Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | absentNotch |
| GeneSet | REACTOME_G1_S_DNA_DAMAGE_CHECKPOINTS |
| Enrichment Score (ES) | 0.7098298 |
| Normalized Enrichment Score (NES) | 1.6161426 |
| Nominal p-value | 0.0020833334 |
| FDR q-value | 0.059630357 |
| FWER p-Value | 0.621 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PSMB1 | 2940402 | 118 | 5.165 | 0.0707 | Yes | ||
| 2 | PSMD14 | 5690593 | 291 | 4.035 | 0.1216 | Yes | ||
| 3 | PSMA4 | 4560427 | 339 | 3.803 | 0.1758 | Yes | ||
| 4 | PSMC5 | 2760315 6550021 | 469 | 3.356 | 0.2189 | Yes | ||
| 5 | PSME3 | 2810537 | 487 | 3.284 | 0.2670 | Yes | ||
| 6 | PSMA7 | 2230131 | 498 | 3.257 | 0.3150 | Yes | ||
| 7 | PSMC3 | 2480184 | 603 | 3.036 | 0.3547 | Yes | ||
| 8 | PSMD8 | 630142 | 645 | 2.912 | 0.3959 | Yes | ||
| 9 | PSMD3 | 1400647 | 849 | 2.522 | 0.4226 | Yes | ||
| 10 | PSMB3 | 4280594 | 1152 | 2.119 | 0.4380 | Yes | ||
| 11 | PSMD12 | 730044 | 1154 | 2.117 | 0.4695 | Yes | ||
| 12 | PSMB6 | 2690711 | 1234 | 2.020 | 0.4954 | Yes | ||
| 13 | CDKN1A | 4050088 6400706 | 1270 | 1.970 | 0.5229 | Yes | ||
| 14 | PSMC4 | 580050 1580025 | 1299 | 1.941 | 0.5503 | Yes | ||
| 15 | PSMC2 | 7040010 | 1411 | 1.790 | 0.5710 | Yes | ||
| 16 | MDM2 | 3450053 5080138 | 1612 | 1.571 | 0.5837 | Yes | ||
| 17 | PSMB5 | 6290242 | 1644 | 1.542 | 0.6050 | Yes | ||
| 18 | CDC25A | 3800184 | 1784 | 1.416 | 0.6186 | Yes | ||
| 19 | PSMC1 | 6350538 | 1930 | 1.286 | 0.6300 | Yes | ||
| 20 | PSMD2 | 4670706 5050364 | 1939 | 1.273 | 0.6486 | Yes | ||
| 21 | PSMC6 | 2810021 | 1957 | 1.260 | 0.6664 | Yes | ||
| 22 | PSMA2 | 6510093 | 1964 | 1.252 | 0.6848 | Yes | ||
| 23 | TP53 | 6130707 | 1986 | 1.229 | 0.7020 | Yes | ||
| 24 | PSMB10 | 630504 6510039 | 2146 | 1.098 | 0.7098 | Yes | ||
| 25 | CDK2 | 130484 2260301 4010088 5050110 | 2469 | 0.928 | 0.7063 | No | ||
| 26 | PSMA5 | 5390537 | 2641 | 0.816 | 0.7093 | No | ||
| 27 | PSMD7 | 2030619 6220594 | 3079 | 0.581 | 0.6944 | No | ||
| 28 | PSMA6 | 50609 | 5043 | 0.133 | 0.5908 | No | ||
| 29 | PSMA1 | 380059 2760195 | 8066 | 0.027 | 0.4285 | No | ||
| 30 | PSMD5 | 3940139 4570041 | 11087 | -0.020 | 0.2662 | No | ||
| 31 | ATM | 3610110 4050524 | 11988 | -0.038 | 0.2183 | No | ||
| 32 | PSMB9 | 6980471 | 14256 | -0.143 | 0.0984 | No | ||
| 33 | PSMD11 | 2340538 6510053 | 15242 | -0.337 | 0.0504 | No | ||
| 34 | PSMB4 | 520402 | 15868 | -0.602 | 0.0258 | No | ||
| 35 | PSMA3 | 5900047 7040161 | 16501 | -1.000 | 0.0067 | No | ||
| 36 | PSMD9 | 50020 5890368 | 16581 | -1.046 | 0.0180 | No | ||
| 37 | PSMD4 | 430068 | 16674 | -1.128 | 0.0299 | No | ||
| 38 | PSME1 | 450193 4480035 | 16709 | -1.157 | 0.0453 | No | ||
| 39 | PSMD10 | 520494 1170576 3830050 | 17066 | -1.530 | 0.0490 | No | ||
| 40 | PSMB2 | 940035 4210324 | 17591 | -2.307 | 0.0552 | No |
