Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | KINASE_BINDING |
| Enrichment Score (ES) | -0.501418 |
| Normalized Enrichment Score (NES) | -1.7881161 |
| Nominal p-value | 0.0017921147 |
| FDR q-value | 0.6232091 |
| FWER p-Value | 0.844 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PRDX3 | 1416292_at | 298 | 4.545 | 0.0195 | No | ||
| 2 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 361 | 4.302 | 0.0480 | No | ||
| 3 | MAP3K12 | 1417115_at 1438908_at 1456565_s_at | 732 | 3.365 | 0.0556 | No | ||
| 4 | ADAM9 | 1416094_at | 910 | 3.082 | 0.0700 | No | ||
| 5 | AKAP3 | 1421531_at 1456591_x_at | 1526 | 2.466 | 0.0599 | No | ||
| 6 | UBQLN1 | 1419385_a_at 1424368_s_at 1450345_at | 1735 | 2.308 | 0.0672 | No | ||
| 7 | CDKN2A | 1450140_a_at | 1778 | 2.279 | 0.0819 | No | ||
| 8 | TPRKB | 1424992_at 1425410_at 1425682_a_at | 2563 | 1.872 | 0.0597 | No | ||
| 9 | IRAK1 | 1448668_a_at 1460649_at | 2627 | 1.850 | 0.0703 | No | ||
| 10 | GRK5 | 1446361_at 1446998_at 1449514_at | 2835 | 1.773 | 0.0737 | No | ||
| 11 | HINT1 | 1424017_a_at 1424018_at 1457286_at | 2883 | 1.758 | 0.0844 | No | ||
| 12 | FAF1 | 1418242_at 1434370_s_at | 3164 | 1.673 | 0.0838 | No | ||
| 13 | MAPK8IP3 | 1416437_a_at 1425975_a_at 1436676_at 1460628_at | 3654 | 1.519 | 0.0725 | No | ||
| 14 | AVPR1A | 1418603_at 1418604_at | 4947 | 1.176 | 0.0220 | No | ||
| 15 | YWHAG | 1420816_at 1420817_at 1450012_x_at 1459693_x_at | 4979 | 1.167 | 0.0291 | No | ||
| 16 | CD24 | 1416034_at 1437502_x_at 1448182_a_at | 6232 | 0.937 | -0.0214 | No | ||
| 17 | IRS1 | 1423104_at | 6234 | 0.936 | -0.0146 | No | ||
| 18 | CCND3 | 1415907_at 1437584_at 1444323_at 1446567_at 1447434_at 1457549_at | 6317 | 0.920 | -0.0116 | No | ||
| 19 | AKAP12 | 1419706_a_at 1458235_at | 6483 | 0.887 | -0.0127 | No | ||
| 20 | MOBKL1A | 1430564_at 1455184_at | 6674 | 0.854 | -0.0152 | No | ||
| 21 | TRIB3 | 1426065_a_at 1456225_x_at | 6997 | 0.797 | -0.0241 | No | ||
| 22 | TOP2A | 1427724_at 1442454_at 1454694_a_at | 7292 | 0.749 | -0.0321 | No | ||
| 23 | CDKN2B | 1449152_at | 7628 | 0.694 | -0.0423 | No | ||
| 24 | AKAP5 | 1447301_at | 7675 | 0.687 | -0.0394 | No | ||
| 25 | LATS1 | 1427679_at 1460264_at | 7759 | 0.674 | -0.0383 | No | ||
| 26 | MAP3K13 | 1430137_at 1440749_at 1447699_at | 8366 | 0.575 | -0.0618 | No | ||
| 27 | APC | 1420956_at 1420957_at 1435543_at 1450056_at | 8643 | 0.529 | -0.0706 | No | ||
| 28 | AKAP11 | 1434764_at | 8939 | 0.482 | -0.0806 | No | ||
| 29 | AKAP7 | 1422143_at 1433905_at | 10277 | 0.279 | -0.1397 | No | ||
| 30 | PDLIM5 | 1429783_at 1438186_at 1442710_at 1446339_at | 10492 | 0.245 | -0.1477 | No | ||
| 31 | DLG1 | 1415691_at 1445798_at 1450768_at 1459635_at | 10669 | 0.219 | -0.1541 | No | ||
