Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$NFKB_Q6_01 |
Enrichment Score (ES) | -0.5793454 |
Normalized Enrichment Score (NES) | -1.5584965 |
Nominal p-value | 0.0 |
FDR q-value | 0.18393698 |
FWER p-Value | 0.519 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PCBP4 | 6350722 | 270 | 4.138 | 0.0096 | No | ||
2 | COL27A1 | 1740390 | 442 | 3.448 | 0.0205 | No | ||
3 | TCEA2 | 6370546 | 518 | 3.213 | 0.0352 | No | ||
4 | NFKBIB | 2260167 | 687 | 2.854 | 0.0428 | No | ||
5 | BMF | 610102 | 745 | 2.730 | 0.0557 | No | ||
6 | ARHGAP8 | 380333 5390487 | 853 | 2.517 | 0.0646 | No | ||
7 | UBE2H | 1980142 2970079 | 1087 | 2.198 | 0.0649 | No | ||
8 | VCAM1 | 2900450 | 1226 | 2.029 | 0.0693 | No | ||
9 | PRKCD | 770592 | 1385 | 1.829 | 0.0714 | No | ||
10 | AMOTL1 | 380279 | 1502 | 1.678 | 0.0749 | No | ||
11 | ENO3 | 5270136 | 1602 | 1.577 | 0.0788 | No | ||
12 | SEC61A1 | 3390437 | 1873 | 1.336 | 0.0720 | No | ||
13 | TP53 | 6130707 | 1986 | 1.229 | 0.0731 | No | ||
14 | CYLD | 6590079 | 2137 | 1.107 | 0.0715 | No | ||
15 | UPF2 | 4810471 | 2162 | 1.087 | 0.0765 | No | ||
16 | NDRG2 | 450403 | 2230 | 1.033 | 0.0789 | No | ||
17 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 2403 | 0.969 | 0.0753 | No | ||
18 | NR3C1 | 630563 | 2648 | 0.813 | 0.0668 | No | ||
19 | RBMS1 | 6400014 | 2796 | 0.721 | 0.0631 | No | ||
20 | RASGRP4 | 540102 | 3039 | 0.603 | 0.0535 | No | ||
21 | UBE2D3 | 3190452 | 3104 | 0.570 | 0.0534 | No | ||
22 | IL27RA | 940093 | 3218 | 0.518 | 0.0503 | No | ||
23 | RAP2C | 1690132 | 3675 | 0.360 | 0.0277 | No | ||
24 | IL12A | 7100551 | 3870 | 0.305 | 0.0189 | No | ||
25 | ASH1L | 2510402 5360687 6650685 | 4018 | 0.274 | 0.0126 | No | ||
26 | REV3L | 1090717 | 4020 | 0.273 | 0.0141 | No | ||
27 | CD69 | 380167 4730088 | 4039 | 0.269 | 0.0147 | No | ||
28 | GPHN | 3290195 3840121 | 4117 | 0.252 | 0.0120 | No | ||
29 | TNFSF18 | 1990458 2850520 | 4193 | 0.237 | 0.0093 | No | ||
30 | EGF | 5220154 | 4215 | 0.234 | 0.0096 | No | ||
31 | CLCN1 | 840161 | 4346 | 0.214 | 0.0038 | No | ||
32 | NR2F2 | 3170609 3310577 | 4356 | 0.213 | 0.0045 | No | ||
33 | CSF3 | 2230193 6660707 | 4531 | 0.187 | -0.0038 | No | ||
34 | NFAT5 | 2510411 5890195 6550152 | 4702 | 0.165 | -0.0120 | No | ||
35 | SNAP25 | 360520 | 4856 | 0.149 | -0.0195 | No | ||
36 | FTHL17 | 6550193 | 4900 | 0.144 | -0.0210 | No | ||
37 | BAI2 | 380632 630113 6650170 | 4945 | 0.141 | -0.0225 | No | ||
38 | TRIM47 | 5080717 | 4971 | 0.138 | -0.0231 | No | ||
39 | ETV1 | 70735 2940603 5080463 | 4979 | 0.138 | -0.0226 | No | ||
