Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | PENG_GLUTAMINE_DN |
Enrichment Score (ES) | 0.58916485 |
Normalized Enrichment Score (NES) | 1.6756198 |
Nominal p-value | 0.0 |
FDR q-value | 0.040805805 |
FWER p-Value | 0.453 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | BOP1 | 4810040 | 34 | 6.852 | 0.0152 | Yes | ||
2 | FBL | 5130020 | 37 | 6.713 | 0.0318 | Yes | ||
3 | VARS2 | 1410017 3800114 4210270 | 38 | 6.639 | 0.0483 | Yes | ||
4 | RUVBL2 | 1190377 | 63 | 5.901 | 0.0616 | Yes | ||
5 | IFRD2 | 4150110 | 77 | 5.595 | 0.0749 | Yes | ||
6 | C1QBP | 3170452 | 88 | 5.442 | 0.0878 | Yes | ||
7 | CCT6A | 2350368 | 104 | 5.267 | 0.1001 | Yes | ||
8 | NOLC1 | 2350195 | 110 | 5.205 | 0.1128 | Yes | ||
9 | EIF2B5 | 430315 6900400 | 121 | 5.137 | 0.1250 | Yes | ||
10 | TBL3 | 6020575 | 123 | 5.101 | 0.1377 | Yes | ||
11 | SLC29A1 | 2970379 | 131 | 5.040 | 0.1498 | Yes | ||
12 | CYC1 | 2850546 | 154 | 4.832 | 0.1606 | Yes | ||
13 | DDX18 | 6980619 | 155 | 4.811 | 0.1726 | Yes | ||
14 | FASN | 430717 | 160 | 4.787 | 0.1843 | Yes | ||
15 | FUS | 4760619 | 201 | 4.505 | 0.1933 | Yes | ||
16 | MRPL12 | 3120112 | 204 | 4.467 | 0.2043 | Yes | ||
17 | TFRC | 4050551 | 213 | 4.421 | 0.2149 | Yes | ||
18 | CAD | 2340717 | 214 | 4.419 | 0.2258 | Yes | ||
19 | PA2G4 | 2030463 | 218 | 4.396 | 0.2366 | Yes | ||
20 | NUDC | 4780025 | 234 | 4.307 | 0.2465 | Yes | ||
21 | MRPL3 | 1170736 5270025 | 290 | 4.043 | 0.2536 | Yes | ||
22 | DDX21 | 6100446 | 298 | 3.996 | 0.2631 | Yes | ||
23 | NOL5A | 5570139 | 312 | 3.941 | 0.2722 | Yes | ||
24 | LDHA | 2190594 | 314 | 3.939 | 0.2820 | Yes | ||
25 | ALDOA | 6290672 | 348 | 3.761 | 0.2895 | Yes | ||
26 | PRDX4 | 3800039 | 350 | 3.754 | 0.2988 | Yes | ||
27 | DDX1 | 3450047 | 366 | 3.693 | 0.3072 | Yes | ||
28 | SNRP70 | 4200181 | 376 | 3.661 | 0.3158 | Yes | ||
29 | NOL1 | 4570576 4920044 | 405 | 3.564 | 0.3231 | Yes | ||
30 | ABCF1 | 2630707 2760273 3520725 | 416 | 3.537 | 0.3314 | Yes | ||
31 | FKBP4 | 870035 | 434 | 3.492 | 0.3391 | Yes | ||
32 | TCEB1 | 1170619 | 447 | 3.431 | 0.3470 | Yes | ||
33 | RNF126 | 2650672 4560563 | 452 | 3.419 | 0.3553 | Yes | ||
34 | MRPL28 | 3520673 | 454 | 3.418 | 0.3637 | Yes | ||
35 | NME1 | 770014 | 457 | 3.394 | 0.3721 | Yes | ||
36 | SLC19A1 | 6770139 | 463 | 3.372 | 0.3802 | Yes | ||
