LEUCINE ISOLEUCINE AND VALINE METABOLISM%WIKIPATHWAYS_20260910%WP4686%HOMO SAPIENS	Leucine isoleucine and valine metabolism	BCKDHA	ACAD8	MCCC2	ECHS1	HIBADH	MCCC1	BCKDHB	HSD17B10	ACADSB	ACSF3	ACAT1	ALDH6A1	PCCA	AUH	IVD	PCCB	DBT	MMUT	MLYCD	BCAT1	HMGCLL1	DLD	HIBCH	BCAT2	
MAMMARY GLAND DEVELOPMENT PUBERTY STAGE 2 OF 4%WIKIPATHWAYS_20260910%WP2814%HOMO SAPIENS	Mammary gland development puberty stage 2 of 4	FOSL1	CCND1	MYC	NRIP1	ERBB2	PGR	VIM	TIMP1	STAT5A	EGF	FN1	ESR1	AREG	
OLIGODENDROCYTE SPECIFICATION AND DIFFERENTIATION LEADING TO MYELIN COMPONENTS FOR CNS%WIKIPATHWAYS_20260910%WP4304%HOMO SAPIENS	Oligodendrocyte specification and differentiation leading to myelin components for CNS	BMP4	BMP2	MAG	IL1B	PLP1	CNTF	CNP	PDGFB	ASCL1	FGF2	TNF	GLI2	SHH	SOX8	MBP	SOX9	SOX6	SOX5	NKX2-2	NKX2-6	MOG	OMG	LIF	CXCL2;CXCL3;CXCL1-1	OLIG1	IGF1	OLIG2	MYT1	SOX10	
LAMIN A PROCESSING PATHWAY%WIKIPATHWAYS_20260910%WP4299%HOMO SAPIENS	Lamin A processing pathway	ICMT	LMNA	ZMPSTE24	
NANOPARTICLE TRIGGERED REGULATED NECROSIS%WIKIPATHWAYS_20260910%WP2513%HOMO SAPIENS	Nanoparticle triggered regulated necrosis	FADD	TICAM1	TNFRSF1A	MAPK8	FTL-1	CASP8	RIPK3	PARP1	TRADD	TNF	PLA2G4A	RIPK1	
GLUTATHIONE METABOLISM%WIKIPATHWAYS_20260910%WP100%HOMO SAPIENS	Glutathione metabolism	GSTA3;GSTA5;GSTA1;GSTA2	GCLM	GGT1	GGT5	G6PD	GPX1	GPX4	IDH1	GSS	GSR	GSTT2B;GSTT2	OPLAH	GSTM1;GSTM2-1	GSTA3;GSTA1	GCLC	ANPEP	
WNT SIGNALING IN ADULT HIPPOCAMPAL NEUROGENESIS%WIKIPATHWAYS_20260910%WP5536%HOMO SAPIENS	Wnt signaling in adult hippocampal neurogenesis	CCND1	FZD1	NEUROD1	FZD3	WNT3A	WNT5A	WNT7A	PROX1	NEUROG2	WNT3	LRP6	
ARTEMISININ INHIBITION OF UVEAL MELANOMA%WIKIPATHWAYS_20260910%WP5441%HOMO SAPIENS	Artemisinin inhibition of uveal melanoma	MTOR	AKT2	AKT3	AKT1	
DOWNREGULATION OF ACE2 BY SARS COV 2 SPIKE PROTEIN%WIKIPATHWAYS_20260910%WP4799%HOMO SAPIENS	Downregulation of ACE2 by SARS CoV 2 spike protein	ACE2	ACE	AGTR1	AGTR2	
IL6 SIGNALING%WIKIPATHWAYS_20260910%WP364%HOMO SAPIENS	IL6 signaling	JAK2	IL6R	MAP3K7	JUNB	MAPK3	JAK1	NCOA1	MAP2K4	CREBBP	STAT1	BAD	PRKCD	STAT3	GAB1	PTPN11	TYK2	AGT	VAV1	NR2F6	HCK	IL6	RPS6KB1	IRF1	GRB2	VIP	IL6ST	SOS1	BCL2L1	SHC1-1	TIMP1	AKT1	CRP	GSK3B	HDAC1	PIK3R2	PIK3R1	PRDM1	NLK	SOCS3	MAP2K2;MAP2K1	MAPK1	RAC1	
POST COVID NEUROINFLAMMATION%WIKIPATHWAYS_20260910%WP5485%HOMO SAPIENS	Post COVID neuroinflammation	IL18	TMPRSS2	FURIN	IL2	IL1B	GFAP	IL4	IL1A	IFNG	HMGB1-1	TLR8	IL12A	TLR7	TLR4	TNF	TLR3	ACE2	IL6	IL10	CCL11	MAPK1	CXCL8	
OSTEOBLAST DIFFERENTIATION AND RELATED DISEASES%WIKIPATHWAYS_20260910%WP4787%HOMO SAPIENS	Osteoblast differentiation and related diseases	DLL1	DLL3	DLL4	MAPK9	WNT11	MAPK7	HES3	MAPK6	HES2	MAPK4	WNT7B	MAPK14	MAPK12	MAPK13	MAPK10	MAPK11	CTNNB1	FGF2	GLI2	SOX9	BMP4	BMP2	MAPK8	FZD1	FZD3	WNT3A	WNT5A	WNT7A	WNT3	LRP6	PIK3R2	PIK3R1	MAPK1	MAPK3	STAT1	PRKCD	IHH	FZD10	RBPJ	FGF1	FGF3	FGF4	FGF5	FGF6	FGF7	FGF8	FGF9	PRKCG	HES6	PRKCI	PRKCH	WNT5B	PRKCB	PRKCE	PRKCA	RUNX2	SMO	PRKCQ	PRKD1	NOTCH2	NOTCH3	NOTCH1	PRKDC	NOTCH4	PIK3R4	PIK3R3	PRKCZ	PIK3R6	PIK3R5	WNT6	WNT1	WNT2	WNT4	JAG2	WNT10B	SMAD1	WNT10A	SMAD4	FZD2	JAG1	FZD5	FZD4	FZD7	PTCH1	FZD6	FZD9	SMAD9	FZD8	SMAD5	FGF18	FGFR4	BMPR1B	FGFR3	FGFR2	BMPR1A	FGF10	FGFR1	WNT2B	BMPR2	PIK3CD	PIK3C2G	PIK3CB	PIK3C2A	PIK3CG	GLI3	PIK3C2B	HEY1	HEY2	WNT9B	WNT9A	WNT16	PIK3CA	MYOD1	PPARG	PIK3C3	LRP5	WNT8A	WNT8B	
MIRNA REGULATION OF DNA DAMAGE RESPONSE%WIKIPATHWAYS_20260910%WP1530%HOMO SAPIENS	miRNA regulation of DNA damage response	RB1	CDKN1A	CDKN1B	MRE11	HUS1B	BRCA1	BBC3	CASP9	PIDD1	CCND3	CCND2	CHEK2	CASP3	SESN1	CHEK1	TLK2	CCND1	TLK1	MYC	NBN	APAF1	RFC1	SMC1A	CDC25C	CDC25A	DDB2	CREB1	CCNE2	RRM2B	FANCD2	CCNE1	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	TP53	MDM2-2	CYCS-1	CCNB3	CCNB2	CCNB1	ABL1	E2F1	PMAIP1	SFN	BID	ATRIP	GADD45B	GADD45A	RPA2	PML	GADD45G	RAD52	RAD50	CDK6	RAD51	CDK5	CDK4	CDK2	CCNG1	PRKDC	CDK1	RAD17	CASP8	FAS	BAX	RAD1	ATM	ATR	RAD9A	
FOXA2 PATHWAY%WIKIPATHWAYS_20260910%WP5066%HOMO SAPIENS	FOXA2 pathway	GSTA3;GSTA5;GSTA1;GSTA2	FOXA2	ABCC3	FOXA1	SREBF1	ABCC4	ABCC2	IRS1	MTTP	IRS2	FOXO1-1	ACACA	INS;INS-IGF2	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	GSTM1;GSTM2-1	FASN	GSTA3;GSTA1	APOB	SLC27A5	PPARGC1B	
15Q13 3 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP4942%HOMO SAPIENS	15q13 3 copy number variation syndrome	MTMR10	KLF13	OTUD7A	CHRNA7;CHRFAM7A	GPR75	TRPM1	KAT2B	CREBBP	GRM6	CCL5	SERPINH1	FYN	FANCD2	FAN1	
HIPK2 IN KIDNEY FIBROSIS%WIKIPATHWAYS_20260910%WP4751%HOMO SAPIENS	HIPK2 in kidney fibrosis	SIAH1	HIPK2	
INTERACTIONS BETWEEN IMMUNE CELLS AND MICRORNAS IN TUMOR MICROENVIRONMENT%WIKIPATHWAYS_20260910%WP4559%HOMO SAPIENS	Interactions between immune cells and microRNAs in tumor microenvironment	CXCL10	TRAF6	IL2RA	IL2RB	PDCD1	STAT3	IL4	CCL5	TLR8	TLR7	TLR4	CD86	CD274	CCL13;CCL2	CD80	IL2RG	SOCS1	CTLA4	STAT6	PIAS3	TGFB2	IL4R	TGFB1	TGFB3	IRAK4	NFKB1	NFKB2	TGFBR2	
LUNG FIBROSIS%WIKIPATHWAYS_20260910%WP3624%HOMO SAPIENS	Lung fibrosis	CSF3	CSF2	SERPINA1	FAM13A	MECP2	MT2A	CYSLTR2	PLAU	IL12B	CCN2	CCR3	CCR2	DSP	EDN1	HGF	ELMOD2	IL6	SFTPC	MMP2	IL13	ATP11A	MMP9	GREM1	CCL3L1;CCL3L3;CCL3;CCL18	CALCA	EGF	CEBPB	RTEL1	CCL11	CXCL8	PARN	PDGFA	TGFA	CCL4L2;CCL4L1;CCL4	TERT	DPP9	SPP1	IL4	HMOX1	TIMP1	SKIL	STN1	CMA1	PDGFB	MUC5B	BMP7	FGF2	SMAD7	TNF	IL5	PTX3	NFE2L2	FGF1	FGF7	CXCL2;CXCL3;CXCL1-1	IGF1	IL1B	CCL5	CCL13;CCL2	TGFB1	
PROSTAGLANDIN SIGNALING%WIKIPATHWAYS_20260910%WP5088%HOMO SAPIENS	Prostaglandin signaling	CXCL10	IL1B	CCR2	IL6	MMP9	CCL3L1;CCL3L3;CCL3;CCL18	CXCL8	AREG	IL1A	IFNG	IL12A	TNF	PTGER4	CCL13;CCL2	CXCL9	PIK3CG	CSF1	PTGER2	AHR	PYCARD	CASP1	NLRP3	VEGFA	IRF7	TGFB1	CXCL2;CXCL3;CXCL1-1	CD28	IL17F	KLRD1	NFKB1	PTGES	IL17A	
PROSTAGLANDIN AND LEUKOTRIENE METABOLISM IN SENESCENCE %WIKIPATHWAYS_20260910%WP5122%HOMO SAPIENS	Prostaglandin and leukotriene metabolism in senescence	PTGER3	ALOX15	ADCY3	ALOX12	LTC4S	GNAI1	PTGS1	CYSLTR1	NRAS	ALOX5	LTA4H	PTGDS	HRAS	PTGIS	IGFBP5	PLA2G4A	ALOX15B	MAPK11	SIRT1	RB1	GNAS-1	CDKN1A	GNAQ	PRXL2B	ALOX5AP	TBXAS1	KRAS	PTGS2-2	TP53	PTGER4	PTGER2	PTGES	PTGER1	
INTRAFLAGELLAR TRANSPORT PROTEINS BINDING TO DYNEIN%WIKIPATHWAYS_20260910%WP4532%HOMO SAPIENS	Intraflagellar transport proteins binding to dynein	WDR19	IFT122	IFT80	WDR35	HSPB11	DYNC2LI1	DYNC1LI1	DYNC1LI2	IFT22	IFT43	IFT81	IFT27	DYNLRB2	DYNLRB1	IFT46	DYNC1I1	DYNC2H1	DYNC2I2	DYNC1H1	DYNC1I2	DYNC2I1	DYNLT1	IFT140	DYNLT2B	
NUCLEOSOME REMODELING COMPLEX%WIKIPATHWAYS_20260910%WP5572%HOMO SAPIENS	Nucleosome remodeling complex	H4C6	ASF1A	MCM2	ASF1B	PRKDC	NASP-1	SUPT16H	XRCC6	DAXX	PCNA	XRCC5	H4-16	NAP1L1	SSRP1	IPO4	CHAF1B	CHAF1A	RBBP4	CHEK2	HAT1	SMIM40	H4C1	
GLYCOLYSIS IN SENESCENCE%WIKIPATHWAYS_20260910%WP5049%HOMO SAPIENS	Glycolysis in senescence	RB1	LDHA	G6PD	GAPDH-1	PRKAA1	PKM	PGK1	ALDOC	ENO1	HK1	TP53	
IL4 SIGNALING%WIKIPATHWAYS_20260910%WP395%HOMO SAPIENS	IL4 signaling	JAK2	MAPK3	JAK1	STAT1	BAD	MAPK14	ATF2	STAT3	ELK1	IKBKB	PTPN11	EP300	TYK2	MAPK11	JAK3	CHUK	GAB2	FOS	DOK2	CEBPA	RPS6KB1	CBL	RELA	GRB2	INPP5D	FLNA	SOS1	SOCS5	STAT5A	STAT5B	NFKBIA	SHC1-1	CEBPB	FES	PTPN6	IL4	IRS1	IRS2	PIK3CD	AKT1	IL2RG	SOCS1	STAT6	PIK3R2	IL4R	PIK3CA	PIK3R1	SOCS3	NFKB1	MAPK1	
MARKERS OF KIDNEY CELL LINEAGE%WIKIPATHWAYS_20260910%WP5236%HOMO SAPIENS	Markers of kidney cell lineage	CITED1	EPO	TNC	SIX1	TCF21	SALL1	HNF4A	SIX2	KDR	RSPO3	RSPO1	DACT1	PDGFRB	BMP7	EMX2	FOXD1	OSR1	KCTD1	HNF1B	HNF1A	AXIN2	DCN	PAX2	ACTA2	FGF7	SFRP1	FGF8	ALDH1A2	KIT	PECAM1	TSHZ3	NTN1	NT5E	EGLN1	EGLN3	EGLN2	EYA1	BMP4	AP2B1	TBX18	PBX1	DES	NOTCH2	NPHS1	GDNF	NOTCH1	NPHS2	WT1	LHX1	TLX1	REN	FAT4	VSX2	WNT4	SMAD1	JAG1	SMAD5	WNT5A	
LIDOCAINE METABOLISM%WIKIPATHWAYS_20260910%WP2646%HOMO SAPIENS	Lidocaine metabolism	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
HOST PATHOGEN INTERACTION OF HUMAN CORONAVIRUSES MAPK SIGNALING%WIKIPATHWAYS_20260910%WP4877%HOMO SAPIENS	Host pathogen interaction of human coronaviruses MAPK signaling	MAPK9	JUNB	MAPK3	MAP2K4	MAPK8	MAPK14	ATF2	MAPK12	MAPK13	MAPK10	MAPK11	RPS6KA3	RPS6KA2	RPS6KA1	MAP3K9	FOS	MAP2K7	EIF4E	MAP3K4	MAP2K6	MAP2K3	JUN	MAP3K1	BST2	DDIT3	BCL2	IFITM3;IFITM2;IFITM1	MAP3K10	RAF1	MAP3K11	MAP2K2;MAP2K1	MAPK1	
METAPATHWAY BIOTRANSFORMATION PHASE I AND II%WIKIPATHWAYS_20260910%WP702%HOMO SAPIENS	Metapathway biotransformation Phase I and II	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	GPX4	GSS	GSR	GSTT2B;GSTT2	GSTM1;GSTM2-1	GSTA3;GSTA1	GSTA3;GSTA5;GSTA1;GSTA2	TPMT	CYP46A1	COMT	HNMT	HS6ST1	HS6ST2	HS6ST3	NAA80	NDST2	NDST1	AKR7A2	AKR7A3	NDST4	NDST3	CYP1B1	GSTK1	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	CYP39A1	SULT2B1	CYP27A1	CYP2U1	CYP2E1	SULT6B1	SULT2A1-4	NNMT	HS3ST3A1	GSTCD	MGST3	MGST1	MGST2	GLYAT	CYP4F22	CYP19A1	CYP27B1	CYP4X1	CYP2B6	CHST11	CHST12	CYP11A1	CHST10	CHST13	CHST14	GSTM4	GSTM3	EPHX2	EPHX1	CYP4F3;CYP4F2;CYP4F12;CYP4F11	CYP26A1	CYP27C1	CYP2S1	CYP1A1	NAT9	GAL3ST1	NAT10	AKR1B1	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	NAT14	HS2ST1	SULT1C3	SULT1C2	CYP26B1	AKR1B15;AKR1B10	CYP4V2	CYP2R1	UGT2A1	SULT4A1	GAL3ST3	GAL3ST4	HS3ST3B1	CHST8	CHST9	CYP2D6;LOC107987479;LOC107987478-1	CHST6	NAA30	CHST7	GSTO2	CYP2C9;CYP2C19	UGT1A1;UGT1A6	GSTO1	GPX5	AKR1A1	KCNAB1	KCNAB2	CYP7B1	KCNAB3	BAAT	INMT	NAA40-2	CYP21A2	CHST1	CHST4	NAT8L	CHST2	CHST3	CYP2J2-1	NAA20	GSTP1	AKR1D1	CYP2C18-1	CYP7A1	CYP17A1	NAA50-1	CYP2A13;CYP2A6;CYP2A7-1	CYP2F1	CYP51A1	NAT8-2	FMO1	CYP4B1	FMO2	HS3ST5	HS3ST6	FMO3	FMO4	HS3ST4	CYP8B1	FMO5	HS3ST1	SULT1B1-1	HS3ST2	GSTZ1	CYP2W1	CYP24A1	GSTA4	CYP11B1;CYP11B2	CYP20A1	
INTEGRIN MEDIATED CELL ADHESION%WIKIPATHWAYS_20260910%WP185%HOMO SAPIENS	Integrin mediated cell adhesion	ITGB3	ITGB2	ILK	ITGAE	ITGAL	MYPN	MAPK7	ITGAX	RAC3	MAPK6	ITGB8	ITGAV	MAPK4	ITGB7	ITGB6	VAV3	MAPK12	ITGA4	PDPK1	MAPK10	ITGA3	ITGA2	ITGA1	VAV2	ITGAD	ITGA8	RAPGEF1	ITGA7	ITGA6	ITGA5	ARHGEF7	CRK	DOCK1	ITGA9	ROCK1	ROCK2	SRC	CDC42	PAK1	RHO	CSK	PAK3	PAK2	PAK4	GIT2	SORBS1	CAPN11	CAPN10	ZYX	BCAR1	MAP2K6	MAP2K3	RAF1	FYN	AKT2	AKT3	AKT1	PIK3R2	MAP2K2;MAP2K1	MAPK1	RAC1	GRB2	SOS1	SHC1-1	HRAS	MYLK2	BUB1B-PAK6;PAK6	ITGA2B	ARAF	CAPN9	CAPNS1	CAPN6	CAPN7	CAPN5	CAPN2	CAPN3	CAPN1	TNS1	SELENOP	TLN1	VCL	SHC3	PXN	RAP1B	RAP1A	MAP2K5	VASP	CAV3	CAV2	CAV1	BRAF	PTK2	ITGA10	ITGA11	ITGB1	ITGAM	ITGB5	ITGB4	
CYTOKINES AND INFLAMMATORY RESPONSE%WIKIPATHWAYS_20260910%WP530%HOMO SAPIENS	Cytokines and inflammatory response	IL1B	CSF3	CSF2	IL12B	IL6	IL13	IL10	PDGFA	IL2	IL4	IL1A	IFNG	TNF	IL11	IL5	IFNB1-4	IL15	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	IL3	CSF1	CD4	IL7	HLA-DRA	TGFB1	CXCL2;CXCL3;CXCL1-1	
FELBAMATE METABOLISM%WIKIPATHWAYS_20260910%WP2816%HOMO SAPIENS	Felbamate metabolism	CYP2E1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
TRYPTOPHAN KYNURENINE PATHWAY IN POST COVID SYNDROME%WIKIPATHWAYS_20260910%WP5549%HOMO SAPIENS	Tryptophan kynurenine pathway in post COVID syndrome	IDO1	IL1B	IFNG	TNF	IFNB1-4	AHR	IL6	DDC	GOT2-1	AADAT	HAAO	KMO	TDO2	KYNU	AFMID	KYAT3	KYAT1	IDO2	
HALLMARK OF CANCER NON MUTATIONAL EPIGENETIC REPROGRAMMING%WIKIPATHWAYS_20260910%WP5483%HOMO SAPIENS	Hallmark of cancer non mutational epigenetic reprogramming	FTO	ANKRD13C	DNMT1	HDAC2	GGT6	CADM1	YTHDF3	CREBBP	DNMT3A	TET2	NOL9	PIP4K2A	EZH2	EP300	IRS1	HDAC1	IFITM3;IFITM2;IFITM1	
SOX GENES AND THEIR INFLUENCE ON NEUROGENESIS AND NEURODEVELOPMENTAL DISORDERS%WIKIPATHWAYS_20260910%WP5568%HOMO SAPIENS	SOX genes and their influence on neurogenesis and neurodevelopmental disorders	H4C6	WWTR1	YES1	SRRT	SOX11	SOX12	POU3F1	POU3F2	FGF4	UTF1	SOX2	H4-16	SOX15	ZSCAN10	TEAD2	SOX4	H4C1	
MONOAMINE TRANSPORT AND REGULATION%WIKIPATHWAYS_20260910%WP727%HOMO SAPIENS	Monoamine transport and regulation	ITGB3	IL1B	MAPK14	AGT	ACHE	TPH2	TGFB1I1	PPP2CB;PPP2CA	TNFRSF11B	DBH	SLC6A1	SLC6A2	SLC6A3	SLC6A4	HRH3	NOS1	UNC13B	CDC25C	IL1R1	TSC2	FBXO32	SYN1	SCAMP2	RBL2	TNF	SLC5A7	ADORA2A	TH	AMPH	STX1A	NECTIN2	TDO2	
PROLACTIN SIGNALING%WIKIPATHWAYS_20260910%WP2037%HOMO SAPIENS	Prolactin signaling	JAK2	SOCS2	EIF4EBP1	PTPN1	MAPK9	TEC	MAPK3	NFKBIB	JAK1	STAT1	MAPK14	STAT3	ELK1	PTPN11	VAV1	GAB2	VAV2	FOS	RPS6KB1	CBL	RELA	GRB2	FLNA	SOS1	STAT5A	STAT5B	NFKBIA	SHC1-1	CASP3	PTPN6	SRC	PAK1	MYC	ERBB2	MAPK8	HRAS	RPS6KA2	IRS1	IRS2	JUN	RAF1	FYN	PIK3CB	AKT1	PXN	MTOR	PIK3CG	PRL	NEK3	SOCS1	CTSD	GSK3B	YWHAG	PIAS3	CISH	RPS6	PIK3R2	PRLR	PIK3CA	PIK3R1	PTK2	YWHAZ	ZAP70	ITGB1	PPIB	SOCS3	PPIA	MAP2K2;MAP2K1	NFKB1	AGAP2	MAPK1	RAC1	SIRPA;SIRPB1;SIRPG	
VITAMIN B12 METABOLISM%WIKIPATHWAYS_20260910%WP1533%HOMO SAPIENS	Vitamin B12 metabolism	SCARB1	SERPINA3	MTRR	SERPINE1	PLAT	MTR-1	MPO	ICAM1	MCEE	SAA2;SAA1	CBS;CBSL	FGB	FGA	CUBN	SAA2-SAA4;SAA4	MMUT	FGG	IL6	APOA1	MAT1A	F2	RELA	F7	SHMT2	PLG	LRP2	HBD;HBB	APOE	LDLR	ABCA1	CBLIF	MMAB	INSR	MTHFR	SOD2	SOD3	SOD1	IFNG	HBA2;HBA1	TCN2	TCN1	CTH	ALB	TNF	IL1B	INS;INS-IGF2	APOB	CCL5	CCL13;CCL2	CRP	NFKB1	NFKB2	
TRANSCRIPTIONAL CASCADE REGULATING ADIPOGENESIS%WIKIPATHWAYS_20260910%WP4211%HOMO SAPIENS	Transcriptional cascade regulating adipogenesis	EGR2	CEBPD	CEBPG	GATA3	GATA2	KLF15	SREBF1	KLF2	KLF5	CEBPA	PPARG	DDIT3	CEBPB	
KYNURENINE PATHWAY AND LINKS TO CELL SENESCENCE%WIKIPATHWAYS_20260910%WP5044%HOMO SAPIENS	Kynurenine pathway and links to cell senescence	IDO1	NOS1	IFNG	TLR4	TNF	IFNB1-4	TP53	CDKN1A	KLF5	IL1R2	AHR	EIF2AK1	QPRT	AADAT	EIF2AK4	HAAO	FOXO1-1	ACMSD	KMO	CAT	TDO2	KYNU	AFMID	IDO2	
CAFFEINE AND THEOBROMINE METABOLISM%WIKIPATHWAYS_20260910%WP3633%HOMO SAPIENS	Caffeine and theobromine metabolism	CYP2A13;CYP2A6;CYP2A7-1	XDH	CYP1A2	
MITOCHONDRIAL FATTY ACID SYNTHESIS PATHWAY%WIKIPATHWAYS_20260910%WP4317%HOMO SAPIENS	Mitochondrial fatty acid synthesis pathway	ACACA	MECR	OXSM	HSD17B12	MCAT	
METABOLIC PATHWAYS OF FIBROBLASTS%WIKIPATHWAYS_20260910%WP5312%HOMO SAPIENS	Metabolic pathways of fibroblasts	SLC2A1	LPAR1	PLOD1	SLC1A5	LOXL2	LDHA	GLS	ADAMTS2	UGP2	PHGDH	PLCG1	CD36	PGM1	PSPH	SLC16A1	PYCR1	P3H4	P3H3	RHOA	GCK	GLUD1;GLUD2	UGDH	BMP1	P4HA1	P4HA2	PSAT1	P4HA3	ALDH18A1	FGFR4	SERPINH1	FGFR1	GPI	
THYROID HORMONES PRODUCTION AND PERIPHERAL DOWNSTREAM SIGNALING EFFECTS%WIKIPATHWAYS_20260910%WP4746%HOMO SAPIENS	Thyroid hormones production and peripheral downstream signaling effects	ITGB3	PFKFB2	KDM3B	NPR1	UCP1	ITPR2	ADCY8	SLC5A5	TPO	RXRA	ITGAV	NPY	PRDM16	BAD	MAP4K5	MAPK14	ATF2	PPARGC1A	DUOX2	FGF21	SLC16A10	MAFA	CTNNB1	TSHR	POMC	TG	RHEB	RPS6KB1	AGRP	SLC26A4	GRB2	PNPLA2	CASP9	SOS1	SRC	SHH	TP53	MDM2-2	ADCY3	NOTCH1	HRAS	WNT4	FOXO1-1	KLB	THRB	THRA	KDM1A	TRH	TTF2	RAF1	TTF1	MC4R	RPTOR	NPPB	PRKACA-1	RPS6KA6	NHSL1	IYD	TSC2	DUOXA2	MLST8	FGFR1	PRKG2	SLC16A2	TSHB	AKT3	ACTL6B	SECISBP2L	DIO1	MTOR	DIO3	TSC1	FRS2	SIRT6	LOC100509620;LOC112267859;AQP7	GSK3B	SLCO1C1	CREB3	RPS6	TBC1D4	MAPKAPK3	PIK3CA	ADRB3	PAX8	PPARG	AKT1S1	ZNF516	MAP2K2;MAP2K1	PLIN1	MAPK1	MGLL	
LIPID METABOLISM PATHWAY%WIKIPATHWAYS_20260910%WP3965%HOMO SAPIENS	Lipid metabolism pathway	BCKDHA	PRKAA1	PNPLA2	PRKAA2	ACSS2	ACACA	PRKAG1	PRKAG2	ABHD5	FASN	PRKAG3	PRKACB-1	LIPE	PRKAR2B	PRKAR2A	PRKAB2	PDHA1	PRKAB1	PRKACA-1	ACLY	PRKAR1B	PRKAR1A	ACSBG1	AKT2	AKT3	AKT1	PLIN1	
SYNAPTIC VESICLE PATHWAY%WIKIPATHWAYS_20260910%WP2267%HOMO SAPIENS	Synaptic vesicle pathway	SNAP25	RAB3A	CLTC	CLTA	AP2A1	PARK7	AP2A2	RIMS1	DNM1L	SLC18A1	SLC18A2	AP2M1	SLC18A3	NSF	UNC13C	SLC38A1	UNC13A	SLC32A1	SYP	SYN3	SYN2	DNM1	DNM2	DNM3	SLC25A4	AP2B1	VAMP2	NAPA	SLC22A3	STXBP1	CACNA1B	SLC1A3	CACNA1A	ATP1A2	CLN8	CPLX2	CPLX1	CPLX3	CLTCL1	AP2S1	SLC17A6	SLC17A7	SLC17A8	STX3	STX2	SYT1	SLC6A4	UNC13B	SYN1	STX1A	
TYROBP CAUSAL NETWORK IN MICROGLIA%WIKIPATHWAYS_20260910%WP3945%HOMO SAPIENS	TYROBP causal network in microglia	C3-1	ITGB2	GAPT	C1QC	ITGAX	STAT5A	IL18	GAL3ST4	SPP1	CD4	PYCARD	SLC1A5	RPS6KA1	ABCC4	GPX1	CD84	NRROS	FKBP15	NCF2	PLEK	LOXL3	TGFBR1-1	TCIRG1	LYL1	RGS1	CREB3L2	CD37	IL13RA1	RNASE6	LGALS9C;LGALS9;LGALS9B	TNFRSF1B	RUNX3	APBB1IP	SLC7A7	MAF	TYROBP	BIN2	ELF4	NPC2	DPYD	HCLS1	SFT2D2	TMEM106A	RBM47	IGSF6	KCNE3	CAPG	SAMSN1	ZFP36L2	ADAP2	HLX	CYTL1	NCKAP1L	SH2B3	ITGAM	IL10RA	PPP1R18;LOC107987457	LHFPL2	
OSX AND MIRNAS IN TOOTH DEVELOPMENT%WIKIPATHWAYS_20260910%WP3971%HOMO SAPIENS	OSX and miRNAs in tooth development	RUNX2	DMP1	KLF4	NOTCH2	DKK1	NOTCH3	DSPP	NOTCH1	ALPL	SP7	NOTCH4	SOST	BMP7	CTNNB1	HNF1A	
CHOLESTEROL BIOSYNTHESIS WITH SKELETAL DYSPLASIAS%WIKIPATHWAYS_20260910%WP4804%HOMO SAPIENS	Cholesterol biosynthesis with skeletal dysplasias	EBP	CYP51A1	NSDHL	SC5D	DHCR24	DHCR7	LBR	
QUERCETIN AND NF KB AP 1 INDUCED APOPTOSIS%WIKIPATHWAYS_20260910%WP2435%HOMO SAPIENS	Quercetin and Nf kB AP 1 induced apoptosis	NOS1	CYP2A13;CYP2A6;CYP2A7-1	IKBKB	NFE2L2	MMP1	KEAP1	ACOX2	FOS	MAFG	MAFK	PTGS2-2	VEGFA	JUN	NFKBIA	NFKB1	
BREAST CANCER PATHWAY%WIKIPATHWAYS_20260910%WP4262%HOMO SAPIENS	Breast cancer pathway	DLL1	DLL3	DLL4	WNT11	WNT7B	FGF21	CTNNB1	RB1	CDKN1A	FOS	MRE11	BRCA1	EGF	ESR1	CCND1	MYC	NBN	ERBB2	PGR	DDB2	FGF2	TP53	AXIN2	E2F1	KIT	GADD45B	GADD45A	IGF1	GADD45G	RAD50	CDK6	RAD51	CDK4	BAX	PARP1	ATM	ATR	JUN	RAF1	FZD1	FZD3	WNT3A	WNT5A	WNT7A	WNT3	LRP6	AKT2	AKT3	AKT1	MTOR	GSK3B	PIK3R2	PIK3R1	MAP2K2;MAP2K1	NFKB2	MAPK1	MAPK3	NCOA1	IGF1R	RPS6KB1	FRAT2	TNFSF11	GRB2	SKP1	CSNK2A2	SFRP4	SOS1	CSNK2B	SHC4	SHC1-1	SHC2	TCF7	DVL1	DVL2	FGF20	DVL3	FGF23	FGF22	ESR2	FGF17	FGF16	SP1	FGF19	FLT4	CETN3	PTEN	BRCA2	POLK	FZD10	APC2	NCOA3	FGF1	AXIN1	FGF3	CSNK2A1;CSNK2A3	FGF4	SOS2	FGF5	LEF1	FGF6	EGFR	FGF7	E2F2	FGF8	HES1	FGF9	E2F3	BAK1	HES5	TCF7L2	TCF7L1	WNT5B	CSNK1A1	HEYL	APC	RPS6KB2	NOTCH2	NOTCH3	NOTCH1	NRAS	NOTCH4	PIK3R3	HRAS	WNT6	WNT1	WNT2	WNT4	JAG2	WNT10B	WNT10A	KRAS	FZD2	FZD5	FZD7	FZD6	FZD9	FZD8	ARAF	FGF18	FGF10	FGFR1	WNT2B	PIK3CD	SHC3	HEY1	HEY2	BRAF	WNT16	PIK3CA	LRP5	
ONE CARBON METABOLISM%WIKIPATHWAYS_20260910%WP241%HOMO SAPIENS	One carbon metabolism	ST20-MTHFS;MTHFS	ALDH1L1	DNMT1	MTFMT	AHCYL2	AHCY	SHMT1	MTRR	GLRX	MAT2B	DNMT3A	TYMS	MTR-1	FTCD	ATIC	MTHFD1L	DNMT3B	AMT	DHFR2;DHFR	BHMT	FOLH1B;FOLH1	MTHFD1	MTHFD2	CHDH	GART	MAT1A	SHMT2	MTHFR	TCN2	
INFLAMMATORY BOWEL DISEASE SIGNALING%WIKIPATHWAYS_20260910%WP5198%HOMO SAPIENS	Inflammatory bowel disease signaling	STAT1	STAT3	IL6	IL21	IL22	IL13	IL23R	RORC	JUN	RORA	NOD2	HLA-DMA	IL18RAP	IL10	TBX21	STAT4	SMAD2;SMAD3	IL18	IL21R	IL12RB1	IL12RB2	IL2	IFNGR1	NFATC1	IL4	FOXP3	IL1A	IFNG	IL23A	TLR5	MAF	TLR2	IL12A	TLR4	TNF	IL5	GATA3	IL2RG	STAT6	IL4R	TGFB1	IL17F	NFKB1	
DNA DAMAGE RESPONSE ONLY ATM DEPENDENT %WIKIPATHWAYS_20260910%WP710%HOMO SAPIENS	DNA damage response only ATM dependent	MAPK9	WNT11	RAC3	WNT7B	MAPK10	CTNNB1	CDKN1A	CDKN1B	BBC3	CCND3	CCND2	FOSL1	CDC42	CCND1	MYC	ERBB2	TP53	MDM2-2	ABL1	PMAIP1	MAPK8	BAX	ATM	IRS1	MAP3K4	JUN	MAP3K1	BCL2	WNT3A	WNT5A	WNT7A	WNT3	RBL2	AKT2	AKT3	AKT1	GSK3B	PIK3R2	PIK3R1	TGFB1	NFKB1	NFKB2	MAPK1	RAC1	MAP3K7	BAD	PLAU	GRB2	SOS1	SHC1-1	TCF7	LDLR	DVL1	DVL2	DVL3	INSR	HMGB1-1	PTEN	AXIN1	SOS2	LEF1	CAT	BAK1	TCF7L2	TCF7L1	WNT5B	APC	NRAS	PIK3R4	PIK3R3	HRAS	PIK3R5	WNT6	WNT1	WNT2	RHOA	WNT4	WNT10B	WNT10A	KRAS	SMAD4	SMAD2;SMAD3	SCP2	PDK1	WNT2B	FOXO3	BCL2L11	PIK3CD	PCK2	PIK3C2G	MLKL	PIK3CB	G6PC1	PIK3C2A	BCL6	PIK3CG	TP73	FASLG	PIK3C2B	PPP2R5E	PPP2R5C	BIK	CDKN2A	WNT16	CCNG2	PIK3CA	PIK3C3	
GROWTH FACTORS AND HORMONES IN BETA CELL PROLIFERATION%WIKIPATHWAYS_20260910%WP5385%HOMO SAPIENS	Growth factors and hormones in beta cell proliferation	MAPK3	CDK4	CDK2	IGF1R	KRAS	FOXO1-1	INS;INS-IGF2	TGFBR1-1	PDGFA	MYC	INSR	SMAD7	AKT2	AKT3	AKT1	BRAF	CRTC2	FLT1	FOXM1	RASSF1	IGF1	PDX1	MAPK1	PGF	DLK1	
EICOSANOID METABOLISM VIA CYCLOOXYGENASES COX %WIKIPATHWAYS_20260910%WP4719%HOMO SAPIENS	Eicosanoid metabolism via cyclooxygenases COX	PTGFR	HPGD	PTGDR2	EHHADH-1	PLA2G5	PLA2G6	PTGS1	TBXA2R	JMJD7-PLA2G4B;PLA2G4B	PTGR1-1	PTGDR	PTGIR	PTGDS	ACAA1-1	PTGR2	PTGIS	ACOX1	PLA2G4A	ACOX3	PPARD	CYP4F3;CYP4F2;CYP4F12;CYP4F11	ACOX2	PRXL2B	TBXAS1	PTGS2-2	AKR1B1	PPARG	PTGES	
MITOCHONDRIAL COMPLEX III ASSEMBLY%WIKIPATHWAYS_20260910%WP4921%HOMO SAPIENS	Mitochondrial complex III assembly	UQCRB	UQCC3	UQCC2	UQCC1	UQCR11	UQCR10	BCS1L	TTC19	UQCRQ	LYRM7	UQCRC1	UQCRFS1	CYC1	UQCRC2	
METASTATIC BRAIN TUMOR%WIKIPATHWAYS_20260910%WP2249%HOMO SAPIENS	Metastatic brain tumor	CDC42	CDK6	MYC	E2F3	PIK3R1	TP53	
KREBS CYCLE DISORDERS%WIKIPATHWAYS_20260910%WP4236%HOMO SAPIENS	Krebs cycle disorders	DLST	GPT	DHTKD1	LDHB	LDHA;LDHC	LDHA	SUCLA2	MPC1	SUCLG2	SUCLG1	PCK2	PDHX	FH	
MULTIPLE EPIPHYSEAL DYSPLASIA AND PSEUDOACHONDROPLASIA GENES%WIKIPATHWAYS_20260910%WP4789%HOMO SAPIENS	Multiple epiphyseal dysplasia and pseudoachondroplasia genes	COMP	COL9A1	MATN1	COL9A3	COL9A2	MATN3	
GENES AND COMPLEXES INVOLVED IN THE DNA REPAIR PATHWAYS%WIKIPATHWAYS_20260910%WP4946%HOMO SAPIENS	Genes and complexes involved in the DNA repair pathways	MRE11	BRCA1	CHEK1	NBN	RFC1	DDB2	FANCD2	DCLRE1C	CCNH	MPG	FAAP100	LIG1	REV1	LIG4	LIG3	RBX1	MSH6	NEIL3	NEIL2	MSH2	MSH3	CENPS-CORT;CORT;CENPS	RPA2	XPA	XPC	BRIP1	RAD52	NTHL1	RAD50	NHEJ1	FANCI	RAD51	FANCM	XRCC4	FANCL	FANCA	XRCC1	FANCC	FANCE	PALB2	FANCG	PARP1	FANCF	ATM	CDK7	ATR	MNAT1	FEN1	WDR48	OGG1	CETN2	POLB	EXO1	REV3L	POLI	POLL	POLE	POLH	RFC5	RFC3	RFC4	RFC2	PARP2	RAD23A	ERCC5;BIVM-ERCC5	TERF2	RAD23B	DDB1	RAD51C	GTF2H2C;GTF2H2C_2;GTF2H2	PNKP	FAAP24	UNG	RAD54B	POLD3	FAN1	POLD4	WRN	LOC105377022;FANCB	TDG	POLD1	POLD2	USP1	PMS2	MUTYH	MBD4	CENPX	MGMT	POLM	RPA1	APEX2	GTF2H1	GTF2H3	MLH1	GTF2H4	POLE4	SMUG1	CUL4A	ERCC3	ERCC4	POLE2	RPA3	APEX1	ERCC1	POLE3	ERCC2	ERCC8	ERCC6	CUL4B	HMGB1-1	BRCA2	POLK	PRKDC	RAP1A	XRCC6	PCNA	XRCC5	
SOMATIC SEX DETERMINATION%WIKIPATHWAYS_20260910%WP4814%HOMO SAPIENS	Somatic sex determination	WT1	RSPO1	PTGDS	DMRT1	DHH	GATA4	FOXL2	CTNNB1	SOX8	NR5A1	SRY	SOX9	WNT4	AMH	ZFPM2	FGF9	
G1 TO S CELL CYCLE CONTROL%WIKIPATHWAYS_20260910%WP45%HOMO SAPIENS	G1 to S cell cycle control	MCM2	POLE2	RPA3	RB1	CDKN1A	CDKN1B	CDKN1C	MCM7	CREB3L3	CREB3L4	CREB3L1	CCND3	CCNA1	CCND2	TFDP1	TFDP2	MCM3	MCM4	MCM5	MCM6	CCND1	PRIM2	MYC	ATF6B	PRIM1	ORC5	ORC4	CDC45	CDC25A	ORC6	ORC1	CREB1	ORC3	CCNE2	ORC2	CDKN2D	CDKN2B	CCNE1	CDKN2C	WEE1	TP53	POLA2	CCNH	MDM2-2	CCNB1	E2F1	E2F2	E2F3	GADD45A	RPA2	MYT1	CDK6	CDK4	CDK2	CDK1	ATM	CDK7	MNAT1	POLE	PCNA	CREB3	CDKN2A	CCNG2	RPA1	
13Q12 OR CRYL1 COPY NUMBER VARIATION %WIKIPATHWAYS_20260910%WP5405%HOMO SAPIENS	13q12 or CRYL1 copy number variation	CRYL1	
3Q29 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP4906%HOMO SAPIENS	3q29 copy number variation syndrome	STAT5A	STAT5B	MYC	PAK2	TFRC	CEP19	HFE	SLC40A1	PIGZ	CASP7	SENP5	H2BC21	UBXN7	MAD2L1BP-1	SMCO1	PCYT1A	NCBP1	FBXW7	ADAM10	SLC51A	SLC51B	FNDC8	PIGM	GRIA1	MYCBP2	RNF168-1	RNF8	FBXO45	HIF1A	BRINP1	PIK3R3	TM4SF19	CEP350	MCRS1	PIGX-1	WDR53	SIRT1	ZNF76	RABL2A;RABL2B	NCBP2-1	TF	DLG1	UBE2N	MELTF	NRROS	NF2	DYNC2H1	HAMP	DYNC2I2	JUN	CEP43	DYNC2I1	DYNLT1	DYNLT2B	DYNC2LI1	DYNLRB2	DYNLRB1	PXN	TGFB1	
MET IN TYPE 1 PAPILLARY RENAL CELL CARCINOMA%WIKIPATHWAYS_20260910%WP4205%HOMO SAPIENS	MET in type 1 papillary renal cell carcinoma	MAPK3	BAD	STAT3	GAB1	PTPN11	JAK3	CDKN1A	HGF	RAPGEF1	CBL	GRB2	SOS1	CRK	SRC	CDC42	PAK1	PAK3	PAK2	PAK4	KDR	SOS2	VEGFA	NRAS	MAPK8	PLCG1	PIK3R3	HRAS	KRAS	JUN	ALK	ETS1	CRKL	ELOA	INSL3	TFE3	BUB1B-PAK6;PAK6	RAF1	MET	PRCC	ARAF	RPL11	PAK5	C8orf34	STRN	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	RAP1B	RAP1A	PIK3R2	BRAF	PIK3CA	PIK3R1	PTK2	MAP2K2;MAP2K1	MAPK1	RAC1	
SEBALEIC ACID FORMATION AND METABOLISM%WIKIPATHWAYS_20260910%WP5315%HOMO SAPIENS	Sebaleic acid formation and metabolism	CYP4F3;CYP4F2;CYP4F12;CYP4F11	FADS2	ACSL1	FADS1	ALOX5	
TGF BETA RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP560%HOMO SAPIENS	TGF beta receptor signaling	MAPK9	MAPK3	JAK1	SERPINE1	CREBBP	STAT1	ITGB6	STAT3	EP300	CTNNB1	FOS	EGF	SPP1	IFNG	SKIL	SMAD7	TNF	LEF1	LIF	BMP4	RUNX2	HRAS	WNT1	SMAD1	SMAD4	JUN	TGFBR1-1	TFE3	SMAD2;SMAD3	SMAD9	SMAD5	RUNX3	ZFYVE9	TGIF1-1	FST	LEFTY2;LEFTY1	NOG	FOXH1	TGFBR3	ZEB2	ENG	LTBP1	THBS1	ZNF423	INHBA	SMAD6	FKBP1A	SKI	BAMBI	TGFB1	NFKB1	TGFBR2	
FAMILIAL HYPERLIPIDEMIA TYPE 1%WIKIPATHWAYS_20260910%WP5108%HOMO SAPIENS	Familial hyperlipidemia type 1	APOA4	APOA5	LMF1	LIPC	APOC2	ANGPTL8	ANGPTL3	ANGPTL4	PLTP	GPIHBP1	APOA1	CETP	LRP1	SEL1L	APOA2	LPL	LDLR	LCAT	
NUCLEOTIDE METABOLISM%WIKIPATHWAYS_20260910%WP404%HOMO SAPIENS	Nucleotide metabolism	PRPS2	PRPS1	RRM2B	RRM1	ADSL	NME2	OAZ1	DHFR2;DHFR	SAT1	POLD1	SRM	POLA1	IMPDH1	MTHFD2	POLB	HPRT1	ADSS2	RRM2-1	POLG	
ALZHEIMER 39 S DISEASE AND MIRNA EFFECTS%WIKIPATHWAYS_20260910%WP2059%HOMO SAPIENS	Alzheimer 39 s disease and miRNA effects	ITPR2	GAPDH-1	HSD17B10	IKBKB	CHUK	RELA	APP	CALML6	CALML3	CALML4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD2	PSMD3	PSMD1	ATG14	PSMC2-1	ATG13	DKK2	DKK4	VDAC3	ULK2	ULK1	VDAC1	ATF6	TNF	ATF4	APH1A	NCSTN	GRIN2A	PPP3R1	AXIN2	APH1B	NRBF2	XBP1	EIF2AK3	EIF2AK2	GRIN2C	GRIN2B	GRIN2D	ATG2A	NOX4	CALM1	CALM2	NOX1	ATG2B	IDE	SLC25A4	RYR3	TUBA1C	IL1B	PPP3CA	PPP3CB	TUBA1A	PPP3CC	PSENEN	MAPK8	MME	BACE1	CASP8	PSMA5	PSMA6	PLCB3	PSMA3	PLCB4	FADD	PSMA4	PSMA1	MAPT	TNFRSF1A	PLCB1	PLCB2	MAP2K7	TUBB3;TUBB6	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	DDIT3	PSMB2	PSMB3	PSMB1	APBB1	TUBB4B	RAF1	CALM3;CALM1	GRIN1	FZD1	PSMA2-1	PSMC5	FZD3	PSMC6	PSMC3	WNT3A	PSMC4	WNT5A	WNT7A	PSMC1	CDK5R1	IRS4	VDAC2-1	WNT3	KIF5C	LRP6	AKT2	KIF5B	AKT3	KIF5A	AKT1	TUBB1	MAP3K5	MTOR	CYBB	TUBA4A	ERN1	ADAM17	PPIF	PPID	GSK3B	RTN3	PIK3R2	PSMD12	PIK3R1	PSMD14	PSMD13	PSEN2	ITPR1	MAP2K2;MAP2K1	CACNA1D	GPR83	MAPK1	ITPR3	CACNA1C	PSEN1	CACNA1F	KLC1	AGER	MAPK3	DKK1	RTN4	KLC4	KLC3	KLC2	ATG101	NAE1	BAD	CACNA1S	TUBA3E;TUBA3C-1	EIF2S1	SEM1	TUBB4A;TUBB;TUBB8B;TUBB8	TPTEP2-CSNK1E;CSNK1E	MCU	TUBA8	ATP2A3	IL6	ATP2A2	ATP2A1	FRAT2	RB1CC1	TUBB2B;TUBB2A	TRAF2	CSNK2A2	WIPI1	SFRP4	WIPI2	CSNK2B	SLC25A5	SLC25A6	BECN1	TUBAL3	DVL1	BECN2	DVL2	AMBRA1	SNCA	DVL3	NOS2	ADRM1	SLC25A31	IL1A	FZD10	APC2	AXIN1	CSNK2A1;CSNK2A3	CSNK1A1	WNT5B	APC	PIK3R4	PIK3R3	WNT6	WNT1	WNT2	WNT4	WNT10B	WNT10A	FZD2	FZD5	FZD7	FZD6	FZD9	FZD8	ARAF	CAPN2	CAPN1	WNT2B	PIK3CD	PIK3CB	BRAF	WNT16	PIK3CA	PIK3C3	LRP5	MAPK9	WNT11	WNT7B	MAPK10	CTNNB1	CASP9	CASP3	APAF1	CYCS-1	BID	CDK5	FAS	IRS1	IRS2	INS;INS-IGF2	CHRNA7;CHRFAM7A	NOS1	NFKB1	APOE	INSR	CSF1	CASP7	ADAM10	NRAS	HRAS	GNAQ	KRAS	PTGS2-2	LRP1	LPL	
VITAMIN D RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2877%HOMO SAPIENS	Vitamin D receptor pathway	IL1RL1	CLMN	CREG2	HSD17B2	LRRC8A	LRRC25	S100G	CDX2	RXRA	KRT13	G0S2	MYO9B	ATP2B1	DEFB132	CASP5;CASP4	KRTAP10-10;KRTAP10-2;KRTAP10-3;KRTAP10-11;KRTAP10-9-2	PPARD	CD9	CEACAM8;CEACAM7;CEACAM6;CEACAM1;CEACAM5-1	DEFB4A;DEFB4B	CDKN1A	CDKN1B	CEBPA	CCND1	MYC	NRIP1	CCNE1	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	HNF1A	SFRP1	GADD45A	NOX1	CDK2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	G6PD	FOXO1-1	TNFRSF11B	LGALS9C;LGALS9;LGALS9B	CTLA4	TGFB2	SULT2A1-4	PRDM1	TGFB1	JUNB	CYP27B1	KLF4	CYP2B6	CBS;CBSL	CYP2S1	CYP1A1	TNFSF11	SULT1C2	FGF23	STEAP4	SPP1	LPGAT1	GXYLT2	CLDN2	SLC8A1	CYP2D6;LOC107987479;LOC107987478-1	KRTAP10-1;KRTAP10-12;KRTAP10-7;KRTAP10-6;KRTAP10-4	IL12A	STS	CDKN2D	SALL4	CDKN2B	SPRR1A;SPRR1B	CDKN2C	KRT16;KRT14	CYP2C9;CYP2C19	EPHB4	KRT71	PTGER4	IGFBP1	SLC34A2	S100A2	IGFBP3	TPM1	MED9	CDKAL1	CDC34	NINJ1	S100A6	S100A4	S100A9	S100A8	ABCB1	COL13A1	CLEC16A	ADRB2	EFNA5	PRKCQ	RASGRP1	KNG1	KLK6	CYP7A1	CCNC-1	CRACR2A	CRACR2B	HIF1A	DND1	ALOX5	BTLA	CD14	KL	SLC37A2	IGFBP5	VDR	KRTAP8-1	NFATC2	STAM	BMP6	TRPV6	TNFSF4	TRPV5	ID1	PNOC	ID4	IGSF9B	CLPTM1L	MXD1	CYP24A1	CD200	CD40	IL25	TNFAIP3	SLC2A4	ADRA1B	TREM1	ORM2;ORM1	THBD	ADAMTS5	CASP14	DUSP10	ADGRE5	DNER	DACT2	TIMP2	TIMP3	SOSTDC1	BDKRB1	CA9	ABCD1	BCL6	CAMP	SERPINB1	IRF4	IRF8	IRF5	COLEC11	SATB1	CDKN2A	PTH	SEMA3B	ASAP2	ATP2C2	TRAK1	ITGAM	LRP5	ALPG;ALPP;ALPI-1	CST6	PTHLH	
CELL CYCLE%WIKIPATHWAYS_20260910%WP179%HOMO SAPIENS	Cell cycle	MCM2	EP300	RB1	SMC3	CDKN1A	CDC14A	CDKN1B	CDC14B	CDC20	CDC23	CDC27	SKP2	ANAPC7	CCND3	CDC25B	CCND2	ANAPC4	CHEK2	ANAPC5	MAD1L1	ANAPC1	CHEK1	ANAPC2	E2F4-1	CCND1	ANAPC13	MYC	CUL1	PKMYT1	ANAPC10	ANAPC11	SMC1A	CDC25C	RAD21	CDC25A	ZBTB17	PLK1	CDC7	CCNE2	CDC6	STAG1	STAG2	CCNE1	CDC16	YWHAE	TP53	YWHAB	CCNH	MDM2-2	YWHAQ	PTTG1;PTTG2	CCNB3	CCNA2-1	CCNB2	YWHAH	CCNB1	SMC1B	ABL1	RBL1	DBF4	E2F1	RBX1	ESPL1	SFN	TTK	FZR1	BUB3	GADD45B	E2F5	GADD45A	BUB1	MAD2L2	WEE2	GADD45G	CDK6	HDAC2	CDK4	CDK2	CDK1	ATM	CDK7	ATR	RBL2	GSK3B	YWHAG	HDAC1	TGFB2	TGFB1	YWHAZ	TGFB3	CDKN1C	MCM7	SKP1	CCNA1	TFDP1	TFDP2	MCM3	MCM4	MCM5	MCM6	ORC5	ORC4	CDC45	ORC6	ORC1	ORC3	ORC2	CDKN2D	CDKN2B	CDKN2C	WEE1	E2F2	E2F3	PRKDC	SMAD4	SMAD2;SMAD3	PCNA	CDKN2A	
SEROTONIN RECEPTOR 2 AND ELK SRF GATA4 SIGNALING%WIKIPATHWAYS_20260910%WP732%HOMO SAPIENS	Serotonin receptor 2 and ELK SRF GATA4 signaling	RASGRF1	RAF1	HTR2B	HTR2A	RASGRP1	ELK4	MAPKAPK2	MAPK3	NRAS	HRAS	ELK1	GATA4	GNAQ	KRAS	ITPR1	MAP2K2;MAP2K1	MAPK1	SRF	
VITAMIN D SENSITIVE CALCIUM SIGNALING IN DEPRESSION%WIKIPATHWAYS_20260910%WP4698%HOMO SAPIENS	Vitamin D sensitive calcium signaling in depression	CACNA1C	CYP27B1	ITPR2	TPH1	KDM3A	CHRM1	KDM1B	RXRA	GRM5	CALB1	KDM6B	ATP2B1	ATP2B4	ATP2B3	VDR	ATP2B2	KCNQ2	KCNQ3	PVALB	G6PD	GSR	TPH2	BCL2	KDM1A	GCLC	GGT1	GRIN1	SLC8A1	NFE2L2	GRIN2A	CYP27A1	GRIN2C	GRIN2B	GRIN2D	ITPR1	ITPR3	
FATTY ACID OMEGA OXIDATION%WIKIPATHWAYS_20260910%WP206%HOMO SAPIENS	Fatty acid omega oxidation	ADH4	ADH1C;ADH1B;ADH1A	ALDH2	CYP1A1	ALDH1A1	CYP2E1	CYP2A13;CYP2A6;CYP2A7-1	CYP2D6;LOC107987479;LOC107987478-1	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
BLOOD BASED NEUROINFLAMMATION MARKERS %WIKIPATHWAYS_20260910%WP5548%HOMO SAPIENS	Blood based neuroinflammation markers	TAC1	TREM1	IL1B	GFAP	CCL5	TNF	CCL13;CCL2	IL6	CRP	GRN	BDNF	ADM	TREM2	CX3CL1	CCL23;CCL15	TSPO	NEFL	CCL11	OLR1	CHI3L1	
ENDOMETRIAL CANCER%WIKIPATHWAYS_20260910%WP4155%HOMO SAPIENS	Endometrial cancer	ILK	MAPK3	BAD	ELK1	PDPK1	CTNNB1	CDKN1A	FOS	GRB2	CASP9	SOS1	EGF	TCF7	CCND1	MYC	ERBB2	DDB2	PTEN	FGF2	POLK	APC2	TP53	FGF1	AXIN1	AXIN2	SOS2	LEF1	EGFR	BAK1	TCF7L2	GADD45B	TCF7L1	GADD45A	GADD45G	APC	NRAS	PIK3R3	BAX	HRAS	KRAS	RAF1	CDH1	ARAF	CTNNA1	CTNNA3	CTNNA2	FGFR3	FGFR2	FGFR1	FOXO3	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	GSK3B	PIK3R2	BRAF	PIK3CA	PIK3R1	MAP2K2;MAP2K1	MAPK1	
INTERFERON SIGNALING IN TUBERCULOSIS%WIKIPATHWAYS_20260910%WP4197%HOMO SAPIENS	Interferon signaling in tuberculosis	JAK2	IFNGR1	IFNAR2	JAK1	STAT2	IFNGR2	IFNG	TAP1	STAT1	IFI35	IFIT1	PSMB8	IFIT3	PIAS1	MX1-1	TYK2	OAS1	IRF9	PTPN2	IFNAR1	SOCS1	IRF1	IFITM3;IFITM2;IFITM1	
PHOSPHOINOSITIDES METABOLISM%WIKIPATHWAYS_20260910%WP4971%HOMO SAPIENS	Phosphoinositides metabolism	MTMR2	MTMR3	MTMR8	MTMR9	MTMR4	MTMR6	MTMR7	MTM1	PLCG2	PIP5K1A	PIP5K1B	PIP5K1C	PIKFYVE	PLCH1	PLCH2	PLCD3	PLCD4	PLCD1	INPP5D	PTEN	PLCG1	PIK3R4	PIP4K2A	PLCB3	PLCB4	PLCB1	PLCB2	MTMR10	PIK3CD	PIK3C2G	PIK3CB	PIK3C2A	PIK3CG	MTMR12	PIK3C2B	MTMR11	PIP4P2	PIP4P1	PLCZ1	PLCE1	PIP4K2B	PIK3CA	PIP4K2C	SBF1	SBF2	PIK3C3	SACM1L	OCRL	MTMR1	
TGF BETA SIGNALING IN THYROID CELLS FOR EPITHELIAL MESENCHYMAL TRANSITION%WIKIPATHWAYS_20260910%WP3859%HOMO SAPIENS	TGF beta signaling in thyroid cells for epithelial mesenchymal transition	SMAD2;SMAD3	TNC	RUNX2	CDH1	MAPK3	VIM	AKT2	AKT3	AKT1	CDH6	CDH2	SNAI1	SNAI2	ID1	CDH16	SMAD4	FN1	MAPK1	
DISORDERS OF MITOCHONDRIAL HOMEOSTATIS DYNAMICS PROTEIN IMPORT AND QUALITY CONTROL%WIKIPATHWAYS_20260910%WP5504%HOMO SAPIENS	Disorders of mitochondrial homeostatis dynamics protein import and quality control	MIPEP	UBXN1	CLPB	MICOS13	TXN2	AIFM1	OPA1	OPA3	C1QBP	GDAP1L1	SACS	LONP1	UFD1	PMPCB	PMPCA	UBXN6	SLC25A46	OXA1L	AFG3L2	PPA2	CLPP	YME1L1	MICU1	PRKN	HTRA2	SPG7	DNM1L	MFF	HSPD1	TIMM50	MSTO1	PITRM1	ATAD3A;ATAD3B	MFN1	MFN2	MARCHF5-1	MCL1	HSPA9	DNAJC19	TIMM8A	TIMMDC1	USP9X	TXNRD2	AGK	TMEM126A-1	PYCR2	PYCR3	GFER	COQ5	COQ3	PINK1	NPLOC4	XPNPEP3	SFXN4	RTN4IP1	VCP-1	PYCR1	PLEK	STAT2	TRAK1	
GLYCOSYLPHOSPHATIDYL INOSITOL ANCHOR PATHWAY%WIKIPATHWAYS_20260910%WP5505%HOMO SAPIENS	Glycosylphosphatidyl inositol anchor pathway	PIGM	PIGS	PIGX-1	PIGU	PIGT	PGAP1	PIGO	PGAP2	PIGN	GPAA1	PGAP3	PIGQ	PIGP	PIGW	PIGV	PIGC	DPM2	PIGB	PIGA	PIGK	MPPE1	PIGL	PIGG	PIGF	PIGH	
INTERACTIONS BETWEEN LOXL4 AND OXIDATIVE STRESS PATHWAY%WIKIPATHWAYS_20260910%WP3670%HOMO SAPIENS	Interactions between LOXL4 and oxidative stress pathway	BMP2	DDR1	NQO1	SUV39H1	ANXA5	LOXL4	NRF1	ECSIT	PKD1	COL2A1	CDC37	EXOC6	NFE2L2	SIRT1	IGFBP7	FGF7	TGFB1	FN1	
TGF 1 SMAD2 3 SIGNALLING IN DECIDUAL NK CELLS AT THE FETAL MATERNAL INTERFACE%WIKIPATHWAYS_20260910%WP5637%HOMO SAPIENS	TGF 1 SMAD2 3 signalling in decidual NK cells at the fetal maternal interface	CXCL10	SMAD2;SMAD3	IL2RA	ITGAE	FOXP3	IFNG	CD14	SMAD7	CD9	ANGPT2	ITGA1	ANGPT1	CD4	SMURF2	VEGFC	FCGR3A;FCGR3B	KLRC4-KLRK1;KLRK1	SMAD4	NCAM1	TGFB1	TGFBR1-1	PGF	CXCL8	TGFBR2	
UREA CYCLE AND METABOLISM OF AMINO GROUPS%WIKIPATHWAYS_20260910%WP497%HOMO SAPIENS	Urea cycle and metabolism of amino groups	GATM	CPS1	SMS	SARDH	PYCR3	ASL	NAGS	CKB	OTC	PYCR1	SRM	GLUD1;GLUD2	GAMT	ARG2	ACY1;ABHD14A-ACY1	ALDH18A1	OAT	CKM	ARG1	ODC1	ASS1	
FOLATE METABOLISM%WIKIPATHWAYS_20260910%WP176%HOMO SAPIENS	Folate metabolism	SCARB1	SERPINA3	MTRR	SLC46A1	SERPINE1	PLAT	FLAD1	MTR-1	RFK	MPO	GPX6	ICAM1	IZUMO1R	SLC19A1	SAA2;SAA1	FOLR2	CBS;CBSL	FOLR1	FGB	FGA	SAA2-SAA4;SAA4	FGG	IL6	APOA1	MAT1A	F2	RELA	F7	SHMT2	PLG	HBD;HBB	LDLR	ABCA1	INSR	MTHFR	IL2	SOD2	SOD3	IL4	SOD1	IFNG	HBA2;HBA1	CTH	ALB	TNF	TP53	CSF1	CAT	ST20-MTHFS;MTHFS	IL1B	AHCY	SHMT1	DHFR2;DHFR	MTHFD1	MTHFD2	GPX1	GART	GPX4	INS;INS-IGF2	APOB	CCL13;CCL2	CRP	NFKB1	NFKB2	
NSP1 FROM SARS COV 2 INHIBITS TRANSLATION INITIATION IN THE HOST CELL%WIKIPATHWAYS_20260910%WP5027%HOMO SAPIENS	nsp1 from SARS CoV 2 inhibits translation initiation in the host cell	EIF2S1	EIF2S2	EIF2S3;EIF2S3B	EIF1	EIF3C;EIF3CL	EIF5	EIF3I	EIF1AY;EIF1AX	EIF3J	EIF3G	EIF3H	EIF3E	EIF3F	EIF3D	EIF3A	EIF3B	
TYROSINE METABOLISM AND RELATED DISORDERS%WIKIPATHWAYS_20260910%WP4506%HOMO SAPIENS	Tyrosine metabolism and related disorders	TAT	FAH	HPD	GSTZ1	HGD	
PLATELET MEDIATED INTERACTIONS WITH VASCULAR AND CIRCULATING CELLS%WIKIPATHWAYS_20260910%WP4462%HOMO SAPIENS	Platelet mediated interactions with vascular and circulating cells	SELPLG	IL1B	VCAM1	PF4;PF4V1-1	SELE	SELP	CD40LG	CCL5	TLR2	TLR7	ICAM1	TLR4	CCL13;CCL2	TGFB2	TGFB1	TGFB3	CD40	
SEROTONIN HTR1 GROUP AND FOS PATHWAY%WIKIPATHWAYS_20260910%WP722%HOMO SAPIENS	Serotonin HTR1 group and FOS pathway	RASGRF1	JAK2	HTR2A	RASGRP1	ELK4	MAPK3	MAPKAPK2	GNAI1	MAPK14	STAT3	ELK1	PDPK1	RHOA	GNAQ	FOS	MAP2K6	MAP2K3	MAP3K1	GNAI3	CREB1	GNAI2	RPS6KA5	HTR1E	HTR1F	HTR1D	HTR1A	HTR1B	GNAO1	RAP1A	BRAF	MAPKAPK3	PIK3CA	ITPR1	MAP2K2;MAP2K1	MAPK1	SRF	
INTERLEUKIN 1 IL 1 STRUCTURAL PATHWAY%WIKIPATHWAYS_20260910%WP2637%HOMO SAPIENS	Interleukin 1 IL 1 structural pathway	MYD88	TRAF6	MAP3K7	MAPK9	MAPK3	MAPKAPK2	NFKBIB	MAP2K4	MAPK8	MAPK14	ATF2	ELK1	IKBKB	MAPK10	MAPK11	CHUK	FOS	MAP2K7	EIF4E	RELA	MAP2K6	MAP2K3	MAP3K1	NFKBIA	MYC	IL1A	IL1R1	RPS6KA5	MBP	IL1RAP	TANK	IRAK1	IRAK2	MKNK1	MKNK2	MAP3K8	MAP3K3	IRF7	SAFB	TOLLIP	IRAK4	TAB3	MAP2K2;MAP2K1	NFKB1	TAB2	MAPK1	TAB1	MAP3K14	
GABA METABOLISM AKA GHB %WIKIPATHWAYS_20260910%WP4157%HOMO SAPIENS	GABA metabolism aka GHB	PON3	ALDH5A1	MAOB	GLS2	GAD1	GLS	ADHFE1	DPEP1	GAD2	ABAT	AKR7A2	
NCRNAS INVOLVED IN STAT3 SIGNALING IN HEPATOCELLULAR CARCINOMA%WIKIPATHWAYS_20260910%WP4337%HOMO SAPIENS	ncRNAs involved in STAT3 signaling in hepatocellular carcinoma	JAK2	IL6R	JAK1	IL11RA	ZEB1	STAT3	IL11	JAK3	IL6	RELA	IL6ST	SOX4	NFKB1	
CELLULAR PROTEOSTASIS%WIKIPATHWAYS_20260910%WP4918%HOMO SAPIENS	Cellular proteostasis	PFDN5	PFDN6	PFDN4-1	VBP1	PFDN1	PFDN2	
CHRONIC HYPERGLYCEMIA IMPAIRMENT OF NEURON FUNCTION%WIKIPATHWAYS_20260910%WP5283%HOMO SAPIENS	Chronic hyperglycemia impairment of neuron function	SLC2A1	PRKCA	C3-1	PRKCQ	AGER	PRKCD	PRKCZ	MMP1	MMP21	MMP20	MMP25	MMP24	MMP27	MMP2	MMP28	BDNF	SCN9A	TKTL1	MMP9	MMP7	TRPA1	MMP3	SORD	TRPV1	MMP8	MMP10	MMP12	NOS2	MMP11	SCN10A	MMP14	MMP13	MMP16	PRKD3	MMP15	SNAP25	MMP23B	SCN8A	MMP17	MMP19	PRKCG	PRKCI	PRKCH	PRKCB	PRKCE	
