Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$USF_02 |
Enrichment Score (ES) | 0.4484873 |
Normalized Enrichment Score (NES) | 1.254616 |
Nominal p-value | 0.043763675 |
FDR q-value | 0.8707864 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PFDN2 | 4230156 | 44 | 6.560 | 0.0330 | Yes | ||
2 | SNX8 | 3450315 | 65 | 5.832 | 0.0633 | Yes | ||
3 | BAX | 3830008 | 75 | 5.639 | 0.0932 | Yes | ||
4 | GRN | 4050239 | 113 | 5.179 | 0.1192 | Yes | ||
5 | EIF4B | 5390563 5270577 | 144 | 4.909 | 0.1440 | Yes | ||
6 | AATF | 5220575 | 212 | 4.422 | 0.1642 | Yes | ||
7 | NUDC | 4780025 | 234 | 4.307 | 0.1863 | Yes | ||
8 | UTP14A | 6590048 | 300 | 3.970 | 0.2041 | Yes | ||
9 | ASNA1 | 3830041 | 315 | 3.931 | 0.2246 | Yes | ||
10 | DDX3X | 2190020 | 355 | 3.736 | 0.2426 | Yes | ||
11 | VPS16 | 430064 3390041 6860301 | 448 | 3.424 | 0.2561 | Yes | ||
12 | AKAP12 | 1450739 | 474 | 3.321 | 0.2726 | Yes | ||
13 | RFC1 | 1190673 | 497 | 3.258 | 0.2890 | Yes | ||
14 | PABPC1 | 2650180 2690253 6020632 1990270 | 553 | 3.139 | 0.3029 | Yes | ||
15 | CLN3 | 780368 | 562 | 3.127 | 0.3194 | Yes | ||
16 | HNRPA1 | 4670398 5050687 | 565 | 3.124 | 0.3361 | Yes | ||
17 | MRPL27 | 2060131 | 766 | 2.689 | 0.3397 | Yes | ||
18 | CCAR1 | 3190092 | 832 | 2.558 | 0.3500 | Yes | ||
19 | TIMM8A | 110279 | 837 | 2.548 | 0.3635 | Yes | ||
20 | UBE4B | 780008 3610154 | 870 | 2.501 | 0.3753 | Yes | ||
21 | SUPV3L1 | 1170072 | 910 | 2.440 | 0.3863 | Yes | ||
22 | PER1 | 3290315 | 1057 | 2.234 | 0.3904 | Yes | ||
23 | COMMD3 | 2510259 | 1097 | 2.185 | 0.4001 | Yes | ||
24 | UMPS | 2340541 4730438 | 1214 | 2.044 | 0.4048 | Yes | ||
25 | OPRS1 | 6130128 6290717 | 1219 | 2.040 | 0.4156 | Yes | ||
26 | PTGES2 | 4210097 | 1393 | 1.817 | 0.4160 | Yes | ||
27 | GPR65 | 3120551 | 1493 | 1.688 | 0.4197 | Yes | ||
28 | ATP6V1C1 | 2690324 5220528 | 1548 | 1.632 | 0.4256 | Yes | ||
29 | CDKN2C | 5050750 5130148 | 1569 | 1.604 | 0.4332 | Yes | ||
30 | CD164 | 3830594 | 1626 | 1.561 | 0.4385 | Yes | ||
31 | RHEBL1 | 2810576 | 1695 | 1.504 | 0.4430 | Yes | ||
32 | PRPS1 | 6350129 | 1749 | 1.447 | 0.4479 | Yes | ||
33 | ARPP-19 | 5700025 | 1872 | 1.339 | 0.4485 | Yes | ||
34 | TOPORS | 4060592 | 2078 | 1.160 | 0.4436 | No | ||
35 | ATF4 | 730441 1740195 | 2208 | 1.046 | 0.4423 | No | ||
36 | TAF6L | 1850056 | 2394 | 0.972 | 0.4375 | No | ||
37 | UBXD3 | 5050193 | 2554 | 0.873 | 0.4336 | No | ||
38 | MCAM | 5130270 6620577 | 2633 | 0.823 | 0.4338 | No | ||
39 | H2AFY | 4730750 | 2766 | 0.736 | 0.4306 | No | ||
40 | STC2 | 4920601 | 2854 | 0.691 | 0.4296 | No | ||
41 | RPS2 | 1340647 | 3005 | 0.619 | 0.4248 | No | ||
42 | ATP6V1A | 6590242 | 3053 | 0.596 | 0.4254 | No | ||
43 | RAI14 | 770288 1660075 | 3112 | 0.565 | 0.4253 | No | ||
44 | COPZ1 | 6940100 | 3174 | 0.536 | 0.4249 | No | ||
