Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
Upregulated in class | absentNotch |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | 0.61390877 |
Normalized Enrichment Score (NES) | 1.8941522 |
Nominal p-value | 0.0 |
FDR q-value | 0.002218171 |
FWER p-Value | 0.0050 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MCL1 | 1660672 | 12 | 5.794 | 0.0296 | Yes | ||
2 | RHOT1 | 6760692 | 36 | 4.864 | 0.0537 | Yes | ||
3 | AP3S1 | 5570044 | 48 | 4.776 | 0.0780 | Yes | ||
4 | UBE2G1 | 2230546 5420528 7040463 | 80 | 4.350 | 0.0990 | Yes | ||
5 | SIN3A | 2190121 | 85 | 4.292 | 0.1212 | Yes | ||
6 | SRPK2 | 6380341 | 87 | 4.282 | 0.1435 | Yes | ||
7 | PPP3CB | 6020156 | 89 | 4.258 | 0.1657 | Yes | ||
8 | APLP2 | 3610037 | 97 | 4.170 | 0.1870 | Yes | ||
9 | BRD7 | 2120068 6200746 | 141 | 3.892 | 0.2050 | Yes | ||
10 | KBTBD2 | 2320014 | 212 | 3.580 | 0.2199 | Yes | ||
11 | NUDT4 | 6760689 | 228 | 3.497 | 0.2373 | Yes | ||
12 | FMNL2 | 4060438 | 240 | 3.452 | 0.2547 | Yes | ||
13 | ITGB1 | 5080156 6270528 | 260 | 3.381 | 0.2713 | Yes | ||
14 | CLPX | 6220156 | 280 | 3.290 | 0.2874 | Yes | ||
15 | PIAS1 | 5340301 | 284 | 3.281 | 0.3044 | Yes | ||
16 | TBK1 | 5690338 | 291 | 3.258 | 0.3211 | Yes | ||
17 | CTDSPL | 4670546 | 389 | 2.969 | 0.3313 | Yes | ||
18 | NMT1 | 5810152 | 459 | 2.796 | 0.3421 | Yes | ||
19 | DDX3X | 2190020 | 494 | 2.725 | 0.3545 | Yes | ||
20 | RYBP | 60746 | 500 | 2.714 | 0.3684 | Yes | ||
21 | MTPN | 3940167 | 515 | 2.686 | 0.3816 | Yes | ||
22 | CREBBP | 5690035 7040050 | 535 | 2.625 | 0.3943 | Yes | ||
23 | HMGCS1 | 6620452 | 551 | 2.584 | 0.4070 | Yes | ||
24 | PAIP1 | 3870576 | 563 | 2.557 | 0.4197 | Yes | ||
25 | DHX36 | 2470465 | 572 | 2.528 | 0.4325 | Yes | ||
26 | ETF1 | 6770075 | 620 | 2.447 | 0.4427 | Yes | ||
27 | NCOA1 | 3610438 | 637 | 2.418 | 0.4544 | Yes | ||
28 | EIF4ENIF1 | 2060341 | 719 | 2.292 | 0.4620 | Yes | ||
29 | SFRS3 | 770315 4230593 | 747 | 2.240 | 0.4722 | Yes | ||
30 | GNB1 | 2120397 | 750 | 2.237 | 0.4838 | Yes | ||
31 | ARID1A | 2630022 1690551 4810110 | 752 | 2.236 | 0.4954 | Yes | ||
32 | ZFX | 5900400 | 780 | 2.197 | 0.5054 | Yes | ||
33 | BTG1 | 4200735 6040131 6200133 | 783 | 2.195 | 0.5167 | Yes | ||
34 | PDPK1 | 6650168 | 815 | 2.154 | 0.5263 | Yes | ||
35 | LRP12 | 2370112 | 832 | 2.131 | 0.5365 | Yes | ||
36 | ATP2A2 | 1090075 3990279 | 939 | 1.987 | 0.5411 | Yes | ||
37 | JARID1B | 4730494 | 1026 | 1.860 | 0.5461 | Yes | ||
38 | UTX | 2900017 6770452 | 1130 | 1.741 | 0.5496 | Yes | ||
39 | FBXO33 | 1510504 | 1163 | 1.704 | 0.5568 | Yes | ||
40 | CDC73 | 1580132 | 1206 | 1.661 | 0.5632 | Yes | ||
41 | CUGBP2 | 6180121 6840139 | 1328 | 1.521 | 0.5645 | Yes | ||
42 | IRF2 | 5390044 | 1375 | 1.474 | 0.5697 | Yes | ||
