Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | CYTOKINE_PRODUCTION |
| Enrichment Score (ES) | -0.6430038 |
| Normalized Enrichment Score (NES) | -1.5582488 |
| Nominal p-value | 0.003984064 |
| FDR q-value | 0.24524792 |
| FWER p-Value | 0.982 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SOD1 | 5890070 | 670 | 2.873 | 0.0116 | No | ||
| 2 | INHBB | 2680092 | 1032 | 2.255 | 0.0296 | No | ||
| 3 | APOA1 | 110152 | 1105 | 2.178 | 0.0618 | No | ||
| 4 | CADM1 | 6620128 | 1442 | 1.746 | 0.0727 | No | ||
| 5 | MAP3K7 | 6040068 | 2647 | 0.813 | 0.0213 | No | ||
| 6 | TLR4 | 1690167 2650369 3850333 | 3696 | 0.352 | -0.0293 | No | ||
| 7 | SFTPD | 6510181 | 3851 | 0.310 | -0.0325 | No | ||
| 8 | IL12A | 7100551 | 3870 | 0.305 | -0.0284 | No | ||
| 9 | IL18 | 6180039 | 4139 | 0.248 | -0.0387 | No | ||
| 10 | ATP6AP2 | 4010059 5080315 7100347 6660484 | 4227 | 0.232 | -0.0395 | No | ||
| 11 | CD24 | 1780091 | 4251 | 0.230 | -0.0369 | No | ||
| 12 | TLR6 | 510102 3390148 | 5055 | 0.132 | -0.0780 | No | ||
| 13 | APOA2 | 6510364 6860411 | 5175 | 0.121 | -0.0824 | No | ||
| 14 | BCL3 | 3990440 | 5360 | 0.110 | -0.0905 | No | ||
| 15 | CHRNA7 | 2970446 | 5367 | 0.109 | -0.0890 | No | ||
| 16 | ELA2 | 1570452 5270129 | 5397 | 0.107 | -0.0888 | No | ||
| 17 | NLRC4 | 5570332 | 5744 | 0.089 | -0.1060 | No | ||
| 18 | GLMN | 5290563 5890239 | 5979 | 0.079 | -0.1173 | No | ||
| 19 | IL4 | 6020537 | 6040 | 0.077 | -0.1192 | No | ||
| 20 | INHA | 6100102 | 6183 | 0.072 | -0.1257 | No | ||
| 21 | TLR7 | 3140300 | 6265 | 0.069 | -0.1289 | No | ||
| 22 | CALCA | 5860167 | 6650 | 0.057 | -0.1486 | No | ||
| 23 | IL12B | 460008 | 7246 | 0.043 | -0.1800 | No | ||
| 24 | IL9 | 3440338 | 7566 | 0.037 | -0.1966 | No | ||
| 25 | TNFRSF8 | 870136 4810446 | 7735 | 0.033 | -0.2051 | No | ||
| 26 | TLR9 | 670093 670706 | 8436 | 0.021 | -0.2425 | No | ||
| 27 | NLRP2 | 580750 | 8789 | 0.015 | -0.2612 | No | ||
| 28 | CIDEA | 4560020 | 8998 | 0.012 | -0.2722 | No | ||
| 29 | TLR8 | 1240092 | 9156 | 0.010 | -0.2805 | No | ||
| 30 | TLR3 | 6760451 | 9563 | 0.004 | -0.3023 | No | ||
| 31 | IL6 | 380133 | 9755 | 0.001 | -0.3126 | No | ||
| 32 | ABCA1 | 6290156 | 9882 | -0.001 | -0.3194 | No | ||
| 33 | IL27 | 1990324 | 9887 | -0.001 | -0.3196 | No | ||
| 34 | GHSR | 1980465 7050521 | 10219 | -0.007 | -0.3373 | No | ||
| 35 | CD40LG | 3120270 | 10691 | -0.014 | -0.3624 | No | ||
| 36 | IFNG | 5670592 | 11703 | -0.032 | -0.4164 | No | ||
| 37 | TGFB2 | 4920292 | 11759 | -0.033 | -0.4188 | No | ||
| 38 | MALT1 | 4670292 | 11838 | -0.034 | -0.4225 | No | ||
| 39 | TLR1 | 1410524 | 12176 | -0.042 | -0.4399 | No | ||
| 40 | HIF1A | 5670605 | 12295 | -0.045 | -0.4455 | No | ||
| 41 | EREG | 50519 4920129 | 13211 | -0.074 | -0.4936 | No | ||
| 42 | IL17F | 670577 | 13866 | -0.110 | -0.5270 | No | ||
| 43 | GHRL | 2360619 6760438 | 13928 | -0.115 | -0.5284 | No | ||
| 44 | NLRP3 | 1980064 4010180 | 14157 | -0.134 | -0.5385 | No | ||
| 45 | EBI3 | 5340300 | 14685 | -0.195 | -0.5636 | No | ||
| 46 | CRTAM | 4480110 | 14734 | -0.203 | -0.5628 | No | ||
| 47 | NOD2 | 2510050 | 14972 | -0.257 | -0.5713 | No | ||
| 48 | PRG3 | 6220020 | 15398 | -0.390 | -0.5878 | No | ||
| 49 | TRAF6 | 4810292 6200132 | 16386 | -0.933 | -0.6255 | Yes | ||
| 50 | FOXP3 | 940707 1850692 | 16608 | -1.071 | -0.6196 | Yes | ||
| 51 | IRF4 | 610133 | 17043 | -1.501 | -0.6181 | Yes | ||
| 52 | PYCARD | 2100750 | 17291 | -1.813 | -0.6013 | Yes | ||
| 53 | MAST2 | 6200348 | 17727 | -2.546 | -0.5825 | Yes | ||
| 54 | CD28 | 1400739 4210093 | 17736 | -2.566 | -0.5403 | Yes | ||
| 55 | SMAD4 | 5670519 | 17833 | -2.774 | -0.4994 | Yes | ||
| 56 | BCL10 | 2360397 | 18080 | -3.458 | -0.4553 | Yes | ||
| 57 | SMAD3 | 6450671 | 18213 | -3.958 | -0.3967 | Yes | ||
| 58 | SPN | 3520338 3870671 | 18293 | -4.381 | -0.3282 | Yes | ||
| 59 | NOD1 | 2360368 | 18350 | -4.710 | -0.2530 | Yes | ||
| 60 | CARD11 | 70338 | 18363 | -4.788 | -0.1742 | Yes | ||
| 61 | TRAF2 | 5900148 | 18419 | -5.207 | -0.0907 | Yes | ||
| 62 | LTB | 3990672 | 18503 | -6.099 | 0.0061 | Yes |
