Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D |
Enrichment Score (ES) | -0.5472736 |
Normalized Enrichment Score (NES) | -1.5507209 |
Nominal p-value | 0.0 |
FDR q-value | 0.12649357 |
FWER p-Value | 0.571 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SLC6A9 | 2470520 | 108 | 5.216 | 0.0179 | No | ||
2 | SDC1 | 3440471 6350408 | 533 | 3.182 | 0.0094 | No | ||
3 | RBBP7 | 430113 450450 2370309 | 566 | 3.123 | 0.0220 | No | ||
4 | APP | 2510053 | 634 | 2.946 | 0.0318 | No | ||
5 | TNFAIP1 | 6940593 | 772 | 2.674 | 0.0365 | No | ||
6 | LEFTY1 | 3290452 | 806 | 2.605 | 0.0466 | No | ||
7 | RPS6KA1 | 4120647 | 928 | 2.406 | 0.0510 | No | ||
8 | INHBB | 2680092 | 1032 | 2.255 | 0.0557 | No | ||
9 | RGMA | 2450711 | 1041 | 2.249 | 0.0656 | No | ||
10 | AK2 | 4590458 4760195 6110097 | 1395 | 1.814 | 0.0547 | No | ||
11 | CXXC6 | 2810168 | 1398 | 1.803 | 0.0628 | No | ||
12 | PPP3R1 | 1190041 1570487 | 1592 | 1.581 | 0.0595 | No | ||
13 | CUGBP2 | 6180121 6840139 | 1638 | 1.548 | 0.0641 | No | ||
14 | MRPS25 | 610441 870128 1410368 | 1669 | 1.529 | 0.0695 | No | ||
15 | DAZAP2 | 6200102 | 1673 | 1.526 | 0.0763 | No | ||
16 | RPS6KA3 | 1980707 | 1801 | 1.399 | 0.0758 | No | ||
17 | NEK9 | 3440402 | 2058 | 1.175 | 0.0672 | No | ||
18 | SENP1 | 6100537 | 2076 | 1.161 | 0.0716 | No | ||
19 | TRPS1 | 870100 | 2081 | 1.158 | 0.0767 | No | ||
20 | YWHAZ | 1230717 | 2170 | 1.080 | 0.0768 | No | ||
21 | CDCA7 | 3060097 | 2203 | 1.051 | 0.0799 | No | ||
22 | RAB22A | 110500 3830707 | 2444 | 0.943 | 0.0712 | No | ||
23 | TRIM36 | 1400600 1980082 5130037 | 2466 | 0.930 | 0.0743 | No | ||
24 | CCND1 | 460524 770309 3120576 6980398 | 2475 | 0.923 | 0.0780 | No | ||
25 | YTHDF3 | 4540632 4670717 7040609 | 2786 | 0.728 | 0.0645 | No | ||
26 | MARCH8 | 60397 | 2798 | 0.719 | 0.0672 | No | ||
27 | NEO1 | 1990154 | 2816 | 0.713 | 0.0695 | No | ||
28 | ASF1A | 7050020 | 2826 | 0.710 | 0.0723 | No | ||
29 | PBX3 | 1300424 3710577 6180575 | 2884 | 0.679 | 0.0723 | No | ||
30 | RBL1 | 3130372 | 2963 | 0.637 | 0.0710 | No | ||
31 | NR4A2 | 60273 | 3183 | 0.532 | 0.0615 | No | ||
32 | ADAM9 | 3360411 | 3222 | 0.517 | 0.0618 | No | ||
33 | ZFP36L2 | 510180 | 3253 | 0.506 | 0.0625 | No | ||
34 | SS18L1 | 4610180 6550068 | 3307 | 0.483 | 0.0618 | No | ||
35 | PFN2 | 730040 5700026 | 3390 | 0.451 | 0.0594 | No | ||
36 | RDBP | 6590044 | 3464 | 0.429 | 0.0574 | No | ||
37 | DCUN1D1 | 2360332 | 3648 | 0.369 | 0.0491 | No | ||
38 | ARID4B | 730754 6660026 | 3702 | 0.351 | 0.0478 | No | ||
39 | ANKRD13C | 5270202 | 4043 | 0.267 | 0.0306 | No | ||
40 | SAR1B | 2510273 | 4064 | 0.262 | 0.0307 | No | ||
41 | RHOC | 2060242 | 4073 | 0.260 | 0.0314 | No | ||
42 | KPNA2 | 3450114 | 4093 | 0.257 | 0.0316 | No | ||
43 | MBNL2 | 3450707 | 4249 | 0.230 | 0.0242 | No | ||
