DatasetSet_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls
#absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls
#absentNotch_versus_normalThy_repos
Phenotypephenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in classnormalThy
GeneSetREACTOME_COSTIMULATION_BY_THE_CD28_FAMILY
Enrichment Score (ES)-0.84835064
Normalized Enrichment Score (NES)-1.7369958
Nominal p-value0.0
FDR q-value0.01732169
FWER p-Value0.079
Table: GSEA Results Summary



Fig 1: Enrichment plot: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEDESCRIPTION
(from dataset)		GENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CD8087011219911.226-0.0756No
2CD863390471 620028046310.174-0.2131No
3PDCD1412008264530.063-0.3094No
4GRAP27100441 141064767040.056-0.3214No
5PTPN112230100 2470180 610052872530.043-0.3498No
6PIK3R1473067174320.039-0.3583No
7AKT1529074677930.032-0.3769No
8PAK1454031511100-0.020-0.5541No
9CTLA4659053711494-0.028-0.5746No
10PIK3CA622012912692-0.056-0.6375No
11ICOSLG7012814524-0.171-0.7316No
12FYN2100468 4760520 485068715899-0.618-0.7896No
13MAP3K8294028615987-0.666-0.7772No
14CSK635059317311-1.836-0.8013Yes
15CD281400739 421009317736-2.566-0.7582Yes
16LCK336014217786-2.667-0.6924Yes
17VAV1602048718137-3.653-0.6175Yes
18PDPK1665016818190-3.862-0.5212Yes
19CD4109001018290-4.362-0.4146Yes
20CD3D281073918306-4.485-0.3004Yes
21CD3E380005618448-5.536-0.1659Yes
22CD3G268028818554-6.8170.0033Yes
Table: GSEA details [plain text format]



Fig 2: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY: Random ES distribution   
Gene set null distribution of ES for REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY