Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$NFKB_C |
Enrichment Score (ES) | -0.5904009 |
Normalized Enrichment Score (NES) | -1.6397346 |
Nominal p-value | 0.0 |
FDR q-value | 0.14246717 |
FWER p-Value | 0.168 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PCBP4 | 6350722 | 270 | 4.138 | 0.0074 | No | ||
2 | TCEA2 | 6370546 | 518 | 3.213 | 0.0112 | No | ||
3 | NFKBIB | 2260167 | 687 | 2.854 | 0.0173 | No | ||
4 | BMF | 610102 | 745 | 2.730 | 0.0288 | No | ||
5 | ARHGAP8 | 380333 5390487 | 853 | 2.517 | 0.0364 | No | ||
6 | VCAM1 | 2900450 | 1226 | 2.029 | 0.0271 | No | ||
7 | PRKCD | 770592 | 1385 | 1.829 | 0.0283 | No | ||
8 | CDC37 | 2570537 | 1463 | 1.724 | 0.0333 | No | ||
9 | AMOTL1 | 380279 | 1502 | 1.678 | 0.0402 | No | ||
10 | BHLHB2 | 7040603 | 1527 | 1.650 | 0.0477 | No | ||
11 | ENO3 | 5270136 | 1602 | 1.577 | 0.0521 | No | ||
12 | SMARCAD1 | 5390619 | 1756 | 1.440 | 0.0515 | No | ||
13 | RAD18 | 5670372 | 1808 | 1.391 | 0.0561 | No | ||
14 | LASP1 | 1690528 2190341 6420341 | 1967 | 1.247 | 0.0542 | No | ||
15 | SEC14L2 | 2640370 | 2037 | 1.191 | 0.0568 | No | ||
16 | CYLD | 6590079 | 2137 | 1.107 | 0.0574 | No | ||
17 | NDRG2 | 450403 | 2230 | 1.033 | 0.0579 | No | ||
18 | SNX15 | 1240348 6770082 | 2400 | 0.970 | 0.0539 | No | ||
19 | TYRO3 | 3130193 | 2436 | 0.948 | 0.0571 | No | ||
20 | ANP32A | 510044 1580095 2680037 | 2763 | 0.738 | 0.0433 | No | ||
21 | LAMB3 | 7100301 | 2890 | 0.676 | 0.0401 | No | ||
22 | BCKDK | 1940601 3990600 | 2951 | 0.649 | 0.0403 | No | ||
23 | ZADH2 | 520438 | 2984 | 0.626 | 0.0419 | No | ||
24 | CDC14A | 4050132 | 3165 | 0.538 | 0.0350 | No | ||
25 | IL27RA | 940093 | 3218 | 0.518 | 0.0349 | No | ||
26 | WRN | 540687 1240093 | 3398 | 0.449 | 0.0276 | No | ||
27 | EGR3 | 6940128 | 3667 | 0.363 | 0.0150 | No | ||
28 | RAP2C | 1690132 | 3675 | 0.360 | 0.0166 | No | ||
29 | ASH1L | 2510402 5360687 6650685 | 4018 | 0.274 | -0.0005 | No | ||
30 | CDK6 | 4920253 | 4019 | 0.273 | 0.0009 | No | ||
31 | GPHN | 3290195 3840121 | 4117 | 0.252 | -0.0030 | No | ||
32 | TNFSF18 | 1990458 2850520 | 4193 | 0.237 | -0.0058 | No | ||
33 | EGF | 5220154 | 4215 | 0.234 | -0.0057 | No | ||
34 | CLCN1 | 840161 | 4346 | 0.214 | -0.0116 | No | ||
35 | SESN2 | 2370019 | 4638 | 0.173 | -0.0265 | No | ||
36 | LRRFIP2 | 670575 730152 6590438 | 4662 | 0.171 | -0.0268 | No | ||
37 | CTGF | 4540577 | 4683 | 0.168 | -0.0270 | No | ||
38 | NFAT5 | 2510411 5890195 6550152 | 4702 | 0.165 | -0.0271 | No | ||
39 | SNAP25 | 360520 | 4856 | 0.149 | -0.0346 | No | ||
40 | FTHL17 | 6550193 | 4900 | 0.144 | -0.0362 | No | ||
41 | BAI2 | 380632 630113 6650170 | 4945 | 0.141 | -0.0378 | No | ||
42 | PLA1A | 4590040 6100204 | 4969 | 0.139 | -0.0383 | No | ||
43 | TRIM47 | 5080717 | 4971 | 0.138 | -0.0376 | No | ||
44 | PPP3CA | 4760332 6760092 | 5002 | 0.136 | -0.0385 | No | ||
45 | SLC6A12 | 3170685 | 5152 | 0.123 | -0.0459 | No | ||
