Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus.phenotype_ATM_minus_versus_BT_ATM_minus.cls #ATM_minus_versus_BT_ATM_minus_repos |
| Phenotype | phenotype_ATM_minus_versus_BT_ATM_minus.cls#ATM_minus_versus_BT_ATM_minus_repos |
| Upregulated in class | BT_ATM_minus |
| GeneSet | IMMUNE_SYSTEM_DEVELOPMENT |
| Enrichment Score (ES) | -0.4421388 |
| Normalized Enrichment Score (NES) | -1.6218656 |
| Nominal p-value | 0.00915751 |
| FDR q-value | 0.48919445 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | LCK | 1425396_a_at 1439145_at 1439146_s_at 1457917_at | 361 | 4.302 | 0.0197 | No | ||
| 2 | DYRK3 | 1424229_at | 458 | 4.002 | 0.0490 | No | ||
| 3 | MYH9 | 1417472_at 1420170_at 1420171_s_at 1420172_at 1440708_at | 702 | 3.417 | 0.0666 | No | ||
| 4 | LIG1 | 1416641_at | 1339 | 2.636 | 0.0597 | No | ||
| 5 | KIRREL3 | 1431402_at 1441357_at 1452728_at | 2048 | 2.102 | 0.0450 | No | ||
| 6 | PF4 | 1448995_at | 2066 | 2.093 | 0.0618 | No | ||
| 7 | HDAC9 | 1421306_a_at 1434572_at | 2624 | 1.851 | 0.0519 | No | ||
| 8 | CD79A | 1418830_at | 3085 | 1.695 | 0.0452 | No | ||
| 9 | NFAM1 | 1425714_a_at 1428790_at | 3791 | 1.482 | 0.0254 | No | ||
| 10 | CSF1 | 1425154_a_at 1425155_x_at 1448914_a_at 1460220_a_at | 4141 | 1.383 | 0.0211 | No | ||
| 11 | BLNK | 1451780_at | 4202 | 1.365 | 0.0298 | No | ||
| 12 | TGFB2 | 1423250_a_at 1438303_at 1446141_at 1450922_a_at 1450923_at | 4447 | 1.300 | 0.0296 | No | ||
| 13 | SPINK5 | 1430567_at | 5449 | 1.078 | -0.0071 | No | ||
| 14 | CDK6 | 1435338_at 1440040_at 1455287_at 1460291_at | 6050 | 0.964 | -0.0265 | No | ||
| 15 | IL10 | 1450330_at | 6230 | 0.937 | -0.0268 | No | ||
| 16 | ZBTB16 | 1419874_x_at 1427638_at 1439163_at 1445562_at 1456986_at 1459557_at | 6994 | 0.798 | -0.0550 | No | ||
| 17 | TGFB1 | 1420653_at 1445360_at | 7100 | 0.779 | -0.0532 | No | ||
| 18 | MLF1 | 1418589_a_at | 7293 | 0.749 | -0.0557 | No | ||
| 19 | SPI1 | 1418747_at | 7302 | 0.747 | -0.0498 | No | ||
| 20 | RAB3D | 1418890_a_at 1418891_a_at 1449259_at 1449260_at | 8693 | 0.522 | -0.1090 | No | ||
| 21 | INHA | 1422728_at | 8763 | 0.512 | -0.1078 | No | ||
| 22 | LRMP | 1448409_at | 9162 | 0.448 | -0.1222 | No | ||
| 23 | JAG2 | 1426430_at 1426431_at | 9543 | 0.393 | -0.1363 | No | ||
| 24 | CD40LG | 1422283_at | 9546 | 0.393 | -0.1331 | No | ||
| 25 | ACVR2A | 1437382_at 1439643_at 1445026_at 1451004_at | 9664 | 0.377 | -0.1353 | No | ||
| 26 | SOCS5 | 1423349_at 1423350_at 1441640_at 1442890_at | 9668 | 0.376 | -0.1322 | No | ||
| 27 | RPS19 | 1449243_a_at 1460442_at | 9687 | 0.373 | -0.1299 | No | ||
| 28 | INHBA | 1422053_at 1458291_at | 11897 | 0.031 | -0.2307 | No | ||
| 29 | PRL | 1429287_a_at | 12069 | 0.005 | -0.2385 | No | ||
| 30 | MAL | 1417275_at 1432558_a_at | 12813 | -0.124 | -0.2714 | No | ||
| 31 | IL7 | 1422080_at 1436861_at | 13241 | -0.197 | -0.2893 | No | ||
| 32 | TM7SF4 | 1431970_at | 13409 | -0.224 | -0.2951 | No | ||
| 33 | MAFB | 1451715_at 1451716_at | 13457 | -0.233 | -0.2952 | No | ||
| 34 | SART1 | 1448658_at | 13464 | -0.234 | -0.2936 | No | ||
