Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$ARNT_01 |
Enrichment Score (ES) | 0.4579964 |
Normalized Enrichment Score (NES) | 1.2677191 |
Nominal p-value | 0.028888889 |
FDR q-value | 0.8302674 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | VARS2 | 1410017 3800114 4210270 | 38 | 6.639 | 0.0314 | Yes | ||
2 | SNX8 | 3450315 | 65 | 5.832 | 0.0594 | Yes | ||
3 | IFRD2 | 4150110 | 77 | 5.595 | 0.0870 | Yes | ||
4 | SHMT1 | 5900132 | 112 | 5.195 | 0.1114 | Yes | ||
5 | EIF4B | 5390563 5270577 | 144 | 4.909 | 0.1344 | Yes | ||
6 | AATF | 5220575 | 212 | 4.422 | 0.1531 | Yes | ||
7 | SLC39A11 | 5860687 | 233 | 4.315 | 0.1738 | Yes | ||
8 | NUDC | 4780025 | 234 | 4.307 | 0.1955 | Yes | ||
9 | QTRT1 | 1340162 | 242 | 4.267 | 0.2166 | Yes | ||
10 | PPAT | 1980019 | 255 | 4.206 | 0.2372 | Yes | ||
11 | DDX3X | 2190020 | 355 | 3.736 | 0.2506 | Yes | ||
12 | VPS16 | 430064 3390041 6860301 | 448 | 3.424 | 0.2629 | Yes | ||
13 | AKAP12 | 1450739 | 474 | 3.321 | 0.2783 | Yes | ||
14 | PSME3 | 2810537 | 487 | 3.284 | 0.2942 | Yes | ||
15 | CLN3 | 780368 | 562 | 3.127 | 0.3060 | Yes | ||
16 | HNRPA1 | 4670398 5050687 | 565 | 3.124 | 0.3216 | Yes | ||
17 | PAICS | 610142 | 608 | 3.017 | 0.3345 | Yes | ||
18 | EIF2C2 | 770451 | 614 | 3.009 | 0.3494 | Yes | ||
19 | NR1D1 | 2360471 770746 6590204 | 825 | 2.570 | 0.3510 | Yes | ||
20 | CCAR1 | 3190092 | 832 | 2.558 | 0.3636 | Yes | ||
21 | UBE4B | 780008 3610154 | 870 | 2.501 | 0.3742 | Yes | ||
22 | PER1 | 3290315 | 1057 | 2.234 | 0.3754 | Yes | ||
23 | HOXB4 | 540131 | 1086 | 2.203 | 0.3849 | Yes | ||
24 | COMMD3 | 2510259 | 1097 | 2.185 | 0.3954 | Yes | ||
25 | OPRS1 | 6130128 6290717 | 1219 | 2.040 | 0.3991 | Yes | ||
26 | PPRC1 | 1740441 | 1228 | 2.028 | 0.4089 | Yes | ||
27 | PPP1R1B | 5290403 5550324 | 1229 | 2.027 | 0.4192 | Yes | ||
28 | STMN1 | 1990717 | 1415 | 1.783 | 0.4181 | Yes | ||
29 | HMGN2 | 3140091 | 1422 | 1.774 | 0.4267 | Yes | ||
30 | ATP6V1C1 | 2690324 5220528 | 1548 | 1.632 | 0.4282 | Yes | ||
31 | CD164 | 3830594 | 1626 | 1.561 | 0.4319 | Yes | ||
32 | COPS7A | 3940458 7000022 | 1641 | 1.544 | 0.4389 | Yes | ||
33 | BOK | 1170373 5860446 | 1679 | 1.519 | 0.4445 | Yes | ||
34 | RHEBL1 | 2810576 | 1695 | 1.504 | 0.4513 | Yes | ||
35 | PRPS1 | 6350129 | 1749 | 1.447 | 0.4557 | Yes | ||
36 | UBXD1 | 5130079 5390167 | 1836 | 1.373 | 0.4580 | Yes | ||
37 | PLCG2 | 5720008 | 2048 | 1.183 | 0.4525 | No | ||
38 | MBNL1 | 2640762 7100048 | 2223 | 1.036 | 0.4483 | No | ||
39 | HSPD1 | 60097 2030451 | 2231 | 1.033 | 0.4531 | No | ||
40 | HIRA | 4480609 5270167 | 2257 | 1.025 | 0.4569 | No | ||
41 | RTN4 | 50725 630647 870097 870184 | 2392 | 0.973 | 0.4546 | No | ||
42 | ZCCHC7 | 6510592 | 2450 | 0.942 | 0.4562 | No | ||