43 | PHF2 | 4060300 | 1383 | 1.466 | 0.5770 | Yes | ||
44 | ANKRD50 | 870543 | 1486 | 1.358 | 0.5785 | Yes | ||
45 | ANTXR1 | 1990593 2850056 | 1489 | 1.356 | 0.5855 | Yes | ||
46 | DNAJC13 | 4730091 | 1520 | 1.317 | 0.5907 | Yes | ||
47 | PHF12 | 870400 3130687 | 1546 | 1.295 | 0.5961 | Yes | ||
48 | HEMGN | 670411 | 1617 | 1.226 | 0.5987 | Yes | ||
49 | EFTUD1 | 5360736 | 1631 | 1.215 | 0.6043 | Yes | ||
50 | ITSN2 | 780484 | 1720 | 1.139 | 0.6055 | Yes | ||
51 | VGLL4 | 6860463 | 1755 | 1.106 | 0.6094 | Yes | ||
52 | BCL7A | 4560095 | 1808 | 1.071 | 0.6122 | Yes | ||
53 | MAPK1 | 3190193 6200253 | 1876 | 1.029 | 0.6139 | Yes | ||
54 | DAB2IP | 3170064 6200441 | 2031 | 0.949 | 0.6105 | No | ||
55 | CDC14A | 4050132 | 2143 | 0.881 | 0.6091 | No | ||
56 | CLASP1 | 6860279 | 2182 | 0.859 | 0.6115 | No | ||
57 | RBM12 | 4570239 6040411 6660129 | 2303 | 0.794 | 0.6091 | No | ||
58 | HIPK1 | 110193 | 2313 | 0.786 | 0.6127 | No | ||
59 | LRIG1 | 1050136 | 2385 | 0.750 | 0.6127 | No | ||
60 | RBBP6 | 2320129 | 2647 | 0.613 | 0.6018 | No | ||
61 | MBNL2 | 3450707 | 2679 | 0.596 | 0.6032 | No | ||
62 | MLLT10 | 1410288 3290142 | 2717 | 0.577 | 0.6042 | No | ||
63 | MADD | 6100725 7000088 | 2739 | 0.566 | 0.6060 | No | ||
64 | ANKRD17 | 2120402 3850035 6400044 | 2741 | 0.565 | 0.6089 | No | ||
65 | GAB1 | 2970156 | 2785 | 0.546 | 0.6094 | No | ||
66 | TTC7B | 4760725 | 2816 | 0.533 | 0.6105 | No | ||
67 | THRAP2 | 4920600 | 2843 | 0.524 | 0.6119 | No | ||
68 | CAPN3 | 1980451 6940047 | 2950 | 0.479 | 0.6086 | No | ||
69 | ARFGEF1 | 6760494 | 3031 | 0.452 | 0.6066 | No | ||
70 | PPP1R10 | 110136 3170725 3610484 | 3083 | 0.430 | 0.6061 | No | ||
71 | PPP2R5D | 4010156 380408 5550112 5670162 | 3110 | 0.422 | 0.6069 | No | ||
72 | CITED2 | 5670114 5130088 | 3236 | 0.379 | 0.6021 | No | ||
73 | DCUN1D1 | 2360332 | 3254 | 0.375 | 0.6031 | No | ||
74 | PDE4D | 2470528 6660014 | 3326 | 0.349 | 0.6011 | No | ||
75 | TRPS1 | 870100 | 3411 | 0.324 | 0.5982 | No | ||
76 | CDH13 | 5130368 5340114 | 3602 | 0.264 | 0.5892 | No | ||
77 | GTF2IRD1 | 2030154 3990040 5080372 | 3729 | 0.232 | 0.5836 | No | ||
78 | XPO7 | 2630215 6760014 | 3739 | 0.230 | 0.5843 | No | ||
79 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 3833 | 0.211 | 0.5803 | No | ||
80 | TNFSF11 | 6350204 | 3911 | 0.196 | 0.5772 | No | ||
81 | DUSP16 | 2370082 2480450 | 4084 | 0.163 | 0.5687 | No | ||
82 | PIP5K3 | 5360112 | 4307 | 0.134 | 0.5573 | No | ||
83 | SSH2 | 360056 | 4315 | 0.133 | 0.5576 | No | ||
84 | THRAP1 | 2470121 | 4332 | 0.131 | 0.5574 | No | ||
85 | NLGN3 | 2650463 | 4393 | 0.124 | 0.5548 | No | ||
86 | CSNK1A1 | 2340427 | 4478 | 0.115 | 0.5509 | No | ||
87 | MARK1 | 450484 | 4561 | 0.108 | 0.5470 | No | ||