37 | SYNGR2 | 4050332 4560091 6130348 | 472 | 3.329 | 0.3880 | Yes | ||
38 | SCD | 2680441 | 508 | 3.238 | 0.3942 | Yes | ||
39 | TIMM17A | 130092 | 530 | 3.187 | 0.4009 | Yes | ||
40 | SLC5A6 | 2570438 | 561 | 3.128 | 0.4071 | Yes | ||
41 | HSPE1 | 3170438 | 569 | 3.119 | 0.4145 | Yes | ||
42 | PAICS | 610142 | 608 | 3.017 | 0.4199 | Yes | ||
43 | MAPRE2 | 1660435 5860403 | 620 | 2.981 | 0.4267 | Yes | ||
44 | IDH3A | 460332 | 630 | 2.963 | 0.4336 | Yes | ||
45 | PSMD8 | 630142 | 645 | 2.912 | 0.4401 | Yes | ||
46 | UBE2M | 2450215 | 696 | 2.835 | 0.4444 | Yes | ||
47 | SRM | 1850097 2480162 | 698 | 2.834 | 0.4514 | Yes | ||
48 | SNRPF | 3170280 | 754 | 2.717 | 0.4552 | Yes | ||
49 | PIK3R3 | 1770333 | 789 | 2.640 | 0.4599 | Yes | ||
50 | PIK3R2 | 1660193 | 807 | 2.604 | 0.4654 | Yes | ||
51 | PRDX1 | 5720253 | 814 | 2.586 | 0.4715 | Yes | ||
52 | NMT1 | 5810152 | 836 | 2.551 | 0.4767 | Yes | ||
53 | CTPS | 70451 1740132 | 844 | 2.532 | 0.4826 | Yes | ||
54 | CSE1L | 3850086 | 848 | 2.524 | 0.4887 | Yes | ||
55 | PSMD3 | 1400647 | 849 | 2.522 | 0.4950 | Yes | ||
56 | LMNB1 | 5890292 6020008 | 851 | 2.519 | 0.5012 | Yes | ||
57 | MRPS12 | 4210707 6110341 | 863 | 2.507 | 0.5069 | Yes | ||
58 | PES1 | 2470427 | 878 | 2.487 | 0.5123 | Yes | ||
59 | NCL | 2360463 4540279 | 893 | 2.461 | 0.5176 | Yes | ||
60 | ALG3 | 2650647 7100131 | 905 | 2.442 | 0.5231 | Yes | ||
61 | CCT5 | 1050670 | 965 | 2.341 | 0.5257 | Yes | ||
62 | IFI30 | 730309 2940500 | 996 | 2.308 | 0.5298 | Yes | ||
63 | CYCS | 2030072 | 1055 | 2.235 | 0.5322 | Yes | ||
64 | KARS | 6520575 | 1141 | 2.134 | 0.5329 | Yes | ||
65 | PSMB3 | 4280594 | 1152 | 2.119 | 0.5377 | Yes | ||
66 | PSMD12 | 730044 | 1154 | 2.117 | 0.5429 | Yes | ||
67 | UMPS | 2340541 4730438 | 1214 | 2.044 | 0.5447 | Yes | ||
68 | GMPS | 460670 | 1227 | 2.028 | 0.5491 | Yes | ||
69 | PSMB6 | 2690711 | 1234 | 2.020 | 0.5538 | Yes | ||
70 | TOMM40 | 6110017 | 1256 | 1.984 | 0.5576 | Yes | ||
71 | COPS3 | 780039 | 1291 | 1.952 | 0.5606 | Yes | ||
72 | BZW1 | 460270 | 1305 | 1.935 | 0.5647 | Yes | ||
73 | AK2 | 4590458 4760195 6110097 | 1395 | 1.814 | 0.5644 | Yes | ||
74 | IMPDH1 | 3190735 7050546 | 1418 | 1.779 | 0.5676 | Yes | ||
75 | HPRT1 | 1690398 4920619 6350170 | 1589 | 1.584 | 0.5623 | Yes | ||
76 | EIF4G1 | 4070446 | 1608 | 1.575 | 0.5653 | Yes | ||