AMINO ACID CONJUGATION OF BENZOIC ACID%WIKIPATHWAYS_20260910%WP521%HOMO SAPIENS	Amino acid conjugation of benzoic acid	GLYAT	ACSS2	
SUZETRIGINE MECHANISM FOR PAIN RELIEF%WIKIPATHWAYS_20260910%WP5558%HOMO SAPIENS	Suzetrigine mechanism for pain relief	SCN10A	
NAD METABOLISM%WIKIPATHWAYS_20260910%WP3644%HOMO SAPIENS	NAD metabolism	PARP1	NRK	SIRT4	SIRT5	NMNAT3	SIRT1	NMNAT2	SIRT2	SIRT3	SIRT6	NMNAT1	NAMPT	CD38	NADK	NT5E	
FOCAL ADHESION PI3K AKT MTOR SIGNALING%WIKIPATHWAYS_20260910%WP3932%HOMO SAPIENS	Focal adhesion PI3K Akt mTOR signaling	PFKFB2	PRKAA1	ATF2	PPARGC1A	IKBKB	FGF21	JAK3	RHEB	PRKAA2	EGF	FN1	LIPE	EPO	TNC	KDR	PDGFB	ULK1	PDGFRB	FGF2	ATF4	KIT	IGF1	EIF4E	CREB3L2	RAF1	IRS4	AKT2	AKT3	AKT1	MTOR	GSK3B	TCL1B	PIK3R2	TCL1A	PIK3R1	PPP2R1B	PPP2R1A	DDIT4	PPP2R2A;PPP2R2D	MAP2K2;MAP2K1	EPHA2	MAPK1	EPAS1	LPAR2	JAK2	LPAR3	IL6R	LPAR4	GNG10	PDGFD	MAPK3	PDGFC	JAK1	NGFR	GNG13	COL1A1	COL1A2	LPAR5	BAD	LPAR6	CAB39L	HIF3A	GYS2	GNGT1	GYS1	IKBKG	RAB8A	STRADA	OSMR	PHLPP2	IGF1R	RPS6KB1	TNXB	GRB2	PHLPP1	CAB39	COL11A1	COL11A2	SOS1	RELN	VEGFB	OSM	VEGFD	RAB11B	KITLG	COL3A1	FGF20	CHRM2	NOS2	CSF3R	IL2	STK11	FGF22	IBSP	TNN	FGF17	TNR	FGF16	RAB2A	PDGFRA	FGF19	F2R	FLT4	COL4A2	COL4A1	PTEN	EIF4E1B	COL4A4	COL4A6	PFKFB1	FGF1	CSF1R	FGF3	PFKFB4	FGF4	PFKFB3	EFNA4	EGFR	FGF6	HSP90B1	FGF7	VTN	FGF8	CHAD	FGF9	EFNA1	EFNA3	EFNA2	FGF14	COL5A1	COL5A3	GNB2	COL5A2	GNB1	RPS6KB2	GNB4	EFNA5	GNB3	IL7R	FGF13	FGF12	FGF11	HSP90AB1	LAMC3	SLC2A2	PIK3R4	LAMC2	LAMC1	ELAVL1	GHR	PIK3R5	HSP90AA1	VWF	PPP2R5B	PPP2R5A	PPP2R5D	NGF	TBC1D1	COL6A2	IL3RA	EIF4E2	CREB5	LAMA5	LAMA2	LAMA1	LAMA4	LAMA3	THBS2	THBS4	SLC2A4	THBS3	ITGA2B	GNG2	GNG5	FGF18	PPP2R3C	FGFR4	GNG4	GNG8	FGFR3	EIF4B	FGFR2	ANGPT4	LAMB3	FGF10	NOS3	FGFR1	LAMB2	LAMB1	FOXO3	PPP2R3A	PIK3CD	EPOR	RAB10	PIK3CB	PPP2R2C	PIK3C2A	RAB14	PIK3CG	PIK3IP1	PPP2R2B	PIK3C2B	TEK	PPP2R5E	PPP2R5C	PTK2	CRTC2	PIK3CA	ITGA10	FLT1	ITGA11	ITGB1	ITGAM	PGF	ITGB5	ITGB4	ITGB3	ITGB2	ITGAE	ITGAL	ITGAX	ITGB8	ITGAV	ITGB7	ITGB6	ITGA4	PDPK1	ITGA3	ITGA2	CDKN1A	CDKN1B	ITGAD	ITGA8	ITGA7	ITGA6	CASP9	ITGA5	ITGA9	COMP	CREB1	IFNB1-4	MDM2-2	CHRM1	FOXA1	SREBF1	IRS1	IRS2	FOXO1-1	ACACA	INS;INS-IGF2	PPP2CB;PPP2CA	IFNAR2	NOS1	TSC2	IFNAR1	PRL	IL2RG	RPS6	IL4R	PRLR	EIF4EBP1	IL2RA	IL2RB	CSF3	HGF	CREB3L3	CREB3L4	CREB3L1	PDGFA	INSR	ATF6B	SPP1	CSF1	VEGFA	SLC2A1	LPAR1	NRAS	HIF1A	HRAS	KRAS	MET	RPTOR	MLST8	COL2A1	CDC37	ANGPT2	TSC1	ANGPT1	THBS1	VEGFC	CREB3	AKT1S1	
MAPK PATHWAY IN CONGENITAL THYROID CANCER%WIKIPATHWAYS_20260910%WP4928%HOMO SAPIENS	MAPK pathway in congenital thyroid cancer	RAF1	MYC	MAPK3	ELK1	FOS	SOS2	KSR1	GAREM2	KRAS	BRAF	JUN	ALK	SOS1	SHC1-1	MAP2K2;MAP2K1	
INVOLVEMENT OF SECRETASE IN NEURODEGENERATIVE DISEASES%WIKIPATHWAYS_20260910%WP5372%HOMO SAPIENS	Involvement of secretase in neurodegenerative diseases	SNCA	MAOB	STAT1	BACE1	AKT2	AKT3	AKT1	MAPT	SRPK2	NTRK2	BDNF	APP	SET-1	TARDBP	LGMN	CEBPB	PPP2CB;PPP2CA	
METHIONINE DE NOVO AND SALVAGE PATHWAY%WIKIPATHWAYS_20260910%WP3580%HOMO SAPIENS	Methionine de novo and salvage pathway	TAT	IL4I1	MTAP	MAT2A	SMS	ADI1	MSRB2	AHCY	MSRB3	ENOPH1	MAT2B	MTR-1	BHMT	SRM	CHDH	MAT1A	AMD1	APIP	MRI1	ODC1	TXN	MSRA	
CIRCADIAN RHYTHM GENES%WIKIPATHWAYS_20260910%WP3594%HOMO SAPIENS	Circadian rhythm genes	PRKAA1	PPARGC1A	EP300	AGRP	PRKAA2	NRIP1	ATF4	HNF1B	MAPK8	JUN	PROX1	NAMPT	GSK3B	HDAC1	NGFR	TPTEP2-CSNK1E;CSNK1E	NR2F6	IL6	PHLPP1	SKP1	NOS2	PTEN	PRKCG	AHCY	PRKDC	TYMS	ID4	HS3ST2	RORC	RORA	PPARG	MAPK9	PRF1	HNRNPU	CCAR2	HTR7	PROK2	BTRC	PROK1	UTS2R	MAPK10	CPT1A	METTL3	SOX14	CSNK1D	CLDN4	ATF5	UBA52	CLOCK	DHX9	MAGED1	NKX2-1	OGT-1	EGR1	JUND	EGR3	HOMER1	ROCK2	NR1D2	NR1D1	SETX	STAR	CUL1	NMS	HNRNPD	ID3	FBXL3	ADA	ID2-1	TOP2A	CREB1	SUV39H2	BHLHE41	PRMT5	NCOA2	KCND2	TP53	PAX4	MC3R	NCOR1	KCNMA1	AVP	PPARA	CIPC	DDC	ADCY1	ARNTL2	RELB	ARNTL	CST3	NPS	PROKR1	PROKR2	NFIL3	PML	SIK1;SIK1B	RPS27A	UBB;UBC	ARNT2	CAVIN3	NR1H3	HDAC2	TPH1	PPP1CA	CDK4	PER2	PER1	CHRM1	MYBBP1A	GHRH	FAS	GHRL	LGR4	EZH2	CRTC1	NPY2R	UBE3A	RORB	PPP1CB	PPP1CC	SREBF1	NAGLU	ADORA1	CHRNB2	FBXW11	MTTP	KCNH7	ADIPOQ	USP2	DYRK1A	CARTPT	TPH2	SLC9A3	MTNR1A	MTNR1B	PSPC1	TIMELESS	DDX5	MAGEL2	KMT2A	SLC6A4	CREM	TNFRSF11A	NPAS2	RAI1	AANAT	DRD1	DRD2	DRD3	DRD4	ZFHX3	OPN4	OPN3	ADORA2A	TH	NONO	GFPT1	BTBD9	BHLHE40	RBM4;RBM4B	KDM5A	HEBP1	DBP	SIN3A	SIX3	SFPQ-1	KLF10	ARNT	THRAP3	CRY2	CRY1	CRH	TOP1	NLGN1	HDAC3	CRX	OPRL1	CIART	ATOH7	MTA1	SERPINE1	GNA11	NOCT	NTRK1	NTRK3	HCRTR2	HCRTR1	LEP	KLF9	SFTPC	F7	AHR	PTGDS	SIRT1	GNAQ	SUV39H1	PRKG2	
OREXIN RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP5094%HOMO SAPIENS	Orexin receptor pathway	EIF4EBP1	MAPK9	MAPK3	MAPK7	PRKAA1	GNA11	NPY	PRKCD	MAPK14	STAT3	HCRTR2	HCRTR1	PDPK1	PTPN11	LEP	NPFFR1	DAGLA	PLCD1	ARRB1	POMC	ARRB2	SGK1-1	IL6	FSHB	RPS6KB1	RRAGC	LHB	CASP9	SLC1A2	PDHB	PLD1	CAMKK2	NPVF	CASP3	IL10	VHL	CGA	CXCL8	HCRT	OPRK1	GCG	CCK	STAR	IL9	GNRH1	IL4	CREB1	BMP7	TNF	NFE2L2	CXCL2;CXCL3;CXCL1-1	NOX4	PRKCB	PRKCE	SLC2A1	PRKCA	RUNX2	IL1B	PRKD1	GRIA1	GNAI1	MAPK8	HIF1A	GHRL	PRKCZ	GNAS-1	RPS6KA1	GNAQ	SMAD1	ADIPOQ	FOXO1-1	DYNLT1	SLC2A4	SMAD5	EIF4B	BMPR1A	PDK1	TH	MTOR	RPS6	PIK3R2	PIK3R1	MAP2K2;MAP2K1	MAPK1	
EFFECTS OF MFN2 MUTATION%WIKIPATHWAYS_20260910%WP5443%HOMO SAPIENS	Effects of MFN2 mutation	SNCA	RAB3B	DCTN1	ATAT1	DYNC1LI2	RHOT1	SYPL1	RAB3A	CASP8	MAP2	BAX	KIF1B	RABAC1	RAB7A	TP53	DYNC1I1	TUBB3;TUBB6	DYNC2H1	MFN2	DYNC2I2	DYNC1H1	DYNC2I1	TRAK1	CASP3	
INITIATION OF TRANSCRIPTION AND TRANSLATION ELONGATION AT THE HIV 1 LTR%WIKIPATHWAYS_20260910%WP3414%HOMO SAPIENS	Initiation of transcription and translation elongation at the HIV 1 LTR	HDAC3	HDAC2	PPP3CA	PPP3CB	PPP3CC	CREBBP	EP300	NFATC2	RELA	NFKBIA	NFATC1	SP1	HDAC4	HDAC5	CCNT1	HDAC8	HDAC9	PPP3R1	HDAC7	NELFB	NELFA	NELFCD	HDAC1	NELFE	SUPT4H1-1	HEXIM1	NFATC3	SUPT5H	NFATC4	NFKB1	CDK9	
THYROXINE THYROID HORMONE PRODUCTION%WIKIPATHWAYS_20260910%WP1981%HOMO SAPIENS	Thyroxine thyroid hormone production	PRKCA	CLCN5	SLC26A6	MAPK3	PRKAA1	SLC5A5	TPO	ELK1	DUOX2	TSHR	PLCD1	TG	PRKAA2	CGA	TRH	RAF1	CREB1	RAP1B	RAP1A	ACY1;ABHD14A-ACY1	MAP2K2;MAP2K1	NFKB1	DUOX1	MAPK1	ANO1	
DISRUPTION OF POSTSYNAPTIC SIGNALING BY CNV%WIKIPATHWAYS_20260910%WP4875%HOMO SAPIENS	Disruption of postsynaptic signaling by CNV	NLGN1	NLGN3	CAMK2B	CYFIP1	MAPK3	RYR2	CAMK2D	NLGN2	FMR1	CAMK2A	NRXN3	NRXN2	GRM1	RPH3A	SYNGAP1	DLGAP1	CAMK2G	NLGN4X;NLGN4Y	NRXN1;NRXN3;NRXN2	TJP1	ARC	DLG1	DLG2	SHANK1	HOMER1	GRIN1	GRIN2A	STX1A	YWHAG	GRIN2C	GRIN2B	GRIN2D	MAPK1	
KININ KALLIKREIN PATHWAY%WIKIPATHWAYS_20260910%WP5089%HOMO SAPIENS	Kinin Kallikrein pathway	KNG1	F12	BDKRB2	SERPING1	KLKB1	CPN1	BDKRB1	
ESTROGEN RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2881%HOMO SAPIENS	Estrogen receptor pathway	SP1	STAT3	ACOX1	CYP1A2	CYP1B1	CYP1A1	PPARA	JUN	NR0B2	GPAM	ESR1	PDK4	PCK1	
SARS COV 2 ENVELOPE LIPID COMPOSITION AND HUMAN CELL BINDING%WIKIPATHWAYS_20260910%WP5255%HOMO SAPIENS	SARS CoV 2 envelope lipid composition and human cell binding	AXL	
CLASSICAL PATHWAY OF STEROIDOGENESIS WITH GLUCOCORTICOID AND MINERALOCORTICOID METABOLISM%WIKIPATHWAYS_20260910%WP4523%HOMO SAPIENS	Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism	CYB5A	H6PD	CYP19A1	STAR	SRD5A2	HSD17B3	HSD11B1	CYP17A1	HSD11B2	POR	HSD3B1;HSD3B2	CYP11A1	CYP21A2	CYP11B1;CYP11B2	
OLIGODENDROCYTE DEVELOPMENT%WIKIPATHWAYS_20260910%WP5574%HOMO SAPIENS	Oligodendrocyte development	PRKCA	BMP4	MAG	NFATC2	SOX11	SOX2	SMAD1	BMP1	WNT10A	ID4	RELN	ID2-1	MYRF	PDGFRA	CHD8	CHD7	ASCL1	PTN	FGF2	EGR2	ZNF24	DUSP15	GLI2	SHH	PTPRZ1	SOX8	NKX6-1	ZEB2	MBP	ZNF488	SOX9	LGI1	SOX6	OPALIN	SOX5	ZBTB33	NKX2-2	TMEM98	NKX2-6	NFIA	CNTN1	CSPG4	HES5	TCF7L2	OLIG1	OLIG2	MYT1	SOX10	
GLUCOSE HOMEOSTASIS%WIKIPATHWAYS_20260910%WP661%HOMO SAPIENS	Glucose homeostasis	INS;INS-IGF2	
GASTRIC CANCER NETWORK 2%WIKIPATHWAYS_20260910%WP2363%HOMO SAPIENS	Gastric cancer network 2	BRIX1	UBE2C	ATAD2	FANCI	CACYBP	FAM91A1	RNF144B	UBE2T	SNURF	CEBPZ	RAD17	CD48	LBR	CTNNB1	RFC3	RFC4	MYC	TOP2A	COL9A1	COL9A3	TP53	EGFR	OTUD5	AHCTF1	S100A6	DSCC1	CHTF18	LMNB2	MTDH	PLAC8	
ESTROGEN SIGNALING%WIKIPATHWAYS_20260910%WP712%HOMO SAPIENS	Estrogen signaling	GNB1	MAPK9	PRKACA-1	SP1	CREB1	GPER1	MAPK14	ELK1	IKBKB	GNGT1	AKT1	CHUK	GNAS-1	IKBKG	FOS	BRAF	JUN	PIK3CA	NFKB1	MAP2K2;MAP2K1	BCL2	ESR1	MAPK1	
LNCRNA MEDIATED MECHANISMS OF THERAPEUTIC RESISTANCE%WIKIPATHWAYS_20260910%WP3672%HOMO SAPIENS	lncRNA mediated mechanisms of therapeutic resistance	CDKN1A	HIF1A	BCL2L1	ABCB1	WNT6	TP53	
BMP SIGNALING IN EYELID DEVELOPMENT%WIKIPATHWAYS_20260910%WP3927%HOMO SAPIENS	BMP signaling in eyelid development	BMP4	TGFA	SMAD5	MAPK9	MAPK3	NOTCH1	DKK2	FGFR2	FGF10	FOXC2	FOXC1	INHBB	PITX2	SHH	SMAD1	EGFR	SFRP1	SMAD4	JUN	MAP3K1	
DENGUE 2 INTERACTIONS WITH COMPLEMENT AND COAGULATION CASCADES%WIKIPATHWAYS_20260910%WP3896%HOMO SAPIENS	Dengue 2 interactions with complement and coagulation cascades	C3-1	C1QC	SERPINA1	SERPINE1	PLAT	PLAU	PROS1	CLU	FGB	SERPINA5	C8G	C3AR1	LOC110384692;C4A;C4B_2;C4B	CR2	SERPINF2	PLAUR	F2	F3	F7	F5	F8	PLG	F9	MASP2	MASP1	CFB	CFD	C1QB	CPB2	C1S	C1R	SERPINC1	CFI	C5AR1	TFPI	C2	LMAN1	F2R	C6	CLTC	C7	C9	CD55	F10	SERPIND1	CR1L;CR1	PROC	F13B	CFH-3	KNG1	VWF	F12	SERPING1	KLKB1	THBD	BDKRB1	APOA2	
NEUROTRANSMITTER DISORDERS%WIKIPATHWAYS_20260910%WP4220%HOMO SAPIENS	Neurotransmitter disorders	SLC6A3	SLC18A2	PNMT	COMT	DDC	TPH1	MAOA	TPH2	TH	DBH	
CODEINE AND MORPHINE METABOLISM%WIKIPATHWAYS_20260910%WP1604%HOMO SAPIENS	Codeine and morphine metabolism	ABCC3	ABCC2	CYP2D6;LOC107987479;LOC107987478-1	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	ABCB1	UGT1A1;UGT1A6	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
VITAMIN B6 DEPENDENT AND RESPONSIVE DISORDERS%WIKIPATHWAYS_20260910%WP4228%HOMO SAPIENS	Vitamin B6 dependent and responsive disorders	PDXK	PNPO	ALPL	PLPBP	ALDH7A1	PIGV	ALPG;ALPP;ALPI-1	
WNT SIGNALING NETPATH%WIKIPATHWAYS_20260910%WP363%HOMO SAPIENS	Wnt signaling NetPath	PRKCA	TCF4	ROR1	MAP3K7	CDK6	ROR2	MAPK9	PI4K2A	CSNK1G1	MAPK8	PIP5K1B	NFATC2	CTNNB1	TPTEP2-CSNK1E;CSNK1E	RHOA	CSNK1D	ARRB2	DVL1	DVL2	CCND1	DVL3	TSC2	LRP6	AKT1	MTOR	AXIN1	TSC1	LEF1	GSK3B	PRKCG	GSK3A	CTBP1	NLK	TCF7L2	PPARG	SOX1	LRP5	GCKR	CSNK1A1	MAPK1	PRKCB	RYK-1	RAC1	BCL9	APC	
FGFR4 P G388R SIGNALING%WIKIPATHWAYS_20260910%WP5428%HOMO SAPIENS	FGFR4 p G388R signaling	FGFR4	STAT3	IL10	
GLYCEROPHOSPHOLIPID BIOSYNTHETIC PATHWAY%WIKIPATHWAYS_20260910%WP2533%HOMO SAPIENS	Glycerophospholipid biosynthetic pathway	PI4K2A	MOGAT3	PLA2G2A-1	PGS1	PTDSS1	GPAT4	PIP5K1A	PTPMT1	GPAT3	GPAT2	CEPT1	CDIPT	CHKB	PCYT2	GK	IPMK	CRLS1	GNPAT	GPD1	AGPS	PEMT	CHPT1	LPIN1	LPIN2	CDS2	GPAM	PIK3CD	PIK3CB	PIK3CG	PIK3CA	
PPAR SIGNALING%WIKIPATHWAYS_20260910%WP3942%HOMO SAPIENS	PPAR signaling	UBB;UBC	APOA5	ILK	EHHADH-1	UCP1	NR1H3	CYP7A1	ANGPTL4	RXRA	PLTP	CD36	ACAA1-1	ACOX1	PDPK1	PPARD	MMP1	GK	CYP8B1	APOA1	ADIPOQ	SLC27A1	RXRB	CPT2	OLR1	SLC27A5	ME1	PCK1	HMGCS2	RXRG	APOC3	CPT1C	FABP1	FABP3	FADS2	FABP4	ACSL1	SCD	SORBS1	SLC27A4	SCP2	PCK2	PPARA	LOC100509620;LOC112267859;AQP7	CYP27A1	PPARG	APOA2	LPL	PLIN1	
RESOLVIN E1 AND RESOLVIN D1 SIGNALING DECREASE INFLAMMATION%WIKIPATHWAYS_20260910%WP5191%HOMO SAPIENS	Resolvin E1 and resolvin D1 signaling decrease inflammation	MTOR	PIK3CG	GRK1	PIK3CA	FPR2	EPHB2	PDK1	LTB4R	PIK3CD	CMKLR1	AKT1	PIK3CB	
ID SIGNALING%WIKIPATHWAYS_20260910%WP53%HOMO SAPIENS	ID signaling	ELK4	ID3	CDK2	ID2-1	RBL2	ELK1	CCNE1	PAX5	ELK3	RB1	SREBF1	PAX2	RBL1	ID1	MYOD1	PAX8	
CATABOLISM OF SKELETAL MUSCLE IN CACHEXIA%WIKIPATHWAYS_20260910%WP5474%HOMO SAPIENS	Catabolism of skeletal muscle in cachexia	IL6R	IL1B	JAK1	STAT3	IKBKB	EP300	MAPK11	IKBKG	CHUK	TNFRSF1A	IL6	IGF1R	RELA	SMAD4	NFKBIA	CEBPB	SMAD2;SMAD3	RPTOR	IL1A	IL1R1	FBXO32	MLST8	PDK1	FOXO3	TNF	AKT1	MSTN	MTOR	MAP1LC3A	TRIM63	TNFRSF12A	ACVR2A	REL	RELB	IGF1	AKT1S1	NFKB1	NFKB2	
BIOGENIC AMINE SYNTHESIS%WIKIPATHWAYS_20260910%WP550%HOMO SAPIENS	Biogenic amine synthesis	COMT	TPH1	GAD1	AANAT	GAD2	TH	PNMT	DDC	MAOA	HDC	CHAT	ASMT	PAH	ACHE	DBH	
ANDROGEN RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP138%HOMO SAPIENS	Androgen receptor signaling	ZMIZ1	RACK1	PIAS4	NCOA4	ETV5	PIAS2	NCOA1	TLE5	RHOB	NCOR2	CREBBP	AR	ZNF318	FKBP4	RNF6	STAT3	RNF4	NR2C2	EP300	PSMC3IP	PRDX1	CTNNB1	RB1	BAG1	RLN2;RLN1	PATZ1	SMARCE1	UBE2I	BRCA1	LIMK2	RELA	DSTN	CARM1	FLNA	STUB1	RAN	ROCK1	ROCK2	SRC	CDC42	CCND1	SP1	CREB1	PTEN	NCOA2	CCNE1	PARK7	NCOA3	MDM2-2	NCOR1	EGFR	RUNX2	UBE3A	RAD9A	SIRT1	RHOA	SMAD4	FOXO1-1	JUN	TGFB1I1	NR0B2	KDM1A	BUB1B-PAK6;PAK6	SMAD2;SMAD3	KAT2B	TGIF1-1	PIAS1	AKT1	DAXX	GSK3B	SIN3A	PIAS3	HDAC1	CAV1	PIK3R2	PIK3R1	PTK2	CALR-1	RNF14	FHL2	EFCAB6	KAT5	SMIM40	SUMO1	RAC1	
ENVELOPE PROTEINS AND THEIR POTENTIAL ROLES IN EDMD PHYSIOPATHOLOGY%WIKIPATHWAYS_20260910%WP4535%HOMO SAPIENS	Envelope proteins and their potential roles in EDMD physiopathology	ADCY3	MAPK3	ADCY8	NRAS	HRAS	WWTR1	CCN2	LBR	RHOA	MAP3K9	KRAS	SMAD4	GRB2	SOS1	ADCY4	ADCY2	SYNE4	SYNE3	ADCY7	ADCY6	SMAD2;SMAD3	SYNE2	SYNE1	ADCY5	TMEM43	CFL1	BANF1	EMD	TMPO	SUN1	LEMD3	ADCY10	ADCY9	KIF5B	PLEC	SOS2	ADCY1	TGFB2	TGFB1	TGFB3	MAP2K2;MAP2K1	MAPK1	SRF	
ANDROGEN BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP5393%HOMO SAPIENS	Androgen biosynthesis	SRD5A2	AKR1D1	HSD17B2	HSD17B3	HSD11B1	CYP17A1	HSD11B2	POR	HSD3B1;HSD3B2	SRD5A1	HSD17B4	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	HSD17B1	SULT2A1-4	CYP11B1;CYP11B2	
FLAVAN 3 OL METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP4238%HOMO SAPIENS	Flavan 3 ol metabolic pathway	COMT	
LNCRNA LIKE NMRK2 IN TRANSLOCATION RENAL CELL CARCINOMA%WIKIPATHWAYS_20260910%WP5519%HOMO SAPIENS	LncRNA like NMRK2 in translocation renal cell carcinoma	CS	MDH2	NMRK2	HSPE1	SLC19A2	FH	NONO	TFE3	
GABA RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP4159%HOMO SAPIENS	GABA receptor signaling	GABRA1	GABRP	AP2B1	GABBR1	GABRA6	GABRA5	GAD1	GABRA4	GABRA3	SLC6A11	GAD2	GABRG1	ABAT	ALDH9A1	AP2S1	SLC6A1	AP2A1	AP2A2	AP2M1	GABRB3	GABRB2	GABRB1	GPHN	GABRG3;GABRG2	SLC32A1	GABRE	GABRD	GABRQ	GABRA2	GABBR2	
SIGNALING LIPIDS%WIKIPATHWAYS_20260910%WP5584%HOMO SAPIENS	Signaling lipids	HPGD	ALOX15	ALOX12	LTC4S	CYP7A1	CYP2B6	ALOX5	PLA2G1B	LTA4H	PTGDS	CBR1-1	PLA1A	EPHX2	CYP4F3;CYP4F2;CYP4F12;CYP4F11	PRXL2B	PLCB1	CYP8B1	TBXAS1	GPX4	PTGS2-2	FADS2	CYP2C9;CYP2C19	CYP7B1	CYP27A1	PTGES	
SULINDAC METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP2542%HOMO SAPIENS	Sulindac metabolic pathway	CYP1B1	FMO3	MSRB2	MSRB3	CYP1A2	MSRA	
NO CGMP PKG MEDIATED NEUROPROTECTION%WIKIPATHWAYS_20260910%WP4008%HOMO SAPIENS	NO cGMP PKG mediated neuroprotection	NPR1	CAMK2B	IL1B	CAMK2D	CAMK2A	BAD	GUCY1B1	XIAP	AKAP9-1	NPPA	CAMK2G	CNGA1	CNGA2	CNGA3	CNGA4	GUCY1A2	GUCY1A1	RELA	ACTN2	CASP9	PDE2A	DLG4	PDE3A	CNGB3	TSPO	NFKBIA	CNGB1	NEFL	BCL2	NOS2	GRIN1	NPPB	NOS1	IFNG	NOS3	CREB1	PRKG2	TNF	CYCS-1	GRIN2A	PPID	GRIN2C	GRIN2B	GRIN2D	NFKB1	CALM1	
DISORDERS OF FRUCTOSE METABOLISM%WIKIPATHWAYS_20260910%WP5178%HOMO SAPIENS	Disorders of fructose metabolism	KHK	PFKL	ALDOB	FBP1	SLC2A2	HK1	PGM1	G6PC1	ALDH1A1	TPI1	SORD	GLYCTK	GPI	SLC5A1-1	
IL11 SIGNALING%WIKIPATHWAYS_20260910%WP2332%HOMO SAPIENS	IL11 signaling	JAK2	RUNX2	MAPK3	JAK1	STAT1	IL11RA	ICAM1	HRAS	STAT3	IKBKB	YES1	PDPK1	PTPN11	TYK2	ITGA2	CHUK	RPS6KA1	RPS6KB1	RELA	GRB2	IL6ST	FES	BCL2	SRC	RAF1	ATF1	PTPA	IBSP	BIRC5	CREB1	FYN	IL11	PIAS1	AKT1	PIAS3	PIK3R2	RPS6	PIK3R1	TGFB1	SOCS3	MAP2K2;MAP2K1	MAPK1	
GLYCEROLIPIDS AND GLYCEROPHOSPHOLIPIDS%WIKIPATHWAYS_20260910%WP4722%HOMO SAPIENS	Glycerolipids and glycerophospholipids	CDS1	DGAT2	PTDSS1	DGAT1	GPAT4	PLA2G1B	DGKZ	PISD	AGPAT4	PTDSS2	ETNK1	CDIPT	CHKB	PNPLA3	PCYT2	CRLS1	PEMT	PNPLA2	CHPT1	PLD1	PCYT1A	GPAM	
MEVALONATE ARM OF CHOLESTEROL BIOSYNTHESIS PATHWAY WITH INHIBITORS%WIKIPATHWAYS_20260910%WP4189%HOMO SAPIENS	Mevalonate arm of cholesterol biosynthesis pathway with inhibitors	MVD	HMGCR	
RESISTIN AS A REGULATOR OF INFLAMMATION%WIKIPATHWAYS_20260910%WP4481%HOMO SAPIENS	Resistin as a regulator of inflammation	MAPK3	PLCG2	PLCG1	MAPK14	IL12B	PLCB3	IKBKB	PLCB4	PLCD3	PLCD4	IKBKG	CHUK	PLCD1	PLCB1	IL6	PLCB2	RELA	NFKBIA	CXCL8	IL12A	PIK3CD	TNF	AKT2	AKT3	PIK3CB	AKT1	PIK3CG	RETN	PLCE1	PIK3CA	ITPR1	NFKB1	MAPK1	
ECTODERM DIFFERENTIATION%WIKIPATHWAYS_20260910%WP2858%HOMO SAPIENS	Ectoderm differentiation	MZF1	ASTN1	LY6E	ARX	GATA6	STC1	ARHGAP15	ZBTB2	TRPM2	SDCBP	PODXL	ST8SIA4	HESX1	PLXNA2	ZBTB7B	GAS2L1	PPARD	TFAP2A	CTNNB1	TFAP2C	JUP	SMURF1	ZBTB16	GREB1	NR2F2	POU2F2	ZFHX4	PAN2	OGT-1	AHI1	PLCXD3	PRKAG2	PTPRB	PPFIBP2	MAFB	CCDC88C	PI4KA	MKS1	MYC	CCDC130	EDA	NUMA1	HMGB2	LDB2	EDA2R	WDR44	PHF8	SIX6	BOC	UBTF	RAB8B	BCAS3	SHH	ELOVL4	TSC22D1	ELOVL2	PAX3	SORCS1	PAX6	BAZ1A	FOXL1	RGMA	CLDN11	ARHGAP10	TOX3	CTBP1	KIFC3	STX16	RRBP1	JAKMIP1	HDAC6	BMP4	IQCJ-SCHIP1;SCHIP1	DMD	ROR2	SERPINB6-2	CLVS1	CAP2	TTC14	C1GALT1	PTPN13	VAX2	LHX1	RIT1	GLB1	SGSM3	ZNF219	SPRY2	BCOR	PDE7A	TRIM33	MYORG	ABCC4	SOX2	TNFRSF11B	FOXA2	CTNNA2	FYN	CCL13;CCL2	NLK	FHL2	SOCS2	NLGN1	TLE5	MECP2	CDH6	SNCA	SKIL	TCF7L1	PGM1	WNT1	SMAD4	NF2	FZD5	FZD4	FZD8	NFATC1	FGFR2	BMPR1A	GLI3	HDAC10	CTNND2	ARHGDIG	CELSR2	TSKU	CDH8	NARS2	PIM1	ANKS1B	CDON	KCNK10	GRAMD1B-1	KRT6B;KRT6C;KRT6A	
METABOLIC PATHWAY OF LDL HDL AND TG INCLUDING DISEASES%WIKIPATHWAYS_20260910%WP4522%HOMO SAPIENS	Metabolic pathway of LDL HDL and TG including diseases	LIPC	APOC2	SCARB1	ANXA2	PCSK9	LIPG	APOA1	LDLRAP1	MTTP	CETP	APOA2	APOE	APOB	LPL	LDLR	ABCA1	LCAT	
AMP ACTIVATED PROTEIN KINASE SIGNALING%WIKIPATHWAYS_20260910%WP1403%HOMO SAPIENS	AMP activated protein kinase signaling	EIF4EBP1	PRKAA1	GYS2	LEP	CPT1A	GYS1	CDKN1A	STRADA	RPS6KB1	PRKAA2	CAB39	PRKAG1	CCNA1	PRKAG2	CAMKK2	PRKAG3	PRKACB-1	LIPE	PRKAB2	INSR	STK11	PRKAB1	HNF4A	TP53	CCNA2-1	PFKFB3	CCNB1	RPS6KB2	PIK3R3	ELAVL1	SREBF1	PLCB1	ADRA1A	EEF2K	ADIPOQ	LEPR	STRADB	ACACA	INS;INS-IGF2	CPT1B	ADIPOR1	ACACB	FASN	ADIPOR2	CAMKK1	PPARGC1B	EEF2	SLC2A4	SLC2A4RG	ADRA1B	RPTOR	CPT1C	TSC2	PIK3CD	AKT2	PIK3CB	AKT1	MTOR	PIK3CG	HMGCR	TSC1	PIK3R2	CRTC2	PIK3CA	PIK3R1	PIK3C3	
NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN NOD PATHWAY%WIKIPATHWAYS_20260910%WP1433%HOMO SAPIENS	Nucleotide binding oligomerization domain NOD pathway	IL1B	CASP8	DUOX2	CASP5;CASP4	XIAP	IKBKB	HSP90AA1	IKBKG	CHUK	RELA	CASP9	NOD2	NFKBIA	IL18	NDUFA13	NOD1	NLRC4	MEFV	NLRP7;NLRP2	NLRP4	NLRP1	AAMP	RIPK2	CARD9	ERBIN	CARD6	NLRP12	COPS6	ACAP1	AIM2	NLRP10	SUGT1	NAIP	PYCARD	CASP7	CASP1	NLRP3	PRDM1	RAC1	
PHOTODYNAMIC THERAPY INDUCED UNFOLDED PROTEIN RESPONSE%WIKIPATHWAYS_20260910%WP3613%HOMO SAPIENS	Photodynamic therapy induced unfolded protein response	TRIB3	ERP27	ATF3	BBC3	DDIT3	BCL2L11	ATF6	ATF4	NFE2L2	ERN1	PPP1R15A	HSP90B1	NARS1	XBP1	DNAJB9	EIF2AK3	EIF2A	HSPA5	UBE2E1	CALR-1	ASNS	EDEM1-1	PDIA6	WARS1	DNAJC3-1	DNAJB11	
PHOTODYNAMIC THERAPY INDUCED NFE2L2 NRF2 SURVIVAL SIGNALING%WIKIPATHWAYS_20260910%WP3612%HOMO SAPIENS	Photodynamic therapy induced NFE2L2 NRF2 survival signaling	GCLM	GSTP1	NQO2	SRXN1	ABCC6	NQO1	HMOX1	ABCG2	CES1	MAPK8	MAPK14	MAPK12	MAPK13	EPHX1	MAPK11	NFE2L2	ABCC3	KEAP1	ABCC4	FOS	ABCC2	JUN	GCLC	
AMYOTROPHIC LATERAL SCLEROSIS ALS %WIKIPATHWAYS_20260910%WP2447%HOMO SAPIENS	Amyotrophic lateral sclerosis ALS	GRIA1	PPP3CA	PPP3CB	PPP3CC	TOMM40	DERL1	NEFM	BAD	NEFH	MAPK14	BAX	PRPH	CCS	ALS2	RAB5A	TNFRSF1A	GPX1	MAP2K6	SLC1A2	CASP9	BCL2L1	CASP3	NEFL	BCL2	APAF1	NOS1	SOD1	TNF	TP53	MAP3K5	DAXX	CASP1	BID	CAT	CST3	MAP2K2;MAP2K1	SMIM40	RAC1	
PROGERIA ASSOCIATED LIPODYSTROPHY%WIKIPATHWAYS_20260910%WP5103%HOMO SAPIENS	Progeria associated lipodystrophy	SMAD2;SMAD3	ICMT	LMNA	BANF1	ZMPSTE24	PARP1	WRN	KCNJ6	POLD1	MUCL3	RECQL	LMNB1	FNTA	FFAR3;GPR42	SPRTN	SMAD4	FBN1	TGFB1	INS;INS-IGF2	PPARG	LMNB2	
ARYLAMINE METABOLISM%WIKIPATHWAYS_20260910%WP694%HOMO SAPIENS	Arylamine metabolism	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	CYP1A2	
RETINOL METABOLISM%WIKIPATHWAYS_20260910%WP5188%HOMO SAPIENS	Retinol metabolism	LRAT	RDH13	BCO1	CYP2A13;CYP2A6;CYP2A7-1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	ADH1C;ADH1B;ADH1A	CYP1A1	ALDH1A1	RPE65	DHRS4	SDR16C5	CYP2W1	DHRS9	RDH12	AWAT2	PNPLA4	AOX1	
FTO OBESITY VARIANT MECHANISM%WIKIPATHWAYS_20260910%WP3407%HOMO SAPIENS	FTO obesity variant mechanism	FTO	TBX1	UCP1	IRX5	IRX3	ARID5B	PRDM16	PPARGC1A	
CANCER IMMUNOTHERAPY BY CTLA4 BLOCKADE%WIKIPATHWAYS_20260910%WP4582%HOMO SAPIENS	Cancer immunotherapy by CTLA4 blockade	PIK3R3	PIK3CD	PTPN11	CD86	PIK3CB	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	CD80	CTLA4	PIK3R2	PIK3R1	PIK3CA	CD28	PPP2CB;PPP2CA	PTPN6	
LACTO SERIES SPHINGOLIPID METABOLISM%WIKIPATHWAYS_20260910%WP5303%HOMO SAPIENS	Lacto series sphingolipid metabolism	B3GALT2	B3GNT5	B3GALT1	FUT2	FUT1	FUT6;FUT5;FUT3	
SENESCENCE AND AUTOPHAGY IN CANCER%WIKIPATHWAYS_20260910%WP615%HOMO SAPIENS	Senescence and autophagy in cancer	MAPK14	RB1	CDKN1A	CDKN1B	CDC25B	FN1	SRC	ATG14	ATG13	ULK1	IFNB1-4	TP53	MDM2-2	IL3	E2F1	CXCL2;CXCL3;CXCL1-1	IGF1	BMP2	IL1B	MAP2K3	JUN	INS;INS-IGF2	BCL2	RAF1	KMT2A	MMP14	MTOR	MAP1LC3A	GSK3B	TGFB1	MAP2K2;MAP2K1	MAPK1	IL6R	SERPINE1	COL1A1	PLAT	PLAU	IL6	IGF1R	RB1CC1	IRF1	IL6ST	CCL3L1;CCL3L3;CCL3;CCL18	BECN1	CEBPB	CXCL8	AMBRA1	COL3A1	IL1A	IFNG	PTEN	SPARC	CXCL14	LAMP1	LAMP2	SLC39A2	SLC39A1	SLC39A4	SLC39A3	IGFBP3	SH3GLB1	ATG3	VTN	MAP1LC3B2;MAP1LC3B-1	GABARAPL2	ATG10	IRF7	ATG12-1	FKBP8	SQSTM1	GABARAP	ATG7	ATG5	UVRAG	TNFSF15	ATG16L1	IL24	BMI1	ING1	ING2	MAP1LC3C	COL10A1	SERPINB2	CD44	RNASEL	HRAS	IFI16	CREG1	IGFBP5	GSN	RSL1D1	SMAD4	SMAD2;SMAD3	MLST8	IGFBP7	THBS1	PCNA	INHBA	IRF5	CDKN2A	BRAF	AKT1S1	PIK3C3	
S1P RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260910%WP26%HOMO SAPIENS	S1P receptor signal transduction	MAPK3	GNAI1	MAPK7	MAPK6	MAPK4	MAPK12	PLCB3	ASAH1	SMPD2	RACGAP1	S1PR1	PLCB1	S1PR3	PLCB2	S1PR2	S1PR5	SPHK2	SPHK1	GNAI3	GNAI2	AKT2	AKT3	AKT1	PIK3C2B	MAPK1	
MICROTUBULE CYTOSKELETON REGULATION%WIKIPATHWAYS_20260910%WP2038%HOMO SAPIENS	Microtubule cytoskeleton regulation	PRKCA	MAPKAPK2	CDK1	NTRK1	NTRK3	STAT3	GNAQ	MAPT	TRIO	TESK2	AURKB	MAPRE1-1	ROCK1	SPRED1	PARD6A	SRC	DPYSL2	DVL1	CDC42	CFL2	PAK1	STMN1	RHO	TPPP	MARK2	CLASP1	PRKACA-1	MARK1	WNT3A	LIMK1	TIAM1	DIAPH1	CLIP1	PTPRA	EPHB2	TAOK1	PTEN	CAMK4	MAP1B	KIF2C	AKT1	PHLDB2	F2RL2	ABL1	GSK3B	NTRK2	RAC1	APC	
INTRACELLULAR TRAFFICKING PROTEINS INVOLVED IN CMT NEUROPATHY%WIKIPATHWAYS_20260910%WP4856%HOMO SAPIENS	Intracellular trafficking proteins involved in CMT neuropathy	MTMR2	NEFL	RAB11B	RAB3B	RAB3A	KIF1B	RABAC1	EGR2	RAB7A	LRSAM1	HSPB8	HSPB1	NDRG1	LITAF	FGD4	SH3TC2	RAB25	MFN2	MPZ	RAB4A	RAB4B	SBF2	GDAP1	RAB11A	FIG4	DNM2	PMP22	
COVID 19 STRUCTURAL COVERAGE MAP%WIKIPATHWAYS_20260910%WP5145%HOMO SAPIENS	COVID 19 structural coverage map	NRP1	IGHMBP2	UBB;UBC	MACROH2A2	MACROH2A1	MRM2	MACROD1	MACROD2	CMTR1	PAIP1	TOMM70	UPF2	UPF1	AQR	SLC6A19	ISG15	PARP14	PARP9	MPP5	GDAP2	APOA1	UBA52	NLRP12	ACE2	TAB1	
ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY%WIKIPATHWAYS_20260910%WP2118%HOMO SAPIENS	Arrhythmogenic right ventricular cardiomyopathy	ITGB3	CACNA1C	CACNA1F	ITGB8	ITGAV	ITGB7	ITGB6	CACNA1S	ITGA4	ITGA3	ITGA2	CTNNB1	DSP	ITGA1	JUP	ACTG1	CDH2	ATP2A2	GJA1	ITGA8	SGCD	SGCA	ITGA7	SGCB	ITGA6	DAG1	ITGA5	SGCG	ACTN3	ACTN1	CACNA2D1	ITGA9	CACNA2D3	CACNA2D2	TCF7	ACTN4	CACNA2D4	CACNB1	CACNB2	CACNB3	CACNB4	PKP2	DSG2	EMD	DSC2	CACNG6	SLC8A1	CACNG7	CACNG8	CACNG1	CACNG2	CACNG3	CACNG4	CACNG5	ACTB-1	LEF1	TCF7L2	TCF7L1	DMD	DES	RYR2	LMNA	ACTN2	LAMA2	ITGA2B	CTNNA1	CTNNA3	CTNNA2	ITGA10	ITGA11	ITGB1	CACNA1D	ITGB5	ITGB4	
PARKINSON 39 S DISEASE PATHWAY%WIKIPATHWAYS_20260910%WP2371%HOMO SAPIENS	Parkinson 39 s disease pathway	SYT11	UBB;UBC	UBA1	PINK1	MAPK14	MAPK12	MAPK13	MAPK11	CASP9	CASP3	SNCA	SLC6A3	APAF1	CCNE2	CCNE1	PRKN	PARK7	HTRA2	TH	UBA7	CYCS-1	LRRK2	UBE2L6	UBE2J2	DDC	UBE2J1	CASP7	UCHL1	ATXN2	CASP6	CASP2	GPR37	SEPTIN5	UBE2G1	UBE2G2	SNCAIP	EPRS1	
BIOSYNTHESIS AND REGENERATION OF TETRAHYDROBIOPTERIN AND CATABOLISM OF PHENYLALANINE%WIKIPATHWAYS_20260910%WP4156%HOMO SAPIENS	Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine	GCH1	MAOB	DNAJC12	COMT	PTS	QDPR	SPR	AANAT	DHFR2;DHFR	TH	PNMT	MAOA	ASMT	PAH	DBH	
MIR TARGETED GENES IN SQUAMOUS CELL%WIKIPATHWAYS_20260910%WP2006%HOMO SAPIENS	miR targeted genes in squamous cell	NRP1	PKM	SDCBP	PODXL	GAS2L1	RHEB	VCAM1	GNAI2	FGF2	AP2A1	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	YWHAQ	UBE2J1	MAP3K8	SLC38A1	TUBA1A	CPNE8	VEZT	ACAA2	SRPRB-1	ARF4-1	PWP1	DHX57	ARFIP1	CIAO2A	HOXA7	POGLUT3	RARS1	ANXA2	TPM3	FNDC3B	FBXW11	FNDC3A	GOLGA7-1	DHX40	IDH1	RAB34	RAI14	SRSF9	TMED10	CBFB	ADIPOR2	MRPL20	COMMD9	ANPEP	SLC38A2	ATP6V1C1	ATP6V1F	PEDS1-UBE2V1;PEDS1	SLC4A10	TBCA	MOV10	NCL-1	HNRNPM	CHMP2A	ANP32B	PICALM	TRAM1	ADAR	MAGT1	MRC2	SPTLC1	GFPT1	SH3BGRL3	TMED7	POLD2	TMED2-1	ELOVL5	ATRX	SIGMAR1	PRPF40A	CTDSP1	CSDE1	POM121;POM121C	PXDN	PTMA	PNP-1	MTPN	SEC23A	TGFBR2	MRPS33	AKAP8	DNAJB1	POLR2C	PPP1R7	SH3BP4	RTN4	PDLIM7	MPZL1	SLC12A2	GALNT7	TXNRD1	GALNT1	AP3D1	ARCN1	CUL4B	TMEM59	SPCS3	FMNL2	GYS1	ATP6V0E2;ATP6V0E1	NEDD4	PDCD4	LAMTOR5	ATP2A2	BET1	SYNE2	TMEM43	HMOX1	TPM1	HES1	E2F3	HSD17B12	LAMC1	SMAD1	P4HA2	NF2	MET	AXL	PISD	THBS1	
ANGIOTENSIN II RECEPTOR TYPE 1 PATHWAY%WIKIPATHWAYS_20260910%WP5036%HOMO SAPIENS	Angiotensin II receptor type 1 pathway	RACK1	PDGFD	COL1A1	HIF1A	COL1A2	IL11RA	CCN2	PTPN11	AGT	RRAS	MAS1	MAP2K6	SMAD4	F12	IL6ST	TGFBR1-1	JUND	SMAD2;SMAD3	RAF1	SP1	IL11	ACE2	AGTR1	ACTA2	TGFB1	NOX4	MAPK1	TGFBR2	
FAMILIAL HYPERLIPIDEMIA TYPE 2%WIKIPATHWAYS_20260910%WP5109%HOMO SAPIENS	Familial hyperlipidemia type 2	APOA4	LIPC	PLTP	GPIHBP1	GHR	EPHX2	PCSK9	APOA1	LDLRAP1	USF1	CETP	APOA2	APOB	LPL	LDLR	LCAT	
PROXIMAL TUBULE TRANSPORT%WIKIPATHWAYS_20260910%WP4917%HOMO SAPIENS	Proximal tubule transport	ABCG2	SLC5A5	SLC6A19	SLC16A10	ATP6V0E2;ATP6V0E1	SLC4A2	SLC4A4	AQP1	CA2	CA4	ATP6V1E1	SLC22A11	SLC13A3	ATP6V1G1	ATP6V0B	SLC6A18	SLC36A2	SLC34A1	ATP1B1	SLC5A8	SLC7A8	SLC7A9	ATP6V0D2	ATP6V0C	ATP6V1B1	ATP6V1A	SLC22A6	SLC47A1	SLC20A2	SLC22A2	SLC1A1	SLC3A1	SLC3A2	ATP1A1	SLC5A2	SLC6A20	CLTRN	ATP6V1H	ATP6V0A4	ATP6V1D	SLC12A4	FXYD2;FXYD6-FXYD2	SLC22A8	ABCB1	SLC22A7	SLC2A1	SLC26A6	SLC2A2	ABCC4	ABCC2	SLC9A3	SLC5A1-1	ATP6V1C1	ATP6V1F	SLC7A7	
OVERLAP BETWEEN SIGNAL TRANSDUCTION PATHWAYS CONTRIBUTING TO LMNA LAMINOPATHIES%WIKIPATHWAYS_20260910%WP4879%HOMO SAPIENS	Overlap between signal transduction pathways contributing to LMNA laminopathies	JUNB	CREBBP	WNT7B	CTNNB1	RB1	CDKN1A	FNTA	CEBPA	CEBPB	TCF7	SPP1	EMD	TMPO	LEMD3	CEBPD	ACTB-1	AXIN1	LEF1	MAOA	E2F1	HES1	HES5	TCF7L2	TCF7L1	CSNK1A1	CTSK	APC	TLE1	DICER1	RUNX2	BMP2	HMGA2	MAOB	TARBP2	AGO2	ICMT	CDK4	LMNA	NOTCH1	ZMPSTE24	SREBF1	WNT10B	TNFRSF11B	SMAD2;SMAD3	KAT2B	MSTN	GSK3B	HDAC1	NAP1L1	TGFB2	MYOD1	TGFB1	PPARG	
HORMONAL CONTROL OF PUBERTAL GROWTH SPURT%WIKIPATHWAYS_20260910%WP4194%HOMO SAPIENS	Hormonal control of pubertal growth spurt	GNRH1	SST	GHRH	IGF1	
OSTEOPONTIN SIGNALING%WIKIPATHWAYS_20260910%WP1434%HOMO SAPIENS	Osteopontin signaling	ITGB3	MAPK3	SPP1	ITGAV	PLAU	IKBKB	CHUK	RELA	MMP9	NFKB1	MAP2K2;MAP2K1	MAPK1	MAP3K14	
MECHANOREGULATION AND PATHOLOGY OF YAP TAZ VIA HIPPO AND NON HIPPO MECHANISMS%WIKIPATHWAYS_20260910%WP4534%HOMO SAPIENS	Mechanoregulation and pathology of YAP TAZ via Hippo and non Hippo mechanisms	ITGB3	ITGB2	MAPK9	ACTC1;ACTG2	SGMS1	LIMD1	MAPK8	ITGB8	STK3	SAV1	ITGB7	YAP1-1	ITGB6	MAP4K5	TEAD1	MAP4K3	WWTR1	TEAD3	MAPK10	MAP4K4	TEAD4	CTNNB1	MAP4K1	MAP4K2	ACTG1	MST1	LATS1	ACTA1	NF2	TEAD2	SRC	BUB1B-PAK6;PAK6	PAK1	CDH1	CTNNA1	PAK5	PAK3	PAK2	PAK4	YWHAQ	ACTB-1	ACTA2	ITGB1	ITGB5	ITGB4	
NEOVASCULARIZATION PROCESSES%WIKIPATHWAYS_20260910%WP4331%HOMO SAPIENS	Neovascularization processes	DLL4	MAPK9	MAPK3	NOTCH3	NOTCH1	MAPK8	NOTCH4	HIF1A	SMAD1	ACVRL1	CXCR4	RELA	CXCL12	JAG1	MMP9	TGFBR1-1	SMAD2;SMAD3	SMAD9	KITLG	SMAD5	KDR	FLT4	PDGFB	EPHB2	AKT1	EPHB4	ANGPT1	REL	RELB	TGFB2	KIT	TGFB1	TGFB3	NFKB1	MAPK1	NFKB2	
MIRNA ROLE IN IMMUNE RESPONSE IN SEPSIS%WIKIPATHWAYS_20260910%WP4329%HOMO SAPIENS	miRNA role in immune response in sepsis	MYD88	TRAF6	MAP3K7	MAPK8	MAPK14	ICAM1	IKBKB	IKBKG	CHUK	IL6	IRF1	RELA	ELANE	GZMH;GZMB-1	TRAF3	CCL3L1;CCL3L3;CCL3;CCL18	NFKBIA	LCN2	IL10	CXCL8	CCL4L2;CCL4L1;CCL4	VCAM1	IL1A	TLR8	TLR7	TLR4	TNF	IRAK1	REL	IRF5	RELB	IRF7	IRAK4	NFKB1	TAB2	NFKB2	TAB1	
JAK STAT SIGNALING AND ARTD FAMILY MEMBERS%WIKIPATHWAYS_20260910%WP5528%HOMO SAPIENS	JAK STAT signaling and ARTD family members	HDAC3	CUL1	HDAC2	STAT1	PARP1	STAT3	BTRC	PARP14	PARP9	STAT6	RBX1	SKP1	DTX3L	PARP11	
PURINERGIC SIGNALING%WIKIPATHWAYS_20260910%WP4900%HOMO SAPIENS	Purinergic signaling	LPAR4	GNAI1	GNA11	LPAR6	GNAS-1	ADORA1	GNAZ	PANX1	P2RY8	P2RY6	GNAT2	P2RY4	GNAT3	P2RY2	ADORA3	P2RY1	GNAI3	GNAT1	GNAI2	P2RY12	P2RY13	P2RY10	P2RY11	P2RY14	ADORA2A	P2RX7	P2RX6	GNAO1	P2RX5	P2RX4	P2RX3	ADORA2B	P2RX2	P2RX1	
NOVEL INTRACELLULAR COMPONENTS OF RIG I LIKE RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP3865%HOMO SAPIENS	Novel intracellular components of RIG I like receptor pathway	SIKE1	CXCL10	RNF125	TRAF6	MAP3K7	IRF3	IFNE	MAPK9	IFNK	NFKBIB	NLRX1	TKFC	DDX3X-1	CYLD	MAVS	SNW1	MAPK14	STING1	MAPK12	PIN1	MAPK13	TBKBP1	IKBKB	ISG15	MAPK10	MAPK11	IKBKG	CHUK	RELA	TRAF2	NFKBIA	CXCL8	IFNG	TNF	IFNB1-4	TANK	IRF7	ATG12-1	ATG5	MAPK8	CASP8	TRADD	RIPK1	FADD	CXCL12	MAP3K1	TRAF3	IFIH1	TBK1	OTUD5	CASP10	DHX58	TRIM25	AZI2	IKBKE	NFKB1	DDX17	DDX58	
INHIBITION OF GNAQ REGULATED SIGNALING IN UVEAL MELANOMA%WIKIPATHWAYS_20260910%WP5490%HOMO SAPIENS	Inhibition of GNAQ regulated signaling in uveal melanoma	PIK3R3	YAP1-1	TEAD1	PLCB3	PKN3	TEAD3	MOB1A;MOB1B	PLCB4	TEAD4	LATS2	RHOA	PKN2	GNAQ	PKN1	PLCB1	LATS1	PLCB2	TEAD2	TRIO	ROCK1	TSC2	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	MTOR	TSC1	PIK3R2	PIK3R1	PTK2	PIK3CA	MAPK1	
CANONICAL AND NON CANONICAL TGF B SIGNALING%WIKIPATHWAYS_20260910%WP3874%HOMO SAPIENS	Canonical and non canonical TGF B signaling	SMAD2;SMAD3	MAPK9	LOXL2	MAPK8	BMPR1A	LOXL4	MAPK14	BMPR2	LOXL1	LOX	BMP1	SMAD4	TGFB1	GREM1	TGFBR1-1	TGFBR2	
INTEGRATIVE ANALYSIS OF TREG GLIAL INTERACTIONS %WIKIPATHWAYS_20260910%WP5561%HOMO SAPIENS	Integrative Analysis of Treg Glial Interactions	ITGB3	ITGAV	HTR7	MAPK14	JAK3	ITGA2	IKZF2	LGALS3	LGALS1	CCN3	ROS1	TGM2	NKX6-2	STAT5A	STAT5B	EBI3	FOXO4	APOD	GSDMD	AREG	MCAM	CDC42	TMEM119	HEXB	CCR8	CCR6	SSTR2	FAM20C	CD47	CX3CR1	CNP	SEMA3F	AIF1	CCL1	KLRG1	TNF	IL33	CCL20	IL10RB	GALC	MBP	CD68	IL1RAP	SOX9	CD4	NKX2-2	MOG	CXCL2;CXCL3;CXCL1-1	OLIG1	IGF1	OLIG2	MYD88	IL1B	PLP1	FOXO1-1	TGFBR1-1	TNFRSF1B	CD86	CD274	CD80	IL2RG	CTLA4	TGFB2	TGFB1	SOCS3	NFKB1	IL10RA	NFKB2	SIRPA;SIRPB1;SIRPG	RAC1	TGFBR2	IL2RA	IL2RB	PDCD1	JAK1	STAT1	STAT3	TYK2	IL6	IGF1R	MMP9	IL10	OSM	PDGFA	IL18	NOS2	IL2	IL4	SPP1	IFNG	PDGFRA	IL12A	TLR4	EGFR	CASP1	NLRP3	VEGFA	CD28	CD44	CXCL12	STAT4	SMAD2;SMAD3	IL12RB1	IL12RB2	FOXP3	P2RY12	FOXO3	TGFBR3	NKX6-1	CSPG4	PTK2	
FIBROTIC RESPONSE OF TRABECULAR MESHWORK CELLS TO TGFB3 AND ENPP2 IN AQUEOUS HUMOR%WIKIPATHWAYS_20260910%WP5545%HOMO SAPIENS	Fibrotic response of trabecular meshwork cells to TGFB3 and ENPP2 in aqueous humor	SMAD2;SMAD3	RHO	MAPK9	COL1A1	MAPK8	STAT3	MAPK10	CCN2	ENPP2	ACTA2	TGFB2	TGFB1	TGFB3	FN1	
WNT SIGNALING%WIKIPATHWAYS_20260910%WP428%HOMO SAPIENS	Wnt signaling	MAPK9	WNT11	WNT7B	CTNNB1	CCND3	CCND2	ROCK2	FOSL1	CCND1	MYC	DKK2	DKK4	PPP3R1	SOX17	CER1	SERPINF1	CTNNBIP1	SFRP1	SFRP2	DAAM1	DAAM2	SFRP5	CTBP2	CTBP1	PORCN	VANGL1	RYK-1	VANGL2	INVS	KREMEN1	ROR1	SENP2	ROR2	PRICKLE2	PRICKLE1	PPP3CA	CXXC4	PPP3CB	NKD1	NKD2	PPP3CC	WIF1	MAPK8	GPC4	NOTUM	PLCB3	PLCB4	PLCB1	PLCB2	JUN	FZD1	FZD3	WNT3A	WNT5A	WNT7A	WNT3	LRP6	GSK3B	NLK	RAC1	MAP3K7	DKK1	SOST	PLAU	TPTEP2-CSNK1E;CSNK1E	FRAT2	CSNK2A2	SFRP4	CSNK2B	TCF7	DVL1	DVL2	DVL3	FZD10	AXIN1	CSNK2A1;CSNK2A3	LEF1	PRKCG	NFATC3	TCF7L2	NFATC4	TCF7L1	WNT5B	CSNK1A1	PRKCB	APC	PRKCA	CAMK2B	CAMK2D	CAMK2A	WNT6	WNT1	NFATC2	CAMK2G	WNT2	RHOA	WNT4	WNT10B	WNT10A	FZD2	FZD5	FZD7	FZD6	FZD9	FZD8	NFATC1	CHD8	WNT2B	WNT16	LRP5	
CHOLESTEROL BIOSYNTHESIS PATHWAY IN HEPATOCYTES%WIKIPATHWAYS_20260910%WP5329%HOMO SAPIENS	Cholesterol biosynthesis pathway in hepatocytes	NR1H3	CYP7A1	IDI1	EBP	CYP51A1	MVK	NSDHL	IDI2	SC5D	MSMO1	DHCR24	HSD17B7	ACAT2	LBR	TM7SF2	HMGCS1-1	PMVK	SREBF1	ACOT2;ACOT1	FDFT1	MYLIP	FDPS	GGPS1	NR1H2	ELOVL3	ACSL3	LSS	PLPP6	CH25H	ABCG1	ABCA1	HMGCS2	CYP46A1	FADS2	ACSL1	SCD	ELOVL4	MVD	HMGCR	ELOVL2	ELOVL5	CYP27A1	
OXIDATIVE PHOSPHORYLATION%WIKIPATHWAYS_20260910%WP623%HOMO SAPIENS	Oxidative phosphorylation	NDUFA9	DMAC2L	ATP5PF	NDUFA8	NDUFA7	NDUFA6	ATP5PD	NDUFA5	NDUFA4	ATP5PB	NDUFA3	ATP5F1D	NDUFAB1	ATP5PO	NDUFS5-1	GZMH;GZMB-1	NDUFA11	NDUFA10	ATP6AP1	ATP6AP2	NDUFC1	NDUFS8	NDUFS7	NDUFS6	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB10	NDUFB6	NDUFB5	NDUFB4	NDUFA4L2	NDUFB2	ATP5MC2	NDUFB1	ATP5MC3	ATP5MC1	ATP5F1A	ATP5F1B	NDUFC2;NDUFC2-KCTD14	NDUFV3	NDUFV2	ATP5MG	NDUFV1	ATP5ME	
COLCHICINE METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP2536%HOMO SAPIENS	Colchicine metabolic pathway	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
CEREBRAL ORGANIC ACIDURIAS INCLUDING DISEASES%WIKIPATHWAYS_20260910%WP4519%HOMO SAPIENS	Cerebral organic acidurias including diseases	IDH2	D2HGDH	MDH2	L2HGDH	ADHFE1	ALDH7A1	ACY1;ABHD14A-ACY1	GCDH	
DRUG INDUCTION OF BILE ACID PATHWAY%WIKIPATHWAYS_20260910%WP2289%HOMO SAPIENS	Drug induction of bile acid pathway	SLC51A	SLC51B	CYP7A1	VDR	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	ABCC3	ABCC4	SLC10A1	ABCC2	NR1I3	NR1I2	NR1H4	BAAT	ABCB11	SULT2A1-4	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	ABCB1	
IL5 SIGNALING%WIKIPATHWAYS_20260910%WP127%HOMO SAPIENS	IL5 signaling	JAK2	RPS6KB2	MAPK3	JAK1	STAT1	STAT3	ELK1	PTPN11	RPS6KA1	MAPT	RPS6KB1	KRAS	GRB2	IL5RA	CSF2RB	JUN	LYN	SOS1	STAT5A	STAT5B	SYK	BTK	SHC1-1	SPRED1	RAF1	IL2	FOXO3	AKT1	PIK3CG	GSK3B	PIK3R2	RPS6	PIK3R1	GSK3A	MAP2K2;MAP2K1	MAPK1	
ACQUIRED PARTIAL LIPODYSTROPHY BARRAQUER SIMONS SYNDROME%WIKIPATHWAYS_20260910%WP5104%HOMO SAPIENS	Acquired partial lipodystrophy Barraquer Simons syndrome	C3-1	LMNB1	FNTA	ICMT	LMNA	C5	LMNB2	RCE1	CFB	CFD	
GLIAL CELL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP2276%HOMO SAPIENS	Glial cell differentiation	MSN	MBP	MAG	TPPP	PLP1	CNP	GAP43	
ALSTROM SYNDROME%WIKIPATHWAYS_20260910%WP5202%HOMO SAPIENS	Alstrom syndrome	DNM3	SMO	VCP-1	RABL2A;RABL2B	TFDP2	PTCH1	ACTN4	E2F4-1	IFT172	BLOC1S4	VCPIP1	HSPB11	IFT74	BLOC1S6	BLOC1S1	STX5	CEP192	SNAPIN	PIFO	IFT81	RFX2	IFT27	DTNBP1	RFX3	RFX1	TUBG1	ARMCX5-GPRASP2;GPRASP2	NSFL1C	CEP19	RILPL1	MYO5B	GPR161	ALMS1	
CARDIAC PROGENITOR DIFFERENTIATION%WIKIPATHWAYS_20260910%WP2406%HOMO SAPIENS	Cardiac progenitor differentiation	DKK1	MAPK14	GATA4	KDR	PDGFRA	FGF2	SOX17	PAX6	MESP2	MESP1	MYLK3	KIT	SCN5A	MEF2C	NRG1	SOX1	ISL1	IGF1	TNNT2	MYL2	ZFP42	MYH6	BMP4	POU5F1;POU5F1B	ROR2	THY1	TBXT	TBX20	TNNI3	ACTC1;ACTG2	NKX2-5	NOTCH1	IRX4	IGF2	TBX5	LIN28B	NANOG;NANOGP8	LIN28A	MIXL1	NODAL	SOX2	BMP1	CXCR4	INS;INS-IGF2	ANPEP	FOXA2	WNT3A	NOG	INHBA	GSK3B	NCAM1	TGFB1	SIRPA;SIRPB1;SIRPG	
NAD METABOLISM SIRTUINS AND AGING%WIKIPATHWAYS_20260910%WP3630%HOMO SAPIENS	NAD metabolism sirtuins and aging	SIRT1	SIRT3	NAMPT	FOXO1-1	HIF1A	ROS1	PPARG	PARP1	FOXO3	NFKB1	TFAM-1	
RALA DOWNSTREAM REGULATED GENES%WIKIPATHWAYS_20260910%WP2290%HOMO SAPIENS	RalA downstream regulated genes	CDC42	EXOC8	RALBP1-1	RALA-1	YBX3	EXOC2	KRAS	RAC3	NRAS	HRAS	RAC1	