88 | RIMS3 | 3890563 | 4731 | 0.094 | 0.5383 | No | ||
89 | PTPN12 | 2030309 6020725 6130746 6290609 | 4851 | 0.085 | 0.5322 | No | ||
90 | TJP1 | 6350184 | 4868 | 0.084 | 0.5318 | No | ||
91 | UBE3A | 1240152 2690438 5860609 | 4870 | 0.084 | 0.5322 | No | ||
92 | GABRA5 | 5570215 | 4902 | 0.083 | 0.5309 | No | ||
93 | JUN | 840170 | 4993 | 0.077 | 0.5265 | No | ||
94 | SOX21 | 1050110 4670041 6660338 | 5023 | 0.075 | 0.5253 | No | ||
95 | SP3 | 3840338 | 5216 | 0.066 | 0.5152 | No | ||
96 | RSBN1 | 7000487 | 5617 | 0.051 | 0.4937 | No | ||
97 | ESRRG | 4010181 | 5648 | 0.050 | 0.4923 | No | ||
98 | SNX9 | 3290592 | 5671 | 0.049 | 0.4914 | No | ||
99 | MEF2C | 670025 780338 | 5821 | 0.044 | 0.4835 | No | ||
100 | BCOR | 1660452 3940053 | 5848 | 0.044 | 0.4823 | No | ||
101 | FIGN | 7000601 | 5889 | 0.042 | 0.4804 | No | ||
102 | KCNMA1 | 1450402 | 5915 | 0.042 | 0.4792 | No | ||
103 | ARHGAP5 | 2510619 3360035 | 6037 | 0.038 | 0.4729 | No | ||
104 | OVOL1 | 1690131 | 6078 | 0.037 | 0.4709 | No | ||
105 | JPH1 | 610739 | 6081 | 0.037 | 0.4710 | No | ||
106 | BHLHB5 | 6510520 | 6130 | 0.036 | 0.4686 | No | ||
107 | IRX3 | 4200112 | 6144 | 0.036 | 0.4680 | No | ||
108 | DLL1 | 1770377 | 6175 | 0.035 | 0.4666 | No | ||
109 | CCNT2 | 2100390 4150563 | 6349 | 0.030 | 0.4573 | No | ||
110 | PCDH18 | 430010 | 6562 | 0.026 | 0.4460 | No | ||
111 | RPE | 940114 | 6719 | 0.022 | 0.4376 | No | ||
112 | KCNIP4 | 4120435 7050605 | 6743 | 0.022 | 0.4364 | No | ||
113 | CUL5 | 450142 | 6866 | 0.019 | 0.4299 | No | ||
114 | GRM5 | 60528 | 6908 | 0.018 | 0.4278 | No | ||
115 | NLGN1 | 5670278 | 6987 | 0.017 | 0.4236 | No | ||
116 | PFN2 | 730040 5700026 | 7174 | 0.014 | 0.4136 | No | ||
117 | PDZRN3 | 2340131 | 7263 | 0.012 | 0.4089 | No | ||
118 | TLE4 | 1450064 1500519 | 7323 | 0.010 | 0.4057 | No | ||
119 | ADAM10 | 3780156 | 7346 | 0.010 | 0.4046 | No | ||
120 | OSBPL6 | 3800072 | 7530 | 0.007 | 0.3947 | No | ||
121 | SERTAD2 | 2810673 6840450 | 7658 | 0.005 | 0.3878 | No | ||
122 | PUM2 | 4200441 5910446 | 7693 | 0.004 | 0.3860 | No | ||
123 | ZIC2 | 1410408 | 8056 | -0.002 | 0.3663 | No | ||
124 | SP4 | 3850176 | 8094 | -0.002 | 0.3643 | No | ||
125 | NAB1 | 430739 1230114 3390736 6660056 | 8115 | -0.003 | 0.3632 | No | ||
126 | PSD2 | 2060091 | 8677 | -0.012 | 0.3328 | No | ||
127 | SPIRE2 | 450088 | 8992 | -0.017 | 0.3158 | No | ||
128 | RALGPS1 | 3440129 6400746 | 9070 | -0.019 | 0.3117 | No | ||
129 | DACH1 | 2450593 5700592 | 9161 | -0.020 | 0.3069 | No | ||
130 | CPNE8 | 7040039 | 9242 | -0.022 | 0.3027 | No | ||
131 | SRPX | 580717 1980162 | 9313 | -0.023 | 0.2990 | No | ||
132 | SLC25A26 | 4210577 | 9357 | -0.024 | 0.2968 | No | ||
133 | ZBTB11 | 6520092 | 9377 | -0.024 | 0.2959 | No | ||
