Details for gene set BRENTANI

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	BRENTANI_SIGNALING
Enrichment Score (ES)	-0.6026088
Normalized Enrichment Score (NES)	-1.6316268
Nominal p-value	0.0
FDR q-value	0.30482557
FWER p-Value	0.785

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAP3K7IP1	2120095 5890452 6040167	618	2.985	-0.0169	No
2	STAT5A	2680458	695	2.835	-0.0054	No
3	TNFSF13	2650170	764	2.700	0.0059	No
4	IL12RB1	2230338 5420053	927	2.406	0.0105	No
5	MAPK10	6110193	1378	1.835	-0.0037	No
6	MAPK13	6760215	1544	1.634	-0.0036	No
7	ITGA9	670180	1600	1.578	0.0021	No
8	SMO	5340538 6350132	1670	1.529	0.0069	No
9	AXL	1770095	1677	1.523	0.0150	No
10	MAP2K4	5130133	1700	1.499	0.0221	No
11	ITGB5	70129	1743	1.453	0.0279	No
12	CXCL1	2690537	1757	1.439	0.0352	No
13	GRB7	2100471	1774	1.423	0.0422	No
14	IL10	2340685 2640541 2850403 6590286	1851	1.361	0.0456	No
15	MAPKAPK2	2850500	1878	1.333	0.0516	No
16	JAG2	1500341	1934	1.280	0.0557	No
17	ITGB1	5080156 6270528	1985	1.231	0.0598	No
18	TYRO3	3130193	2436	0.948	0.0407	No
19	BTK	3130044	2440	0.945	0.0458	No
20	MAP2K2	4590601	2445	0.943	0.0508	No
21	RAF1	1770600	2612	0.832	0.0464	No
22	ABL1	1050593 2030050 4010114	2989	0.624	0.0295	No
23	YWHAE	5310435	3098	0.572	0.0268	No
24	CAMK4	1690091	3191	0.529	0.0247	No
25	NRAS	6900577	3508	0.415	0.0099	No
26	NOTCH4	2450040 6370707	3682	0.357	0.0025	No
27	TNFSF4	3940594	4036	0.269	-0.0152	No
28	IL1B	2640364	4058	0.263	-0.0148	No
29	TANK	1090020 2060458 2370400	4168	0.242	-0.0194	No
30	MAPK1	3190193 6200253	4254	0.228	-0.0227	No
31	BCR	2260020 4230180 6040195	4378	0.208	-0.0283	No
32	TNFRSF10B	940671 1500451 6550768 6900500	4567	0.182	-0.0374	No
33	ITGA3	4570427	4656	0.171	-0.0413	No
34	HRAS	1980551	4771	0.157	-0.0466	No
35	PTCH2	2900092	4790	0.155	-0.0467	No
36	TNF	6650603	4857	0.148	-0.0494	No
37	ERG	50154 1770739	4972	0.138	-0.0548	No
38	MCC	620750	5001	0.136	-0.0556	No
39	CXCL2	610398	5126	0.126	-0.0616	No
40	IL13	7040021	5348	0.110	-0.0730	No
41	IFNB1	1400142	5467	0.103	-0.0788	No
42	ARHGEF16	3990372	5638	0.094	-0.0875	No
43	TNFRSF1B	3990035 5860372	5701	0.091	-0.0904	No
44	CALM1	380128	5723	0.090	-0.0910	No
45	ITGA4	2470739	5759	0.089	-0.0924	No
46	MAP2K7	2260086	5956	0.081	-0.1026	No
47	INHA	6100102	6183	0.072	-0.1144	No
48	WNT4	4150619	6487	0.062	-0.1305	No
49	SUFU	6650181	6614	0.058	-0.1370	No
50	TTK	3800129	6731	0.055	-0.1430	No
51	ARHGAP6	2060121	6942	0.049	-0.1541	No
52	MPL	2360253	7291	0.042	-0.1728	No
53	MAP3K4	5720041	7339	0.041	-0.1751	No
54	IGFBP3	2370500	7462	0.039	-0.1815	No