PRIMARY FOCAL SEGMENTAL GLOMERULOSCLEROSIS FSGS %WIKIPATHWAYS_20260910%WP2572%HOMO SAPIENS	Primary focal segmental glomerulosclerosis FSGS	ITGB3	ILK	DKK1	ITGAV	PODXL	ITGA3	CTNNB1	CDKN1A	CDKN1B	CDH2	CDKN1C	PLAUR	DAG1	ACTN4	VIM	TLR4	COL4A4	YWHAQ	CR1L;CR1	PAX2	VTN	DNM1	CAMK2B	NPHS1	NOTCH1	NPHS2	WT1	MME	PLCG1	WNT1	SCARB2	SMARCAL1	PTPRO	MKI67	CLDN1	LAMA5	JAG1	SYNPO	NCK1	KIRREL3	CTSV;CTSL	TRPC6	KIRREL2	KRT8	CD2AP	INF2	COL4A3	COL4A5	MYH9	IRF6	LMX1B	UTRN	CD151	LAMB2	PARVA	FYN	MYO1E	LRP6	LIMS4;LIMS1	TLN1	FAT1	VCL	AGRN	AKT1	CD80	PCNA	PLCE1	PTK2	TGFB1	ITGB1	LRP5	ITGB4	
MRNA PROCESSING%WIKIPATHWAYS_20260910%WP411%HOMO SAPIENS	mRNA processing	XRN2	SRSF2	SRSF3	CD2BP2	SNRPF	SREK1	SRSF5	SRSF6	HNRNPU	SRSF7	SNRPA	SNRPB	DHX8	CSTF3	DDX1	CSTF2	SNU13	METTL3	PRPF8	PCBP2	DHX38	SNRPE-2	CPSF4	CPSF1	FUS	DHX9	CPSF3	CLK4	CLK3	LSM2	CLK2	SRPK1	HNRNPL	CLK1	LSM7	HNRNPK	RNPS1	CLASRP	HNRNPC	HNRNPD	SUGP2	SUGP1	SMC1A	CELF1	CELF2	CELF4	SRP54	YBX1	PTBP1	SNRNP70	DHX15	DHX16	RBM5	CPSF2-1	RBM17	PRMT2	PRMT1	PTBP2	PRPF18	HNRNPH1	HNRNPH2	SNRPA1	DNAJC8	HNRNPA1-1	SF3B4	SF3B5	SF3B2	SF3B3	SFSWAP	RNMT	SRSF1	DDX20	CSTF2T	PPM1G	NXF1	POLR2A	U2AF2	TRA2B	SPOP	SNRPB2	SNRPG-2	SF3B1	SRSF10	SF3A3	RBM39	SF3A1	SRSF4-1	RNGTT	SF3A2	HNRNPAB	NUDT21	SNRNP40	PHF5A	HNRNPA2B1	PABPN1-1	SRSF9	RBMX	TMED10	HNRNPM	NONO	PRPF40A	SFPQ-1	SUPT5H	NCBP1	DICER1	NCBP2-1	U2AF1L5;U2AF1	HNRNPR	EFTUD2	SNRPD2	CLP1	SNRPD1	PAPOLA	SNRPD3	SRPK2	TXNL4A	PSKH1	SNRPN	PRPF4B	CDC40	SRRM1	PRPF4	PRPF6	PRPF3	
ENTEROCYTE CHOLESTEROL METABOLISM%WIKIPATHWAYS_20260910%WP5333%HOMO SAPIENS	Enterocyte cholesterol metabolism	APOA4	IDI1	EBP	CD36	CYP51A1	MVK	NSDHL	SC5D	MSMO1	DHCR24	HSD17B7	DHCR7	ACAT2	LBR	TM7SF2	HMGCS1-1	PMVK	FDFT1	APOA1	MTTP	FDPS	SAR1B	LSS	NPC1L1	MGAT1	APOB	LDLR	ABCG8	ABCA1	ABCG5	FABP2	SQLE	SLC27A4	DGAT1	MVD	HMGCR	
STEROL REGULATORY ELEMENT BINDING PROTEINS SREBP SIGNALING%WIKIPATHWAYS_20260910%WP1982%HOMO SAPIENS	Sterol regulatory element binding proteins SREBP signaling	SCARB1	PRKAA1	FGF21	PRKAA2	PRKAG1	PRKAG2	PRKAG3	LDLR	PRKAB2	PRKAB1	ACLY	SP1	CREB1	ATF6	GSK3A	IDI1	CYP51A1	SIRT1	HMGCS1-1	SREBF1	FDFT1	FDPS	NR1H2	ACACA	LPIN1	INS;INS-IGF2	LSS	SAR1B	FASN	GPAM	PPARGC1B	SQLE	MED15	YY1	SEC13	PRKACA-1	SREBF2	RBP4	KPNB1	SCD	SAR1A	INSIG2	INSIG1	RNF139	SCAP	ACSS1	SEC23B	AKT1	SEC31B	MVD	SEC31A	MTOR	CAMP	HMGCR	MBTPS1	SEC24B	SEC24A	MDH1	AMFR	SEC24D-1	CDK8	NFYA-1	PIK3CA	SEC24C	MBTPS2	PPARG	SEC23A	LPL	
TYPE II DIABETES MELLITUS%WIKIPATHWAYS_20260910%WP1584%HOMO SAPIENS	Type II diabetes mellitus	SLC2A4	INSR	CACNA1A	MAPK8	SLC2A2	PRKCZ	TNF	PIK3R5	IKBKB	MAFA	MTOR	GK	IRS1	ADIPOQ	INS;INS-IGF2	SURF1	KCNJ11	PDX1	PHKA2	MAPK1	SOCS4	
BIOTIN METABOLISM INCLUDING IMDS%WIKIPATHWAYS_20260910%WP5031%HOMO SAPIENS	Biotin metabolism including IMDs	PC	HLCS	PCCB	MCCC2	MCCC1	ACACA	ACACB	BTD	PCCA	
ERBB SIGNALING%WIKIPATHWAYS_20260910%WP673%HOMO SAPIENS	ErbB signaling	EIF4EBP1	CBLB	NCK2	MAPK9	NRG2	MAPK3	EREG	BTC	MAP2K4	NRG3	NRG4	PLCG2	HBEGF	ERBB3	BAD	ERBB4	ABL2	ELK1	GAB1	PDPK1	MAPK10	CDKN1A	CDKN1B	RPS6KB1	CBL	GRB2	SOS1	CRK	STAT5A	STAT5B	SHC4	EGF	SHC1-1	SHC2	AREG	SRC	CCND1	TGFA	PAK1	MYC	ERBB2	PAK3	PAK2	PAK4	TP53	MDM2-2	SOS2	EGFR	ABL1	PRKCG	NRG1	PRKCB	PRKCA	RPS6KB2	CAMK2B	CAMK2D	NRAS	MAPK8	CAMK2A	PIK3R3	HRAS	CAMK2G	MAP2K7	KRAS	FOXO1-1	JUN	NCK1	CRKL	BUB1B-PAK6;PAK6	RAF1	ARAF	PAK5	PIK3CD	AKT2	BCL2L11	AKT3	PIK3CB	AKT1	SHC3	MTOR	GSK3B	PIK3R2	BRAF	PIK3CA	PIK3R1	PTK2	MAP2K2;MAP2K1	MAPK1	
MAPK SIGNALING AND ARTD FAMILY MEMBERS%WIKIPATHWAYS_20260910%WP5530%HOMO SAPIENS	MAPK signaling and ARTD family members	MAP3K7	MAPK9	MAPK3	MAP2K4	MAPK8	MAPK14	PARP1	MAPK12	TNKS	MAPK13	MAP3K21	MAPK10	DUSP1	PARP14	MAPK11	MAP3K12	MAP3K9	MAP2K7	MAP2K6	MAP2K3	MAP3K1	MAP3K10	RAF1	MAP3K11	ARAF	ATF4	MAP3K5	MAP3K8	BRAF	MAP2K2;MAP2K1	MAPK1	
SCFA AND SKELETAL MUSCLE SUBSTRATE METABOLISM%WIKIPATHWAYS_20260910%WP4030%HOMO SAPIENS	SCFA and skeletal muscle substrate metabolism	SLC2A4	PYY	GCG	FFAR2	FFAR3;GPR42	PPARD	
ANTIVIRAL AND ANTI INFLAMMATORY EFFECTS OF NRF2 ON SARS COV 2 PATHWAY%WIKIPATHWAYS_20260910%WP5113%HOMO SAPIENS	Antiviral and anti inflammatory effects of Nrf2 on SARS CoV 2 pathway	IRF3	IL1B	RXRA	GUCY1B1	IKBKB	MMP1	KEAP1	IKBKG	CHUK	SLC7A11	IL6	GUCY1A2	GUCY1A1	RELA	MMP3	NFKBIA	GCLC	CXCL8	GSTA3;GSTA5;GSTA1;GSTA2	TMPRSS2	GCLM	HMOX1	NQO1	IL12A	PRKG2	TNF	NFE2L2	CCL13;CCL2	ACE2	NFKB1	NOX1	
ALZHEIMER 39 S DISEASE%WIKIPATHWAYS_20260910%WP5124%HOMO SAPIENS	Alzheimer 39 s disease	ITPR2	GAPDH-1	HSD17B10	IKBKB	CHUK	RELA	APP	CALML6	CALML3	CALML4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD2	PSMD3	PSMD1	ATG14	PSMC2-1	ATG13	DKK2	DKK4	VDAC3	ULK2	ULK1	VDAC1	ATF6	TNF	ATF4	APH1A	NCSTN	GRIN2A	PPP3R1	AXIN2	APH1B	NRBF2	XBP1	EIF2AK3	EIF2AK2	GRIN2C	GRIN2B	GRIN2D	ATG2A	NOX4	CALM1	CALM2	NOX1	ATG2B	IDE	SLC25A4	RYR3	TUBA1C	IL1B	PPP3CA	PPP3CB	TUBA1A	PPP3CC	PSENEN	MAPK8	MME	BACE1	CASP8	PSMA5	PSMA6	PLCB3	PSMA3	PLCB4	FADD	PSMA4	PSMA1	MAPT	TNFRSF1A	PLCB1	PLCB2	MAP2K7	TUBB3;TUBB6	PSMA7	PSMA8	PSMB6	PSMB7	PSMB4	PSMB5	DDIT3	PSMB2	PSMB3	PSMB1	APBB1	TUBB4B	RAF1	CALM3;CALM1	GRIN1	FZD1	PSMA2-1	PSMC5	FZD3	PSMC6	PSMC3	WNT3A	PSMC4	WNT5A	WNT7A	PSMC1	CDK5R1	IRS4	VDAC2-1	WNT3	KIF5C	LRP6	AKT2	KIF5B	AKT3	KIF5A	AKT1	TUBB1	MAP3K5	MTOR	CYBB	TUBA4A	ERN1	ADAM17	PPIF	PPID	GSK3B	RTN3	PIK3R2	PSMD12	PIK3R1	PSMD14	PSMD13	PSEN2	ITPR1	MAP2K2;MAP2K1	CACNA1D	GPR83	MAPK1	ITPR3	CACNA1C	PSEN1	CACNA1F	KLC1	AGER	MAPK3	DKK1	RTN4	KLC4	KLC3	KLC2	ATG101	NAE1	BAD	CACNA1S	TUBA3E;TUBA3C-1	EIF2S1	SEM1	TUBB4A;TUBB;TUBB8B;TUBB8	TPTEP2-CSNK1E;CSNK1E	MCU	TUBA8	ATP2A3	IL6	ATP2A2	ATP2A1	FRAT2	RB1CC1	TUBB2B;TUBB2A	TRAF2	CSNK2A2	WIPI1	SFRP4	WIPI2	CSNK2B	SLC25A5	SLC25A6	BECN1	TUBAL3	DVL1	BECN2	DVL2	AMBRA1	SNCA	DVL3	NOS2	ADRM1	SLC25A31	IL1A	FZD10	APC2	AXIN1	CSNK2A1;CSNK2A3	CSNK1A1	WNT5B	APC	PIK3R4	PIK3R3	WNT6	WNT1	WNT2	WNT4	WNT10B	WNT10A	FZD2	FZD5	FZD7	FZD6	FZD9	FZD8	ARAF	CAPN2	CAPN1	WNT2B	PIK3CD	PIK3CB	BRAF	WNT16	PIK3CA	PIK3C3	LRP5	MAPK9	WNT11	WNT7B	MAPK10	CTNNB1	CASP9	CASP3	APAF1	CYCS-1	BID	CDK5	FAS	IRS1	IRS2	INS;INS-IGF2	CHRNA7;CHRFAM7A	NOS1	NFKB1	APOE	INSR	CSF1	CASP7	ADAM10	NRAS	HRAS	GNAQ	KRAS	PTGS2-2	LRP1	LPL	
NONALCOHOLIC FATTY LIVER DISEASE%WIKIPATHWAYS_20260910%WP4396%HOMO SAPIENS	Nonalcoholic fatty liver disease	MAPK9	PRKAA1	RXRA	IKBKB	UQCRB	UQCR11	CEBPA	UQCR10	BBC3	RELA	UQCRQ	PRKAA2	UQCRC1	PRKAG1	PRKAG2	UQCRFS1	CYC1	UQCRC2	PRKAG3	CASP3	CDC42	PRKAB2	PRKAB1	VCAM1	TNF	ATF4	CYCS-1	PPARA	XBP1	EIF2AK3	BID	GSK3A	IL1B	NR1H3	MAPK8	CASP8	FAS	BAX	SREBF1	TNFRSF1A	IRS1	IRS2	ADIPOQ	LEPR	JUN	INS;INS-IGF2	ADIPOR1	DDIT3	ADIPOR2	NDUFA11	NDUFA10	NDUFA13	MAP3K11	NDUFC1	NDUFS8	NDUFS7	NDUFS6	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	AKT2	NDUFB7	AKT3	NDUFB10	AKT1	NDUFB6	MAP3K5	NDUFB5	CCL13;CCL2	NDUFB4	NDUFA4L2	ERN1	NDUFB2	NDUFB1	GSK3B	CYP2E1	PIK3R2	PIK3R1	NDUFC2;NDUFC2-KCTD14	TGFB1	NDUFV3	SOCS3	NDUFV2	NFKB1	NDUFV1	RAC1	NDUFA9	IL6R	NDUFA8	NDUFA7	NDUFA6	NDUFA5	NDUFA4	NDUFA3	NDUFAB1	EIF2S1	NDUFS5-1	LEP	NDUFA12	IL6	COX6A1	COX6A2	NR1H4	SDHC	SDHD	TRAF2	SDHA	COX6B2	SDHB	COX6B1	NDUFB11	COX7A2	COX7B2	CXCL8	COX7B	COX4I1	INSR	COX4I2	COX7C	MLX	COX8A	COX8C	IL1A	COX7A2L-1	NDUFB3	COX5B	COX5A	MLXIP	SMAD7	PKLR	COX6C	ITCH	CASP7	BAK1	PIK3R3	BCL2L11	PIK3CD	PIK3CB	FASLG	PIK3CA	
JAK STAT SIGNALING IN THE REGULATION OF BETA CELLS%WIKIPATHWAYS_20260910%WP5358%HOMO SAPIENS	JAK STAT signaling in the regulation of beta cells	SOCS2	JAK2	IL6R	CDK4	NRAS	STAT1	HRAS	STAT3	GHR	IL6	KRAS	CCND3	CCND2	STAT5A	STAT5B	EPO	RPTOR	IFNGR1	IFNGR2	IFNG	MLST8	AKT2	EPOR	AKT3	AKT1	MTOR	PRL	SOCS1	CISH	PRLR	FOXM1	SOCS3	AKT1S1	
ERK PATHWAY IN HUNTINGTON 39 S DISEASE%WIKIPATHWAYS_20260910%WP3853%HOMO SAPIENS	ERK pathway in Huntington 39 s disease	RAF1	MAPK3	CREB1	RPS6KA5	GRM1	HRAS	ELK1	HTT	EGFR	CASP7	NTRK2	BDNF	EGF	MAP2K2;MAP2K1	CASP3	MAPK1	
ASPIRIN PREVENTION OF CANCER METASTASIS%WIKIPATHWAYS_20260910%WP5518%HOMO SAPIENS	Aspirin prevention of cancer metastasis	GNA13	GNA12	RHOA	ARHGEF1	TBXAS1	TBXA2R	PTGS1	
NIFEDIPINE ACTIVITY%WIKIPATHWAYS_20260910%WP259%HOMO SAPIENS	Nifedipine activity	PTK2B	PCNA	SOD1	KDR	BDKRB2	MAP2K2;MAP2K1	MAPK1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
IMATINIB AND CHRONIC MYELOID LEUKEMIA%WIKIPATHWAYS_20260910%WP3640%HOMO SAPIENS	Imatinib and chronic myeloid leukemia	MYC	ABCG2	PDGFRA	PDGFRB	FOXO3	CSF1R	GAB2	CDKN1B	NOP2	BCR	ABL1	SPRED2	PIM2	KIT	SKP2	FLT1	PIM1	GADD45A	ABCB1	LYL1	
MITOCHONDRIAL LONG CHAIN FATTY ACID BETA OXIDATION%WIKIPATHWAYS_20260910%WP368%HOMO SAPIENS	Mitochondrial long chain fatty acid beta oxidation	ACADM	HADH	ACADS	EHHADH-1	ACSL1	SCP2	CPT1A	PECR	ACADVL	ECI1	ACSL3	ACSL4	ACSF2	HADHA	ACADL	CPT2	SLC25A20	
FAMILIAL HYPERLIPIDEMIA TYPE 5%WIKIPATHWAYS_20260910%WP5112%HOMO SAPIENS	Familial hyperlipidemia type 5	APOA4	APOA5	LMF1	LIPC	APOC2	PLTP	GPIHBP1	APOA1	CETP	LRP1	SEL1L	APOA2	LPL	LDLR	LCAT	
CLOCK CONTROLLED AUTOPHAGY IN BONE METABOLISM%WIKIPATHWAYS_20260910%WP5205%HOMO SAPIENS	Clock controlled autophagy in bone metabolism	JAK2	TRAF6	DKK1	SP7	SOST	ATG101	LEP	IL6	RB1CC1	CLOCK	TNFSF11	PRKAA2	CALCA	BECN1	NR1D2	AMBRA1	ATG13	HMGB1-1	BHLHE41	ULK1	LAMP2	IL3	CSF1	SERPINF1	ATG3	MAP1LC3B2;MAP1LC3B-1	ATG10	ARNTL	ATG12-1	SQSTM1	IGF1	ATG7	CTSK	ATG5	BMP4	RUNX2	BMP2	ATG16L1	ARHGAP4	FYCO1	MEPE	ATG4C	NOTCH1	CTF1	PER1	SEMA3A	CHRD	EFNB2	DRAM2	CTHRC1	TRAP1	VCP-1	SEMA4D	RORB	BMP5	BMP3	PLEKHM1	BMP6	WNT10B	SMAD1	SMAD4	BCL2	TNFRSF11B	SMAD9	SMAD5	TNFRSF11A	NPAS2	NFATC1	WNT5A	BMPR2	AKT1	MTOR	MAP1LC3A	BHLHE40	WNT16	PTH	TGFB1	PIK3C3	LRP5	CRY1	
HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CARCINOMA PATHWAY%WIKIPATHWAYS_20260910%WP4206%HOMO SAPIENS	Hereditary leiomyomatosis and renal cell carcinoma pathway	SLC2A1	PDHA1	PRKAB1	LDHA	PRKAA1	HIF1A	PDK1	TP53	NFE2L2	KEAP1	CUL3	SLC11A2	RPS6	VEGFA	PDHB	ACACA	PRKAG1	ACACB	EGLN1	
APOPTOSIS RELATED NETWORK DUE TO ALTERED NOTCH3 IN OVARIAN CANCER%WIKIPATHWAYS_20260910%WP2864%HOMO SAPIENS	Apoptosis related network due to altered Notch3 in ovarian cancer	ERBB3	VAV3	CDKN1A	PKN1	CDKN1B	RPS6KB1	APP	JUND	APOE	CUL1	PAK2	VIM	F2R	SMAD7	TNF	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	AXIN1	HSPD1	PTK2B	ABL1	CASP7	NRG1	SQSTM1	IL7R	YBX3	SERBP1-1	IER3	HELLS	TRAF1	CARD14	TNFRSF21	BEX3	ETS1	CUL5	RNF7	NET1	GCLC	BCL3	CTNNA1	BIRC5	NQO1	ANXA5	RIPK2	AKT1	HSPB1	ERN1	THBS1	HDAC1	HSPA5	PTK2	SOCS3	NFKB1	MAPK1	
22Q11 2 DISTAL CNV%WIKIPATHWAYS_20260910%WP5546%HOMO SAPIENS	22q11 2 distal CNV	UBA6	CUL2	CABP1	AK8	SNRPF	CD79B	CD79A	SDF2L1	CWC15	TDRD3	RPS29	SNRPB	SNW1	RPS20	HYOU1	AQR	RPS21	RPS24	RPS23	ELOC-1	PRPF8	IQUB	ELOB	ARIH1	SNRPE-2	TOP3B	CCDC116	BUD31	NME5	CBL	PLRG1	YDJC	CANX	RBM22	LRP4	RSPH9	PPM1F	RNF113A	CHEK1	RPS15A	RPS3	PAK1	PRAME	RPS2	RILP	UGGT1	PAK2	PPIL2	CDC5L	RSPH3	XAB2	YPEL1	FAU	CAMK1	PPIL4	ATF6	CDC16	PPIL6	DHX16	TP53	MDM2-2	SOX9	XBP1	RBX1	SNRPA1	SF3B4	SF3B5	SF3B2	SF3B3	RPS27A	UBA1	SNRPB2	SNRPG-2	SF3B1	UBE3A	SF3A3	SF3A1	SF3A2	SNRNP40	PHF5A	RPS6	HSPA5	CALR-1	PPIB	MAPK1	DNAJB11	RACK1	NEDD4	PRKN	BCR	HSP90B1	CAMK2A	RNF19B	GNAZ	PPIL1-1	RPS15	RPS14	RPS17	VPREB1	RPS16	PTPA	RPS19	RPS18	CWC22	ROPN1L	RPS11	RPS10	RPS13	CAMK4	RPS12	RSPH6A	SRRM2	PDIA2	EFTUD2	RPS9	SNRPD2	ZNF280D;ZNF280A	RPS7	SNRPD1	RPS8	RPS5	SNRPD3	DNAJB13	RPSA	CRNKL1	PDIA4	IGLL5;IGLL1	RAB36	ERP29	PPIE	DYDC1	SNRNP200	
FABP4 IN OVARIAN CANCER%WIKIPATHWAYS_20260910%WP4400%HOMO SAPIENS	FABP4 in ovarian cancer	FABP4	
RELATIONSHIP BETWEEN INFLAMMATION COX 2 AND EGFR%WIKIPATHWAYS_20260910%WP4483%HOMO SAPIENS	Relationship between inflammation COX 2 and EGFR	PTGER3	CYP19A1	MAPK3	NRAS	HRAS	PLA1A	MMP1	KRAS	PTGS2-2	ESR1	SRC	PIK3CD	AKT2	AKT3	PTGES2	PIK3CB	AKT1	PTGER4	PIK3CG	PTGER2	EGFR	BRAF	PIK3CA	MAPK1	PTGER1	
NAD BIOSYNTHETIC PATHWAYS%WIKIPATHWAYS_20260910%WP3645%HOMO SAPIENS	NAD biosynthetic pathways	IDO1	PARP1	TNKS	SIRT4	PARP4	SIRT5	NADSYN1	SIRT1	BST1	SIRT2	TNKS2	SIRT3	NAPRT	SIRT6	NMNAT1	NAMPT	QPRT	CD38	ACMSD	TDO2	PARP2	
EPAC1 AND PKA REDUCTION OF RETINAL INFLAMMATION%WIKIPATHWAYS_20260910%WP5440%HOMO SAPIENS	EPAC1 and PKA reduction of retinal inflammation	PRKAR2A	IL1B	NEK7	RAPGEF3	PRKAR1B	PRKAR1A	NLRP3	PRKACB-1	
AMINO ACID TRANSPORT DEFECTS IEMS %WIKIPATHWAYS_20260910%WP5029%HOMO SAPIENS	Amino acid transport defects IEMs	SLC1A1	SLC3A1	SLC36A2	SLC3A2	SLC6A20	CLTRN	SLC7A7	SLC7A9	SLC6A19	
HFE EFFECT ON HEPCIDIN PRODUCTION%WIKIPATHWAYS_20260910%WP3924%HOMO SAPIENS	Hfe effect on hepcidin production	BMP6	HFE	HJV	ID1	TMPRSS6	HAMP	SMAD7	
BILE ACID SYNTHESIS AND ENTEROHEPATIC CIRCULATION %WIKIPATHWAYS_20260910%WP4389%HOMO SAPIENS	Bile acid synthesis and enterohepatic circulation	SLC10A1	FGFR4	MAPK3	CYP7A1	ABCB11	FXR1-1	FGF19	SLC10A2	ABCG8	MAPK1	LDLR	ABCG5	
MSMP EXPRESSION REGULATION IN CANCER CELLS AND ITS PRO ANGIOGENIC ROLE IN OVARIAN TUMORS%WIKIPATHWAYS_20260910%WP4397%HOMO SAPIENS	MSMP expression regulation in cancer cells and its pro angiogenic role in ovarian tumors	CCR2	CTCF	MSMP	
SENESCENCE ASSOCIATED SECRETORY PHENOTYPE SASP %WIKIPATHWAYS_20260910%WP3391%HOMO SAPIENS	Senescence associated secretory phenotype SASP	H4C6	UBE2C	MAPK3	MAPK7	STAT3	CDKN1A	CDKN1B	FOS	IL6	UBA52	CDC23	CDC27	RELA	ANAPC7	CCNA1	ANAPC4	ANAPC5	CEBPB	ANAPC1	CXCL8	ANAPC2	ANAPC10	ANAPC11	IL1A	CDKN2D	CDKN2B	CDKN2C	CDC16	CCNA2-1	H2BC21	FZR1	EHMT2	UBE2D1	EHMT1	H2AC14	CDC26	RPS27A	H3-3A	UBB;UBC	H2AC4	CDK6	H2AZ2;H2AZ1	H2AJ	ANAPC15	CDK4	ANAPC16	CDK2	H2BC8;H2BC6;H2BC4;H2BC10;H2BC7	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	H2BC5	H2BC1	H2BC15;H2BC3;H2BC11;H2BC12	UBE2S	H2AC20	H2AB2;H2AB3;H2AB1	RPS6KA3	RPS6KA2	RPS6KA1	JUN	IGFBP7	H4-16	CDKN2A	UBE2E1	NFKB1	MAPK1	H4C1	
ATM SIGNALING%WIKIPATHWAYS_20260910%WP2516%HOMO SAPIENS	ATM signaling	RAD50	MAPK9	RAD51	CDK2	CDK1	ATF2	ATM	MDC1	RIPK1	RAD9A	TP53BP1	IKBKG	CRADD	CDKN1A	MDM4	MRE11	BRCA1	PIDD1	JUN	CHEK2	CHEK1	TLK1	NBN	SMC1A	CDC25C	CDC25A	CREB1	CCNE1	TP53	MDM2-2	TP73	CCNB1	ABL1	CASP2	BID	GADD45A	
POLYOL PATHWAY%WIKIPATHWAYS_20260910%WP690%HOMO SAPIENS	Polyol pathway	KHK	ALDOB	AKR1B1	SORD	
16P13 11 COPY NUMBER VARIATION SYNDROME %WIKIPATHWAYS_20260910%WP5502%HOMO SAPIENS	16p13 11 copy number variation syndrome	ABCC6	DCTN6	PLAG1	DCTN4	ACTR1A	ACTR1B	PLAGL1	KIAA0753	MYH11	BMERB1	DCP2-1	DISC1	OFD1-1	ABCC1	NDE1	MARF1	DCP1A	CEP20	ACTR10	PAFAH1B1	DCTN1	RAPGEF4	PLK1	GATA3	RAP1A	
VITAMIN A AND CAROTENOID METABOLISM%WIKIPATHWAYS_20260910%WP716%HOMO SAPIENS	Vitamin A and carotenoid metabolism	SCARB1	RXRA	CD36	CYP26A1	ADH4	ADH1C;ADH1B;ADH1A	ALDH1A1	RPE65	SDR16C5	RDH12	NPC1L1	RXRB	AWAT2	CYP26B1	ABCG8	ABCG5	LRAT	RXRG	BCO1	RBP4	RARG	CRABP2	RDH8	DGAT1	RETSAT	CRABP1	RLBP1	RDH10	BCO2	DHRS3	ALDH1A3	RBP7	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	RBP2	RBP1	SULT2B1	RARA	RARB	RDH5	ALDH1A2	CYP2E1	LPL	MAPK1	
PRADER WILLI AND ANGELMAN SYNDROME%WIKIPATHWAYS_20260910%WP3998%HOMO SAPIENS	Prader Willi and Angelman syndrome	BBS4	NDC1	NUP214	NUP210	NUP133	NIPA1	TACR3	NIPA2	SNURF	NUP93	NUP50	FEZ1	FEZ2	NUP54	NUP98	OCA2	NUP205	SLC45A2	RB1	SEH1L	NUP58-2	POMC	DLX5	TUBGCP2	FSHB	ATP10A	AAAS	LHB	NUP160	NHLH2	NUP85	NUP42	CCND2	TPR	NDN	NUP43	NUP88	CGA	MSX1	RAE1	CCND1	RANBP2	NUP155	NUP153	TYR	GNRH1	OXT-1	KISS1	TUBGCP5	NUP35	MKRN3	CDC6	TUBGCP6	TUBGCP3	CDKN2B	TUBGCP4	CDKN2C	NUP37	TP53	MDM2-2	GABRB3	E2F1	GABRG3;GABRG2	GABRD	CDK6	CYFIP1	GABRA5	CDK4	RNF8	FMR1	GABRG1	GHRH	GHRL	PRKCZ	UBE3A	MDM4	NGF	EIF4E	UBE2N	BDNF	INS;INS-IGF2	MAGEL2	SEC13	PCSK1	CDKN2A	NUP107	NUP188	SNRPN	POM121;POM121C	AHCTF1	GLE1	GABRR3	GABRR2	GABRR1	HERC2	NUP62	
GLYCOSPHINGOLIPID METABOLISM%WIKIPATHWAYS_20260910%WP5292%HOMO SAPIENS	Glycosphingolipid metabolism	B3GALT2	B3GNT5	B3GALT1	B4GALT3	ARSA	GBA	GALC	GBA2	UGT8	UGCG	NEU3	NEU4	GAL3ST1	ST3GAL5	B4GALNT1	A4GALT	B4GALT6	A3GALT2	GLA	B4GALT4	B4GALT5	
FRAGILE X SYNDROME%WIKIPATHWAYS_20260910%WP4549%HOMO SAPIENS	Fragile X syndrome	CPT1A	RHEB	APP	DAG1	HOMER1	SRC	PRKAR1A	CREB1	CLTC	CAMK1	CLTA	AP2A1	KCND2	GRIN2A	AP2M1	MKNK1	GRIN2B	DNM1	DNM2	AP2B1	ALDH5A1	PPP3CA	GAD1	PPP1CA	ABAT	GRM5	CLTCL1	AP2S1	PLCB1	EIF4E	BDNF	RAF1	SLC6A1	GRIN1	TSC2	FYN	AKT1	MTOR	ITPR1	MAP2K2;MAP2K1	AGAP2	MAPK1	MECP2	GAB1	PTPN11	RPS6KB1	GRB2	MMP9	SOS1	SHC1-1	PTEN	MAP1LC3B2;MAP1LC3B-1	GABRB2	GPHN	GABRG3;GABRG2	GABRD	CYFIP2	EIF4A1	SH3GL3	PRKCA	GABRA1	GRIP1	DICER1	DEPTOR	SH3GL1	CAMK2B	TARBP2	CYFIP1	EPHA4	GRIA1	AGO2	GRIP2	EEF1A1	ALDH3A2	FMR1	TBC1D7;TBC1D7-LOC100130357	HOXB8	PLCG1	CAMK2A	TELO2	GRIA2	RAP1GAP	GRM1	EIF4EBP2	SLC16A1	SYNGAP1	ARHGAP32	NF1	EIF4G1	PPP2R5B	ABCD3	KCNC1	TECR	ARC	CLTB	DLGAP3	DUSP3	SHANK1	KRAS	TTI1	PICK1	DLG4	AKAP5	CNR1	EPS8L1	PTPN5	HCN1	ARAF	RPTOR	PRKACA-1	MLST8	PDK1	CAMK4	MAP1B	PIK3CB	TSC1	NTRK2	CDKN2A	BRAF	AKT1S1	
PAFAH1B1 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5409%HOMO SAPIENS	PAFAH1B1 copy number variation	VLDLR	PAFAH1B3	PAFAH1B2	NDEL1	PAFAH1B1	TUBA1A	CLIP1	DYNC1H1	RELN	NUDC	DCX	
METABOLISM OF DICHLOROETHYLENE BY CYP450%WIKIPATHWAYS_20260910%WP3666%HOMO SAPIENS	Metabolism of dichloroethylene by CYP450	CYP2E1	
GLYCOSYLATION AND RELATED CONGENITAL DEFECTS%WIKIPATHWAYS_20260910%WP4521%HOMO SAPIENS	Glycosylation and related congenital defects	DPAGT1	ALG8	ALG9	B4GALT1	ALG6	TUSC3	MPI	PMM2	SRD5A3	ALG2	MAGT1	ALG14	ALG3	DOLK	MOGS	ALG12	ALG1	ALG11	DPM1	GMPPB	DPM3	MGAT2	MPDU1	DPM2	
JOUBERT SYNDROME%WIKIPATHWAYS_20260910%WP4656%HOMO SAPIENS	Joubert syndrome	TCTN2	BBS4	CSPP1	TCTN1	BBS9	BBS7	CEP97	CEP290	CC2D2A	BBS5	ARMC9	RPGRIP1L	TMEM138	RP2	TMEM216	ANKS6	CEP104	ARL3	ARL2	RAB8A	ARL13B	TMEM67	MRE11	INPP5E	RHEB	NPHP1	MYO6	PDE6D	NPHP3	FLNA	PDE6B	PDE6A	AHI1	PCNT	PIBF1	NEK8	BBS2	DVL1	BBS1	RAB3IP	MYO5A	MKS1	DVL3	CPLANE1	TMEM231	NIN	TTC8	TMEM17	KIAA0586	TMEM237	UNC119	B9D1	CEP41	B9D2	ATF4	SHH	INVS	RAD50	PARP1	ATM	RHOA	CETN2	OFD1-1	MTOR	ZNF423	CETN1	CEP120	CEP164	CCP110	ARR3	KAT5	TCTN3	
ALLOGRAFT REJECTION%WIKIPATHWAYS_20260910%WP2328%HOMO SAPIENS	Allograft rejection	C3-1	IL2RA	C1QC	PRF1	STAT1	IL12B	LOC110384692;C4A;C4B_2;C4B	IL13	CASP9	CSNK2A2	CASP3	IL10	C5	CXCL8	C1QB	IL2	IL4	IL1A	VIM	IFNG	C2	CD40LG	PDGFRA	IL12A	C6	C7	C9	HLA-DPB1-1	TNF	CD55	IL5	CXCL13	C8B	C8A	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	CXCL9	HLA-DOA	LRRK2	HLA-DOB	GABPA	HLA-DPA1	HLA-DRA	BHMT2	CASP7	CXCR5	HLA-DQB2;HLA-DQB1	PECR	HLA-DMB	VEGFA	CCL19	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	CD28	HARS1	CCL21	COL5A1	CXCL11	ABCB1	IL17A	IL1B	GDNF	CASP8	FAS	PRKCZ	IL21	IL22	CXCL12	GZMH;GZMB-1	HLA-DMA	CD40	FOXP3	CD86	CD80	FASLG	AGTR1	CTLA4	TGFB1	
RAC1 PAK1 P38 MMP2 PATHWAY%WIKIPATHWAYS_20260910%WP3303%HOMO SAPIENS	RAC1 PAK1 p38 MMP2 pathway	EIF4EBP1	MAPK9	MAPK3	BAD	MAPK14	STAT3	MAPK12	MAPK13	IKBKB	PTPN11	MAPK11	CTNNB1	IKBKG	CHUK	DOK2	MMP2	RELA	GRB2	CASP9	SOS1	CRK	STAT5A	STAT5B	NFKBIA	FN1	SRC	PAK1	MYC	NOS2	ERBB2	TP53	EGFR	CASP7	MSH2	RS1	TNIP3-2	RASA1	ANGPTL1	GRB14-1	GRB7	RAD51	TIE1	TNIP1	TNIP2	NRAS	MAPK8	YAP1-1	BAX	HRAS	KRAS	FOXO1-1	NCK1	STMN1	NOS1	BIRC5	ANGPT4	AKT1	PXN	ANGPT2	ANGPT1	TEK	PIK3CA	PIK3R1	PTK2	ITGB1	NFKB1	MAPK1	RAC1	
GLYCOSAMINOGLYCAN DEGRADATION%WIKIPATHWAYS_20260910%WP4815%HOMO SAPIENS	Glycosaminoglycan degradation	HEXB	HGSNAT	HPSE2	IDUA	HEXA	GLB1	GNS	SGSH	GALNS	HYAL1	HYAL2	HYAL4	IDS	NAGLU	HPSE	GUSB	ARSB	
IL10 ANTI INFLAMMATORY SIGNALING%WIKIPATHWAYS_20260910%WP4495%HOMO SAPIENS	IL10 anti inflammatory signaling	IL6	BLVRB	JAK1	IL1A	STAT2	HMOX1	BLVRA	STAT1	STAT3	IL10	IL10RA	IL10RB	
NUCLEAR RECEPTORS%WIKIPATHWAYS_20260910%WP170%HOMO SAPIENS	Nuclear receptors	ROR1	NR1H3	RXRA	AR	NR2C2	VDR	PPARD	NR5A1	NR2F6	NR1I3	NR1I2	NR2F2	NR2E1	NR3C1	NR1H2	RORC	ESRRA	RORA	ESRRB	NR2F1	THRB	NR0B1	THRA	RXRB	NR4A2	ESR1	NR4A1	NR1D2	NR5A2	RXRG	HNF4A	ESR2	PGR	RARG	RARA	PPARA	RARB	PPARG	
CALCIUM MEDIATED T CELL APOPTOSIS INVOLVED IN INCLUSION BODY MYOSITIS%WIKIPATHWAYS_20260910%WP5142%HOMO SAPIENS	Calcium mediated T cell apoptosis involved in inclusion body myositis	ITPRIP	CABIN1	LCK	CD8A	HDAC2	PPP3CA	CD8B;CD8B2	PPP3CB	MEF2D	PPP3CC	CAPN2	PLCG1	EP300	NFATC2	CD4	ATP2A1	HDAC1	ZAP70	CALM1	NR4A1	
WNT BETA CATENIN SIGNALING AND ARTD FAMILY MEMBERS%WIKIPATHWAYS_20260910%WP5529%HOMO SAPIENS	Wnt Beta catenin signaling and ARTD family members	DVL2	CUL1	DVL3	TNK2	TNK1	PLK1	PARP10	PARP1	BTRC	CTNNB1	AXIN1	RBX1	SKP1	APC	DVL1	
HIJACK OF UBIQUITINATION BY SARS COV 2%WIKIPATHWAYS_20260910%WP4860%HOMO SAPIENS	Hijack of ubiquitination by SARS CoV 2	CUL2	ELOB	RBX1	ZYG11B	UBA3	NAE1	CBFB	ELOC-1	
DEVELOPMENT AND HETEROGENEITY OF THE ILC FAMILY%WIKIPATHWAYS_20260910%WP3893%HOMO SAPIENS	Development and heterogeneity of the ILC family	IL1B	IL12B	ZBTB16	IL6	IL22	IL13	RORC	RORA	IL25	TBX21	AREG	IL18	IL9	IL4	IFNG	IL23A	ID2-1	IL12A	GFI1	EOMES	TNF	IL33	TSLP	IL5	BCL11B	GATA3	IL15	TOX	HNF1A	IL7	AHR	NFIL3	IL17A	
FAMILIAL HYPERLIPIDEMIA TYPE 4%WIKIPATHWAYS_20260910%WP5111%HOMO SAPIENS	Familial hyperlipidemia type 4	APOA4	APOA5	LMF1	LIPC	APOC2	DGAT2	PLTP	GPIHBP1	FAS	ACSS1	PDIA2	GCK	APOA1	MTTP	CETP	LRP1	SEL1L	GCKR	APOA2	LPL	LDLR	LCAT	
EUKARYOTIC TRANSCRIPTION INITIATION%WIKIPATHWAYS_20260910%WP405%HOMO SAPIENS	Eukaryotic transcription initiation	POLR3B	POLR1A	ILK	POLR2C	ERCC3	POLR3D	POLR1B	POLR3E	POLR1D	POLR2A	TAF7	POLR1E	TAF6	ERCC2	POLR3H	TAF5	POLR3K	CDK7	MNAT1	GTF2H2C;GTF2H2C_2;GTF2H2	GTF2A2	CCNH	GTF2B	TAF9	GTF2E1	GTF2E2	POLR2B	POLR2E	POLR2F	POLR2G	POLR2H	POLR2I	TBP	GTF2H1	TAF12	GTF2H3	TAF13	GTF2F2	GTF2H4	POLR2J;POLR2J2;POLR2J3	
IDO METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP5414%HOMO SAPIENS	IDO metabolic pathway	IDO1	GOT2-1	IFNG	AADAT	KMO	TDO2	KYNU	KYAT3	TNF	KYAT1	IDO2	
TAMOXIFEN METABOLISM%WIKIPATHWAYS_20260910%WP691%HOMO SAPIENS	Tamoxifen metabolism	CYP2A13;CYP2A6;CYP2A7-1	CYP2D6;LOC107987479;LOC107987478-1	FMO1	CYP2C9;CYP2C19	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	CYP1B1	FMO3	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	CYP1A1	CYP2E1	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	SULT2A1-4	
PATHOGENESIS OF SARS COV 2 MEDIATED BY NSP9 NSP10 COMPLEX%WIKIPATHWAYS_20260910%WP4884%HOMO SAPIENS	Pathogenesis of SARS CoV 2 mediated by nsp9 nsp10 complex	LCK	CD8A	CD8B;CD8B2	FYN	CD3G	PRG3	CD3E	CD2	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	NKRF	CD247	CD4	LBP	MMP25	IL6	HLA-DRA	CRP	IGLL5;IGLL1	ZAP70	CXCL8	
KALLMANN SYNDROME%WIKIPATHWAYS_20260910%WP5074%HOMO SAPIENS	Kallmann syndrome	GNRH1	MYRF	FGFR1	CHD7	ASCL1	PROK2	PTPN11	AKT1	PLXND1	FRS2	SEMA3E	ANOS1-1	TMEM98	OTX2	LHB	FGF8	GRB2	NEUROG1	PIK3CA	OLIG2	PROKR2	MAP2K2;MAP2K1	MAPK1	SOX10	
MITOCHONDRIAL FATTY ACID OXIDATION DISORDERS%WIKIPATHWAYS_20260910%WP5123%HOMO SAPIENS	Mitochondrial fatty acid oxidation disorders	ACADM	HADH	ACADS	EHHADH-1	ACSL1	SCP2	CPT1A	PECR	HADHB-1	ACADVL	SLC22A5	ECI1	ACSL3	ACSL4	ACSF2	HADHA	ACADL	CPT2	SLC25A20	
GLYCOSAMINOGLYCAN SYNTHESIS IN FIBROBLASTS%WIKIPATHWAYS_20260910%WP5395%HOMO SAPIENS	Glycosaminoglycan synthesis in fibroblasts	CHST11	CHST12	CHST13	CHST14	HS3ST1	HS3ST2	CHPF	XYLT2	HS2ST1	XYLT1	EXTL2	EXTL1	DSE	CHST15	CHSY3	EXTL3	CSGALNACT1	CHPF2	B3GAT3	HS6ST1	HS3ST3B1	B3GAT2	HS6ST2	GLCE	HS6ST3	B3GAT1	CSGALNACT2	NDST2	B3GALT6	NDST1	EXT1	CHST7	EXT2	CHSY1-1	NDST4	UST	NDST3	B4GALT7	HS3ST3A1	CHST1	CHST3	
16P11 2 PROXIMAL DELETION SYNDROME%WIKIPATHWAYS_20260910%WP4949%HOMO SAPIENS	16p11 2 proximal deletion syndrome	TRAF6	HDAC3	MAPK3	TRAF2	ESR1	MSN	PTEN	PARP4	TP53	DOC2A	CCT6B	PAGR1	SPN	PPP4R1	IGFBP3	PPP4R2	QPRT	PPP4R4	CCT3	CCT2	UNC13A	PPP4R3A	PPP4R3B	KIF22	TLCD3B	ASPHD1	TCP1	KCTD13	TMEM219	ZG16	ALDOA	EZR	KMT2D	INO80E	PAXIP1	KMT2C	MVP	MAZ	CASP8	GDPD3	SEZ6L2	CORO1A	HIRA	PPP4C	CDIPT	HIRIP3	CCT8	CCT7	PPP2R5D	CCT5	CCT4	BPTF	IGBP1	C16orf92	MAP2K6	PRRT2	NR3C1	MAP2K3	TBX6	C16orf54	CCT6A	TAOK2	CCDC6	PPP2CB;PPP2CA	YPEL3	UNC13B	SIAH1	PCNA	REL	PPP2R1A	PPARG	NFKB1	
INTERLEUKIN 1 INDUCED ACTIVATION OF NF KB%WIKIPATHWAYS_20260910%WP3656%HOMO SAPIENS	Interleukin 1 induced activation of NF kB	AJUBA	TRAF6	IRAK1	UBE2N	IL1A	SQSTM1	PRKCZ	NFKB1	TIFA	UBE2V1	
GANGLIO SPHINGOLIPID METABOLISM%WIKIPATHWAYS_20260910%WP1423%HOMO SAPIENS	Ganglio sphingolipid metabolism	ST8SIA1	SLC33A1	ST8SIA3	B3GALT4	ST8SIA5	ST3GAL1	ST3GAL2	ST6GALNAC6	B3GALT1	FUT1	ST3GAL5	B4GALNT1	A3GALT2	
INHIBITION OF EXOSOME BIOGENESIS AND SECRETION BY MANUMYCIN A IN CRPC CELLS%WIKIPATHWAYS_20260910%WP4301%HOMO SAPIENS	Inhibition of exosome biogenesis and secretion by manumycin A in CRPC cells	RAF1	ARAF	MAPK3	NRAS	RAB5B	RAB5C	PDCD6IP	RAB27A	HRAS	RRAS2	MRAS	HGS	RAB5A	RRAS	HNRNPH1	KRAS	BRAF	MAPK1	
OMEGA 3 FATTY ACIDS IN SENESCENCE%WIKIPATHWAYS_20260910%WP5432%HOMO SAPIENS	Omega 3 fatty acids in senescence	HPGD	ALOX15	GSTP1	ALOX12	LTC4S	PTGS1	DPEP1	ALOX5	LTA4H	PTGDS	GSTM4	PTGIS	EPHX2	PLA2G4A	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	ALOX15B	TBXAS1	PTGS2-2	GGT1	FADS2	FADS1	CYP2D6;LOC107987479;LOC107987478-1	FPR2	CYP2C9;CYP2C19	GPR32	ELOVL2	ELOVL5	CYP2E1	PTGES	
CAMKK2 PATHWAY%WIKIPATHWAYS_20260910%WP4874%HOMO SAPIENS	CAMKK2 pathway	PFKFB2	TRPV4	GATM	SPIRE1	MS4A3	HK2	OASL	CCR9	CTSE	ERMAP	GIT1	GALNT9	MAMDC2	HK1	C1QTNF12	ATP10D	TSPAN33	SLC25A21	EP300	AHSP	TMEM176B	IRGC	KLF1	SLCO3A1	RHAG	RELA	ARHGEF7	CCND1	PAK1	VCAM1	SMC1A	FAM20C	KDR	CDC25A	CREB1	ULK1	CAMK1	TNF	CCNE1	IL15	DNM1L	CXCL11	CALM1	PARP1	SREBF1	ACACA	FASN	RAF1	CDH1	NOS1	NLRP1	MAF	CCL5	MTOR	MAP1LC3A	RPS6	ASNS	MAPK1	RAC1	MAPK3	ICAM1	KEAP1	RPS6KB1	AQP1	CAMKK2	ABCA1	HMOX1	HDAC4	NFE2L2	HFE	PFKFB3	MAP1LC3B2;MAP1LC3B-1	CD28	SQSTM1	S100A8	SLC2A1	RASGRP1	TBXT	HIF1A	NFATC2	SIRT1	GCK	SLC2A4	RPTOR	WDR35	CAMK4	EPOR	PCK2	CHRM3	CPOX	TSC1	IFI44L	ATP1B2	MID1	SPINT1	STIM1	HMBS	CRTC2	NEDD4L	CYB5R3	TSPAN8	SLC38A5	FIS1	WFS1	PLAC8	SELL	
AFFECTED PATHWAYS IN DUCHENNE MUSCULAR DYSTROPHY%WIKIPATHWAYS_20260910%WP5356%HOMO SAPIENS	Affected pathways in Duchenne muscular dystrophy	CACNA1F	ITPR2	PRKAA1	SERPINE1	MPO	CACNA1S	PLAU	PRG3	CCN2	FGB	FGA	MCU	FGG	IL6	RYR1	ATP2A1	MCUB	SGCA	MMP2	SCX	GLI1	CASP9	DAG1	PRKAA2	TOMM20	MMP9	TRPC3	TRPC1	SLC25A5	CACNA2D1	TRDN	NFKBIA	IL10	ORAI1	CASQ1	TNNI1	SARAF	CACNB1	DTNA	CACNB2	NOS2	GP2	SSPN	SNTB1	SPP1	IL1A	CACNG1	VDAC1	TNF	HSPA9	NOX4	DMD	IL1B	PLA2G2A-1	CAMK2D	PLA2G4A	SMAD4	ELANE	TGFBR1-1	TRPC6	SMAD2;SMAD3	CAPN3	CYBB	AGTR1	SIGMAR1	PPIF	STIM1	FKBP1A	TGFB1	ITPR1	NFKB1	TGFBR2	ITPR3	
MITOCHONDRIAL CARRIER DEFICIENCY ASSOCIATED WITH SHUTTLE DISTURBANCES%WIKIPATHWAYS_20260910%WP5507%HOMO SAPIENS	Mitochondrial carrier deficiency associated with shuttle disturbances	GLUD1;GLUD2	SLC25A12	GOT2-1	SLC25A22	SLC25A13	
HLA C ALLOTYPES INTERACTIONS WITH KIR ON DNK CELLS%WIKIPATHWAYS_20260910%WP5580%HOMO SAPIENS	HLA C allotypes interactions with KIR on dNK cells	PRKCA	PRKCQ	NLRP7;NLRP2	CSF2	IFNG	ELF3	LCP2	PLCG1	TYROBP	LAT	FYN	TNF	VAV1	PTPN2	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	SYK	ITPR1	PTPN6	RAC1	
NEPHROTIC SYNDROME%WIKIPATHWAYS_20260910%WP4758%HOMO SAPIENS	Nephrotic syndrome	NPHS1	LMNA	ZMPSTE24	NPHS2	WT1	PODXL	ITGA3	CUBN	SCARB2	SMARCAL1	PTPRO	SYNPO	CYP11B1;CYP11B2	TRPC6	ACTN4	CD2AP	INF2	COL4A3	COL4A5	MYH9	LMX1B	CD151	LAMB2	YARS1	PMM2	MYO1E	ARHGDIA	TTC21B	PDSS2	COL4A4	GPC5	EMP2	WDR73	COQ6	ALG1	ARHGAP24	PAX2	ANLN	CTLA4	COQ2	APOL3;APOL4;APOL1;APOL2	PLCE1	E2F3	ITGB4	
KILLER CELL IMMUNOGLOBULIN LIKE RECEPTORS AND HUMAN LEUKOCYTE ANTIGEN C PATHWAY%WIKIPATHWAYS_20260910%WP5576%HOMO SAPIENS	Killer cell immunoglobulin like receptors and human leukocyte antigen C pathway	PRKCA	PRKCQ	CSF2	IFNG	LCP2	PLCG1	TYROBP	LAT	FYN	HRAS	TNF	VAV1	PTPN2	GRB2	CD34	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	SYK	ITPR1	PTPN6	RAC1	
OVARIAN INFERTILITY%WIKIPATHWAYS_20260910%WP34%HOMO SAPIENS	Ovarian infertility	MSH5	DMC1	CYP19A1	INHA	RAD51	ZP2	CDK4	FMR1	ATM	VDR	NR5A1	CDKN1B	CCND2	EGR1	CEBPB	SMAD2;SMAD3	SYNE2	NRIP1	ESR2	PGR	BMPR1B	TSC2	CREB1	AKT1	MTOR	NCOR1	TSC1	PTGER2	ZP3;POMZP3	SMPD1	PRLR	GJA4	LHCGR	TBP	FIGLA	MLH1	DAZL	GDF9	FSHR	
WARBURG EFFECT MODULATED BY DEUBIQUITINATING ENZYMES AND THEIR SUBSTRATES%WIKIPATHWAYS_20260910%WP5216%HOMO SAPIENS	Warburg effect modulated by deubiquitinating enzymes and their substrates	SLC2A1	MYC	HK2	FBP1	OTUB2	LDHA	USP7	USP37	PGAM1	U2AF2	KDR	USP44	PGK1	OTUD7B	HIF1A	USP28	OTUD6B	AKT1	G6PC1	MTOR	FOXO1-1	VEGFA	PIK3CA	VHL	
TRANSCRIPTION ACTIVATION RNA POLYMERASE I AND KAT2A B AND INHIBITION NURD COMPLEX %WIKIPATHWAYS_20260910%WP5565%HOMO SAPIENS	Transcription activation RNA polymerase I and KAT2A B and inhibition NuRD complex	H4C6	POLR1A	ASF1A	POLR1B	ASF1B	MAPK3	POLR1D	MTA1	CREBBP	EP300	TLK2	UBTF	H2BC21	H2AC14	H2AZ2;H2AZ1	H2AJ	HDAC2	H2BC8;H2BC6;H2BC4;H2BC10;H2BC7	H2BC5	H2BC1	H2BC15;H2BC3;H2BC11;H2BC12	PWWP2B	CHD4	H2AC20	CHD3	H2AB2;H2AB3;H2AB1	PWWP2A	KAT2A	POLR1C	RRN3	SRCAP	TAF1D	TAF1B	TAF1C	TAF1A	EP400	MTA2	MBD3	MBD2	GATAD2B	GATAD2A	CDK2AP1	KAT2B	H4-16	HDAC1	TBP	RBBP4	TAF12	HAT1	H4C1	
FOLATE ALCOHOL AND CANCER PATHWAY HYPOTHESES%WIKIPATHWAYS_20260910%WP1589%HOMO SAPIENS	Folate alcohol and cancer pathway hypotheses	ALDH1L1	MTHFR	ALDH1A1	CYP2E1	CREB1	MTR-1	CEBPB	CBS;CBSL	ADH5	
OXIDATIVE DAMAGE RESPONSE%WIKIPATHWAYS_20260910%WP3941%HOMO SAPIENS	Oxidative damage response	TRAF6	C1QC	MAP2K4	BAD	MAPK13	MAPK10	CDKN1A	CDKN1B	C3AR1	MAP3K9	LOC110384692;C4A;C4B_2;C4B	CDKN1C	CR2	TRAF1	CASP9	TRAF2	MAP3K1	TRAF3	C5	CASP3	BCL2	C1QB	CDC42	BAG4	TDP2	C1S	NFKBIE	C1R	APAF1	TNFRSF1B	C5AR1	TNK2	C2	TNF	CYCS-1	PCNA	BAK1	GADD45A	NFKB1	
NANOPARTICLE MEDIATED ACTIVATION OF RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP2643%HOMO SAPIENS	Nanoparticle mediated activation of receptor signaling	MAPK9	NRAS	MAPK8	COL1A1	MAPK14	HRAS	MAPK12	MAPK13	MAPK10	MAPK11	ITGA1	KRAS	GRB2	SOS1	FN1	SRC	AREG	RAF1	PIK3CD	TLN1	AKT3	PXN	EGFR	PTK2	ITGB1	MAP2K2;MAP2K1	MAPK1	
GASTRIC ACID PRODUCTION%WIKIPATHWAYS_20260910%WP2596%HOMO SAPIENS	Gastric acid production	CBLIF	CCK	GRP	PGA4;PGA3;PGA5	SCT	GAST	PGC	VIP	MUC6	
HEMATOPOIETIC STEM CELL GENE REGULATION BY GABP ALPHA BETA COMPLEX%WIKIPATHWAYS_20260910%WP3657%HOMO SAPIENS	Hematopoietic stem cell gene regulation by GABP alpha beta complex	TERF2	DNMT1	CREBBP	DNMT3A	FLT3	GABPB1	ZFX	PTEN	FOXO3	ETV6	SMARCA4	DNMT3B	ATM	EP300	GABPA	SMAD4	GZMH;GZMB-1	MCL1	BCL2L1	BCL2	
OXYSTEROLS DERIVED FROM CHOLESTEROL%WIKIPATHWAYS_20260910%WP4545%HOMO SAPIENS	Oxysterols derived from cholesterol	AKR1D1	CYP7A1	EBP	EPHX2	DHCR7	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	LBP	ACOX2	ACOT2;ACOT1	CYP8B1	NR1I2	NR1H2	RORC	CH25H	IL25	ESR1	SLC27A5	CYP46A1	HSD11B1	ESR2	HSD11B2	INSIG1	SCP2	THEM5	ACOT9	HSD3B7	ACOT8	ACOT7	ACOT11	CYP39A1	ACOT12	SULT2B1	ACOT13	CYP7B1	CYP27A1	DBP	AMACR	BAAT	GPR183	IL17D	SULT2A1-4	ACOT6	IL17C	IL17F	SLC27A2	IL17B	ACOT4	IL17A	
EXERCISE AND HYPERTROPHY IN SKELETAL MUSCLE%WIKIPATHWAYS_20260910%WP516%HOMO SAPIENS	Exercise and hypertrophy in skeletal muscle	IFRD1	IL18	DUSP14	EIF4EBP1	NR4A3	ATF3	ANKRD1	CCN1	IL1A	IL1R1	IFNG	HBEGF	ZEB1	MSTN	EIF4E	VEGFA	JUND	MYOG	WDR1	ADAM10	
GLYCEROL METABOLISM INCLUDING LINKED IMDS%WIKIPATHWAYS_20260910%WP5570%HOMO SAPIENS	Glycerol metabolism including linked IMDs	PC	ALDOA	AQP9	GAPDH-1	SDS	PGAM1	GRHPR	PGK1	GPD2	AGXT	ENO1	HK1	GK	GPD1	PNPLA2	TPI1	GLYCTK	LIPE	PCK1	KHK	PFKL	ALDOB	FBP1	PKLR	G6PC1	AKR1A1	LOC100509620;LOC112267859;AQP7	GPI	MGLL	
MIR TARGETED GENES IN ADIPOCYTES%WIKIPATHWAYS_20260910%WP2001%HOMO SAPIENS	miR targeted genes in adipocytes	TMEM43	FADS1	CAP1	PICALM	PHC2	HIPK3	IGF2R	SRSF10	CSRP1	CYP1B1	ELOVL5	SRSF9	TMED10	CEBPB	LPL	TGFBR2	
NEUROGENESIS REGULATION IN THE OLFACTORY EPITHELIUM%WIKIPATHWAYS_20260910%WP5265%HOMO SAPIENS	Neurogenesis regulation in the olfactory epithelium	DLL1	PSEN1	RTN4	NGFR	MECP2	NTRK1	ERBB4	NTRK3	STAT3	RET	NUMB	FAIM	RTN4R	PLXND1	NUMBL	MRE11	LRP8	SEMA4A	DAB1	NEURL1	APP	NEUROG3	RELN	MYC	ID2-1	MAP2	ASCL1	PAX6	HES1	MEF2C	NRG1	IL17A	TCF4	CDK5	NOTCH1	GHRL	MAPT	NGF	SOX2	ID1	BDNF	CXCL12	JAG1	DISC1	KDM1A	VLDLR	NDEL1	MARK2	NEUROD1	PAFAH1B1	CDK5R1	MAP1B	AGRN	HEY1	GSK3B	NTRK2	
NCRNAS IN WNT SIGNALING IN HEPATOCELLULAR CARCINOMA%WIKIPATHWAYS_20260910%WP4336%HOMO SAPIENS	ncRNAs in Wnt signaling in hepatocellular carcinoma	WNT11	KLF4	DKK1	SOST	WNT7B	PLAU	CTNNB1	TPTEP2-CSNK1E;CSNK1E	FRAT2	SOX7	CSNK2A2	CCND3	SFRP4	CCND2	CSNK2B	TCF7	DVL1	DVL2	FOSL1	CCND1	MYC	DVL3	DKK2	DKK4	FZD10	AXIN1	CSNK2A1;CSNK2A3	SOX17	CER1	LEF1	SERPINF1	CTNNBIP1	SFRP1	SFRP2	SFRP5	CTBP2	CTBP1	TCF7L2	PORCN	TCF7L1	WNT5B	CSNK1A1	RYK-1	APC	KREMEN1	SENP2	ROR1	ROR2	CXXC4	NKD1	NKD2	WIF1	NOTUM	ELAVL1	EZH2	WNT6	WNT1	WNT2	WNT4	WNT10B	WNT10A	FZD2	JUN	FZD5	FZD7	FZD6	FZD9	FZD8	FZD1	FZD3	WNT3A	WNT5A	WNT7A	CHD8	WNT2B	WNT3	LRP6	GSK3B	WNT16	NLK	LRP5	MTDH	
SPINA BIFIDA%WIKIPATHWAYS_20260910%WP5150%HOMO SAPIENS	Spina bifida	MTHFD1	DNMT1	MTHFR	AHCYL2	AHCY	SHMT1	MAT1A	MTRR	DNMT3A	MAT2B	MTR-1	DNMT3B	
UNFOLDED PROTEIN RESPONSE%WIKIPATHWAYS_20260910%WP4925%HOMO SAPIENS	Unfolded protein response	IL1B	EIF2S1	BCL2L11	ATF6	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	ATF4	TP53	NFE2L2	MBTPS1	ERN1	PPP1R15A	XBP1	EIF2AK3	BBC3	PMAIP1	HSPA5	CASP2	BID	RTCB	MBTPS2	TXNIP	DDIT3	BCL2	
MONOAMINE GPCRS%WIKIPATHWAYS_20260910%WP58%HOMO SAPIENS	Monoamine GPCRs	HTR2B	ADRB2	HTR2A	CHRM1	HTR7	ADRA1A	CHRM4	CHRM5	ADRB1	ADRA1D	HTR4	ADRA1B	HRH1	CHRM2	HTR6	HRH2	DRD5	ADRA2C	HTR5A	ADRA2B	DRD1	ADRA2A	DRD2	DRD3	DRD4	HTR1E	HTR1F	HTR1D	HTR1A	HTR1B	CHRM3	ADRB3	
NANOMATERIAL INDUCED APOPTOSIS%WIKIPATHWAYS_20260910%WP2507%HOMO SAPIENS	Nanomaterial induced apoptosis	APAF1	PRF1	ENDOG	DIABLO-1	CASP8	FAS	CFLAR	BAX	HTRA2	FADD	CYCS-1	FASLG	CASP7	CASP9	CASP6	BAK1	BID	AIFM1	CASP3	BCL2	
PCSK9 MEDIATED LDL RECEPTOR DEGRADATION%WIKIPATHWAYS_20260910%WP2846%HOMO SAPIENS	PCSK9 mediated LDL receptor degradation	PCSK9	LDLR	
8Q11 23 RB1CC1 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5412%HOMO SAPIENS	8q11 23 RB1CC1 copy number variation	ATG16L1	ATG13	ATG101	ULK1	WDR45B	TNF	TP53	MAP3K5	RB1	PTK2B	RB1CC1	GABARAPL2	TRAF2	PTK2	GABARAP	
DEREGULATING CELLULAR METABOLISM THROUGH NON GENOTOXIC CARCINOGENS%WIKIPATHWAYS_20260910%WP5571%HOMO SAPIENS	Deregulating cellular metabolism through non genotoxic carcinogens	MYC	LONP1	TSC2	SLC7A7	CLPP	TRAP1	GDF15	MARS1	ATF4	PHB	AKT1	OMA1	MTOR	PHB2	TSC1	HSPD1	LARS1	SESN2	LONP2	IRS1	EIF2A	FOXO1-1	
GPCRS CLASS A RHODOPSIN LIKE%WIKIPATHWAYS_20260910%WP455%HOMO SAPIENS	GPCRs class A rhodopsin like	GPR3	GPR6	MC5R	F2RL1	F2RL3	OR1C1	GPR68	GPR65	GPR63	CCRL2	GHSR	GPER1	OR2D2	NPY1R	OR2T1	APLNR	OR5V1-2	OR2C1	SUCNR1	OR5I1	C3AR1	GPR87	C5AR2	GPR85	MCHR1	OR1Q1	HCAR1	OR2B3	OR2F1-2	OR2J1;OR2J2;OR2J3-2	NMUR2	NMUR1	OR14J1	MLNR	OR7C1;OR7C2-9	PRLHR	NPY5R	OR1F1	OR2H2	AVPR2	OPRM1	SSTR1	SSTR3	SSTR4	SSTR5	OR10A4	HTR1E	OR10A5	HTR1F	OR2A7;LOC107987545;OR2A4	HTR1D	OPN1MW3;OPN1MW2;OPN1MW;OPN1LW	HTR1A	CNR2	HTR1B	OR8B8	OR2W1	OR12D3	OR1D2	OR10J1-2	OPN1SW	CXCR5	ACKR4	OR11A1	ACKR2	GPR37	FPR2	LTB4R	CMKLR1	AGTR1	AGTR2	GPR83	LPAR4	LPAR5	LPAR6	FFAR2	MAS1	CHRM2	F2R	ADRB2	CXCR4	ADRA1B	P2RY6	P2RY4	P2RY2	ADORA3	P2RY1	P2RY12	P2RY13	P2RY10	P2RY11	P2RY14	BDKRB1	GPR32	CHRM3	ADORA2B	PTGFR	PTGDR2	CCR9	TBXA2R	PTGDR	HTR7	PTGIR	RHO	CCR8	CCR6	SSTR2	CX3CR1	MC3R	LHCGR	FSHR	HTR2B	HTR2A	CHRM1	NPY2R	ADORA1	ADRA1A	MTNR1A	MTNR1B	HRH3	GPR75	DRD1	DRD2	DRD3	DRD4	OPN4	OPN3	ADORA2A	OPRL1	CYSLTR2	HCRTR2	HCRTR1	CCR3	NPFFR1	CCR2	FFAR3;GPR42	CHRM4	CHRM5	ADRB1	ADRA1D	HTR4	OPRK1	HRH1	HTR6	HRH2	DRD5	ADRA2C	HTR5A	ADRA2B	ADRA2A	PTGER4	PTGER2	GPR161	NPFFR2	OXTR	RRH	GRPR	GPR174	GPR173	EDNRA	EDNRB	GPR171	GPR37L1	TRHR	PTGER1	OR7A10;OR7A17-11	PTGER3	OR2AG1;OR2AG2	FPR1	OR1I1	MC2R	GALR3	GALR2	GALR1	CYSLTR1	NPBWR1	NPBWR2	OR6B1	CCR10	NTSR1	NTSR2	CCR1	GPR17	XCR1	GPR15	GPR12	NMBR	MC1R	HCAR2;HCAR3	OR6A2	GPR18	ACKR3-2	BDKRB2	GPR19	GPR27	CNR1	GPR25	GPR21	GPR22	GPR20	NPY4R2;NPY4R	OR10H1;OR10H5;OR10H2	BRS3	MC4R	CCKAR	OR2B6;OR2B2-1	CCR7	FFAR1	CCR5	CCR4	GPR39	AVPR1B	GPR34	GPR35	OR2H1-1	OR1A1-1	AVPR1A	OR2S2-1	CCKBR	F2RL2	OR1E1;OR1E2	OR3A2	OR3A1	OPRD1	GPR45	PTAFR	CXCR1	CXCR3	CXCR2	ADRB3	CHML	GPR52	GPR1	OR8D2-1	GPR4	GPR50	