45 | RAB3IL1 | 380685 5420176 | 3220 | 0.517 | 0.4253 | No | ||
46 | GPX1 | 4150093 | 3255 | 0.503 | 0.4261 | No | ||
47 | NCOA6 | 1780333 6450110 | 3317 | 0.480 | 0.4254 | No | ||
48 | PTMA | 5570148 | 3374 | 0.457 | 0.4248 | No | ||
49 | TCERG1 | 2350551 4540397 5220746 | 3721 | 0.345 | 0.4079 | No | ||
50 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 3813 | 0.319 | 0.4047 | No | ||
51 | GTF2H1 | 2570746 2650148 | 3831 | 0.315 | 0.4055 | No | ||
52 | LAMC2 | 450692 2680041 4200059 4670148 | 3956 | 0.286 | 0.4003 | No | ||
53 | ALDH6A1 | 1770746 | 4033 | 0.270 | 0.3976 | No | ||
54 | SIRT1 | 1190731 | 4232 | 0.232 | 0.3882 | No | ||
55 | DHX35 | 1230440 | 4339 | 0.215 | 0.3836 | No | ||
56 | SYNPO2L | 5390719 | 4422 | 0.202 | 0.3802 | No | ||
57 | C4A | 360286 3830100 5220750 6420132 | 4425 | 0.202 | 0.3812 | No | ||
58 | SSR1 | 5890100 | 4510 | 0.190 | 0.3777 | No | ||
59 | RAB9A | 1690279 3710671 | 4514 | 0.189 | 0.3785 | No | ||
60 | BLNK | 70288 6590092 | 4809 | 0.153 | 0.3634 | No | ||
61 | ETV1 | 70735 2940603 5080463 | 4979 | 0.138 | 0.3550 | No | ||
62 | PPARGC1A | 4670040 | 5446 | 0.104 | 0.3303 | No | ||
63 | PICALM | 1940280 | 5577 | 0.097 | 0.3237 | No | ||
64 | TCF12 | 3610324 7000156 | 5640 | 0.094 | 0.3209 | No | ||
65 | SMCR8 | 730653 | 5851 | 0.084 | 0.3099 | No | ||
66 | POGK | 5290315 | 6276 | 0.069 | 0.2873 | No | ||
67 | ZIC3 | 380020 | 6894 | 0.051 | 0.2541 | No | ||
68 | EIF3S10 | 1190079 3840176 | 6952 | 0.049 | 0.2513 | No | ||
69 | PLS3 | 3290082 | 7053 | 0.046 | 0.2461 | No | ||
70 | LIN28 | 6590672 | 7153 | 0.044 | 0.2410 | No | ||
71 | DNMT3A | 4050068 4810717 | 7333 | 0.041 | 0.2315 | No | ||
72 | PIK3R1 | 4730671 | 7432 | 0.039 | 0.2264 | No | ||
73 | HNRPD | 4120021 | 7929 | 0.029 | 0.1997 | No | ||
74 | XPO1 | 540707 | 7976 | 0.029 | 0.1973 | No | ||
75 | TYR | 5690139 | 7990 | 0.028 | 0.1968 | No | ||
76 | SEMA3A | 1780064 | 8100 | 0.026 | 0.1910 | No | ||
77 | HNRPH2 | 2630040 5720671 | 8119 | 0.026 | 0.1902 | No | ||
78 | FOXD3 | 6550156 | 8196 | 0.025 | 0.1862 | No | ||
79 | APLN | 6620632 | 8202 | 0.025 | 0.1860 | No | ||
80 | VLDLR | 870722 3060047 5340452 6550131 | 8322 | 0.023 | 0.1797 | No | ||
81 | NPTX1 | 3710736 | 8391 | 0.022 | 0.1761 | No | ||
82 | HOXC5 | 1580017 | 8460 | 0.021 | 0.1726 | No | ||
83 | FZD6 | 360288 | 8476 | 0.021 | 0.1719 | No | ||
84 | SOX10 | 6200538 | 8490 | 0.020 | 0.1713 | No | ||
85 | IRS4 | 430341 1190450 | 8523 | 0.020 | 0.1696 | No | ||
86 | SLC17A2 | 870593 2810035 | 8564 | 0.019 | 0.1676 | No | ||
87 | CRLF1 | 3520092 | 8648 | 0.018 | 0.1632 | No | ||
88 | SLC1A7 | 1990181 | 8709 | 0.017 | 0.1600 | No | ||
89 | HOXD10 | 6100039 | 8735 | 0.016 | 0.1587 | No | ||
90 | GLA | 4610364 | 8753 | 0.016 | 0.1579 | No | ||
