Details for gene set HSA04660_T_CELL_RECEPTOR_SIGNALING

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	HSA04660_T_CELL_RECEPTOR_SIGNALING_PATHWAY
Enrichment Score (ES)	-0.6199444
Normalized Enrichment Score (NES)	-1.5842997
Nominal p-value	0.0
FDR q-value	0.26066443
FWER p-Value	0.978

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GRB2	6650398	481	3.303	0.0024	No
2	NFKBIB	2260167	687	2.854	0.0158	No
3	PIK3R3	1770333	789	2.640	0.0330	No
4	PIK3R2	1660193	807	2.604	0.0544	No
5	PTPRC	130402 5290148	1532	1.647	0.0295	No
6	PPP3CB	6020156	1587	1.586	0.0402	No
7	IL5	6370364 1050193	1588	1.585	0.0538	No
8	PPP3R1	1190041 1570487	1592	1.581	0.0672	No
9	IL10	2340685 2640541 2850403 6590286	1851	1.361	0.0649	No
10	KRAS	2060170	2251	1.026	0.0522	No
11	NFKB1	5420358	2462	0.934	0.0489	No
12	CD8B	1940411 2570035	2590	0.852	0.0493	No
13	RASGRP1	1050148 4050632 6510671	3333	0.474	0.0133	No
14	NRAS	6900577	3508	0.415	0.0075	No
15	CHUK	7050736	3694	0.353	0.0005	No
16	CDC42	1240168 3440278 4480519 5290162	4538	0.186	-0.0434	No
17	NFAT5	2510411 5890195 6550152	4702	0.165	-0.0507	No
18	HRAS	1980551	4771	0.157	-0.0531	No
19	TNF	6650603	4857	0.148	-0.0564	No
20	PPP3CA	4760332 6760092	5002	0.136	-0.0630	No
21	PLCG1	6020369	5644	0.094	-0.0968	No
22	IL4	6020537	6040	0.077	-0.1174	No
23	NFATC4	2470735	6245	0.070	-0.1278	No
24	PDCD1	4120082	6453	0.063	-0.1385	No
25	PAK3	4210136	6598	0.059	-0.1457	No
26	GRAP2	7100441 1410647	6704	0.056	-0.1509	No
27	PIK3R1	4730671	7432	0.039	-0.1898	No
28	PPP3R2	7000154	7563	0.037	-0.1965	No
29	AKT1	5290746	7793	0.032	-0.2086	No
30	IL2	1770725	8133	0.026	-0.2267	No
31	PIK3CB	3800600	9319	0.007	-0.2906	No
32	CSF2	1660593	9335	0.007	-0.2914	No
33	CBLC	50152	9748	0.001	-0.3136	No
34	NFATC2	70450 540097	9799	0.000	-0.3163	No
35	PRKCQ	2260170 3870193	10603	-0.012	-0.3595	No
36	CD40LG	3120270	10691	-0.014	-0.3641	No
37	PAK7	3830164	10835	-0.016	-0.3717	No
38	PAK1	4540315	11100	-0.020	-0.3858	No
39	SOS1	7050338	11112	-0.021	-0.3862	No
40	JUN	840170	11408	-0.026	-0.4019	No
41	NFKBIE	580390 2190086	11468	-0.027	-0.4048	No
42	CTLA4	6590537	11494	-0.028	-0.4059	No
43	IFNG	5670592	11703	-0.032	-0.4169	No
44	MALT1	4670292	11838	-0.034	-0.4238	No
45	NCK1	6200575 6510050	12465	-0.049	-0.4572	No
46	AKT2	3850541 3870519	12629	-0.054	-0.4655	No
47	PIK3CA	6220129	12692	-0.056	-0.4684	No
48	FOS	1850315	14050	-0.124	-0.5406	No
49	NCK2	2510010	14343	-0.150	-0.5550	No
50	CBLB	3520465 4670348	14969	-0.256	-0.5866	No
51	NFATC1	510400 2320348 4050600 6180161 6290136 6620086	15011	-0.268	-0.5865	No
52	SOS2	2060722	15106	-0.293	-0.5891	No
53	PAK2	360438 7050068	15518	-0.438	-0.6075	No
54	IKBKG	3450092 3840377 6590592	15750	-0.544	-0.6153	Yes
55	CDK4	540075 4540600	15811	-0.575	-0.6136	Yes
56	VAV3	1050731 2450242 2680653	15836	-0.584	-0.6099	Yes
57	AKT3	1580270 3290278	15882	-0.607	-0.6071	Yes
58	FYN	2100468 4760520 4850687	15899	-0.618	-0.6026	Yes
59	PDK1	5290427	15965	-0.653	-0.6006	Yes
60	MAP3K8	2940286	15987	-0.666	-0.5960	Yes
61	ZAP70	1410494 2260504	16100	-0.731	-0.5957	Yes
62	VAV2	3610725 5890717	16146	-0.756	-0.5917	Yes
63	LCP2	2680066 6650707	16233	-0.826	-0.5892	Yes
64	ICOS	1190048	16269	-0.855	-0.5838	Yes
65	PIK3R5	1090056	16359	-0.914	-0.5808	Yes
66	PPP3CC	2450139	16390	-0.935	-0.5744	Yes
67	IKBKB	6840072	16418	-0.950	-0.5677	Yes
68	PIK3CG	5890110	17009	-1.462	-0.5870	Yes
69	PAK4	1690152	17070	-1.536	-0.5770	Yes
70	LAT	3170025	17151	-1.641	-0.5673	Yes
71	RHOA	580142 5900131 5340450	17225	-1.731	-0.5564	Yes
72	PTPN6	4230128	17289	-1.812	-0.5442	Yes
73	NFKBIA	1570152	17332	-1.860	-0.5305	Yes
74	MAP3K14	5890435	17399	-1.981	-0.5171	Yes
75	NFATC3	5050520	17575	-2.268	-0.5071	Yes
76	NFKB2	2320670	17622	-2.349	-0.4894	Yes
77	CBL	6380068	17677	-2.437	-0.4714	Yes
78	CD28	1400739 4210093	17736	-2.566	-0.4525	Yes
79	LCK	3360142	17786	-2.667	-0.4323	Yes
80	PIK3CD	3060546	17832	-2.774	-0.4109	Yes
81	BCL10	2360397	18080	-3.458	-0.3946	Yes
82	VAV1	6020487	18137	-3.653	-0.3663	Yes
83	CD4	1090010	18290	-4.362	-0.3371	Yes
84	CD3D	2810739	18306	-4.485	-0.2994	Yes
85	CARD11	70338	18363	-4.788	-0.2613	Yes
86	CD3E	3800056	18448	-5.536	-0.2184	Yes
87	CD247	3800725 5720136	18488	-5.985	-0.1691	Yes
88	ITK	2230592	18492	-6.023	-0.1176	Yes
89	CD3G	2680288	18554	-6.817	-0.0624	Yes
90	TEC	1400576	18580	-7.663	0.0019	Yes