BONE MORPHOGENIC PROTEIN SIGNALING AND REGULATION%WIKIPATHWAYS_20260910%WP1425%HOMO SAPIENS	Bone morphogenic protein signaling and regulation	BMP2	RUNX2	SMURF1	SMAD1	BMPR1B	SMAD6	SMAD4	BMPR1A	TOB2	TOB1	BMPR2	NOG	
NANOPARTICLE TRIGGERED AUTOPHAGIC CELL DEATH%WIKIPATHWAYS_20260910%WP2509%HOMO SAPIENS	Nanoparticle triggered autophagic cell death	UVRAG	AMBRA1	INSR	ATG16L1	ATG14	TSC2	ULK2	ULK1	MAP1LC3A	TSC1	SH3GLB1	ATG3	ATG10	INS;INS-IGF2	ATG12-1	ATG9B	CHAF1A	VMP1	BECN1	BCL2	ATG4A	ATG7	ATG5	
PURINE METABOLISM%WIKIPATHWAYS_20260910%WP4792%HOMO SAPIENS	Purine metabolism	DGUOK	ITPA	ADA	PRPS1	ATIC	ADSL	IMPDH1	HPRT1	ADSS2	XDH	PNP-1	AMPD1	APRT	
GAMMA GLUTAMYL CYCLE FOR THE BIOSYNTHESIS AND DEGRADATION OF GLUTATHIONE%WIKIPATHWAYS_20260910%WP4518%HOMO SAPIENS	Gamma glutamyl cycle for the biosynthesis and degradation of glutathione	GGCT	GGT1	DPEP1	GSS	OPLAH	GCLC	
NPHP1 DELETION SYNDROME%WIKIPATHWAYS_20260910%WP5399%HOMO SAPIENS	NPHP1 deletion syndrome	PTK2B	FLNB	FLNC	MAPK3	NPHP1	FLNA	RPGRIP1L	BCAR1	MAPK1	INVS	
PSORIASIS MECHANISM AND THERAPIES%WIKIPATHWAYS_20260910%WP5537%HOMO SAPIENS	Psoriasis mechanism and therapies	JAK2	IL12RB1	IL1B	CCR6	IL17RC	IL23A	STAT3	TNF	IL12B	CCL20	TYK2	IL22	IL23R	CXCL2;CXCL3;CXCL1-1	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	IL17F	IL17A	CXCL8	
T CELL MODULATION AND DESMOPLASIA IN PANCREATIC CANCER%WIKIPATHWAYS_20260910%WP5078%HOMO SAPIENS	T cell modulation and desmoplasia in pancreatic cancer	PDGFD	PDCD1	PDGFC	IL6	LGALS3	LGALS1	IL13	VEGFB	IL10	VEGFD	PDGFA	IL4	CD40LG	PDGFB	SHH	VEGFA	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	CD28	NT5E	IDO1	PVR	VSIR	B2M	TNFRSF4	HAVCR2	FAS	ENTPD1	PDCD1LG2	CD226	VTCN1	VDR	ICOS	TIGIT	CCL17	CD276	CCL22	TNFRSF9	TNFSF4	FAP	TNFSF9	CXCR4	CXCL12	CD40	LGALS9C;LGALS9;LGALS9B	CD86	CD274	CD80	FASLG	VEGFC	CTLA4	TGFB2	TGFB1	TGFB3	ARG1	PGF	
RETT SYNDROME%WIKIPATHWAYS_20260910%WP4312%HOMO SAPIENS	Rett syndrome	TCF4	STXBP1	GABRA3	NCOR2	MECP2	CHD4	SYNGAP1	TAF1B	KDM5B	TRRAP	FOXG1	SATB2	CRK	GPS2	RHOBTB2	CECR2	HIVEP2	SCN1A	SRRM3	SYNE2	EIF2B2	CDKL5	KCNJ10	SMARCA1	SMC1A	SMARCA2	TBL1XR1	IMPDH2	XAB2	HAP1	SCN2A	SCN8A	SHANK3	SMARCA4	ACTL6B	HDAC5	HTT	HDAC8	GRIN2A	GNAO1	NCOR1	HDAC1	BRAF	GRIN2B	MEF2C	GABRD	GABBR2	
EXRNA MECHANISM OF ACTION AND BIOGENESIS%WIKIPATHWAYS_20260910%WP2805%HOMO SAPIENS	exRNA mechanism of action and biogenesis	DICER1	AGO2	ERI1	XPO5	DROSHA	DGCR8	
INFLUENCE OF LAMINOPATHIES ON WNT SIGNALING%WIKIPATHWAYS_20260910%WP4844%HOMO SAPIENS	Influence of laminopathies on Wnt signaling	TLE1	DICER1	RUNX2	HMGA2	CDK6	TARBP2	AGO2	ICMT	LMNA	ZMPSTE24	CTNNB1	SREBF1	FNTA	WNT10B	CEBPA	ADIPOQ	CEBPB	TCF7	SLC2A4	CCND1	SPP1	EMD	CEBPD	TOR1AIP1	AXIN1	LEF1	GSK3B	HES1	HES5	TCF7L2	PPARG	TCF7L1	CSNK1A1	APC	
SYNAPTIC SIGNALING ASSOCIATED WITH AUTISM SPECTRUM DISORDER%WIKIPATHWAYS_20260910%WP4539%HOMO SAPIENS	Synaptic signaling associated with autism spectrum disorder	CACNA1C	EIF4EBP1	MAPK3	PRKAA1	RHEB	RPS6KB1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	HOMER1	PRKAB2	PRKAB1	PTEN	GRIN2A	GRIN2C	GRIN2B	GRIN2D	CAMK2B	NRAS	PIK3R3	GRM1	HRAS	UBE3A	SYNGAP1	NF1	ARC	KRAS	BDNF	DLG4	GRIN1	RPTOR	TSC2	SHANK3	CAMK4	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	MTOR	GRIN3B	GRIN3A	TSC1	GSK3B	NTRK2	PIK3R2	PIK3CA	PIK3R1	MAPK1	
GENES CONTROLLING NEPHROGENESIS%WIKIPATHWAYS_20260910%WP4823%HOMO SAPIENS	Genes controlling nephrogenesis	EYA1	ILK	NCK2	NOTCH2	NPHS1	GDNF	NPHS2	WT1	LHX1	CD36	FOXC2	FOXC1	RET	ITGA3	CTNNB1	WNT4	ITGA8	CXCR4	CXCL12	NCK1	MAFB	CD2AP	SIX1	TCF21	KDR	LMX1B	FGFR2	PDGFB	LAMB2	PDGFRB	EMX2	FOXD1	SHH	HNF1B	ROBO2	GLI3	HOXD11	HOXA11	PAX2	SLIT2	KIRREL1	FGF8	MAGI2	ETV4	VEGFA	ITGB1	
IL7 SIGNALING%WIKIPATHWAYS_20260910%WP205%HOMO SAPIENS	IL7 signaling	IL7R	MAPK3	JAK1	STAT1	BAD	FYN	STAT3	AKT1	JAK3	IL2RG	IL7	PTK2B	GSK3B	PIK3R2	PIK3R1	STAT5A	STAT5B	MAP2K2;MAP2K1	MAPK1	
MELATONIN METABOLISM AND EFFECTS%WIKIPATHWAYS_20260910%WP3298%HOMO SAPIENS	Melatonin metabolism and effects	PRKCA	TRAF6	PER2	PER1	CAMK2A	CYP1A2	SIRT1	TPTEP2-CSNK1E;CSNK1E	EDN1	CSNK1D	CYP1A1	CLOCK	FOXO1-1	ACHE	MTNR1A	APOE	MTNR1B	ADRB1	AANAT	CYP2D6;LOC107987479;LOC107987478-1	MAP2	CYP2C9;CYP2C19	CYP1B1	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	IRAK1	MAOA	GSK3B	ASMT	ECE1	ARNTL	NFKB1	CRY2	CALM1	CRY1	
MIRNA DEGRADING ENZYMES%WIKIPATHWAYS_20260910%WP4316%HOMO SAPIENS	miRNA degrading enzymes	EXOSC4	PNPT1	XRN1	
HIPPO MERLIN SIGNALING DYSREGULATION%WIKIPATHWAYS_20260910%WP4541%HOMO SAPIENS	Hippo Merlin signaling dysregulation	ITGB3	ITGB2	ITGAE	ITGAL	ITGAX	ITGB8	ITGAV	ITGB7	ITGB6	ITGA4	ITGA3	ITGA2	LATS2	CTNNB1	ITGA1	ITGAD	ITGA8	ITGA7	ITGA6	ITGA5	ITGA9	PRKACB-1	PRKAR2B	CCND1	PRKAR2A	PAK1	MYC	PAK3	PAK2	PRKAR1B	PAK4	KDR	PRKAR1A	PDGFRB	RBX1	KIT	PPP1CA	WWTR1	PLCB4	PPP1CB	PPP1CC	TEAD2	CDH1	CTNNA1	DDB1	FLT3	CDH9	AMOT	EPHA2	CDH7	DCAF1	CXCL10	CDH5	CUL4A	CDH4	CDH3	CDH20	CDH22	CDH24	NGFR	PPP1R12A	CDH10	CDH11	CDH12	NTRK1	CDH13	CDH15	CDH17	CCN2	CDH18	VGLL4	CDH19	PPP1R14A	CDH6	CDH2	IGF1R	CDH16	INSR	PDGFRA	FLT4	CSF1R	EGFR	NRAS	STK3	SAV1	LIN28B	CD44	YAP1-1	HRAS	TEAD1	TEAD3	TEAD4	MST1	LATS1	KRAS	NF2	BUB1B-PAK6;PAK6	AJUBA	MET	ITGA2B	PAK5	FGFR4	PRKACA-1	FGFR3	FGFR2	FGFR1	TEK	NTRK2	CDH8	PTK2	ITGA10	FLT1	ITGA11	FOXM1	ITGB1	ITGAM	ITGB5	ITGB4	
MODULATORS OF TCR SIGNALING AND T CELL ACTIVATION%WIKIPATHWAYS_20260910%WP5072%HOMO SAPIENS	Modulators of TCR signaling and T cell activation	TRAF6	CBLB	CD3G	CD3E	IKBKB	PDPK1	ELOB	IKBKG	CHUK	VAV1	PCBP2	CD247	ITK	CDKN1B	SMARCB1	DGKA	CD3D	TMEM222	GRAP2	RELA	GRB2	ARIH2	UBASH3A	RHOH	RASA2	AGO3;AGO1	NFKBIA	CARD11	BCL10	PTPN6	MALT1	ZFP36L1	RPRD1B	SH2D1A	FIBP	CD5	LCP2	LAT	GNA13	MAP3K8	CD28	MAP3K14	PRKCQ	PLCG1	MAP4K1	CUL5	RNF7	TNFAIP3	LCK	CD8A	MEF2D	DGKZ	NDUFB10	AKT1	SOCS1	REL	PIK3R2	PIK3R1	ZAP70	SH2B3	NFKB1	
RETINOID METABOLISM IN RETINA HEALTHY VS RLBP1 DEFICIENT%WIKIPATHWAYS_20260910%WP5532%HOMO SAPIENS	Retinoid metabolism in retina healthy vs RLBP1 deficient	RLBP1	
TOLL LIKE RECEPTOR SIGNALING RELATED TO MYD88%WIKIPATHWAYS_20260910%WP3858%HOMO SAPIENS	Toll like receptor signaling related to MyD88	MYD88	TRAF6	IRF3	IKBKB	IKBKG	CHUK	TICAM1	RELA	TRAF3	TICAM2	TIRAP	TLR1	TLR9	TLR5	TLR8	TLR6	TLR2	TLR7	TLR4	TLR3	IRAK1	REL	RELB	TBK1	IRF7	TOLLIP	IRAK4	IKBKE	NFKB1	MAPK1	NFKB2	
LIPID METABOLISM IN SENESCENT CELLS%WIKIPATHWAYS_20260910%WP5149%HOMO SAPIENS	Lipid metabolism in senescent cells	PLA2G5	PLA2G6	ALOX5	PLA2G2D	PLA2G1B	PLA2G12A	PLA2G4F	HRAS	PLA2G12B	PLA2G4D	PLA2G4A	PLA2G4E	TP53	PLA2G3	PLA2G7	CDKN1A	SLCO2A1	PLA2G10;LOC100652777	PTGS2-2	
CARDIOMYOCYTE SIGNALING CONVERGING ON TITIN%WIKIPATHWAYS_20260910%WP5344%HOMO SAPIENS	Cardiomyocyte signaling converging on titin	PRKCA	ADRB2	NPR1	ANKRD1	MYPN	CAMK2A	GUCY1B1	ADRB1	PRKACB-1	RAF1	PRKACA-1	PRKAR1A	PRKG2	MDM2-2	TRIM63	FHL1	GUCD1	CSRP3	PLCZ1	ANKRD2	ANKRD23	TTN-1	NBR1	TCAP	FHL2	CRYAB	MAP2K2;MAP2K1	TRIM55	MAPK1	SRF	NUP62	
HUNGER AND SATIETY%WIKIPATHWAYS_20260910%WP5445%HOMO SAPIENS	Hunger and satiety	PYY	GCG	POMC	MC4R	AGRP	NPY	GHRL	LEP	
ALBUTEROL AND BUDESONIDE THERAPY FOR ASTHMA%WIKIPATHWAYS_20260910%WP5503%HOMO SAPIENS	Albuterol and budesonide therapy for asthma	MYL3	ADRB2	ADCY3	ADCY8	PLCB3	PLCB4	GNAS-1	PLCB1	PLCB2	NR3C1	ADCY4	ADCY2	PRKACB-1	ADCY7	ADCY6	PRKAR2A	ADCY5	PRKACA-1	PRKAR1B	PRKAR1A	CREB1	ADCY9	ADCY1	MYL4	MYL2	MYL1	
CATALYTIC CYCLE OF MAMMALIAN FLAVIN CONTAINING MONOOXYGENASES FMOS %WIKIPATHWAYS_20260910%WP688%HOMO SAPIENS	Catalytic cycle of mammalian flavin containing monooxygenases FMOs	FMO3	FMO4	FMO5	FMO1	FMO2	
TRANS SULFURATION ONE CARBON METABOLISM AND RELATED PATHWAYS%WIKIPATHWAYS_20260910%WP2525%HOMO SAPIENS	Trans sulfuration one carbon metabolism and related pathways	MAT2A	SARDH	MTR-1	GPX6	CBS;CBSL	MAT1A	BCAT1	SHMT2	BCAT2	PLD1	MTHFR	SOD3	SOD1	CTH	GPX5	BHMT2	BAAT	ALDH7A1	PCYT1A	DNM1	DMGDH	AHCYL1	CSAD	AHCYL2	SLC25A48	DNMT3L	AHCY	GAD1	PCYT1B	SHMT1	GPX7	PHGDH	DNMT3A	MTHFD2L	MAT2B	GAD2	TYMS	CHKA	AGXT2	GNMT	PSPH	MTHFD1L	ETNK2	DNMT3B	CEPT1	CDO1	AMT	DHFR2;DHFR	CHKB	PCYT2	BHMT	MTHFD1	MTHFD2	CHDH	GPX1	GPX4	PEMT	GSS	PSAT1	CHPT1	GSR	GCLC	GCLM	ETNK1	
MIR TARGETED GENES IN MUSCLE CELL%WIKIPATHWAYS_20260910%WP2005%HOMO SAPIENS	miR targeted genes in muscle cell	NRP1	PKM	GJA1	RHEB	CACNA2D1	ESR1	CCND1	ERBB2	DSG2	FGF2	DHX15	PTBP2	UBE2J1	KIT	SLC38A1	NT5E	PPP3CA	CPNE8	VEZT	ACAA2	SRPRB-1	BACE1	ZEB1	ARF4-1	PWP1	SRSF10	CDIPT	CIAO2A	POGLUT3	RARS1	TPM3	FNDC3B	G6PD	FNDC3A	EIF4E	DHX40	RAB34	RAI14	SRSF9	TMED10	CBFB	MRPL20	BCL2	COMMD9	ANPEP	SLC38A2	ATP6V1C1	SLC4A10	TBCA	MOV10	NCL-1	WNT5A	CHMP2A	ANP32B	PICALM	TRAM1	ADAR	MAGT1	MRC2	SPTLC1	CYP1B1	SH3BGRL3	TMED7	TMED2-1	SEC24A	ATRX	CAPG	PPIF	CSDE1	PXDN	PTMA	MTPN	SEC23A	DNAJB1	POLR2C	PPP1R7	SH3BP4	RTN4	PDLIM7	MPZL1	SLC12A2	COL1A1	GALNT7	COL1A2	TXNRD1	ERBB3	GALNT1	AP3D1	GSTM4	ARCN1	SPCS3	FMNL2	ATP6V0E2;ATP6V0E1	NEDD4	PDCD4	SLC7A11	LAMTOR5	ATP2A2	BET1	AGO3;AGO1	COL3A1	SYNE2	SYNE1	TMEM43	NCOA3	GNA13	EGFR	TPM1	CDKAL1	HES1	E2F3	PRKCI	SLC12A4	NOTCH2	NOTCH1	TYMS	LAMC2	CYP51A1	LAMC1	BACH1	CHORDC1	RAVER2	CDK5RAP1	ANKFY1	SEC62	MTHFD2	VPS39	CDK5RAP3	TMEM41B-1	MBNL1	SCAMP1	CXCL12	CARHSP1	METTL7A-1	PDE3A	WDR82	KCNQ1	FAR1	TMEM87A	HACD3	GRPEL2	PANX1	ATP6V0A1	SNX6	RAB27B	NCEH1	SFXN1	PTPA	GFM1	ASH2L	PTPRJ	PTPRF	COIL	PISD	HYAL3	TMED3	GNL3L-1	GNPNAT1	CTSC	MRPS24	RHOG	AP3B1	CPOX	GAK	SLC7A6	CDCP1	VSNL1	FRG1	BRPF3-1	SSNA1	AMIGO2	FSTL1	NAPG	SLC38A5	PGRMC1	SHOC2	CA12	ITGB4	SPRYD4	TTC9C	WDR11	TPPP3	SNX15	LRRC8A	NUCB1	MAPK7	LAMTOR3	TUSC2	LTN1	ARID4B	SDCBP	LCLAT1	PODXL	ABHD10	MAPK14	KPNA3	MAPK12	TPM4	TPM2	ATG9A	CTNNB1	STX7	ITGA2	RB1	PKN2	UBE4A	CSNK1D	CDKN1A	RAB30	CDKN1B	DMTF1	WDFY1	MATR3	CLOCK	GEMIN7	ERG	SLC1A4	UAP1	CORO1C	SLC9A3R2	CAMTA1	RAB6A	ANAPC1	CD164	CNOT9	SLC25A1	DOCK5	CALCOCO2	SNAP23	DOCK7	TNFAIP2	CHD1	TMEM109	SLC25A13	PLK1	ACP2	SNAP29	SCYL1	HSDL1	ARHGDIA	ARID1A	RCN2	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	RFT1	RBMS1	YWHAQ	LUZP1	NUFIP2	NXN	UHRF1	ACVR1B	CAND1	TP53INP1	E2F1	IGF2BP1	ZNF622	PDLIM5	SLC25A24	MYO10	EHMT2	TM6SF1	SLC4A7	EHMT1	SLC25A32	SRF	NAA15	CDK6	CCNG1	DNMT3A	EZH2	IRS1	MYLIP	ADIPOR2	RAD23B	RDH10	TDG	GFPT1	POLD2	USP1	PPIB	TGFBR2	POLE4	IFRD1	CCN1	ABCG2	MTRR	GPD2	HIPK3	CUL4B	IGF2R	CSRP1	ELMOD2	TXN2	CEBPB	C1QBP	HMOX1	SYPL1	SPARC	HDAC4	POLA2	CSF1	NELFCD	ATAD3A;ATAD3B	MCL1	HSD17B12	GRIA2	PGM1	KRAS	P4HA2	NF2	PSAT1	CLDN1	GPAM	AXL	MET	PAFAH1B2	STRN	FADS2	MYO1E	PHLDB2	THBS1	NFIA	IPO4	LRP1	LMNB2	LPL	
NEUROINFLAMMATION AND GLUTAMATERGIC SIGNALING%WIKIPATHWAYS_20260910%WP5083%HOMO SAPIENS	Neuroinflammation and glutamatergic signaling	LRRC8A	ADCY8	FOS	SLC1A4	DLD	PDHA1	CNTF	CREB1	FGF2	TNF	IL10RB	GRIN2A	ADCY1	SLC38A1	GRIN2C	LIF	GRIN2B	GRIN2D	IGF1	CALM1	GOT1-1	GLUL	NSMF	SLC1A6	IL1B	SLC38A3	GLS2	GRIA3	PPP1CA	GRIA4	SLC1A3	TRPM4	DAO	SLC6A9	GRM5	GRIK5	GRIK3	GRIK4	GRIK1	PLCB3	GRIK2	SLC7A10	PLCB4	PPP1CB	GRM2	SLC17A6	PPP1CC	GRM4	SLC17A7	GRM7	TNFRSF1A	GRM8	PLCB1	DLAT	PLCB2	IRS1	TRAF5	LTA	BDNF	SRR	LRRC8C	LRRC8D	LRRC8B	LRRC8E	TGFBR1-1	BCL2	DISC1	CAMKK1	SLC38A2	IL13RA1	GRIN1	NOS1	TNFRSF1B	IL1R1	IFNGR2	AKT1	GRIN3B	GRIN3A	STAT6	TGFB2	IL4R	TGFB1	TGFB3	SOCS3	NFKB1	IL10RA	NFKB2	MAPK1	TGFBR2	IL6R	MAPK3	JAK1	STAT1	STAT3	IL12B	IL6	IL13	SLC1A2	IL6ST	SHMT2	CAMKK2	IL10	INSR	GFAP	CFL1	IL4	IL1A	IFNG	IL12A	SMAD7	SLC1A1	IL1R2	PRKCG	PRKCB	PRKCA	SLC2A1	ADCY3	CAMK2B	GRIA1	GLS	SHMT1	CAMK2D	PHGDH	CAMK2A	GRIA2	PSPH	GRM1	CAMK2G	NGF	ARC	SMAD4	PSAT1	SMAD2;SMAD3	IFNGR1	PRKACA-1	CAMK4	TGFBR3	SLC38A5	
ACUTE VIRAL MYOCARDITIS%WIKIPATHWAYS_20260910%WP4298%HOMO SAPIENS	Acute viral myocarditis	ITGB2	ILK	ITGAL	MAPK3	JAK1	RAC3	STAT1	ABL2	STAT3	IL12B	CCR3	EDN1	IL6	SGCD	SGCA	SGCB	CASP9	DAG1	SGCG	MMP9	SOS1	BCL2L1	CASP3	IL10	SRC	CCND1	IL2	IFNG	CD40LG	ENDOG	CREB1	IL12A	AIF1	TLR4	TNF	TLR3	CD55	ACTB-1	CYCS-1	CD4	PYCARD	ABL1	CASP7	CASP1	CASP6	CASP2	BID	RASA1	MYH6	DMD	CASP8	BAX	PARP1	EIF4G1	TICAM1	CXCR4	LAMA2	NOD2	CAAP1	HLA-DMA	PTCRA	BCL2	DFFB	DFFA	CXADR	KRT8	CHRAC1	BNIP2	PABPC1;PABPC3	EIF4G2	NOS1	CCR5	TLR5	FYN	AKT1	CD80	SOCS1	GSK3B	CAV1	PIK3R1	TGFB1	MAPK1	NFKB2	
LIPID PARTICLES COMPOSITION%WIKIPATHWAYS_20260910%WP3601%HOMO SAPIENS	Lipid particles composition	APOC3	APOC2	APOA1	CETP	APOA2	APOE	APOB	LPL	LDLR	LCAT	
ULTRACONSERVED REGION 339 MODULATION OF TUMOR SUPPRESSOR MICRORNAS IN CANCER%WIKIPATHWAYS_20260910%WP4284%HOMO SAPIENS	Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer	CCNE2	TP53	
METABOLISM OF TETRAHYDROCANNABINOL THC %WIKIPATHWAYS_20260910%WP4174%HOMO SAPIENS	Metabolism of tetrahydrocannabinol THC	CYP2C9;CYP2C19	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
MESODERMAL COMMITMENT PATHWAY%WIKIPATHWAYS_20260910%WP2857%HOMO SAPIENS	Mesodermal commitment pathway	DLL1	GATA6	FOXC2	VAV3	FOXC1	PITX2	HPRT1	ZFHX4	SESN1	CCND1	HNF4A	PRKAR1A	AXIN2	SOX17	PAX6	TOX3	CTBP2	SRF	BMP4	TCF4	IQCJ-SCHIP1;SCHIP1	ELK4	PBX1	CRTC1	FOXA1	SOX2	TEAD2	ACACA	PPP2CB;PPP2CA	FOXA2	SOX21	TRIM28	WNT3A	CEP250	RARG	DIP2A	RPL38	HES7	ACVR1	WNT3	EOMES	WDHD1	ZNF281	PIAS1	EMSY	ADAM19	TOX	TWSG1	WDFY2	BCORL1	BHLHE40	MACF1	MBTD1	ACVR2A	EPB41L5	RARB	UBR5	ATP8B2	PBX3	GDF3	TRERF1	NLK	CCDC88A	NABP2	TRIM71	SETD2	NCAPG2	PHF6	JAK2	CSRP2	ZIC2	ZIC3	TRIM5	KLF4	DKK1	JARID2	KDM6A	SLC2A12	MSGN1	TET1	PARP8	ARL4A	DDAH1	CUL4B	PLCH1	AEBP2	MTF2	HAND1	AHDC1	C9orf72	WDCP	AMH	ASCC3	SNAI1	ZNF462	ELP4	GRHL2	ACVR2B	TBX3	MEIS1	RGS10	C1QBP	TBX1	ARID5B	BMP7	EXT1	EXT2	GATA3	NFE2L2	HTT	AXIN1	KLF5	LEF1	FGF8	TCF7L1	POU5F1;POU5F1B	HMGA2	CHRD	NANOG;NANOGP8	YAP1-1	TEAD1	DNMT3B	MIXL1	NODAL	LATS1	SMAD1	SMAD4	TBX6	FZD5	FZD4	CCDC6	SMAD2;SMAD3	FZD8	PRKACA-1	BMPR1A	FGFR1	LEFTY2;LEFTY1	BMPR2	NOG	FOXH1	INHBA	SMAD6	
KIT RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP304%HOMO SAPIENS	Kit receptor signaling	JAK2	TEC	MAPK3	STAT1	BAD	MAPK14	STAT3	PTPN11	EP300	VAV1	GAB2	RPS6KB1	CBL	GRB2	INPP5D	SOS1	CRK	LYN	GRB10	STAT5A	STAT5B	MATK	BTK	SHC1-1	MITF	DOK1	PTPN6	SRC	SOCS6	SH2B2	KITLG	KIT	PRKCB	PRKCA	GRB7	MAPK8	PLCG1	HRAS	RPS6KA3	RPS6KA1	MAPT	CRKL	RAF1	FYN	FOXO3	AKT1	SOCS1	RPS6	PIK3R2	PIK3R1	MAP2K2;MAP2K1	MAPK1	
CAFFEINE IN BLOOD VESSELS%WIKIPATHWAYS_20260910%WP5601%HOMO SAPIENS	Caffeine in blood vessels	ADCY3	RYR3	RYR2	ADCY8	PPP1R12A	PPP1CB	GUCY1A2	ADRA1A	GUCY1A1	PDE3A	ADCY4	ADCY2	ADRA1D	ADCY7	ADCY6	PDE3B	ADRA1B	CALM3;CALM1	MYLK	ADCY5	PDE4B	PDE4A	PDE4D-1	PPP1R12C	ADORA3	NOS3	ADCY9	ADORA2A	ADORA2B	ADCY1	CALM1	CALM2	
HOST PATHOGEN INTERACTION OF HUMAN CORONAVIRUSES INTERFERON INDUCTION%WIKIPATHWAYS_20260910%WP4880%HOMO SAPIENS	Host pathogen interaction of human coronaviruses interferon induction	MYD88	TRAF6	MAP3K7	IRF3	JAK1	MAPK8	STAT1	MAVS	MAPK14	IKBKB	RIPK1	TYK2	IKBKG	CHUK	TICAM1	FOS	JUN	TRAF3	NFKBIA	IFNAR2	STAT2	OAS3	TLR7	OAS1	IRF9	IFNAR1	IFIH1	EIF2AK2	TBK1	IKBKE	NFKB1	DDX58	
CARNOSINE METABOLISM OF GLIAL CELLS%WIKIPATHWAYS_20260910%WP5313%HOMO SAPIENS	Carnosine metabolism of glial cells	SLC6A6	SLC15A2	CARNS1	SLC15A4	
MIR 124 PREDICTED INTERACTIONS WITH CELL CYCLE AND DIFFERENTIATION %WIKIPATHWAYS_20260910%WP3595%HOMO SAPIENS	mir 124 predicted interactions with cell cycle and differentiation	STK11	PRKAA1	CTDSP1	STRADB	PTBP1	SIX4	
MITOCHONDRIAL COMPLEX I ASSEMBLY MODEL OXPHOS SYSTEM%WIKIPATHWAYS_20260910%WP4324%HOMO SAPIENS	Mitochondrial complex I assembly model OXPHOS system	NDUFA8	NDUFA7	NDUFA6	NDUFA5	NDUFA3	NDUFAB1	NDUFS5-1	NDUFA12	NDUFB11	NDUFA10	NDUFA13	NDUFC1	NDUFS6	NDUFS4	NDUFB3	NDUFS3	NDUFS2	NDUFS1	NDUFB9	ECSIT	NDUFB8	NDUFB7	DMAC2	NDUFB10	FOXRED1	NDUFB6	TMEM186	NDUFB5	TMEM70	NDUFB4	NUBPL	ACAD9	NDUFB2	NDUFAF6	NDUFAF7	NDUFB1	NDUFAF4	NDUFAF2	NDUFAF3	TMEM126B	NDUFAF1	NDUFC2;NDUFC2-KCTD14	NDUFV3	NDUFV2	NDUFV1	TIMMDC1	
SPLICING FACTOR NOVA REGULATED SYNAPTIC PROTEINS%WIKIPATHWAYS_20260910%WP4148%HOMO SAPIENS	Splicing factor NOVA regulated synaptic proteins	EPB41L2	NCDN	EFNA5	NEO1	MAPK9	NTNG1	CADM3	APLP2	CADM1	CASK	ANK3	TERF2IP	MAPK4	SNW1	ATP2B1	PRKCZ	RAP1GAP	GRIK2	PLCB4	KCNQ2	CAMK2G	KCNJ6	CDH2	STX2	DAB1	GRIN1	CLASP1	AGRN	KCNMA1	CAV2	GPHN	GRIN2B	EPB41	GABRG3;GABRG2	CLSTN1	STXBP2	CSN3	EPB41L1	CHL1	GABBR2	
GPCRS OTHER%WIKIPATHWAYS_20260910%WP117%HOMO SAPIENS	GPCRs other	PTGFR	HTR7	UTS2R	CCR2	C5AR2	OR2F1-2	ADRA1D	CHRM2	OR1F1	SSTR2	F2R	OR10A5	OR2A7;LOC107987545;OR2A4	HTR1F	GRPR	EDNRA	PROKR2	FSHR	ADRB2	HTR2A	SMO	OR2M4	GPR61	GPR62	CELSR1	GRM1	NTSR1	RXFP1	OR7E24-1	CELSR3	GPR17	RXFP3	GPR176	GPR132	ADGRE3	S1PR1	GNRHR	GPR135	ADGRV1	OR8G1;OR8G5	GPR18	TAAR5	OR1J2	TAAR2	CNR1	OR1N1	GPR162	LTB4R2	ADGRF5	VN1R1	OR6C3	GPR88	GPR84	OR2B6;OR2B2-1	MCHR2	GHRHR	ADGRG1	CCR5	HRH4	ADORA3	OR6C2;OR6C68	ALG6	OR5AC2-2	GPR55	DRD3	ADGRD1	DRD4	P2RY13	GPR143	OR2H1-1	ACKR1	P2RY11	OR2A5	ADORA2A	LGR6	ADGRL2	CCKBR	ADGRL3	CHRM3	OR1E1;OR1E2	OR3A1	CELSR2	CXCR1	GPR183	CXCR3	CXCR2	GPR83	
FOXP3 IN COVID 19%WIKIPATHWAYS_20260910%WP5063%HOMO SAPIENS	FOXP3 in COVID 19	IL6R	IL2RA	IL2	IL2RB	IL7R	FOXP3	STAT3	CD86	CD80	IL2RG	IL6	IL6ST	CD28	STAT5A	STAT5B	
SARS COV 2 REPLICATION ORGANELLE FORMATION%WIKIPATHWAYS_20260910%WP5156%HOMO SAPIENS	SARS CoV 2 replication organelle formation	PIK3R4	
PHYSIOLOGICAL AND PATHOLOGICAL HYPERTROPHY OF THE HEART%WIKIPATHWAYS_20260910%WP1528%HOMO SAPIENS	Physiological and pathological hypertrophy of the heart	PPP3CA	PPP3CB	CAMK2D	CTF1	MAPK8	MAPK14	STAT3	GATA4	MAPK11	AGT	MYEF2	RHOA	EDN1	LIFR	FOS	MAP2K3	JUN	IL6ST	NFATC4	CALM1	PRKCB	MAPK1	PRKCE	RAC1	
NRF2 PATHWAY%WIKIPATHWAYS_20260910%WP2884%HOMO SAPIENS	NRF2 pathway	SLC5A6	ALDH3A1	SLC5A9	CES3	CES2	EPHA3	SLC5A3	SLC5A5	CES5A	PTGR1-1	SLC5A4	RXRA	PRDX6	SLC6A5	SLC2A9	SLC6A7	SLC6A19	SLC6A8	MAFF	SLC2A5	PPARD	SLC2A6	SLC2A7	SLC2A8	SLC2A11	SLC2A10	ABCC5	SLC2A13	SLC39A11	SLC39A10	SLC39A13	SLC39A12	EGR1	SLC39A14	SLC5A11	SLC5A12	SLC5A10	CBR3	TXNRD3	PDGFB	FTL-1	SLC6A9	ABCC3	ABCC4	G6PD	ABCC2	BLVRB	GSR	GSTT2B;GSTT2	GSTM1;GSTM2-1	GSTA3;GSTA1	GCLC	ME1	GSTA3;GSTA5;GSTA1;GSTA2	SLC6A1	GCLM	SLC6A2	GGT1	SLC6A3	SLC6A4	SLC5A7	TGFB2	TGFB1	MGST3	EPHA2	MGST2	TGFBR2	DNAJB1	AGER	SRXN1	CES1	SERPINA1	SLC2A12	HBEGF	TXNRD1	GSTM4	GSTM3	PRDX1	KEAP1	HGF	MAFG	SLC7A11	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	TGFA	SLC6A18	SOD3	SLC5A8	HMOX1	SLC6A6	NFE2L2	UGT1A1;UGT1A6	SLC39A2	SLC39A1	SLC39A4	SLC39A3	SLC5A2	SLC6A20	NRG1	SQSTM1	SLC2A1	GSTP1	FGF13	SLC6A11	HSP90AB1	CYP2A13;CYP2A6;CYP2A7-1	SLC2A2	CBR1-1	HSP90AA1	GSTA4	SLC5A1-1	SLC2A4	NQO1	HSPA1A;HSPA1B	SLC39A9	FTH1	SLC39A6	SLC39A5	SLC39A8	SLC39A7	SLC6A17	SLC6A16	SLC6A15	SLC6A14	SLC6A13	TXN	PGD	
SUPPRESSION OF HMGB1 MEDIATED INFLAMMATION BY THBD%WIKIPATHWAYS_20260910%WP4479%HOMO SAPIENS	Suppression of HMGB1 mediated inflammation by THBD	CHUK	IKBKG	THBD	AGER	RELA	HMGB1-1	NFKBIA	NFKB1	IKBKB	
CCL18 SIGNALING%WIKIPATHWAYS_20260910%WP5097%HOMO SAPIENS	CCL18 signaling	ZEB2	AK4-1	CDH2	PTK2B	CCR8	MMP2	
DUAL HIJACK MODEL OF VIF IN HIV INFECTION%WIKIPATHWAYS_20260910%WP3300%HOMO SAPIENS	Dual hijack model of Vif in HIV infection	ELOB	UBB;UBC	RUNX1	RBX1	CUL5	CBFB	ELOC-1	
NEOLACTO SERIES SPHINGOLIPID METABOLISM%WIKIPATHWAYS_20260910%WP5302%HOMO SAPIENS	Neolacto series sphingolipid metabolism	NEU2	FUCA1	ST3GAL4	NAGA	B4GALT1	B3GNT5	FUT2	FUT1	FUT6;FUT5;FUT3	B4GALT4	B4GALT3	
ALA OXYLIPIN METABOLISM%WIKIPATHWAYS_20260910%WP5136%HOMO SAPIENS	ALA oxylipin metabolism	ALOX15	ALOX5	EPHX2	
HEDGEHOG SIGNALING%WIKIPATHWAYS_20260910%WP4249%HOMO SAPIENS	Hedgehog signaling	SMO	CSNK1G1	SPOP	DHH	TPTEP2-CSNK1E;CSNK1E	CUL3	ARRB1	CSNK1D	ARRB2	SMURF1	GLI1	LRP2	CCND2	PTCH1	BCL2	PRKACB-1	CCND1	PRKACA-1	HHIP	GRK3	GRK2	KIF3A	BOC	EVC2	CSNK1G3	PTCH2	IHH	GLI2	FBXL17	SHH	KIF7	EVC	SPOPL	GLI3	GAS1	SMURF2	CSNK1G2	GPR161	CDON	CSNK1A1	
AMINO ACID METABOLISM IN TRIPLE NEGATIVE BREAST CANCER CELLS%WIKIPATHWAYS_20260910%WP5213%HOMO SAPIENS	Amino acid metabolism in triple negative breast cancer cells	SLC2A1	SLC7A11	SLC1A5	GLS	PSAT1	PHGDH	PSPH	
DNA REPLICATION%WIKIPATHWAYS_20260910%WP466%HOMO SAPIENS	DNA replication	UBB;UBC	MCM2	POLE2	RPA3	CDK2	POLA1	UBA52	MCM7	POLE	RFC5	RFC3	RFC4	MCM3	RFC2	MCM4	MCM5	MCM6	PRIM2	PRIM1	ORC5	RFC1	ORC4	CDC45	ORC6	ORC1	ORC3	CDC7	ORC2	CDC6	POLD3	POLD4	POLA2	POLD1	POLD2	PCNA	GMNN	MCM10	CDT1	DBF4	RPA1	RPA2	
MFAP5 MEDIATED OVARIAN CANCER CELL MOTILITY AND INVASIVENESS%WIKIPATHWAYS_20260910%WP3301%HOMO SAPIENS	MFAP5 mediated ovarian cancer cell motility and invasiveness	ITGB3	RYR3	PRKCQ	MAPK3	CREB1	ITGAV	PLCG1	TNNC1	MFAP5	JUN	PTK2	MAPK1	ITPR3	
ESTROGEN METABOLISM%WIKIPATHWAYS_20260910%WP697%HOMO SAPIENS	Estrogen metabolism	COMT	NQO1	STS	CYP1A2	UGT1A1;UGT1A6	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	CYP1B1	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	CYP1A1	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	ARSD-1	ARSL	GSTM1;GSTM2-1	GSTA3;GSTA1	
GALANIN RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP4970%HOMO SAPIENS	Galanin receptor pathway	SLC2A4	VAMP2	CREB1	YAP1-1	BCL2L11	CDKN1A	POMC	CDKN1B	FOS	IL6	CDKN1C	CRP	ADIPOQ	VEGFA	INS;INS-IGF2	PPARG	
ZINC HOMEOSTASIS%WIKIPATHWAYS_20260910%WP3529%HOMO SAPIENS	Zinc homeostasis	SLC30A2	SLC30A5	SLC30A4	SLC30A1	MT3	MTF1	SLC30A9-1	MT2A	SLC39A11	SLC39A10	SLC39A13	SLC39A12	SLC39A14	SLC39A2	SLC39A1	SLC39A4	SLC39A9	SLC39A3	SLC39A6	SLC39A5	SLC39A8	SLC39A7	SLC30A10	SLC30A7	SLC30A6	SLC30A8	SLC30A3	
RNA POLYMERASE II TRANSCRIPTION THE PREINITIATION COMPLEX%WIKIPATHWAYS_20260910%WP5563%HOMO SAPIENS	RNA polymerase II transcription the preinitiation complex	POLR2C	ERCC3	TAF7	TAF6	TAF5	ELK1	NELFB	NELFA	NELFCD	MED9	NELFE	CCNC-1	POLR2A	MED19	MED16	MED18	MED17	MED12	MED11	MED14	MED13	MED10	MED1	MED8	MED4	GTF2F1	MED27	MED26	MED6	MED29	MED7	MED23	MED22	MED25	MED24	THRA	MED21	MED20	GTF2A1	MED28-1	CTDP1	MED15	MED30	POLR2D	POLR2L	POLR2M	TAF10	TAF11	TAF8	MED31-1	TAF4	TAF3	TAF2	TAF1	GTF2B	TAF9	GTF2E2	POLR2B	POLR2E	POLR2F	CDK8	POLR2G	POLR2H	POLR2I	TBP	TAF12	TAF13	POLR2J;POLR2J2;POLR2J3	
DDX1 AS A REGULATORY COMPONENT OF THE DROSHA MICROPROCESSOR%WIKIPATHWAYS_20260910%WP2942%HOMO SAPIENS	DDX1 as a regulatory component of the Drosha microprocessor	RAD50	NBN	MRE11	DDX1	DROSHA	ATM	DGCR8	
TRYPTOPHAN CATABOLISM LEADING TO NAD PRODUCTION%WIKIPATHWAYS_20260910%WP4210%HOMO SAPIENS	Tryptophan catabolism leading to NAD production	IDO1	NMRK1	NMNAT3	NADSYN1	NMNAT2	NMRK2	NAPRT	NMNAT1	NAMPT	QPRT	AADAT	HAAO	KMO	TDO2	KYNU	AFMID	
INSULIN SIGNALING%WIKIPATHWAYS_20260910%WP481%HOMO SAPIENS	Insulin signaling	MAPK9	MAPK7	PRKAA1	MAPK6	MAPK4	MAP4K5	MAPK14	MAPK12	ELK1	MAPK13	IKBKB	PDPK1	MAPK10	MAPK11	FOS	RHEB	RAPGEF1	CBL	PRKAA2	CRK	EGR1	LIPE	SNAP23	SORBS1	SNAP25	KIF3A	RPS6KA5	XBP1	MAP3K8	MAP3K3	GSK3A	MAP3K14	SRF	GRB14-1	VAMP2	STXBP1	MAPK8	RPS6KA3	RPS6KA2	RPS6KA1	MAP3K9	MAP2K7	IRS1	EIF4E	MAP3K4	IRS2	MAP2K6	MAP2K3	FOXO1-1	JUN	MAP3K1	MAP3K10	RAF1	MAP3K11	TSC2	IRS4	KIF5B	AKT2	INPPL1	AKT1	CBLC	MAP3K5	MTOR	RPS6KA4	ENPP1	MAP3K6	GYG1	SOCS1	INPP4A	STXBP3	GSK3B	STXBP4	RRAD	PIK3R2	PPP1R3A	PIK3R1	EHD1	ARHGAP33	SOCS3	EHD2	MAP3K13	MAP2K2;MAP2K1	ARF1	MAPK1	FLOT1	RAC1	TRIB3	FLOT2	EIF4EBP1	MINK1	CBLB	MAP3K7	RHOJ	PTPN1	RHOQ	ARF6	MAPK3	CYTH3	STX4	MAP2K4	SGK3;C8orf44-SGK3	MAP3K2	REG1B;REG1A	CAP1	MYO1C	PRKCD	PFKM	GAB1	GYS2	PTPN11	MAP3K12	GYS1	SGK1-1	IGF1R	RPS6KB1	GRB2	SOS1	GRB10	SHC1-1	SHC2	SH2B2	INSR	PTEN	SOS2	PRKCI	PRKCH	STXBP2	PRKCB	PRKCA	SLC2A1	RPS6KB2	PRKCQ	PIK3R4	PIK3R3	PRKCZ	HRAS	MAP4K3	MAP4K4	MAP4K1	MAP4K2	SLC2A4	PFKL	RPS6KA6	PTPRF	FOXO3	PIK3CD	PIK3C2G	SHC3	PIK3CB	PIK3C2A	PIK3CG	TSC1	MAP2K5	TBC1D4	PIK3CA	RAB4A	PIK3C3	
LINOLEIC ACID METABOLISM AFFECTED BY SARS COV 2%WIKIPATHWAYS_20260910%WP4853%HOMO SAPIENS	Linoleic acid metabolism affected by SARS CoV 2	ACE2	ELOVL2	ELOVL5	ACOT2;ACOT1	FADS2	FADS1	
ACUTE MYELOID LEUKEMIA%WIKIPATHWAYS_20260910%WP5293%HOMO SAPIENS	Acute myeloid leukemia	EIF4EBP1	MAPK3	CSF2	BAD	MPO	SPI1	STAT3	DUSP6	IKBKB	BCL2A1	PPARD	CEBPE	FCGR1A	IKBKG	CHUK	RUNX1T1	JUP	ZBTB16	CEBPA	RPS6KB1	RELA	GRB2	GLI1	CCNA1	SOS1	STAT5A	STAT5B	TCF7	CCND1	MYC	RUNX1	CSF1R	IL3	CCNA2-1	SOS2	LEF1	PIM2	KIT	TCF7L2	TCF7L1	PML	RPS6KB2	PER2	NRAS	PIK3R3	CD14	HRAS	KRAS	RAF1	ARAF	FLT3	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	MTOR	RARA	PIK3R2	BRAF	PIK3CA	PIK3R1	PIM1	ITGAM	MAP2K2;MAP2K1	NFKB1	MAPK1	
ARACHIDONATE EPOXYGENASE EPOXIDE HYDROLASE%WIKIPATHWAYS_20260910%WP678%HOMO SAPIENS	Arachidonate epoxygenase epoxide hydrolase	CYP2J2-1	GSTP1	COX8A	COX5A	CYP2C9;CYP2C19	EPHX2	
INFLUENZA A VIRUS INFECTION%WIKIPATHWAYS_20260910%WP1438%HOMO SAPIENS	Influenza A virus infection	BCL2	
GIP AND GLP 1 FUNCTION BY TISSUE%WIKIPATHWAYS_20260910%WP5509%HOMO SAPIENS	GIP and GLP 1 function by tissue	GCG	GIP	
LUNG PATHOLOGY OF COVID 19%WIKIPATHWAYS_20260910%WP5146%HOMO SAPIENS	Lung pathology of COVID 19	IL18	CXCL10	IRF3	IL1B	CSF2	MAVS	TLR8	STING1	TLR7	TNF	TLR3	CCL13;CCL2	CXCL9	CGAS	IL6	IFIH1	TBK1	NFKB1	CXCL11	DDX58	
ANGIOGENESIS%WIKIPATHWAYS_20260910%WP1539%HOMO SAPIENS	Angiogenesis	KDR	FGFR2	CREBBP	PDGFRA	NOS3	HIF1A	PLCG1	PDGFB	MAPK14	TIMP2	FGF2	TIMP3	AKT1	ANGPT1	TEK	SMAD1	VEGFA	MMP9	PTK2	PIK3CA	FLT1	ARNT	MAPK1	SRC	
SARS COV 2 ALTERING ANGIOGENESIS VIA NRP1%WIKIPATHWAYS_20260910%WP5065%HOMO SAPIENS	SARS CoV 2 altering angiogenesis via NRP1	NRP1	ACE2	FURIN	KDR	VEGFA	
MRNA PROTEIN AND METABOLITE INDUCED STRESS PATHWAY BY CYCLOSPORIN A%WIKIPATHWAYS_20260910%WP3953%HOMO SAPIENS	mRNA protein and metabolite induced stress pathway by cyclosporin A	KEAP1	SLC3A2	SLC7A11	SLC1A5	SLC7A5	ATF4	NFE2L2	
BASE EXCISION REPAIR%WIKIPATHWAYS_20260910%WP4752%HOMO SAPIENS	Base excision repair	SMUG1	NTHL1	POLE2	APEX1	XRCC1	POLE3	PARP1	FEN1	OGG1	POLB	PARP3	APTX	POLG	POLG2	POLL	TDP1	POLE	ADPRS	NEIL1	RFC5	RFC3	RFC4	RFC2	PARP2	RFC1	PNKP	HMGB1-1	UNG	POLD3	POLD4	TDG	PARP4	POLD1	MPG	POLD2	LIG1	PCNA	MUTYH	MBD4	LIG3	NEIL3	NEIL2	POLE4	
MALE INFERTILITY%WIKIPATHWAYS_20260910%WP4673%HOMO SAPIENS	Male infertility	SLC46A1	EP300	CLU	CLOCK	POLG	ESR1	RFC1	TNF	MDM2-2	GNAO1	SOX5	HLA-DRA	LIG4	ARNTL	DAZL	XPC	MSH5	DDX20	XRCC4	KDM3A	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	FAS	PARP1	ATM	POLB	GPX1	PEMT	APOB	BCL2	NOS1	PMS2	MLH1	SIRPA;SIRPB1;SIRPG	ETV5	MTRR	ERCC1	CREBBP	AR	ERCC2	MTR-1	CYP1A1	MMP2	MMP9	CCNA1	CCNK	IHO1	UBR2-2	SLC16A7	CYP26B1	RGS9	RAG1	NANOS1	USP8	INSR	NOS2	PRDM7;PRDM9	MTHFR	PRM3	SPATA17	ESR2	SOD3	MSH4	TSSK6	TSSK4	TCN2	DDX4	STRA8	UBD	MOV10L1	TMEM132E	BRCA2	UBE2B	XRCC2	NFE2L2	CCNT1	XRCC3	PUM2	CCNT2-1	PIWIL2	AHR	CRISP2	EPPIN;EPPIN-WFDC6	PIWIL1	PIWIL4	PIWIL3	SPO11	CAT	SEPTIN12	YBX2	CHD2	CDK9	KLK3;KLK2	ABCB1	HORMAD2	HORMAD1	MSMB	PRMT6	PACRG	TEX15	AGO2	AHRR	USP26;USP29	SHMT1	LTF	CYP17A1	PON2	PON1	DND1	CXXC1	ABLIM1	OR2W3	PEX10	LRWD1	CDC42BPA	MLH3	BHMT	REC8	FOLH1B;FOLH1	CTCFL	MTHFD1	TRIP13	BRDT	PSAT1	SRD5A2	NQO1	NOS3	FASLG	THBS1	XRCC5	H4C1	
HISTONE MODIFICATIONS%WIKIPATHWAYS_20260910%WP2369%HOMO SAPIENS	Histone modifications	H4C6	H3-3A	KMT2D	KMT2C	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	EZH2	AEBP2	KMT2E	SETD4	SETD5	SMYD2-1	SETD3	SMYD5	SETD9	SETD6	KMT2B	DOT1L	SETD7	PRDM2	NSD1	SMYD1	KMT2A	KMT5B	SMYD4	KMT5A	SMYD3	SETDB1	SUV39H1	KMT5C	EED	SETD1B	SUV39H2	SETD1A	SETMAR	ASH1L	SETBP1	EZH1	H4-16	SET-1	EHMT2	SETD2	EHMT1	H4C1	
COVID 19 AND ENDOTHELIAL CELL SENESCENCE%WIKIPATHWAYS_20260910%WP5256%HOMO SAPIENS	COVID 19 and endothelial cell senescence	IL17RA	IL17RC	TLR4	IL17A	ANO6	
SPHINGOLIPID METABOLISM IN SENESCENCE%WIKIPATHWAYS_20260910%WP5121%HOMO SAPIENS	Sphingolipid metabolism in senescence	PRKCA	CDK4	CDK2	GLB1	ASAH1	RB1	CDKN1A	S1PR1	PLCB1	S1PR2	S1PR5	SPHK1	TERT	SPTLC1	GBA	MTOR	SGMS2	SMPD3	UGCG	KDSR	RPP38	CERS4	E2F1	SGPP1	DEGS1	CERS2	MAPK1	PRKCB	
BDNF TRKB SIGNALING%WIKIPATHWAYS_20260910%WP3676%HOMO SAPIENS	BDNF TrkB signaling	EIF4EBP1	NRAS	PLCG1	HRAS	GAB1	RPS6KA1	GAB2	ARC	RHEB	RPS6KB1	KRAS	EEF2K	BDNF	GRB2	DLG4	TRPC3	SOS1	SHC1-1	TRPC6	HOMER1	GRIN1	TSC2	CREB1	AKT1	MTOR	PIK3CG	TSC1	ADCY1	MKNK1	NTRK2	BRAF	MAP2K2;MAP2K1	MAPK1	
DIRECT REVERSAL REPAIR%WIKIPATHWAYS_20260910%WP4931%HOMO SAPIENS	Direct reversal repair	MGMT	ALKBH3	ALKBH2	
VASOPRESSIN REGULATED WATER REABSORPTION%WIKIPATHWAYS_20260910%WP5085%HOMO SAPIENS	Vasopressin regulated water reabsorption	ARHGDIB	ADCY3	VAMP2	STX4	RAB5A	GNAS-1	DCTN6	DCTN4	CREB3L3	CREB3L4	DYNC2H1	CREB5	CREB3L1	DYNC1H1	DYNC1I2	PRKACB-1	RAB11B	ADCY6	CREB3L2	DYNC2LI1	PRKACA-1	AVPR2	DCTN1	DYNC1LI1	DYNC1LI2	RAB5B	CREB1	RAB5C	ARHGDIA	ADCY9	DYNC1I1	AVP	ARHGDIG	NSF	CREB3	DCTN5	DCTN2	AQP4	RAB11A	AQP2	AQP3	
KLEEFSTRA SYNDROME%WIKIPATHWAYS_20260910%WP5351%HOMO SAPIENS	Kleefstra syndrome	SMARCD1	H3-3A	SMARCD2	SMARCD3	DPY30	RBBP5	PAXIP1	WDR5	KDM6A	KMT2C	SMARCC1	RXRA	MBD5	SMARCC2	NCOA6	ACTL6A	ARID1B	ASXL1	BAP1	SMARCB1	NR1I3	SMARCA2	ASH2L	ARID1A	SMARCA4	ACTL6B	PAGR1	EHMT1	
RUBINSTEIN TAYBI SYNDROME 1%WIKIPATHWAYS_20260910%WP5367%HOMO SAPIENS	Rubinstein Taybi syndrome 1	NPAS2	POLR1E	CREBBP	CREB1	DDX21	NCOA3	FBL	IRF2	ALX1	MAFG	PCNA	CLOCK	SMAD4	FOXO1-1	ARNTL	
IL19 SIGNALING%WIKIPATHWAYS_20260910%WP5422%HOMO SAPIENS	IL19 signaling	MAPK3	JAK1	MAPK8	COL1A1	STAT1	MAPK14	STAT3	MMP1	TNFRSF1A	IL20RA	IL20RB	IL19	MUC5AC	CXCR4	SOCS5	CCL11	IL4	TNF	AKT1	CCNB1	SOCS1	ACTA2	STAT6	IL4R	TGFB1	NFKB1	MAPK1	RAC1	
PLURIPOTENT STEM CELL DIFFERENTIATION PATHWAY%WIKIPATHWAYS_20260910%WP2848%HOMO SAPIENS	Pluripotent stem cell differentiation pathway	BMP4	IL6R	DKK1	NOTCH1	TPO	WNT7B	NODAL	WNT1	WNT2	HGF	TF	IL6	NTF4	TNFSF11	FLT3LG	GDF5	ALK	INS;INS-IGF2	EGF	EPO	PDGFA	KITLG	WNT3A	WNT5A	CNTF	FGF10	PDGFB	WNT2B	FST	FGF2	LEFTY2;LEFTY1	IL11	NOG	SHH	CSF1R	FGF1	IL3	CSF1	FGF4	INHBA	FGF8	CXCR1	VEGFA	KIT	TGFB1	TGFB3	NT5E	IGF1	
CREATINE PATHWAY%WIKIPATHWAYS_20260910%WP5190%HOMO SAPIENS	Creatine pathway	GATM	CKB	GAMT	OAT	SLC6A8	
CANCER PATHWAYS%WIKIPATHWAYS_20260910%WP5434%HOMO SAPIENS	Cancer pathways	ADCY8	RXRA	STAT5A	EGF	FN1	PRKACB-1	ESR1	TXNRD3	CCND1	MYC	RUNX1	ERBB2	HHIP	GNAI3	PDGFB	GNAI2	RPS6KA5	PTCH2	GLI2	SHH	KIF7	IGF1	BMP4	BMP2	MAPK8	CASP8	FADD	TPM3	GSTT2B;GSTT2	GSTM1;GSTM2-1	TGFBR1-1	MMP3	GSTA3;GSTA1	GSTA3;GSTA5;GSTA1;GSTA2	IL13RA1	FZD1	FZD3	WNT3A	WNT5A	WNT7A	WNT3	LRP6	AKT2	AKT3	AKT1	MTOR	AGTR1	GSK3B	HDAC1	PIK3R2	PIK3R1	MAP2K2;MAP2K1	MAPK1	EPAS1	RAC1	JAK2	LPAR2	LPAR3	IL6R	LPAR4	GNG10	MAPK3	JAK1	NCOA1	GNG13	CREBBP	STAT1	TXNRD1	LPAR5	BAD	LPAR6	SPI1	STAT3	GNGT1	AGT	MMP1	IKBKG	RUNX1T1	KEAP1	IL6	IGF1R	RPS6KB1	FRAT2	GRB2	SKP1	IL6ST	SOS1	BCL2L1	VEGFB	VEGFD	TCF7	DVL1	CXCL8	DVL2	KITLG	DVL3	CSF3R	IL2	ESR2	IL4	IFNG	SP1	PDGFRA	F2R	FLT4	IL12A	COL4A2	PTEN	COL4A1	BRCA2	COL4A4	POLK	FZD10	APC2	COL4A6	NCOA3	FGF1	CSF1R	AXIN1	SOS2	LEF1	EGFR	HSP90B1	E2F2	HES1	E2F3	PRKCG	BAK1	HES5	TCF7L2	TCF7L1	KLK3;KLK2	WNT5B	PRKCB	HEYL	GNB2	APC	PRKCA	GNB1	RPS6KB2	GNB4	SMO	GNB3	IL7R	NOTCH2	NOTCH3	NOTCH1	HSP90AB1	LAMC3	NOTCH4	LAMC2	PIK3R3	LAMC1	HSP90AA1	WNT6	WNT1	WNT2	WNT4	JAG2	MST1	WNT10B	WNT10A	IL3RA	CXCR4	SMAD4	FZD2	CXCL12	JAG1	LAMA5	FZD5	LAMA2	FZD4	TRAF3	LAMA1	FZD7	CCDC6	LAMA4	PTCH1	LAMA3	FZD6	FZD9	STAT4	SMAD2;SMAD3	FZD8	GNG2	IL12RB1	GNG5	IL12RB2	IFNGR1	FGFR4	GNG4	GNG8	FGFR3	IL23A	FGFR2	LAMB3	FGFR1	LAMB2	WNT2B	LAMB1	BCL2L11	PIK3CD	EPOR	PIK3CB	GLI3	FASLG	HEY1	HEY2	WNT9B	WNT9A	CDKN2A	WNT16	PIK3CA	PPARG	RASSF1	LRP5	WNT8A	PGF	WNT8B	DLL1	DLL3	DLL4	MAPK9	WNT11	WNT7B	MAPK10	PPARD	CTNNB1	RB1	CDKN1A	CDKN1B	BBC3	GLI1	FLT3LG	CASP9	TFG	CCND3	DAPK2	CCND2	DAPK3	EML4	CASP3	MECOM	APPL1	FH	MAX	NKX3-1	PLEKHG5	APAF1	TRAF4	CCDC42	BIRC7	BIRC2	BIRC3	DDB2	RASSF5	RALGDS	CCNE2	RASGRP2	CSF2RA	RASGRP4	CCNE1	PLD2	RASGRP3	TP53	GNB5	MDM2-2	CKS1B	CYCS-1	ARHGEF11	ARHGEF12	DCC	DAPK1-1	ABL1	RALB	ADCY1	E2F1	LAMB4	RBX1	PMAIP1	MSH6	BID	CTBP2	MSH2	GADD45B	MSH3	GADD45A	PML	GADD45G	CDK6	ARNT2	RAD51	CDK4	CDK2	FAS	BAX	FOXO1-1	FLT3	IL2RG	STAT6	TGFB2	IL4R	TGFB1	ARNT	TGFB3	NFKB1	MLH1	NFKB2	TGFBR2	TRAF6	IL2RA	IL2RB	GNA11	NTRK1	IL12B	RET	EDN1	HGF	MMP2	IL13	IL5RA	CSF2RB	PLD1	CCNA1	VHL	PDGFA	TGFA	TERT	HMOX1	CDKN2B	IL5	NFE2L2	PTGER4	PTGER2	CASP7	VEGFA	EDNRA	EDNRB	PTGER1	PTGER3	ADCY3	CAMK2B	GNAI1	CAMK2D	NRAS	IGF2	HIF1A	CAMK2A	HRAS	CAMK2G	RALBP1-1	GNAS-1	RALA-1	GNAQ	KRAS	PTGS2-2	BDKRB2	ALK	ETS1	CRKL	MET	COL4A3	COL4A5	F2RL3	ELK1	IKBKB	EP300	JAK3	CHUK	FOS	CEBPA	CBL	RELA	CALML6	CALML3	CALML4	STAT5B	NFKBIA	EPO	PDGFRB	AXIN2	KIT	CTBP1	EGLN1	EGLN3	EGLN2	PLCB3	PLCB4	PLCB1	PLCB2	JUN	BCL2	RXRB	RAF1	RXRG	MGST3	MGST1	MGST2	NCOA4	AR	GSTM4	GSTM3	TRAF2	ADCY4	ADCY2	ADCY7	ADCY6	NOS2	ADCY5	ADCY9	GSTO2	GSTO1	GNA13	GNA12	ARHGEF1	BCR	PIM2	GSTP1	RASGRP1	KNG1	XIAP	TRAF1	GSTA4	ITGA2B	ARAF	BIRC5	BDKRB1	BRAF	PTK2	PIM1	ITGB1	CUL2	RAC3	ITGAV	ELOC-1	ITGA3	ITGA2	ELOB	JUP	ZBTB16	ITGA6	SKP2	CRK	ROCK1	ROCK2	CUL1	ZBTB17	IL15	IL3	CCNA2-1	IL7	HDAC2	TRAF5	CDH1	CTNNA1	CTNNA3	CTNNA2	IFNAR2	STAT2	IFNGR2	IFNAR1	RARA	RARB	PLCG2	F2	TPR	MITF	TXNRD2	SLC2A1	LPAR1	PLCG1	RHOA	PRKACA-1	NQO1	VEGFC	PAX8	
FAMILIAL PARTIAL LIPODYSTROPHY%WIKIPATHWAYS_20260910%WP5102%HOMO SAPIENS	Familial partial lipodystrophy	MAPK9	ICMT	LMNA	ZMPSTE24	KLF9	SREBF1	LMNB1	FNTA	CEBPA	PNPLA2	INS;INS-IGF2	STAT5B	LIPE	BANF1	FABP4	AKT2	GATA3	GATA2	KLF2	KLF5	PPARA	PRRX1	CIDEA	CIDEC	PIK3CA	PPARG	LMNB2	LPL	PLIN1	MGLL	
BDNF SIGNALING IN NEURODEVELOPMENT%WIKIPATHWAYS_20260910%WP5541%HOMO SAPIENS	BDNF signaling in neurodevelopment	MAPK7	IKBKB	PDPK1	MAPK11	CTNNB1	CHUK	RAPGEF1	CASP9	CRK	NFKBIA	ROCK1	ROCK2	CDC42	PAK1	MYC	APAF1	DOCK7	CREB1	ARHGDIA	YWHAE	TP53	YWHAB	YWHAQ	CYCS-1	YWHAH	MKNK1	SMPD1	MAP3K3	ARHGAP35	TIAM2	PARD3	IQGAP3	NPTX2	WASL	RND3	PARD6B	LINGO1	SORT1	MAPKAPK2	KIDINS220	MAPK8	CASP8	BAX	TRADD	FADD	MAP2K7	IRS1	EIF4E	IRS2	BDNF	EEF2K	JUN	MAP3K1	BCL2	EEF2	RAF1	AKT1	MAP3K5	MTOR	GSK3B	YWHAG	YWHAZ	MAP2K2;MAP2K1	MAPK1	RAC1	EIF4EBP1	TRAF6	MAPK3	NGFR	MAP2K4	BAD	PRKCD	STAT3	GAB1	PTPN11	IKBKG	RTN4R	RPS6KB1	GRB2	SOS1	SHC1-1	TCF7	SH2B2	CFL1	BMP7	LEF1	PRKCG	PRKCI	TCF7L2	PRKCH	TCF7L1	PRKCB	PRKCE	PRKCA	RPS6KB2	NRAS	PLCG1	PRKCZ	HRAS	RHOA	KRAS	PARD6A	CFL2	STMN1	LIMK1	TIAM1	DIAPH1	FOXO3	BCL2L11	PIK3CD	PIK3CB	RAP1B	PIK3CG	TP73	FRS2	MAP2K5	NTRK2	PIK3CA	
REGULATION OF TOLL LIKE RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP1449%HOMO SAPIENS	Regulation of toll like receptor signaling	IRF3	MAPK9	CYLD	MAPK14	MAPK12	MAPK13	IKBKB	MAPK10	MAPK11	CHUK	FOS	RELA	NFKBIA	PTPN6	PLK1	TNF	IFNB1-4	IRAK1	IRAK2	MAP3K8	TOLLIP	TAB3	CXCL11	TAB2	TAB1	MYD88	IL1B	USP7	FBXW5	CD180	TRAFD1	RNF41	MAPK8	SIGIRR	RBCK1	CASP8	LY96	RNF216	CUEDC2	SFTPD	RIPK1	IRAK3	FADD	MBL2-1	TICAM1	PELI1	ZMYND11	RNF31	MAP2K7	PELI3	PELI2	CTNNAL1	MAP2K6	SARM1	MAP2K3	JUN	IFNAR2	CCL5	AKT2	AKT3	CD86	AKT1	TMED7	CD80	IFNAR1	SOCS1	CISH	PIK3R2	PIK3R1	IRAK4	NFKB1	MAP2K2;MAP2K1	NFKB2	MAPK1	RAC1	CXCL10	TRAF6	MAP3K7	MAPK3	MAP2K4	STAT1	IL12B	IKBKG	LBP	IL6	CCL3L1;CCL3L3;CCL3;CCL18	SYK	BTK	CXCL8	CCL4L2;CCL4L1;CCL4	TICAM2	SPP1	TIRAP	TLR1	TLR9	TLR8	TLR6	IL12A	TLR7	TLR4	TLR3	CXCL9	IRF7	SQSTM1	PIK3R3	CD14	PIK3R5	TRAF3	CD40	TIFA	TNFAIP3	TREM1	TLR5	TLR2	MLST8	PIK3CD	PIK3CB	PIK3CG	IRF5	SMAD6	TBK1	OTUD5	PIK3CA	IKBKE	
ALTERED GLYCOSYLATION OF MUC1 IN TUMOR MICROENVIRONMENT%WIKIPATHWAYS_20260910%WP4480%HOMO SAPIENS	Altered glycosylation of MUC1 in tumor microenvironment	CHUK	IKBKG	IL6	RELA	MUC1	NFKBIA	TNF	NFKB1	IKBKB	
NUCLEOTIDE GPCRS%WIKIPATHWAYS_20260910%WP80%HOMO SAPIENS	Nucleotide GPCRs	P2RY6	LPAR4	ADORA1	P2RY4	ADORA2B	P2RY2	ADORA3	P2RY1	LPAR6	LTB4R	ADORA2A	
OVERVIEW OF NANOPARTICLE EFFECTS%WIKIPATHWAYS_20260910%WP3287%HOMO SAPIENS	Overview of nanoparticle effects	CDH3	PTGS1	HMOX1	BAX	COL4A1	PIK3CD	TNF	AKT3	ITGAD	IL6	CRP	PTGS2-2	PTK2	NFRKB	CCND3	LAMA3	FN1	BCL2	CXCL8	
NEURAL CREST CELL MIGRATION DURING DEVELOPMENT%WIKIPATHWAYS_20260910%WP4564%HOMO SAPIENS	Neural crest cell migration during development	NGFR	CDH11	PIK3R4	PIK3R3	STAT3	PIK3R6	PIK3R5	RHOA	FOS	MMP2	BDNF	TRIO	JUN	MMP9	EPHB6	EPHB1	EPHB3	NGEF	MMP8	BUB1B-PAK6;PAK6	PAK1	PAK5	PAK3	PAK2	PAK4	TIAM1	EPHB2	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	EPHB4	F2RL2	PIK3CG	PIK3CA	ARF1	RAC1	