77 | CCT2 | 1690113 | 1716 | 1.480 | 0.5631 | Yes | ||
78 | PRPS1 | 6350129 | 1749 | 1.447 | 0.5650 | Yes | ||
79 | CDC25A | 3800184 | 1784 | 1.416 | 0.5666 | Yes | ||
80 | TCP1 | 2450100 5130524 | 1856 | 1.357 | 0.5662 | Yes | ||
81 | ATR | 6860273 | 1897 | 1.312 | 0.5672 | Yes | ||
82 | GSPT1 | 5420050 | 1973 | 1.241 | 0.5663 | Yes | ||
83 | PDCD4 | 3360403 5690110 | 2001 | 1.213 | 0.5678 | Yes | ||
84 | NUP160 | 1990551 | 2080 | 1.158 | 0.5664 | Yes | ||
85 | ATP2A2 | 1090075 3990279 | 2127 | 1.117 | 0.5667 | Yes | ||
86 | CELSR2 | 2320148 6220152 | 2160 | 1.089 | 0.5677 | Yes | ||
87 | TGFB1 | 1940162 | 2180 | 1.073 | 0.5693 | Yes | ||
88 | MORF4L2 | 6450133 | 2235 | 1.032 | 0.5689 | Yes | ||
89 | VDAC1 | 4760059 | 2241 | 1.029 | 0.5712 | Yes | ||
90 | SFRS2 | 50707 380593 | 2242 | 1.028 | 0.5738 | Yes | ||
91 | EMP3 | 1500722 1570039 | 2248 | 1.027 | 0.5761 | Yes | ||
92 | PSMF1 | 5340056 | 2249 | 1.027 | 0.5786 | Yes | ||
93 | SMARCC1 | 5080019 7100047 | 2256 | 1.025 | 0.5808 | Yes | ||
94 | TRIP13 | 6860341 | 2261 | 1.023 | 0.5832 | Yes | ||
95 | PGAM1 | 2570133 | 2265 | 1.021 | 0.5855 | Yes | ||
96 | CTSC | 2230739 4670408 | 2340 | 0.998 | 0.5840 | Yes | ||
97 | AHSA1 | 2030520 | 2391 | 0.974 | 0.5837 | Yes | ||
98 | BTK | 3130044 | 2440 | 0.945 | 0.5834 | Yes | ||
99 | EIF5 | 6380750 | 2465 | 0.931 | 0.5845 | Yes | ||
100 | CCND1 | 460524 770309 3120576 6980398 | 2475 | 0.923 | 0.5863 | Yes | ||
101 | RQCD1 | 1850139 | 2479 | 0.916 | 0.5884 | Yes | ||
102 | NUP98 | 2850465 | 2553 | 0.874 | 0.5866 | Yes | ||
103 | FKBP2 | 2320025 | 2618 | 0.830 | 0.5852 | Yes | ||
104 | DHX15 | 870632 | 2645 | 0.814 | 0.5858 | Yes | ||
105 | RPLP2 | 5290020 | 2653 | 0.809 | 0.5874 | Yes | ||
106 | DHCR24 | 840600 1050672 6290097 | 2673 | 0.795 | 0.5883 | Yes | ||
107 | HSPA5 | 5130671 | 2708 | 0.771 | 0.5884 | Yes | ||
108 | MLF2 | 1940176 | 2730 | 0.761 | 0.5892 | Yes | ||
109 | EEF1E1 | 4540711 | 2850 | 0.695 | 0.5844 | No | ||
110 | PSME4 | 380348 1770131 | 2863 | 0.687 | 0.5855 | No | ||
111 | LAMB3 | 7100301 | 2890 | 0.676 | 0.5857 | No | ||
112 | TUBG1 | 3140204 | 2999 | 0.621 | 0.5814 | No | ||
113 | SF3B4 | 110072 | 3061 | 0.592 | 0.5796 | No | ||
114 | SLC29A2 | 3290497 | 3094 | 0.574 | 0.5793 | No | ||
115 | PPP2R2A | 2900014 5700575 | 3120 | 0.561 | 0.5793 | No | ||
116 | EIF4G2 | 3800575 6860184 | 3224 | 0.516 | 0.5750 | No | ||
117 | ALG8 | 4150497 4780500 6290563 | 3297 | 0.489 | 0.5723 | No | ||
118 | YPEL1 | 6590435 | 3372 | 0.457 | 0.5694 | No | ||
119 | PPIB | 4280450 | 3384 | 0.454 | 0.5699 | No | ||
120 | RBBP6 | 2320129 | 3493 | 0.418 | 0.5651 | No | ||
121 | SLC4A7 | 2370056 | 3517 | 0.412 | 0.5649 | No | ||
122 | SGTA | 3940154 | 3856 | 0.308 | 0.5472 | No | ||
123 | KPNA2 | 3450114 | 4093 | 0.257 | 0.5351 | No | ||
124 | AMD1 | 6290128 | 4387 | 0.206 | 0.5196 | No | ||
125 | ATP1B3 | 6040128 | 4439 | 0.200 | 0.5174 | No | ||
126 | ADCY3 | 2350347 3440242 | 4479 | 0.195 | 0.5157 | No | ||
127 | RPS26 | 510139 | 4569 | 0.182 | 0.5113 | No | ||
128 | ILF2 | 2900253 | 4717 | 0.163 | 0.5037 | No | ||
129 | HRAS | 1980551 | 4771 | 0.157 | 0.5013 | No | ||
130 | ATP5G3 | 4230551 | 4782 | 0.156 | 0.5011 | No | ||
131 | RNASEH1 | 3840575 | 4818 | 0.153 | 0.4996 | No | ||
132 | SYNCRIP | 1690195 3140113 4670279 | 5008 | 0.136 | 0.4896 | No | ||
133 | PSMA6 | 50609 | 5043 | 0.133 | 0.4881 | No | ||
134 | METTL1 | 4540670 5860162 7040433 | 5075 | 0.131 | 0.4868 | No | ||
135 | PPIF | 1740059 | 5462 | 0.104 | 0.4660 | No | ||
136 | CCNB1 | 4590433 4780372 | 5661 | 0.093 | 0.4555 | No | ||
137 | RRS1 | 4560551 | 5791 | 0.087 | 0.4487 | No | ||
138 | VCP | 5340168 | 5982 | 0.079 | 0.4386 | No | ||
139 | IDI1 | 1450736 | 6330 | 0.067 | 0.4198 | No | ||
140 | SSB | 460286 3140717 | 6460 | 0.063 | 0.4130 | No | ||
141 | PTDSS1 | 6020215 | 7089 | 0.046 | 0.3790 | No | ||
142 | SFRS1 | 2360440 | 7351 | 0.041 | 0.3649 | No | ||
143 | DNAJA1 | 1660010 2320358 6840136 | 7463 | 0.039 | 0.3589 | No | ||
144 | GJB1 | 1240441 | 7631 | 0.035 | 0.3499 | No | ||
145 | FDFT1 | 5340039 | 7687 | 0.034 | 0.3470 | No | ||
146 | MPHOSPH10 | 6860114 | 7938 | 0.029 | 0.3335 | No | ||
147 | XPO1 | 540707 | 7976 | 0.029 | 0.3316 | No | ||
148 | HSPA8 | 2120315 1050132 6550746 | 8542 | 0.020 | 0.3009 | No | ||
149 | GRIN2A | 6550538 | 8597 | 0.019 | 0.2980 | No | ||
150 | DNAJB6 | 2810309 5570451 | 8624 | 0.018 | 0.2966 | No | ||
151 | BCAP31 | 1190520 | 8865 | 0.014 | 0.2836 | No | ||
152 | ARMET | 5130670 | 9005 | 0.012 | 0.2761 | No | ||
153 | XRCC5 | 7100286 | 9129 | 0.010 | 0.2694 | No | ||
154 | ODC1 | 5670168 | 9621 | 0.003 | 0.2427 | No | ||