43 | UBXD3 | 5050193 | 2554 | 0.873 | 0.4551 | No | ||
44 | ATP6V1A | 6590242 | 3053 | 0.596 | 0.4311 | No | ||
45 | RAB3IL1 | 380685 5420176 | 3220 | 0.517 | 0.4247 | No | ||
46 | MYST3 | 5270500 | 3239 | 0.510 | 0.4263 | No | ||
47 | CRY2 | 6290722 | 3290 | 0.491 | 0.4260 | No | ||
48 | UTX | 2900017 6770452 | 3292 | 0.490 | 0.4284 | No | ||
49 | PTMA | 5570148 | 3374 | 0.457 | 0.4264 | No | ||
50 | RBBP6 | 2320129 | 3493 | 0.418 | 0.4221 | No | ||
51 | RPL13A | 2680519 5700142 | 3504 | 0.415 | 0.4236 | No | ||
52 | SNX2 | 2470068 3360364 6510064 | 3659 | 0.364 | 0.4171 | No | ||
53 | LTBR | 2450341 | 3717 | 0.346 | 0.4158 | No | ||
54 | AMPD2 | 630093 1170070 | 3718 | 0.346 | 0.4175 | No | ||
55 | TCERG1 | 2350551 4540397 5220746 | 3721 | 0.345 | 0.4191 | No | ||
56 | SYT3 | 6380017 | 3732 | 0.342 | 0.4203 | No | ||
57 | GTF2H1 | 2570746 2650148 | 3831 | 0.315 | 0.4166 | No | ||
58 | CNNM1 | 2190433 | 3842 | 0.312 | 0.4176 | No | ||
59 | ATP6V0B | 2810112 | 3927 | 0.292 | 0.4145 | No | ||
60 | ALDH6A1 | 1770746 | 4033 | 0.270 | 0.4102 | No | ||
61 | SIRT1 | 1190731 | 4232 | 0.232 | 0.4006 | No | ||
62 | NR5A1 | 70707 | 4347 | 0.214 | 0.3955 | No | ||
63 | DSCAM | 1780050 2450731 2810438 | 4362 | 0.212 | 0.3958 | No | ||
64 | PPP1R3C | 2640170 | 4739 | 0.160 | 0.3763 | No | ||
65 | SNAP25 | 360520 | 4856 | 0.149 | 0.3707 | No | ||
66 | ETV1 | 70735 2940603 5080463 | 4979 | 0.138 | 0.3648 | No | ||
67 | SYNCRIP | 1690195 3140113 4670279 | 5008 | 0.136 | 0.3640 | No | ||
68 | ARRDC3 | 4610390 | 5168 | 0.122 | 0.3560 | No | ||
69 | NEUROG2 | 5420278 | 5280 | 0.114 | 0.3505 | No | ||
70 | HOXA1 | 1190524 5420142 | 5575 | 0.097 | 0.3351 | No | ||
71 | PICALM | 1940280 | 5577 | 0.097 | 0.3355 | No | ||
72 | NEUROD2 | 5290097 | 5821 | 0.086 | 0.3228 | No | ||
73 | JPH1 | 610739 | 6264 | 0.069 | 0.2991 | No | ||
74 | POGK | 5290315 | 6276 | 0.069 | 0.2989 | No | ||
75 | MRPL40 | 2370215 | 6304 | 0.068 | 0.2978 | No | ||
76 | TCEAL1 | 870577 | 6932 | 0.049 | 0.2640 | No | ||
77 | EIF3S10 | 1190079 3840176 | 6952 | 0.049 | 0.2632 | No | ||
78 | SYT6 | 2510280 3850128 4540064 | 6994 | 0.048 | 0.2612 | No | ||
79 | NKX2-2 | 4150731 | 7312 | 0.042 | 0.2443 | No | ||
80 | AKAP10 | 2630504 5910577 | 7313 | 0.042 | 0.2445 | No | ||
81 | DNMT3A | 4050068 4810717 | 7333 | 0.041 | 0.2437 | No | ||
82 | SLC38A5 | 540093 | 7809 | 0.032 | 0.2181 | No | ||
83 | XPO1 | 540707 | 7976 | 0.029 | 0.2092 | No | ||
84 | DNAJB9 | 460114 | 8175 | 0.025 | 0.1986 | No | ||
85 | ZBTB10 | 4200132 | 8183 | 0.025 | 0.1983 | No | ||
86 | FOXD3 | 6550156 | 8196 | 0.025 | 0.1978 | No | ||
87 | VLDLR | 870722 3060047 5340452 6550131 | 8322 | 0.023 | 0.1911 | No | ||