METABOLIC REPROGRAMMING IN PANCREATIC CANCER%WIKIPATHWAYS_20260910%WP5220%HOMO SAPIENS	Metabolic reprogramming in pancreatic cancer	GOT1-1	SLC2A1	SLC1A5	HK2	BCKDHA	GLS2	LDHA	PKM	HK1	SLC16A1	GLUD1;GLUD2	DLAT	SLC7A5	KRAS	CARM1	DLD	UAP1	PDHB	BCAT2	FASN	SLC43A1	LDLR	PDHX	ME1	PGM3	HMGCS2	SLC16A4	GPT	RPIA	PFKL	SOAT1	PDHA1	RPE;RPEL1	ACLY	GNPNAT1	TP53	GFPT1	HMGCR	CS	MDH1	GOT2-1	GPI	
LDL INFLUENCE ON CD14 AND TLR4%WIKIPATHWAYS_20260910%WP5272%HOMO SAPIENS	LDL influence on CD14 and TLR4	CREB3L2	IL1B	CREB1	MAPK14	CD14	MAPK12	TLR4	MAPK13	ATF4	MAPK11	CCL13;CCL2	IL6	REL	RELA	CREB3	CREB3L3	RELB	CREB3L4	CREB5	CREB3L1	IL10	NFKB1	NFKB2	
LEPTIN AND ADIPONECTIN%WIKIPATHWAYS_20260910%WP3934%HOMO SAPIENS	Leptin and adiponectin	PRKAB1	PRKAA1	ADIPOQ	LEPR	ACACA	PRKAG1	ADIPOR1	ADIPOR2	LEP	CPT1A	
SELENIUM MICRONUTRIENT NETWORK%WIKIPATHWAYS_20260910%WP15%HOMO SAPIENS	Selenium micronutrient network	SCARB1	SERPINA3	SERPINE1	PLAT	FLAD1	TXNRD1	MTR-1	RFK	MPO	GPX6	ICAM1	SAA2;SAA1	CBS;CBSL	FGB	PRDX1	FGA	SAA2-SAA4;SAA4	FGG	IL6	APOA1	F2	RELA	F7	PLG	HBD;HBB	LDLR	ABCA1	TXNRD3	INSR	MTHFR	SOD2	SOD3	SOD1	IFNG	HBA2;HBA1	CTH	ALB	TNF	PNPO	KMO	CAT	XDH	KYNU	TXNRD2	IL1B	PTGS1	ALOX5	ALOX15B	ALOX5AP	GPX1	GPX4	PTGS2-2	GSR	INS;INS-IGF2	APOB	GGT1	SEPHS2	SELENOO	SELENON	SELENOS	SELENOT	SELENOK	SELENOI	PRDX3	SELENOP	PRDX2	PRDX5	PRDX4	DIO1	DIO3	CCL13;CCL2	CRP	NFKB1	TXN	NFKB2	
ATOPIC DERMATITIS MECHANISM AND THERAPIES%WIKIPATHWAYS_20260910%WP5538%HOMO SAPIENS	Atopic dermatitis mechanism and therapies	IL1RL1	IL13RA1	IL4	STAT3	IL33	TSLP	IL5	FCER1G	TYK2	IL31RA	JAK3	FCER1A	DEFB103A;DEFB103B	IL2RG	MS4A2	OSMR	CRLF2	STAT6	IL13	IL4R	IL25	
VITAMIN D IN INFLAMMATORY DISEASES%WIKIPATHWAYS_20260910%WP4482%HOMO SAPIENS	Vitamin D in inflammatory diseases	SMAD2;SMAD3	PPP3CA	NFATC1	RXRA	MAPK14	TNF	MED14	VDR	IKBKB	DUSP1	CHUK	IKBKG	PPP3R1	IL6	SMAD4	RELA	MAP2K6	MAP2K3	NR3C1	MAP3K1	NFKBIA	NFKB1	
1Q21 1 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP4905%HOMO SAPIENS	1q21 1 copy number variation syndrome	TJP3	TJP2	PRKAA1	CTNNB1	TJP1	GJA1	FMO5	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PRKAB2	PRKAB1	F11R	GJA3	KIRREL1	AMELY;AMELX	ACP6	GJA5	OCLN-1	GJA8	CHD1L	PYGO1	PYGO2	BCL9	AFDN	
CELL DIFFERENTIATION EXPANDED INDEX%WIKIPATHWAYS_20260910%WP2023%HOMO SAPIENS	Cell differentiation expanded index	RUNX2	MEF2A	MEF2B;BORCS8-MEF2B	KLF4	TLX3	TLX2	MEF2D	PAX7	ID2-1	TLX1	LEFTY2;LEFTY1	STAT3	EZH2	HDAC5	SOX2	MEF2C	MYOD1	SRF	
PATHWAYS OF NUCLEIC ACID METABOLISM AND INNATE IMMUNE SENSING%WIKIPATHWAYS_20260910%WP4705%HOMO SAPIENS	Pathways of nucleic acid metabolism and innate immune sensing	IRF3	RNASEH2C	RNASEH2B	RNASEH2A	MAVS	TREX1	RNASEL	RNASET2	STING1	ADAR	SAMHD1	IFNB1-4	OAS1	CGAS	IFIH1	DDX58	
CELIAC DISEASE MECHANISM AND THERAPIES%WIKIPATHWAYS_20260910%WP5562%HOMO SAPIENS	Celiac disease mechanism and therapies	IL2	F2RL1	IFNG	ITGB7	ITGA4	TNF	DHODH	IL15	CD4	EGFR	IL21	GZMH;GZMB-1	TGM2	
METABOLIC REPROGRAMMING IN COLON CANCER%WIKIPATHWAYS_20260910%WP4290%HOMO SAPIENS	Metabolic reprogramming in colon cancer	SLC2A1	SLC1A5	PYCR2	LDHA	GLS	GAPDH-1	PGAM1	PKM	PGK1	ENO1	PSPH	HK3	PYCR1	SLC16A3	IDH3A	IDH2	TIGAR	TALDO1	PAICS	GLUD1;GLUD2	G6PD	ACO2	TKT	PSAT1	SHMT2	PDHB	SDHB	FASN	FH	DLST	RPIA	PFKL	ALDOB	PDHA1	ACLY	SUCLG2	MDH2	GOT2-1	GPI	PGD	
NEURODEGENERATION WITH BRAIN IRON ACCUMULATION NBIA SUBTYPES PATHWAY%WIKIPATHWAYS_20260910%WP4577%HOMO SAPIENS	Neurodegeneration with brain iron accumulation NBIA subtypes pathway	DEPTOR	ATG16L1	PLA2G6	PRKAA1	MECP2	ATG101	FTL-1	PIK3R4	RHEB	WDR45	RB1CC1	DCAF17	C19orf12	ACACA	WIPI1	GTPBP2	WIPI2	CP	COASY	FA2H	BECN1	ATP13A2	RPTOR	STK11	ATG14	ATG13	TSC2	SCP2	MLST8	ULK1	SPTLC1	MTOR	MAP1LC3A	TSC1	ATG3	ATG10	ATG12-1	ATG2A	AKT1S1	PIK3C3	ATG4A	ATG7	ATG5	
HIPPOCAMPAL SYNAPTOGENESIS AND NEUROGENESIS%WIKIPATHWAYS_20260910%WP5231%HOMO SAPIENS	Hippocampal synaptogenesis and neurogenesis	PRKCA	CAMK2B	CAMK2A	NRXN3	NRXN2	MAPK14	PPARGC1A	RPS6KA1	NRXN1;NRXN3;NRXN2	NGF	BDNF	CAMKK2	CCND2	HNRNPL	BCL2	CAMKK1	SYT2	SYT12	DRD1	CREB1	RPS6KA5	CAMK4	PRL	NCAM1	CALM1	MAPK1	
CONVERSION OF ANGIOTENSINOGEN TO ANGIOTENSIN II %WIKIPATHWAYS_20260910%WP4818%HOMO SAPIENS	Conversion of angiotensinogen to angiotensin II	CTSG	ACE	CTSD	CMA1	REN	
MIR TARGETED GENES IN LEUKOCYTES%WIKIPATHWAYS_20260910%WP2003%HOMO SAPIENS	miR targeted genes in leukocytes	WDR11	LAMTOR3	TUSC2	PKM	ARID4B	MAPK14	CTNNB1	WDFY1	MATR3	SLC1A4	CORO1C	RAB6A	ANAPC1	CD164	SLC25A1	SNAP23	TNFAIP2	TMEM109	ACP2	SCYL1	GNAI2	ARHGDIA	RFT1	YWHAQ	MAP3K8	PDLIM5	CDK6	TUBA1A	ACAA2	ARF4-1	ZEB1	SRSF10	CDIPT	ANXA2	TPM3	G6PD	GOLGA7-1	TNFSF9	IDH1	RAB34	TMED10	ADIPOR2	MRPL20	BCL2	ANPEP	DDX5	ATP6V1F	TBCA	HNRNPM	TRAM1	ADAR	RDH10	MRC2	SPTLC1	SH3BGRL3	USP1	SEC24A	PPIF	CAPG	PRPF40A	POM121;POM121C	PPIB	PNP-1	POLE4	IFRD1	DNAJB1	POLR2C	RTN4	TXNRD1	CAP1	PHC2	AP3D1	ARCN1	IGF2R	CSRP1	FMNL2	GYS1	ATP6V0E2;ATP6V0E1	PLXND1	SLC7A11	ATP2A2	TXN2	CEBPB	SERPINE2	C1orf56	DCAF7	KCNN4	TMEM43	SAC3D1	HMOX1	ADPGK	PRSS21	PTRH1	UNC93B1	GNA13	NELFCD	MCL1	TYMS	CHORDC1	CDK5RAP1	MTHFD2	VPS39	CDK5RAP3	ATP6V0A1	SNX6	SFXN1	PTPA	FADS1	RAB5C	PISD	TMED3	CTSC	BCL6	RHOG	GAK	THBS1	SLC7A6	CDCP1	FRG1	BRPF3-1	MPDU1	LMNB2	LPL	SHOC2	CA12	
TARGETED THERAPY IN BREAST CANCER%WIKIPATHWAYS_20260910%WP5496%HOMO SAPIENS	Targeted therapy in breast cancer	MAPK3	NRAS	PIK3R4	ERBB3	PIK3R3	ERBB4	HRAS	PIK3R6	PIK3R5	KRAS	RAF1	ERBB2	PIK3CD	AKT2	PIK3C2G	AKT3	PIK3CB	AKT1	PIK3C2A	PIK3CG	PIK3C2B	EGFR	PIK3R2	PIK3R1	PIK3CA	MAPK1	
MICROGLIA PATHOGEN PHAGOCYTOSIS PATHWAY%WIKIPATHWAYS_20260910%WP3937%HOMO SAPIENS	Microglia pathogen phagocytosis pathway	ITGB2	C1QC	RAC3	PLCG2	PIK3R3	VAV3	PIK3R6	FCGR1A	VAV1	VAV2	HCK	NCF2	TREM2	LYN	SYK	PTPN6	C1QB	TREM1	NCF1	TYROBP	LAT	ARPC1B	NCF4	PIK3CD	SIGLEC9;SIGLEC7;SIGLEC8;SIGLEC12-1	CYBA	PIK3CB	FCER1G	PIK3C2A	PIK3CG	CYBB	PIK3R2	PIK3R1	PIK3CA	NCKAP1L	PIK3C3	ITGAM	RAC1	
STATIN INHIBITION OF CHOLESTEROL PRODUCTION%WIKIPATHWAYS_20260910%WP430%HOMO SAPIENS	Statin inhibition of cholesterol production	APOA4	APOA5	LIPC	APOC2	SCARB1	CYP7A1	PLTP	FDFT1	APOA1	MTTP	APOE	APOB	LDLR	ABCG8	ABCA1	ABCG5	SQLE	APOC3	SOAT1	DGAT1	ACSS1	APOC1	PDIA2	HMGCR	CETP	LRP1	APOA2	LPL	LCAT	
PATHWAYS AFFECTED IN ADENOID CYSTIC CARCINOMA%WIKIPATHWAYS_20260910%WP3651%HOMO SAPIENS	Pathways affected in adenoid cystic carcinoma	KDM6A	CREBBP	ARID4B	EP300	SMARCE1	CEBPA	BRCA1	CHEK2	CHEK1	MAX	TLK1	MYC	ERBB2	SMC1A	ARID5B	FGF16	PTEN	ARID1A	TP53	JMJD1C	MYB	NCOR1	MYBL1	CMTR2	UHRF1	MAGI1	BRD1	INSRR	IL17RD	MORF4L1-2	FOXP2	MYCN	KAT6A	CTBP1	MAML3	DTX4	FBXW7	CNTN6	MGA	MYCBP-1	H2AC16;H2AC11	H1-4	KANSL1	NFIB	NOTCH1	KMT2C	PRKDC	KDM6B	HRAS	ATM	BCOR	SRCAP	RAF1	NSD1	FGFR4	SMARCA2	ERBIN	FOXO3	AKT1	BCORL1	ATRX	MAGI2	PIK3CA	MAP2K2;MAP2K1	SETD2	
NEPHROTOXCICITY ADVERSE OUTCOME PATHWAY%WIKIPATHWAYS_20260910%WP5229%HOMO SAPIENS	Nephrotoxcicity adverse outcome pathway	SLC22A2	SLC31A1	
HEART DEVELOPMENT%WIKIPATHWAYS_20260910%WP1591%HOMO SAPIENS	Heart development	BMP4	BMP2	GATA6	TBX20	BMP10	NKX2-5	NOTCH1	IRX4	TBX2	HAND2	TBX5	ERBB3	FOXC2	FOXC1	PITX2	PTPN11	GATA4	HAND1	NFATC2	CTNNB1	SMAD1	SMAD4	VEGFB	FOXA2	SMYD1	TBX1	NFATC1	BMPR1A	FGF10	BMPR2	FOXH1	SHH	BHLHE40	HEY1	VEGFC	HEY2	FGF8	VEGFA	MEF2C	NFATC3	ISL1	NFATC4	MAPK1	SRF	
NANOMATERIAL INDUCED INFLAMMASOME ACTIVATION%WIKIPATHWAYS_20260910%WP3890%HOMO SAPIENS	Nanomaterial induced inflammasome activation	IL1B	PYCARD	CASP1	CTSB	TLR4	NFKB1	NOX1	
MACROPHAGE MARKERS%WIKIPATHWAYS_20260910%WP4146%HOMO SAPIENS	Macrophage markers	CD68	F3	CD74	CD163	CD14	CD83	LYZ-1	CD86	
CYSTEINE AND METHIONINE CATABOLISM%WIKIPATHWAYS_20260910%WP4504%HOMO SAPIENS	Cysteine and methionine catabolism	GOT1-1	CSAD	AHCY	MTR-1	CTH	CDO1	MPST	SQOR	CBS;CBSL	SUOX	BHMT	ETHE1	MAT1A	GSS	GCLC	
SIGNAL TRANSDUCTION THROUGH IL1R%WIKIPATHWAYS_20260910%WP4496%HOMO SAPIENS	Signal transduction through IL1R	MYD88	TRAF6	MAP3K7	IL1B	MAPK8	MAPK14	IKBKB	IRAK3	CHUK	IL1RN	IL6	RELA	MAP2K6	MAP2K3	JUN	MAP3K1	NFKBIA	IL1A	IL1R1	ECSIT	TNF	IFNB1-4	IL1RAP	IRAK1	IRAK2	TGFB2	TGFB1	TGFB3	TOLLIP	NFKB1	TAB1	MAP3K14	
TRANSLATION FACTORS%WIKIPATHWAYS_20260910%WP107%HOMO SAPIENS	Translation factors	EIF4EBP1	EEF1A1	PAIP1	EIF4EBP2	EIF2S1	EIF2S2	EIF4G1	EIF2S3;EIF2S3B	EIF1	EIF4A2	EIF3C;EIF3CL	GSPT2	EIF5	EIF4H	EIF4E	EIF3I	EIF2B1	EIF1AY;EIF1AX	EEF2K	EEF1B2-1	EIF3J	EIF2B5	EIF3G	EIF2B4	EIF3H	EIF5B	EIF3E	EIF2B3	EIF3F	CLUH	EIF3D	EIF5A;EIF5AL1	EIF3A	EEF1G	EIF3B	EEF2	EIF6	EEF1D	EIF2B2	EEF1A2	ETF1	PABPC1;PABPC3	EIF4G3	EIF4B	EIF2AK1	EIF2AK3	EIF2AK2	EIF4A1	
BRAIN DERIVED NEUROTROPHIC FACTOR BDNF SIGNALING%WIKIPATHWAYS_20260910%WP2380%HOMO SAPIENS	Brain derived neurotrophic factor BDNF signaling	MAPK9	MAPK7	PRKAA1	MAPK14	VAV3	ELK1	IKBKB	PDPK1	MAPK10	EIF2S2	CTNNB1	CHUK	VAV2	RELA	PRKAA2	STAT5A	STAT5B	NFKBIA	CASP3	SRC	CDC42	CREB1	RAB3A	YBX1	RPS6KA5	CAMK1	NSF	IGF2BP1	GRIN2B	RASGRF1	LINGO1	SORT1	CDK5	KIDINS220	GRIA3	MAPK8	CRTC1	RPS6KA3	RPS6KA1	MAPT	IRS1	EIF4E	IRS2	BDNF	NCF2	JUN	MAP3K1	ACACB	PPP2CB;PPP2CA	EEF2	RAF1	CDKL5	GRIN1	TSC2	CDK5R1	SYN1	FYN	AKT1	MTOR	ADAM17	GSK3B	RPS6	PIK3R2	PIK3R1	NFKB1	MAP2K2;MAP2K1	MAPK1	SIRPA;SIRPB1;SIRPG	RAC1	JAK2	EIF4EBP1	RACK1	TRAF6	MEF2A	NCK2	MAPK3	NGFR	MAP3K2	STAT1	NTRK1	BAD	PRKCD	NTRK3	STAT3	EIF2S1	PTPN11	IKBKG	CDH2	RPS6KB1	GRB2	SHC4	SHC1-1	SHC2	SH2B2	CFL1	NCF1	CSNK2A1;CSNK2A3	PTK2B	GABRB3	MEF2C	SQSTM1	NFATC4	APC	GRIP1	CYFIP1	GRIA1	PLCG1	CAMK2A	GRIA2	HRAS	NGF	DLG1	CNR1	NCK1	DPYSL2	FRS3	DOK5	KCNN2	TIAM1	DOCK3	KCNA3	PTPRF	NTF3	SH2B1	RANBP9	FOXO3	MARCKS	CAMK4	SHC3	RHOG	RAP1A	FRS2	MAP2K5	KSR1	NCAM1	NTRK2	
ROS IN COVID 19 ENDOTHELIAL DYSFUNCTION%WIKIPATHWAYS_20260910%WP5258%HOMO SAPIENS	ROS in COVID 19 endothelial dysfunction	ACE2	IFNAR1	TNFRSF1A	ICAM1	TNF	NFKB1	NOX1	
DICLOFENAC METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP2491%HOMO SAPIENS	Diclofenac metabolic pathway	CYP2C18-1	CYP2B6	CYP2C9;CYP2C19	
SREBF AND MIR33 IN CHOLESTEROL AND LIPID HOMEOSTASIS%WIKIPATHWAYS_20260910%WP2011%HOMO SAPIENS	SREBF and miR33 in cholesterol and lipid homeostasis	MED15	NR1H3	SREBF2	PRKAA1	SCD	PPARGC1A	SIRT1	MTOR	HMGCR	HMGCS1-1	SREBF1	SIRT6	PPARA	FASN	LDLR	ABCA1	
ENTEROHEPATIC CIRCULATION OF BILE ACIDS%WIKIPATHWAYS_20260910%WP5396%HOMO SAPIENS	Enterohepatic circulation of bile acids	ABCC3	SLC51A	SLC51B	ABCC4	SLC10A1	ABCC2	ABCB11	SLC10A2	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	FABP6	ABCB1	
NOTCH SIGNALING%WIKIPATHWAYS_20260910%WP61%HOMO SAPIENS	Notch signaling	JAK2	DLL1	PSEN1	DLL3	DLL4	NCOR2	SNW1	STAT3	EP300	NUMB	NUMBL	SKP1	SRC	CUL1	ITCH	APH1A	RBPJ	NCSTN	NCOR1	APH1B	FHL1	HES1	HES6	HES5	MAML3	FBXW7	TLE1	HDAC2	NOTCH2	NOTCH3	NOTCH1	PSENEN	NOTCH4	JAG2	JAG1	LCK	MAML2	MAML1	AKT1	CIR1	MTOR	RING1	SAP30	DTX1	ADAM17	MAGEA4;MAGEA1;MAGEA3;MAGEA2;MAGEA2B;MAGEA12;MAGEA6;MAGEA10-MAGEA5;MAGEA5;MAGEA9B;MAGEA9;MAGEA8;MAGEA11	HEY2	SPEN	GSK3B	HDAC1	PIK3R2	PIK3R1	PSEN2	NFKB1	
GLP 1 IN PANCREATIC ISLET CELLS%WIKIPATHWAYS_20260910%WP5447%HOMO SAPIENS	GLP 1 in pancreatic islet cells	SLC2A1	GCG	IL6R	IL6	GLP1R	SLC2A2	INS;INS-IGF2	
DEVELOPMENT OF PULMONARY DENDRITIC CELLS AND MACROPHAGE SUBSETS%WIKIPATHWAYS_20260910%WP3892%HOMO SAPIENS	Development of pulmonary dendritic cells and macrophage subsets	TCF4	RUNX2	CSF2	TPO	ID2-1	SPI1	STAT3	CSF1	IRF4	IRF8	BATF3	FLT3LG	IKZF1	
P38 MAPK SIGNALING%WIKIPATHWAYS_20260910%WP400%HOMO SAPIENS	p38 MAPK signaling	RASGRF1	MAP3K7	MAPKAPK2	MAP2K4	STAT1	MAPK14	ATF2	HRAS	TRADD	ELK1	PLA2G4A	RIPK1	MAP3K9	MAP2K6	GRB2	TRAF2	MAP3K1	TGFBR1-1	DDIT3	SHC1-1	MAX	CDC42	MYC	MEF2D	CREB1	RPS6KA5	MAP3K5	HSPB1	DAXX	MKNK1	TGFB2	HMGN1	MAPKAPK5	SMIM40	RAC1	
NETWORK MAP OF SARS COV 2 SIGNALING%WIKIPATHWAYS_20260910%WP5115%HOMO SAPIENS	Network map of SARS CoV 2 signaling	WDR74	SKAP1	CFP	BTN3A1;BTN3A3	APOM	APOH	HP;HPR	VPS11	TPO	VPS16	INTS4	TOMM70	HRG	CTSZ	UPF1	SDF2	GP1BA	ATP13A3-1	IL16	OS9	SERPINA5	SRP72	MIB1	FOS	LRG1	ACTG1	CCL27	RHEB	CCL26	RRM2-1	SRP19	STEAP3	CLCC1	TLE3	VPS33A	ADAM9	G3BP1	FN1	G3BP2	CFB	NPTX1	PTPN6	MDN1	FAM83A	NEK9	HSPA8	C1S	GGH	C1R	TP53I3	CFI	PF4;PF4V1-1	LGALS3BP	ATG13	TRO	SELP	LARP1-1	TRIM59	SRP54	ITIH4	ITIH3	ULK1	RAP1GDS1	FGF2	ERLEC1	TNF	CCL8	CXCL13	UGGT2	ATE1	C8A	ACTB-1	COL7A1	VPS41	FAM98A	CFH-3	IRAK1	CXCL2;CXCL3;CXCL1-1	CCL21	MYD88	IL1B	MAPK8	CASP8	CD226	CCL22	MMP25	EIF4E	JUN	BST2	IFITM3;IFITM2;IFITM1	LCK	CD8A	CD8B;CD8B2	MOV10	AKT1	MTOR	ACE2	SIGMAR1	CRP	DDIT4	GTF2F2	RAC1	JAK2	JUNB	JAK1	RTN4	STAT1	CD3G	PRG3	CD3E	DUSP1	CD2	NKRF	AGT	IKBKG	CD247	LBP	IL6	RRAS	TRAF2	IL10	CARD11	CCL11	CXCL8	IL18	IL4	IL1A	IFNG	IL12A	ITCH	IGFBP3	TLE1	PRKCQ	CD14	SMAD1	IL21	IL22	CXCL12	TRAF3	IL18RAP	SMAD5	BIRC5	IFI44L	IFIH1	TBK1	IGLL5;IGLL1	DDX58	IRF3	TRPM2	MAVS	CASP5;CASP4	TBKBP1	ITGA3	CASP9	EGR1	CASP3	APOD	CCR6	CCL1	IL33	CCL20	IFNB1-4	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	CD4	CCNB2	IL7	CCNB1	HLA-DRA	APOL3;APOL4;APOL1;APOL2	BID	CDK1	CCL23;CCL15	PARP2	ATP6AP1	NLRP1	CCL5	IFIT1	FYN	PIAS1	MX1-1	IRF9	CCL13;CCL2	CTSD	RPS6	ZAP70	NFKB2	TGFBR2	CXCL10	EIF4EBP1	TRAF6	SERPINE1	NTRK1	SAA2;SAA1	FGB	FGA	FGG	APOA1	IL13	CCL3L1;CCL3L3;CCL3;CCL18	HBD;HBB	CEBPB	C1QBP	CCL4L2;CCL4L1;CCL4	IL9	PMPCB	ALB	IL5	APOC1	CXCL9	IL1R2	AHR	PITRM1	MAP1LC3B2;MAP1LC3B-1	NLRP3	GABARAPL2	NFATC3	IL17A	DEPTOR	HIF1A	CTSB	CD163	GSN	EIF4A2	TF	PTGS2-2	CPN1	CTSV;CTSL	RPTOR	MARK2	CCR5	MLST8	CAMK4	CXCR1	CXCR2	TNFSF10	CXCL5;CXCL6	AKT1S1	GTSE1	APOA2	VPS36	VPS18	
ANDROGEN RECEPTOR NETWORK IN PROSTATE CANCER%WIKIPATHWAYS_20260910%WP2263%HOMO SAPIENS	Androgen receptor network in prostate cancer	SMARCD1	SMARCD2	SMARCD3	HSD17B2	SMARCC1	SMARCC2	ACTL6A	MAPK14	ARID1B	ELK1	RB1	CDKN1A	CDKN1B	FOS	MRE11	RHEB	RAPGEF1	BRCA1	ERG	CASP9	CDC25B	CRK	DOCK1	CHEK2	CASP3	CHEK1	CCND1	PAK1	MYC	CDC25A	PLK1	ARID1A	TP53	MDM2-2	F13B	SPINK1	FKBP5	BLM	BARD1	E2F1	NOXA1	MSH6	RICTOR	SPRY1	MSH2	RASA1	RAD50	CDK4	CDK2	CDK1	MAPK8	CASP8	BAX	ATM	SPRY2	ATR	HSD17B7	FOXA1	ABCC4	JUN	BCL2	RAF1	TSC2	SMARCA4	AKT1	MTOR	ETV4	MAP2K2;MAP2K1	MAPK1	EIF4EBP1	MAPK3	JAK1	AR	STAT1	BAD	STAT3	GAB1	PTPN11	MMP1	HGF	GRB2	SOS1	SP1	PTEN	CDKN2B	EIF4E1B	HSD17B4	HSD17B1	PTK2B	KLK3;KLK2	CYP17A1	PRKDC	HRAS	MAP4K1	CPN1	CRKL	SMAD2;SMAD3	RPTOR	ATF1	HSD17B3	HSD3B1;HSD3B2	ACTL6B	PXN	RAP1B	TSC1	RAP1A	NDRG1	CDKN2A	PIK3CA	
ENDODERM DIFFERENTIATION%WIKIPATHWAYS_20260910%WP2853%HOMO SAPIENS	Endoderm differentiation	GATA6	CEBPZ	VAV3	CTNNB1	HPRT1	APP	ZFHX4	NKX2-1	SESN1	ZBTB17	GLI2	HNF1B	PAX3	SOX17	CER1	CAND1	SFRP1	WWC1	TOX3	HOXA1	CTBP2	SFMBT1	CDYL	MAD2L2	RFX7	RAB38	NAA15	CTR9	TCF4	PRDM14	RTF1	ELK4	SIAH2	PBX1	FOXN3	DAB2	SP4	PAF1	TAF4B	LHX1	ONECUT1	HOXC11	CDC73	CRTC1	EZH2	HHEX	DUSP4	DUSP5	DUSP2	NME1	FOXA1	PAX9	BTAF1	LEO1	KDM4A	SOX2	LRPPRC	TNRC6C	NR3C1	MAP2K3	FOXO1-1	ACACA	FOXA2	PABPC1;PABPC3	SOX21	CEP250	RARG	DIP2A	WNT3	EOMES	WDHD1	ZNF281	PIAS1	EMSY	TOX	WDFY2	BCORL1	MBTD1	EPB41L5	UBR5	ATP8B2	PBX3	GDF3	TGFB1	TRERF1	NLK	NABP2	TRIM71	NCAPG2	PHF6	ZIC3	TRIM5	DKK1	JARID2	SLC2A12	TET1	STAT1	PARP8	TAF5	DDAH1	CUL4B	PLCH1	AEBP2	MTF2	GATA4	AHDC1	ASCC3	ZNF462	ELP4	OTX2	GRHL2	SOX7	RGS10	TCF7	C1QBP	BMP7	EXT1	LEF1	TCF7L1	APC	POU5F1;POU5F1B	NOTCH1	NANOG;NANOGP8	LAMC1	ELAVL1	DNMT3B	MIXL1	NODAL	BPTF	SMAD4	TBX21	SMAD2;SMAD3	BMPR1A	NOG	FOXH1	WNT8A	PTHLH	
SARS COV 2 B 1 1 7 VARIANT ANTAGONISES INNATE IMMUNE ACTIVATION%WIKIPATHWAYS_20260910%WP5116%HOMO SAPIENS	SARS CoV 2 B 1 1 7 variant antagonises innate immune activation	TRAF6	IRF3	TBK1	TOMM70	MAVS	TRAF3	IKBKE	IFNB1-4	DDX58	
7Q11 23 DISTAL COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5401%HOMO SAPIENS	7q11 23 distal copy number variation	SRRM3	RAF1	ZP2	LMNA	POR	PTPMT1	MDH2	HSPB1	YWHAG	TMEM120B	RHBDD2	ZP3;POMZP3	SFN	TMEM120A	SSC4D	DAPK2	STYXL1	G3BP1	KIF1C	ZP1	
EFFECTS OF NITRIC OXIDE%WIKIPATHWAYS_20260910%WP1995%HOMO SAPIENS	Effects of nitric oxide	NOS2	NOS1	HBA2;HBA1	NOS3	XDH	HBD;HBB	MB	AOX1	
NRF2 ARE REGULATION%WIKIPATHWAYS_20260910%WP4357%HOMO SAPIENS	NRF2 ARE regulation	PRKCA	PGAM5	GSTA3;GSTA5;GSTA1;GSTA2	GCLM	INSR	NQO1	HMOX1	MAPK8	MAF	FYN	EPHB2	YES1	NFE2L2	KEAP1	CUL3	SLC7A11	GSK3B	RBX1	PIK3CA	CEBPB	GCLC	SRC	AIMP2	
ROTENONE METABOLISM%WIKIPATHWAYS_20260910%WP5486%HOMO SAPIENS	Rotenone metabolism	CYP2C9;CYP2C19	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
GLUCOCORTICOID RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2880%HOMO SAPIENS	Glucocorticoid receptor pathway	S100P	CPEB4	ZIC2	ANKRD1	LRRC8A	ANGPTL4	RXRA	NR1I3	CDKN1C	NR1I2	SNAI2	CUL1	PDE4B	BIRC2	BIRC3	B3GNT5	IL11	CCL20	SLC19A2	SPRY1	GADD45B	POU5F1;POU5F1B	ETNK2	HSP90AA1	ALOX5AP	PTGS2-2	NR3C1	ACKR3-2	JUN	TNFAIP3	AKAP13	EPB41L4B	ARL5B	THBD	RGS2	ENC1	TNS4	SRGN	FGFBP1	DNER	EDN2	TSC22D3	SERPINB9	NAV3	ADGRF4	CDC42EP3	TGFBR3	SCNN1A	PMP2	MFGE8	CCL13;CCL2	PTGES3-1	BHLHE40	SLC26A2	ABHD2	PRRG4	FGD4	SEC14L1	GPR153	SERTAD2	STOM	AMIGO2	MGAM	PPP1R14C	CAVIN2	PLK2	DNAJC15	NFKB2	KTN1	
NICOTINE METABOLISM IN LIVER CELLS%WIKIPATHWAYS_20260910%WP1600%HOMO SAPIENS	Nicotine metabolism in liver cells	FMO3	CYP2B6	CYP2A13;CYP2A6;CYP2A7-1	AOX1	
FATTY ACID TRANSPORTERS%WIKIPATHWAYS_20260910%WP5061%HOMO SAPIENS	Fatty acid transporters	FABP2	FABP9	ACSL6	ACSL5	FABP1	FABP3	FABP5	FABP4	FABP7	ACSL1	ACSBG2	ACSBG1	SLC27A4	CD36	FABP6	ACSL3	ACSL4	
INHIBITORS OF METABOLISM IN MELANOMA THERAPY%WIKIPATHWAYS_20260910%WP5609%HOMO SAPIENS	Inhibitors of metabolism in melanoma therapy	PFKFB2	SLC2A1	SLC1A5	LDHA	MAPK3	GLS	PKM	PGLS	PPARGC1A	TRAP1	SLC16A1	SLC16A3	CPT1A	RPS6KA3	RPS6KA2	RPS6KA1	DLAT	G6PD	GPX4	DLD	GSR	MITF	RAF1	ARAF	RPTOR	LDHB	PDHA1	MLST8	PKLR	ACSS1	MTOR	NAMPT	BRAF	MAP2K2;MAP2K1	MAPK1	
SPINAL CORD INJURY%WIKIPATHWAYS_20260910%WP2431%HOMO SAPIENS	Spinal cord injury	PLA2G5	PLA2G6	PLXNA2	RB1	CDKN1B	FOS	GJA1	LGALS3	ROS1	EGR1	CASP3	ROCK2	C1QB	CDC42	CCND1	MYC	VIM	SELP	CD47	AIF1	TNF	TP53	MBP	SOX9	E2F1	RGMA	OMG	CXCL2;CXCL3;CXCL1-1	NTN1	E2F5	GADD45A	NOX4	MAG	IL1B	PPP3CA	CDK4	PLA2G2A-1	GDNF	CDK2	CCNG1	CDK1	BDNF	NR4A1	MMP12	GRIN1	NOS1	IL1R1	LTB4R	CCL13;CCL2	SLIT2	TGFB1	MAPK1	RAC1	CXCL10	MAPK3	RTN4	CHST11	NGFR	APEX1	RHOB	ZFP36	SEMA6A	MIF	ICAM1	PDYN	BCAN	KLK8	LEP	LOC102725035;LOC107987425;LILRB3;LOC112268337;LOC107987441;LOC112268340;LOC112268336;LOC112268334;LOC107987462;LILRB5	BTG2	CCR2	NCAN	RTN4R	TNFSF13B	ANXA1	IL6	TACR1	RHOC	VCAN	LTB	ACAN	MMP9	SLIT1	AQP1	SLIT3	XYLT1	C5	CXCL8	GAP43	NOS2	IL2	GFAP	IL4	IL1A	IFNG	COL4A1	TLR4	EGFR	PRKCA	EPHA4	EFNB2	RHOA	PTGS2-2	PTPRA	FOXO3	COL2A1	PTPRZ1	FKBP1A	CSPG4	AQP4	ARG1	
INTERFERON MEDIATED SIGNALING%WIKIPATHWAYS_20260910%WP4558%HOMO SAPIENS	Interferon mediated signaling	PRKCA	JAK2	IFNE	IFNGR1	IFNK	IFNAR2	JAK1	STAT2	IFNGR2	IFNG	STAT1	IFNB1-4	IL10RB	TYK2	IRF9	IFNAR1	PIK3R1	PIK3CA	IFNLR1	IFNL2;IFNL3;IFNL1	
HEDGEHOG SIGNALING%WIKIPATHWAYS_20260910%WP47%HOMO SAPIENS	Hedgehog signaling	SMO	GRK2	PTCH2	DHH	IHH	GLI2	KIF7	SHH	GLI3	SIN3A	GLI1	ARNTL	PTCH1	STK36	SAP18	
GNAQ PATHWAYS IN PORT WINE STAIN%WIKIPATHWAYS_20260910%WP5437%HOMO SAPIENS	GNAQ pathways in port wine stain	RAF1	MAPK3	MAP2K4	YAP1-1	PDK1	AKT1	MTOR	RHOA	GNAQ	MAP2K5	MAP2K7	MAP2K6	MAP2K3	TRIO	PIK3CA	NFKB1	MAP2K2;MAP2K1	AMOT	MAPK1	RAC1	
VALPROIC ACID PATHWAY%WIKIPATHWAYS_20260910%WP3871%HOMO SAPIENS	Valproic acid pathway	IVD	EHHADH-1	CYP2B6	HDAC1	HADHB-1	CYP2A13;CYP2A6;CYP2A7-1	ABAT	HSD17B10	ACADSB	HADHA	CYP2C9;CYP2C19	ACSM1	
LEPTIN INSULIN SIGNALING OVERLAP%WIKIPATHWAYS_20260910%WP3935%HOMO SAPIENS	Leptin insulin signaling overlap	SOCS2	JAK2	INSR	IRS4	DGKZ	PIK3R3	STAT3	PDPK1	LEP	AKT1	PIK3CG	SOCS1	IRS1	IRS2	LEPR	INS;INS-IGF2	SOCS3	
AMINO ACID METABOLISM PATHWAY EXCERPT HISTIDINE CATABOLISM EXTENSION%WIKIPATHWAYS_20260910%WP4661%HOMO SAPIENS	Amino acid metabolism pathway excerpt histidine catabolism extension	HAL	UROC1	AMDHD1	GPT2	GLUD1;GLUD2	FTCD	
CONGENITAL GENERALIZED LIPODYSTROPHY%WIKIPATHWAYS_20260910%WP5101%HOMO SAPIENS	Congenital generalized lipodystrophy	CAVIN1	AGPAT2	BSCL2	LPIN3	DGAT2	DGAT1	HIF1A	GPAT3	FYN	AKT2	IRS1	CAV1	GRB2	PIK3CA	LPIN1	INS;INS-IGF2	LPIN2	ITGB4	
ANGIOPOIETIN LIKE PROTEIN 8 REGULATORY PATHWAY%WIKIPATHWAYS_20260910%WP3915%HOMO SAPIENS	Angiopoietin like protein 8 regulatory pathway	MAPK9	ANGPTL8	MAPK7	PRKAA1	MAPK6	RXRA	MAPK4	MAP4K5	MAPK14	MAPK12	MAPK13	PDPK1	MAPK10	MAPK11	RHEB	RAPGEF1	CBL	PRKAA2	PRKAG1	CRK	PRKAG2	PRKAG3	PRKAB2	PRKAB1	RPS6KA5	MAP3K8	RICTOR	MAP3K3	GSK3A	MAP3K14	NR1H3	MAPK8	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	RPS6KA3	RPS6KA2	RPS6KA1	SREBF1	MAP3K9	MAP2K7	IRS1	EIF4E	MAP3K4	IRS2	MAP2K6	MAP2K3	FOXO1-1	INS;INS-IGF2	MAP3K1	FASN	ABCG8	ABCG5	MAP3K10	RAF1	MAP3K11	SREBF2	SCD	TSC2	IRS4	AKT2	AKT1	CBLC	MAP3K5	MTOR	RPS6KA4	MAP3K6	GSK3B	PIK3R2	PIK3R1	MAP3K13	MAP2K2;MAP2K1	MAPK1	FLOT1	FLOT2	EIF4EBP1	MINK1	CBLB	MAP3K7	PTPN1	RHOQ	MAPK3	CYP2B6	MAP2K4	MAP3K2	CAP1	MAP3K12	GYS1	RPS6KB1	SOS1	SHC1-1	SHC2	INSR	SESN3	MAPKAP1	EXOC7	TRIP10	SOS2	SLC2A1	RPS6KB2	CYP7A1	PIK3R4	PIK3R3	HRAS	MAP4K3	MAP4K4	MAP4K1	MAP4K2	THRB	THRA	PCK1	SLC2A4	RPTOR	FBP1	RPS6KA6	MLST8	SLC16A2	FOXO3	PIK3CD	PIK3C2G	SHC3	PIK3CB	G6PC1	PIK3C2A	PIK3CG	TSC1	MAP2K5	SLCO1C1	PIK3CA	PIK3C3	LPL	
CILIARY LANDSCAPE%WIKIPATHWAYS_20260910%WP4352%HOMO SAPIENS	Ciliary landscape	MCM2	CD2BP2	BBS9	BBS7	CEP97	ECHS1	CEP290	BBS5	ANKS6	PSMD8	NEK8	BBS2	PSMD7	BBS1	TTC8	VIM	MCM10	CALM1	SNRPB2	RNGTT	LRPPRC	RHBDD2	PSMC6	PSMC4	ZYG11B	HDAC1	PSMD12	POM121;POM121C	STOM	EXOSC4	PSMD13	RAC1	CREBBP	RAB8A	DVL3	AGPAT2	RAB2A	EXOC7	TRAF3IP1	SMC4	COX6C	ARMC8	IFT88	MYL6	INTU	COPS7B	COPS7A	IQGAP1	IQGAP2	CDR2	AAR2	CTSA	EXOC6B	BBIP1	AIMP1	EHD3	WNK1	RANBP10	GDI1	APC	MYL6B	TNKS1BP1	TMED1	CNOT6L	EIPR1	RAB3IL1	NME8	EXOC4	EXOC3	EXOC5	MAPRE2	EXOC1	YAP1-1	WDR26	EXOSC7	PGRMC2	EXOSC9	EXOSC2	WHRN	UBE2D3;UBE2D2	TIPRL-2	MKLN1	GID4	GID8	YPEL5	DGKE	MAEA	APMAP	LZTFL1	TTC30A;TTC30B	LCN2	ERF	ARL8B	SPATA7	CDH23	UBE2H	TFAP2D	FUZ	CNOT10	LSM4	IFT20	COPS4	COPS3	COPS5	CNOT1	COPS2	COPS8	TFAP2E;TFAP2B	TTC26	ZMYND19	MCM8	RAB14	MCM9	RPGR	IFT52	IFT57	IQCB1	RBM14	ARFGAP3	RABEP2	SSNA1	EFHC2	CCDC40	VPS4A	USH1C	EHBP1	RAB21	RMND5B	DNPEP	RMND5A	DCAF11	LCA5	MFAP1	VAPB	CLUAP1	CTNNB1	TFAP2A	RB1	TFAP2C	UQCC1	CNOT9	MKS1	DOCK5	SNAP29	ARHGDIA	NEK7	RALB	CTBP2	MSH2	IQGAP3	H3-3A	HDAC2	GLB1	ACSL3	NEFL	DDX5	PAFAH1B1	COPS6	NFKB1	BBS4	NDUFA9	NUP133	NDUFA5	NEFM	CBS;CBSL	MCM7	MCM3	NUP88	MCM4	MCM5	MCM6	IFT172	DCAF7	IFT74	AFG3L2	WEE1	HTRA2	GLA	CAMK2A	XPNPEP3	EXOC8	EXOC2	DYNC2I2	DYNC1H1	EIF5B	DYNC1I2	DYNC2I1	DYNLT1	NUDC	IFT140	DYNLT2B	IFT122	IFT80	HSPB11	DYNC1LI1	IFT22	IFT43	IFT81	RANBP9	IFT27	DYNLRB2	DYNLRB1	IFT46	EXOC6	EFTUD2	TBC1D4	
ANGIOGENESIS OVERVIEW%WIKIPATHWAYS_20260910%WP1993%HOMO SAPIENS	Angiogenesis overview	NRP1	MAP3K7	ROBO4	MAP2K4	SHB	ROBO1	TIMP4	BAD	WAS	MAPK14	ATF2	BMX	ELK1	PDPK1	PTPN11	MAPK11	PLXND1	DOK2	SEMA4A	MMP2	F2	GRB2	DAG1	MMP9	SOS1	CRK	SHC1-1	VHL	SRC	CDC42	PAK1	KDR	FGF1	PTK2B	IQGAP1	VEGFA	NOX4	APC	PRKCA	GRB14-1	GRB7	SEMA3A	MAPK8	PLCG1	PLA2G1B	KRAS	MAP2K6	NCK1	RAF1	MMP14	NOS3	FGFR1	TIMP2	PIK3CD	AKT1	PXN	MTOR	ANGPT1	FRS2	TEK	SLIT2	MAP2K2;MAP2K1	MAPK1	RAC1	
4P16 3 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5365%HOMO SAPIENS	4p16 3 copy number variation	H3-3A	MAPK3	PLCG1	SLBP	GAB1	NSD2	CLTCL1	TMEM129	FAM53A	POLN	CKAP5	LETM1	TACC3	C4orf48	CBL	BCS1L	GRB2	SOS1	FGFR3	ERI1	FGF2	FRS2	UBE2J2	NELFB	NELFA	NELFCD	NELFE	PIK3R1	NAT8L	MAPK1	
EBSTEIN BARR VIRUS LMP1 SIGNALING%WIKIPATHWAYS_20260910%WP262%HOMO SAPIENS	Ebstein Barr virus LMP1 signaling	TRAF6	MAP3K7	PDLIM7	MAPK8	CCL5	TRADD	TNF	HSP90AA1	IFNB1-4	CCL20	IKBKB	CHUK	IKBKG	IRAK1	TRAF1	RELA	MAP3K3	NFKBIA	NFKB1	NFKB2	MAPK1	CXCL8	MAP3K14	
ENDOPLASMIC RETICULUM STRESS RESPONSE IN CORONAVIRUS INFECTION%WIKIPATHWAYS_20260910%WP4861%HOMO SAPIENS	Endoplasmic reticulum stress response in coronavirus infection	PPP1R7	PPP1CA	PPP1R12A	MAPK8	EIF2S1	PPP1CB	PPP1CC	PPP1R14A	PPP1R15B	PPP1R13B	PPP1R11	PPP1R10	PPP1R8;STX12	PPP1R2-1	PPP1R9A	DDIT3	PPP1R16B	BCL2	PPP1R14B	PPP1R16A	PPP1R3G	PPP1R3F	PPP1R1A	PPP1R3C	PPP1R3B	PPP1R3E	PPP1R1C	PPP1R12C	PPP1R1B	PPP1R3D	PPP1R12B	PPP1R14D	ATF6	ATF4	MAP1LC3A	MBTPS1	ERN1	PPP1R15A	XBP1	EIF2AK1	EIF2AK3	EIF2AK2	HSPA5	PPP1R3A	MBTPS2	PPP1R14C	
FATTY ACID AND LIPOPROTEIN TRANSPORT IN HEPATOCYTES%WIKIPATHWAYS_20260910%WP5323%HOMO SAPIENS	Fatty acid and lipoprotein transport in hepatocytes	APOA4	SORT1	ACSL6	ACSL5	APOC2	SCARB1	PCSK9	LDLRAP1	MYLIP	ACSL3	SLC27A1	APOE	APOB	LDLR	ABCA1	FABP2	SOAT1	STAR	FABP1	FABP3	FABP4	ACSL1	SLC27A4	LIPA	STARD3	VDAC1	OSBPL5	NPC2	SOAT2	APOC1	SLC27A3	LRP1	SLC27A2	
TYPE I INTERFERON INDUCTION AND SIGNALING DURING SARS COV 2 INFECTION%WIKIPATHWAYS_20260910%WP4868%HOMO SAPIENS	Type I interferon induction and signaling during SARS CoV 2 infection	MYD88	TRAF6	IRF3	JAK1	STAT1	MAVS	TYK2	TRAF3	TMPRSS2	IFNAR2	STAT2	OAS3	TLR9	TLR6	TLR2	TLR7	TLR4	TLR3	OAS1	TREML4	IRF9	ACE2	IFNAR1	IFIH1	EIF2AK2	TBK1	IRF7	IRAK4	IKBKE	DDX58	
SRF AND MIRS IN SMOOTH MUSCLE DIFFERENTIATION AND PROLIFERATION%WIKIPATHWAYS_20260910%WP1991%HOMO SAPIENS	SRF and miRs in smooth muscle differentiation and proliferation	MYOCD	MEF2A	MEF2B;BORCS8-MEF2B	KLF4	MEF2D	CAMK2D	NKX2-5	MEF2C	CCND2	ELK1	SRF	
ALPHA 6 BETA 4 SIGNALING%WIKIPATHWAYS_20260910%WP244%HOMO SAPIENS	Alpha 6 beta 4 signaling	PRKCA	EIF4EBP1	MAPK3	LAMC2	LAMC1	PRKCD	MAPK14	HRAS	GAB1	PTPN11	RHOA	IRS1	IRS2	ITGA6	GRB2	LAMA5	LAMA2	SOS1	LAMA1	SHC1-1	LAMA3	SRC	LAMB3	LAMB2	LAMB1	AKT1	MTOR	PIK3R2	PIK3R1	PTK2	MAPK1	ITGB4	RAC1	
FATTY ACID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP357%HOMO SAPIENS	Fatty acid biosynthesis	PC	HADH	ACSL6	ACSL5	ACLY	ECHS1	ACSL1	SCD	ACAA2	ECH1	ECHDC1	ECHDC2	ECHDC3	DECR1	PECR	ACSS2	ACACA	ACSL3	MECR	ACSL4	ACACB	FASN	
10Q22Q23 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5402%HOMO SAPIENS	10q22q23 copy number variation	NRG3	ERBB4	IQUB	SMC3	CEBPA	MAT1A	NME5	MAS1	TNFSF11	RSPH9	SMC1A	RAD21	RSPH3	AFG3L2	STAG1	SH2D4B	ADIRF	VEGFA	BUB1B	LDB3	GHITM	SF3B4	FAM25A;FAM25C;FAM25G;FAM25E-1	GRID1	MAD2L2	CDHR1	ADAM10	MMRN2	SH3GL3	DYDC2	RGR	BMP2	PDS5B	PDS5A	SNCG	C10orf99	RSPH4A	SUSD2	WAPL	TSPAN14	RSPH1	LRIT2	SHLD3	LRIT1	PRXL2A	SHLD2	SHLD1	GPR15	CCSER2	ZMYND11	GLUD1;GLUD2	ACTN2	BMPR1A	ROPN1L	OPN4	RSPH6A	SIRT4	DNAJB13	PPARG	NFKB1	DYDC1	
SYNTHESIS OF CERAMIDES AND 1 DEOXYCERAMIDES%WIKIPATHWAYS_20260910%WP5194%HOMO SAPIENS	Synthesis of ceramides and 1 deoxyceramides	DES	B4GALT1	SGMS1	B3GNT5	DGAT1	SPTLC1	ASAH1	SGMS2	CERS3	UGT8	CERS5	UGCG	KDSR	CERS6	CERS4	CERK	CERS1	B4GALNT1	SPHK1	A4GALT	CERS2	A3GALT2	
AKT SIGNALING AND ARTD FAMILY MEMBERS%WIKIPATHWAYS_20260910%WP5531%HOMO SAPIENS	AKT signaling and ARTD family members	PIK3R4	PIK3R3	PARP1	PIK3R6	ATM	PIK3R5	SIRT1	IKBKG	PARP3	PHLPP1	FOXO1-1	PARP2	RPTOR	STK11	TSC2	MAPKAP1	MLST8	PDK1	PIK3CD	AKT2	PIK3C2G	AKT3	PIK3CB	AKT1	PIK3C2A	MTOR	PIK3CG	TSC1	PIK3C2B	GSK3B	PIK3R2	RICTOR	PIK3R1	PIK3CA	
OSTEOCLAST SIGNALING%WIKIPATHWAYS_20260910%WP12%HOMO SAPIENS	Osteoclast signaling	ATP6V1G1	ITGB3	TNFRSF11A	SPP1	GPR68	MAPK8	PDGFB	IFNB1-4	IFNAR1	TRPV5	SLC9A1	TNFSF11	ACP5	TNFRSF11B	AIMP2	CTSK	
SEROTONIN TRANSPORTER ACTIVITY%WIKIPATHWAYS_20260910%WP1455%HOMO SAPIENS	Serotonin transporter activity	ITGB3	STX1A	IL1B	SLC6A4	MAOA	NOS1	IL1R1	TPH2	SCAMP2	TGFB1I1	PPP2CB;PPP2CA	
NEURAL CREST DIFFERENTIATION%WIKIPATHWAYS_20260910%WP2064%HOMO SAPIENS	Neural crest differentiation	DLL1	DLL3	DLL4	TFAP2A	CTNNB1	MYC	ASCL1	FGF2	MBP	SOX9	PAX3	AXIN2	SOX5	HOXA1	CTBP2	OLIG1	OLIG2	SOX10	HDAC6	BMP4	TCF4	HDAC2	LHX1	HDAC11	MSX2	MIA	HOXB1	PHOX2B	GJB1	LHX2	LHX5	CDH1	DMBX1	ZIC1	FOXD3	OLIG3	FZD3	DCT	WNT3A	PRTG	GBX2	GSK3B	HDAC1	NFKB1	NFKB2	CDH7	HDAC3	TLX2	PAX7	RHOB	HAND1	CDH6	CDH2	DLX5	SNAI1	SNAI2	NEUROG1	COL11A2	MITF	DVL1	MSX1	DVL2	DVL3	GFAP	FGF19	BMP7	HDAC4	HDAC5	RBPJ	MYB	AXIN1	HDAC8	HDAC9	HDAC7	FGF8	HES1	HES5	ISL1	TCF7L1	NOTCH2	NOTCH3	NOTCH1	NOTCH4	WNT1	SMAD1	ID1	TBX6	ETS1	FGFR3	FGFR2	FGFR1	TFAP2E;TFAP2B	COL2A1	HDAC10	HEY2	MPZ	ITGB1	WNT8A	PMP22	
FERROPTOSIS%WIKIPATHWAYS_20260910%WP4313%HOMO SAPIENS	Ferroptosis	NCOA4	ACSL6	ACSL5	TXNRD1	CBS;CBSL	SAT1	PCBP2	SLC7A11	STEAP3	CP	SLC39A14	HMOX1	VDAC3	CTH	TP53	TFRC	SLC3A2	SLC40A1	COQ2	MAP1LC3B2;MAP1LC3B-1	SLC38A1	ACSL4	NOX4	ATG7	ATG5	NOX1	ALOX15	GCH1	SLC1A5	MAP1LC3C	FTL-1	BACH1	SLC11A2	TF	FDFT1	GPX4	GSS	ACSL3	GCLC	GCLM	ACSL1	POR	CISD1	SAT2	AIFM2	VDAC2-1	CHMP6	CHMP5	IREB2	DPP4	FTMT	PCBP1	MAP1LC3A	CYBB	HMGCR	PHKG2	PRNP	HSPB1	LPCAT3	FTH1	SLC39A8	
NOTCH SIGNALING%WIKIPATHWAYS_20260910%WP268%HOMO SAPIENS	Notch signaling	DLL1	PSEN1	DLL3	DLL4	HDAC2	NOTCH2	NOTCH3	NOTCH1	CREBBP	NCOR2	NOTCH4	KAT2A	NUMB	NUMBL	JAG2	JAG1	PTCRA	DTX3L	DVL1	DVL2	DVL3	KAT2B	MAML1	APH1A	RBPJ	NCSTN	DTX1	APH1B	RBPJL	ADAM17	DTX2	RFNG	HDAC1	DTX3	HES1	LFNG	INPP5K	HES5	KCNJ5	CTBP2	CTBP1	PSEN2	MFNG	MAML3	DTX4	
TARGETING YAP IN PANCREATIC DUCTAL ADENOCARCINOMA PDAC %WIKIPATHWAYS_20260910%WP5495%HOMO SAPIENS	Targeting YAP in pancreatic ductal adenocarcinoma PDAC	CCN1	PRKAA1	RHOB	STK3	SAV1	YAP1-1	TEAD1	CCN2	TEAD3	MOB1A;MOB1B	TEAD4	LATS2	RHOA	LATS1	RHOC	PRKAA2	TEAD2	PRKAG1	PRKAG2	PRKAG3	RHO	PRKAB2	PRKAB1	HMGCR	STK4	RHOD	
10Q11 21Q11 23 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5352%HOMO SAPIENS	10q11 21q11 23 copy number variation syndrome	OGDHL	EIF4ENIF1	FAM170B	VSTM4	MEN1	C10orf71	BAZ1B	RGMB	WDFY4	SMARCC2	PARG	LRRC18	MYO1C	ERCC8	ARHGAP22	ERCC6	ATF2	HSF1	ELK1	HSF4	DRGX	DDX21	KDM4D	C10orf53	SMARCA5	DEK	SMARCB1	TMEM273	UVSSA	CLOCK	DLD	GDF5	JUND	DLST	ITCH	SLC18A3	NLRP3	ARNTL	BMP2	NEO1	MAPK8	MYBBP1A	SF3B1	SIRT1	SMAD1	CUL5	ELOA	BCL2	SMAD9	CDH1	ERCC5;BIVM-ERCC5	SMAD5	BMPR1B	BMPR1A	NOG	SIRT6	PCNA	CHAT	RIF1	FRMPD2	
PENTOSE PHOSPHATE METABOLISM%WIKIPATHWAYS_20260910%WP134%HOMO SAPIENS	Pentose phosphate metabolism	RPIA	TALDO1	RPE;RPEL1	G6PD	TKT	PGLS	PGD	
T CELL ACTIVATION SARS COV 2%WIKIPATHWAYS_20260910%WP5098%HOMO SAPIENS	T cell activation SARS CoV 2	JAK2	MAPK3	CD3G	IL12B	CD3E	IKBKB	PDPK1	TYK2	IKBKG	CHUK	CD247	CDKN1A	FOS	RHEB	CD3D	IRF2BPL	PTPRC	GRAP2	RELA	GRB2	CCL28	IL18R1	SOS1	BCL2L1	NFKBIA	CARD11	BCL10	MALT1	CCND1	IL2	IL4	IFNG	LCP2	IL12A	LAT	PTEN	TNF	IFNB1-4	TP53	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	CD4	HLA-DRA	RICTOR	CCL19	CD28	IL17A	MYD88	DEPTOR	PRKCQ	RASGRP1	PPP3CC	PLCG1	BAX	HRAS	ICOS	LTA	IL23R	JUN	STAT4	RAF1	LCK	IL12RB1	RPTOR	IL12RB2	IFNAR2	NFATC1	IL23A	TSC2	MLST8	FYN	FOXO3	PIK3CD	CD86	AKT1	MTOR	CD80	TSC1	IFNAR1	CTLA4	GSK3B	CDKN2A	PIK3R1	ZAP70	ITPR1	MAP2K2;MAP2K1	NFKB1	MAPK1	
NRXN1 DELETION SYNDROME%WIKIPATHWAYS_20260910%WP5398%HOMO SAPIENS	NRXN1 deletion syndrome	NLGN1	NLGN3	GRIN1	GRIA1	GRIA3	GRIA4	NLGN2	GRIA2	GRIN3B	NLGN4X;NLGN4Y	GRIN2A	GRIN3A	NRXN1;NRXN3;NRXN2	GRIN2C	GRIN2B	DLG4	GRIN2D	
PHOSPHOINOSITIDE 3 KINASE PI3K FAMILY%WIKIPATHWAYS_20260910%WP5472%HOMO SAPIENS	Phosphoinositide 3 kinase PI3K family	PIK3R4	PIK3R3	PIK3CD	PIK3R6	PIK3C2G	PIK3R5	PIK3CB	PIK3C2A	PIK3CG	PIK3C2B	PIK3R2	PIK3R1	PIK3CA	
TARGET OF RAPAMYCIN SIGNALING%WIKIPATHWAYS_20260910%WP1471%HOMO SAPIENS	Target of rapamycin signaling	PRKCA	EIF4EBP1	PRKAA1	IDI1	RHEB	RPS6KB1	RRAGC	PRKAA2	PRR5	PRKAG1	PRR5L	PRKAG2	DDIT4L	RRAGA	PRKAG3	RRAGB	RRAGD	ULK3	CDC42	PRKAB2	RPTOR	PRKAB1	TSC2	MAPKAP1	MLST8	ULK2	ULK1	AKT1	MTOR	HMGCR	TSC1	FKBP1A	RICTOR	AKT1S1	DDIT4	RAC1	
DNA IR DOUBLE STRAND BREAKS AND CELLULAR RESPONSE VIA ATM%WIKIPATHWAYS_20260910%WP3959%HOMO SAPIENS	DNA IR double strand breaks and cellular response via ATM	TRAF6	UPF1	ACTL6A	ATF2	HSF1	SMC3	MRE11	BRCA1	CASP9	CHEK2	CASP3	CHEK1	MCPH1	NBN	APAF1	SMC1A	CDC25C	FANCD2	BRCA2	DCLRE1C	TP53	MDM2-2	BLM	ABL1	E2F1	BAK1	BID	RAD52	RAD50	RAD51	CDK5	RNF8	PRKDC	STK3	RAD17	YAP1-1	BAX	PARP1	ATM	ATR	MDC1	RAD9A	TP53BP1	LATS1	EXO1	TERF2	TRIM28	TP73	PCNA	CDKN2A	RASSF1	NABP2	RIF1	KAT5	
T CELL ANTIGEN RECEPTOR TCR PATHWAY DURING STAPHYLOCOCCUS AUREUS INFECTION%WIKIPATHWAYS_20260910%WP3863%HOMO SAPIENS	T cell antigen receptor TCR pathway during Staphylococcus aureus infection	MAP3K7	MAPK9	MAPK3	PDCD1	CSF2	IKBKB	IKBKG	CHUK	ITK	FOS	CD3D	RRAS	CBL	PTPRC	GRAP2	GRB2	DAG1	SOS1	NFKBIA	IL10	CARD11	BCL10	PTPN6	MALT1	CHP1	PAK1	AHSA1	IL2	IL4	IFNG	CD40LG	LCP2	LAT	TNF	IL5	CD4	MAP3K8	CD28	CALM1	MAP3K14	PRKCQ	CDK4	PLCG1	ICOS	NFATC2	MAP2K7	DLG1	JUN	NCK1	RAF1	LCK	CD8A	PDK1	FYN	AKT1	CTLA4	GSK3B	PIK3CA	ZAP70	MAP2K2;MAP2K1	NFKB1	
APOPTOSIS MODULATION AND SIGNALING%WIKIPATHWAYS_20260910%WP1772%HOMO SAPIENS	Apoptosis modulation and signaling	TRAF6	MAPK3	BAD	CASP5;CASP4	IKBKB	BCL2A1	FOS	BBC3	CASP9	PIDD1	BCL2L1	AIFM1	NFKBIA	CASP3	HRK	APAF1	PEA15	BOK	BIRC7	SEPTIN4-1	BIRC2	PTRH2	BIRC3	MADD	ENDOG	TNFRSF25	BLK	DIABLO-1	BCL2L10	CFLAR	BAG3	BMF	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	BNIP3	TP53	HTRA2	BCL2L2	CYCS-1	IL1R2	IRAK1	CASP7	CASP1	PMAIP1	CASP6	CASP2	BAK1	BID	MCL1	TOLLIP	MAP3K14	MYD88	PRKD1	PTPN13	MAPK8	CASP8	FAS	BAX	TRADD	XIAP	RIPK1	FADD	CRADD	TNFRSF1A	JUN	TRAF3	BCL2	DFFB	DFFA	CAPNS1	TNFRSF1B	BIRC5	IL1R1	AIFM2	BCL2L11	MAP3K5	HSPA1A;HSPA1B	FASLG	DAXX	NAIP	BIK	CDKN2A	CASP10	TNFSF10	NFKB1	SMIM40	
NON SMALL CELL LUNG CANCER%WIKIPATHWAYS_20260910%WP4255%HOMO SAPIENS	Non small cell lung cancer	MAPK3	RXRA	PLCG2	BAD	STAT3	PDPK1	RET	JAK3	RB1	CDKN1A	HGF	GRB2	CASP9	SOS1	STAT5A	STAT5B	EGF	CASP3	EML4	CCND1	TGFA	ERBB2	RASSF5	DDB2	POLK	TP53	FHIT	CYCS-1	SOS2	EGFR	E2F1	E2F2	E2F3	PRKCG	BAK1	BID	GADD45B	GADD45A	PRKCB	GADD45G	PRKCA	CDK6	CDK4	NRAS	PLCG1	CASP8	BAX	HRAS	KRAS	ALK	RXRB	RAF1	MET	RXRG	ARAF	CRABP2	CRABP1	KIF5C	FOXO3	PIK3CD	KIF5B	AKT2	KIF5A	AKT3	PIK3CB	AKT1	RARB	CDKN2A	BRAF	PIK3CA	RASSF1	STK4	MAP2K2;MAP2K1	MAPK1	
16P12 2 COPY NUMBER VARIATION SYNDROME 520KB %WIKIPATHWAYS_20260910%WP5510%HOMO SAPIENS	16p12 2 copy number variation syndrome 520kb	NDUFA9	MAPK3	POLR3E	PRKAA1	NDUFA4	MAPK14	MAPK12	MAPK13	CDH18	MAPK11	UQCRB	UQCR11	UQCR10	RPS6KB1	PRKAA2	UQCRQ	PRKAG1	UQCRC1	PRKAG2	UQCRFS1	CYC1	PRKAG3	UQCRC2	PRKAB2	COX7C	PRKAB1	COX5A	RAB5IF	TRPM7	PDZD9	SDR42E2	VWA3A	CDR2	MOSMO-1	CALM1	CALM2	CDK2	CDK1	TRAP1	RPS6KA1	EEF2K	EEF2	CALM3;CALM1	RPTOR	NDUFS8	NDUFS3	MLST8	MTOR	MAP2K2;MAP2K1	MAPK1	NDUFV1	
HOMOLOGOUS RECOMBINATION%WIKIPATHWAYS_20260910%WP186%HOMO SAPIENS	Homologous recombination	RAD52	RAD50	NBN	RAD51	RAD54B	POLD3	POLD4	BRCA2	ATM	POLD1	POLD2	MRE11	RPA1	
PHOTODYNAMIC THERAPY INDUCED NF KB SURVIVAL SIGNALING%WIKIPATHWAYS_20260910%WP3617%HOMO SAPIENS	Photodynamic therapy induced NF kB survival signaling	TRAF6	IL1B	CSF2	ICAM1	BCL2A1	IKBKB	MMP1	CHUK	TNFRSF1A	IL6	MMP2	RELA	PTGS2-2	MMP9	MMP3	CXCL8	CCND1	IL2	VCAM1	SELE	IL1A	BIRC5	BIRC2	BIRC3	CD40LG	CFLAR	TNF	BCL2L2	REL	RELB	VEGFA	CXCL2;CXCL3;CXCL1-1	NFKB1	NFKB2	EGLN2	
SARS COV 2 INNATE IMMUNITY EVASION AND CELL SPECIFIC IMMUNE RESPONSE%WIKIPATHWAYS_20260910%WP5039%HOMO SAPIENS	SARS CoV 2 innate immunity evasion and cell specific immune response	CXCL10	IL6R	TRAF6	IRF3	JAK1	CSF2	STAT1	MAVS	NUP98	EP300	TFAP2A	IL6	TRAF2	CCL3L1;CCL3L3;CCL3;CCL18	IL10	CXCL8	RAE1	CCL4L2;CCL4L1;CCL4	TP53I3	PF4;PF4V1-1	LARP1-1	TLR7	TNF	CXCL13	IFNB1-4	CXCL9	TANK	CXCL17	IFIT2	AP1G1	IRF7	BSG	CXCL2;CXCL3;CXCL1-1	LAG3	CD160	PPBP	CXCL11	HDAC2	CASP8	HAVCR2	TRADD	RIPK1	FADD	TRAF5	CXCL12	TRAF3	IFITM3;IFITM2;IFITM1	SMAD2;SMAD3	IFNAR2	STAT2	CCL5	MX1-1	ACE2	CCL13;CCL2	IFNAR1	TBK1	CXCR2	DHX58	TGFB1	TRIM25	CXCL5;CXCL6	NFKB1	DDX58	
MINERALOCORTICOID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP5279%HOMO SAPIENS	Mineralocorticoid biosynthesis	SRD5A2	AKR1D1	HSD11B1	HSD11B2	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	CYP21A2	CYP11B1;CYP11B2	SRD5A1	
MOLECULAR PATHWAY FOR OXIDATIVE STRESS%WIKIPATHWAYS_20260910%WP5477%HOMO SAPIENS	Molecular pathway for oxidative stress	MAP2K4	MAPK14	ATF2	ICAM1	IKBKB	KEAP1	IKBKG	CDKN1A	FOS	IL6	RHEB	BCL2L1	CXCL8	CHEK1	NOS2	SOD2	IL1A	HMOX1	CREB1	RPS6KA5	PTEN	TNF	CCNE1	TP53	NFE2L2	MDM2-2	CAT	IPCEF1	PIP-1	NOX1	GSX1	CDK2	MAPK8	PINK1	ATR	SIRT1	CUL3	PTGS2-2	MAP2K3	FOXO1-1	BCL2	NQO1	NRF1	AKT1	MAP3K5	MTOR	TSC1	PIK3CA	NFKB1	