46 | GRK5 | 1940348 4670053 | 5226 | 0.118 | -0.0493 | No | ||
47 | IL13 | 7040021 | 5348 | 0.110 | -0.0552 | No | ||
48 | BCL3 | 3990440 | 5360 | 0.110 | -0.0553 | No | ||
49 | IFNB1 | 1400142 | 5467 | 0.103 | -0.0605 | No | ||
50 | HSD3B7 | 1410129 | 5529 | 0.100 | -0.0632 | No | ||
51 | DAP3 | 1660528 2120039 5420593 | 5537 | 0.099 | -0.0631 | No | ||
52 | RALGDS | 430463 | 5823 | 0.085 | -0.0781 | No | ||
53 | PTGS2 | 2510301 3170369 | 6240 | 0.070 | -0.1003 | No | ||
54 | SIRT2 | 630494 | 6263 | 0.069 | -0.1011 | No | ||
55 | MLLT6 | 3870168 | 6273 | 0.069 | -0.1012 | No | ||
56 | PTGES | 1690075 | 6418 | 0.064 | -0.1087 | No | ||
57 | SMPD3 | 520164 | 6443 | 0.064 | -0.1097 | No | ||
58 | EFNA3 | 6370390 | 6654 | 0.057 | -0.1208 | No | ||
59 | DACH2 | 460605 1500253 | 6775 | 0.053 | -0.1270 | No | ||
60 | PHF6 | 3120632 3990041 | 6828 | 0.052 | -0.1295 | No | ||
61 | ECT2 | 3830086 | 6972 | 0.048 | -0.1370 | No | ||
62 | RIN2 | 2450184 | 7078 | 0.046 | -0.1425 | No | ||
63 | LIN28 | 6590672 | 7153 | 0.044 | -0.1463 | No | ||
64 | DNAJA1 | 1660010 2320358 6840136 | 7463 | 0.039 | -0.1628 | No | ||
65 | PTPRJ | 4010707 | 7521 | 0.037 | -0.1657 | No | ||
66 | MAP3K13 | 3190017 | 7591 | 0.036 | -0.1693 | No | ||
67 | IL2 | 1770725 | 8133 | 0.026 | -0.1985 | No | ||
68 | FOXD3 | 6550156 | 8196 | 0.025 | -0.2017 | No | ||
69 | CUEDC1 | 1660463 | 8292 | 0.023 | -0.2067 | No | ||
70 | SOX10 | 6200538 | 8490 | 0.020 | -0.2173 | No | ||
71 | SOX3 | 4570537 | 8772 | 0.016 | -0.2325 | No | ||
72 | FGF17 | 3130022 | 8847 | 0.014 | -0.2364 | No | ||
73 | IL1A | 3610056 | 8909 | 0.014 | -0.2397 | No | ||
74 | MSX1 | 2650309 | 8971 | 0.012 | -0.2429 | No | ||
75 | TNFSF15 | 360341 | 9124 | 0.010 | -0.2511 | No | ||
76 | VNN3 | 730053 4610609 | 9252 | 0.008 | -0.2579 | No | ||
77 | GNAO1 | 2510292 6590487 | 9288 | 0.008 | -0.2598 | No | ||
78 | TNR | 1340541 | 9340 | 0.007 | -0.2625 | No | ||
79 | CXCL10 | 2450408 | 9426 | 0.006 | -0.2671 | No | ||
80 | IER5 | 2350575 | 9837 | -0.001 | -0.2894 | No | ||
81 | IL27 | 1990324 | 9887 | -0.001 | -0.2920 | No | ||
82 | HOXA11 | 6980133 | 9947 | -0.002 | -0.2952 | No | ||
83 | ARHGAP5 | 2510619 3360035 | 9991 | -0.003 | -0.2975 | No | ||
84 | HOXB6 | 4210739 | 10098 | -0.005 | -0.3032 | No | ||
85 | IL1RN | 2370333 | 10145 | -0.005 | -0.3057 | No | ||
86 | RND1 | 5080300 | 10181 | -0.006 | -0.3076 | No | ||
87 | WNT10A | 2100706 | 10190 | -0.006 | -0.3080 | No | ||
88 | GABPB2 | 6130450 7050735 | 10310 | -0.008 | -0.3144 | No | ||
89 | PTHLH | 5290739 | 10688 | -0.013 | -0.3348 | No | ||
90 | EHF | 4560088 | 10721 | -0.014 | -0.3364 | No | ||
91 | RAB10 | 2360008 5890020 | 10753 | -0.015 | -0.3380 | No | ||
92 | JPH3 | 780397 | 10766 | -0.015 | -0.3386 | No | ||
93 | MOBKL2C | 2640088 3830017 | 10966 | -0.018 | -0.3493 | No | ||
94 | NUP153 | 7000452 | 11304 | -0.024 | -0.3675 | No | ||