44 | POLQ | 1050053 2190102 | 4296 | 0.223 | 0.0227 | No | ||
45 | EDNRB | 4280717 6400435 | 4381 | 0.207 | 0.0191 | No | ||
46 | PCDHA11 | 1510253 | 4445 | 0.199 | 0.0166 | No | ||
47 | ST8SIA2 | 2680082 | 4509 | 0.190 | 0.0140 | No | ||
48 | ESR1 | 4060372 5860193 | 4607 | 0.176 | 0.0095 | No | ||
49 | NFIB | 460450 | 4641 | 0.173 | 0.0085 | No | ||
50 | DPYSL5 | 4900333 | 4786 | 0.155 | 0.0014 | No | ||
51 | RABGAP1 | 5050397 | 4830 | 0.151 | -0.0002 | No | ||
52 | BRMS1L | 6110609 | 4933 | 0.142 | -0.0051 | No | ||
53 | ETV1 | 70735 2940603 5080463 | 4979 | 0.138 | -0.0070 | No | ||
54 | LASS6 | 5890576 6520138 | 5007 | 0.136 | -0.0078 | No | ||
55 | PCDHA6 | 780333 2370280 | 5203 | 0.120 | -0.0179 | No | ||
56 | RNF6 | 2640035 | 5257 | 0.116 | -0.0202 | No | ||
57 | DRD1 | 430025 | 5530 | 0.100 | -0.0345 | No | ||
58 | PURB | 5360138 | 5595 | 0.097 | -0.0376 | No | ||
59 | RABEP1 | 4760427 6200463 | 5691 | 0.091 | -0.0423 | No | ||
60 | ARHGEF10 | 3120593 6900673 | 5696 | 0.091 | -0.0421 | No | ||
61 | LATS2 | 4480593 6020494 | 5705 | 0.091 | -0.0422 | No | ||
62 | RALGDS | 430463 | 5823 | 0.085 | -0.0481 | No | ||
63 | UBE2J1 | 4070133 | 5865 | 0.084 | -0.0500 | No | ||
64 | FNDC3A | 2690097 3290044 | 5920 | 0.082 | -0.0525 | No | ||
65 | ZFPM2 | 460072 | 5936 | 0.081 | -0.0530 | No | ||
66 | OLFM3 | 580112 1050072 4070204 | 6009 | 0.078 | -0.0565 | No | ||
67 | MLLT6 | 3870168 | 6273 | 0.069 | -0.0705 | No | ||
68 | SYNC1 | 580114 | 6501 | 0.062 | -0.0826 | No | ||
69 | FLT1 | 3830167 4920438 | 6508 | 0.062 | -0.0826 | No | ||
70 | PHF6 | 3120632 3990041 | 6828 | 0.052 | -0.0997 | No | ||
71 | NPAS3 | 630408 4610066 | 6832 | 0.052 | -0.0996 | No | ||
72 | TIPARP | 50397 | 6918 | 0.050 | -0.1040 | No | ||
73 | UBE2R2 | 1230504 | 6948 | 0.049 | -0.1054 | No | ||
74 | ZBTB4 | 6450441 | 6970 | 0.048 | -0.1063 | No | ||
75 | ECT2 | 3830086 | 6972 | 0.048 | -0.1061 | No | ||
76 | MEF2C | 670025 780338 | 7167 | 0.044 | -0.1165 | No | ||
77 | OXR1 | 2370039 3190706 | 7412 | 0.040 | -0.1296 | No | ||
78 | RSBN1 | 7000487 | 7541 | 0.037 | -0.1364 | No | ||
79 | PLXNA1 | 70066 | 7594 | 0.036 | -0.1390 | No | ||
80 | WEE1 | 3390070 | 7693 | 0.034 | -0.1442 | No | ||
81 | ZKSCAN1 | 6380605 | 7811 | 0.032 | -0.1504 | No | ||
82 | OSBPL8 | 50603 | 7816 | 0.032 | -0.1505 | No | ||
83 | KCNMA1 | 1450402 | 7895 | 0.030 | -0.1546 | No | ||
84 | FOXL2 | 5670537 | 7941 | 0.029 | -0.1569 | No | ||
85 | LHX8 | 5700347 | 8121 | 0.026 | -0.1665 | No | ||
86 | TAOK2 | 110575 6380692 | 8255 | 0.024 | -0.1736 | No | ||
87 | PCDHA12 | 2810215 | 8261 | 0.024 | -0.1738 | No | ||
88 | VLDLR | 870722 3060047 5340452 6550131 | 8322 | 0.023 | -0.1770 | No | ||
89 | VSX1 | 4610605 6650112 | 8323 | 0.023 | -0.1769 | No | ||
90 | PCDHA10 | 3830725 | 8382 | 0.022 | -0.1799 | No | ||