88 | PCDHA10 | 3830725 | 8382 | 0.022 | 0.1881 | No | ||
89 | NPTX1 | 3710736 | 8391 | 0.022 | 0.1877 | No | ||
90 | SNX5 | 1570021 6860609 | 8484 | 0.020 | 0.1828 | No | ||
91 | BMP2K | 60541 5570504 | 8689 | 0.017 | 0.1719 | No | ||
92 | HOXD10 | 6100039 | 8735 | 0.016 | 0.1695 | No | ||
93 | TBC1D15 | 870673 | 8853 | 0.014 | 0.1632 | No | ||
94 | ARMET | 5130670 | 9005 | 0.012 | 0.1551 | No | ||
95 | FOXF2 | 1240091 | 9091 | 0.011 | 0.1506 | No | ||
96 | TRPM7 | 2510408 | 9110 | 0.010 | 0.1496 | No | ||
97 | AP1S2 | 780279 4280707 | 9238 | 0.008 | 0.1428 | No | ||
98 | TBC1D5 | 5360619 6130603 | 9296 | 0.008 | 0.1397 | No | ||
99 | NPM1 | 4730427 | 9337 | 0.007 | 0.1376 | No | ||
100 | PHC3 | 4920332 | 9437 | 0.006 | 0.1323 | No | ||
101 | ODC1 | 5670168 | 9621 | 0.003 | 0.1224 | No | ||
102 | FLT3 | 2640487 | 9828 | -0.000 | 0.1112 | No | ||
103 | ABCA1 | 6290156 | 9882 | -0.001 | 0.1083 | No | ||
104 | HOXA11 | 6980133 | 9947 | -0.002 | 0.1049 | No | ||
105 | BHLHB3 | 3450438 | 10003 | -0.003 | 0.1019 | No | ||
106 | TIMM9 | 2450484 | 10266 | -0.007 | 0.0877 | No | ||
107 | ADAMTS19 | 2680739 | 10280 | -0.007 | 0.0871 | No | ||
108 | PAX6 | 1190025 | 10551 | -0.011 | 0.0725 | No | ||
109 | BMP4 | 380113 | 11090 | -0.020 | 0.0434 | No | ||
110 | NEUROD1 | 3060619 | 11111 | -0.021 | 0.0424 | No | ||
111 | TESK2 | 6520524 | 11382 | -0.026 | 0.0279 | No | ||
112 | SLCO1C1 | 5390494 | 11473 | -0.027 | 0.0232 | No | ||
113 | FGF14 | 2630390 3520075 6770048 | 11483 | -0.027 | 0.0228 | No | ||
114 | TGFB2 | 4920292 | 11759 | -0.033 | 0.0081 | No | ||
115 | BDNF | 2940128 3520368 | 11802 | -0.034 | 0.0060 | No | ||
116 | RCL1 | 1980408 2680008 3800176 | 11846 | -0.035 | 0.0038 | No | ||
117 | RNF128 | 1230300 5670273 | 12190 | -0.043 | -0.0146 | No | ||
118 | JAG1 | 3440390 | 12194 | -0.043 | -0.0145 | No | ||
119 | CELSR3 | 5270731 7100082 | 12409 | -0.048 | -0.0259 | No | ||
120 | HOXB5 | 2900538 | 12623 | -0.054 | -0.0372 | No | ||
121 | GATA5 | 430465 | 13147 | -0.071 | -0.0652 | No | ||
122 | GATA4 | 1410215 2690609 | 13425 | -0.083 | -0.0798 | No | ||
123 | CBX5 | 3830072 6290167 | 13495 | -0.086 | -0.0831 | No | ||
124 | TAC1 | 7000195 380706 | 13761 | -0.102 | -0.0969 | No | ||
125 | ELAVL3 | 2850014 | 13765 | -0.102 | -0.0966 | No | ||
126 | UBE2B | 4780497 | 13803 | -0.105 | -0.0980 | No | ||
127 | NRIP3 | 1340372 | 14161 | -0.134 | -0.1167 | No | ||
128 | ETV4 | 2450605 | 14172 | -0.135 | -0.1166 | No | ||
129 | SLC35A5 | 2970670 4480546 | 14207 | -0.138 | -0.1177 | No | ||
130 | DUSP7 | 2940309 | 14406 | -0.157 | -0.1277 | No | ||
131 | LAMP1 | 2470524 | 14522 | -0.170 | -0.1331 | No | ||
132 | MTUS1 | 780348 4920609 | 14828 | -0.223 | -0.1485 | No | ||
133 | HPS3 | 6650348 | 14884 | -0.234 | -0.1503 | No | ||
