Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q3 |
Enrichment Score (ES) | 0.49429563 |
Normalized Enrichment Score (NES) | 1.3512651 |
Nominal p-value | 0.018828452 |
FDR q-value | 0.57933146 |
FWER p-Value | 0.999 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SHMT1 | 5900132 | 112 | 5.195 | 0.0318 | Yes | ||
2 | TFRC | 4050551 | 213 | 4.421 | 0.0587 | Yes | ||
3 | IMPDH2 | 5220138 | 294 | 4.012 | 0.0836 | Yes | ||
4 | RFC1 | 1190673 | 497 | 3.258 | 0.0965 | Yes | ||
5 | UNG | 3130110 6100364 | 564 | 3.124 | 0.1157 | Yes | ||
6 | HNRPA1 | 4670398 5050687 | 565 | 3.124 | 0.1385 | Yes | ||
7 | RBBP7 | 430113 450450 2370309 | 566 | 3.123 | 0.1613 | Yes | ||
8 | SLC25A3 | 670112 | 631 | 2.954 | 0.1794 | Yes | ||
9 | LIG1 | 1980438 4540112 5570609 | 654 | 2.897 | 0.1993 | Yes | ||
10 | E2F1 | 5360093 | 847 | 2.525 | 0.2073 | Yes | ||
11 | NCL | 2360463 4540279 | 893 | 2.461 | 0.2229 | Yes | ||
12 | MCM3 | 5570068 | 925 | 2.409 | 0.2388 | Yes | ||
13 | ABCF2 | 630040 3140035 6450601 | 979 | 2.325 | 0.2528 | Yes | ||
14 | NASP | 2260139 2940369 5130707 | 1015 | 2.282 | 0.2676 | Yes | ||
15 | PPP1R8 | 6290292 | 1024 | 2.270 | 0.2837 | Yes | ||
16 | MCM4 | 2760673 5420711 | 1104 | 2.179 | 0.2953 | Yes | ||
17 | SLC38A1 | 520465 | 1224 | 2.031 | 0.3037 | Yes | ||
18 | GCH1 | 670364 6550358 | 1233 | 2.020 | 0.3180 | Yes | ||
19 | PIAS1 | 5340301 | 1323 | 1.909 | 0.3271 | Yes | ||
20 | MCM6 | 60092 540181 6510110 | 1326 | 1.907 | 0.3409 | Yes | ||
21 | OLFML3 | 7100463 | 1369 | 1.850 | 0.3522 | Yes | ||
22 | AP4M1 | 70609 3440128 | 1375 | 1.841 | 0.3653 | Yes | ||
23 | STMN1 | 1990717 | 1415 | 1.783 | 0.3762 | Yes | ||
24 | HMGN2 | 3140091 | 1422 | 1.774 | 0.3888 | Yes | ||
25 | APRIN | 2810050 | 1515 | 1.662 | 0.3960 | Yes | ||
26 | POLA2 | 940519 | 1657 | 1.535 | 0.3996 | Yes | ||
27 | RBBP4 | 6650528 | 1683 | 1.518 | 0.4093 | Yes | ||
28 | PRPS1 | 6350129 | 1749 | 1.447 | 0.4163 | Yes | ||
29 | CDC25A | 3800184 | 1784 | 1.416 | 0.4248 | Yes | ||
30 | TCP1 | 2450100 5130524 | 1856 | 1.357 | 0.4309 | Yes | ||
31 | ZCCHC8 | 2260332 2350487 | 1875 | 1.335 | 0.4396 | Yes | ||
32 | HIST1H2BK | 6130433 | 1965 | 1.250 | 0.4439 | Yes | ||
33 | LASP1 | 1690528 2190341 6420341 | 1967 | 1.247 | 0.4530 | Yes | ||
34 | DNAJC11 | 360465 3390215 | 2110 | 1.132 | 0.4536 | Yes | ||
35 | KPNB1 | 1690138 | 2147 | 1.097 | 0.4596 | Yes | ||
36 | DLST | 2320722 | 2187 | 1.062 | 0.4652 | Yes | ||
37 | CDCA7 | 3060097 | 2203 | 1.051 | 0.4721 | Yes | ||
38 | SFRS2 | 50707 380593 | 2242 | 1.028 | 0.4775 | Yes | ||
39 | CDC6 | 4570296 5360600 | 2290 | 1.012 | 0.4824 | Yes | ||
40 | MCM2 | 5050139 | 2398 | 0.971 | 0.4837 | Yes | ||
41 | TBX6 | 4730139 6840647 | 2460 | 0.935 | 0.4872 | Yes | ||
42 | BAT3 | 1990594 | 2530 | 0.884 | 0.4899 | Yes | ||
43 | MCM7 | 3290292 5220056 | 2567 | 0.868 | 0.4943 | Yes | ||
44 | GMNN | 2630148 | 2690 | 0.783 | 0.4934 | No | ||
45 | KCNA1 | 2030594 | 2898 | 0.672 | 0.4871 | No | ||
46 | PHF15 | 6550066 6860673 | 2930 | 0.658 | 0.4902 | No | ||
47 | MRPL18 | 6560341 | 3113 | 0.564 | 0.4845 | No | ||