91 | KLF12 | 1660095 4810288 5340546 6520286 | 8472 | 0.021 | -0.1847 | No | ||
92 | SLC2A4 | 540441 | 8543 | 0.020 | -0.1884 | No | ||
93 | SSX2IP | 4610176 | 8554 | 0.019 | -0.1888 | No | ||
94 | TLOC1 | 4050309 | 8823 | 0.015 | -0.2033 | No | ||
95 | PCDHA1 | 940026 540484 | 8962 | 0.013 | -0.2108 | No | ||
96 | TMEM16F | 5860008 | 8997 | 0.012 | -0.2126 | No | ||
97 | PRDM8 | 840746 | 9002 | 0.012 | -0.2127 | No | ||
98 | PCDHA3 | 3840402 | 9046 | 0.011 | -0.2150 | No | ||
99 | BRP44L | 1340605 | 9196 | 0.009 | -0.2231 | No | ||
100 | MMP24 | 5340154 | 9203 | 0.009 | -0.2234 | No | ||
101 | ANK2 | 6510546 | 9438 | 0.006 | -0.2361 | No | ||
102 | EPAS1 | 5290156 | 9553 | 0.004 | -0.2422 | No | ||
103 | ALX4 | 3870019 | 9569 | 0.004 | -0.2430 | No | ||
104 | ZBTB11 | 6520092 | 9578 | 0.004 | -0.2435 | No | ||
105 | BAMBI | 6650463 | 9589 | 0.004 | -0.2440 | No | ||
106 | OSBPL5 | 3840537 6040286 | 9654 | 0.002 | -0.2475 | No | ||
107 | PURA | 3870156 | 9881 | -0.001 | -0.2597 | No | ||
108 | ABCA1 | 6290156 | 9882 | -0.001 | -0.2597 | No | ||
109 | RAD23B | 2190671 | 10154 | -0.006 | -0.2744 | No | ||
110 | ZMYND11 | 630181 2570019 4850138 5360040 | 10252 | -0.007 | -0.2797 | No | ||
111 | GABPB2 | 6130450 7050735 | 10310 | -0.008 | -0.2827 | No | ||
112 | PCAF | 2230161 2570369 6550451 | 10438 | -0.010 | -0.2896 | No | ||
113 | PCDHA5 | 2970347 | 10718 | -0.014 | -0.3047 | No | ||
114 | PAK7 | 3830164 | 10835 | -0.016 | -0.3109 | No | ||
115 | NEUROD1 | 3060619 | 11111 | -0.021 | -0.3258 | No | ||
116 | MYT1L | 5670369 6660403 | 11308 | -0.024 | -0.3363 | No | ||
117 | ATAD2 | 870242 2260687 | 11471 | -0.027 | -0.3450 | No | ||
118 | NTN4 | 6940398 | 11492 | -0.028 | -0.3460 | No | ||
119 | HLF | 2370113 | 11500 | -0.028 | -0.3462 | No | ||
120 | CCNJ | 870047 | 11755 | -0.033 | -0.3599 | No | ||
121 | ATP2B2 | 3780397 | 12068 | -0.040 | -0.3767 | No | ||
122 | TRPV6 | 4010717 | 12075 | -0.040 | -0.3768 | No | ||
123 | PCDHA7 | 1850019 | 12301 | -0.045 | -0.3888 | No | ||
124 | LHX6 | 2360731 3360397 | 12341 | -0.046 | -0.3908 | No | ||
125 | E2F5 | 5860575 | 12468 | -0.049 | -0.3974 | No | ||
126 | NEUROD6 | 4670731 | 12470 | -0.049 | -0.3972 | No | ||
127 | CREB5 | 2320368 | 12691 | -0.056 | -0.4089 | No | ||
128 | PGBD5 | 1190047 | 12848 | -0.061 | -0.4171 | No | ||
129 | LUC7L2 | 1850402 6350088 | 12865 | -0.061 | -0.4177 | No | ||
130 | PAPOLA | 4200286 4850112 | 12868 | -0.061 | -0.4175 | No | ||
131 | SLITRK3 | 5910041 | 12929 | -0.063 | -0.4205 | No | ||
132 | PARP8 | 4150204 | 12987 | -0.065 | -0.4233 | No | ||
133 | NR4A3 | 2900021 5860095 5910039 | 13009 | -0.066 | -0.4242 | No | ||
134 | DHX40 | 360672 | 13186 | -0.073 | -0.4334 | No | ||
135 | PLEKHA3 | 5080068 | 13456 | -0.084 | -0.4476 | No | ||