91 | ARMET | 5130670 | 9005 | 0.012 | 0.1443 | No | ||
92 | UBXD2 | 4280092 | 9008 | 0.012 | 0.1443 | No | ||
93 | GZMK | 1410148 | 9035 | 0.011 | 0.1429 | No | ||
94 | AP1S2 | 780279 4280707 | 9238 | 0.008 | 0.1320 | No | ||
95 | NPM1 | 4730427 | 9337 | 0.007 | 0.1268 | No | ||
96 | MTHFD1 | 5900398 6520427 | 9650 | 0.003 | 0.1099 | No | ||
97 | CPT1A | 6350093 | 9668 | 0.002 | 0.1089 | No | ||
98 | VNN1 | 3940400 | 9823 | -0.000 | 0.1006 | No | ||
99 | HOXA11 | 6980133 | 9947 | -0.002 | 0.0939 | No | ||
100 | FMR1 | 5050075 | 9997 | -0.003 | 0.0913 | No | ||
101 | BMP6 | 2100128 | 10137 | -0.005 | 0.0838 | No | ||
102 | CLCN5 | 4200390 | 10278 | -0.007 | 0.0762 | No | ||
103 | OMG | 6760066 | 10593 | -0.012 | 0.0593 | No | ||
104 | TNRC15 | 6760746 | 10771 | -0.015 | 0.0497 | No | ||
105 | RHOQ | 520161 | 11003 | -0.019 | 0.0373 | No | ||
106 | NEUROD1 | 3060619 | 11111 | -0.021 | 0.0316 | No | ||
107 | TOM1L2 | 4810465 | 11232 | -0.023 | 0.0252 | No | ||
108 | LHFP | 3440368 | 11268 | -0.024 | 0.0235 | No | ||
109 | TESK2 | 6520524 | 11382 | -0.026 | 0.0175 | No | ||
110 | FGF14 | 2630390 3520075 6770048 | 11483 | -0.027 | 0.0122 | No | ||
111 | TGFB2 | 4920292 | 11759 | -0.033 | -0.0025 | No | ||
112 | BDNF | 2940128 3520368 | 11802 | -0.034 | -0.0046 | No | ||
113 | CARKL | 6020068 | 11960 | -0.037 | -0.0129 | No | ||
114 | RNF128 | 1230300 5670273 | 12190 | -0.043 | -0.0251 | No | ||
115 | PFKFB1 | 2370128 | 12210 | -0.043 | -0.0259 | No | ||
116 | CAPN6 | 1740168 | 12469 | -0.049 | -0.0397 | No | ||
117 | SUMF1 | 730050 | 12590 | -0.053 | -0.0459 | No | ||
118 | HOXB5 | 2900538 | 12623 | -0.054 | -0.0473 | No | ||
119 | CREB5 | 2320368 | 12691 | -0.056 | -0.0507 | No | ||
120 | GGN | 1410528 4210082 5290170 | 12732 | -0.057 | -0.0525 | No | ||
121 | SEC23IP | 4540484 6200047 | 12931 | -0.063 | -0.0629 | No | ||
122 | KCNE4 | 2470102 | 12963 | -0.065 | -0.0643 | No | ||
123 | MAX | 5220021 | 13015 | -0.066 | -0.0667 | No | ||
124 | CALR | 510446 | 13085 | -0.069 | -0.0700 | No | ||
125 | SLC31A2 | 1450577 | 13235 | -0.075 | -0.0777 | No | ||
126 | CBX5 | 3830072 6290167 | 13495 | -0.086 | -0.0913 | No | ||
127 | DUSP8 | 6650039 | 13541 | -0.090 | -0.0933 | No | ||
128 | TAC1 | 7000195 380706 | 13761 | -0.102 | -0.1046 | No | ||
129 | ELAVL3 | 2850014 | 13765 | -0.102 | -0.1042 | No | ||
130 | UBE2B | 4780497 | 13803 | -0.105 | -0.1056 | No | ||
131 | LRP5 | 2100397 3170484 | 13839 | -0.108 | -0.1069 | No | ||
132 | NRIP3 | 1340372 | 14161 | -0.134 | -0.1236 | No | ||
133 | GTF2A1 | 4120138 4920524 5390110 1230397 | 14323 | -0.149 | -0.1316 | No | ||
134 | DUSP7 | 2940309 | 14406 | -0.157 | -0.1352 | No | ||
135 | NFX1 | 450504 | 14620 | -0.186 | -0.1457 | No | ||
136 | RPS28 | 3830221 | 14941 | -0.248 | -0.1617 | No | ||