SODIUM CHANNEL IN EPILEPSY%WIKIPATHWAYS_20260910%WP5598%HOMO SAPIENS	Sodium channel in epilepsy	JAK2	PTPRN	PSEN1	RACK1	SCNM1;TNFAIP8L2-SCNM1	SCN11A	PDCD10	FGF13	SCN7A	FGF12	SCN3B	SCN3A	SCN1B	CAMK2A	MAPK8IP2	BACE1	NFASC	SCN4A	SCN4B	SCN2B	RNF121	NEDD4	PRRT2	SCN9A	SCN1A	SCN10A	SCN2A	SCN8A	FYN	TNF	WEE1	AKT1	GSK3B	NEDD4L	SCN5A	FGF14	CALM1	
FGFR3 SIGNALING IN CHONDROCYTE PROLIFERATION AND TERMINAL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP4767%HOMO SAPIENS	FGFR3 signaling in chondrocyte proliferation and terminal differentiation	BMP4	BMP2	MAPK3	STAT1	MAPK14	MAPK12	MAPK13	NPR2	MAPK11	PTH1R	CDKN1A	SNAI1	THRA	PPP2CB;PPP2CA	RAF1	FGF18	FGFR3	CNP	IHH	SOX9	RBL1	FGF9	MAP2K2;MAP2K1	MAPK1	PTHLH	ATG5	
DISORDERS OF NAD METABOLISM%WIKIPATHWAYS_20260910%WP5506%HOMO SAPIENS	Disorders of NAD metabolism	NADSYN1	BST1	NAXE	NAXD	CD38	
WNT BETA CATENIN SIGNALING INHIBITORS IN CURRENT AND PAST CLINICAL TRIALS%WIKIPATHWAYS_20260910%WP5442%HOMO SAPIENS	Wnt Beta catenin signaling inhibitors in current and past clinical trials	CTNNB1	CREBBP	PORCN	LRP6	LRP5	
MAMMARY GLAND DEVELOPMENT INVOLUTION STAGE 4 OF 4%WIKIPATHWAYS_20260910%WP2815%HOMO SAPIENS	Mammary gland development involution stage 4 of 4	CDH1	MYC	E2F1	IL6ST	MMP9	BAX	SOCS3	STAT3	CHI3L1	TP53	
ETHANOL EFFECTS ON HISTONE MODIFICATIONS%WIKIPATHWAYS_20260910%WP3996%HOMO SAPIENS	Ethanol effects on histone modifications	HDAC3	HDAC2	AHCY	TYMS	MTR-1	ATF2	SLC19A1	DHFR2;DHFR	ADH1C;ADH1B;ADH1A	ELP3	ALDH2	ALDH1A1	MAT1A	ACSS2	MTHFR	KAT2B	HDAC4	HDAC5	ALDH1A3	HDAC8	HDAC9	HDAC10	HDAC7	HDAC1	ALDH1A2	CYP2E1	EHMT2	HAT1	HDAC6	
NF1 COPY NUMBER VARIATION SYNDROME %WIKIPATHWAYS_20260910%WP5366%HOMO SAPIENS	NF1 copy number variation syndrome	H4C6	ARF6	MAPK3	JARID2	NGFR	MAP3K2	MAVS	TUBB4A;TUBB;TUBB8B;TUBB8	RTN4R	SOS1	EGF	EIF3A	ROCK2	CFL1	EXOC7	CCNE2	PRMT5	CCNE1	IFNB1-4	CCNA2-1	EGFR	OMG	MCL1	HOXA1	SUPT5H	MYT1	DNMT1	RAD51	EXOC4	PER1	EXOC3	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	EXOC5	EXOC1	ATR	NF1	RAD9A	EXOC8	WDR48	RHOA	NGF	HOXA9	EXOC2	POLRMT	EVL	ATAD5-1	SDC2	RNF135	INPP5A	MAP3K1	RFC5	RBBP7	RFC3	E2F6	RFC4	RAB11FIP4	BCL2	RFC2	TEFM	SUZ12	RAF1	UTP6	COPRS	EVI2A	CRLF3	EVI2B	METAP2	LIMK1	EED	SYN1	EZH1	EXOC6	USP1	PCNA	H4-16	ADAP2	RAB11A	CRY1	MAPK1	H4C1	DDX58	
SPHINGOLIPID PATHWAY%WIKIPATHWAYS_20260910%WP1422%HOMO SAPIENS	Sphingolipid pathway	PPP1CA	SGMS1	ASAH1	CERS3	CERS5	CERS6	CERK	GAL3ST1	SPHK2	SPHK1	PPP2CB;PPP2CA	ASAH2	SGPL1	SPTLC3	CERT1	SGPP2	ACER1	SERINC1	PLPP1	SPTLC1	GBA	SGMS2	GBA2	UGT8	UGCG	KDSR	CERS4	CERS2	B4GALT6	
PDGFR BETA PATHWAY%WIKIPATHWAYS_20260910%WP3972%HOMO SAPIENS	PDGFR beta pathway	JAK2	PRKCA	RASA1	MAPK3	JAK1	MAP2K4	MAPK8	PLCG1	STAT1	HRAS	STAT3	ELK1	FOS	GRB2	JUN	MAP3K1	SOS1	STAT5A	STAT5B	SHC1-1	RAF1	PDGFRB	STAT6	EIF2AK2	PIK3R1	PIK3CA	MAP2K2;MAP2K1	PRKCB	SRF	
STEROIDOGENIC PATHWAY%WIKIPATHWAYS_20260910%WP4463%HOMO SAPIENS	Steroidogenic pathway	HSD17B1	STAR	CYP19A1	CYP17A1	HSD3B1;HSD3B2	CYP11A1	
13Q12 12 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5406%HOMO SAPIENS	13q12 12 copy number variation	DMD	LINGO1	MAG	MAPK9	FLNC	RTN4	MAPK8	RHOA	RTN4R	SGCD	TRAF5	SGCA	MIPEP	SGCB	ADIPOQ	TRAF1	DAG1	TRAF2	SGCG	TRAF3	CDC42	SACS	DTNA	SSPN	SNTB1	C1QTNF9B;C1QTNF9	ATXN1	SNTA1	TNFRSF19	SPATA13	RAC1	
11P11 2 COPY NUMBER VARIATION SYNDROME %WIKIPATHWAYS_20260910%WP5348%HOMO SAPIENS	11p11 2 copy number variation syndrome	MS4A1	ITGB2	CD63	IGSF8	PHF21A	CD19	ALX4	TP53I11	PEX16	SYT13	HBEGF	SDCBP	REST	B4GAT1	TSPAN18	IZUMO1-1	ITGA4	ITGA3	CLOCK	ITGA6	LGALS3BP	TIMP1	CHST6	EXT1	EXT2	SHH	TP53	CD4	LEF1	HLA-DRA	HLA-DMB	ARNTL	CHST1	B4GALT4	VANGL1	NRXN1;NRXN3;NRXN2	HLA-DMA	CD151	NDST1	GLI3	CD82	SPPL2C	ACCS	C11orf96	C11orf94	LARGE2	ALKBH3	CD53	SLC35C1	MAPK8IP1	ITGB1	SLC25A17	B3GNT7	CRY2	PEX3	PRDM11-1	
NICOTINE EFFECT ON DOPAMINERGIC NEURONS%WIKIPATHWAYS_20260910%WP1602%HOMO SAPIENS	Nicotine effect on dopaminergic neurons	GNB1	GNG2	CDK5	GNAI1	PPP1CA	PRKACA-1	PPP1R1B	DRD2	DRD3	DRD4	CHRNA3	KCNK9	CHRNA5	TH	CHRNA4	CHRNA6	KCNK3	SLC18A2	CHRNB2	DDC	ADCY2	
T CELL RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP69%HOMO SAPIENS	T cell receptor signaling	TRAF6	SKAP1	CBLB	MAP3K7	MAPK9	MAPK3	PRKCD	WAS	MAPK14	ATF2	CD3G	VAV3	CD3E	IKBKB	PDPK1	PTPN11	IKBKG	CHUK	VAV1	CD247	ITK	GAB2	PSTPIP1	FOS	DBNL	CD3D	FYB1	CBL	GRAP2	RELA	GRB2	SOS1	CRK	NFKBIA	SHC1-1	CARD11	BCL10	MALT1	CDC42	PAK1	CREB1	LCP2	LAT	CD4	PTK2B	MAP3K8	CD28	MAP3K14	PRKCQ	MAPK8	PLCG1	HRAS	ICOS	NFATC2	MAP4K1	JUN	NCK1	CRKL	RAF1	LCK	CD8A	NFATC1	RIPK2	FYN	AKT1	REL	PIK3R2	PIK3R1	ZAP70	ITPR1	SH2B3	MAP2K2;MAP2K1	NFKB1	MAPK1	
CYTOKINE CYTOKINE RECEPTOR INTERACTION%WIKIPATHWAYS_20260910%WP5473%HOMO SAPIENS	Cytokine cytokine receptor interaction	TPO	INHBB	CCL27	CCL26	CNTFR	IL27RA	IL36A	IL36B	TNFSF14	XCL1;XCL2	GDF2	IL36G	GDF1	GDF6	GDF7	EPO	IL1F10	IL22RA1	CD27	IL20	TNFRSF13B	PF4;PF4V1-1	IL26	IL27	CNTF	TNFRSF13C	CD40LG	BMP15-1	IL17RB	CCL14	CXCR6	RELT	TNF	CCL8	GDF10	CXCL13	CCL25	GDF11	CCL24	IL31	IL1RAP	IL37	CD70	IL34	CXCR5	BMP8B	ACKR4	CLCF1	NFIC	LIF	CCL19	AMHR2	CXCL2;CXCL3;CXCL1-1	MPL	TNFRSF8	CCL21	IL13RA2	EDAR	CXCL11	TNFRSF17	IL36RN	TNFRSF14	BMP4	INHBC	INHBE	TNFRSF18	IL9R	IL17RC	IL1RL2	ACVR1C	LTBR	TNFRSF4	IL11RA	TNFRSF1A	CCL22	TNFRSF9	TNFSF9	TGFBR1-1	IL13RA1	TNFRSF1B	ANP32B	TSLP	MSTN	TNFRSF12A	ACVR2A	IL10RA	IL6R	NGFR	TNFSF13B	IL6	TNFSF11	LTB	IL6ST	IFNLR1	IFNL2;IFNL3;IFNL1	IL10	CCL11	CXCL8	IL18	CSF3R	IL2	IL4	IL1A	IFNG	CSF1R	IL7R	GHR	BMP5	BMP3	BMP6	NGF	TNFSF4	ACVRL1	IL21	IL3RA	IL22	CXCR4	IL23R	CXCL12	TNFRSF21	CD40	IL18RAP	IL25	IL21R	IL12RB1	IL12RB2	IFNGR1	BMPR1B	IL23A	BMPR1A	BMPR2	EPOR	IL17RA	FASLG	IL1RL1	IFNK	CCR9	IL20RA	IL20RB	IL19	GDF5	CCR8	EDA	CCR6	EDA2R	CX3CR1	CSF2RA	CCL1	IL11	IL33	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	CCL20	IFNB1-4	IL15	IL10RB	IL3	IL7	ACVR1B	GDF9	INHA	FAS	LTA	LEPR	CX3CL1	CCL23;CCL15	TNFRSF11B	TNFRSF11A	IFNAR2	IL1R1	IFNGR2	CCL5	ACVR1	IL31RA	CCL13;CCL2	IFNAR1	PRL	IL2RG	IL17D	TGFB2	GDF3	IL4R	PRLR	IL17C	TGFB1	TGFB3	IL17B	TGFBR2	CXCL10	IL2RA	IL2RB	CSF3	CSF2	LEP	CCR3	CCR2	AMH	IL13	CCL28	ACVR2B	IL18R1	IL5RA	CSF2RB	CCL3L1;CCL3L3;CCL3;CCL18	CCL4L2;CCL4L1;CCL4	IL9	TNFRSF25	BMP7	GDF15	IL5	CXCL14	CXCL9	CSF1	IL1R2	CXCL17	IL17F	PPBP	IL17A	TNFSF15	IL24	BMP10	CCR10	CCR1	NODAL	XCR1	IL1RN	ACKR3-2	CCR7	CCR5	CCR4	TNFRSF19	LIFR	INHBA	CXCR1	CXCR2	TNFSF10	CXCL5;CXCL6	
PEROXIREDOXIN 2 INDUCED OVARIAN FAILURE%WIKIPATHWAYS_20260910%WP4873%HOMO SAPIENS	Peroxiredoxin 2 induced ovarian failure	STAR	HSD3B1;HSD3B2	CYP11A1	BAX	PRDX2	CASP3	MAPK10	PARP2	
TRANSCRIPTIONAL REGULATION OF MEMORY B CELL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP5491%HOMO SAPIENS	Transcriptional regulation of memory B cell differentiation	TCF4	MEF2B;BORCS8-MEF2B	CD79B	CD79A	LOC102723996;ICOSLG	SPIB	SLAMF1	POU2AF1	SPI1	STAT3	TLR10	EZH2	CDKN1A	CDKN1B	IL6	POU2F2	CCND3	LYN	CCND2	SYK	BCL2L1	CD40	IL21R	MYC	ID3	TLR1	TNFRSF13C	TLR9	TLR5	TLR8	TLR6	TLR2	TLR7	TLR4	TLR3	BCL6	IRF4	IRF8	BCR	E2F1	STAT6	CDKN2A	IL4R	MEF2C	NFKB1	
ACETYLCHOLINE SYNTHESIS%WIKIPATHWAYS_20260910%WP528%HOMO SAPIENS	Acetylcholine synthesis	PDHA1	CHAT	PEMT	CHKA	ACHE	PCYT1A	
GLP 1 FROM INTESTINE AND PANCREAS AND ROLE IN GLUCOSE HOMEOSTASIS%WIKIPATHWAYS_20260910%WP5452%HOMO SAPIENS	GLP 1 from intestine and pancreas and role in glucose homeostasis	SLC2A1	GCG	GLP1R	PCSK1	INS;INS-IGF2	PCSK2	
VEGFA VEGFR2 SIGNALING%WIKIPATHWAYS_20260910%WP3888%HOMO SAPIENS	VEGFA VEGFR2 signaling	PRDX6	ACTG1	GJA1	MYO6	PRKAA2	EIF3H	EIF3F	CACNA2D1	EIF3D	FN1	CCND1	SELE	CNP	CLTC	RPS6KA5	AP2A1	MKNK1	EPRS1	BMP2	NAPA	MAPK8	ARF4-1	WASF1-1	PLA2G4A	ARPC5L	AP2S1	RPL7	FADD	LUC7L	IER5	SND1	TPM3	EWSR1	BIN1	GPX1	RPL27	PRKD2	RPL26	FLII	NCF2	ABCF2-H2BE1;ABCF2	GIGYF2	PRRC2C	TRIP4	NR4A2	LARP7	NR4A1	RPL5-1	GIPC1	MMP10	FARSB	KCNC3	EEA1	PBK	MMP14	TBCA	MOV10	RPLP2	CGNL1	NCL-1	SSR4	SSR3	TAL1	KANK1	SLC7A1	APOLD1	FGD5	BRD4	AKT1	CTNND1	SH3BGRL3	PLOD3	MTOR	RPL10A	TMSB10	SEMA6D	ARMCX1	RAB37	FSCN1	GSK3B	DSC1	HDAC1	LRRC59	PIK3R2	STIP1	PIK3R1	HLX	TXNDC5	QKI	PTMA	RCAN1	PNP-1	MAP2K2;MAP2K1	TFCP2	SYNJ1	EPHA2	MAPK1	RCAN2	RAC1	TPP1	NRARP	CAPZB	RHOJ	ADAMTS1	ARF6	ADAMTS9	MAPK3	DKK1	ACP1	PRKG1	MAP2K4	SARS1	CREBBP	RPL13A-1	STAT1	SLC25A11	PBXIP1	MYO1C	PRKCD	DNAJB4	STAT3	SLC25A25	CDC42BPB	GAB1	PTPN11	PTPN14	TPCN2	PTPN9	P4HB	TRAF3IP2	RPL18A	UBAP2L	CHAC1	RPS6KB1	TMEM170A	TNXB	INPP4B	GRB2	KATNAL2	ZNF555;ZNF57;ZNF556	PFN1	BCL2L1	ATP6V0D1	FXR2	SHC1-1	SHC2	ATP6V1E1	DHX36	MICAL2	CALU	CXCL8	DHX29	NRP2	FAF1	CCDC124	HERPUD1	CLIC1	FJX1	NEXN	HMGB1-1	CRIP2	GPC1	EPS15	PRKRA	COPG1	FHOD1	TMOD1	TMOD3	PSMD11	HTRA1	SCUBE2	ZC3H15	DNAJA1-1	GRSF1	C15orf39	RND1	LRRFIP2	ARHGEF15	SHROOM2	PRKCI	EPN1	RCN1	USP10	PRKCB	FAM120A	PRKCE	PDE4DIP	PRKCA	FMNL3	ALDOA	EZR	PRKD1	NOTCH4	PRKCZ	HSP90AA1	TEAD4	CCT7	JAG1	TAOK2	NFATC1	NOS3	FOXO3	HGS	SET-1	PIK3CA	FLT1	PGF	TXN	SPIRE1	DLL4	MAPK9	PLA2G5	MAPK14	MAPK12	CTNNB1	TRPC3	TRPC1	EGR1	FOXO4	EGR3	CREB1	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	MDM2-2	CYCS-1	ABL1	PPP1CA	FAS	FBXW11	FOXO1-1	ACACA	FYN	PRDX2	ACOT9	CCL13;CCL2	STAT6	OCLN-1	ARNT	NFKB1	AFDN	NR4A3	CCN1	PLAU	CSRP1	CCN2	NUMB	IDH2	ARRB2	TKT	MMP2	TXNIP	CAMKK2	NCF1	HDAC4	HDAC5	HDAC9	HDAC7	VEGFA	MEF2C	MYL2	ADAM10	BMP10	HRAS	TFAM-1	PTGS2-2	ACKR3-2	NCK1	ETS1	ELOA	MYH9	PTPRZ1	ENG	NAP1L1	MAPKAPK5	LDHA	GAPDH-1	PRKAA1	PGK1	CCRL2	ATF2	ELK1	CBL	RELA	PLAUR	F3	ADAM9	SRPK1	NFKBIA	PTPN6	PSMD4	KDR	SRP54	LMAN1	ATF6	ATF4	EIF2AK3	RICTOR	NOX4	TUBA1C	FLNB	SIAH2	PPM1G	PPP3CA	PLCB3	DUSP5	RBM39	MAP2K7	EIF4E	MAP2K6	MAP2K3	JUN	BCL2	RAF1	SMARCA2	EPHB2	MAP3K5	CYBB	ERN1	CALR-1	FHL2	AMOT	RACK1	CDH5	HBEGF	TUBB4A;TUBB;TUBB8B;TUBB8	ANXA1	RHOC	CFL1	MAPKAP1	SLC8A1	ITCH	PTK2B	IQGAP1	IGFBP3	ADRB2	KL	NFATC2	STAM	VPS39	BIRC5	PTPRJ	CAPN2	RPS11	VCL	PXN	RAP1B	RAP1A	CAV1	PTK2	ITGB1	ITGB5	ITGB3	SDF2L1	SHB	ITGAV	SDCBP	HYOU1	BMX	PDPK1	ELOC-1	VAV2	RAPGEF1	ERG	CRK	ROCK1	ROCK2	SRC	CDC42	PAK1	CSK	PAK2	LDB2	BCAR1	YWHAE	DECR1	SRF	MMRN2	MAPKAPK2	MYH11	ACACB	PPP2CB;PPP2CA	CTNNA1	PABPC1;PABPC3	EIF4G2	DNAJB9	EIF2A	RPS6	INPP5K	PDIA6	OCRL	CSRP2	PTPN1	ICAM1	RAB5A	FGB	FGA	ASCC3	FGG	GRB10	HBD;HBB	DOK1	SOD2	TNFRSF25	ALB	FUT1	GATA2	BSG	EPB41	PLCG1	EIF4G1	RHOA	GLUD1;GLUD2	S1PR1	P4HA2	LIMK1	MLST8	IGFBP7	FRS2	HSPA1A;HSPA1B	HSPB1	NDRG1	DPM1	RAB4A	AKT1S1	RAB11A	PGD	
UROTENSIN II MEDIATED SIGNALING%WIKIPATHWAYS_20260910%WP5158%HOMO SAPIENS	Urotensin II mediated signaling	JAK2	IRF3	MAPK9	MAPK3	CREBBP	COL1A1	MAPK14	ICAM1	STAT3	IKBKB	UTS2R	PTPN11	EP300	CTNNB1	CHUK	IL6	MMP2	RELA	CASP9	MMP9	CASP3	FN1	ABCA1	COL3A1	VCAM1	HMOX1	NCF1	NCF4	PTEN	TNF	CCNE1	CYBA	HDAC5	ACTA2	EGFR	ESPL1	GSK3A	NOX4	TRPC4	HSPA2	IL1B	CDK2	MAPK8	CDK1	CAMK2A	ALOX5	BAX	NPPA	RHOA	NCF2	DDIT3	BCL2	SMAD2;SMAD3	NPPB	PRKACA-1	AIFM2	COL2A1	AKT1	CYBB	AGTR1	PCNA	GSK3B	FSCN1	TGFB1	NFKB1	MAPK1	
MECP2 AND ASSOCIATED RETT SYNDROME%WIKIPATHWAYS_20260910%WP3584%HOMO SAPIENS	MECP2 and associated Rett syndrome	APOC2	MECP2	TET1	REST	CSRP1	SMC3	DLX5	SGK1-1	IGF1R	FUS	DHX9	OPRK1	SP1	CREB1	CNP	YBX1	PTEN	FGF2	CEBPD	NCOR1	MBP	FGF3	FGF4	FGF5	FKBP5	HNRNPH1	E2F1	CTCF	MEF2C	IGF1	GRID1	MYT1	MAG	PSIP1	RBFOX1	GRIA1	GPRIN1	GRIA3	GAD1	SST	TET3	GRIA4	ARHGEF26	DLX6	IGF2	TET2	CAMK2A	NREP	FUT8	MPP1	PRPF38A	EZH2	POU4F1	UBE3A	HNRNPF	SP3	NF1	POU3F2	BDNF	FOXG1	GRIN1	TAP1	TAF1	AKT1	MTOR	BCL6	SIN3A	HDAC1	GAMT	RPS6	TARDBP	GABRR2	CDON	
MIR 517 RELATIONSHIP WITH ARCN1 AND USP1%WIKIPATHWAYS_20260910%WP3596%HOMO SAPIENS	miR 517 relationship with ARCN1 and USP1	CDKN1A	USP1	ID1	ID2-1	ARCN1	
WNT BETA CATENIN SIGNALING IN LEUKEMIA%WIKIPATHWAYS_20260910%WP3658%HOMO SAPIENS	Wnt beta catenin signaling in leukemia	DKK1	WIF1	PPARD	WNT1	CTNNB1	RUNX1T1	JUP	ZBTB16	FZD6	CCND1	MYC	FLT3	LRP6	SALL4	AKT1	AXIN2	LEF1	RARA	GSK3B	LRP5	CSNK1A1	PYGO1	PML	BCL9	APC	
MEVALONATE ARM OF CHOLESTEROL BIOSYNTHESIS PATHWAY%WIKIPATHWAYS_20260910%WP4190%HOMO SAPIENS	Mevalonate arm of cholesterol biosynthesis pathway	IDI1	MVK	IDI2	ACAT1	ACAT2	HMGCL	MVD	HMGCR	HMGCS1-1	PMVK	FDFT1	FDPS	GGPS1	
ACETAMINOPHEN IN ANALGESIA AND ANTIPYRESIS%WIKIPATHWAYS_20260910%WP5444%HOMO SAPIENS	Acetaminophen in analgesia and antipyresis	KCNQ3	FAAH	CACNA1H	PTGS1	PTGS2-2	TRPA1	TRPV1	KCNQ2	HTR1A	
SNARE COMPLEX MACHINERY IN EXOCYTOSIS%WIKIPATHWAYS_20260910%WP5621%HOMO SAPIENS	SNARE complex machinery in exocytosis	VAMP2	NAPA	STXBP1	CACNA1B	CACNA1A	SNAP25	RAB3A	CPLX1	RPH3A	RIMS1	STXBP5	STXBP6	SYT1	NSF	UNC13A	SYP	GDI1	
OSTEOBLAST SIGNALING%WIKIPATHWAYS_20260910%WP322%HOMO SAPIENS	Osteoblast signaling	ITGB3	FGF23	IBSP	COL1A1	PDGFRA	ITGAV	PDGFB	PDGFRB	PTH1R	SLC17A2	TNFSF11	PTH	TNFRSF11B	
TRANSCRIPTIONAL ACTIVATION BY NRF2 IN RESPONSE TO PHYTOCHEMICALS%WIKIPATHWAYS_20260910%WP3%HOMO SAPIENS	Transcriptional activation by NRF2 in response to phytochemicals	PRKCA	GSTA3;GSTA5;GSTA1;GSTA2	GCLM	NQO1	HMOX1	MAPK8	MAF	EPHB2	NFE2L2	KEAP1	SLC7A11	PIK3CA	CEBPB	GCLC	AIMP2	
GLYCINE METABOLISM INCLUDING IMDS%WIKIPATHWAYS_20260910%WP5028%HOMO SAPIENS	Glycine metabolism including IMDs	ISCU	SHMT1	AMT	LIPT2	LIPT1	PNPO	GLDC	DLD	GLRX5	GCSH-3	IBA57	HSCB	LIAS	NFU1	BOLA3	
WNT SIGNALING AND PLURIPOTENCY%WIKIPATHWAYS_20260910%WP399%HOMO SAPIENS	Wnt signaling and pluripotency	MAPK9	WNT11	WNT7B	MAPK10	EP300	PPARD	CTNNB1	CCND3	CCND2	FOSL1	CCND1	MYC	TP53	LRRK2	AXIN2	CTBP2	CTBP1	NKD1	NKD2	SOX2	JUN	ESRRB	MMP7	PPP2CB;PPP2CA	FZD1	FOXD3	FZD3	PAFAH1B1	WNT3A	WNT5A	WNT7A	WNT3	LRP6	CTNND1	GSK3B	NFYA-1	PPP2R1B	PPP2R1A	NLK	PPP2R2A;PPP2R2D	MAP3K7	MAP2K4	CREBBP	PRKCD	PLAU	TPTEP2-CSNK1E;CSNK1E	TCF7	LDLR	DVL1	DVL2	DVL3	FZD10	AXIN1	LEF1	PRKCG	PRKCI	TCF7L2	PRKCH	TCF7L1	WNT5B	PRKCB	PRKCE	APC	PRKCA	POU5F1;POU5F1B	PRKCQ	PRKD1	CD44	NANOG;NANOGP8	PRKCZ	WNT6	WNT1	WNT2	RHOA	RACGAP1	WNT4	WNT10B	WNT10A	FZD2	FZD5	FZD4	FZD7	FZD6	FZD9	FBXW2	FZD8	PPM1J	PPP2R3B	PTPA	WNT2B	PPP2R3A	PPP2R2C	PPP2R2B	ZBTB33	PPP2R5E	PPP2R5C	WNT9B	WNT16	LRP5	
SMITH MAGENIS AND POTOCKI LUPSKI SYNDROME COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5381%HOMO SAPIENS	Smith Magenis and Potocki Lupski syndrome copy number variation	SMCR8	GAS8	RMND5A	GPS1	MIEF2	LDHA	RASD1	NT5M	PRKAA1	FNIP1	CLUAP1	FNIP2	FBXL13	MYO16	MYO15A	DRG2	CCDC65	GPR85	CLOCK	RELA	APP	PRKAG2	ROCK1	MYC	PRKAB1	TNFRSF13B	ATG13	BIRC2	CREB1	ULK1	CLTC	CLTA	TNF	TP53	BLM	ARNTL	TOLLIP	PARD3	MAP3K14	MYD88	PARD6B	IL1B	NR1H3	PER1	RNF41	CDK1	BAX	WWTR1	FOXA1	SREBF1	PEMT	NR1H2	FLII	JUN	APBB1	FOXA2	RAI1	COPS6	MTOR	PRDM1	NFKB1	CRY2	CRY1	ETV5	PPP1R12A	ATG101	STAT3	C9orf72	PPP1R14A	RAB8A	RB1CC1	CARM1	RRAGA	IFT172	USP8	IFT74	TRAF3IP1	PTEN	TLR4	FHOD1	ARMC8	PRKN	IFT88	COPS7A	MED9	HES6	PRKCI	CLEC16A	GRIP1	SHMT1	YAP1-1	WDR26	RHOA	CLTB	MKLN1	GID4	MAEA	TTC30A;TTC30B	PCK1	TFE3	CFL2	IFT80	RPTOR	FERD3L	HSPB11	ALKBH5	MPRIP	IFT20	LIMK1	DENR	COPS4	MIGA2	COPS3	IFT22	MIGA1	COPS5	DRC3-1	IFT81	MLST8	TOM1L2	COPS2	IFT27	RANBP9	LLGL1	COPS8	IQCA1	BCL2L11	DRC7	TTC26	IFT46	RAB10	ATPAF2-2	PLD6	G6PC1	RAB39B	BCL6	HBP1	DRC1	IFT52	GDI2	IFT57	IRF8	WDR41	FLCN	EFCAB2	RMI2	ARG2	RMI1	TOP3A	ITPK1	TFEB	IQCD	TCTE1	IQCG	
DNA IR DAMAGE AND CELLULAR RESPONSE VIA ATR%WIKIPATHWAYS_20260910%WP4016%HOMO SAPIENS	DNA IR damage and cellular response via ATR	MCM2	SMARCC2	UPF1	DCLRE1A	UBE2D3-1	SEM1	UIMC1	TOPBP1	IKBKG	HUS1	POLN	RECQL	EEF1E1	ABRAXAS1	MRE11	BRCC3	PPM1D	BRCA1	RECQL5	RBBP8	CLSPN	TDP1	RFWD3-2	CLK2	CHEK2	CHEK1	MCPH1	NBN	SMC1A	CDC25C	CDC45	PLK1	SP1	FANCD2	BRCA2	TP53	MDM2-2	E2F1	BARD1	ATRIP	MSH2	RPA2	XPA	PML	BRIP1	RAD52	RAD50	FANCI	RAD51	CDK2	RNF8	FANCA	PRKDC	CDK1	RAD17	PALB2	PARP1	RAD1	ATM	ATR	MDC1	RAD9A	FEN1	TP53BP1	POLB	EXO1	SMARCAL1	TRIM28	WRN	BCL6	USP1	PCNA	XRCC5	RMI1	RPA1	TOP3A	FOXM1	CEP164	MLH1	HERC2	
EDA SIGNALING IN HAIR FOLLICLE DEVELOPMENT%WIKIPATHWAYS_20260910%WP3930%HOMO SAPIENS	EDA signaling in hair follicle development	EDA	DKK1	DKK4	WNT3	SOSTDC1	SHH	BMP1	LTB	GLI1	RELB	EDARADD	PTCH1	EDAR	
SLEEP REGULATION%WIKIPATHWAYS_20260910%WP3591%HOMO SAPIENS	Sleep regulation	NLGN1	HTR2A	AHCY	PTGDR	GHRH	GHRL	PTGDS	HCRTR2	NPY2R	HCRTR1	UTS2R	ADORA1	FOS	DLAT	CHRNB2	IL6	CACNA1I	SLC29A1	MTNR1B	MRGPRX3;MRGPRX4;MRGPRX1;MRGPRX2-3	IL18	STAR	NPAS2	OXT-1	ADA	DRD1	DRD2	DRD3	ADORA2A	TH	GRIN2A	BTBD9	OXTR	CST3	NPS	CRH	
FBXL10 ENHANCEMENT OF MAP ERK SIGNALING IN DIFFUSE LARGE B CELL LYMPHOMA%WIKIPATHWAYS_20260910%WP4553%HOMO SAPIENS	FBXL10 enhancement of MAP ERK signaling in diffuse large B cell lymphoma	PCGF1	H3-3A	MACROH2A2	H2AZ2;H2AZ1	MACROH2A1	H2AJ	MAPK3	EED	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	EZH2	DUSP6	BCOR	H2AB2;H2AB3;H2AB1	BCL6	KDM2B	MAPK1	SUZ12	RNF2	
VISUAL CYCLE%WIKIPATHWAYS_20260910%WP5534%HOMO SAPIENS	Visual cycle	LRAT	ABCA4	RDH11	RHO	RBP3	RDH8	RLBP1	RDH10	OPN1MW3;OPN1MW2;OPN1MW;OPN1LW	RBP1	OPN1SW	RDH5	RPE65	RDH12	
GPCRS CLASS B SECRETIN LIKE%WIKIPATHWAYS_20260910%WP334%HOMO SAPIENS	GPCRs class B secretin like	VIPR1	GHRHR	ADCYAP1R1	CALCRL	VIPR2	GIPR	ADGRE5	GCGR	GLP2R	SCTR	PTH2R	CRHR1	CRHR2	ADGRE1	ADGRL2	PTH1R	ADGRG2	ADGRL3	CALCR	ADGRL1	ADGRL4	GLP1R	
DOPAMINE METABOLISM%WIKIPATHWAYS_20260910%WP2436%HOMO SAPIENS	Dopamine metabolism	MAOB	TYR	COMT	PRKACA-1	DDC	MAOA	NQO1	SOD1	PPP2CB;PPP2CA	PRKACB-1	TH	
BMP2 WNT4 FOXO1 PATHWAY IN PRIMARY ENDOMETRIAL STROMAL CELL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP3876%HOMO SAPIENS	BMP2 WNT4 FOXO1 pathway in primary endometrial stromal cell differentiation	SMAD9	BMP2	SMAD5	DKK1	SST	LEFTY2;LEFTY1	BCL2L11	CTNNB1	WNT4	DCN	SMAD1	SFRP1	FOXO1-1	
REGUCALCIN IN PROXIMAL TUBULE EPITHELIAL KIDNEY CELLS%WIKIPATHWAYS_20260910%WP4838%HOMO SAPIENS	Regucalcin in proximal tubule epithelial kidney cells	CASP8	BAX	MCU	TNFRSF1A	FFAR3;GPR42	TRPV5	TNFSF11	SMAD4	CASP9	CALCA	TGFBR1-1	G3BP1	CASP3	SMAD2;SMAD3	RAF1	APAF1	NOS1	AKT1	MAP3K5	MTOR	PPP3R1	PDE1B	ACTA2	CRYZL2P-SEC16B;SEC16B	RGN	PTH	BRAF	BAK1	PIK3CA	TGFB1	MAPK1	
ETHYLMALONIC ENCEPHALOPATHY%WIKIPATHWAYS_20260910%WP5030%HOMO SAPIENS	Ethylmalonic encephalopathy	SUOX	ETHE1	TST	
PEROXISOMAL BETA OXIDATION OF TETRACOSANOYL COA%WIKIPATHWAYS_20260910%WP1941%HOMO SAPIENS	Peroxisomal beta oxidation of tetracosanoyl CoA	SCP2	ACAA1-1	ACOX1	HSD17B4	
NIPBL ROLE IN DNA DAMAGE CORNELIA DE LANGE SYNDROME%WIKIPATHWAYS_20260910%WP5119%HOMO SAPIENS	NIPBL role in DNA damage Cornelia de Lange syndrome	RNF168-1	RNF8	CBX3-1	NIPBL	ATM	ATR	MDC1	
ANK2 PATHWAY IN EPILEPSY DEVELOPMENT%WIKIPATHWAYS_20260910%WP5557%HOMO SAPIENS	ANK2 pathway in epilepsy development	PRICKLE1	ANK3	SEMA3A	SNAP25	SCN2A	ATF6	ATF4	KCNQ2	DNM1L	MAPT	CSNK2A1;CSNK2A3	EIF2AK3	PRRT2	EIF2A	CSNK2A2	SCN5A	BRSK1	SPTBN4	CSNK2B	BRSK2	DDIT3	ANK2	L1CAM	SPTAN1	
SELENIUM METABOLISM AND SELENOPROTEINS%WIKIPATHWAYS_20260910%WP28%HOMO SAPIENS	Selenium metabolism and selenoproteins	RPL30	TXNRD2	SELENBP1	SEPHS1	PSTK	EEFSEC	POU2F1	SECISBP2	TRNAU1AP	SARS1	SEPSECS	TXNRD1	SARS2	SCLY	GPX6	SP3	FOS	GPX1	GPX4	RELA	JUN	TXNRD3	CREM	SEPHS2	FABP1	SELENOO	SELENON	SELENOS	SP1	SELENOT	SELENOK	SELENOI	CTH	SELENOP	NFE2L2	DIO1	DIO3	NFKB1	
LINOLEIC ACID OXYLIPIN METABOLISM%WIKIPATHWAYS_20260910%WP5137%HOMO SAPIENS	Linoleic acid oxylipin metabolism	ALOX15	ALOX5	EPHX2	
HEPATITIS C AND HEPATOCELLULAR CARCINOMA%WIKIPATHWAYS_20260910%WP3646%HOMO SAPIENS	Hepatitis C and hepatocellular carcinoma	IL6R	MAPK3	JAK1	PODXL	MAPK14	STAT3	PTPN11	MMP1	CDKN1A	VAV2	IL6	BRCA1	RRM2-1	GRB2	CASP9	SOS1	BCL2L1	CASP3	CXCL8	CCND1	MYC	NOS2	BIRC3	COL4A2	TP53	HNF1A	LEF1	UCHL1	CASP7	E2F2	VEGFA	MAPK8	HIF1A	CD44	MYOF	CTTN	FRZB	PTGS2-2	SMAD4	JUN	TGFBR1-1	SMAD2;SMAD3	BIRC5	AKT1	FASLG	CXCR1	TGFB1	NFKB1	RAC1	
2Q11 2 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5221%HOMO SAPIENS	2q11 2 copy number variation syndrome	ZP2	MAPK3	ANKRD39	LMAN2L	CIAO2A	DUSP2	NCAPH	PARL	RHOA	CIAO1	FAM178B	ITPRIPL1	TMEM127	COX11	CIAO2B	CNNM3	CNNM4	FER1L5	STARD7	SEMA4C	ASTL	NEURL3	KANSL3	PLXNB2	MMS19	ERBB2	ADRA2B	COL2A1	ANKRD23	MAPK1	SNRNP200	
MAPK AND NFKB SIGNALING INHIBITED BY YERSINIA YOPJ%WIKIPATHWAYS_20260910%WP3849%HOMO SAPIENS	MAPK and NFkB signaling inhibited by Yersinia YopJ	RAF1	CHUK	TRAF6	IKBKG	RRAS	MAP2K6	MAP3K1	NFKBIA	NFKB1	IKBKB	MAPK1	MAP3K14	
CELL DIFFERENTIATION INDEX%WIKIPATHWAYS_20260910%WP2029%HOMO SAPIENS	Cell differentiation index	TLX3	TLX2	TLX1	LEFTY2;LEFTY1	STAT3	HDAC5	SRF	
MAMMARY GLAND DEVELOPMENT EMBRYONIC DEVELOPMENT STAGE 1 OF 4%WIKIPATHWAYS_20260910%WP2813%HOMO SAPIENS	Mammary gland development embryonic development stage 1 of 4	CCND1	CDH1	MYC	TERT	NRG3	ALPL	ERBB4	TNF	AKT1	ZEB2	CLDN4	SFRP1	ITGA6	TGFB1	ITGB1	
PROLINE AND HYDROXYPROLINE PATHWAYS%WIKIPATHWAYS_20260910%WP5026%HOMO SAPIENS	Proline and hydroxyproline pathways	ALDH4A1	PEPD	PRODH;LOC102724788	OAT	PYCR1	
DNAJB1 PRKACA FUSION IN FIBROLAMELLAR LIVER CANCER%WIKIPATHWAYS_20260910%WP5514%HOMO SAPIENS	DNAJB1 PRKACA fusion in fibrolamellar liver cancer	DNAJB1	GNAS-1	HDAC7	PRKACA-1	SIK3	SIK2	CRTC2	CREB1	HDAC4	HDAC5	SIK1;SIK1B	
AIRWAY SMOOTH MUSCLE CELL CONTRACTION%WIKIPATHWAYS_20260910%WP4962%HOMO SAPIENS	Airway smooth muscle cell contraction	ADRB2	MYLK	PPP1CB	PPP1R14A	RHOA	GNAQ	PLCB1	RYR1	CD38	IL13	ROCK1	CALM1	ROCK2	GDI1	ITPR3	MYL1	
UTERINE NATURAL KILLER CELLS AND PROGESTERONE ESTROGEN AND CHORIONIC GONADOTROPIN%WIKIPATHWAYS_20260910%WP5569%HOMO SAPIENS	Uterine natural killer cells and progesterone estrogen and chorionic gonadotropin	CXCL10	IL2RB	MAPK3	JAK1	MAP2K4	ITGA4	MAPK11	JAK3	IL6	CXCR4	NR3C1	CXCL12	CX3CL1	STAT5A	STAT5B	CCL3L1;CCL3L3;CCL3;CCL18	PIBF1	IL10	BCL2	CXCL8	CCL4L2;CCL4L1;CCL4	VCAM1	ESR2	IL4	PGR	NCR1-1	IFNG	MRC1	CCL5	MADCAM1	GAB3	CD69	TNF	CCL8	IL15	GATA2	CCL13;CCL2	ANGPT2	IL3	ANGPT1	IL2RG	CXCR3	VEGFA	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	MCL1	CXCL11	SELL	
TUMOR SUPPRESSOR ACTIVITY OF SMARCB1%WIKIPATHWAYS_20260910%WP4204%HOMO SAPIENS	Tumor suppressor activity of SMARCB1	SMARCD1	H3-3A	SMARCD2	CDK6	SMO	SMARCD3	CDK4	SMARCC1	SMARCC2	ACTL6A	ARID1B	EZH2	RB1	SMARCB1	SMARCE1	GLI1	PTCH1	SUZ12	EED	GLI4	ARID1A	DPF1	SMARCA4	GLI2	DPF2	ACTL6B	DPF3	GLI3	CDKN2A	RBBP4	
PILOCYTIC ASTROCYTOMA%WIKIPATHWAYS_20260910%WP2253%HOMO SAPIENS	Pilocytic astrocytoma	RAF1	KRAS	GRB2	NRAS	BRAF	SOS1	HRAS	PTPN11	NF1	
BENZO A PYRENE METABOLISM%WIKIPATHWAYS_20260910%WP696%HOMO SAPIENS	Benzo a pyrene metabolism	CYP1B1	AKR1A1	CYP1A1	EPHX1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
AEROBIC GLYCOLYSIS AUGMENTED%WIKIPATHWAYS_20260910%WP4628%HOMO SAPIENS	Aerobic glycolysis augmented	SLC2A1	GPT	ALDOA	LDHA	GAPDH-1	PKM	PGK1	ENO1	HK1	PFKM	PGAM2	TPI1	GPI	
SARS COV 2 MITOCHONDRIAL CHRONIC OXIDATIVE STRESS AND ENDOTHELIAL DYSFUNCTION%WIKIPATHWAYS_20260910%WP5183%HOMO SAPIENS	SARS CoV 2 mitochondrial chronic oxidative stress and endothelial dysfunction	TRAF6	NLRX1	TERF2IP	TOMM70	MAVS	STING1	REN	AGT	RPS6KA1	IL6	BCS1L	TRAF3	IL18	TERF2	ECSIT	TNF	PHB	ACE2	ACE	ACAD9	SIRT6	NDUFAF2	NLRP3	NDUFAF1	NFKB1	NOX1	
ESTROGEN SYNTHESIS AND METABOLISM%WIKIPATHWAYS_20260910%WP5276%HOMO SAPIENS	Estrogen synthesis and metabolism	CYP19A1	HSD17B2	HSD17B3	COMT	HSD17B10	CYP2C9;CYP2C19	HSD17B7	CYP1A2	HSD17B4	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	HSD17B1	CYP1B1	HSD17B8	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	
TH17 CELL DIFFERENTIATION PATHWAY%WIKIPATHWAYS_20260910%WP5130%HOMO SAPIENS	Th17 cell differentiation pathway	JAK2	IL6R	IL2RA	JAK1	RXRA	STAT1	MAPK14	CD3G	STAT3	CD3E	IKBKB	TYK2	CD247	FOS	IL6	CD3D	CLOCK	IL27RA	STAT5A	NFKBIA	NR1D1	RUNX1	IL2	IL4	IL27	IFNG	LAT	GATA3	CD4	AHR	ARNTL	IL17F	NFIL3	IL17A	IL1B	PRKCQ	PPP3CA	PER1	MAPK8	HIF1A	PLCG1	HSP90AA1	IL21	IL22	IL23R	RORC	JUN	RORA	TGFBR1-1	HLA-DMA	TBX21	SMAD2;SMAD3	IL21R	LCK	IFNGR1	NFATC1	FOXP3	IL23A	MTOR	IRF4	RARA	STAT6	IL4R	TGFB1	ZAP70	SOCS3	NFKB1	CRY1	MAPK1	
GASTRIN SIGNALING%WIKIPATHWAYS_20260910%WP4659%HOMO SAPIENS	Gastrin signaling	MAPK9	LAMTOR3	MAPK14	ATF2	ELK1	IKBKB	CTNNB1	CHUK	CDKN1A	CDKN1B	FOS	RELA	CRK	EGR1	NFKBIA	CASP3	ROCK1	SRC	CDC42	CCND1	PAK1	MYC	BIRC2	BIRC3	CREB1	BCAR1	KIT	TCF4	BMP2	MAPK8	YES1	ANXA2	IRS1	PRKD2	SLC9A1	FOXO1-1	JUN	MMP7	SLC9A3	RAF1	CDH1	MAP3K11	MEF2D	GAST	FYN	AKT1	MTOR	ARHGEF28	CHGA	GSK3B	HDC	RPS6	PIK3R2	PIK3R1	NFKB1	RHOD	MAP2K2;MAP2K1	KAT5	MAPK1	RAC1	JAK2	EIF4EBP1	MEF2B;BORCS8-MEF2B	MAPK3	KLF4	RHOB	SERPINE1	BAD	PRKCD	STAT3	PTPN11	ARRB1	ARRB2	RPS6KB1	GRB2	SOS1	BCL2L1	SHC1-1	CXCL8	IL2	SP1	HDAC7	EGFR	VEGFA	MEF2C	PRKCH	PRKCE	PRKCA	PRKCQ	PRKD1	PLCG1	SERPINB2	CD44	PIK3R3	ELAVL1	HRAS	RHOA	GNAQ	TJP1	KRAS	PTGS2-2	CLDN1	JAG1	PRKACA-1	BIRC5	FOXO3	PXN	CCKBR	CDKN2A	PTK2	PIK3CA	PPARG	ITGB1	
ALANINE AND ASPARTATE METABOLISM%WIKIPATHWAYS_20260910%WP106%HOMO SAPIENS	Alanine and aspartate metabolism	GOT1-1	PC	GPT	ASL	ASPA	GAD1	DARS1	GOT2-1	GAD2	ABAT	AGXT	ASS1	
HOST PATHOGEN INTERACTION OF HUMAN CORONAVIRUSES APOPTOSIS%WIKIPATHWAYS_20260910%WP4864%HOMO SAPIENS	Host pathogen interaction of human coronaviruses apoptosis	APAF1	BAD	CASP8	MAPK14	BAX	MAPK12	TNF	MAPK13	BCL2L11	MAPK11	AKT1	FADD	FASLG	CASP7	BBC3	CASP9	BID	MCL1	BCL2L1	CASP3	BCL2	
DNA DAMAGE RESPONSE%WIKIPATHWAYS_20260910%WP707%HOMO SAPIENS	DNA damage response	RB1	CDKN1A	CDKN1B	MRE11	HUS1B	BRCA1	BBC3	CASP9	PIDD1	CCND3	CCND2	CHEK2	CASP3	SESN1	CHEK1	TLK2	CCND1	TLK1	MYC	NBN	APAF1	RFC1	SMC1A	CDC25C	CDC25A	DDB2	CREB1	CCNE2	RRM2B	FANCD2	CCNE1	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	TP53	MDM2-2	CYCS-1	CCNB3	CCNB2	CCNB1	ABL1	E2F1	PMAIP1	SFN	BID	ATRIP	GADD45B	GADD45A	RPA2	PML	GADD45G	RAD52	RAD50	CDK6	RAD51	CDK5	CDK4	CDK2	PRKDC	CDK1	RAD17	CASP8	FAS	BAX	RAD1	ATM	ATR	RAD9A	AKT1	
MICRORNA NETWORK ASSOCIATED WITH CHRONIC LYMPHOCYTIC LEUKEMIA%WIKIPATHWAYS_20260910%WP4399%HOMO SAPIENS	MicroRNA network associated with chronic lymphocytic leukemia	MCL1	ZAP70	BCL2	TP53	
EVOLOCUMAB MECHANISM TO REDUCE LDL CHOLESTEROL%WIKIPATHWAYS_20260910%WP3408%HOMO SAPIENS	Evolocumab mechanism to reduce LDL cholesterol	PCSK9	LDLR	
FLT3 P GLN640SERFSTER8 SIGNALING%WIKIPATHWAYS_20260910%WP5431%HOMO SAPIENS	FLT3 p Gln640SerfsTer8 signaling	CCR6	CCR5	FLT3	STAT3	
BETA GLOBIN GENE EXPRESSION REGULATION%WIKIPATHWAYS_20260910%WP5606%HOMO SAPIENS	Beta globin gene expression regulation	DNMT1	HDAC2	TAL1	PPARGC1A	CHD3	NR2C2	MYB	KLF1	HBG2;HBG1	LDB1	HDAC1	BCL11A	LMO2	MTA2	GATA1	NR2C1	HBD;HBB	GATAD2B	ZBTB7A	ZFPM1	KDM1A	
AXON GUIDANCE%WIKIPATHWAYS_20260910%WP5289%HOMO SAPIENS	Axon guidance	NRP1	DPYSL5	SEMA6C	ILK	UNC5D	ENAH	SEMA7A	NTN4	MYL12B	NTN3	EFNB1	ROBO1	ABLIM3	PLXNA1	LRIG2	SRGAP2	LRRC4C	PDPK1	NTNG2	RRAS	SLIT1	SLIT3	TRPC1	ROCK1	FES	SRC	CDC42	GDF7	CFL1	BOC	SHH	ARHGEF12	DCC	ABL1	RGMA	EFNA1	PARD3	RYK-1	L1CAM	PRKCA	RASA1	CDK5	GNAI1	SEMA3A	HRAS	PRKCZ	WNT4	CXCR4	CXCL12	EPHB1	NCK1	NGEF	PTCH1	PARD6A	DPYSL2	RAF1	MET	FZD3	BMPR1B	WNT5A	FYN	BMPR2	ROBO2	SLIT2	GSK3B	ITGB1	RHOD	SEMA5B	EPHA2	MAPK1	ROBO3	RAC1	
OXYTOCIN SIGNALING%WIKIPATHWAYS_20260910%WP2889%HOMO SAPIENS	Oxytocin signaling	PLCD1	GNAQ	OXTR	CD38	
OCTADECANOID FORMATION FROM LINOLEIC ACID%WIKIPATHWAYS_20260910%WP5324%HOMO SAPIENS	Octadecanoid formation from linoleic acid	ALOX12B	ALOX15	ALOXE3	GPX4	PTGS1	PTGS2-2	CYP2C9;CYP2C19	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	EPHX3	
PHASE I BIOTRANSFORMATIONS NON P450%WIKIPATHWAYS_20260910%WP136%HOMO SAPIENS	Phase I biotransformations non P450	PON3	ESD	CES2	PON2	CES5A	CES1	PON1	LIPA	
DISORDERS OF BILE ACID SYNTHESIS AND BILIARY TRANSPORT%WIKIPATHWAYS_20260910%WP5176%HOMO SAPIENS	Disorders of bile acid synthesis and biliary transport	SLC51A	SLC51B	AKR1D1	CYP7A1	ABCC3	ABCD3	ACOX2	ABCB4	ABCC4	SLC10A1	ABCC2	ATP8B1	CYP8B1	ABCB11	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	SLC27A5	SCP2	FABP6	HSD17B4	HSD3B7	CYP7B1	CYP27A1	AMACR	BAAT	SLC10A2	SLC27A2	ABCB1	
HEAD AND NECK SQUAMOUS CELL CARCINOMA%WIKIPATHWAYS_20260910%WP4674%HOMO SAPIENS	Head and neck squamous cell carcinoma	EIF4EBP1	PRKAA1	PDPK1	NUMB	CTNNB1	RB1	KEAP1	CDKN1A	RHEB	IGF1R	TP63	CSMD3	RELA	PRKAA2	SESN1	CCND1	TERT	STK11	ERBB2	BIRC2	MAPKAP1	PTEN	TP53	NFE2L2	SESN2	EGFR	E2F1	RICTOR	VEGFA	RPS6KB2	CDK6	NOTCH2	CDK4	NOTCH1	LTBR	NRAS	CASP8	HRAS	PIK3R5	FADD	CUL3	EIF4E	KRAS	SMAD4	TRAF3	AJUBA	RPTOR	IRF6	FGFR3	TSC2	MLST8	FGFR1	AKT2	FAT1	AKT3	MAML1	PIK3CB	AKT1	MTOR	PIK3CG	TSC1	REL	CDKN2A	FKBP1A	RPS6	PIK3R2	PIK3CA	PIK3R1	DDIT4	NFKB1	NFKB2	TGFBR2	
SUDDEN INFANT DEATH SYNDROME SIDS SUSCEPTIBILITY PATHWAYS%WIKIPATHWAYS_20260910%WP706%HOMO SAPIENS	Sudden infant death syndrome SIDS susceptibility pathways	GAPDH-1	REST	PPARGC1A	EP300	CPT1A	CHRNA4	CTNNB1	GJA1	LOC110384692;C4A;C4B_2;C4B	POU2F2	EGR1	CASP3	PRKACB-1	PRKAR2B	PRKAR2A	NKX3-1	VIPR1	ADCYAP1R1	SSTR2	PRKAR1B	VIPR2	PRKAR1A	SSTR1	SNAP25	CREB1	YBX1	ASCL1	TNF	YWHAE	HTR1A	YWHAB	YWHAQ	YWHAH	AVP	MAOA	NKX2-2	DDC	CTCF	SLC25A4	HTR2A	VAMP2	PBX1	IL1B	PLP1	TPH1	SLC1A3	POU3F2	CHRNB2	SOX2	BDNF	NR3C1	JUN	SLC9A3	TPH2	PHOX2B	PPARGC1B	TAC1	GRIN1	CREM	SLC6A4	NEUROD1	CHRNA7;CHRFAM7A	RUNX3	TH	BHLHE40	YWHAG	CHAT	HDAC1	NFYA-1	PAH	ECE1	YWHAZ	NFKB1	NFKB2	IL6R	TLX3	CREBBP	AR	MECP2	RET	IL6	TACR1	PKNOX1	IL13	KCNH2	HADHB-1	CHRNB4	TSPYL1	GPD1L-1	ADCYAP1	DLX2	IL10	CEBPB	DEAF1	SPTBN1	CXCL8	PHOX2A	FEV	CHRM2	CC2D1A	CDCA7L	EN1	ESR2	HTR3A	IL1A	NOS1AP	ATP1A3	SP1	KCNJ8	MBD1	MAP2	GATA3	GATA2	MYB	HDAC9	HSPD1	HSP90B1	HES1	VEGFA	SCN5A	MEF2C	HES5	HADHA	ACADM	GABRA1	POU5F1;POU5F1B	GNB3	ALDOA	RYR2	SST	SCN3B	MAZ	HIF1A	NANOG;NANOGP8	SCN4B	SP3	FMO3	IL1RN	GCK	TF	NGF	RORA	KCNQ1	THRB	TPPP	PRKACA-1	LMX1B	G6PC1	SNTA1	TP73	CAV3	NTRK2	FOXM1	AQP4	
EIF5A REGULATION IN RESPONSE TO INHIBITION OF THE NUCLEAR EXPORT SYSTEM%WIKIPATHWAYS_20260910%WP3302%HOMO SAPIENS	eIF5A regulation in response to inhibition of the nuclear export system	IGF2BP1	XPO1	XPO4	EIF5A;EIF5AL1	
ARACHIDONIC ACID AA ARA OXYLIPIN METABOLISM%WIKIPATHWAYS_20260910%WP5155%HOMO SAPIENS	Arachidonic acid AA ARA oxylipin metabolism	TBXAS1	PTGS1	PTGS2-2	EPHX2	
PROTEASOME DEGRADATION%WIKIPATHWAYS_20260910%WP183%HOMO SAPIENS	Proteasome degradation	UBE2D3-1	NEDD4	PSMD8	PSMD9	PSMD6	PSMD7	PSMD4	PSMD2	PSMD3	PSMD1	PSMC2-1	IFNG	PSMD5	UCHL3	PSME3	UBE2B	PSME1	PSME2	PSMD11	PSMD10	UBA7	RPN2	RPN1	PSMB10	PSMB9	UCHL1	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	UBE2D1	UBB;UBC	UBA1	H2AC4	H2AZ2;H2AZ1	PSMA5	PSMA6	PSMA3	PSMA4	PSMA1	UBE2D3;UBE2D2	PSMA7	PSMB6	PSMB7	PSMB4	PSMB5	PSMB2	PSMB3	PSMB1	PSMA2-1	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	PSMB8	PSMD12	PSMD13	
ARSENIC METABOLISM AND REACTIVE OXYGEN SPECIES GENERATION%WIKIPATHWAYS_20260910%WP5233%HOMO SAPIENS	Arsenic metabolism and reactive oxygen species generation	GSTO1	ATP1A1	COA3	SOD1	AS3MT	CAT	SDHA	UQCRFS1	VDAC1	
TRIACYLGLYCERIDE SYNTHESIS%WIKIPATHWAYS_20260910%WP325%HOMO SAPIENS	Triacylglyceride synthesis	PLPP2	LIPC	MOGAT3	AGPAT2	DGAT2	DGAT1	AGPAT4	PLPP1	GK	GNPAT	GPD1	AGPS	PNPLA2	MOGAT2	MOGAT1	AGPAT1	AGPAT3	GK2	LIPF	GPAM	LPL	AGPAT5-1	LIPE	PLPP3	
SHANK3 PATHWAY INVOLVED IN PHELAN MCDERMID SYNDROME%WIKIPATHWAYS_20260910%WP5566%HOMO SAPIENS	SHANK3 pathway involved in Phelan McDermid syndrome	ARHGAP44	SHARPIN	MAP3K7	LZTS3	GRIA1	BAIAP2	ABI1	CAMK2A	GRM5	GRIA2	GRM1	HRAS	CTTN	SYNGAP1	DLGAP1	DBNL	DLG4	ARHGEF7	HCN1	HOMER1	CDC42	PAK1	GRIN1	SHANK3	ACTB-1	RAP1A	ADGRL1	CTNND2	GRIN2B	ITGB1	ITPR1	TAB2	SPTAN1	
SERINE METABOLISM%WIKIPATHWAYS_20260910%WP4688%HOMO SAPIENS	Serine metabolism	SHMT1	SRR	PSAT1	PHGDH	SHMT2	TYMS	PSPH	DHFR2;DHFR	
MITOCHONDRIAL IMMUNE RESPONSE TO SARS COV 2%WIKIPATHWAYS_20260910%WP5038%HOMO SAPIENS	Mitochondrial immune response to SARS CoV 2	TRAF6	IRF3	NLRX1	TOMM70	MAVS	STING1	REN	TICAM1	CGAS	BCS1L	TRAF3	CTSV;CTSL	TMPRSS2	NDUFB9	ECSIT	TLR7	TLR3	PHB	PHB2	ACE2	ACE	ACAD9	AGTR1	AGTR2	IFIH1	TBK1	IRF7	NDUFAF1	IKBKE	NFKB1	NFKB2	DDX58	NOX1	
FLUOROACETIC ACID TOXICITY%WIKIPATHWAYS_20260910%WP4966%HOMO SAPIENS	Fluoroacetic acid toxicity	CS	ALDH2	ACO2	ALDH3A2	ACSS2	ALDH9A1	
POLYCYSTIC KIDNEY DISEASE PATHWAY%WIKIPATHWAYS_20260910%WP2571%HOMO SAPIENS	Polycystic kidney disease pathway	WNT11	MAPK3	PRKAA1	SLC12A2	GNA11	PLCG2	WNT7B	IKBKB	CTNNB1	FOS	RHEB	IGF1R	PRKAA2	PRKAG1	SFRP4	PRKAG2	EGF	VEGFB	PRKAG3	SRC	DVL1	ADCY6	DVL2	CCND1	MYC	PRKAB2	DVL3	STK11	PRKAB1	ERBB2	KCNN4	SSTR2	KDR	GNAI3	GNAI2	TNF	FZD10	IGF1	WNT5B	GNAI1	PKD2	CFTR	PDE1A	NRAS	HRAS	WNT6	WNT1	GNAS-1	WNT2	RPS6KA1	WNT4	GNAQ	WNT10B	WNT10A	KRAS	FZD2	JUN	FZD5	FZD4	FZD7	FZD6	FZD9	FZD8	FZD1	FZD3	WNT3A	WNT5A	TSC2	WNT7A	WNT2B	WNT3	PKD1	MTOR	TSC1	GSK3B	WNT9B	WNT9A	WNT16	BRAF	FLT1	MAP2K2;MAP2K1	WNT8A	WNT8B	
LTF DANGER SIGNAL RESPONSE PATHWAY%WIKIPATHWAYS_20260910%WP4478%HOMO SAPIENS	LTF danger signal response pathway	MYD88	TRAF6	TREM1	IL1B	AGER	IL1A	LTF	TLR2	CD14	TLR4	TNF	IFNB1-4	IL6	IRAK1	IRAK4	NFKB1	MAPK1	CXCL8	
FUMARATE HYDRATASE DEFICIENT PAPILLARY RENAL CELL CARCINOMA%WIKIPATHWAYS_20260910%WP4241%HOMO SAPIENS	Fumarate hydratase deficient papillary renal cell carcinoma	SLC2A1	CUL2	CREBBP	HIF1A	CADM2	COL21A1	ELOC-1	EP300	ELOB	CDKN1A	VHL	FH	TFE3	DVL2	PRCC	TGFA	BIRC7	DIAPH1	PDGFB	RBX1	TGFB2	VEGFA	SFPQ-1	TGFB1	TGFB3	ARNT	TFEB	EGLN1	SETD2	EGLN3	EPAS1	CTSK	EGLN2	
HEME BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP561%HOMO SAPIENS	Heme biosynthesis	UROS	PPOX	CPOX	HMBS	ALAD	ALAS2	ALAS1	FECH	UROD	
MAPK CASCADE%WIKIPATHWAYS_20260910%WP422%HOMO SAPIENS	MAPK cascade	MAPK3	LAMTOR3	MAP2K4	NRAS	MAP3K2	MAPK14	HRAS	MAPK12	ELK1	PLCB3	MAPK10	MAP3K12	RASA3	SIPA1	MAP2K7	RRAS	KRAS	MAP2K6	GRB2	MAP2K3	JUN	MAP3K1	SOS1	RAF1	ARAF	MAP2	MBP	SOS2	BRAF	MAP3K3	MAP2K2;MAP2K1	MAPK1	
EICOSANOID METABOLISM VIA LIPOOXYGENASES LOX %WIKIPATHWAYS_20260910%WP4721%HOMO SAPIENS	Eicosanoid metabolism via lipooxygenases LOX	HPGD	ALOX15	EHHADH-1	ALOX12	LTC4S	CYSLTR1	DPEP1	PTGR1-1	ALOX5	LTA4H	CYSLTR2	ACAA1-1	PTGR2	ACOX1	ACOX3	ALOX15B	PPARD	CYP4F3;CYP4F2;CYP4F12;CYP4F11	ACOX2	GGT5	TRPA1	LTB4R2	TRPV1	FPR2	LTB4R	PPARA	
G PROTEIN SIGNALING%WIKIPATHWAYS_20260910%WP35%HOMO SAPIENS	G protein signaling	AKAP8	GNG10	ADCY8	GNG13	GNA11	PRKCD	GNGT1	RRAS	ADCY4	ADCY2	PRKACB-1	ADCY7	ADCY6	PRKAR2B	PRKAR2A	PDE4B	ADCY5	PDE4A	PDE4D-1	PRKAR1B	PRKAR1A	GNAI3	GNAI2	ADCY9	GNB5	GNA13	GNA12	GNAO1	ARHGEF1	PDE1B	ADCY1	PRKCG	PRKCI	PRKCH	CALM1	PRKCB	GNB2	PRKCE	PRKCA	GNB1	ADCY3	GNB3	PRKCQ	PPP3CA	PRKD1	GNAI1	PPP3CC	PDE1A	NRAS	HRAS	PRKCZ	PLCB3	AKAP9-1	PDE7A	RHOA	GNAS-1	GNAQ	AKAP12	AKAP10	AKAP11	KRAS	PDE8B	SLC9A1	PDE8A	PDE4C	AKAP5	PDE1C	AKAP7	AKAP6	AKAP4	AKAP3	GNAZ	AKAP1	GNA14	AKAP13	GNA15	GNG5	KCNJ3	GNAL	GNG4	PDE7B	PRKACA-1	GNG8	PRKD3	ITPR1	
INTERFERON TYPE I SIGNALING%WIKIPATHWAYS_20260910%WP585%HOMO SAPIENS	Interferon type I signaling	RACK1	EIF4EBP1	JAK1	STAT1	MAPK14	STAT3	PTPN11	TYK2	VAV1	GAB2	PDCD4	RAPGEF1	RPS6KB1	CBL	PTPRC	CRK	STAT5A	PTPN6	CREB1	MAPKAP1	RPS6KA5	PRMT1	EIF4A1	IRS1	EIF4E	IRS2	MAP2K6	MAP2K3	MAP3K1	CRKL	STAT4	LCK	RPTOR	IFNAR2	EIF4B	STAT2	MLST8	FYN	PIK3CD	PIAS1	IRF9	MTOR	RPS6KA4	IFNAR1	RAP1A	SOCS1	REL	PIAS3	RPS6	PIK3R2	PIK3R1	ZAP70	SOCS3	RAC1	
BIOMARKERS FOR PYRIMIDINE METABOLISM DISORDERS%WIKIPATHWAYS_20260910%WP4584%HOMO SAPIENS	Biomarkers for pyrimidine metabolism disorders	DPYS	PUS1	CKB	UPB1	TYMP	TYMS	NT5C	NT5C3A	RRM2B	TK2	RRM1	UMPS	DHODH	DPYD	RRM2-1	
COVID 19 ADVERSE OUTCOME PATHWAY%WIKIPATHWAYS_20260910%WP4891%HOMO SAPIENS	COVID 19 adverse outcome pathway	CXCL10	TMPRSS2	IL2RA	IL2	IL1B	CSF3	TNF	AGT	CCL13;CCL2	ACE2	IL7	IL6	CCL3L1;CCL3L3;CCL3;CCL18	IL10	CXCL8	
PHOTODYNAMIC THERAPY INDUCED HIF 1 SURVIVAL SIGNALING%WIKIPATHWAYS_20260910%WP3614%HOMO SAPIENS	Photodynamic therapy induced HIF 1 survival signaling	SLC2A1	LDHA	PKM	SERPINE1	PGK1	HIF1A	HK1	BAX	SLC16A1	BCL2A1	EDN1	PTGS2-2	BCL2L1	EPO	TGFA	PFKL	NOS2	PDHA1	BIRC5	HIF1AN	BNIP3L	BNIP3	IGFBP2	TP53	IGFBP1	ANGPT2	ANGPT1	IGFBP3	PMAIP1	VEGFA	BAK1	BID	MCL1	TGFB3	ARNT	EGLN1	
PERTURBED THYROID HORMONE HOMEOSTASIS LEADING TO DEVELOPMENTAL NEUROTOXICITY%WIKIPATHWAYS_20260910%WP5517%HOMO SAPIENS	Perturbed thyroid hormone homeostasis leading to developmental neurotoxicity	SLCO4A1	SLCO1A2	SLCO3A1	SLC7A5	SLCO1C1	SLC7A8	SLC16A2	SLC16A10	
