Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | REACTOME_G2_M_CHECKPOINTS |
| Enrichment Score (ES) | 0.67889786 |
| Normalized Enrichment Score (NES) | 1.5839391 |
| Nominal p-value | 0.013544018 |
| FDR q-value | 0.27728173 |
| FWER p-Value | 0.947 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MCM4 | 2760673 5420711 | 225 | 3.505 | 0.0983 | Yes | ||
| 2 | RFC4 | 3800082 6840142 | 318 | 3.159 | 0.1928 | Yes | ||
| 3 | RPA1 | 360452 | 466 | 2.775 | 0.2722 | Yes | ||
| 4 | ORC5L | 1940133 1940711 | 754 | 2.234 | 0.3271 | Yes | ||
| 5 | RPA3 | 5700136 | 822 | 2.144 | 0.3910 | Yes | ||
| 6 | CCNB1 | 4590433 4780372 | 841 | 2.121 | 0.4568 | Yes | ||
| 7 | RFC3 | 1980600 | 992 | 1.896 | 0.5084 | Yes | ||
| 8 | CDC25A | 3800184 | 1196 | 1.670 | 0.5501 | Yes | ||
| 9 | MCM6 | 60092 540181 6510110 | 1526 | 1.312 | 0.5737 | Yes | ||
| 10 | HUS1 | 3440494 3800156 | 1757 | 1.106 | 0.5961 | Yes | ||
| 11 | CDK2 | 130484 2260301 4010088 5050110 | 1778 | 1.088 | 0.6293 | Yes | ||
| 12 | CDC7 | 4060546 4850041 | 1905 | 1.007 | 0.6542 | Yes | ||
| 13 | RFC5 | 3800452 6020091 | 2218 | 0.838 | 0.6638 | Yes | ||
| 14 | MCM3 | 5570068 | 2610 | 0.627 | 0.6625 | Yes | ||
| 15 | MCM7 | 3290292 5220056 | 2662 | 0.607 | 0.6789 | Yes | ||
| 16 | WEE1 | 3390070 | 3430 | 0.317 | 0.6476 | No | ||
| 17 | CDC45L | 70537 3130114 | 3466 | 0.305 | 0.6554 | No | ||
| 18 | ORC2L | 1990470 6510019 | 3731 | 0.231 | 0.6484 | No | ||
| 19 | RAD9B | 2320064 | 3782 | 0.220 | 0.6527 | No | ||
| 20 | CHEK1 | 50167 1940300 | 3941 | 0.188 | 0.6501 | No | ||
| 21 | ORC4L | 4230538 5550288 | 3986 | 0.180 | 0.6534 | No | ||
| 22 | CDC25C | 2570673 4760161 6520707 | 6003 | 0.040 | 0.5462 | No | ||
| 23 | CCNB2 | 6510528 | 6991 | 0.017 | 0.4936 | No | ||
| 24 | MCM10 | 4920632 | 9286 | -0.023 | 0.3709 | No | ||
| 25 | ATM | 3610110 4050524 | 10515 | -0.048 | 0.3063 | No | ||
| 26 | RAD1 | 4200551 | 10569 | -0.049 | 0.3050 | No | ||
| 27 | MCM2 | 5050139 | 11994 | -0.092 | 0.2313 | No | ||
| 28 | MCM5 | 2680647 | 15984 | -0.836 | 0.0430 | No | ||
| 29 | ORC1L | 2370328 6110390 | 16632 | -1.219 | 0.0466 | No | ||
| 30 | RPA2 | 2760301 5420195 | 17509 | -1.909 | 0.0596 | No |