48 | H2AFZ | 1470168 | 3180 | 0.533 | 0.4848 | No | ||
49 | ADAMTS2 | 2650025 6370133 6840670 | 3185 | 0.531 | 0.4885 | No | ||
50 | EPHB2 | 1090288 1410377 2100541 | 3425 | 0.440 | 0.4787 | No | ||
51 | KLF4 | 1850022 3830239 5570750 | 3574 | 0.389 | 0.4736 | No | ||
52 | SSBP3 | 870717 1050377 7040551 | 3708 | 0.350 | 0.4689 | No | ||
53 | E2F3 | 50162 460180 | 3726 | 0.343 | 0.4705 | No | ||
54 | PRKDC | 1400072 4230541 | 3789 | 0.325 | 0.4695 | No | ||
55 | CNOT3 | 130519 4480292 1990609 | 4177 | 0.240 | 0.4503 | No | ||
56 | SNPH | 2680484 | 4187 | 0.239 | 0.4516 | No | ||
57 | PAQR4 | 730736 | 4223 | 0.232 | 0.4514 | No | ||
58 | UFD1L | 870020 | 4242 | 0.231 | 0.4521 | No | ||
59 | TBX3 | 2570672 | 4401 | 0.204 | 0.4450 | No | ||
60 | CPNE5 | 6380673 | 4418 | 0.202 | 0.4456 | No | ||
61 | RHD | 4050168 | 4421 | 0.202 | 0.4470 | No | ||
62 | STAG2 | 4540132 | 4512 | 0.189 | 0.4435 | No | ||
63 | BARHL1 | 4210113 | 4630 | 0.174 | 0.4384 | No | ||
64 | TRIM47 | 5080717 | 4971 | 0.138 | 0.4210 | No | ||
65 | NDUFA11 | 3780333 | 5040 | 0.133 | 0.4183 | No | ||
66 | EZH2 | 6130605 6380524 | 5373 | 0.109 | 0.4011 | No | ||
67 | ADCY8 | 6760519 | 5434 | 0.105 | 0.3987 | No | ||
68 | HS6ST3 | 5910138 | 6151 | 0.073 | 0.3604 | No | ||
69 | CTCF | 5340017 | 6156 | 0.073 | 0.3607 | No | ||
70 | PCSK1 | 2350148 | 6244 | 0.070 | 0.3565 | No | ||
71 | JPH1 | 610739 | 6264 | 0.069 | 0.3560 | No | ||
72 | SLC6A4 | 2230372 | 6505 | 0.062 | 0.3435 | No | ||
73 | KCND2 | 1170128 2100112 | 6880 | 0.051 | 0.3236 | No | ||
74 | ARHGAP6 | 2060121 | 6942 | 0.049 | 0.3207 | No | ||
75 | SFRS1 | 2360440 | 7351 | 0.041 | 0.2989 | No | ||
76 | FMO4 | 360735 | 7638 | 0.035 | 0.2836 | No | ||
77 | WEE1 | 3390070 | 7693 | 0.034 | 0.2810 | No | ||
78 | SMAD6 | 870504 | 7712 | 0.033 | 0.2802 | No | ||
79 | ASCL1 | 6650100 | 7763 | 0.033 | 0.2778 | No | ||
80 | PODN | 3710068 | 7874 | 0.030 | 0.2720 | No | ||
81 | HNRPD | 4120021 | 7929 | 0.029 | 0.2693 | No | ||
82 | ATRX | 2340039 3610132 4210373 | 7958 | 0.029 | 0.2680 | No | ||
83 | ERBB2IP | 580253 1090672 | 7997 | 0.028 | 0.2662 | No | ||
84 | GRIK2 | 4610164 | 8112 | 0.026 | 0.2602 | No | ||
85 | PAPOLG | 2470400 | 8120 | 0.026 | 0.2600 | No | ||
86 | STK35 | 2360121 | 8335 | 0.023 | 0.2486 | No | ||
87 | POLE2 | 6110041 | 8698 | 0.017 | 0.2291 | No | ||
88 | HTF9C | 3190048 4120132 | 8805 | 0.015 | 0.2235 | No | ||
89 | AP1S2 | 780279 4280707 | 9238 | 0.008 | 0.2001 | No | ||
90 | NPR3 | 1580239 | 9257 | 0.008 | 0.1992 | No | ||
91 | NRP2 | 4070400 5860041 6650446 | 9923 | -0.002 | 0.1632 | No | ||
92 | TOPBP1 | 6020333 | 10057 | -0.004 | 0.1561 | No | ||
93 | SEZ6 | 3450722 | 10152 | -0.006 | 0.1510 | No | ||
94 | HIST1H1D | 3440446 | 10301 | -0.008 | 0.1430 | No | ||
95 | DMD | 1740041 3990332 | 11254 | -0.023 | 0.0917 | No | ||
96 | FBXO5 | 2630551 | 11285 | -0.024 | 0.0902 | No | ||
97 | IPO7 | 2190746 | 11290 | -0.024 | 0.0902 | No | ||
98 | NUP153 | 7000452 | 11304 | -0.024 | 0.0897 | No | ||
99 | ATAD2 | 870242 2260687 | 11471 | -0.027 | 0.0809 | No | ||