134 | ILF3 | 940722 3190647 6520110 | 15016 | -0.268 | -0.1560 | No | ||
135 | HOXB7 | 4540706 4610358 | 15205 | -0.323 | -0.1646 | No | ||
136 | ARF6 | 3520026 | 15246 | -0.339 | -0.1651 | No | ||
137 | CBARA1 | 360471 | 15271 | -0.349 | -0.1646 | No | ||
138 | DVL2 | 6110162 | 15325 | -0.365 | -0.1656 | No | ||
139 | EIF4E | 1580403 70133 6380215 | 15331 | -0.366 | -0.1641 | No | ||
140 | NDUFA7 | 5900722 | 15414 | -0.396 | -0.1665 | No | ||
141 | EGLN2 | 540086 | 15438 | -0.407 | -0.1657 | No | ||
142 | MTCH2 | 3780603 6620215 | 15458 | -0.418 | -0.1646 | No | ||
143 | IL15RA | 2570270 3190711 6100091 6100270 | 15505 | -0.435 | -0.1649 | No | ||
144 | DCTN4 | 3390010 5550170 | 15512 | -0.437 | -0.1630 | No | ||
145 | PAK2 | 360438 7050068 | 15518 | -0.438 | -0.1611 | No | ||
146 | B3GALT6 | 50195 | 15535 | -0.447 | -0.1597 | No | ||
147 | STX6 | 4850750 6770278 | 15661 | -0.501 | -0.1640 | No | ||
148 | MNT | 4920575 | 15674 | -0.510 | -0.1621 | No | ||
149 | ARMCX3 | 3290309 | 15827 | -0.580 | -0.1674 | No | ||
150 | PDGFB | 3060440 6370008 | 15889 | -0.613 | -0.1676 | No | ||
151 | SMYD4 | 2640403 | 16128 | -0.751 | -0.1767 | No | ||
152 | CSRP2BP | 4570717 5550333 | 16197 | -0.791 | -0.1764 | No | ||
153 | PABPN1 | 460519 | 16210 | -0.806 | -0.1730 | No | ||
154 | SCYL1 | 5050717 | 16346 | -0.908 | -0.1757 | No | ||
155 | UBE1 | 4150139 7050463 | 16518 | -1.011 | -0.1799 | No | ||
156 | RPA1 | 360452 | 16553 | -1.031 | -0.1766 | No | ||
157 | EPC1 | 1570050 5290095 6900193 | 16571 | -1.040 | -0.1722 | No | ||
158 | CHD4 | 5420059 6130338 6380717 | 16744 | -1.194 | -0.1755 | No | ||
159 | ESRRA | 6550242 | 16823 | -1.271 | -0.1734 | No | ||
160 | COMMD8 | 5890358 | 16835 | -1.285 | -0.1675 | No | ||
161 | ATF7IP | 2690176 6770021 | 16981 | -1.427 | -0.1681 | No | ||
162 | TEF | 1050050 3120397 4060487 | 17205 | -1.711 | -0.1716 | No | ||
163 | MAP2K6 | 1230056 2940204 | 17557 | -2.234 | -0.1794 | No | ||
164 | LEF1 | 2470082 7100288 | 17571 | -2.264 | -0.1687 | No | ||
165 | LZTS2 | 2260440 | 17810 | -2.702 | -0.1680 | No | ||
166 | AP1GBP1 | 2510372 | 17816 | -2.729 | -0.1545 | No | ||
167 | KBTBD2 | 2320014 | 17988 | -3.150 | -0.1479 | No | ||
168 | HOXA7 | 5910152 | 18035 | -3.305 | -0.1337 | No | ||
169 | FXYD6 | 3870164 | 18111 | -3.565 | -0.1198 | No | ||
170 | BRD2 | 1450300 5340484 6100605 | 18221 | -3.988 | -0.1056 | No | ||
171 | NIT1 | 1230338 3940671 | 18256 | -4.174 | -0.0864 | No | ||
172 | BCL11B | 2680673 | 18265 | -4.208 | -0.0656 | No | ||
173 | RNF44 | 5910692 | 18353 | -4.723 | -0.0465 | No | ||
174 | ZFYVE26 | 6860152 | 18368 | -4.851 | -0.0228 | No | ||
175 | ISGF3G | 3190131 7100142 | 18568 | -7.181 | 0.0026 | No |