137 | ILF3 | 940722 3190647 6520110 | 15016 | -0.268 | -0.1643 | No | ||
138 | CYR61 | 1240408 5290026 4120452 6550008 | 15080 | -0.286 | -0.1662 | No | ||
139 | BTBD14B | 3520601 4280162 | 15153 | -0.306 | -0.1684 | No | ||
140 | HOXB7 | 4540706 4610358 | 15205 | -0.323 | -0.1695 | No | ||
141 | DVL2 | 6110162 | 15325 | -0.365 | -0.1739 | No | ||
142 | EIF4E | 1580403 70133 6380215 | 15331 | -0.366 | -0.1722 | No | ||
143 | NDUFA7 | 5900722 | 15414 | -0.396 | -0.1746 | No | ||
144 | STK16 | 1740154 | 15428 | -0.402 | -0.1731 | No | ||
145 | EGLN2 | 540086 | 15438 | -0.407 | -0.1714 | No | ||
146 | MTCH2 | 3780603 6620215 | 15458 | -0.418 | -0.1702 | No | ||
147 | SLC39A5 | 2900100 4610440 | 15476 | -0.423 | -0.1688 | No | ||
148 | LAMA3 | 1190131 5290239 | 15511 | -0.437 | -0.1683 | No | ||
149 | DCTN4 | 3390010 5550170 | 15512 | -0.437 | -0.1659 | No | ||
150 | GNB2 | 2350053 | 15595 | -0.470 | -0.1679 | No | ||
151 | TOP3A | 7000435 | 15691 | -0.517 | -0.1702 | No | ||
152 | HIVEP1 | 3850632 | 15928 | -0.631 | -0.1796 | No | ||
153 | SLC12A6 | 610278 1980035 5340671 | 15937 | -0.634 | -0.1766 | No | ||
154 | COQ4 | 1660551 | 16009 | -0.678 | -0.1768 | No | ||
155 | MAT2A | 4070026 4730079 6020280 | 16205 | -0.802 | -0.1831 | No | ||
156 | SESN3 | 110687 | 16345 | -0.907 | -0.1857 | No | ||
157 | UROD | 2470494 | 16563 | -1.036 | -0.1919 | No | ||
158 | EPC1 | 1570050 5290095 6900193 | 16571 | -1.040 | -0.1867 | No | ||
159 | FEN1 | 1770541 | 16647 | -1.102 | -0.1848 | No | ||
160 | CHD4 | 5420059 6130338 6380717 | 16744 | -1.194 | -0.1836 | No | ||
161 | MAP4K1 | 4060692 | 16760 | -1.214 | -0.1779 | No | ||
162 | UBE2L6 | 60048 1170687 | 16772 | -1.228 | -0.1718 | No | ||
163 | COMMD8 | 5890358 | 16835 | -1.285 | -0.1683 | No | ||
164 | DUSP1 | 6860121 | 16878 | -1.331 | -0.1634 | No | ||
165 | ATF7IP | 2690176 6770021 | 16981 | -1.427 | -0.1612 | No | ||
166 | PPM1A | 1170301 5900273 | 17014 | -1.465 | -0.1551 | No | ||
167 | SLC23A2 | 6660722 | 17195 | -1.700 | -0.1556 | No | ||
168 | RUNX1 | 3840711 | 17468 | -2.087 | -0.1591 | No | ||
169 | DDIT3 | 780373 | 17608 | -2.325 | -0.1542 | No | ||
170 | SQSTM1 | 6550056 | 17609 | -2.328 | -0.1416 | No | ||
171 | CTNS | 4480048 | 17796 | -2.683 | -0.1372 | No | ||
172 | BRDT | 3940102 | 17940 | -2.994 | -0.1288 | No | ||
173 | DNAJB5 | 2900215 | 17957 | -3.044 | -0.1133 | No | ||
174 | KBTBD2 | 2320014 | 17988 | -3.150 | -0.0979 | No | ||
175 | GABARAP | 1450286 | 18089 | -3.487 | -0.0846 | No | ||
176 | NIT1 | 1230338 3940671 | 18256 | -4.174 | -0.0711 | No | ||
177 | PIP5K1A | 4560672 | 18356 | -4.744 | -0.0509 | No | ||
178 | ZFYVE26 | 6860152 | 18368 | -4.851 | -0.0253 | No | ||
179 | ISGF3G | 3190131 7100142 | 18568 | -7.181 | 0.0026 | No |