95 | ALG6 | 4060131 | 11675 | -0.031 | -0.3874 | No | ||
96 | LYPLA2 | 1500112 | 11697 | -0.032 | -0.3884 | No | ||
97 | BDNF | 2940128 3520368 | 11802 | -0.034 | -0.3938 | No | ||
98 | GNG4 | 2630600 | 11989 | -0.038 | -0.4037 | No | ||
99 | CCL22 | 6380086 | 11991 | -0.038 | -0.4036 | No | ||
100 | UBE2I | 2680056 6350446 | 12095 | -0.041 | -0.4089 | No | ||
101 | HOXB9 | 2640687 | 12334 | -0.046 | -0.4216 | No | ||
102 | PAPPA | 4230463 | 12362 | -0.047 | -0.4228 | No | ||
103 | C1QL1 | 2030465 | 12473 | -0.050 | -0.4285 | No | ||
104 | TSNAXIP1 | 1770270 6180577 | 12501 | -0.050 | -0.4297 | No | ||
105 | SEMA3B | 5570563 | 12573 | -0.052 | -0.4333 | No | ||
106 | IL23A | 6290044 | 12734 | -0.057 | -0.4417 | No | ||
107 | FGF1 | 4780435 5670601 | 12765 | -0.058 | -0.4430 | No | ||
108 | DCAMKL1 | 540095 2690092 | 12830 | -0.060 | -0.4461 | No | ||
109 | STAT6 | 1190010 5720019 | 12978 | -0.065 | -0.4538 | No | ||
110 | SOX5 | 2370576 2900167 3190128 5050528 | 13267 | -0.076 | -0.4690 | No | ||
111 | GATA4 | 1410215 2690609 | 13425 | -0.083 | -0.4771 | No | ||
112 | ARPC5 | 1740411 3450300 | 13646 | -0.096 | -0.4885 | No | ||
113 | MAG | 2370037 | 13650 | -0.096 | -0.4881 | No | ||
114 | SP6 | 60484 510452 2690333 | 13741 | -0.101 | -0.4925 | No | ||
115 | COL11A2 | 5130341 | 13822 | -0.107 | -0.4962 | No | ||
116 | TSLP | 730408 1990500 | 13858 | -0.110 | -0.4976 | No | ||
117 | FOS | 1850315 | 14050 | -0.124 | -0.5073 | No | ||
118 | SLC34A3 | 2230242 | 14234 | -0.141 | -0.5164 | No | ||
119 | RGL1 | 1500097 6900450 | 14239 | -0.141 | -0.5159 | No | ||
120 | GRIN2D | 6620372 | 14265 | -0.144 | -0.5165 | No | ||
121 | FOXA3 | 2680121 | 14278 | -0.145 | -0.5164 | No | ||
122 | PCSK2 | 360017 430528 5900619 | 14291 | -0.146 | -0.5162 | No | ||
123 | ASCL3 | 4570484 | 14295 | -0.146 | -0.5156 | No | ||
124 | DUSP22 | 4280010 5550546 | 14400 | -0.157 | -0.5204 | No | ||
125 | SIN3A | 2190121 | 14411 | -0.157 | -0.5201 | No | ||
126 | GNA13 | 4590102 | 14413 | -0.158 | -0.5193 | No | ||
127 | LCAT | 6400441 | 14446 | -0.161 | -0.5202 | No | ||
128 | CDH5 | 5340487 | 14614 | -0.185 | -0.5283 | No | ||
129 | PIGC | 5690377 | 14659 | -0.191 | -0.5297 | No | ||
130 | DDR1 | 2060044 5220180 | 14663 | -0.192 | -0.5288 | No | ||
131 | BLR1 | 1500300 5420017 | 14702 | -0.198 | -0.5298 | No | ||
132 | PPP2R5E | 70671 2120056 | 14716 | -0.200 | -0.5295 | No | ||
133 | ITGB4 | 1740021 3840482 | 14739 | -0.205 | -0.5296 | No | ||
134 | PPP1R13B | 4010605 4760181 | 14979 | -0.259 | -0.5411 | No | ||
135 | SLAMF8 | 1230048 | 15077 | -0.284 | -0.5449 | No | ||
136 | FUT7 | 2900736 | 15118 | -0.296 | -0.5455 | No | ||
137 | JAK3 | 70347 3290008 | 15141 | -0.301 | -0.5451 | No | ||
138 | NLK | 2030010 2450041 | 15237 | -0.333 | -0.5484 | No | ||
139 | MSC | 5080139 | 15253 | -0.341 | -0.5474 | No | ||
140 | CHX10 | 3830184 | 15327 | -0.365 | -0.5494 | No | ||