40 | SLC6A12 | 3170685 | 5152 | 0.123 | -0.0312 | No | ||
41 | GRK5 | 1940348 4670053 | 5226 | 0.118 | -0.0345 | No | ||
42 | IL13 | 7040021 | 5348 | 0.110 | -0.0404 | No | ||
43 | BCL3 | 3990440 | 5360 | 0.110 | -0.0404 | No | ||
44 | IFNB1 | 1400142 | 5467 | 0.103 | -0.0455 | No | ||
45 | NTN1 | 5700600 | 5528 | 0.100 | -0.0482 | No | ||
46 | HSD3B7 | 1410129 | 5529 | 0.100 | -0.0476 | No | ||
47 | DAP3 | 1660528 2120039 5420593 | 5537 | 0.099 | -0.0474 | No | ||
48 | TNFRSF1B | 3990035 5860372 | 5701 | 0.091 | -0.0557 | No | ||
49 | RALGDS | 430463 | 5823 | 0.085 | -0.0617 | No | ||
50 | SIRT2 | 630494 | 6263 | 0.069 | -0.0851 | No | ||
51 | PTGES | 1690075 | 6418 | 0.064 | -0.0931 | No | ||
52 | SMPD3 | 520164 | 6443 | 0.064 | -0.0940 | No | ||
53 | SHOX2 | 3190438 6450059 | 6517 | 0.061 | -0.0976 | No | ||
54 | CNTNAP1 | 6650132 | 6757 | 0.054 | -0.1103 | No | ||
55 | POU2F3 | 2030601 | 7060 | 0.046 | -0.1264 | No | ||
56 | RIN2 | 2450184 | 7078 | 0.046 | -0.1270 | No | ||
57 | EDN2 | 6760647 | 7401 | 0.040 | -0.1442 | No | ||
58 | BCL6B | 60047 | 7499 | 0.038 | -0.1493 | No | ||
59 | PTPRJ | 4010707 | 7521 | 0.037 | -0.1502 | No | ||
60 | HSD11B2 | 5900053 | 7736 | 0.033 | -0.1616 | No | ||
61 | PHOX2B | 5270075 | 7886 | 0.030 | -0.1695 | No | ||
62 | KRTAP13-1 | 2600242 | 8477 | 0.021 | -0.2013 | No | ||
63 | CREB1 | 1500717 2230358 3610600 6550601 | 8536 | 0.020 | -0.2044 | No | ||
64 | BMP2K | 60541 5570504 | 8689 | 0.017 | -0.2125 | No | ||
65 | FGF17 | 3130022 | 8847 | 0.014 | -0.2209 | No | ||
66 | MSX1 | 2650309 | 8971 | 0.012 | -0.2275 | No | ||
67 | IL7 | 5360440 | 9052 | 0.011 | -0.2318 | No | ||
68 | TNFSF15 | 360341 | 9124 | 0.010 | -0.2356 | No | ||
69 | MADCAM1 | 1580010 | 9162 | 0.009 | -0.2375 | No | ||
70 | AP1S2 | 780279 4280707 | 9238 | 0.008 | -0.2415 | No | ||
71 | HTR3B | 430438 520301 | 9297 | 0.008 | -0.2446 | No | ||
72 | ZBTB11 | 6520092 | 9578 | 0.004 | -0.2598 | No | ||
73 | IER5 | 2350575 | 9837 | -0.001 | -0.2738 | No | ||
74 | IL27 | 1990324 | 9887 | -0.001 | -0.2764 | No | ||
75 | IL1RN | 2370333 | 10145 | -0.005 | -0.2903 | No | ||
76 | RND1 | 5080300 | 10181 | -0.006 | -0.2922 | No | ||
77 | WNT10A | 2100706 | 10190 | -0.006 | -0.2926 | No | ||
78 | KLK9 | 4120164 | 10623 | -0.012 | -0.3159 | No | ||
79 | PTHLH | 5290739 | 10688 | -0.013 | -0.3193 | No | ||
80 | EHF | 4560088 | 10721 | -0.014 | -0.3209 | No | ||
81 | MOBKL2C | 2640088 3830017 | 10966 | -0.018 | -0.3341 | No | ||
82 | ALG6 | 4060131 | 11675 | -0.031 | -0.3722 | No | ||