134 | FOXO1A | 3120670 | 9437 | -0.025 | 0.2928 | No | ||
135 | NRXN3 | 1400546 3360471 | 9620 | -0.029 | 0.2831 | No | ||
136 | SS18 | 1940440 2900072 6900129 | 9629 | -0.029 | 0.2828 | No | ||
137 | UBE2V2 | 4210484 | 9720 | -0.031 | 0.2781 | No | ||
138 | GPC4 | 5910408 | 9741 | -0.031 | 0.2771 | No | ||
139 | EYA1 | 1450278 5220390 | 9835 | -0.033 | 0.2722 | No | ||
140 | WDFY3 | 3610041 4560333 4570273 | 9869 | -0.034 | 0.2706 | No | ||
141 | PIK3R1 | 4730671 | 9937 | -0.035 | 0.2672 | No | ||
142 | BHLHB3 | 3450438 | 10111 | -0.039 | 0.2580 | No | ||
143 | IL1A | 3610056 | 10412 | -0.045 | 0.2419 | No | ||
144 | GABRA1 | 130372 | 10443 | -0.046 | 0.2405 | No | ||
145 | AFF3 | 3870102 | 10524 | -0.048 | 0.2364 | No | ||
146 | EIF2C1 | 6900551 | 10611 | -0.050 | 0.2320 | No | ||
147 | CDH11 | 1230133 2100180 4610110 | 10844 | -0.055 | 0.2197 | No | ||
148 | LRRTM3 | 4210021 | 11035 | -0.060 | 0.2097 | No | ||
149 | TMEFF1 | 2680100 | 11095 | -0.061 | 0.2068 | No | ||
150 | DKK2 | 3610433 | 11223 | -0.065 | 0.2002 | No | ||
151 | ZIC1 | 670113 | 11283 | -0.067 | 0.1973 | No | ||
152 | POU4F1 | 2260315 | 11335 | -0.069 | 0.1949 | No | ||
153 | AK5 | 6290348 | 11599 | -0.077 | 0.1810 | No | ||
154 | BASP1 | 5700044 | 11611 | -0.077 | 0.1808 | No | ||
155 | SV2B | 3850717 | 11634 | -0.078 | 0.1801 | No | ||
156 | NXPH1 | 3870546 | 11637 | -0.078 | 0.1804 | No | ||
157 | UNC50 | 4920037 | 11838 | -0.086 | 0.1699 | No | ||
158 | PDGFC | 4200133 | 11968 | -0.091 | 0.1634 | No | ||
159 | FZD4 | 1580520 | 12005 | -0.093 | 0.1619 | No | ||
160 | TRAM2 | 3940112 | 12119 | -0.098 | 0.1563 | No | ||
161 | TTN | 2320161 4670056 6550026 | 12124 | -0.098 | 0.1566 | No | ||
162 | VPS13D | 2350451 | 12501 | -0.118 | 0.1368 | No | ||
163 | NDST1 | 1500427 5340121 | 12525 | -0.119 | 0.1361 | No | ||
164 | PCGF2 | 6370347 | 12530 | -0.119 | 0.1365 | No | ||
165 | FHOD3 | 1240541 | 12630 | -0.124 | 0.1318 | No | ||
166 | KIF1B | 1240494 2370139 4570270 6510102 | 12650 | -0.126 | 0.1314 | No | ||
167 | SEMA4C | 1980315 | 12776 | -0.135 | 0.1253 | No | ||
168 | AR | 6380167 | 12908 | -0.144 | 0.1190 | No | ||
169 | CRSP6 | 2940358 | 12979 | -0.150 | 0.1159 | No | ||
170 | SPAG8 | 4280446 | 13007 | -0.152 | 0.1153 | No | ||
171 | GAD1 | 2360035 3140167 | 13037 | -0.153 | 0.1145 | No | ||
172 | ENAH | 1690292 5700300 | 13104 | -0.158 | 0.1117 | No | ||
173 | SORCS3 | 5700309 | 13221 | -0.167 | 0.1063 | No | ||
174 | EPHA7 | 1190288 4010278 | 13222 | -0.167 | 0.1072 | No | ||
175 | COBLL1 | 4230056 6370494 | 13238 | -0.168 | 0.1072 | No | ||
176 | HS3ST3B1 | 380040 | 13244 | -0.169 | 0.1078 | No | ||
177 | WNT5A | 840685 3120152 | 13276 | -0.171 | 0.1070 | No | ||
178 | FGF13 | 630575 1570440 5360121 | 13283 | -0.172 | 0.1076 | No | ||