| 35 | NOTCH4 | 1436901_at 1449146_at 1456263_at | 14397 | -0.398 | -0.3328 | No | ||
| 36 | RASGRP4 | 1425380_at | 14520 | -0.423 | -0.3349 | No | ||
| 37 | ACIN1 | 1416568_a_at 1421197_a_at | 14572 | -0.433 | -0.3335 | No | ||
| 38 | HDAC4 | 1436758_at 1447566_at 1454693_at | 14637 | -0.445 | -0.3327 | No | ||
| 39 | TPD52 | 1419493_a_at 1419494_a_at 1436008_at 1458668_at | 14818 | -0.483 | -0.3369 | No | ||
| 40 | TBX1 | 1425779_a_at | 14957 | -0.513 | -0.3389 | No | ||
| 41 | CARTPT | 1422825_at | 15309 | -0.585 | -0.3500 | No | ||
| 42 | LIG3 | 1423419_at 1425865_a_at 1431715_a_at 1437198_at 1453986_at | 15400 | -0.602 | -0.3491 | No | ||
| 43 | PTPRC | 1422124_a_at 1440165_at | 15964 | -0.730 | -0.3687 | No | ||
| 44 | IL4 | 1449864_at | 15987 | -0.733 | -0.3635 | No | ||
| 45 | IL12B | 1419530_at 1449497_at | 16353 | -0.826 | -0.3733 | No | ||
| 46 | CALCA | 1427355_at 1452004_at | 16545 | -0.871 | -0.3747 | No | ||
| 47 | NHEJ1 | 1425651_at 1429098_s_at | 16574 | -0.876 | -0.3686 | No | ||
| 48 | MMP9 | 1416298_at 1448291_at | 17217 | -1.023 | -0.3894 | No | ||
| 49 | IL31RA | 1445095_at 1451535_at | 17340 | -1.045 | -0.3861 | No | ||
| 50 | TNFSF13 | 1445227_at | 18530 | -1.417 | -0.4286 | No | ||
| 51 | ZAP70 | 1422701_at 1439749_at 1440178_x_at | 18827 | -1.548 | -0.4291 | Yes | ||
| 52 | MYST3 | 1436315_at 1437487_at 1446143_at 1446405_at | 18847 | -1.558 | -0.4169 | Yes | ||
| 53 | RUNX1 | 1422864_at 1422865_at 1427650_a_at 1427847_at 1440878_at 1444527_at 1446930_at 1452530_a_at 1452531_at 1452578_at 1459470_at | 18990 | -1.619 | -0.4097 | Yes | ||
| 54 | SNRK | 1425678_a_at 1448864_at | 19112 | -1.668 | -0.4012 | Yes | ||
| 55 | LDB1 | 1452024_a_at | 19436 | -1.817 | -0.4007 | Yes | ||
| 56 | CDC42 | 1415724_a_at 1435807_at 1449574_a_at 1460708_s_at | 20162 | -2.391 | -0.4138 | Yes | ||
| 57 | MAP4K2 | 1428297_at 1434833_at 1450244_a_at | 20211 | -2.423 | -0.3956 | Yes | ||
| 58 | MYST1 | 1432080_s_at | 20438 | -2.621 | -0.3839 | Yes | ||
| 59 | CEBPG | 1425261_at 1425262_at 1451639_at | 20471 | -2.660 | -0.3629 | Yes | ||
| 60 | SCIN | 1450276_a_at | 20499 | -2.694 | -0.3415 | Yes | ||
| 61 | RAG1 | 1440574_at 1450680_at | 20513 | -2.714 | -0.3192 | Yes | ||
| 62 | CD3D | 1422828_at | 20755 | -3.039 | -0.3047 | Yes | ||
| 63 | HCLS1 | 1418842_at | 20791 | -3.090 | -0.2803 | Yes | ||
| 64 | HDAC5 | 1415743_at | 20892 | -3.273 | -0.2573 | Yes | ||
| 65 | HDAC7A | 1420812_at 1420813_at | 21007 | -3.474 | -0.2333 | Yes | ||
| 66 | TAZ | 1416207_at 1453785_at | 21053 | -3.577 | -0.2053 | Yes | ||
| 67 | NOTCH2 | 1451889_at 1455556_at | 21055 | -3.584 | -0.1752 | Yes | ||
| 68 | NCOA6 | 1423374_at | 21241 | -3.923 | -0.1506 | Yes | ||
| 69 | ALAS2 | 1451675_a_at | 21365 | -4.230 | -0.1206 | Yes | ||
| 70 | ACVR1B | 1422098_at 1433725_at | 21411 | -4.378 | -0.0858 | Yes | ||
| 71 | CD4 | 1419696_at 1427779_a_at | 21452 | -4.512 | -0.0497 | Yes | ||
| 72 | ETS1 | 1422027_a_at 1422028_a_at 1426725_s_at 1452163_at | 21857 | -8.522 | 0.0035 | Yes |