136 | RB1CC1 | 510494 7100072 | 13468 | -0.084 | -0.4478 | No | ||
137 | PRRX1 | 4120193 4480390 | 13550 | -0.090 | -0.4518 | No | ||
138 | DDHD1 | 3450241 3940523 6380156 | 13641 | -0.096 | -0.4563 | No | ||
139 | CYP26B1 | 2630142 | 13657 | -0.096 | -0.4567 | No | ||
140 | UBE2B | 4780497 | 13803 | -0.105 | -0.4641 | No | ||
141 | GNB5 | 4480736 6550722 6770463 | 13969 | -0.118 | -0.4725 | No | ||
142 | TARDBP | 870390 2350093 | 13980 | -0.119 | -0.4725 | No | ||
143 | KLHL18 | 4560075 | 14072 | -0.126 | -0.4769 | No | ||
144 | ARID4A | 520156 1050707 | 14193 | -0.137 | -0.4828 | No | ||
145 | RGL1 | 1500097 6900450 | 14239 | -0.141 | -0.4846 | No | ||
146 | RAB11FIP1 | 2470333 | 14246 | -0.142 | -0.4842 | No | ||
147 | FGD5 | 3520438 4060500 | 14364 | -0.152 | -0.4899 | No | ||
148 | MKNK2 | 1240020 5270092 | 14407 | -0.157 | -0.4915 | No | ||
149 | MUTED | 3140452 4610086 4730348 | 14500 | -0.167 | -0.4957 | No | ||
150 | NR2C2 | 6100097 | 14699 | -0.197 | -0.5056 | No | ||
151 | ARHGEF17 | 2060008 | 14748 | -0.207 | -0.5072 | No | ||
152 | CFL2 | 380239 6200368 | 14820 | -0.221 | -0.5101 | No | ||
153 | MTUS1 | 780348 4920609 | 14828 | -0.223 | -0.5095 | No | ||
154 | PLAG1 | 1450142 3870139 6520039 | 14906 | -0.239 | -0.5125 | No | ||
155 | MINK1 | 5860647 | 14908 | -0.240 | -0.5115 | No | ||
156 | EPHA2 | 5890056 | 15022 | -0.269 | -0.5164 | No | ||
157 | CRIM1 | 130491 | 15030 | -0.272 | -0.5156 | No | ||
158 | YPEL2 | 5560609 | 15157 | -0.308 | -0.5210 | No | ||
159 | BCL2L11 | 780044 4200601 | 15249 | -0.339 | -0.5244 | No | ||
160 | SNF1LK | 6110403 | 15311 | -0.360 | -0.5261 | No | ||
161 | ZNF385 | 450176 4810358 | 15490 | -0.429 | -0.5338 | No | ||
162 | SUV39H1 | 630112 | 15542 | -0.450 | -0.5345 | No | ||
163 | SPOP | 450035 | 15589 | -0.469 | -0.5349 | No | ||
164 | TAL1 | 7040239 | 15617 | -0.479 | -0.5341 | No | ||
165 | MNT | 4920575 | 15674 | -0.510 | -0.5349 | No | ||
166 | RAB6A | 3840463 4780731 | 15740 | -0.541 | -0.5359 | No | ||
167 | E2F7 | 4200056 | 15794 | -0.566 | -0.5362 | No | ||
168 | DMTF1 | 5910047 1570497 2480100 6620239 | 15871 | -0.603 | -0.5376 | No | ||
169 | RPS6KA5 | 2120563 7040546 | 15915 | -0.625 | -0.5371 | No | ||
170 | HN1 | 3360156 | 15969 | -0.656 | -0.5370 | No | ||
171 | ORMDL3 | 1340711 | 16042 | -0.692 | -0.5377 | No | ||
172 | COL23A1 | 2030358 | 16136 | -0.754 | -0.5393 | No | ||
173 | FRMD4A | 2190176 | 16156 | -0.764 | -0.5369 | No | ||
174 | PLEKHM1 | 1050161 1990750 | 16162 | -0.768 | -0.5336 | No | ||
175 | DNAJA2 | 2630253 6860358 | 16312 | -0.885 | -0.5377 | No | ||
176 | MAPK9 | 2060273 3780209 4070397 | 16489 | -0.997 | -0.5427 | Yes | ||
177 | MTMR3 | 1050014 4920180 | 16517 | -1.011 | -0.5396 | Yes | ||
178 | ATXN1 | 5550156 | 16523 | -1.014 | -0.5352 | Yes | ||