100 | RAD51 | 6110450 6980280 | 11523 | -0.028 | 0.0783 | No | ||
101 | PEG3 | 3710020 | 11774 | -0.033 | 0.0650 | No | ||
102 | EPHB1 | 4610056 | 11791 | -0.033 | 0.0644 | No | ||
103 | TREX2 | 4920707 | 12076 | -0.040 | 0.0493 | No | ||
104 | CASP8AP2 | 5910593 | 12484 | -0.050 | 0.0276 | No | ||
105 | MEIS1 | 1400575 | 12643 | -0.054 | 0.0195 | No | ||
106 | ONECUT1 | 6450136 | 12677 | -0.055 | 0.0181 | No | ||
107 | SEMA5A | 6200110 6520435 | 13138 | -0.071 | -0.0063 | No | ||
108 | UXT | 110019 5080066 | 13171 | -0.072 | -0.0075 | No | ||
109 | CACNA1G | 3060161 4810706 5550722 | 13305 | -0.078 | -0.0141 | No | ||
110 | LHX5 | 2350097 | 13388 | -0.081 | -0.0180 | No | ||
111 | CBX5 | 3830072 6290167 | 13495 | -0.086 | -0.0231 | No | ||
112 | CLTA | 450010 | 13554 | -0.090 | -0.0256 | No | ||
113 | SALL1 | 5420020 7050195 | 13724 | -0.100 | -0.0340 | No | ||
114 | NOL4 | 5050446 5360519 | 14076 | -0.126 | -0.0521 | No | ||
115 | ARID4A | 520156 1050707 | 14193 | -0.137 | -0.0574 | No | ||
116 | MCM8 | 6130743 | 14267 | -0.144 | -0.0603 | No | ||
117 | ATE1 | 290491 6940722 | 14402 | -0.157 | -0.0664 | No | ||
118 | DPYSL2 | 2100427 3130112 5700324 | 14617 | -0.185 | -0.0766 | No | ||
119 | MDGA1 | 1170139 | 14732 | -0.203 | -0.0813 | No | ||
120 | HIST1H2AH | 3710333 | 15108 | -0.294 | -0.0995 | No | ||
121 | CTDSP1 | 6650215 6940731 | 15116 | -0.295 | -0.0977 | No | ||
122 | PVRL1 | 2570167 5220519 5890500 3190309 | 15123 | -0.296 | -0.0958 | No | ||
123 | INSM1 | 3450671 | 15220 | -0.328 | -0.0986 | No | ||
124 | CDC45L | 70537 3130114 | 15261 | -0.345 | -0.0983 | No | ||
125 | RANBP1 | 430215 1090180 | 15436 | -0.407 | -0.1047 | No | ||
126 | DNMT1 | 2260097 | 15653 | -0.498 | -0.1128 | No | ||
127 | E2F7 | 4200056 | 15794 | -0.566 | -0.1163 | No | ||
128 | DDB2 | 3520341 4610168 4850184 4920717 | 15817 | -0.577 | -0.1132 | No | ||
129 | KLF5 | 3840348 | 16019 | -0.684 | -0.1191 | No | ||
130 | MAT2A | 4070026 4730079 6020280 | 16205 | -0.802 | -0.1233 | No | ||
131 | PCNA | 940754 | 16217 | -0.813 | -0.1180 | No | ||
132 | ING3 | 110438 2060390 | 16314 | -0.886 | -0.1167 | No | ||
133 | PLK4 | 430162 5720110 | 16542 | -1.027 | -0.1215 | No | ||
134 | FLI1 | 3990142 | 16600 | -1.061 | -0.1168 | No | ||
135 | USP1 | 2760541 5690438 6220673 | 16673 | -1.126 | -0.1125 | No | ||
136 | PCSK4 | 130687 670711 3170075 6400411 | 16718 | -1.170 | -0.1064 | No | ||
137 | ORC1L | 2370328 6110390 | 16727 | -1.176 | -0.0982 | No | ||
138 | MAZ | 3360121 6940750 | 16753 | -1.204 | -0.0908 | No | ||
139 | PPP1CC | 6380300 2510647 | 17295 | -1.817 | -0.1068 | No | ||
140 | SLC25A14 | 4760180 | 17344 | -1.873 | -0.0958 | No | ||
141 | PIM1 | 630047 | 17549 | -2.218 | -0.0906 | No | ||
142 | PHF12 | 870400 3130687 | 17759 | -2.611 | -0.0829 | No | ||
143 | PHF13 | 450435 | 17874 | -2.865 | -0.0682 | No | ||
144 | SYT11 | 630433 | 18039 | -3.311 | -0.0529 | No | ||
145 | RAB11B | 3990609 | 18059 | -3.370 | -0.0293 | No | ||
146 | MXD3 | 6220014 | 18082 | -3.462 | -0.0053 | No | ||
147 | DCK | 6900411 | 18345 | -4.675 | 0.0147 | No |