55	MAPK11	130452 3120440 3610465	7587	0.036	-0.1880	No
56	AKT1	5290746	7793	0.032	-0.1989	No
57	ITGA7	1230739	7796	0.032	-0.1989	No
58	MAP2K1	840739	8058	0.027	-0.2129	No
59	RAP1A	1090025	8179	0.025	-0.2192	No
60	ARHGEF12	3990195	8866	0.014	-0.2563	No
61	SKIL	1090364	8953	0.013	-0.2609	No
62	WNT1	4780148	8973	0.012	-0.2619	No
63	ROS1	1090019	9402	0.006	-0.2850	No
64	ITGAM	1190373	9445	0.006	-0.2873	No
65	MAS1	2650600	9498	0.005	-0.2901	No
66	GRB14	510035 3060369	9506	0.005	-0.2904	No
67	ITGAV	2340020	9652	0.003	-0.2983	No
68	RAN	2260446 4590647	9782	0.000	-0.3053	No
69	MAPKAPK5	2510601	9793	0.000	-0.3058	No
70	MAP3K12	2470373 6420162	9831	-0.000	-0.3078	No
71	WNT5A	840685 3120152	10056	-0.004	-0.3199	No
72	IGFBP1	5720435	10170	-0.006	-0.3260	No
73	MUSK	1190113	10174	-0.006	-0.3261	No
74	MAPK7	5670079 6100128	10299	-0.008	-0.3328	No
75	MAPK12	450022 1340717 7050484	10519	-0.011	-0.3446	No
76	ABL2	580021	10533	-0.011	-0.3453	No
77	ITGAX	6130524	11006	-0.019	-0.3708	No
78	SOS1	7050338	11112	-0.021	-0.3763	No
79	MAPK4	870142	11478	-0.027	-0.3960	No
80	WNT2	4610020	11624	-0.030	-0.4037	No
81	IFNG	5670592	11703	-0.032	-0.4077	No
82	APC	3850484 5860722	11823	-0.034	-0.4140	No
83	ATM	3610110 4050524	11988	-0.038	-0.4226	No
84	JAG1	3440390	12194	-0.043	-0.4335	No
85	NCK1	6200575 6510050	12465	-0.049	-0.4479	No
86	SRC	580132	12487	-0.050	-0.4487	No
87	AKT2	3850541 3870519	12629	-0.054	-0.4561	No
88	NF1	6980433	12727	-0.057	-0.4610	No
89	SYK	6940133	12894	-0.062	-0.4697	No
90	STAT6	1190010 5720019	12978	-0.065	-0.4738	No
91	IRS1	1190204	13294	-0.077	-0.4905	No
92	REL	360707	13327	-0.079	-0.4918	No
93	MAP3K5	6020041 6380162	13361	-0.080	-0.4931	No
94	IL15	4560332 5860438	13582	-0.092	-0.5045	No
95	ITGB7	4670619	13597	-0.093	-0.5048	No
96	BIRC2	2940435 4730020	13602	-0.093	-0.5045	No
97	PTPRK	1450433 2640142	13855	-0.109	-0.5175	No
98	IFNAR1	4730672	13856	-0.110	-0.5169	No
99	SHC1	2900731 3170504 6520537	13933	-0.115	-0.5204	No
100	DLG1	2630091 6020286	13942	-0.116	-0.5202	No
101	VIPR1	2480292 5720288 6760537	14525	-0.171	-0.5508	No
102	ARHGAP1	2810010 5270064	14656	-0.191	-0.5568	No
103	ITGB4	1740021 3840482	14739	-0.205	-0.5601	No
104	CXCL12	580546 4150750 4570068	14911	-0.240	-0.5680	No
105	STAT5B	6200026	14990	-0.263	-0.5708	No
106	JAK3	70347 3290008	15141	-0.301	-0.5773	No
107	ILK	870601 4480180	15143	-0.302	-0.5756	No
108	SFN	6290301 7510608	15176	-0.314	-0.5756	No
109	TIAM1	5420288	15194	-0.320	-0.5748	No
110	ITGA5	5550520	15241	-0.337	-0.5754	No
111	ITGB3	5270463	15316	-0.362	-0.5774	No
112	IL18R1	270546	15526	-0.442	-0.5863	No