179 | RAB11A | 5360079 | 16598 | -1.060 | -0.5344 | Yes | ||
180 | CRK | 1230162 4780128 | 16625 | -1.085 | -0.5309 | Yes | ||
181 | SMAD2 | 4200592 | 16628 | -1.088 | -0.5260 | Yes | ||
182 | AEBP2 | 2970603 | 16756 | -1.208 | -0.5274 | Yes | ||
183 | IQWD1 | 160475 | 16802 | -1.259 | -0.5241 | Yes | ||
184 | FEM1C | 60300 6130717 6980164 | 16822 | -1.271 | -0.5193 | Yes | ||
185 | NFYA | 5860368 | 17037 | -1.493 | -0.5241 | Yes | ||
186 | PERQ1 | 1340164 | 17072 | -1.539 | -0.5189 | Yes | ||
187 | HRBL | 1850102 3830253 4780176 | 17247 | -1.764 | -0.5203 | Yes | ||
188 | RASSF2 | 2480079 5720546 | 17254 | -1.776 | -0.5126 | Yes | ||
189 | WDR37 | 2630519 6840347 | 17294 | -1.817 | -0.5064 | Yes | ||
190 | MECP2 | 1940450 | 17335 | -1.863 | -0.5001 | Yes | ||
191 | BCL11A | 6860369 | 17349 | -1.884 | -0.4922 | Yes | ||
192 | TUSC2 | 1580253 | 17371 | -1.914 | -0.4846 | Yes | ||
193 | CCND2 | 5340167 | 17384 | -1.954 | -0.4763 | Yes | ||
194 | MAP3K14 | 5890435 | 17399 | -1.981 | -0.4680 | Yes | ||
195 | HIC2 | 4010433 | 17404 | -1.988 | -0.4591 | Yes | ||
196 | SF4 | 3830341 | 17463 | -2.080 | -0.4528 | Yes | ||
197 | RUNX1 | 3840711 | 17468 | -2.087 | -0.4435 | Yes | ||
198 | LEF1 | 2470082 7100288 | 17571 | -2.264 | -0.4387 | Yes | ||
199 | DUSP2 | 2370184 | 17680 | -2.450 | -0.4334 | Yes | ||
200 | MKRN1 | 1410097 | 17729 | -2.546 | -0.4244 | Yes | ||
201 | ZDHHC9 | 3940204 | 17815 | -2.728 | -0.4165 | Yes | ||
202 | PPP6C | 2450670 | 17827 | -2.761 | -0.4045 | Yes | ||
203 | ASF1B | 6590706 | 17837 | -2.780 | -0.3923 | Yes | ||
204 | FOXJ2 | 2450441 | 17877 | -2.870 | -0.3813 | Yes | ||
205 | MAP3K11 | 7000039 | 17924 | -2.956 | -0.3703 | Yes | ||
206 | RRAGD | 670075 | 17970 | -3.093 | -0.3586 | Yes | ||
207 | ULK1 | 6100315 | 18024 | -3.270 | -0.3466 | Yes | ||
208 | CREBL1 | 1340546 | 18046 | -3.325 | -0.3325 | Yes | ||
209 | TLE4 | 1450064 1500519 | 18118 | -3.582 | -0.3200 | Yes | ||
210 | IRF2 | 5390044 | 18270 | -4.237 | -0.3089 | Yes | ||
211 | MCL1 | 1660672 | 18272 | -4.239 | -0.2896 | Yes | ||
212 | WDR45 | 1660538 | 18273 | -4.240 | -0.2702 | Yes | ||
213 | TOB2 | 1240465 | 18313 | -4.507 | -0.2518 | Yes | ||
214 | ZFYVE26 | 6860152 | 18368 | -4.851 | -0.2326 | Yes | ||
215 | BCL6 | 940100 | 18378 | -4.903 | -0.2106 | Yes | ||
216 | IHPK1 | 1340053 | 18405 | -5.119 | -0.1887 | Yes | ||
217 | TOX | 3440053 | 18421 | -5.218 | -0.1657 | Yes | ||
218 | KLF13 | 4670563 | 18431 | -5.352 | -0.1417 | Yes | ||
219 | MAML1 | 2760008 | 18432 | -5.364 | -0.1172 | Yes | ||
220 | PLAGL2 | 1770148 | 18480 | -5.805 | -0.0933 | Yes | ||
221 | ARHGEF18 | 2120279 | 18501 | -6.079 | -0.0666 | Yes | ||
222 | PHF2 | 4060300 | 18547 | -6.671 | -0.0386 | Yes | ||
223 | BTG1 | 4200735 6040131 6200133 | 18611 | -9.256 | 0.0003 | Yes |