| 32 | AVPR1B | 1422204_at | 10679 | 0.217 | -0.1530 | No | ||
| 33 | IGF1R | 1426565_at 1437219_at 1443566_at 1445600_at 1445664_at 1446303_at | 10905 | 0.186 | -0.1619 | No | ||
| 34 | TOP2B | 1416731_at 1416732_at 1448458_at 1456688_at | 11030 | 0.166 | -0.1664 | No | ||
| 35 | AKAP4 | 1419019_a_at 1431868_at 1451661_at 1451662_x_at | 11178 | 0.141 | -0.1720 | No | ||
| 36 | SPDYA | 1429470_at 1432134_at 1441390_at | 11719 | 0.059 | -0.1963 | No | ||
| 37 | INSR | 1421380_at 1450225_at | 12647 | -0.098 | -0.2380 | No | ||
| 38 | ZC3HC1 | 1426654_at | 12729 | -0.109 | -0.2409 | No | ||
| 39 | KIF13B | 1433158_at 1433159_at 1436056_at 1453276_at | 13018 | -0.159 | -0.2529 | No | ||
| 40 | MAPK8IP2 | 1418785_at 1418786_at 1435045_s_at 1449225_a_at 1455194_at | 13137 | -0.179 | -0.2570 | No | ||
| 41 | PTPRR | 1426047_a_at | 13826 | -0.296 | -0.2863 | No | ||
| 42 | CDKN2C | 1416868_at 1439164_at | 14766 | -0.472 | -0.3258 | No | ||
| 43 | PTPRC | 1422124_a_at 1440165_at | 15964 | -0.730 | -0.3752 | No | ||
| 44 | BCL10 | 1418970_a_at 1418971_x_at 1418972_at 1443524_x_at | 16226 | -0.792 | -0.3814 | No | ||
| 45 | RB1 | 1417850_at 1441494_at 1444400_at 1444454_at 1457447_at | 16482 | -0.856 | -0.3868 | No | ||
| 46 | CDK5RAP2 | 1443976_at 1447103_at 1452618_at | 16602 | -0.886 | -0.3858 | No | ||
| 47 | PICK1 | 1419384_at | 17845 | -1.186 | -0.4339 | No | ||
| 48 | BCAR1 | 1439388_s_at 1450622_at | 18078 | -1.261 | -0.4354 | No | ||
| 49 | ADAM10 | 1450104_at 1460083_at | 18526 | -1.414 | -0.4455 | No | ||
| 50 | MAPK8IP1 | 1425679_a_at 1440619_at | 19069 | -1.648 | -0.4583 | No | ||
| 51 | RPS6KA4 | 1438243_at 1448498_at | 19189 | -1.699 | -0.4513 | No | ||
| 52 | FIZ1 | 1423733_a_at | 20217 | -2.429 | -0.4806 | Yes | ||
| 53 | SQSTM1 | 1440076_at 1442237_at 1444021_at 1450957_a_at | 20674 | -2.919 | -0.4801 | Yes | ||
| 54 | RELA | 1419536_a_at | 20889 | -3.265 | -0.4661 | Yes | ||
| 55 | CAMK2N1 | 1456609_at | 21326 | -4.123 | -0.4560 | Yes | ||
| 56 | LLGL1 | 1416621_at | 21333 | -4.133 | -0.4262 | Yes | ||
| 57 | CEP250 | 1421512_at | 21366 | -4.232 | -0.3968 | Yes | ||
| 58 | ITGB2 | 1450678_at | 21367 | -4.241 | -0.3659 | Yes | ||
| 59 | RAD9A | 1418404_at | 21370 | -4.242 | -0.3350 | Yes | ||
| 60 | CD4 | 1419696_at 1427779_a_at | 21452 | -4.512 | -0.3059 | Yes | ||
| 61 | LAX1 | 1438687_at | 21610 | -5.229 | -0.2749 | Yes | ||
| 62 | TRIP6 | 1449041_a_at | 21653 | -5.516 | -0.2366 | Yes | ||
| 63 | SIT1 | 1418751_at | 21824 | -7.604 | -0.1890 | Yes | ||
| 64 | SOCS1 | 1440047_at 1450446_a_at | 21837 | -8.094 | -0.1305 | Yes | ||
| 65 | CDKN2D | 1416253_at | 21858 | -8.553 | -0.0691 | Yes | ||
| 66 | MAP2K7 | 1421416_at 1425393_a_at 1425512_at 1425513_at 1440442_at 1451736_a_at 1457182_at | 21902 | -9.953 | 0.0015 | Yes |
