Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | REACTOME_GENE_EXPRESSION |
Enrichment Score (ES) | 0.6282883 |
Normalized Enrichment Score (NES) | 1.7217789 |
Nominal p-value | 0.0 |
FDR q-value | 0.023291158 |
FWER p-Value | 0.097 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EIF2S2 | 770095 2810487 | 26 | 7.527 | 0.0396 | Yes | ||
2 | U2AF1 | 5130292 | 56 | 6.059 | 0.0710 | Yes | ||
3 | RARS | 380390 | 105 | 5.267 | 0.0970 | Yes | ||
4 | METTL3 | 360497 | 138 | 4.992 | 0.1224 | Yes | ||
5 | EIF4B | 5390563 5270577 | 144 | 4.909 | 0.1489 | Yes | ||
6 | RPS3A | 2470086 | 166 | 4.747 | 0.1736 | Yes | ||
7 | NARS | 1660722 | 202 | 4.500 | 0.1962 | Yes | ||
8 | NUP93 | 2190273 | 229 | 4.326 | 0.2183 | Yes | ||
9 | CCNH | 3190347 | 389 | 3.617 | 0.2294 | Yes | ||
10 | GARS | 1230601 | 425 | 3.520 | 0.2466 | Yes | ||
11 | TCEB1 | 1170619 | 447 | 3.431 | 0.2642 | Yes | ||
12 | RPS19 | 5860066 | 470 | 3.345 | 0.2812 | Yes | ||
13 | ETF1 | 6770075 | 490 | 3.269 | 0.2979 | Yes | ||
14 | GTF2H2 | 5130358 | 510 | 3.235 | 0.3145 | Yes | ||
15 | CPSF1 | 6290064 | 558 | 3.130 | 0.3290 | Yes | ||
16 | TXNL4A | 4120286 6510242 | 606 | 3.022 | 0.3429 | Yes | ||
17 | PHF5A | 2690519 | 652 | 2.899 | 0.3562 | Yes | ||
18 | RPS24 | 5420377 | 733 | 2.747 | 0.3669 | Yes | ||
19 | SFRS6 | 60224 | 743 | 2.731 | 0.3812 | Yes | ||
20 | SNRPF | 3170280 | 754 | 2.717 | 0.3955 | Yes | ||
21 | POLR2I | 4060400 | 773 | 2.673 | 0.4090 | Yes | ||
22 | SF3A3 | 6660603 | 793 | 2.637 | 0.4224 | Yes | ||
23 | YBX1 | 1340039 4730500 | 798 | 2.627 | 0.4364 | Yes | ||
24 | AARS | 1570279 2370136 | 811 | 2.592 | 0.4499 | Yes | ||
25 | CCAR1 | 3190092 | 832 | 2.558 | 0.4627 | Yes | ||
26 | POLR2E | 2900348 3360348 | 977 | 2.327 | 0.4676 | Yes | ||
27 | EIF2B1 | 4610082 7040242 | 1002 | 2.298 | 0.4788 | Yes | ||
28 | EIF4A1 | 1990341 2810300 | 1010 | 2.286 | 0.4909 | Yes | ||
29 | NUP43 | 3360482 | 1129 | 2.156 | 0.4962 | Yes | ||
30 | RAE1 | 7050121 | 1136 | 2.145 | 0.5076 | Yes | ||
31 | SFRS9 | 3800047 | 1262 | 1.978 | 0.5116 | Yes | ||
32 | CCNC | 3390750 | 1347 | 1.885 | 0.5173 | Yes | ||
33 | EIF2B2 | 4290048 | 1384 | 1.830 | 0.5253 | Yes | ||
34 | SNRPD2 | 6110035 | 1403 | 1.796 | 0.5341 | Yes | ||
35 | RPL38 | 70040 4060138 6200601 | 1465 | 1.722 | 0.5401 | Yes | ||
36 | RPL14 | 5080471 | 1487 | 1.695 | 0.5482 | Yes | ||
37 | EIF4G1 | 4070446 | 1608 | 1.575 | 0.5503 | Yes | ||
38 | RPS23 | 7100594 | 1740 | 1.455 | 0.5511 | Yes | ||
39 | POLR2H | 5890242 | 1773 | 1.425 | 0.5571 | Yes | ||
40 | U2AF2 | 450600 4670128 5420292 | 1806 | 1.393 | 0.5630 | Yes | ||
41 | GTF2H3 | 50600 | 1881 | 1.328 | 0.5662 | Yes | ||
42 | SF3A2 | 3140500 | 1920 | 1.295 | 0.5712 | Yes | ||
43 | NUP62 | 1240128 | 1966 | 1.249 | 0.5756 | Yes | ||
44 | GTF2E2 | 4010441 | 1987 | 1.229 | 0.5812 | Yes | ||
45 | RPL5 | 840095 | 2014 | 1.203 | 0.5863 | Yes | ||
46 | RNMT | 1770500 | 2022 | 1.199 | 0.5924 | Yes | ||
47 | NUP160 | 1990551 | 2080 | 1.158 | 0.5957 | Yes | ||
48 | SFRS2 | 50707 380593 | 2242 | 1.028 | 0.5925 | Yes | ||
49 | RPL27A | 3130451 110195 6840494 | 2322 | 1.000 | 0.5937 | Yes | ||
50 | CSTF1 | 4610129 | 2332 | 0.999 | 0.5987 | Yes | ||
51 | RBM5 | 3520402 5270121 | 2345 | 0.997 | 0.6034 | Yes | ||
52 | EIF5 | 6380750 | 2465 | 0.931 | 0.6020 | Yes | ||
53 | SFRS3 | 770315 4230593 | 2473 | 0.924 | 0.6067 | Yes | ||
54 | TBP | 1450601 2810193 | 2558 | 0.871 | 0.6069 | Yes | ||
55 | RPLP2 | 5290020 | 2653 | 0.809 | 0.6062 | Yes | ||
56 | NUPL2 | 6550537 | 2656 | 0.807 | 0.6105 | Yes | ||
57 | EEF1G | 3940603 | 2759 | 0.740 | 0.6090 | Yes | ||
58 | DNAJC8 | 4050075 | 2819 | 0.712 | 0.6097 | Yes | ||
59 | EEF1E1 | 4540711 | 2850 | 0.695 | 0.6118 | Yes | ||
60 | YARS | 70739 | 2877 | 0.681 | 0.6141 | Yes | ||
61 | TAF12 | 3710746 4920300 6180603 | 2923 | 0.662 | 0.6153 | Yes | ||
62 | RPS15A | 1170180 | 2946 | 0.651 | 0.6176 | Yes | ||
63 | TAF11 | 5720538 | 2986 | 0.625 | 0.6189 | Yes | ||
64 | RPS2 | 1340647 | 3005 | 0.619 | 0.6213 | Yes | ||
65 | RNGTT | 780152 780746 1090471 | 3012 | 0.614 | 0.6243 | Yes | ||
66 | SNRPG | 2340551 | 3041 | 0.601 | 0.6261 | Yes | ||
67 | SF3B4 | 110072 | 3061 | 0.592 | 0.6283 | Yes | ||
68 | FARS2 | 5340575 | 3125 | 0.558 | 0.6279 | No | ||
69 | MED6 | 6840500 | 3300 | 0.487 | 0.6211 | No | ||
70 | RPL4 | 2940014 5420324 | 3340 | 0.471 | 0.6216 | No | ||
71 | RPL18A | 4570619 | 3400 | 0.449 | 0.6208 | No | ||
72 | NUDT21 | 1240167 | 3411 | 0.446 | 0.6227 | No | ||
73 | RDBP | 6590044 | 3464 | 0.429 | 0.6222 | No | ||
74 | GTF2H1 | 2570746 2650148 | 3831 | 0.315 | 0.6041 | No | ||
75 | SNRPB | 1230097 2940086 3520671 | 3963 | 0.283 | 0.5986 | No | ||
76 | RARS2 | 5570524 6290497 6900332 | 3985 | 0.278 | 0.5990 | No | ||
77 | RPL8 | 20296 | 4030 | 0.270 | 0.5981 | No | ||
78 | POLR2J | 7100372 | 4198 | 0.236 | 0.5903 | No | ||
79 | RPL27 | 1940088 | 4309 | 0.221 | 0.5855 | No | ||
80 | MAGOH | 2370373 5050068 | 4343 | 0.215 | 0.5849 | No | ||
81 | RPS21 | 3120673 | 4354 | 0.214 | 0.5855 | No | ||
82 | POLR2A | 5220647 | 4360 | 0.213 | 0.5864 | No | ||
83 | SNW1 | 4010736 | 4527 | 0.187 | 0.5785 | No | ||
84 | RPLP1 | 3140292 | 4620 | 0.175 | 0.5744 | No | ||
85 | PTBP1 | 4070736 | 4661 | 0.171 | 0.5732 | No | ||
86 | RPS13 | 1570364 | 4862 | 0.148 | 0.5632 | No | ||
87 | RANBP2 | 4280338 | 4977 | 0.138 | 0.5578 | No | ||
88 | RPL6 | 6040735 | 5020 | 0.135 | 0.5562 | No | ||
89 | TAF9 | 1850458 3830136 | 5068 | 0.131 | 0.5544 | No | ||
90 | EEF2 | 1050369 4670035 5890598 | 5137 | 0.125 | 0.5514 | No | ||
91 | EIF2S1 | 5360292 | 5490 | 0.101 | 0.5329 | No | ||
92 | RPS29 | 580324 | 5556 | 0.098 | 0.5299 | No | ||
93 | EPRS | 3170301 | 6554 | 0.060 | 0.4762 | No | ||
94 | SFRS1 | 2360440 | 7351 | 0.041 | 0.4334 | No | ||
95 | RNPS1 | 610736 1090021 | 7551 | 0.037 | 0.4228 | No | ||
96 | CDK7 | 2640451 | 7747 | 0.033 | 0.4124 | No | ||
97 | RPL17 | 2690167 5690504 | 8638 | 0.018 | 0.3643 | No | ||
98 | POLR2B | 3780138 | 8831 | 0.015 | 0.3540 | No | ||
99 | HARS | 6100487 | 9177 | 0.009 | 0.3354 | No | ||
100 | CCNT2 | 2100390 4150563 | 9605 | 0.003 | 0.3123 | No | ||
101 | TPR | 1990066 6550390 | 10130 | -0.005 | 0.2840 | No | ||
102 | GTF2A2 | 2230184 | 10188 | -0.006 | 0.2809 | No | ||
103 | NUP54 | 940546 2360156 4060278 | 11088 | -0.020 | 0.2324 | No | ||
104 | NUP153 | 7000452 | 11304 | -0.024 | 0.2208 | No | ||
105 | TAF4 | 1450170 | 11337 | -0.025 | 0.2192 | No | ||
106 | DHX9 | 60017 1170095 2260014 | 11358 | -0.025 | 0.2183 | No | ||
107 | EIF5B | 1190102 4200440 | 11393 | -0.026 | 0.2166 | No | ||
108 | SNRPB2 | 5720577 | 12393 | -0.048 | 0.1628 | No | ||
109 | POLR2C | 1690020 | 12863 | -0.061 | 0.1377 | No | ||
110 | NUP35 | 5340408 | 13244 | -0.075 | 0.1176 | No | ||
111 | SF3B1 | 7000632 | 13414 | -0.082 | 0.1089 | No | ||
112 | RPL18 | 6380181 3870195 | 13705 | -0.099 | 0.0937 | No | ||
113 | RPL41 | 6940112 | 13829 | -0.107 | 0.0876 | No | ||
114 | LARS2 | 7000706 | 14105 | -0.129 | 0.0734 | No | ||
115 | SNRPA1 | 1050735 6110131 | 14482 | -0.165 | 0.0540 | No | ||
116 | NFX1 | 450504 | 14620 | -0.186 | 0.0476 | No | ||
117 | RPS28 | 3830221 | 14941 | -0.248 | 0.0316 | No | ||
118 | RPL28 | 6900136 | 14951 | -0.251 | 0.0325 | No | ||
119 | SMC1A | 3060600 5700148 5890113 6370154 | 15208 | -0.324 | 0.0204 | No | ||
120 | RPS16 | 510722 | 15209 | -0.324 | 0.0221 | No | ||
121 | EIF4E | 1580403 70133 6380215 | 15331 | -0.366 | 0.0176 | No | ||
122 | TH1L | 1190632 | 15693 | -0.518 | 0.0009 | No | ||
123 | RPS5 | 580093 | 15706 | -0.525 | 0.0031 | No | ||
124 | IARS | 460528 1580739 1690008 | 15734 | -0.537 | 0.0045 | No | ||
125 | RPL37A | 7040717 | 15752 | -0.544 | 0.0066 | No | ||
126 | FAU | 7100465 | 15800 | -0.569 | 0.0071 | No | ||
127 | RPS20 | 1740092 | 15879 | -0.606 | 0.0062 | No | ||
128 | SFRS5 | 3450176 6350008 | 15913 | -0.624 | 0.0078 | No | ||
129 | GTF2B | 6860685 | 16123 | -0.749 | 0.0006 | No | ||
130 | RPL11 | 3780435 | 16155 | -0.763 | 0.0030 | No | ||
131 | RPL19 | 5550592 | 16319 | -0.890 | -0.0009 | No | ||
132 | ERCC3 | 6900008 | 16321 | -0.891 | 0.0039 | No | ||
133 | SF3B3 | 3710044 | 16344 | -0.907 | 0.0076 | No | ||
134 | CCNT1 | 2450563 5390184 | 16513 | -1.008 | 0.0040 | No | ||
135 | ELL | 3520731 | 16592 | -1.054 | 0.0055 | No | ||
136 | PRPF8 | 1230497 1570600 | 16611 | -1.073 | 0.0104 | No | ||
137 | SF3B2 | 6590576 | 16697 | -1.150 | 0.0120 | No | ||
138 | PRPF4 | 430301 2970364 | 16797 | -1.252 | 0.0135 | No | ||
139 | TAF10 | 2760020 | 17007 | -1.459 | 0.0101 | No | ||
140 | SRRM1 | 6110025 | 17118 | -1.597 | 0.0128 | No | ||
141 | SFRS7 | 2760408 | 17122 | -1.602 | 0.0214 | No | ||
142 | EIF4EBP1 | 60132 5720148 | 17228 | -1.733 | 0.0251 | No | ||
143 | CD2BP2 | 1580301 | 17880 | -2.874 | 0.0055 | No | ||
144 | SUPT4H1 | 6200056 | 17902 | -2.914 | 0.0203 | No | ||
145 | WARS | 2570717 3290139 | 18060 | -3.371 | 0.0301 | No |