83 | MITF | 380056 | 11690 | -0.031 | -0.3728 | No | ||
84 | BDNF | 2940128 3520368 | 11802 | -0.034 | -0.3786 | No | ||
85 | GNG4 | 2630600 | 11989 | -0.038 | -0.3885 | No | ||
86 | UBE2I | 2680056 6350446 | 12095 | -0.041 | -0.3939 | No | ||
87 | PAPPA | 4230463 | 12362 | -0.047 | -0.4081 | No | ||
88 | C1QL1 | 2030465 | 12473 | -0.050 | -0.4138 | No | ||
89 | GABRB1 | 6760193 | 12517 | -0.051 | -0.4158 | No | ||
90 | SEMA3B | 5570563 | 12573 | -0.052 | -0.4185 | No | ||
91 | GREM1 | 3940180 | 12587 | -0.052 | -0.4189 | No | ||
92 | IL23A | 6290044 | 12734 | -0.057 | -0.4264 | No | ||
93 | FGF1 | 4780435 5670601 | 12765 | -0.058 | -0.4277 | No | ||
94 | DCAMKL1 | 540095 2690092 | 12830 | -0.060 | -0.4308 | No | ||
95 | RFX5 | 5420128 | 12967 | -0.065 | -0.4378 | No | ||
96 | STAT6 | 1190010 5720019 | 12978 | -0.065 | -0.4380 | No | ||
97 | TBX20 | 2230279 4920102 6980020 | 13041 | -0.067 | -0.4410 | No | ||
98 | ERN1 | 2360403 | 13106 | -0.070 | -0.4440 | No | ||
99 | SOX5 | 2370576 2900167 3190128 5050528 | 13267 | -0.076 | -0.4522 | No | ||
100 | GATA4 | 1410215 2690609 | 13425 | -0.083 | -0.4603 | No | ||
101 | MAG | 2370037 | 13650 | -0.096 | -0.4718 | No | ||
102 | SP6 | 60484 510452 2690333 | 13741 | -0.101 | -0.4761 | No | ||
103 | TSLP | 730408 1990500 | 13858 | -0.110 | -0.4818 | No | ||
104 | BATF | 6760390 | 14101 | -0.128 | -0.4941 | No | ||
105 | GRIN2D | 6620372 | 14265 | -0.144 | -0.5021 | No | ||
106 | PCSK2 | 360017 430528 5900619 | 14291 | -0.146 | -0.5026 | No | ||
107 | ASCL3 | 4570484 | 14295 | -0.146 | -0.5019 | No | ||
108 | BIRC3 | 6550411 | 14393 | -0.156 | -0.5063 | No | ||
109 | DUSP22 | 4280010 5550546 | 14400 | -0.157 | -0.5057 | No | ||
110 | SIN3A | 2190121 | 14411 | -0.157 | -0.5053 | No | ||
111 | DDR1 | 2060044 5220180 | 14663 | -0.192 | -0.5178 | No | ||
112 | EBI3 | 5340300 | 14685 | -0.195 | -0.5178 | No | ||
113 | BLR1 | 1500300 5420017 | 14702 | -0.198 | -0.5175 | No | ||
114 | PPP1R13B | 4010605 4760181 | 14979 | -0.259 | -0.5309 | No | ||
115 | SLAMF8 | 1230048 | 15077 | -0.284 | -0.5345 | No | ||
116 | FUT7 | 2900736 | 15118 | -0.296 | -0.5350 | No | ||
117 | JAK3 | 70347 3290008 | 15141 | -0.301 | -0.5344 | No | ||
118 | ILK | 870601 4480180 | 15143 | -0.302 | -0.5327 | No | ||
119 | TCF1 | 5390022 | 15216 | -0.325 | -0.5347 | No | ||
120 | NLK | 2030010 2450041 | 15237 | -0.333 | -0.5338 | No | ||
121 | MSC | 5080139 | 15253 | -0.341 | -0.5326 | No | ||
122 | GADD45B | 2350408 | 15364 | -0.376 | -0.5364 | No | ||