155 | MTHFD1 | 5900398 6520427 | 9650 | 0.003 | 0.2412 | No | ||
156 | INHBC | 3780242 | 9701 | 0.002 | 0.2385 | No | ||
157 | PHB | 2260739 | 9723 | 0.001 | 0.2374 | No | ||
158 | RBM14 | 5340731 5690315 | 10440 | -0.010 | 0.1985 | No | ||
159 | BYSL | 3170110 | 10663 | -0.013 | 0.1864 | No | ||
160 | TDG | 2900358 2940079 | 11082 | -0.020 | 0.1637 | No | ||
161 | DHX9 | 60017 1170095 2260014 | 11358 | -0.025 | 0.1488 | No | ||
162 | ZMPSTE24 | 1090112 2030593 3780129 4590044 | 12119 | -0.041 | 0.1076 | No | ||
163 | SNRPB2 | 5720577 | 12393 | -0.048 | 0.0929 | No | ||
164 | MMP15 | 5900717 | 12443 | -0.049 | 0.0903 | No | ||
165 | POLR2C | 1690020 | 12863 | -0.061 | 0.0677 | No | ||
166 | ERF | 110551 1770278 | 13033 | -0.067 | 0.0587 | No | ||
167 | CALR | 510446 | 13085 | -0.069 | 0.0561 | No | ||
168 | NP | 2630577 3120142 5670068 6290039 | 13811 | -0.106 | 0.0169 | No | ||
169 | UBE2N | 520369 2900047 | 13970 | -0.118 | 0.0086 | No | ||
170 | TARDBP | 870390 2350093 | 13980 | -0.119 | 0.0084 | No | ||
171 | CDC20 | 3440017 3440044 6220088 | 14033 | -0.123 | 0.0059 | No | ||
172 | GCDH | 2190324 4280347 | 14080 | -0.127 | 0.0037 | No | ||
173 | DOK4 | 4060452 | 14301 | -0.147 | -0.0079 | No | ||
174 | SNRPA1 | 1050735 6110131 | 14482 | -0.165 | -0.0172 | No | ||
175 | EBNA1BP2 | 50369 1400433 6040019 | 14634 | -0.189 | -0.0250 | No | ||
176 | RABGGTB | 3120037 | 15087 | -0.288 | -0.0489 | No | ||
177 | PSMD11 | 2340538 6510053 | 15242 | -0.337 | -0.0564 | No | ||
178 | HNRPAB | 540504 | 15345 | -0.371 | -0.0610 | No | ||
179 | SC4MOL | 3140524 | 15410 | -0.394 | -0.0635 | No | ||
180 | ACAT2 | 2680400 3610440 | 15689 | -0.515 | -0.0773 | No | ||
181 | ME2 | 5080121 | 15701 | -0.523 | -0.0766 | No | ||
182 | EIF2B4 | 5270082 | 15877 | -0.605 | -0.0847 | No | ||
183 | ADRM1 | 670333 5690162 | 15971 | -0.656 | -0.0881 | No | ||
184 | PFN1 | 6130132 | 16033 | -0.689 | -0.0897 | No | ||
185 | HNRPL | 4210593 | 16052 | -0.697 | -0.0889 | No | ||
186 | SQLE | 50180 940092 | 16108 | -0.736 | -0.0901 | No | ||
187 | OGFR | 5700397 | 16122 | -0.748 | -0.0889 | No | ||
188 | ACLY | 1740609 | 16139 | -0.754 | -0.0879 | No | ||
189 | SEC61B | 840113 4540687 | 16201 | -0.795 | -0.0893 | No | ||
190 | PABPN1 | 460519 | 16210 | -0.806 | -0.0877 | No | ||
191 | GOLGA1 | 5860471 | 16341 | -0.905 | -0.0925 | No | ||