141 | GADD45B | 2350408 | 15364 | -0.376 | -0.5494 | No | ||
142 | IL18R1 | 270546 | 15526 | -0.442 | -0.5558 | No | ||
143 | FOXD2 | 4210035 | 15585 | -0.467 | -0.5564 | No | ||
144 | TAL1 | 7040239 | 15617 | -0.479 | -0.5555 | No | ||
145 | MNT | 4920575 | 15674 | -0.510 | -0.5559 | No | ||
146 | MAP3K8 | 2940286 | 15987 | -0.666 | -0.5692 | No | ||
147 | PFN1 | 6130132 | 16033 | -0.689 | -0.5680 | No | ||
148 | EDG5 | 2640300 | 16299 | -0.875 | -0.5777 | No | ||
149 | TOP1 | 770471 4060632 6650324 | 16388 | -0.933 | -0.5775 | No | ||
150 | CGGBP1 | 4810053 | 16516 | -1.010 | -0.5790 | No | ||
151 | ARHGEF2 | 3360577 | 16580 | -1.046 | -0.5768 | No | ||
152 | FLI1 | 3990142 | 16600 | -1.061 | -0.5722 | No | ||
153 | CHD4 | 5420059 6130338 6380717 | 16744 | -1.194 | -0.5736 | No | ||
154 | ZHX2 | 2900452 | 17055 | -1.511 | -0.5823 | Yes | ||
155 | IRF1 | 2340152 3450592 6290121 6980577 | 17156 | -1.653 | -0.5789 | Yes | ||
156 | RHOA | 580142 5900131 5340450 | 17225 | -1.731 | -0.5734 | Yes | ||
157 | PURG | 1190593 | 17262 | -1.785 | -0.5658 | Yes | ||
158 | BCL2L1 | 1580452 4200152 5420484 | 17267 | -1.792 | -0.5565 | Yes | ||
159 | SOCS2 | 4760692 | 17316 | -1.839 | -0.5492 | Yes | ||
160 | NFKBIA | 1570152 | 17332 | -1.860 | -0.5401 | Yes | ||
161 | CENTB5 | 5690128 | 17336 | -1.865 | -0.5303 | Yes | ||
162 | BCL11A | 6860369 | 17349 | -1.884 | -0.5209 | Yes | ||
163 | EIF5A | 1500059 5290022 6370026 | 17614 | -2.334 | -0.5228 | Yes | ||
164 | NFKB2 | 2320670 | 17622 | -2.349 | -0.5106 | Yes | ||
165 | ICAM1 | 6980138 | 17701 | -2.507 | -0.5015 | Yes | ||
166 | TRIB2 | 4120605 | 17714 | -2.527 | -0.4886 | Yes | ||
167 | UACA | 1190725 | 17830 | -2.771 | -0.4801 | Yes | ||
168 | HCFC1 | 2260008 | 17838 | -2.780 | -0.4656 | Yes | ||
169 | FOXJ2 | 2450441 | 17877 | -2.870 | -0.4524 | Yes | ||
170 | XPO6 | 3940019 | 17891 | -2.889 | -0.4377 | Yes | ||
171 | RHOG | 6760575 | 17892 | -2.890 | -0.4222 | Yes | ||
172 | LCN2 | 2510112 | 17907 | -2.924 | -0.4074 | Yes | ||
173 | IL4I1 | 3190161 | 18064 | -3.382 | -0.3978 | Yes | ||
174 | TCTA | 2680687 | 18070 | -3.421 | -0.3798 | Yes | ||
175 | IL2RA | 6620450 | 18109 | -3.560 | -0.3629 | Yes | ||
176 | MRPS6 | 870164 | 18143 | -3.677 | -0.3450 | Yes | ||
177 | RANBP10 | 2340184 | 18203 | -3.900 | -0.3274 | Yes | ||
178 | TAZ | 7100193 | 18300 | -4.463 | -0.3088 | Yes | ||
179 | RORC | 1740121 | 18360 | -4.769 | -0.2865 | Yes | ||
180 | USP52 | 3710215 6380133 | 18364 | -4.798 | -0.2611 | Yes | ||
181 | EPHB6 | 5860128 | 18449 | -5.553 | -0.2360 | Yes | ||
182 | EGR2 | 3800403 | 18471 | -5.748 | -0.2065 | Yes | ||
183 | LTB | 3990672 | 18503 | -6.099 | -0.1756 | Yes | ||
184 | CCL5 | 3710397 | 18577 | -7.590 | -0.1390 | Yes | ||
185 | SMOC1 | 840039 | 18592 | -8.434 | -0.0948 | Yes | ||
186 | S100A10 | 6350010 | 18596 | -8.500 | -0.0495 | Yes | ||
187 | TNIP1 | 2510279 5900041 6510435 | 18615 | -9.474 | 0.0001 | Yes |