123 | TRAF4 | 3060041 4920528 6980286 | 15390 | -0.388 | -0.5355 | No | ||
124 | LTA | 1740088 | 15843 | -0.586 | -0.5565 | No | ||
125 | HIVEP1 | 3850632 | 15928 | -0.631 | -0.5574 | No | ||
126 | NEK8 | 5700180 | 16008 | -0.678 | -0.5577 | No | ||
127 | PFN1 | 6130132 | 16033 | -0.689 | -0.5550 | No | ||
128 | ZIC4 | 1500082 | 16172 | -0.777 | -0.5579 | No | ||
129 | UBD | 5570632 | 16198 | -0.792 | -0.5546 | No | ||
130 | EDG5 | 2640300 | 16299 | -0.875 | -0.5549 | No | ||
131 | TOP1 | 770471 4060632 6650324 | 16388 | -0.933 | -0.5542 | No | ||
132 | ARHGEF2 | 3360577 | 16580 | -1.046 | -0.5585 | No | ||
133 | CHD4 | 5420059 6130338 6380717 | 16744 | -1.194 | -0.5603 | No | ||
134 | TNFRSF9 | 2510400 6650484 | 17001 | -1.453 | -0.5657 | No | ||
135 | RASSF2 | 2480079 5720546 | 17254 | -1.776 | -0.5690 | Yes | ||
136 | IL6ST | 5890047 | 17300 | -1.822 | -0.5607 | Yes | ||
137 | SOCS2 | 4760692 | 17316 | -1.839 | -0.5508 | Yes | ||
138 | NFKBIA | 1570152 | 17332 | -1.860 | -0.5407 | Yes | ||
139 | CENTB5 | 5690128 | 17336 | -1.865 | -0.5300 | Yes | ||
140 | GNB1 | 2120397 | 17416 | -2.005 | -0.5225 | Yes | ||
141 | RELB | 1400048 | 17503 | -2.129 | -0.5147 | Yes | ||
142 | EIF5A | 1500059 5290022 6370026 | 17614 | -2.334 | -0.5070 | Yes | ||
143 | NFKB2 | 2320670 | 17622 | -2.349 | -0.4937 | Yes | ||
144 | ICAM1 | 6980138 | 17701 | -2.507 | -0.4832 | Yes | ||
145 | TRIB2 | 4120605 | 17714 | -2.527 | -0.4691 | Yes | ||
146 | UACA | 1190725 | 17830 | -2.771 | -0.4591 | Yes | ||
147 | MMP9 | 580338 | 17831 | -2.773 | -0.4429 | Yes | ||
148 | XPO6 | 3940019 | 17891 | -2.889 | -0.4292 | Yes | ||
149 | RHOG | 6760575 | 17892 | -2.890 | -0.4122 | Yes | ||
150 | MAP3K11 | 7000039 | 17924 | -2.956 | -0.3966 | Yes | ||
151 | DUSP6 | 5910286 7100070 | 17982 | -3.129 | -0.3814 | Yes | ||
152 | IL4I1 | 3190161 | 18064 | -3.382 | -0.3660 | Yes | ||
153 | IL2RA | 6620450 | 18109 | -3.560 | -0.3476 | Yes | ||
154 | MRPS6 | 870164 | 18143 | -3.677 | -0.3278 | Yes | ||
155 | ATP1B1 | 3130594 | 18145 | -3.686 | -0.3063 | Yes | ||
156 | ZNRF1 | 70592 | 18344 | -4.665 | -0.2898 | Yes | ||
157 | USP52 | 3710215 6380133 | 18364 | -4.798 | -0.2627 | Yes | ||
158 | LTB | 3990672 | 18503 | -6.099 | -0.2345 | Yes | ||
159 | MAP4K2 | 4200037 | 18533 | -6.506 | -0.1980 | Yes | ||
160 | CCL5 | 3710397 | 18577 | -7.590 | -0.1559 | Yes | ||
161 | SMOC1 | 840039 | 18592 | -8.434 | -0.1073 | Yes | ||
162 | FBXL12 | 2230040 3520008 | 18605 | -9.071 | -0.0549 | Yes | ||
163 | TNIP1 | 2510279 5900041 6510435 | 18615 | -9.474 | 0.0001 | Yes |