | -1.619 | -0.3407 | Yes | ||
169 | DCTN2 | 540471 3780717 | 17212 | -1.640 | -0.3309 | Yes | ||
170 | TNFRSF12A | 4810253 | 17287 | -1.716 | -0.3232 | Yes | ||
171 | VAT1 | 1050040 | 17308 | -1.732 | -0.3124 | Yes | ||
172 | NCDN | 50040 1980739 3520603 | 17519 | -1.916 | -0.3106 | Yes | ||
173 | ADCK4 | 1660180 | 17583 | -1.985 | -0.3004 | Yes | ||
174 | ROM1 | 3130685 | 17638 | -2.044 | -0.2893 | Yes | ||
175 | FBS1 | 2570520 | 17674 | -2.080 | -0.2770 | Yes | ||
176 | ABCF3 | 7100100 | 17676 | -2.081 | -0.2628 | Yes | ||
177 | RAB3D | 4210253 | 17701 | -2.109 | -0.2496 | Yes | ||
178 | SQSTM1 | 6550056 | 17732 | -2.162 | -0.2364 | Yes | ||
179 | HDAC3 | 4060072 | 17839 | -2.296 | -0.2264 | Yes | ||
180 | ENO1 | 5340128 | 17995 | -2.530 | -0.2174 | Yes | ||
181 | PPP1R9B | 3130619 | 18017 | -2.558 | -0.2010 | Yes | ||
182 | LMNA | 520471 1500075 3190167 4210020 | 18022 | -2.565 | -0.1837 | Yes | ||
183 | ABCA2 | 5050039 | 18231 | -2.965 | -0.1746 | Yes | ||
184 | ALS2CR2 | 6450128 7100092 | 18261 | -3.052 | -0.1552 | Yes | ||
185 | ABCD1 | 5670373 | 18368 | -3.366 | -0.1379 | Yes | ||
186 | GPSM3 | 2690154 | 18372 | -3.370 | -0.1150 | Yes | ||
187 | ABCB6 | 6350138 | 18481 | -3.862 | -0.0943 | Yes | ||
188 | POLD4 | 2320082 | 18553 | -4.501 | -0.0673 | Yes | ||
189 | GNGT2 | 540176 | 18566 | -4.702 | -0.0357 | Yes | ||
190 | ALDOA | 6290672 | 18596 | -5.593 | 0.0011 | Yes |