113	IKBKG	3450092 3840377 6590592	15750	-0.544	-0.5953	No
114	ITGAE	4210632 4670239 5340253 5420746 5690154 5700685 6770154	15760	-0.549	-0.5928	No
115	FYN	2100468 4760520 4850687	15899	-0.618	-0.5968	No
116	MAP3K8	2940286	15987	-0.666	-0.5979	Yes
117	JAK1	5910746	15995	-0.673	-0.5945	Yes
118	ZAP70	1410494 2260504	16100	-0.731	-0.5961	Yes
119	ROCK1	130044	16180	-0.781	-0.5960	Yes
120	MAP2K3	5570193	16214	-0.811	-0.5933	Yes
121	TRAF6	4810292 6200132	16386	-0.933	-0.5974	Yes
122	MAP4K4	2360059	16478	-0.991	-0.5969	Yes
123	MAPK9	2060273 3780209 4070397	16489	-0.997	-0.5919	Yes
124	RALBP1	4780632	16595	-1.057	-0.5917	Yes
125	SH3BP2	610131	16610	-1.072	-0.5865	Yes
126	CRK	1230162 4780128	16625	-1.085	-0.5813	Yes
127	TYK2	1660465 1740736	16700	-1.152	-0.5789	Yes
128	MAP2K5	2030440	16809	-1.262	-0.5778	Yes
129	PTEN	3390064	16842	-1.294	-0.5723	Yes
130	PIK3C3	6590717	16870	-1.323	-0.5665	Yes
131	MKNK1	6510161	16909	-1.359	-0.5610	Yes
132	RGS16	780091	16978	-1.426	-0.5568	Yes
133	PIK3CG	5890110	17009	-1.462	-0.5503	Yes
134	MYD88	2100717	17076	-1.543	-0.5453	Yes
135	IL2RB	4730072	17155	-1.650	-0.5404	Yes
136	RASA1	1240315	17172	-1.670	-0.5320	Yes
137	IL6ST	5890047	17300	-1.822	-0.5288	Yes
138	DGKA	5720152 5890328	17359	-1.901	-0.5214	Yes
139	AXIN2	3850131	17364	-1.910	-0.5110	Yes
140	MAP3K14	5890435	17399	-1.981	-0.5019	Yes
141	GNB1	2120397	17416	-2.005	-0.4916	Yes
142	RELB	1400048	17503	-2.129	-0.4845	Yes
143	TNFRSF4	6840056	17531	-2.172	-0.4739	Yes
144	MAP2K6	1230056 2940204	17557	-2.234	-0.4629	Yes
145	RELA	3830075	17641	-2.379	-0.4542	Yes
146	AXIN1	3360358 6940451	17705	-2.509	-0.4437	Yes
147	ITGA6	3830129	17748	-2.591	-0.4316	Yes
148	STAT2	3780519	18002	-3.197	-0.4276	Yes
149	ITGB2	6380348	18049	-3.332	-0.4116	Yes
150	BCL10	2360397	18080	-3.458	-0.3941	Yes
151	STAT1	6510204 6590553	18110	-3.562	-0.3759	Yes
152	VAV1	6020487	18137	-3.653	-0.3571	Yes
153	TNFRSF14	5050438	18147	-3.690	-0.3371	Yes
154	CRKL	4050427	18162	-3.756	-0.3171	Yes
155	DGKQ	2480609	18185	-3.849	-0.2969	Yes
156	ITGAL	1450324	18187	-3.859	-0.2756	Yes
157	IFNGR1	610577	18189	-3.860	-0.2542	Yes
158	PDPK1	6650168	18190	-3.862	-0.2328	Yes
159	NOTCH3	3060603	18258	-4.178	-0.2133	Yes
160	STAT3	460040 3710341	18266	-4.219	-0.1903	Yes
161	TRAF1	3440735	18280	-4.295	-0.1672	Yes
162	MAP3K3	610685	18320	-4.550	-0.1441	Yes
163	TRAF3	5690647	18398	-5.069	-0.1202	Yes
164	IFNAR2	4070687 7100484	18401	-5.079	-0.0921	Yes
165	TNFRSF1A	1090390 6520735	18474	-5.755	-0.0641	Yes
166	PTK2B	4730411	18527	-6.405	-0.0314	Yes
167	DGKG	1770025	18536	-6.531	0.0043	Yes