MAMMALIAN DISORDER OF SEXUAL DEVELOPMENT%WIKIPATHWAYS_20260910%WP4842%HOMO SAPIENS	Mammalian disorder of sexual development	PBX1	WT1	PTGDS	DMRT1	DHH	GATA4	MAPK11	FOXL2	CTNNB1	NR5A1	SRY	WNT4	AMH	INSL3	FGFR2	RSPO1	FST	EMX2	SRD5A1	SOX8	SOX9	RBFOX2	CBX2	FGF9	AMHR2	
MAPK SIGNALING%WIKIPATHWAYS_20260910%WP382%HOMO SAPIENS	MAPK signaling	HSPA6	RASGRF2	DUSP16	PPM1A	PPM1B	PTPN7	ATF2	ELK1	IKBKB	FGF21	CHUK	FOS	RELA	FLNA	CACNA2D1	EGF	CACNA2D3	CACNA2D2	PRKACB-1	CACNA2D4	CACNB1	MYC	CACNB2	HSPA8	CACNB3	CACNB4	CACNG6	CACNG7	PDGFB	CACNG8	RPS6KA5	PDGFRB	CACNG1	FGF2	CACNG2	TNF	CACNG3	ATF4	CACNG4	CACNG5	PPP3R1	LRRK2	MKNK1	MKNK2	MAP3K8	TAB2	TAB1	MAP3K14	RASA1	IL1B	FLNB	PPP3CA	FLNC	PPP3CB	CACNA1B	PPP3CC	CACNA1A	MAPK8	DUSP4	PLA2G4A	DUSP2	RPS6KA3	MAPT	TNFRSF1A	MAP2K7	MAP3K4	MAP2K6	MAP2K3	JUN	MAP3K1	TGFBR1-1	DDIT3	NR4A1	RAF1	MAP3K11	AKT2	AKT3	AKT1	MAP3K5	RPS6KA4	MAP3K6	NLK	MAP2K2;MAP2K1	CACNA1D	MAP3K13	MAPK1	RAC1	CACNA1C	MAP3K7	CACNA1F	MAPK3	MAP2K4	MAP3K2	PRKCD	CACNA1S	DUSP6	DUSP1	MAP3K12	IKBKG	RRAS	GRB2	TRAF2	SOS1	RASA2	FGF20	FGF23	FGF22	IL1A	FGF17	FGF16	FGF19	PLA2G4F	PLA2G4D	PLA2G4E	FGF1	GNA12	FGF3	FGF4	SOS2	FGF5	EGFR	FGF6	FGF7	FGF8	FGF9	PRKCG	FGF14	PRKCA	HSPA2	RASGRP1	FGF13	FGF12	FGF11	STK3	CD14	MAP4K3	MAP4K4	MAP4K1	MAP4K2	CACNA1H	NGF	TAOK2	ARAF	FGF18	FGFR4	NFATC1	FGFR3	FGFR2	DUSP10	FGF10	FGFR1	RRAS2	MRAS	RAP1B	RAP1A	MAP2K5	FASLG	NTRK2	BRAF	MAPK9	MAPK7	LAMTOR3	JMJD7-PLA2G4B;PLA2G4B	RAC3	MAPK14	MAPK12	MAPK13	MAPK10	MAPK11	NTF4	CDC25B	CRK	CACNA1I	JUND	CASP3	MAX	CDC42	PAK1	PAK2	RASGRP2	RASGRP4	RASGRP3	TP53	RELB	GADD45A	SRF	RASGRF1	ELK4	MAPKAPK2	FAS	BDNF	IL1R1	TGFB2	TGFB1	TGFB3	STK4	NFKB1	NFKB2	TGFBR2	TRAF6	NTRK1	ARRB1	ARRB2	PDGFA	IL1R2	MEF2C	NFATC3	NRAS	MAPK8IP2	HRAS	NF1	DUSP3	KRAS	CRKL	PTPN5	STMN1	PRKACA-1	NTF3	ECSIT	TAOK1	DAXX	HSPA1A;HSPA1B	HSPB1	MAPK8IP3	PPP5C	PTPRR	DUSP8	DUSP9	DUSP7	MAPKAPK3	RAPGEF2	MAPKAPK5	MAPK8IP1	HSPA1L	TAOK3	CACNA1E	CACNA1G	SMIM40	MAP3K20	
MELANOMA%WIKIPATHWAYS_20260910%WP4685%HOMO SAPIENS	Melanoma	MAPK3	STK19	GRM3	RHOB	PREX2	PDE5A	BAD	ERBB4	PTPN11	RB1	CDKN1A	RHOC	GRB2	CALML6	CALML3	SOS1	CALML4	MITF	SHC2	CCND1	PAK1	KDR	DDB2	EXOC7	PTEN	POLK	TP53	MDM2-2	GRIN2A	SOS2	E2F1	E2F2	KIT	E2F3	BAK1	GADD45B	GADD45A	CALM1	CALM2	GADD45G	CDK6	CDK4	NRAS	PIK3R3	BAX	HRAS	CTTN	NF1	RHOA	KRAS	RAF1	CDH1	CALM3;CALM1	ARAF	PIK3CD	AKT2	AKT3	VCL	PIK3CB	AKT1	CDKN2A	PIK3R2	BRAF	PIK3CA	PIK3R1	MAP2K2;MAP2K1	MAPK1	RAC1	
FARNESOID X RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2879%HOMO SAPIENS	Farnesoid X receptor pathway	CYP7A1	RXRA	FGF19	SLCO2B1	IP6K3	PPARGC1A	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	SLC10A1	ABCB4	CYP8B1	FKBP5	NR1H4	IRS2	BAAT	ABCB11	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	SULT2A1-4	NR0B2	SLC27A5	
THERMOGENESIS%WIKIPATHWAYS_20260910%WP4321%HOMO SAPIENS	Thermogenesis	SMARCD1	KDM3B	NPR1	SMARCD2	SMARCD3	UCP1	ADCY8	PRKAA1	SMARCC1	SMARCC2	PRDM16	ACTL6A	MAPK14	ATF2	BMP8A;BMP8B	PPARGC1A	ARID1B	MAPK12	SLC25A29	MAPK13	FGF21	CPT1A	MAPK11	ACTG1	RHEB	PNPLA2	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PRKACB-1	LIPE	PRKAB2	PRKAB1	CREB1	ARID1A	ACTB-1	ADCY1	BMP8B	KDM3A	RPS6KA3	RPS6KA2	RPS6KA1	MAP2K3	ACSL3	CPT1B	CPT2	CREB3L2	CPT1C	SMARCA2	TSC2	DPF1	SMARCA4	DPF3	MAP3K5	MTOR	RPS6	ACSL6	ACSL5	PRKG1	SMARCB1	SMARCE1	RPS6KB1	CREB3L3	GRB2	CREB3L4	CREB3L1	SOS1	ADCY4	ADCY2	ADCY7	ADCY6	GCG	ADCY5	ADCY10	ADCY9	SOS2	ACSL4	SLC25A20	RPS6KB2	ADCY3	NRAS	HRAS	GNAS-1	KRAS	CREB5	CNR1	KLB	KDM1A	RPTOR	PRKACA-1	RPS6KA6	ACSL1	FGFR1	MLST8	PRKG2	ACTL6B	TSC1	FRS2	SIRT6	CREB3	ADRB3	PPARG	AKT1S1	ZNF516	PLIN1	MGLL	
22Q11 2 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP4657%HOMO SAPIENS	22q11 2 copy number variation syndrome	ASF1A	FOXC2	FOXC1	GP1BA	TSKS	PITX2	EMC10	ZDHHC8	ZNF274;ZNF74	RCC1	GSC2	TANGO2	C22orf39	CLDN5	CLDN3	THAP7	TSSK2	RTL10	NPRL2	NPRL3	TRMT2A	ESS2	CBX5	KLHL22	PI4KA	SLC25A1	CDC42	GP5	GP9	LZTR1	LRRC74B	AIFM3	MRPL40	PAK4	TNPO1	PLK1	SCARF2	SNAP29	DGCR2	SEPTIN11-1	GP1BB	RANGAP1	SLC7A4	GNB1L	TP53	SHH	DEPDC5	SERPIND1	CCDC188	NCOR1	ARVCF	PAX3	LOC102724770;DGCR6;DGCR6L	RANBP1	SEPTIN8	ACTA2	RBX1	ALDH1A2	ARNTL	SEPTIN5	SRF	MAG	POLR2A	CLTCL1	PPP1CB	SREBF1	BCL2	RAF1	FOXA2	MED15	ALDH4A1	COMT	PRODH;LOC102724788	SREBF2	KPNB1	GBX2	DRD2	DROSHA	DGCR8	HDAC3	RTN4	CDH15	CYP26A1	RTN4R	RAN	RELN	CYP26B1	MALT1	UFD1	TBX1	CDC45	XPO1	PRKN	EGFR	FGF8	HES1	TXNRD2	NKX2-5	ACTC1;ACTG2	HAND2	CHRD	HIRA	VWF	HIRIP3	CUL3	GLUD1;GLUD2	RORC	CLDN1	CRKL	SLC2A4	FGFR2	FGF10	FGFR1	P2RX6	OAT	SHOC2	H4C1	
AFLATOXIN B1 METABOLISM%WIKIPATHWAYS_20260910%WP699%HOMO SAPIENS	Aflatoxin B1 metabolism	CYP2A13;CYP2A6;CYP2A7-1	AKR7A2	GSTM1;GSTM2-1	AKR7A3	CYP1A2	EPHX1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
CYTOPLASMIC RIBOSOMAL PROTEINS%WIKIPATHWAYS_20260910%WP477%HOMO SAPIENS	Cytoplasmic ribosomal proteins	RPL13A-1	RPS29	RPS20	RPS21	RPS24	RPS23	RPL18A	UBA52	RPS6KB1	RPS15A	RPS3	RPS2	FAU	RPL4	RPLP1-2	RPL3	RPL32	RPL31	RPL34	RPLP0	RPL8	RPL9	RPL6	RPS4X	RPL30	RPL7A	RPS27A	RPS6KB2	RPL37A-1	RPL35	RPL36-1	RPL39	RPL15-1	RPL21	RPL23	RPL22	RPS3A	RPL24	RPL29	RPL28	RPL10;RPL10L-1	MRPL19	RPL14	RPL7	RPS6KA3	RPL13	RPS6KA2	RPL12-1	RPS6KA1	RPL18	RPL17	RPL19	RPL35A	RPL27	RPL23A	RPL3L	RPL26	RPS25	RPS27	RPL27A	RPL5-1	RPS15	RPS14	RPL11	RPS17	RPS16	RPLP2	RPS6KA6	RPS19	RPS18	RPL38	RPS11	RPS10	RPS13	RPS12	RPL10A	RPS9	RPS7	RPS8	RPS5	RPSA	RPS6	
CANCER IMMUNOTHERAPY BY PD 1 BLOCKADE%WIKIPATHWAYS_20260910%WP4585%HOMO SAPIENS	Cancer immunotherapy by PD 1 blockade	LCK	CD8A	CD8B;CD8B2	PDCD1	NFATC1	IFNG	STAT3	CD3G	PDCD1LG2	PTPN11	CD3E	CD274	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	NFATC2	CD3D	JUN	NFATC3	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	NFAT5	ZAP70	NFATC4	BATF	NFKB1	
MFAP5 EFFECT ON PERMEABILITY AND MOTILITY OF ENDOTHELIAL CELLS VIA CYTOSKELETON REARRANGEMENT%WIKIPATHWAYS_20260910%WP4560%HOMO SAPIENS	MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement	ITGB3	MYLK	PRKCQ	MAPK3	CREB1	ITGAV	PLCG1	VCL	PXN	TJP1	MFAP5	JUN	PTK2	ACTN1	ITPR1	LPP	MYL2	MAPK1	
EFFECT OF OMEGA 3 PUFA ON HUNTINGTON 39 S DISEASE PATHWAYS%WIKIPATHWAYS_20260910%WP5470%HOMO SAPIENS	Effect of omega 3 PUFA on Huntington 39 s disease pathways	MAPK9	PRKAA1	CKB	REST	PPARGC1A	ELK1	IKBKB	MAPK10	RHEB	PRKAA2	AHI1	PRKAG1	PRKAG2	EGF	PRKAG3	CASP3	PRKAB2	PRKAB1	CREB1	RAB3A	RPS6KA5	MBP	RICTOR	BID	IL1B	HDAC2	MAPK8	CASP8	BAX	HMGCS1-1	MAP2K7	EIF4E	BDNF	NR1H2	BCL2	ABCG4	ABCG1	MAP3K10	SLC12A5	RAF1	HMGCS2	RAB3GAP1	CYP46A1	NEUROD1	SREBF2	TSC2	HAP1	AKT2	KIF5A	AKT3	AKT1	MTOR	SIN3A	HDAC1	PIK3R2	PIK3R1	ITPR1	NFKB1	MAP2K2;MAP2K1	MAPK1	EIF4EBP1	MAPK3	MAP2K4	SLC12A2	BAD	DHCR7	IL6	RPS6KB1	PRR5L	BCL2L1	APOE	OPA1	ABCA1	SP1	PTEN	BNIP3	HTT	EGFR	GABRB3	CASP7	GABRB2	GABRB1	GABRG3;GABRG2	GABRE	GABRD	GABRQ	GABRA2	GABRA1	GABRP	DEPTOR	GABRA6	GABRA5	GABRA4	GABRA3	GABRG1	PIK3R4	CYP51A1	PIK3R3	GRM1	HRAS	PIK3R6	PIK3R5	RPTOR	MLST8	BCL2L11	PIK3CD	PIK3C2G	PIK3CB	PIK3C2A	PIK3CG	HMGCR	TSC1	PIK3C2B	NTRK2	PIK3CA	AKT1S1	
MAP3K1 ROLE IN PROMOTING AND BLOCKING GONADAL DETERMINATION%WIKIPATHWAYS_20260910%WP4872%HOMO SAPIENS	MAP3K1 role in promoting and blocking gonadal determination	FGFR2	MAPK11	FOXL2	CTNNB1	AXIN1	RHOA	SRY	SOX9	WNT4	GSK3B	MAP3K4	FGF9	MAP3K1	ROCK1	MAPK1	GADD45G	
SEROTONIN RECEPTOR 4 6 7 AND NR3C SIGNALING%WIKIPATHWAYS_20260910%WP734%HOMO SAPIENS	Serotonin receptor 4 6 7 and NR3C signaling	HTR4	HTR6	ELK4	ATF1	MAPKAPK2	MAPK3	CREB1	HTR7	RPS6KA5	ELK1	GNAS-1	RAP1A	BRAF	NR3C1	EGR1	MAP2K2;MAP2K1	MAPK1	SRF	
TCA CYCLE AND DEFICIENCY OF PYRUVATE DEHYDROGENASE COMPLEX PDHC %WIKIPATHWAYS_20260910%WP2453%HOMO SAPIENS	TCA cycle and deficiency of pyruvate dehydrogenase complex PDHc	DLST	PC	OGDH	ACO1	PDHA1	ACLY	SUCLG2	IDH3A	CS	MDH1	DLAT	IDH1	DLD	SDHA	FH	PCK1	
FOCAL ADHESION%WIKIPATHWAYS_20260910%WP306%HOMO SAPIENS	Focal adhesion	ELK1	ACTG1	FLNA	ACTN1	EGF	FN1	ACTN4	TNC	CCND1	ERBB2	KDR	PDGFB	PDGFRB	ACTB-1	IGF1	FLNB	FLNC	MAPK8	JUN	BCL2	RAF1	MYL5	MYL7	TLN2	TXK	TNK2	MYL12A	TNK1	MYL10	SRMS	PTK6	PARVB	MYLPF	AKT2	PARVG	AKT3	ARHGAP5	AKT1	MYLK4	FGR	STYK1	GSK3B	PIK3R2	PIK3R1	MAP2K2;MAP2K1	MAPK1	RAC1	PDGFD	MAPK3	PDGFC	PPP1R12A	COL1A1	COL1A2	BAD	VAV1	HCK	IGF1R	TNXB	GRB2	SOS1	RELN	VEGFB	SHC4	SHC1-1	SHC2	VEGFD	IBSP	TNN	TNR	PDGFRA	COL4A2	COL4A1	PTEN	COL4A4	COL4A6	EGFR	VTN	CHAD	PRKCG	COL5A3	PRKCB	COL5A2	PRKCA	LAMC3	LAMC2	PIK3R3	LAMC1	XIAP	VWF	COL6A2	LAMA5	LAMA2	LAMA1	LAMA4	LAMA3	THBS2	MYLK2	THBS4	BUB1B-PAK6;PAK6	THBS3	ITGA2B	CAPN2	LAMB3	LAMB2	LAMB1	TLN1	PIK3CD	VCL	SHC3	PIK3CB	PXN	RAP1B	RAP1A	VASP	CAV3	CAV2	CAV1	BRAF	PTK2	PIK3CA	ITGA10	FLT1	ITGA11	ITGB1	PGF	ITGB5	ITGB4	ITGB3	ILK	MAPK9	RAC3	ITGB8	ITGAV	ITGB7	ITGB6	VAV3	ITGA4	PDPK1	MAPK10	ITGA3	CTNNB1	ITGA2	ITGA1	VAV2	ITGA8	RAPGEF1	ITGA7	ITGA6	ITGA5	CCND3	CRK	CCND2	DOCK1	ITGA9	ROCK1	ROCK2	SRC	CDC42	PAK1	PAK3	PAK2	PAK4	BIRC2	BIRC3	COMP	PPP1R12B	ZYX	BCAR1	EMP2	ARHGAP35	RASGRF1	PPP1CA	PPP1CB	PPP1CC	FYN	MYL12B	PIP5K1C	HGF	PDGFA	MYLK	SPP1	PPP1R12C	BLK	VEGFA	MYLK3	MYL2	HRAS	RHOA	TESK2	CRKL	MET	DIAPH1	PARVA	COL2A1	THBS1	VEGFC	
FAMILIAL HYPERLIPIDEMIA TYPE 3%WIKIPATHWAYS_20260910%WP5110%HOMO SAPIENS	Familial hyperlipidemia type 3	APOA4	VLDLR	LIPC	SCARB1	PLTP	APOA1	CETP	LRP1	APOA2	APOE	LPL	LDLR	LCAT	
CORTICOTROPIN RELEASING HORMONE SIGNALING%WIKIPATHWAYS_20260910%WP2355%HOMO SAPIENS	Corticotropin releasing hormone signaling	JUNB	MAPK9	MAPK3	CYP11A1	GNA11	PLCG2	PRKCD	MAPK14	ELK1	TFAP2A	CTNNB1	ARRB1	JUP	POMC	ARRB2	FOS	GJA1	RELA	CASP9	PRKAA2	JUND	NFKBIA	CASP3	CXCL8	IL18	FOSL1	STAR	IL2	GRK3	SP1	CREB1	GNAI2	TLR4	NCOA2	CRHR1	KRT16;KRT14	CRHR2	GNB5	GNAO1	RAPGEF3	CYP21A2	PRKCI	PRKCB	GNB2	PRKCA	GNB1	TCF4	GNB3	PRKCQ	GNAI1	MAPK8	CAMK2A	PLCG1	PARP1	HSP90AA1	RHOA	GNAS-1	CACNA1H	GNAQ	ACACA	NR4A2	CYP11B1;CYP11B2	BCL2	NR4A1	GNAZ	RAF1	TRIM28	HSD3B1;HSD3B2	NOS3	AKT1	MAP3K5	RAP1B	CRHBP	KRT1	ERN1	IVL	GRK6	GSK3B	TBX19	FOSL2	BRAF	FOSB	ECE1	SULT2A1-4	PTK2	TGFB1	MAP2K2;MAP2K1	NFKB1	MAPK1	CRH	
UDP DERIVED SUGARS SYNTHESIS IN FIBROBLASTS%WIKIPATHWAYS_20260910%WP5394%HOMO SAPIENS	UDP derived sugars synthesis in fibroblasts	GFPT1	GCK	HK2	UGDH	GALE	UXS1	PGM1	HK1	HK3	GPI	PGM3	
CHOLESTEROL METABOLISM%WIKIPATHWAYS_20260910%WP5304%HOMO SAPIENS	Cholesterol metabolism	APOA4	LIPC	APOC2	SCARB1	ANGPTL8	APOH	ANGPTL3	PLTP	EBP	NSDHL	SC5D	DHCR24	DHCR7	LBR	APOA1	ABCB11	APOE	LDLR	ABCA1	STAR	LIPA	STARD3	VDAC1	OSBPL5	APOC1	SORT1	CYP7A1	CD36	IDI1	CYP51A1	MVK	MSMO1	HSD17B7	ACAT2	TM7SF2	HMGCS1-1	PMVK	PCSK9	LIPG	FDFT1	LDLRAP1	MYLIP	MTTP	FDPS	LSS	SAR1B	TSPO	NPC1L1	MGAT1	APOB	ABCG8	ABCG5	FABP2	SQLE	SOAT1	APOC3	SLC27A4	DGAT1	NPC2	MVD	HMGCR	CYP27A1	CETP	NPC1-1	LRP1	LRPAP1	APOA2	CIDEB	LPL	VAPA	LCAT	
PRE IMPLANTATION EMBRYO%WIKIPATHWAYS_20260910%WP3527%HOMO SAPIENS	Pre implantation embryo	CELF3	NR3C2	FOXQ1	MACROH2A2	KHSRP	ZAR1	KLF4	AQP9	DPPA3	PADI6	BARX2	CDX2	LEUTX	ZFP36	NLRP5	MTA3	DPRX-1	MOS	TPRX1;RAX2	ZSCAN4	TBX3	NKX2-1	EGR1	DLX2	IRX5	FOXD1	GATA3	SOX8	GATA2	MYBL1	ATP1A1	E2F5	TCF7L1	ZFP42	POU5F1;POU5F1B	PBX1	DNMT3L	NANOG;NANOGP8	ELAVL1	TEAD4	SOX11	HNRNPAB	SOX2	ESRRA	MXD1	DDIT3	CDH1	SMARCA4	TFAP2E;TFAP2B	IRF4	BATF3	ZFP36L2	SIX3	FOSB	NANOGNB	AQP3	
NAD METABOLISM IN ONCOGENE INDUCED SENESCENCE AND MITOCHONDRIAL DYSFUNCTION ASSOCIATED SENESCENCE%WIKIPATHWAYS_20260910%WP5046%HOMO SAPIENS	NAD metabolism in oncogene induced senescence and mitochondrial dysfunction associated senescence	GOT1-1	SLC2A1	SLC2A4	IL1B	PRKAA1	PARP1	ELAVL1	SIRT5	TP53	SIRT1	NMNAT2	MDH2	SIRT2	SIRT3	G6PD	MDH1	IL6	CCL27	NAMPT	GOT2-1	RELA	
HAIR FOLLICLE DEVELOPMENT ORGANOGENESIS STAGE 2 OF 3%WIKIPATHWAYS_20260910%WP2839%HOMO SAPIENS	Hair follicle development organogenesis stage 2 of 3	BMP4	RUNX2	SMO	FOXI3	GTPBP4	CTNNB1	GJB6	SNAI1	TP63	GLI1	LAMA5	CCND2	PTCH1	PDGFA	CCND1	CDH1	MYC	EDA	FZD1	WNT5A	FGFR2	PDGFRA	GLI2	SHH	FGF1	LEF1	INHBA	NCAM1	ITGB1	LRP5	NFKB1	EDAR	
INSULIN SIGNALING IN ADIPOCYTES NORMAL CONDITION %WIKIPATHWAYS_20260910%WP3634%HOMO SAPIENS	Insulin signaling in adipocytes normal condition	SLC2A4	MTOR	INSR	RPS6KB1	IRS1	TBC1D4	RPS6	AKT2	
COMPLEMENT SYSTEM IN NEURONAL DEVELOPMENT AND PLASTICITY%WIKIPATHWAYS_20260910%WP5090%HOMO SAPIENS	Complement system in neuronal development and plasticity	ITGB3	ITGB2	CFP	ITGAX	ITGAV	PROS1	CLU	MPP5	C8G	C3AR1	LOC110384692;C4A;C4B_2;C4B	C5AR2	CR2	CASP9	MASP2	MASP1	CASP3	CFB	CFD	C1QB	C1S	APAF1	C1R	CFI	C5AR1	C2	CX3CR1	C6	C7	C9	CD55	C8B	C8A	CR1L;CR1	MBP	CYCS-1	CFH-3	BID	PARD3	PARD6B	CASP8	FAS	BAX	MBL2-1	CX3CL1	MFGE8	ATP8B2	TGFB2	TGFB1	TGFB3	C3-1	C1QC	CAP1	PATJ	C4BPA	C4BPB	ATP8B1	FCN2;FCN1	ATP10A	ATP11C	SCRIB	ATP11A	TYRO3	LLGL2	MARK3	ATP8B3	DLGAP5	C5	PLSCR1	PLSCR3	PLSCR4	GAS6	CRB2	COLEC12	CRB1	COLEC10	PARD6G	SUSD4	IFNG	CD59	CSMD1	DEDD	DIABLO-1	MERTK	HTRA2	VTN	CASP7	BAK1	PRKCI	PRKCZ	XIAP	SERPING1	PARD6A	AXL	MARK2	MARK1	FASLG	COLEC11	CASP10	ITGAM	
MITOCHONDRIAL GENE EXPRESSION%WIKIPATHWAYS_20260910%WP391%HOMO SAPIENS	Mitochondrial gene expression	PPP3CA	SP1	CREB1	NRF1	GABPB1	MTERF3	TFB2M	CAMK4	PPARGC1A	MTERF1-1	TFB1M	PPRC1	TFAM-1	HCFC1	MYEF2	GABPA	POLRMT	ESRRA	PPARGC1B	
ONCOSTATIN M SIGNALING%WIKIPATHWAYS_20260910%WP2374%HOMO SAPIENS	Oncostatin M signaling	JAK2	JUNB	MAPK9	MAPK3	JAK1	STAT1	PRKCD	MAPK14	STAT3	PTPN11	TYK2	JAK3	CDKN1B	FOS	OSMR	RELA	GRB2	IL6ST	SOS1	STAT5B	EGR1	JUND	NFKBIA	SHC1-1	CASP3	CEBPB	OSM	SRC	CREB1	PTK2B	CASP7	RICTOR	VEGFA	PRKCH	PRKCB	PRKCE	PRKCA	CDK2	MAPK8	HIF1A	HRAS	IRS1	KRAS	RAF1	AKT1	PXN	MTOR	LIFR	PIAS3	RPS6	PIK3R1	SOCS3	MAP2K2;MAP2K1	NFKB1	MAPK1	
MITOCHONDRIAL BETA OXIDATION%WIKIPATHWAYS_20260910%WP5241%HOMO SAPIENS	Mitochondrial beta oxidation	EHHADH-1	ECHS1	DECR1	ACAA2	ECI1	ACSL3	HSD17B10	ACADSB	ACADL	
HALLMARK OF CANCER SUSTAINING PROLIFERATIVE SIGNALING%WIKIPATHWAYS_20260910%WP5475%HOMO SAPIENS	Hallmark of cancer sustaining proliferative signaling	JAK2	IL6R	MAPK3	NGFR	NTRK1	STAT3	ELK1	IKBKB	PPARD	CTNNB1	IKBKG	CHUK	RUNX1T1	CDKN1A	JUP	FOS	ZBTB16	IL6	RHEB	IGF1R	RELA	GRB2	SOS1	NFKBIA	SHC1-1	SRC	CCND1	MYC	INSR	KDR	PDGFRA	FLT4	ULK2	PDGFRB	PTEN	SALL4	TP53	MDM2-2	CSF1R	AXIN2	SOS2	LEF1	EGFR	KIT	CSNK1A1	PML	BCL9	APC	DEPTOR	TELO2	HRAS	WNT1	KRAS	TTI1	FOXO1-1	JUN	FZD6	RAF1	MET	NFKBIE	RPTOR	FGFR4	FGFR3	FGFR2	TSC2	FLT3	MLST8	FGFR1	LRP6	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	MTOR	PIK3CG	TSC1	RETN	TEK	KSR1	RARA	GAREM2	REL	GSK3B	NTRK2	BRAF	PIK3CA	PTK2	FLT1	AKT1S1	PYGO1	LRP5	MAP2K2;MAP2K1	NFKB1	EPHA2	MAPK1	
HEMOGLOBIN SWITCHING EMBRYONIC FETAL AND ADULT%WIKIPATHWAYS_20260910%WP5605%HOMO SAPIENS	Hemoglobin switching embryonic fetal and adult	HBZ	HBG2;HBG1	LDB1	HBA2;HBA1	TAL1	LMO2	GATA1	HBD;HBB	
GENES RELATED TO PRIMARY CILIUM DEVELOPMENT BASED ON CRISPR %WIKIPATHWAYS_20260910%WP4536%HOMO SAPIENS	Genes related to primary cilium development based on CRISPR	TCTN2	TCTN1	BBS9	BBS7	CEP97	CLUAP1	CC2D2A	BBS5	ARMC9	RPGRIP1L	TMEM216	CEP104	ARL3	ARL13B	MIB1	TMEM67	INPP5E	PIBF1	BBS2	BBS1	MKS1	CPLANE1	TMEM231	TTC8	TMEM17	KIF3A	B9D1	EVC2	TTC21B	EVC	KIAA0753	OFD1-1	CEP20	BBS4	IFT172	IFT74	CEP192	TRAF3IP1	IFT88	CEP19	TXNDC15	CDK20	TRAPPC11	KIFAP3	WDPCP	TEDC1	TEDC2	ARL6	FBF1	TTBK2	KIF3B	CEP76	CPLANE2	SASS6	CEP83	CIBAR1	TTC23	C2CD3	CBY1	EFCAB7	TMEM107	MKKS	CEP295	BBS10	BBS12	CILK1	TUBD1	TULP3	KATNB1	RAB23	SCLT1	TUBE1	RABL2A;RABL2B	CEP162	CEP44	DYNC2H1	DYNC2I2	CEP43	LZTFL1	DYNC2I1	TTC30A;TTC30B	DYNLT1	IFT140	DYNLT2B	WDR19	IFT122	IFT80	FUZ	WDR35	HSPB11	DYNC2LI1	IFT20	IFT43	IFT81	IFT27	TTC26	IFT46	IFT52	IFT57	CEP120	TCTN3	
ULCERATIVE COLITIS SIGNALING%WIKIPATHWAYS_20260910%WP5174%HOMO SAPIENS	Ulcerative colitis signaling	NFATC1	IL4	FOXP3	IFNG	MAF	TLR2	TNF	IL5	GATA3	IL2RG	STAT6	IL13	IL4R	TGFB1	NOD2	HLA-DMA	IL10	NFKB1	
RETINOBLASTOMA GENE IN CANCER%WIKIPATHWAYS_20260910%WP2446%HOMO SAPIENS	Retinoblastoma gene in cancer	POLE2	RPA3	RRM1	MAPK13	RB1	CDKN1A	SMC3	POLA1	CDKN1B	MCM7	RRM2-1	SKP2	CCND3	CDC25B	TFDP1	TFDP2	MCM3	MCM4	CHEK1	MCM6	CCND1	FAF1	MYC	PRIM1	HMGB2	SMC1A	CDC45	CDC25A	ORC1	HMGB1-1	TOP2A	CDC7	CCNE2	CCNE1	WEE1	TP53	MDM2-2	CCNA2-1	PRMT2	CCNB2	CCNB1	ANLN	ABL1	E2F1	E2F2	BARD1	CDT1	MSH6	TTK	E2F3	RPA2	CDK6	H2AZ2;H2AZ1	DNMT1	CDK4	CDK2	PRKDC	CDK1	TYMS	FANCG	DHFR2;DHFR	SMC2	KIF4B;KIF4A	DCK	NPAT	HLTF	POLE	PLK4	RABIF	RFC5	RBBP7	ZNF655	RFC3	CCDC6	RFC4	RAF1	STMN1	SMARCA2	SUV39H1	POLD3	SAP30	RBP1	PCNA	SIN3A	HDAC1	RPA1	RBBP4	
VITAMIN B12 DISORDERS%WIKIPATHWAYS_20260910%WP4271%HOMO SAPIENS	Vitamin B12 disorders	CBLIF	CD320	MMAB	MTRR	TCN2	TCN1	MTR-1	CUBN	MMUT	AMN	MMAA	MMACHC	MMADHC	
2Q13 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5222%HOMO SAPIENS	2q13 copy number variation syndrome	POLR1A	POLR1B	ARF6	POLR1D	CSF2	POLR1E	PLCG2	STAT1	IL6	LGALS3	GRB2	IL36A	IL36B	IL36G	ANAPC1	GAS6	IL1F10	IL2	IL1A	MERTK	CXCL13	GATA3	CSF1	IL1RAP	IL37	IL36RN	IL1B	IL1RL2	POLR1C	IL1RN	ZC3H8	ZC3H6	CHCHD5	ACOXL	POLR2L	PSD4	ARL14	CKAP2L	IL1R1	IL23A	POLR1F	POLR1G	POLR1H	FBLN7	TMEM87B	SLC20A1	BCL2L11	TULP1	TTL	SOCS1	POLR2E	POLR2F	POLR2H	PTK2	SOCS3	MAPK1	RAC1	
COPPER HOMEOSTASIS%WIKIPATHWAYS_20260910%WP3286%HOMO SAPIENS	Copper homeostasis	MT3	SLC31A1	MTF1	MT2A	BACE1	CCS	XIAP	MTF2	MAPT	SLC11A2	COX11	STEAP3	APP	FOXO1-1	JUN	ADAM9	CASP3	CCND1	STEAP4	SOD3	SOD1	SP1	PTEN	FOXO3	AKT1	TP53	MDM2-2	COX17	ATP7B	ATP7A	PRNP	SLC31A2	COMMD1	ADAM17	ATOX1	GSK3B	SCO1	STEAP1	STEAP2	PIK3CA	ADAM10	APC	
OMEGA 9 FATTY ACID SYNTHESIS%WIKIPATHWAYS_20260910%WP4724%HOMO SAPIENS	Omega 9 fatty acid synthesis	FADS2	ACSL1	SCD	FADS1	ELOVL2	ELOVL5	ACOT2;ACOT1	ELOVL1	ELOVL3	SCD5	ACSL3	ELOVL6	ACSL4	FASN	
SMC1 SMC3 ROLE IN DNA DAMAGE CORNELIA DE LANGE SYNDROME%WIKIPATHWAYS_20260910%WP5118%HOMO SAPIENS	SMC1 SMC3 role in DNA damage Cornelia de Lange Syndrome	RAD50	NBN	SMC3	MRE11	SMC1A	PAXIP1	RAD21	BRCA1	RAD18	ATM	MDC1	
INSULIN SIGNALING IN ADIPOCYTES DIABETIC CONDITION %WIKIPATHWAYS_20260910%WP3635%HOMO SAPIENS	Insulin signaling in adipocytes diabetic condition	SLC2A4	MTOR	INSR	RPS6KB1	IRS1	TBC1D4	RPS6	AKT2	
IL9 SIGNALING%WIKIPATHWAYS_20260910%WP22%HOMO SAPIENS	IL9 signaling	IL9	IL9R	MAPK3	JAK1	STAT1	STAT3	JAK3	IL2RG	GRB2	PIK3R2	PIK3R1	STAT5A	STAT5B	CDK9	MAP2K2;MAP2K1	MAPK1	
MITOCHONDRIAL COMPLEX IV ASSEMBLY%WIKIPATHWAYS_20260910%WP4922%HOMO SAPIENS	Mitochondrial complex IV assembly	COX18	HIGD1A	PET117	COX14	COX10	CMC1	TMEM177	PNKD	NDUFA4	SMIM20	COX20	COX6A1	COX11	COX6B1	COX7A2	COX7B	COX4I1	COX7C	COX8A	COX5B	COX5A	COX6C	COX17	COA3	SURF1	COX19	COX15	TACO1	
PTDINS 4 5 P2 IN CYTOKINESIS PATHWAY%WIKIPATHWAYS_20260910%WP5199%HOMO SAPIENS	PtdIns 4 5 P2 in cytokinesis pathway	MSN	RHOA	RACGAP1	EZR	ANLN	SEPTIN2	RAB35	RDX	AFAP1	MYL2	KIF23	OCRL	
TOLL LIKE RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP75%HOMO SAPIENS	Toll like receptor signaling	CXCL10	TRAF6	MAP3K7	IRF3	MAPK9	MAPK3	NFKBIB	MAP2K4	STAT1	MAPK14	MAPK12	IL12B	MAPK13	IKBKB	MAPK10	MAPK11	IKBKG	CHUK	LBP	FOS	IL6	RELA	CCL3L1;CCL3L3;CCL3;CCL18	NFKBIA	CXCL8	CCL4L2;CCL4L1;CCL4	TICAM2	SPP1	TIRAP	TLR1	TLR9	TLR8	TLR6	IL12A	TLR7	TLR4	TNF	TLR3	IFNB1-4	CXCL9	IRAK1	MAP3K8	IRF7	TOLLIP	TAB3	CXCL11	TAB2	TAB1	MYD88	IL1B	MAPK8	CASP8	LY96	CD14	RIPK1	FADD	TICAM1	MAP2K7	MAP2K6	MAP2K3	JUN	TRAF3	CD40	IFNAR2	TLR5	TLR2	CCL5	AKT2	AKT3	CD86	AKT1	CD80	IFNAR1	IRF5	TBK1	IRAK4	IKBKE	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	
OSTEOARTHRITIC CHONDROCYTE HYPERTROPHY%WIKIPATHWAYS_20260910%WP5373%HOMO SAPIENS	Osteoarthritic chondrocyte hypertrophy	JAK2	JUNB	MAPK3	COL1A1	NTRK1	STAT3	CCN2	GANC	DDR2	CNMD	P4HTM	FOS	LAMTOR1	RELA	ACAN	JUND	CEBPB	VHL	FOSL1	COL3A1	FGF23	IBSP	SPP1	KDR	SOX9	RELB	VEGFA	PRKCA	RUNX2	COL10A1	HIF1A	NGF	JUN	FGFR4	MMP13	FGFR3	FGFR2	FGFR1	AKT2	COL2A1	AKT3	AKT1	FOSL2	FOSB	PIK3CA	ARNT	NFKB1	MAPK1	EPAS1	
GANGLIO SERIES SPHINGOLIPID METABOLISM%WIKIPATHWAYS_20260910%WP5299%HOMO SAPIENS	Ganglio series sphingolipid metabolism	ST8SIA1	HEXB	B3GALT4	ST3GAL4	ST8SIA5	ST3GAL1	ST3GAL2	HEXA	NEU3	ST8SIA6	NEU4	ST3GAL5	B4GALNT1	
BEMPEDOIC ACID THERAPY IN ATHEROSCLEROSIS AND METABOLIC SYNDROME%WIKIPATHWAYS_20260910%WP5500%HOMO SAPIENS	Bempedoic acid therapy in atherosclerosis and metabolic syndrome	MAPK9	MAPK3	PRKAA1	MAPK8	MAPK14	MAPK12	MAPK13	MAPK10	MAPK11	G6PC2	G6PC3	PRKAA2	ACACA	PRKAG1	PRKAG2	ACACB	PRKAG3	PRKAB2	PRKAB1	ACLY	PCK2	G6PC1	CRP	SLC27A2	MAPK1	
AGE RAGE PATHWAY%WIKIPATHWAYS_20260910%WP2324%HOMO SAPIENS	AGE RAGE pathway	JAK2	MAPK9	AGER	MAPK3	ALPL	STAT1	PRKCD	MAPK14	ATF2	STAT3	INHBB	IKBKB	CHUK	LGALS3	MMP2	DDOST	RELA	CASP9	MSR1	MMP9	STAT5A	STAT5B	NFKBIA	SHC1-1	CASP3	ROCK1	FOXO4	SRC	CDC42	MSN	NOS2	INSR	TIRAP	SOD1	SP1	NCF1	CYCS-1	EGFR	PRKCB	PRKCA	MYD88	EZR	MAPK8	HIF1A	CASP8	PRKCZ	PLA2G4A	RHOA	IRS1	FOXO1-1	JUN	INS;INS-IGF2	MMP7	RAF1	SMAD2;SMAD3	MMP14	MMP13	DIAPH1	NOS3	AKT1	IRAK4	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	
ARYL HYDROCARBON RECEPTOR RESPONSE TO MAIN MEDIATORS PAH AND TCDD%WIKIPATHWAYS_20260910%WP2586%HOMO SAPIENS	Aryl hydrocarbon receptor response to main mediators PAH and TCDD	AHRR	CDK2	NRAS	NCOR2	CD36	HRAS	FGF21	HSP90AA1	CYP1A2	RET	EP300	NF1	RB1	CDKN1A	CDKN1B	CYP1A1	KRAS	RELA	PTGS2-2	PLAGL1	HPGDS	AIP	KLF6	PSRC1	NCOA7	ESR1	GCLC	SRC	RAF1	MYC	NRIP1	NQO1	CCL1	TNF	CDC37	NFE2L2	CYP1B1	AHR	EGFR	E2F1	VEGFA	ARNT	MAP2K2;MAP2K1	NFKB1	LPL	MAPK1	
HALLMARK OF CANCER METASTASIS AND EPITHELIAL TO MESENCHYMAL TRANSITION%WIKIPATHWAYS_20260910%WP5469%HOMO SAPIENS	Hallmark of cancer metastasis and epithelial to mesenchymal transition	TCF4	CDH1	SIX1	HDAC2	SUV39H1	ELF3	FOXC2	ZEB1	EZH2	SIRT1	ZEB2	GSC2	SNAI1	SNAI2	GRHL2	PRRX1	HDAC1	TGFB1	KDM1A	KLF8	SUZ12	ELF5	
THYROID STIMULATING HORMONE TSH SIGNALING%WIKIPATHWAYS_20260910%WP2032%HOMO SAPIENS	Thyroid stimulating hormone TSH signaling	JAK2	MAPK3	JAK1	MYL12B	APEX1	STAT1	MAPK14	STAT3	PDPK1	RB1	TSHR	CDKN1B	IGF1R	RPS6KB1	SCRIB	CCND3	PLD1	ADCY2	CGA	SRC	KCNIP3	PDE4D-1	CREB1	GNAI3	RALGDS	GNAI2	CCNE1	GNA13	GNA12	GNAO1	GNB1	ADCY3	GNAI1	CDK4	CDK2	HRAS	RAP1GAP	GNAS-1	RPS6KA1	GNAQ	PLCB1	MAP2K6	MAP2K3	RAF1	GNG2	RBL2	TSHB	AKT1	MTOR	RAP1B	RAP1A	RPS6	PIK3R2	BRAF	PIK3CA	PIK3R1	MAP2K2;MAP2K1	MAPK1	
ERYTHROPOIESIS%WIKIPATHWAYS_20260910%WP5607%HOMO SAPIENS	Erythropoiesis	EPO	KITLG	CD79A	HBA2;HBA1	FAS	EPOR	GDF11	GATA2	HBZ	TFRC	IL3	FASLG	TF	HBG2;HBG1	PTPRC	IL3RA	CD34	KIT	GATA1	HBD;HBB	
PGK1 PKM2 KHKC KHKA ACTING AS PROTEIN KINASES%WIKIPATHWAYS_20260910%WP5433%HOMO SAPIENS	PGK1 PKM2 KHKC KHKA acting as protein kinases	KHK	H3-3A	SNAP23	PAK2	PKM	PGK1	PRPS1	PDK1	STAT3	BUB3	AKT1S1	BECN1	MYL2	
PRIMARY OVARIAN INSUFFICIENCY%WIKIPATHWAYS_20260910%WP5461%HOMO SAPIENS	Primary ovarian insufficiency	COX10	PPM1B	ATG9A	PCCA	PCCB	POLG	RFWD3-2	ESR1	PRORP	RCBTB1	NBN	STAR	MEIOSIN	POF1B	MEIOB	SIL1	SOHLH2;CCDC169-SOHLH2	HFM1	NANOS3	BMP15-1	LARS2	SGO2	PREPL	NOBOX	KHDRBS1	AARS2	SOX8	AIRE	SYCP2L	MST1R	HMMR	WDR62	LIG4	BLM	SYCE1	ANTXR1-1	SOHLH1	ZP3;POMZP3	KASH5	AMHR2	SWI5	HELQ	ERAL1	HARS2	FIGLA	DAZL	CPEB1	GDF9	DIAPH2	STAG3	FSHR	MSH5	H1-8	HROB	DMC1	LHX8	FANCI	BNC1	RAD51	FANCM	MCMDC2	XRCC4	ELAVL2	FANCL	C1orf146	LMNA	FANCA	MRPS22	TWNK	WT1	FANCC	SPIDR	C14orf39	HAX1	LGR4	GALT	ATM	SLX4	SHOC1	CCDC185	MGME1	MND1	CENPE	XPNPEP2	SPATA33	EXO1	EIF2B2	WRN	NUP107	PRDM1	MLH1	EIF4ENIF1	CYP19A1	POLR2C	ZAR1	AR	POLR3H	ERCC6	PSMC3IP	FOXL2	NR5A1	AMH	TP63	DCAF17	NUP43	ESR2	MSH4	STRA8	CLPP	SALL4	BRCA2	XRCC2	HSD17B4	HSD17B1	ATG7	ALOX12	NOTCH2	CYP17A1	FMR1	LAMC1	GNAS-1	BMP6	EIF2B1	EIF2B5	EIF2B4	BMPR1B	BMPR1A	PMM2	BMPR2	TGFBR3	MCM8	MCM9	CAV1	PGRMC1	
REGULATION OF ACTIN CYTOSKELETON%WIKIPATHWAYS_20260910%WP51%HOMO SAPIENS	Regulation of actin cytoskeleton	RAC3	MAPK6	GIT1	MAPK4	WAS	RDX	FGF21	ITGA1	ACTG1	ARHGEF7	CRK	ACTN1	DOCK1	EGF	FN1	ROCK1	ROCK2	CDC42	PAK1	CSK	PAK3	PAK2	PAK4	PDGFB	PDGFRB	FGF2	BCAR1	ACTB-1	ARHGAP35	CHRM1	PIP4K2A	WASF1-1	NCKAP1	MYH10	SLC9A1	RASSF7	ARPC5	SSH2	SSH3	SSH1	VIL1	DIAPH3	PIP5KL1	ARHGEF4	RAF1	ARHGEF6	FGD1	WASF2	ABI2	PIK3R2	PIP4K2B	PIK3R1	PIP4K2C	MAP2K2;MAP2K1	MAPK1	RAC1	ENAH	MAPK3	PPP1R12A	PIP5K1A	PIP5K1B	PIP5K1C	MOS	VAV1	RRAS	F2	PFN1	SOS1	CHRM4	CHRM5	PDGFA	MSN	FGF20	CHRM2	MYLK	FGF23	FGF22	CFL1	FGF17	FGF16	PDGFRA	FGF19	F2R	APC2	GNA13	FGF1	GNA12	FGF3	ARHGEF1	FGF4	SOS2	FGF5	IQGAP1	FGF6	EGFR	FGF7	FGF8	FGF9	FGF14	CYFIP2	MYL1	APC	MYL3	EZR	FGF13	BAIAP2	FGF12	FGF11	NRAS	PIK3R4	PIK3R3	CD14	PIK3R5	GSN	RHOA	KRAS	BDKRB2	BUB1B-PAK6;PAK6	CFL2	FGF18	PAK5	FGFR4	FGFR3	LIMK1	FGFR2	DIAPH1	FGF10	FGFR1	PIK3CD	RRAS2	VCL	PIK3C2G	BDKRB1	MRAS	PIK3CB	PXN	PIK3C2A	CHRM3	PIK3CG	PIK3C2B	BRAF	PTK2	PIK3CA	PIK3C3	
MIRNAS INVOLVED IN DNA DAMAGE RESPONSE%WIKIPATHWAYS_20260910%WP1545%HOMO SAPIENS	miRNAs involved in DNA damage response	RAD52	CCND1	CDK6	MYC	CDC25A	CREB1	CCNE1	ATM	TP53	CDKN1A	CDKN1B	ABL1	E2F1	CCND3	
WHITE FAT CELL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP4149%HOMO SAPIENS	White fat cell differentiation	IRF3	NR1H3	KLF4	SREBF1	WNT10B	CEBPA	NR2F2	NR3C1	FOXO1-1	TLE3	RORA	INS;INS-IGF2	STAT5A	STAT5B	DDIT3	CEBPB	MECOM	CTNNA1	EBF1	CREB1	EGR2	CEBPD	GATA3	GATA2	KLF15	KLF2	KLF5	IRF4	ZNF423	RARA	PPARG	TCF7L1	
INTEGRATED CANCER PATHWAY%WIKIPATHWAYS_20260910%WP1971%HOMO SAPIENS	Integrated cancer pathway	RAD50	JAK1	POU2F1	CDK4	CDK2	CDK1	STAT1	CASP8	BAD	BAX	ATM	BACH1	ATR	MMP1	RB1	CDKN1A	CDKN1B	MRE11	BRCA1	BBC3	CASP9	CDC25B	CHEK2	CASP3	BCL2	CHEK1	SMAD2;SMAD3	MYC	ATF1	CDC25A	PLK1	PTEN	CDKN2B	AKT1	TP53	MDM2-2	MAP3K5	BLM	E2F1	BARD1	NOXA1	MSH6	MSH2	
EXTRACELLULAR VESICLE MEDIATED SIGNALING IN RECIPIENT CELLS%WIKIPATHWAYS_20260910%WP2870%HOMO SAPIENS	Extracellular vesicle mediated signaling in recipient cells	NRAS	HRAS	CTNNB1	HGF	KRAS	SMAD4	TGFBR1-1	SMAD2;SMAD3	RAF1	MET	TGFA	ERBB2	PROM1	WNT3A	WNT5A	DKK4	AKT1	TGFBR3	MTOR	AXIN1	MFGE8	EGFR	TGFB2	TGFB1	TSPAN8	TGFB3	TGFBR2	APC	
PYRIMIDINE METABOLISM AND RELATED DISEASES%WIKIPATHWAYS_20260910%WP4225%HOMO SAPIENS	Pyrimidine metabolism and related diseases	CPS1	GLS2	DPYS	CAD	UPB1	OTC	TYMP	ABAT	TYMS	NT5C	AGXT2	NT5C3A	RRM2B	TK2	RRM1	UMPS	DHODH	ALDH6A1	DPYD	RRM2-1	
PPAR ALPHA PATHWAY%WIKIPATHWAYS_20260910%WP2878%HOMO SAPIENS	PPAR alpha pathway	ACADM	APOA5	CCND1	APOC3	MYC	EHHADH-1	NR1H3	FABP1	CYP7A1	CDK4	KLK15	RXRA	CDK1	PLTP	SCP2	ACAA1-1	CPT1A	CYP8B1	PPARA	APOA1	SLC27A1	APOA2	CPT2	
GLP 1 SECRETION FROM INTESTINE TO PORTAL VEIN%WIKIPATHWAYS_20260910%WP5446%HOMO SAPIENS	GLP 1 secretion from intestine to portal vein	GCG	GNAQ	PCSK1	SLC2A2	SLC5A1-1	
MIRNA BIOGENESIS%WIKIPATHWAYS_20260910%WP2338%HOMO SAPIENS	miRNA biogenesis	DICER1	TARBP2	RAN	XPO5	DROSHA	DGCR8	
BLADDER CANCER%WIKIPATHWAYS_20260910%WP2828%HOMO SAPIENS	Bladder cancer	CDK4	NRAS	HBEGF	HRAS	MMP1	RB1	CDKN1A	MMP2	KRAS	MMP9	DAPK2	EGF	DAPK3	CXCL8	SRC	RAF1	CCND1	CDH1	ARAF	MYC	ERBB2	FGFR3	TYMP	UPK3A	RPS6KA5	TP53	MDM2-2	THBS1	DAPK1-1	EGFR	E2F1	CDKN2A	PIK3R2	BRAF	VEGFA	PIK3R1	RASSF1	MAP2K2;MAP2K1	MAPK1	
CYTOSOLIC DNA SENSING PATHWAY%WIKIPATHWAYS_20260910%WP4655%HOMO SAPIENS	Cytosolic DNA sensing pathway	CXCL10	POLR3B	RNF125	IRF3	POLR3D	POLR3E	NFKBIB	POLR1D	NLRX1	CYLD	MAVS	POLR3H	TREX1	STING1	POLR3K	IKBKB	ISG15	IKBKG	CHUK	CGAS	IL6	RELA	NFKBIA	IL18	CCL4L2;CCL4L1;CCL4	IL33	IFNB1-4	PYCARD	CASP1	IRF7	ATG12-1	ATG5	IL1B	CASP8	RIPK3	TRADD	RIPK1	FADD	POLR1C	POLR2L	ZBP1	CCL5	POLR3GL	POLR3A	ADAR	POLR3C	POLR3F	POLR3G	AIM2	POLR2E	POLR2F	TBK1	CASP10	POLR2H	TRIM25	IKBKE	NFKB1	DDX58	
AGE RELATED MACULAR DEGENERATION%WIKIPATHWAYS_20260910%WP5526%HOMO SAPIENS	Age related macular degeneration	PRKAB2	RPTOR	PRKAB1	MAPK3	PRKAA1	MLST8	PPARGC1A	SIRT1	MTOR	MDH1	RPS6KB1	PMAIP1	PRKAA2	PRKAG1	PRKAG2	PRKAG3	PARP2	
PROSTAGLANDIN SYNTHESIS AND REGULATION%WIKIPATHWAYS_20260910%WP98%HOMO SAPIENS	Prostaglandin synthesis and regulation	PTGFR	PTGER3	HPGD	PTGS1	TBXA2R	CYP11A1	PTGDR	PTGIR	PTGDS	CBR1-1	PPARGC1A	PTGIS	PLA2G4A	EDN1	ANXA2	ABCC4	ANXA1	TBXAS1	PTGS2-2	AKR1B1	HPGDS	MITF	PPARGC1B	HSD11B1	HSD11B2	ANXA5	ANXA8;ANXA8L1	PTGER4	ANXA6	PTGFRN	SOX9	S100A10	PTGER2	PRL	ANXA3	ANXA4	SCGB1A1	S100A6	EDNRA	PPARG	EDNRB	PTGES	PTGER1	
P53 TRANSCRIPTIONAL GENE NETWORK%WIKIPATHWAYS_20260910%WP4963%HOMO SAPIENS	p53 transcriptional gene network	RPRM	ULBP3;ULBP1;RAET1G;ULBP2;RAET1L	SIVA1	PRKAA1	SERPINE1	ICAM1	ISG15	BTG2	SAT1	TIGAR	CDKN1A	SLC7A11	BBC3	PRKAA2	PIDD1	PRKAG1	PRKAG2	PRKAG3	SESN1	PRKAB2	APAF1	TRAF4	PRKAB1	FUCA1	TP53I3	CDC25C	CDC25A	DDB2	ULK2	RRM2B	ULK1	PTEN	TNF	CCNE1	POLK	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	SESN2	TP53INP1	PMAIP1	SFN	LIF	MSH2	GADD45A	PML	XPC	SLC2A1	DEPTOR	GLS2	CDK2	NOTCH1	CCNG1	FANCC	FAS	NANOG;NANOGP8	BAX	GPX1	NCF2	CX3CL1	POLH	ERCC5;BIVM-ERCC5	ALDH4A1	RPTOR	CPT1C	TSC2	MLST8	IRF9	MTOR	CCL13;CCL2	FASLG	THBS1	ADORA2B	PCNA	IRF5	XRCC5	ACAD11	SERPINB5	MGMT	SCO2	ADGRB1	ULBP1-2	AURKA	AKT1S1	DDIT4	DRAM1	ZMAT3	MLH1	PERP	E2F7	
ETHER LIPID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP5275%HOMO SAPIENS	Ether lipid biosynthesis	PEDS1-UBE2V1;PEDS1	PEX19	LPCAT1	PEX1	PEX7	PEX16	ALDH3A2	PEX5L	LPIN3	DHRS7B	AGMO	DGKQ	FAR2	ACAD10	CEPT1	ARSA	UGT8	GNPAT	GAL3ST1	AGPS	LPIN1	LPIN2	FAR1	PEX3	
MIR 222 IN EXERCISE INDUCED CARDIAC GROWTH%WIKIPATHWAYS_20260910%WP3938%HOMO SAPIENS	miR 222 in exercise induced cardiac growth	CDKN1B	HMBOX1	HIPK1	HIPK2	
G13 SIGNALING%WIKIPATHWAYS_20260910%WP524%HOMO SAPIENS	G13 signaling	ARHGDIB	CYFIP1	WAS	PIP4K2A	MAPK10	RTKN	SH3RF1	PPP1CB	RHPN2	RHOA	MYBPH	PKN1	CIT	RPS6KB1	MAP3K4	PFN1	ROCK1	ROCK2	CDC42	CFL2	PAK3	CFL1	TNK2	LIMK1	DIAPH1	PIK3CD	PIK3CB	GNA13	ARHGEF1	IQGAP1	ARHGDIG	IQGAP2	PIK3R2	PIK3CA	CALM1	WASL	RAC1	MYL1	
VEDOLIZUMAB THERAPY FOR INFLAMMATORY BOWEL DISEASE%WIKIPATHWAYS_20260910%WP5512%HOMO SAPIENS	Vedolizumab therapy for inflammatory bowel disease	ITGA2	ITGB2	SELPLG	VCAM1	SELE	MADCAM1	ITGB7	ITGB1	ICAM1	ITGA4	
ENDOTHELIN PATHWAYS%WIKIPATHWAYS_20260910%WP2197%HOMO SAPIENS	Endothelin pathways	PRKCA	GNAI1	GNG13	NPY	PTGIR	NPY1R	GNAS-1	EDN1	PLCB1	ATP2A2	CNN1	RIIAD1	ADRA1A	RAMP1	CALCA	ADRB1	RAF1	GNA15	MYLK	CALCRL	CAD	NOS3	ADCY10	GNB5	ECE1	EDNRA	EDNRB	MAP2K2;MAP2K1	CALM1	MAPK1	MYL1	
ETHANOL METABOLISM PRODUCTION OF ROS BY CYP2E1%WIKIPATHWAYS_20260910%WP4269%HOMO SAPIENS	Ethanol metabolism production of ROS by CYP2E1	MAFG	MAFK	CYP2E1	MAPK8	SP1	MAP2K2;MAP2K1	MAFF	NFE2L2	
NON HOMOLOGOUS END JOINING%WIKIPATHWAYS_20260910%WP438%HOMO SAPIENS	Non homologous end joining	XRCC6	NHEJ1	XRCC4	XRCC5	LIG4	PRKDC	POLM	POLL	WRN	DCLRE1C	
CILIOPATHIES%WIKIPATHWAYS_20260910%WP4803%HOMO SAPIENS	Ciliopathies	TCTN2	CSPP1	GAS8	TCTN1	BBS9	LCA5	BBS7	CEP290	CLUAP1	CC2D2A	BBS5	RPGRIP1L	TMEM138	RP2	CCDC65	TMEM216	ANKS6	CEP104	ARL3	ARL13B	TMEM67	INPP5E	NPHP1	PDE6D	NPHP3	AHI1	PIBF1	RSPH9	NEK8	BBS2	BBS1	NEK9	MKS1	CPLANE1	TMEM231	TTC8	TMEM17	RSPH3	KIAA0586	TMEM237	UNC119	B9D1	EVC2	CEP41	B9D2	TTC21B	GLI2	KIF7	EVC	INVS	RSPH4A	RSPH1	KIAA0753	OFD1-1	OCRL	BBS4	ZIC2	CRX	ODAD1	GALNT11	ODAD3	ODAD2	ODAD4	MCIDAS	TBC1D32	NEK1	NEK2	DNAAF3	ADCY6	IFT172	DNAAF2	DNAAF1	DNAAF6	DNAAF5	DNAAF4	CFAP410	RP1-2	FAM161A	MAK	CFAP298;CFAP298-TCP10L	CCNQ	TRAF3IP1	CCNO	AK7	GLIS2	PKHD1	CEP78	INTU	DNAH11	CEP19	DCDC2	C8orf37	GPR161	ARL2BP	DNAL1	ALMS1	WDPCP	HYDIN	TAPT1	CCDC39	ARL6	DDX59	BBIP1	CFAP52	TTBK2	DNAI2	POMGNT1	TOPORS	NME7	NME9	USP9X	CEP83	EFHC1	ZMYND10	SMO	KIZ	C2CD3	CFAP53	KATNIP	CCDC103	PKD2	TMEM107	DNAH6	MKKS	PKD1L1	POC1A	BBS10	POC1B	PIK3R4	BBS12	RAB28	XPNPEP3	CILK1	DNAI1	TUB	PCARE	RPGRIP1	RAB23	RP1L1	SCLT1	TTLL5	CNGA1	CENPF	SPAG1	HYLS1	ATXN10	TRIM32	DYNC2H1	DYNC2I2	PLK4	LZTFL1	DYNC2I1	CNGB1	IFT140	SPATA7	DYNLT2B	WDR19	IFT122	IFT80	WDR35	DYNC2LI1	IFT43	IFT81	IFT27	PKD1	TULP1	GLI3	DRC1	IFT52	ZNF423	IFT57	IQCB1	DNAJB13	FLCN	CCDC40	CEP120	CEP164	TCTN3	
PRION DISEASE PATHWAY%WIKIPATHWAYS_20260910%WP3995%HOMO SAPIENS	Prion disease pathway	MAPK3	RXRA	SPI1	STAT3	ELK1	EP300	SMC3	PDIA3	POU2F2	RFX5	BATF	CASP3	BCL2	EBF1	RAD21	CREB1	FGFR1	FYN	PAX5	PRNP	IRF4	HSP90B1	NCAM1	HSPA5	BCL11A	PTK2	CTCF	MEF2C	TBP	CHD2	NFKB1	MAPK1	
RIOK1 AND RIOK2 IN EGFR AND PI3K MEDIATED TUMORIGENESIS%WIKIPATHWAYS_20260910%WP3873%HOMO SAPIENS	RIOK1 and RIOK2 in EGFR and PI3K mediated tumorigenesis	RPL11	MAPKAP1	MLST8	PTEN	FOXO3	AKT2	AKT3	AKT1	TP53	MTOR	EGFR	RICTOR	RIOK2	PIK3CA	RIOK1	
MYD88 DISTINCT INPUT OUTPUT PATHWAY%WIKIPATHWAYS_20260910%WP3877%HOMO SAPIENS	MYD88 distinct input output pathway	MYD88	TRAF6	IL1A	TLR1	TLR9	TLR5	TLR8	TLR6	TLR2	TLR7	TLR10	TLR4	IRAK1	UBE2N	JUN	NFKB1	TIFA	UBE2V1	
PI3K AKT SIGNALING%WIKIPATHWAYS_20260910%WP4172%HOMO SAPIENS	PI3K Akt signaling	CD19	PRKAA1	ATF2	IKBKB	FGF21	JAK3	CHUK	RHEB	RELA	PRKAA2	EGF	FN1	EPO	TNC	CCND1	MYC	KDR	PDGFB	PDGFRB	FGF2	ATF4	KIT	IGF1	EIF4E	BCL2	CREB3L2	RAF1	AKT2	AKT3	AKT1	MTOR	GSK3B	TCL1B	PIK3R2	TCL1A	PIK3R1	PPP2R1B	PPP2R1A	DDIT4	PPP2R2A;PPP2R2D	MAP2K2;MAP2K1	EPHA2	MAPK1	RAC1	LPAR2	JAK2	LPAR3	IL6R	LPAR4	GNG10	PDGFD	MAPK3	PDGFC	JAK1	NGFR	GNG13	SGK3;C8orf44-SGK3	COL1A1	COL1A2	LPAR5	BAD	LPAR6	GYS2	GNGT1	GYS1	IKBKG	OSMR	IL6	PHLPP2	IGF1R	RPS6KB1	TNXB	GRB2	PHLPP1	SOS1	RELN	BCL2L1	VEGFB	OSM	VEGFD	KITLG	FGF20	CHRM2	CSF3R	FGF23	IL2	STK11	FGF22	IBSP	IL4	TNN	FGF17	TNR	PDGFRA	FGF19	F2R	FLT4	COL4A2	TLR4	COL4A1	PTEN	EIF4E1B	COL4A4	COL4A6	FGF1	CSF1R	FGF3	FGF4	SOS2	FGF5	EFNA4	EGFR	FGF6	HSP90B1	FGF7	VTN	FGF8	CHAD	FGF9	EFNA1	EFNA3	EFNA2	FGF14	GNB2	PRKCA	GNB1	RPS6KB2	GNB4	EFNA5	GNB3	IL7R	FGF13	FGF12	FGF11	HSP90AB1	LAMC3	LAMC2	PIK3R3	LAMC1	PIK3R6	GHR	PIK3R5	HSP90AA1	VWF	PPP2R5B	PPP2R5A	PPP2R5D	NGF	COL6A2	IL3RA	EIF4E2	CREB5	LAMA5	LAMA2	LAMA1	LAMA4	LAMA3	THBS2	THBS4	THBS3	ITGA2B	GNG2	GNG5	FGF18	PPP2R3C	PPP2R3B	FGFR4	GNG4	GNG8	FGFR3	EIF4B	FGFR2	ANGPT4	LAMB3	TLR2	FGF10	NOS3	FGFR1	LAMB2	LAMB1	FOXO3	PPP2R3A	BCL2L11	PIK3CD	EPOR	PCK2	PIK3CB	PPP2R2C	G6PC1	PIK3CG	PPP2R2B	FASLG	TEK	PPP2R5E	PPP2R5C	NTRK2	PTK2	PIK3CA	ITGA10	FLT1	ITGA11	ITGB1	PGF	ITGB5	ITGB4	ITGB3	ITGB8	ITGAV	ITGB7	ITGB6	ITGA4	PKN3	PDPK1	ITGA3	ITGA2	PKN2	ITGA1	CDKN1A	PKN1	CDKN1B	ITGA8	G6PC2	BRCA1	G6PC3	ITGA7	NTF4	ITGA6	FLT3LG	CASP9	ITGA5	CCND3	CCND2	ITGA9	COMP	CREB1	COL9A1	CCNE2	COL9A3	COL9A2	CCNE1	IFNB1-4	TP53	GNB5	MDM2-2	IL3	IL7	LAMB4	CDK6	CDK4	CDK2	CHRM1	IRS1	BDNF	INS;INS-IGF2	PPP2CB;PPP2CA	IFNAR2	TSC2	FLT3	RBL2	IFNAR1	PRL	IL2RG	RPS6	IL4R	PRLR	NFKB1	EIF4EBP1	IL2RA	IL2RB	CSF3	NTRK1	HGF	SGK1-1	CREB3L3	CREB3L4	CREB3L1	SYK	PDGFA	TGFA	INSR	ATF6B	SPP1	MYB	CSF1	VEGFA	MCL1	LPAR1	IGF2	NRAS	HRAS	KRAS	THEM4	COL6A1	COL6A3	COL6A6	COL6A5	PCK1	PIK3AP1	MET	RPTOR	COL4A3	COL4A5	NTF3	MLST8	COL2A1	CDC37	ANGPT2	TSC1	ANGPT1	THBS1	VEGFC	CREB3	
MAJOR RECEPTORS TARGETED BY EPINEPHRINE AND NOREPINEPHRINE%WIKIPATHWAYS_20260910%WP4589%HOMO SAPIENS	Major receptors targeted by epinephrine and norepinephrine	ADCY6	ADRB2	ADCY3	ADCY5	ADCY8	ADRA2C	ADRA2B	ADRA2A	ADCY10	ADCY9	ADCY1	ADCY4	ADCY2	ADRB1	ADRA1D	ADCY7	
H19 RB E2F1 AND CDK BETA CATENIN IN COLORECTAL CANCER%WIKIPATHWAYS_20260910%WP3969%HOMO SAPIENS	H19 Rb E2F1 and CDK beta catenin in colorectal cancer	CSRP2	CCND1	CDH1	MACROH2A1	CDK4	TULP3	MED1	CTNNB1	RB1	E2F1	CDK8	PMAIP1	JAG1	SOX4	
METHIONINE METABOLISM LEADING TO SULFUR AMINO ACIDS AND RELATED DISORDERS%WIKIPATHWAYS_20260910%WP4292%HOMO SAPIENS	Methionine metabolism leading to sulfur amino acids and related disorders	BHMT	ADK	CSAD	AHCY	MAT1A	MAT2B	CTH	MTR-1	GNMT	CDO1	CBS;CBSL	
NITRIC OXIDE METABOLISM IN CYSTIC FIBROSIS%WIKIPATHWAYS_20260910%WP4947%HOMO SAPIENS	Nitric oxide metabolism in cystic fibrosis	PRMT6	PRMT8	PRMT7	NOS2	PRMT3	DDAH2	NOS1	NOS3	PRMT5	DDAH1	PRMT2	PRMT1	CARM1	
17P13 3 YWHAE COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5376%HOMO SAPIENS	17p13 3 YWHAE copy number variation	NDEL1	CDK5	DCTN3	PAFAH1B1	DCTN1	YWHAE	YWHAB	TH	YWHAQ	DCTN6	YWHAH	DDC	DCTN4	YWHAG	DYNC1H1	YWHAZ	DCTN5	DCTN2	PPP2CB;PPP2CA	DISC1	DBH	