179 | SPRED2 | 510138 540195 | 13566 | -0.201 | 0.0933 | No | ||
180 | SNAI1 | 6590253 | 13786 | -0.228 | 0.0826 | No | ||
181 | PBX3 | 1300424 3710577 6180575 | 13878 | -0.236 | 0.0789 | No | ||
182 | PPP2R5C | 3310121 6650672 | 13892 | -0.238 | 0.0794 | No | ||
183 | RPS6KA5 | 2120563 7040546 | 13898 | -0.239 | 0.0804 | No | ||
184 | SALL1 | 5420020 7050195 | 13903 | -0.239 | 0.0814 | No | ||
185 | SPEN | 2060041 | 13919 | -0.241 | 0.0819 | No | ||
186 | HIVEP2 | 6520538 | 13945 | -0.244 | 0.0818 | No | ||
187 | SDC2 | 1980168 | 14027 | -0.255 | 0.0787 | No | ||
188 | TBC1D4 | 6420397 | 14050 | -0.258 | 0.0789 | No | ||
189 | RNF38 | 1940746 3140133 3840601 | 14144 | -0.272 | 0.0752 | No | ||
190 | AXIN1 | 3360358 6940451 | 14175 | -0.277 | 0.0751 | No | ||
191 | CDH2 | 520435 2450451 2760025 6650477 | 14221 | -0.285 | 0.0741 | No | ||
192 | UNC5A | 2120528 3060324 | 14561 | -0.342 | 0.0575 | No | ||
193 | GABRG2 | 2350402 4210204 6130279 6550037 | 14577 | -0.345 | 0.0584 | No | ||
194 | KLF3 | 5130438 | 14747 | -0.379 | 0.0512 | No | ||
195 | KPNA4 | 510369 | 14842 | -0.400 | 0.0482 | No | ||
196 | ZMYND19 | 1570706 6860551 | 14848 | -0.401 | 0.0500 | No | ||
197 | HIC2 | 4010433 | 14915 | -0.418 | 0.0486 | No | ||
198 | SIPA1L2 | 4850731 | 14971 | -0.431 | 0.0479 | No | ||
199 | SPRYD3 | 50403 | 14990 | -0.435 | 0.0492 | No | ||
200 | ATAD2 | 870242 2260687 | 15095 | -0.464 | 0.0459 | No | ||
201 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15135 | -0.474 | 0.0463 | No | ||
202 | DOCK9 | 5080037 | 15282 | -0.527 | 0.0411 | No | ||
203 | HNRPA0 | 2680048 | 15397 | -0.567 | 0.0379 | No | ||
204 | SH2D3C | 3060014 | 15479 | -0.597 | 0.0366 | No | ||
205 | USP21 | 3060446 | 15720 | -0.693 | 0.0272 | No | ||
206 | PMP22 | 4010239 6550072 | 15763 | -0.715 | 0.0286 | No | ||
207 | TMEM16D | 2650324 | 15952 | -0.819 | 0.0227 | No | ||
208 | MAST1 | 6940215 | 16059 | -0.872 | 0.0214 | No | ||
209 | ATP5A1 | 1990722 | 16158 | -0.938 | 0.0210 | No | ||
210 | BAZ2A | 730184 | 16198 | -0.958 | 0.0239 | No | ||
211 | EFNA3 | 6370390 | 16621 | -1.210 | 0.0073 | No | ||
212 | UBE2Q1 | 610348 2350114 4210717 | 16817 | -1.355 | 0.0037 | No | ||
213 | SNRP70 | 4200181 | 16874 | -1.416 | 0.0081 | No | ||
214 | E2F6 | 3120133 3850332 4070324 | 17305 | -1.729 | -0.0063 | No | ||
215 | IRF7 | 1570605 | 17336 | -1.754 | 0.0012 | No | ||
216 | VAMP2 | 2100100 | 17441 | -1.856 | 0.0053 | No | ||
217 | CHKB | 770129 | 17526 | -1.927 | 0.0108 | No | ||
218 | CRSP7 | 4230408 | 17602 | -2.007 | 0.0171 | No | ||
219 | FBS1 | 2570520 | 17674 | -2.080 | 0.0241 | No | ||
220 | OTUB1 | 610551 | 17688 | -2.097 | 0.0344 | No | ||
221 | CARM1 | 7040292 | 18268 | -3.070 | 0.0189 | No |