192 | TOP1 | 770471 4060632 6650324 | 16388 | -0.933 | -0.0927 | No | ||
193 | HSPA4 | 1050170 3450309 | 16426 | -0.960 | -0.0923 | No | ||
194 | PCBP1 | 1050088 | 16436 | -0.964 | -0.0904 | No | ||
195 | PFKP | 70138 6760040 1170278 | 16468 | -0.985 | -0.0897 | No | ||
196 | HNRPA2B1 | 1240619 6200161 6200494 6980408 | 16491 | -0.998 | -0.0884 | No | ||
197 | COG2 | 5900129 | 16643 | -1.101 | -0.0938 | No | ||
198 | UBE2G2 | 1240035 3870184 | 16715 | -1.166 | -0.0948 | No | ||
199 | DHCR7 | 1470138 | 16736 | -1.185 | -0.0929 | No | ||
200 | CHD4 | 5420059 6130338 6380717 | 16744 | -1.194 | -0.0904 | No | ||
201 | IDH1 | 1990021 | 16747 | -1.195 | -0.0875 | No | ||
202 | MAZ | 3360121 6940750 | 16753 | -1.204 | -0.0848 | No | ||
203 | PRPF4 | 430301 2970364 | 16797 | -1.252 | -0.0840 | No | ||
204 | SFPQ | 4760110 | 16918 | -1.375 | -0.0871 | No | ||
205 | CLIC1 | 110600 | 17016 | -1.469 | -0.0887 | No | ||
206 | MRPL23 | 4070142 | 17028 | -1.483 | -0.0856 | No | ||
207 | MYD88 | 2100717 | 17076 | -1.543 | -0.0844 | No | ||
208 | SRRM1 | 6110025 | 17118 | -1.597 | -0.0826 | No | ||
209 | EBP | 2760292 | 17153 | -1.644 | -0.0804 | No | ||
210 | RANGAP1 | 2320593 6650601 | 17194 | -1.699 | -0.0783 | No | ||
211 | PTPN6 | 4230128 | 17289 | -1.812 | -0.0789 | No | ||
212 | LIMK2 | 2650446 4050164 | 17428 | -2.030 | -0.0814 | No | ||
213 | EIF5A | 1500059 5290022 6370026 | 17614 | -2.334 | -0.0857 | No | ||
214 | SRPK1 | 450110 | 17663 | -2.414 | -0.0823 | No | ||
215 | MYST1 | 2190397 | 17669 | -2.421 | -0.0765 | No | ||
216 | PPP1R10 | 110136 3170725 3610484 | 17700 | -2.506 | -0.0719 | No | ||
217 | MAP3K11 | 7000039 | 17924 | -2.956 | -0.0767 | No | ||
218 | ERH | 1770156 4570148 | 17928 | -2.964 | -0.0695 | No | ||
219 | TAP1 | 4050047 | 18042 | -3.321 | -0.0674 | No | ||
220 | ARS2 | 2370348 4920577 6840427 | 18100 | -3.544 | -0.0617 | No | ||
221 | STAT1 | 6510204 6590553 | 18110 | -3.562 | -0.0533 | No | ||
222 | ADAM19 | 5340075 | 18159 | -3.747 | -0.0466 | No | ||
223 | DYRK1A | 3190181 | 18286 | -4.333 | -0.0427 | No | ||
224 | HS6ST1 | 4760373 | 18402 | -5.082 | -0.0363 | No | ||
225 | DNAJB1 | 1090041 | 18430 | -5.350 | -0.0244 | No | ||
226 | XBP1 | 3840594 | 18551 | -6.754 | -0.0142 | No | ||
227 | PRODH | 1240452 | 18566 | -7.101 | 0.0027 | No |