7Q11 23 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP4932%HOMO SAPIENS	7q11 23 copy number variation syndrome	TRIM74;TRIM73;TRIM50	TMEM270	GAPDH-1	DDX21	CTNNB1	RB1	CLDN4	CLDN5	CLDN3	DLD	DLST	MYC	SNAP25	ULK1	CLTC	ATF4	UBE2L6	EIF2AK3	HDAC6	VAMP2	HDAC2	MYBBP1A	FAS	SF3B1	ACACA	RFC5	ACACB	RFC2	OGDH	BRD4	STX1A	ATP5MC2	ATP5MC3	EIF2A	ATP5MC1	ATP5F1A	UBE2E1	ATP5F1B	NUP62	HDAC3	MAPK3	PRKG1	BAZ1B	ATP5PB	MYO1C	ATP5F1D	ERCC6	ATP5PO	SMARCA5	DEK	CDKN1C	GRB2	FBN1	USF1	BTK	BECN1	CFL1	PKLR	NRG1	SQSTM1	GRIP1	HSPA2	WNT2	EIF4H	CLDN1	FZD9	CLASP1	ABHD11	LIMK1	GTF2I	UBE2E3	CLIP2	DNAJC30	FKBP6	VPS28	UBIAD1	TSG101	ATPAF2-2	FBLN2	FBLN5	HOXC8	TBL2	GTF2IRD1	BCL7B	PCNA	BUD23	VPS9D1	VPS37C	VPS37D	VPS37A	VPS37B	LAT2	CHTF18	METTL27	ATPAF1	MVB12A	CLASP2	
TRANS SULFURATION PATHWAY%WIKIPATHWAYS_20260910%WP2333%HOMO SAPIENS	Trans sulfuration pathway	GOT1-1	GCLM	DNMT1	CSAD	AHCY	MAT2B	CTH	MTR-1	MPST	CBS;CBSL	
GLUCURONIDATION%WIKIPATHWAYS_20260910%WP698%HOMO SAPIENS	Glucuronidation	PGM2	UGT2A1	PGM5	UGDH	UGP2	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	PGM1	HK1	UGT1A1;UGT1A6	PGM3	
GLYOXYLATE METABOLISM%WIKIPATHWAYS_20260910%WP5166%HOMO SAPIENS	Glyoxylate metabolism	ALDH4A1	LDHA	SLC26A1	PXMP2	GOT2-1	HAO1	GRHPR	HOGA1	DAO	PRODH2	AGXT	
ROLES OF CERAMIDES IN DEVELOPMENT OF INSULIN RESISTANCE%WIKIPATHWAYS_20260910%WP5181%HOMO SAPIENS	Roles of ceramides in development of insulin resistance	SLC2A4	INSR	ACSL1	MAPK8	CD36	PRKCZ	TNF	AKT1	MAFA	TNFRSF1A	SMPD3	ERN1	IRS1	RPS6KB1	EIF2AK2	IRS2	TRAF1	PIK3R1	CPT1B	INS;INS-IGF2	PPP2CB;PPP2CA	PDX1	PRKAG3	
EXTRACELLULAR VESICLES IN THE CROSSTALK OF CARDIAC CELLS%WIKIPATHWAYS_20260910%WP4300%HOMO SAPIENS	Extracellular vesicles in the crosstalk of cardiac cells	CD63	SPP1	SOD1	BIRC5	KDR	CD81	SORBS2	ETS2	STAT3	PTEN	TLR4	GATA4	HSPB1	IL6	EGFR	MMP9	PDLIM5	EGF	IGF1	
SEROTONIN AND ANXIETY RELATED EVENTS%WIKIPATHWAYS_20260910%WP3944%HOMO SAPIENS	Serotonin and anxiety related events	PLCD4	NLGN1	HTR2A	FOS	PPP3CA	ARC	PLEK	GRIN2D	CRHR1	PRKCB	CRH	HTR1A	
BIOSYNTHESIS AND TURNOVER OF 1 DEOXY SPHINGOID BASES%WIKIPATHWAYS_20260910%WP5179%HOMO SAPIENS	Biosynthesis and turnover of 1 deoxy sphingoid bases	ASAH1	KDSR	SGPP1	SPHK2	SPHK1	SGPP2	SPTLC1	
DEVELOPMENT OF URETERIC DERIVED COLLECTING SYSTEM%WIKIPATHWAYS_20260910%WP5053%HOMO SAPIENS	Development of ureteric derived collecting system	EYA1	BMP4	GRIP1	BMP2	SMO	WNT11	ETV5	GDNF	CELSR1	BMPER	GPC3	CRIM1	RET	GFRA1	BMP5	CTDNEP1	FRAS1	FREM1	FREM2	ITGA8	SMAD1	ANOS1-1	GLI1	CCND1	SIX1	SALL1	SIX2	RARG	BMPR1A	FST	BMP7	BMPR2	GLI2	SHH	GDF11	GLI3	HOXD11	DCN	HOXA11	PAX2	RARA	RARB	TGFB2	ETV4	SPRY1	TGFB1	MYCN	VANGL2	
GLYCOLYSIS AND GLUCONEOGENESIS%WIKIPATHWAYS_20260910%WP534%HOMO SAPIENS	Glycolysis and gluconeogenesis	GOT1-1	SLC2A1	PC	ALDOA	HK2	LDHA	GAPDH-1	PGAM1	PKM	PGK1	SLC2A2	ALDOC	ENO1	HK1	PFKM	HK3	SLC2A5	GCK	ENO2	DLAT	ENO3	MPC2	PFKP	DLD	FBP2	LDHAL6B	TPI1	PCK1	SLC2A4	PFKL	ALDOB	LDHB	PDHA1	FBP1	LDHA;LDHC	MPC1	PKLR	PGAM2	G6PC1	MDH2	MDH1	GOT2-1	GPI	
ACTIVATION OF NLRP3 INFLAMMASOME BY SARS COV 2%WIKIPATHWAYS_20260910%WP4876%HOMO SAPIENS	Activation of NLRP3 inflammasome by SARS CoV 2	IL1B	PYCARD	CASP1	NLRP3	RELA	TRAF3	NFKB1	
EICOSANOID SYNTHESIS%WIKIPATHWAYS_20260910%WP167%HOMO SAPIENS	Eicosanoid synthesis	ALOX15	GGT1	ALOX12	PLA2G5	LTC4S	PLA2G6	PTGS1	DPEP1	JMJD7-PLA2G4B;PLA2G4B	ALOX5	LTA4H	PTGDS	CBR1-1	PTGIS	PTGES2	PLA2G4A	ALOX15B	PRXL2B	ALOX5AP	TBXAS1	PTGS2-2	PTGES	
RENIN ANGIOTENSIN ALDOSTERONE SYSTEM RAAS %WIKIPATHWAYS_20260910%WP4756%HOMO SAPIENS	Renin angiotensin aldosterone system RAAS	CAMK2B	ITPR2	CAMK2D	CYP11A1	CAMK2A	REN	ATF2	CAMK2G	AGT	GNAQ	PLCB2	CREB3L3	CREB3L4	CREB5	CALML6	CREB3L1	CALML3	CAMK1D	CALML4	CAMK1G	CYP11B1;CYP11B2	CREB3L2	CTSG	CALM3;CALM1	ATF6B	STAR	ATF1	HSD3B1;HSD3B2	CMA1	CREB1	CAMK1	CAMK4	ATF4	ACE	AGTR1	AGTR2	CREB3	CYP21A2	ITPR1	CALM1	CALM2	ITPR3	
TYROSINE KINASE INHIBITORS IN GLIOBLASTOMA%WIKIPATHWAYS_20260910%WP5494%HOMO SAPIENS	Tyrosine kinase inhibitors in glioblastoma	JAK2	JAK1	EREG	BTC	NRAS	HRAS	STAT3	TYK2	JAK3	RHEB	KRAS	GRB2	SOS1	EGF	RAF1	TGFA	RPTOR	TSC2	PDK1	PTEN	AKT2	AKT3	AKT1	MTOR	TSC1	SOS2	
FEMALE STEROID HORMONES IN CARDIOMYOCYTE ENERGY METABOLISM%WIKIPATHWAYS_20260910%WP5318%HOMO SAPIENS	Female steroid hormones in cardiomyocyte energy metabolism	SLC2A4	ACADM	SOD2	STK11	ACLY	NOS3	AKT2	PPARA	MTTP	HADHB-1	ESRRA	APOB	ESR1	PPARGC1B	
TLR4 SIGNALING AND TOLERANCE%WIKIPATHWAYS_20260910%WP3851%HOMO SAPIENS	TLR4 signaling and tolerance	MYD88	TRAF6	MAP3K7	IRF3	IKBKB	RIPK1	IRAK3	IKBKG	CHUK	TICAM1	IL6	INPP5D	TRAF3	NFKBIA	CXCL8	TIRAP	TRAM1	TLR4	TNF	IFNB1-4	IRAK1	TBK1	IRF7	IRAK4	IKBKE	NFKB1	TAB2	TAB1	
NICOTINE EFFECT ON CHROMAFFIN CELLS%WIKIPATHWAYS_20260910%WP1603%HOMO SAPIENS	Nicotine effect on chromaffin cells	CACNA1C	CHRNB4	CHRNA3	CACNA1G	
RANKL RANK SIGNALING%WIKIPATHWAYS_20260910%WP2018%HOMO SAPIENS	RANKL RANK signaling	TRAF6	MAP3K7	MAPK9	MAPK3	STAT1	MAPK14	SPI1	IKBKB	IKBKG	CHUK	GAB2	FOS	CBL	TNFSF11	RELA	TRAF2	LYN	SYK	PAPSS2	NFKBIA	MITF	SRC	CDC42	RELB	SQSTM1	TAB2	TAB1	MAPK8	PLCG1	MAP2K7	TRAF5	TRAF1	MAP2K6	JUN	TRAF3	TNFRSF11B	TNFRSF11A	NFATC1	AKT2	AKT1	MTOR	PIK3R2	PIK3R1	PTK2	FHL2	MAP2K2;MAP2K1	NFKB1	MAPK1	NFKB2	RAC1	
DIET DEPENDENT TRIMETHYLAMINE TRIMETHYLAMINE N OXIDE METABOLISM %WIKIPATHWAYS_20260910%WP5219%HOMO SAPIENS	Diet dependent trimethylamine trimethylamine N oxide metabolism	FMO3	CHDH	ALDH7A1	SLC44A1	
SOMITOGENESIS IN THE CONTEXT OF SPONDYLOCOSTAL DYSOSTOSIS%WIKIPATHWAYS_20260910%WP4785%HOMO SAPIENS	Somitogenesis in the context of spondylocostal dysostosis	DLL1	DLL3	EPHA4	MESP2	NOTCH1	LFNG	TBX6	HES7	RIPPLY2	
ELECTRON TRANSPORT CHAIN OXPHOS SYSTEM IN MITOCHONDRIA%WIKIPATHWAYS_20260910%WP111%HOMO SAPIENS	Electron transport chain OXPHOS system in mitochondria	NDUFA9	DMAC2L	ATP5PF	UCP1	NDUFA8	NDUFA7	NDUFA6	ATP5PD	NDUFA5	NDUFA4	ATP5PB	NDUFA3	ATP5F1D	NDUFAB1	ATP5PO	NDUFS5-1	UQCRB	NDUFA12	UQCR11	COX6A1	UQCR10	COX6A2	SDHC	SDHD	UQCRQ	SDHA	UQCRC1	UQCRFS1	SDHB	SLC25A5	COX6B1	SLC25A6	UQCRC2	COX7A2	ATP5IF1	COX7B	SLC25A14	COX4I1	SLC25A27	UCP3	COX7C	UCP2	ATP5F1C	COX8A	COX7A2L-1	NDUFB3	COX5B	COX5A	COX6C	SLC25A4	COX11	NDUFA11	NDUFA10	NDUFA13	NDUFC1	NDUFS8	NDUFS7	NDUFS6	NDUFS4	NDUFS3	NDUFS2	NDUFS1	NDUFB9	NDUFB8	NDUFB7	NDUFB10	NDUFB6	NDUFB5	COX17	NDUFB4	NDUFB2	ATP5MC2	NDUFB1	SCO1	ATP5MC3	ATP5MC1	ATP5F1A	ATP5F1B	NDUFC2;NDUFC2-KCTD14	NDUFV3	SURF1	NDUFV2	ATP5MG	COX15	NDUFV1	ATP5ME	
DNA MISMATCH REPAIR%WIKIPATHWAYS_20260910%WP531%HOMO SAPIENS	DNA mismatch repair	RFC1	POLE2	RPA3	POLE3	POLD3	POLD4	POLD1	POLD2	LIG1	PMS2	PCNA	EXO1	MSH6	RPA1	POLE	RFC5	MSH2	RFC3	RFC4	RPA2	MLH1	RFC2	POLE4	
HEPATOCYTE GROWTH FACTOR RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP313%HOMO SAPIENS	Hepatocyte growth factor receptor signaling	RASA1	MAPK3	MAPK8	HRAS	STAT3	ELK1	GAB1	PTPN11	MAP4K1	ITGA1	HGF	FOS	RAPGEF1	GRB2	PTGS2-2	JUN	SOS1	CRK	DOCK1	CRKL	SRC	RAF1	MET	PAK1	PTEN	PXN	RAP1B	RAP1A	PTK2B	PTK2	PIK3CA	ITGB1	MAP2K2;MAP2K1	MAPK1	
HIPPO YAP SIGNALING%WIKIPATHWAYS_20260910%WP4537%HOMO SAPIENS	Hippo YAP signaling	CXCL10	MINK1	STK38L	TNIK	STK3	SAV1	YAP1-1	TEAD1	WWTR1	MAP4K3	TEAD3	MAP4K4	TEAD4	LATS2	MAP4K1	MAP4K2	MST1	NDRG1	LATS1	NF2	TEAD2	RASSF1	
HOST PATHOGEN INTERACTION OF HUMAN CORONAVIRUSES AUTOPHAGY%WIKIPATHWAYS_20260910%WP4863%HOMO SAPIENS	Host pathogen interaction of human coronaviruses autophagy	ATG16L1	ATG13	ZFYVE1	ATG16L2	PIK3R4	ULK2	ULK1	MTOR	MAP1LC3A	ATG3	RB1CC1	ATG10	WIPI1	ATG12-1	PIK3C3	BECN1	ATG4A	ATG7	ATG5	
ARIPIPRAZOLE METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP2640%HOMO SAPIENS	Aripiprazole metabolic pathway	CYP2D6;LOC107987479;LOC107987478-1	
BLOOD CLOTTING CASCADE%WIKIPATHWAYS_20260910%WP272%HOMO SAPIENS	Blood clotting cascade	SERPINE1	SERPINB2	KLK1	PLAT	F11	PLAU	F10	VWF	FGB	FGA	F13B	FGG	SERPINF2	F12	F2	F3	F7	F5	PLG	F8	KLKB1	F9	
MIRNA REGULATION OF PROSTATE CANCER SIGNALING%WIKIPATHWAYS_20260910%WP3981%HOMO SAPIENS	miRNA regulation of prostate cancer signaling	CREBBP	AR	BAD	CTNNB1	IKBKG	CDKN1A	CDKN1B	KRAS	GRB2	CASP9	FOXO1-1	CREB3L1	SOS1	NFKBIA	BCL2	TCF7	PDGFA	RAF1	CCND1	PDGFRB	AKT3	TP53	MDM2-2	MTOR	GSK3B	PIK3CA	MAP2K2;MAP2K1	KLK3;KLK2	NFKB1	MAPK1	
LNCRNA IN CANONICAL WNT SIGNALING AND COLORECTAL CANCER%WIKIPATHWAYS_20260910%WP4258%HOMO SAPIENS	lncRNA in canonical Wnt signaling and colorectal cancer	MAP3K7	ATF3	MACROH2A2	WNT11	DKK1	HNRNPU	SOST	WNT7B	PLAU	TFAP2A	CTNNB1	TPTEP2-CSNK1E;CSNK1E	FRAT2	CSNK2A2	CCND3	SFRP4	CCND2	CSNK2B	TCF7	DVL1	DVL2	FOSL1	HNRNPK	CCND1	MYC	DVL3	DKK2	DKK4	RUVBL1	FZD10	APC2	AXIN1	AXIN2	CSNK2A1;CSNK2A3	SOX17	CER1	LEF1	SERPINF1	CTNNBIP1	SFRP1	SFRP2	SFRP5	CTBP2	CTBP1	TCF7L2	PORCN	TCF7L1	WNT5B	CSNK1A1	RYK-1	APC	KREMEN1	SENP2	ROR1	ROR2	CDK6	CXXC4	NKD1	NKD2	WIF1	NOTUM	EZH2	WNT6	WNT1	WNT2	WNT4	WNT10B	WNT10A	FZD2	JUN	FZD5	FZD7	FZD6	FZD9	FZD8	FZD1	FZD3	WNT3A	WNT5A	WNT7A	CHD8	WNT2B	WNT3	LRP6	GSK3B	CDK8	WNT16	NLK	LRP5	
STEROID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP496%HOMO SAPIENS	Steroid biosynthesis	HSD17B1	F13B	HSD17B2	HSD17B3	CYP17A1	HSD3B1;HSD3B2	CPN1	HSD17B7	HSD17B4	
CHOLESTEROL SYNTHESIS DISORDERS%WIKIPATHWAYS_20260910%WP5193%HOMO SAPIENS	Cholesterol synthesis disorders	SQLE	HSD3B1;HSD3B2	IDI1	CYP51A1	EBP	MVK	SC5D	DHCR24	MSMO1	DHCR7	LBR	MVD	HMGCR	HMGCS1-1	PMVK	FDFT1	FDPS	LSS	
GENES ASSOCIATED WITH THE DEVELOPMENT OF RHEUMATOID ARTHRITIS%WIKIPATHWAYS_20260910%WP5033%HOMO SAPIENS	Genes associated with the development of rheumatoid arthritis	IL2RA	CCR6	ITGAV	BLK	SLC22A4	CIITA	FCRL3	PTPN22	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	PADI4	CD244	PHF19	CTLA4	IRF5	TRAF1	IL6ST	CD40	STAT4	
TGIF DISRUPTION OF SHH SIGNALING%WIKIPATHWAYS_20260910%WP3674%HOMO SAPIENS	Tgif disruption of Shh signaling	SMAD2;SMAD3	GLI3	TGIF2	FGF8	FOXG1	NKX2-1	TGIF1-1	NODAL	SHH	
LACTATE SHUTTLE IN GLIAL CELLS%WIKIPATHWAYS_20260910%WP5314%HOMO SAPIENS	Lactate shuttle in glial cells	SLC2A1	LDHB	LDHA	NUDT14	SLC1A2	SLC4A4	CA2	HK1	CA4	SLC16A1	SLC16A7	SLC16A3	
AMPLIFICATION AND EXPANSION OF ONCOGENIC PATHWAYS AS METASTATIC TRAITS%WIKIPATHWAYS_20260910%WP3678%HOMO SAPIENS	Amplification and expansion of oncogenic pathways as metastatic traits	TNC	VCAM1	NOTCH1	PIK3CG	WNT2	LEF1	POSTN	CYTIP	CXCR4	VEGFA	JAG1	TCF7L2	TCF7L1	VHL	TCF7	EPAS1	SRC	
INCLUSION BODY MYOSITIS%WIKIPATHWAYS_20260910%WP5120%HOMO SAPIENS	Inclusion body myositis	NCSTN	MSTN	SIRT1	PSEN1	MAPT	PSENEN	APP	BACE1	PSEN2	NFKB1	NFKB2	
METABOLISM OF SPHINGOLIPIDS IN ER AND GOLGI APPARATUS%WIKIPATHWAYS_20260910%WP4142%HOMO SAPIENS	Metabolism of sphingolipids in ER and Golgi apparatus	B4GALT1	SGMS1	SGPL1	B3GALT2	B3GALT1	GALNT1	SGPP2	SGMS2	CERS3	UGT8	UGCG	KDSR	CERK	SGPP1	B4GALT2	SPHK2	B4GALNT1	B3GALNT1	SPHK1	GALNT16	ST6GALNAC3	
MEASLES VIRUS INFECTION%WIKIPATHWAYS_20260910%WP4630%HOMO SAPIENS	Measles virus infection	HSPA6	IRF3	MAPK9	MAVS	IKBKB	MAPK10	JAK3	CHUK	CDKN1B	FOS	BBC3	RELA	CASP9	EIF3H	CCND3	CCND2	STAT5A	STAT5B	NFKBIA	CASP3	CCND1	HSPA8	APAF1	CCNE2	CCNE1	IFNB1-4	TP53	CYCS-1	IRAK1	EIF2AK3	EIF2AK2	BID	RCHY1	CLEC4M;CD209-2	TAB2	RAB9A	NECTIN4	RAB9B	MYD88	CDK6	IL1B	CDK4	CDK2	MAPK8	SLAMF1	CASP8	FAS	BAX	TRADD	FADD	JUN	BCL2	IFNAR2	STAT2	ADAR	MX1-1	OAS1	IRF9	IFNAR1	IL2RG	PIK3R2	PIK3R1	IRAK4	NFKB1	NFKB2	RACK1	TRAF6	CBLB	MAP3K7	IL2RA	IL2RB	NFKBIB	JAK1	STAT1	BAD	CD3G	STAT3	IL12B	EIF2S1	CD3E	TYK2	IKBKG	IL6	CD3D	CSNK2A2	CSNK2B	BCL2L1	MSN	IL2	IL1A	OAS3	TLR9	IL12A	TLR7	TLR4	CSNK2A1;CSNK2A3	EIF2AK1	EIF2AK4	IRF7	BAK1	CD28	HSPA2	PIK3R3	TRAF3	TNFAIP3	TLR2	PIK3CD	PIK3CB	TP73	HSPA1A;HSPA1B	FASLG	IFIH1	TBK1	PIK3CA	HSPA1L	IKBKE	DDX58	
VITAMINS A AND D ACTION MECHANISMS%WIKIPATHWAYS_20260910%WP4342%HOMO SAPIENS	Vitamins A and D action mechanisms	RARA	RXRA	VDR	
COPPER METABOLISM%WIKIPATHWAYS_20260910%WP5189%HOMO SAPIENS	Copper metabolism	ATP7B	ATP7A	SLC11A2	SLC31A1	
STING PATHWAY IN KAWASAKI LIKE DISEASE AND COVID 19%WIKIPATHWAYS_20260910%WP4961%HOMO SAPIENS	STING pathway in Kawasaki like disease and COVID 19	IRF3	NFKBIE	IL1B	NLRX1	STING1	IFNB1-4	IKBKB	CHUK	IKBKG	CGAS	REL	RELA	NLRP3	F3	TBK1	ITPR1	NFKBIA	NFKB1	IKBKE	GSDMD	
FAS LIGAND PATHWAY AND STRESS INDUCTION OF HEAT SHOCK PROTEINS%WIKIPATHWAYS_20260910%WP314%HOMO SAPIENS	Fas ligand pathway and stress induction of heat shock proteins	ARHGDIB	NFX1	MAP3K7	MAPKAPK2	LMNA	MAP2K4	PRKDC	MAPK8	CASP8	FAS	PARP1	FADD	RB1	LMNB1	ACTG1	ACTA1	CASP9	JUN	MAP3K1	CASP3	BCL2	DFFB	DFFA	PAK1	FAF1	APAF1	PAK2	IL1A	RIPK2	CFLAR	TNF	ACTB-1	CYCS-1	HSPB1	FASLG	DAXX	CASP7	CASP6	CASP10	MAPKAPK3	LMNB2	SMIM40	SPTAN1	
CONSTITUTIVE ANDROSTANE RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2875%HOMO SAPIENS	Constitutive androstane receptor pathway	DNAJC7	EHHADH-1	CYP2B6	NCOA1	RXRA	CYP2A13;CYP2A6;CYP2A7-1	NCOA6	PPARGC1A	ALAS1	HSP90AA1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	ABCC3	NR1I3	ABCC2	FOXO1-1	GSTA3;GSTA5;GSTA1;GSTA2	PTPA	SMC1A	SP1	NCOA2	CYP2C9;CYP2C19	UGT1A1;UGT1A6	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	SULT2A1-4	ABCB1	
APOPTOSIS REGULATION BY PARATHYROID HORMONE RELATED PROTEIN%WIKIPATHWAYS_20260910%WP3872%HOMO SAPIENS	Apoptosis regulation by parathyroid hormone related protein	BCL2L12	MYC	BCL2L13	BCL2L14	BCL2L15	BOK	BCL2L10	BAX	AKT2	BCL2A1	AKT3	AKT1	BCL2L2	PIK3CG	GSK3B	ITGA6	BAK1	BID	GSK3A	MCL1	BCL2L1	BCL2	ITGB4	PTHLH	
INTERACTIONS OF NATURAL KILLER CELLS IN PANCREATIC CANCER%WIKIPATHWAYS_20260910%WP5092%HOMO SAPIENS	Interactions of natural killer cells in pancreatic cancer	CCL4L2;CCL4L1;CCL4	MYC	BMI1	CD96	CSF2	PVR	NCR1-1	PRF1	IFNG	NCR3LG1-1	CCL5	CCL1	TNF	CD226	GATA2	TIGIT	CCL13;CCL2	ADAM17	FCGR3A;FCGR3B	KLRC4-KLRK1;KLRK1	FOXO1-1	GZMH;GZMB-1	CCL3L1;CCL3L3;CCL3;CCL18	ADAM10	
CELLS AND MOLECULES INVOLVED IN LOCAL ACUTE INFLAMMATORY RESPONSE %WIKIPATHWAYS_20260910%WP4493%HOMO SAPIENS	Cells and molecules involved in local acute inflammatory response	C3-1	ITGB2	SELPLG	VCAM1	ITGAL	KNG1	IL1A	SELP	C6	C7	ICAM1	ITGA4	TNF	IL6	ITGB1	C5	CXCL8	
ASPIRIN AND MIRNAS%WIKIPATHWAYS_20260910%WP4707%HOMO SAPIENS	Aspirin and miRNAs	MVD	WNT1	ABCC4	PPARA	PTGS1	PTGS2-2	VEGFA	NOS3	PDK1	NFKB1	
SPHINGOLIPID METABOLISM INTEGRATED PATHWAY%WIKIPATHWAYS_20260910%WP4726%HOMO SAPIENS	Sphingolipid metabolism integrated pathway	PLPP2	SGMS1	DEGS2	ASAH1	CERS3	CERS5	CERS6	CERK	CERS1	SPHK2	SPHK1	SGPL1	SGPP2	PLPP1	SPTLC1	SGMS2	UGT8	UGCG	KDSR	CERS4	SGPP1	DEGS1	CERS2	SMPD1	PLPP3	
GABA AND GLUTAMATE SIGNALLING IN EPILEPTOGENESIS%WIKIPATHWAYS_20260910%WP5600%HOMO SAPIENS	GABA and glutamate signalling in epileptogenesis	GAPDH-1	GRM3	MBD5	SDCBP	SLC6A8	ORAI1	HOMER1	SRC	CACNG8	CACNG2	AP2A1	AP2A2	GRIN2A	GRIN2C	GRIN2B	GRIN2D	SLC32A1	GLUL	AP2B1	SLC1A6	GLS2	GRIA3	GAD1	GRIA4	SLC1A3	FRMPD3	ABAT	GRM5	ADARB1	GRIK5	ZFYVE27	GRIK3	CRTC1	SH3GL2	GRIK4	SLC6A12	GRIK1	SLC1A7	GRIK2	NETO2	CPEB3	GRM2	GRM4	NPTN	GRM7	C1QL3	GRM8	C1QL2	PLCB1	NWD1	SNX27	UBQLN4	ATAD1	SYVN1	LHFPL4	SNX14	PPP2CB;PPP2CA	NR4A1	SLC12A5	SLC6A1	CABIN1	GRIN1	GRM6	KIF5C	GRIN3B	GRIN3A	HDAC1	GABRR3	GABRR2	GABRR1	MAP2K2;MAP2K1	MAPK1	SUMO1	MAPK3	CREBBP	GNA11	STAT1	ERBB4	STAT3	P4HB	CDH2	SLC7A11	SLC1A2	SLC6A6	SLC1A1	GABRB3	MAP1LC3B2;MAP1LC3B-1	GABRB2	GABRB1	GABRG3;GABRG2	NRG1	GABRE	GABRD	GABRQ	GABRA2	PRKCA	GABRA1	GRIP1	GABRP	GABRA6	GRIA1	GABRA5	GABRA4	GABRA3	SLC6A11	GABRG1	CAMK2A	EFNB2	NRXN3	GRIA2	GRM1	GNAQ	ARC	DLGAP3	PICK1	DLG4	FFAR1	PDIA2	HDAC10	STIM1	SLC6A13	
EXTRAFOLLICULAR AND FOLLICULAR B CELL ACTIVATION BY SARS COV 2%WIKIPATHWAYS_20260910%WP5218%HOMO SAPIENS	Extrafollicular and follicular B cell activation by SARS CoV 2	MS4A1	C3-1	ITGB2	CD19	PDCD1	CD79A	ITGAX	ISG15	TNFSF13B	LOC110384692;C4A;C4B_2;C4B	IL6	CR2	PTPRC	SYK	STAT5A	EBI3	IL10	HSPA8	SH2D1A	IL2	IL4	IFNG	CD40LG	IL12A	TLR7	TLR4	TNF	CXCL13	CR1L;CR1	BCR	XBP1	CXCR5	IFIT2	CCL19	CCL21	LOC102723996;ICOSLG	BTLA	ICOS	IL21	CXCR4	FOXO1-1	CXCL12	ETS1	BACH2	BLNK	CD40	PTCRA	FCRL5	IFITM3;IFITM2;IFITM1	CD1D	TBX21	SLAMF7	AICDA	CD22	CCR7	IFNAR2	MAF	CD69	PAX5	ZEB2	MFGE8	BCL6	CD80	TMSB10	CD82	IRF4	IRF8	CRP	GPR183	PRDM1	SELL	
KENNEDY PATHWAY FROM SPHINGOLIPIDS%WIKIPATHWAYS_20260910%WP3933%HOMO SAPIENS	Kennedy pathway from sphingolipids	PCYT1B	SGPL1	PTDSS1	CHKA	PISD	ETNK2	PTDSS2	CEPT1	ETNK1	CHKB	PCYT2	PEMT	CHPT1	PCYT1A	
ENERGY METABOLISM%WIKIPATHWAYS_20260910%WP1541%HOMO SAPIENS	Energy metabolism	MEF2A	MEF2B;BORCS8-MEF2B	PPP3CA	PPP3CB	PRKAA1	NCOA1	PPP3CC	RXRA	MYBBP1A	MAPK14	ATF2	PPARGC1A	TFAM-1	EP300	PPARD	CAMK2G	MED1	SIRT1	PRKAA2	FOXO1-1	ESRRA	PRKAG1	PRKAG2	PRKAG3	PPARGC1B	UCP3	PRKAB2	UCP2	PRKAB1	MEF2D	CREB1	NRF1	FOXO3	TFB2M	CAMK4	TFB1M	PPRC1	PPP3R1	GABPA	PRMT1	SIRT3	PPARA	GSK3B	HDAC1	MEF2C	PPARG	
NAD BIOSYNTHESIS II FROM TRYPTOPHAN%WIKIPATHWAYS_20260910%WP2485%HOMO SAPIENS	NAD biosynthesis II from tryptophan	NADSYN1	NMNAT1	QPRT	HAAO	KMO	TDO2	KYNU	AFMID	
BIOMARKERS FOR UREA CYCLE DISORDERS%WIKIPATHWAYS_20260910%WP4583%HOMO SAPIENS	Biomarkers for urea cycle disorders	GOT1-1	GATM	GPT	GLS2	ASL	NAGS	OTC	GAMT	F7	ARG1	F10	ASS1	
CANONICAL NF KB PATHWAY%WIKIPATHWAYS_20260910%WP4562%HOMO SAPIENS	Canonical NF kB pathway	CHUK	IKBKG	NFKBIE	REL	RELA	NFKBIA	NFKB1	IKBKB	
ATR SIGNALING%WIKIPATHWAYS_20260910%WP3875%HOMO SAPIENS	ATR signaling	TOPBP1	HUS1	RAD9B	RPA3	RPA1	ATRIP	RAD1	RPA2	ATR	CHEK1	RAD9A	
NEUROINFLAMMATION%WIKIPATHWAYS_20260910%WP4919%HOMO SAPIENS	Neuroinflammation	MTOR	CHUK	NOS2	ASCC1	FOS	RELA	MAPK8	JUN	MAPK14	NFKBIA	TLR4	
T CELL RECEPTOR AND CO STIMULATORY SIGNALING%WIKIPATHWAYS_20260910%WP2583%HOMO SAPIENS	T cell receptor and co stimulatory signaling	PRKCA	RASA1	RASGRP1	PPP3CA	PDCD1	PLCG1	NFATC2	ITK	DYRK1A	NFKBIA	PTPN6	LCK	IL2	CD8A	DYRK2	CD8B;CD8B2	FYN	PDK1	PTEN	AKT1	CTLA4	GSK3B	GSK3A	CD28	ZAP70	CSNK1A1	NFKB1	CALM1	
DISORDERS IN KETOLYSIS%WIKIPATHWAYS_20260910%WP5195%HOMO SAPIENS	Disorders in ketolysis	HMGCS1-1	BDH1	OXCT1-1	ACAT1	ACAT2	
HIPPO SIGNALING REGULATION%WIKIPATHWAYS_20260910%WP4540%HOMO SAPIENS	Hippo signaling regulation	CDH5	CDH4	CDH3	CDH20	CDH22	PRKAA1	CDH24	NGFR	CDH10	GNA11	CDH11	CDH12	NTRK1	PRKCD	CDH13	CDH15	CDH17	CDH18	LATS2	CDH19	CTNNB1	CDH6	CDH2	IGF1R	CDH16	PRKAA2	PRKAG1	PRKAG2	PRKAG3	TCF7	PRKACB-1	CDC42	PRKAR2B	PRKAR2A	PRKAB2	INSR	PRKAB1	PRKAR1B	KDR	PRKAR1A	PDGFRA	GNAI3	FLT4	GNAI2	PDGFRB	CSF1R	LEF1	EGFR	KIT	PRKCG	PRKCI	TCF7L2	PRKCH	TCF7L1	PRKCB	PRKCE	PRKCA	PRKCQ	STK3	YAP1-1	TEAD1	PRKCZ	PLCB3	WWTR1	TEAD3	PLCB4	TEAD4	RHOA	GNAS-1	GNAQ	MST1	PLCB1	LATS1	PLCB2	NF2	TEAD2	MET	SMAD2;SMAD3	CDH1	GNAL	FGFR4	PRKACA-1	FGFR3	PRKD3	FGFR2	FLT3	FGFR1	MTOR	TEK	NTRK2	CDH8	FLT1	CDH9	EPHA2	CDH7	RAC1	
MATRIX METALLOPROTEINASES%WIKIPATHWAYS_20260910%WP129%HOMO SAPIENS	Matrix metalloproteinases	TIMP4	MMP1	MMP21	MMP20	MMP25	MMP24	MMP27	MMP2	MMP28	MMP9	MMP7	MMP3	MMP8	MMP10	MMP12	MMP11	MMP14	MMP13	MMP16	TCF20	TIMP1	MMP15	MMP23B	TIMP2	MMP17	TIMP3	MMP19	TNF	BSG	
KCNQ2 AND KCNQ3 RELATED EPILEPSY%WIKIPATHWAYS_20260910%WP5599%HOMO SAPIENS	KCNQ2 and KCNQ3 related epilepsy	VAMP2	FGF13	FGF12	ANK3	CAMK2A	BACE1	SCN4B	KCNQ2	KCNQ3	NEDD4	PRRT2	DAG1	AKAP5	KCNQ1	PRKACA-1	RAB1A	SNAP25	TRAPPC3	SCN2A	TRAPPC2;TRAPPC2B	SCN8A	GIGYF1	TRAPPC6B	KCNQ4	KCNQ5	STX1A	NEDD4L	ITPR1	RAB11A	CALM1	PRKCE	
LEUKOTRIENE METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP5171%HOMO SAPIENS	Leukotriene metabolic pathway	GGT1	LTC4S	DPEP1	PTGR1-1	ALOX5	LTA4H	DPEP2	CYP4F3;CYP4F2;CYP4F12;CYP4F11	DECR2	GGT5	ALOX5AP	DECR1	ABCC1	
GLUCOCORTICOID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP5280%HOMO SAPIENS	Glucocorticoid biosynthesis	SRD5A2	AKR1D1	HSD11B1	HSD11B2	CYP21A2	CBR1-1	CYP11B1;CYP11B2	SRD5A1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
BENZENE METABOLISM%WIKIPATHWAYS_20260910%WP3891%HOMO SAPIENS	Benzene metabolism	DHDH	NQO1	CYP2E1	MPO	GSTM1;GSTM2-1	EPHX1	
MIR 509 3P ALTERATION OF YAP1 ECM AXIS%WIKIPATHWAYS_20260910%WP3967%HOMO SAPIENS	miR 509 3p alteration of YAP1 ECM axis	COL3A1	COL1A1	YAP1-1	TEAD1	BCAR1	SPARC	TEAD3	TEAD4	GPC6	SNAI2	PBX3	TEAD2	EDNRA	COL5A1	FN1	THBS2	
NUCLEAR RECEPTORS IN LIPID METABOLISM AND TOXICITY%WIKIPATHWAYS_20260910%WP299%HOMO SAPIENS	Nuclear receptors in lipid metabolism and toxicity	CYP27B1	NR1H3	CYP7A1	CYP2B6	CYP4B1	VDR	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	PPARD	ABCC3	ABCD3	CYP26A1	ABCB4	NR1I3	ABCC2	CYP8B1	NR1I2	NR1H4	ABCB11	CYP24A1	ABCG1	ABCA1	ABCG5	RARG	CYP2C9;CYP2C19	ABCD2	RARA	PPARA	RARB	CYP2E1	PPARG	ABCB1	
MALE STEROID HORMONES IN CARDIOMYOCYTE ENERGY METABOLISM%WIKIPATHWAYS_20260910%WP5320%HOMO SAPIENS	Male steroid hormones in cardiomyocyte energy metabolism	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	CYP19A1	SRD5A2	HSD17B2	HSD17B3	CYP17A1	HSD3B1;HSD3B2	CYP11A1	SRD5A1	UGT1A1;UGT1A6	
EPO RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP581%HOMO SAPIENS	EPO receptor signaling	JAK2	RASA1	MAPK3	STAT1	STAT3	IRS1	PTPRC	IRS2	GRB2	SOS1	STAT5A	STAT5B	SHC1-1	SRC	EPO	RAF1	PDK1	EPOR	AKT1	PIK3CG	PTPRU	SOCS1	CISH	MAP2K2;MAP2K1	MAPK1	
PURINE METABOLISM AND RELATED DISORDERS%WIKIPATHWAYS_20260910%WP4224%HOMO SAPIENS	Purine metabolism and related disorders	DGUOK	ITPA	TPMT	MAT2A	ADA	GRM5	PRPS1	ATIC	RRM2B	ADSL	PAICS	IMPDH1	HPRT1	MOCOS	ADSS2	GART	PFAS	PPAT	XDH	PNP-1	AMPD1	APRT	AOX1	
HEMATOPOIETIC STEM CELL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP2849%HOMO SAPIENS	Hematopoietic stem cell differentiation	ITGB3	CSF3	CSF2	TPO	SPI1	VAV1	KLF1	FOS	IL6	TNXB	KCNH2	RHOH	STAT5A	EPO	KITLG	RUNX1	GP9	IL1A	CIITA	IL5	GATA2	MYB	IL3	CSF1	LEF1	ACVR1B	CD34	HES6	IL1B	NOTCH1	NFATC2	CXCR4	MUC1	THRB	LYL1	ITGA2B	IRF5	TRAF3IP3	IKZF1	FOSB	HMGN5	LMO2	TRIM29	PIM1	GATA1	SEC14L2	NCKAP1L	MXI1	NFE2	RIOK3	FLI1	
TCA CYCLE NUTRIENT USE AND INVASIVENESS OF OVARIAN CANCER%WIKIPATHWAYS_20260910%WP2868%HOMO SAPIENS	TCA cycle nutrient use and invasiveness of ovarian cancer	MAPK3	EGFR	JAK1	STAT3	MAPK1	
GUT LIVER INDOLE METABOLISM %WIKIPATHWAYS_20260910%WP3627%HOMO SAPIENS	Gut liver indole metabolism	CYP2E1	
MYOMETRIAL RELAXATION AND CONTRACTION PATHWAYS%WIKIPATHWAYS_20260910%WP289%HOMO SAPIENS	Myometrial relaxation and contraction pathways	ITPR2	ADCY8	ETS2	ATF2	MAFF	ACTG1	FOS	GJA1	ATF5	RYR1	PRKACB-1	PRKAR2B	PRKAR2A	CACNB3	PRKAR1B	PRKAR1A	CREB1	CRHR1	ATF4	YWHAE	GNB5	YWHAB	ACTB-1	YWHAQ	GABPA	YWHAH	ACTA2	ADCY1	SFN	CALM1	CALM2	RYR3	IL1B	PLCB3	ADM	JUN	RGS1	CALM3;CALM1	RGS2	NOS1	GABPB1	GRK6	YWHAG	YWHAZ	ITPR1	NFKB1	ITPR3	CRH	CRCP	RXFP2	RGS4	ATF3	RGS5	RGS3	RGS6	RGS7	IGFBP4	GNG13	CNN2	PLCG2	GRK5	GRK4	PRKCD	CALD1	IGFBP6	PKIB	PKIA	GPR182	GNGT1	PKIG	RGS18	PLCD1	ARRB1	RGS17	RLN2;RLN1	ATP2A3	ARRB2	RAMP2	CNN1	IL6	ATP2A2	RGS19	RAMP3	RGS14	RAMP1	RGS16	RGS20	CORIN	GUCA2B	RGS10	ADCY4	GUCA2A	CALCA	ADCY2	RGS11	RGS9	ADCY7	ADCY6	ATF6B	PDE4B	ADCY5	PDE4D-1	OXT-1	SP1	SLC8A1	ADCY9	GSTO1	IGFBP1	IGFBP3	OXTR	PRKCG	PRKCH	PRKCB	MYL4	MYL2	GNB2	PRKCE	PRKCA	GNB1	LPAR1	GNB4	GNB3	ADCY3	PRKCQ	CAMK2B	PRKD1	RYR2	ACTC1;ACTG2	CAMK2D	PLCG1	CAMK2A	PRKCZ	RXFP1	IGFBP5	CAMK2G	GNAS-1	GNAQ	ACTA1	GUCY1A1	ACKR3-2	MYLK2	GNG2	GNG5	ATF1	GNG4	PRKACA-1	GNG8	NOS3	DGKZ	IGFBP2	CREB3	
INFLAMMATORY RESPONSE PATHWAY%WIKIPATHWAYS_20260910%WP453%HOMO SAPIENS	Inflammatory response pathway	IL2RA	IL2RB	COL1A1	COL1A2	LAMC2	LAMC1	TNFRSF1A	IL5RA	LAMA5	CD40	FN1	THBS3	COL3A1	LCK	IL2	TNFRSF1B	IL4	IFNG	CD40LG	LAMB2	LAMB1	IL5	CD86	CD80	IL2RG	THBS1	VTN	IL4R	CD28	ZAP70	
CYCLIN DEPENDENT KINASE 4 6 INHIBITORS IN BREAST CANCER%WIKIPATHWAYS_20260910%WP5497%HOMO SAPIENS	Cyclin dependent kinase 4 6 inhibitors in breast cancer	CYP19A1	CDK6	MAPK3	CDK4	CDK2	NRAS	PIK3R4	PIK3R3	HRAS	PIK3R6	PIK3R5	CDKN1A	CDKN1B	IRS1	IGF1R	KRAS	INS;INS-IGF2	ESR1	RAF1	CCND1	RPTOR	ERBB2	PIK3CD	AKT2	CCNE1	PIK3C2G	AKT3	PIK3CB	AKT1	PIK3C2A	MTOR	PIK3CG	PIK3C2B	EGFR	PIK3R2	PIK3R1	PIK3CA	MAPK1	
GLIOBLASTOMA SIGNALING%WIKIPATHWAYS_20260910%WP2261%HOMO SAPIENS	Glioblastoma signaling	MAPK3	MAP2K4	PLCG2	ERBB3	PRKCD	GAB1	PDPK1	EP300	RB1	CDKN1A	CDKN1B	IGF1R	BRCA1	CBL	GRB2	CCND2	ERRFI1	FOXO4	SRC	CCND1	ERBB2	PDGFRA	PDGFRB	PTEN	CDKN2B	BRCA2	CCNE1	CDKN2C	TP53	MDM2-2	EGFR	E2F1	MSH6	PRKCG	PRKCI	PRKCH	PRKCB	PRKCA	CDK6	PRKCQ	CDK4	CDK2	NRAS	PLCG1	HRAS	PRKCZ	SPRY2	ATM	NF1	MDM4	MAP2K7	IRS1	KRAS	MAP2K6	MAP2K3	FOXO1-1	RAF1	MET	ARAF	FGFR2	TSC2	FGFR1	FOXO3	PIK3CD	AKT2	PIK3C2G	AKT3	PIK3CB	AKT1	PIK3C2A	PIK3CG	TSC1	PIK3C2B	MAP2K5	CDKN2A	PIK3R2	BRAF	PIK3CA	PIK3R1	MAP2K2;MAP2K1	MAPK1	
PREGNANE X RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2876%HOMO SAPIENS	Pregnane X receptor pathway	DNAJC7	CYP2B6	NCOA1	RXRA	CYP2A13;CYP2A6;CYP2A7-1	PPARGC1A	HSP90AA1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	ABCC3	CYP4F3;CYP4F2;CYP4F12;CYP4F11	ABCC4	ABCC2	NR1I2	FOXO1-1	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	SRPX2	SRC	GSTA3;GSTA5;GSTA1;GSTA2	NRIP1	PSMC5	NCOA2	CYP2C9;CYP2C19	UGT1A1;UGT1A6	NCOA3	SULT2A1-4	ABCB1	
STRIATED MUSCLE CONTRACTION PATHWAY%WIKIPATHWAYS_20260910%WP383%HOMO SAPIENS	Striated muscle contraction pathway	MYL3	MYH6	DMD	DES	TNNI3	ACTC1;ACTG2	TPM4	TPM2	ACTG1	TPM3	ACTA1	ACTN2	ACTN3	MYOM1	TNNI1	ACTN4	TNNI2	MYBPC3	MYBPC1	MYBPC2	TNNC2	NEB	MYH3	VIM	TNNT1	TNNT3	MYH8	TMOD1	TPM1	ACTA2	TNNC1	TTN-1	TCAP	TNNT2	MYL4	MYL2	MYL1	
PROTEOGLYCAN BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP4784%HOMO SAPIENS	Proteoglycan biosynthesis	EXTL3	CSGALNACT1	B3GAT3	SLC35B3	B3GALT6	SLC35B2	EXT1	CHST14	CANT1	EXT2	BPNT2-1	CHSY1-1	B4GALT7	SLC26A2	XYLT2	XYLT1	PAPSS2	CHST3	
SILDENAFIL TREATMENT%WIKIPATHWAYS_20260910%WP5294%HOMO SAPIENS	Sildenafil treatment	NOS2	PDE4B	PDE4A	PDE4D-1	GAPDH-1	NOS1	PRKG1	NOS3	PDE5A	NRF1	PPARGC1A	GUCY1B1	AKT2	PRKN	AKT3	ZNF746	TFAM-1	AKT1	GUCY1A2	GSK3B	GUCY1A1	PDE4C	
SICKLE CELL DISEASE%WIKIPATHWAYS_20260910%WP5604%HOMO SAPIENS	Sickle cell disease	IL18	IL1B	HBA2;HBA1	HBD;HBB	TLR4	
DOPAMINERGIC NEUROGENESIS%WIKIPATHWAYS_20260910%WP2855%HOMO SAPIENS	Dopaminergic neurogenesis	STAT3	RET	WNT1	CDKN1C	SOX2	ALDH1A1	OTX2	GLI1	NR4A2	MSX1	FOXA2	SLC6A3	NEUROD1	EN1	GBX2	LMX1B	NEUROG2	ASCL1	GLI2	SHH	PITX3	TH	NKX6-1	EN2	LMX1A	SLC18A2	DDC	NKX2-2	FGF8	TGFB1	
APOPTOSIS MODULATION BY HSP70%WIKIPATHWAYS_20260910%WP384%HOMO SAPIENS	Apoptosis modulation by HSP70	APAF1	CASP8	FAS	MAPK10	RIPK1	FADD	CYCS-1	TNFRSF1A	HSPA1A;HSPA1B	FASLG	CASP7	CASP9	CASP6	CASP2	BID	MAP3K1	AIFM1	NFKB1	CASP3	
CLEAR CELL RENAL CELL CARCINOMA PATHWAYS%WIKIPATHWAYS_20260910%WP4018%HOMO SAPIENS	Clear cell renal cell carcinoma pathways	PGM2	HK2	LDHA	GAPDH-1	CEP290	SDS	PKM	PGK1	CREBBP	ALDOC	ENO1	HK1	CDH13	PFKM	STAT3	HK3	BAP1	EP300	ENO2	RHEB	ENO3	PFKP	SHMT2	GRB10	VHL	LDHB	SSPN	LDHA;LDHC	ACLY	KDR	PDGFRA	PDGFB	BHLHE41	PDGFRB	CAMK1	PTEN	PKLR	KDM5C	EFCAB3	PLOD2	ENPP3	EGFR	PBRM1	TOX2	RAPGEF5	VEGFA	SDSL	PGBD5	LDHD	SQSTM1	KCNJ2	GPI	SLC2A1	DEPTOR	ALDOA	SHMT1	PHGDH	HIF1A	PGM1	ZEB1	PSPH	PSAT1	ACACA	ACACB	FASN	TPI1	ME1	PFKL	ALDOB	RPTOR	TSC2	MLST8	AKT1	MTOR	TSC1	MAP2K5	KSR1	MDH1	FLT1	ARNT	AKT1S1	SETD2	
UREA CYCLE AND RELATED DISEASES%WIKIPATHWAYS_20260910%WP4571%HOMO SAPIENS	Urea cycle and related diseases	CPS1	GLS2	ASL	NAGS	SLC25A13	OTC	SLC25A15	ARG1	ASS1	
LDLRAD4 INTRONIC SNP EFFECT ON COVID PATIENTS%WIKIPATHWAYS_20260910%WP4904%HOMO SAPIENS	LDLRAD4 intronic SNP effect on COVID patients	SMAD2;SMAD3	NEDD4	ATG16L1	TGFBR1-1	PMEPA1	LDLRAD4	TGFBR2	
5Q35 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5380%HOMO SAPIENS	5q35 copy number variation	MAPK9	TPM2	MAPK10	UIMC1	ABRAXAS1	BRCC3	BRCA1	PNPLA2	MAGED1	INPP5D	ABHD5	SRC	MAX	MYC	GNAI3	GNAI2	ABL1	BARD1	GRIN2B	NTN1	H3-3A	MAPK8	KDM6B	JUN	TMED10	GRIN1	DRD2	PTPN2	TMED2-1	GRK6	PIK3R1	PDLIM7	GAB1	HK3	COX6A1	IGF1R	RGS14	GRB2	SOS1	COX6B1	COX7B	COX4I1	SNCA	COX7C	SLC34A1	COX8A	FGF19	COX5B	COX5A	EIF4E1B	COX6C	B4GALT7	FGF1	NELFB	FBXW7	ADAM10	KIAA1191	ARL10	RNF44	UNC5A	MYO7B	HIC2	GPRIN1	CYP7A1	GNAI1	DOK3	PFN3	PRELID1	PLCG1	PTPRN2	NOP16	HIGD2A	MXD3	PRR7	HIP1	FAF2	DDX41	BABAM1	BABAM2	TMED9	CLTB	ARFGAP2	CDHR2	FAM193B	CDHR5	CXCR4	F12	DBN1	LMAN2	RAB24	ZNF346	SNCB	HIP1R	SIMC1	TSPAN17	NSD1	ANKS4B	FGFR4	EED	CAPN3	FRS2	PTH	USH1C	
COHESIN COMPLEX CORNELIA DE LANGE SYNDROME%WIKIPATHWAYS_20260910%WP5117%HOMO SAPIENS	Cohesin complex Cornelia de Lange syndrome	PDS5B	PDS5A	WAPL	CDK1	PPP2R5B	REC8	PPP2R5A	SMC3	PPP2R5D	AURKB	PPP2CB;PPP2CA	CDCA5	ESCO1	ESCO2	SGO1	PTPA	SMC1A	MAU2	RAD21	PLK1	SGO2	STAG2	HDAC8	PTTG1;PTTG2	PPP2R5E	SMC1B	PPP2R5C	ESPL1	NIPBL	PPP2R1B	PPP2R1A	STAG3	APC	
CANNABINOID RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP3869%HOMO SAPIENS	Cannabinoid receptor signaling	MAPK9	MAPK3	MAPK8	MAPK14	MAPK12	MAPK13	MAPK10	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	MAPK11	FAAH	DAGLA	CYP1A1	CNR1	PRKACB-1	ADCY7	PRKAR2B	PRKACA-1	PRKAR1B	NAPEPLD	PRKAR1A	DAGLB	CYP2C9;CYP2C19	ADORA2A	CNR2	AHR	ADCY1	MAPK1	
CELL LINEAGE MAP FOR NEURONAL DIFFERENTIATION%WIKIPATHWAYS_20260910%WP5417%HOMO SAPIENS	Cell lineage map for neuronal differentiation	DLL1	RIMBP2	GATA6	HES3	ROBO1	SLC6A5	ITGA6	HOMER1	TNC	HNF4A	CNP	SNAP25	CACNG2	AP2A1	HTR1A	AP2A2	MBP	SOX9	PAX3	SOX17	PAX6	SLC18A3	CD34	MOG	CLDN11	UNC13A	GRIN2B	PECAM1	SYP	OLIG2	SOX10	BMP4	GLUL	TPH1	GAD1	SLC1A3	GAD2	SLC6A9	LHX1	SLC17A6	SLC17A7	SOX2	TUBB3;TUBB6	MSX2	ESRRB	ACHE	NR4A2	NEFL	SLC6A1	FOXA2	CDH1	SLC6A2	SLC6A3	GRIN1	SLC6A4	FOXD3	SHANK3	TH	CHAT	NLGN1	KLF4	DPPA3	NGFR	FABP7	NEFM	GATA4	KCNJ6	CDH2	SNAI1	SNAI2	SLC1A2	MSX1	FEV	GFAP	ADRA2C	HTR5A	ADRA2B	ADRA2A	MAP2	FGF4	LEF1	TPM1	HES1	GPHN	HES5	ZFP42	GABBR2	POU5F1;POU5F1B	ALDH1L1	GABBR1	TBXT	GLS	CASK	NOTCH1	NANOG;NANOGP8	MIXL1	NODAL	DLG1	DLG2	SHANK1	DLG4	DCX	LMX1B	RIMS2	PPFIA1	HOMER3	BSN	RBFOX3	FBXO15	TBR1	TWIST2	LIN7A	FUT4	HOMER2	EVX1	DLG3	CD24	NES	PCLO	CSPG4	ERC1	DPPA2	ERAS	GLRA1	ITGB1	GLRA2	AQP4	GLRA3	GLRB	KRT15	
GPCRS CLASS C METABOTROPIC GLUTAMATE PHEROMONE%WIKIPATHWAYS_20260910%WP501%HOMO SAPIENS	GPCRs class C metabotropic glutamate pheromone	CASR	GABBR1	GPRC5B	GPRC5A	GPRC5D	GPRC5C	GRM3	GRM6	GRM5	GRM1	GRM2	GRM4	GRM7	GRM8	GABBR2	
GLYCOGEN SYNTHESIS AND DEGRADATION%WIKIPATHWAYS_20260910%WP500%HOMO SAPIENS	Glycogen synthesis and degradation	HK2	PYGB	GBE1	UGP2	PYGM	PYGL	PHKG1	HK1	GYG2	PGM1	PHKB	PHKA1	GYS2	HK3	HKDC1	AGL-1	GYS1	PPP2R5B	PPP2R5A	PPP2R5D	PPP2CB;PPP2CA	CALM3;CALM1	PPP2R3B	PTPA	PPP2R3A	PPP2R2C	PHKG2	PPP2R2B	PPP2R5E	GYG1	PPP2R5C	GSK3B	GSK3A	PPP2R1B	PPP2R1A	PHKA2	CALM1	PPP2R2A;PPP2R2D	CALM2	
HIF1A AND PPARG IN HYPERTROPHIC CARDIOMYOPATHY%WIKIPATHWAYS_20260910%WP2456%HOMO SAPIENS	HIF1A and PPARG in hypertrophic cardiomyopathy	SLC2A1	LDHA	GAPDH-1	GPD1	HIF1A	CD36	GPAT3	PPARG	TPI1	
PATHOGENIC ESCHERICHIA COLI INFECTION%WIKIPATHWAYS_20260910%WP2272%HOMO SAPIENS	Pathogenic Escherichia coli infection	PRKCA	TUBA1C	NCK2	EZR	TUBA1A	WAS	LY96	CD14	TUBA3E;TUBA3C-1	CTTN	ARPC5L	TUBB4A;TUBB;TUBB8B;TUBB8	ARPC1A	CTNNB1	ARPC4	RHOA	KRT18	TUBA8	ACTG1	ARPC2	ARPC3	ARHGEF2	TUBB3;TUBB6	TUBB2B;TUBB2A	ARPC5	CLDN1	NCK1	ROCK1	TUBAL3	ROCK2	CDC42	TUBB4B	CDH1	NCL-1	TLR5	ARPC1B	FYN	TLR4	TUBB1	HCLS1	YWHAQ	ACTB-1	TUBA4A	ABL1	OCLN-1	YWHAZ	ITGB1	WASL	
COMPLEMENT MEDIATED INFLAMMATION OF PULMONARY ALVEOLUS IN COVID 19 HYPOTHETICAL PATHWAY %WIKIPATHWAYS_20260910%WP5148%HOMO SAPIENS	Complement mediated inflammation of pulmonary alveolus in COVID 19 hypothetical pathway	C3-1	C8A	ACE2	C3AR1	FCN2;FCN1	COLEC11	C5AR1	C6	C7	C9	MASP2	C5	
CHOLESTASIS%WIKIPATHWAYS_20260910%WP5238%HOMO SAPIENS	Cholestasis	TJP2	SCARB1	RXRA	EPHX1	ABCC3	HMGCR	SLCO1A2	ABCC4	SLC10A1	ABCB4	ABCC2	ATP8B1	NR1I3	SLC22A1	NR1H4	ABCB11	ABCG8	LDLR	ABCG5	
17Q12 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5287%HOMO SAPIENS	17q12 copy number variation syndrome	DUSP14	TEC	DHRS11	SLC35G4;SLC35G5;SLC35G3;SLC35G6	CWC25	SLFN11;SLFN13	AATF	CCL3L1;CCL3L3;CCL3;CCL18	IKZF3	CISD3	RDM1	CCL11	LASP1	ARL5C	C17orf98	CACNB1	C17orf50	CCL4L2;CCL4L1;CCL4	GPR179	UNC45B	ERBB2	DDX52	LYZL6-1	MRPL45	PPP1R1B	SRCIN1	RAD51D	SLFN14	ZNF830	CCL14	CCL1	STARD3	SLFN5	GGNBP2	CCL8	TMEM132E	FBXO47	MLLT6	HNF1B	FBXL20	CCT6B	NEUROD2	MIEN1	ZNHIT3	PNMT	C17orf78	RFFL	LIG3	ASIC2	SOCS7	GAS2L2	CCL16	HEATR9	TAF15	TCAP	RASL10B	SYNRG	PCGF2	EPOP	PEX12	AP2B1	MYO19	FNDC8	PLXDC1	GRB7	NLE1	ARHGAP23	TADA2A	STAC2	RPL23	SLFN12L;SLFN12-1	CDK12	LHX1	MED1	PGAP3	MMP28	PIGW	ACACA	CCL23;CCL15	CCL5	CCL13;CCL2	PIP4K2B	
MOLYBDENUM COFACTOR MOCO BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP4507%HOMO SAPIENS	Molybdenum cofactor Moco biosynthesis	SUOX	MOCS2	GPHN	MTARC2	XDH	MOCS1	AOX1	
VOLTAGE GATED SODIUM CHANNEL ACTION POTENTIAL%WIKIPATHWAYS_20260910%WP5594%HOMO SAPIENS	Voltage gated sodium channel action potential	PRKCA	PRKACA-1	AKAP7	
EFFECT OF PROGERIN ON GENES INVOLVED IN PROGERIA%WIKIPATHWAYS_20260910%WP4320%HOMO SAPIENS	Effect of progerin on genes involved in progeria	H3-3A	HDAC2	SUV39H1	MTA1	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	MTA3	CBX1	CHD4	CHD3	TP53	RB1	SREBF1	LEF1	E2F1	HDAC1	CBX3-1	INPP5K	MTA2	MBD3	MBD2	RBBP7	RBBP4	KDM1A	CBX5	
MRNA VACCINE ACTIVATION OF DENDRITIC CELL AND INDUCTION OF IFN 1%WIKIPATHWAYS_20260910%WP5187%HOMO SAPIENS	mRNA vaccine activation of dendritic cell and induction of IFN 1	IRF3	TNFRSF11A	IFIH1	MAVS	IRF7	TLR8	TLR7	MR1	TLR3	DDX58	
METABOLIC EPILEPTIC DISORDERS%WIKIPATHWAYS_20260910%WP5355%HOMO SAPIENS	Metabolic epileptic disorders	GATM	PC	HLCS	CPS1	HK2	LDHA	ASL	GAPDH-1	ECHS1	PKM	OTC	PGK1	ALDOC	ENO1	HK1	PFKM	ACAT1	HK3	SLC2A5	CBS;CBSL	GCDH	ENO2	ENO3	MPC2	PFKP	DLD	FBP2	SHMT2	LDHAL6B	SLC25A5	SLC25A1	GPT	DHTKD1	LDHB	PDHA1	LDHA;LDHC	MPC1	CTH	PKLR	MDH2	GOT2-1	AADAT	GPHN	ALDH7A1	XDH	SLC25A15	GPI	GOT1-1	SLC2A1	HADH	ALDOA	SLC1A5	GLS2	SHMT1	PGAM1	PHGDH	MOCS2	SLC2A2	MOCS1	PSPH	CDO1	MOCS3	AMT	AASS	SQOR	SLC7A2	SUOX	ETHE1	SPCS1	GCK	GLUD1;GLUD2	DLAT	GLDC	PSAT1	TPI1	PCK1	SLC2A4	PFKL	ALDOB	ACO1	FBP1	SFXN1	PGAM2	G6PC1	MDH1	GAMT	ARG1	BTD	ASS1	
SARS COV 2 AND COVID 19 PATHWAY%WIKIPATHWAYS_20260910%WP4846%HOMO SAPIENS	SARS CoV 2 and COVID 19 pathway	NRP1	ACE2	TMPRSS2	TMPRSS4	FURIN	SCARB1	TLR7	CTSV;CTSL	SLC6A19	ACAT1	
REGULATION OF WNT B CATENIN SIGNALING BY SMALL MOLECULE COMPOUNDS%WIKIPATHWAYS_20260910%WP3664%HOMO SAPIENS	Regulation of Wnt B catenin signaling by small molecule compounds	DVL2	TCF4	FZD8	FZD1	TNKS	CTNNB1	WNT1	AXIN1	MBOAT1	LEF1	DKK3	GSK3B	SFRP4	LRP1	FZD7	CSNK1A1	APC	
MICRORNAS IN CARDIOMYOCYTE HYPERTROPHY%WIKIPATHWAYS_20260910%WP1544%HOMO SAPIENS	MicroRNAs in cardiomyocyte hypertrophy	MAPK3	MAPK7	PRKG1	MAP2K4	MAPK4	MAPK14	STAT3	IKBKB	PDPK1	GATA4	AGT	CTNNB1	IKBKG	CHUK	EDN1	IGF1R	IL6ST	EGF	ROCK1	ROCK2	DVL1	MYLK	FGF2	TNF	HDAC4	HDAC5	HDAC9	HDAC7	MYLK3	LIF	NRG1	IGF1	NFATC4	CDK9	CALM1	PRKCB	TAB1	MAP3K14	PPP3CA	PPP3CB	PLA2G2A-1	CAMK2D	CTF1	MAPK8	PIK3R3	CDK7	NPPA	RHOA	PLCB2	MAP2K7	MAP2K6	MAP2K3	EIF2B5	FZD2	RAF1	FZD1	NPPB	WNT3A	WNT5A	FGFR2	LRP6	PIK3CD	AKT2	PIK3CB	AKT1	MTOR	PIK3CG	MYEF2	MAP2K5	GSK3B	CISH	PIK3R2	PIK3CA	PIK3R1	TGFB1	RCAN1	IKBKE	LRP5	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	
COVID 19 THROMBOSIS AND ANTICOAGULATION%WIKIPATHWAYS_20260910%WP4927%HOMO SAPIENS	COVID 19 thrombosis and anticoagulation	FGB	FGA	F13B	FGG	F13A1	F2	PLG	
IL26 SIGNALING%WIKIPATHWAYS_20260910%WP5347%HOMO SAPIENS	IL26 signaling	JAK2	MAPK9	IL1B	MAPK3	JAK1	EPHA3	CSF2	MAPK8	STAT1	MPO	MAPK14	BAX	ICAM1	STAT3	TYK2	MMP1	DEFB4A;DEFB4B	IL20RA	IL6	DCSTAMP	RELA	TNFSF11	RORC	JUN	MMP9	NFKBIA	DDIT3	CASP3	IL10	CXCL8	SMAD2;SMAD3	NFATC1	IL26	ATP6V0D2	TNF	IL33	CCL20	AKT1	IL10RB	ACTA2	PIK3CA	SOCS3	MAPK1	IL17A	CTSK	
SULFATION BIOTRANSFORMATION REACTION%WIKIPATHWAYS_20260910%WP692%HOMO SAPIENS	Sulfation biotransformation reaction	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	SULT4A1	SULT2B1	G6PD	SULT1B1-1	PAPSS1	SULT6B1	GSR	SULT2A1-4	SULT1C3	PAPSS2	SULT1C2	
NSAIDS MECHANISM OF ACTION%WIKIPATHWAYS_20260910%WP5513%HOMO SAPIENS	NSAIDs mechanism of action	PTGS1	PTGS2-2	
LEPTIN SIGNALING%WIKIPATHWAYS_20260910%WP2034%HOMO SAPIENS	Leptin signaling	JAK2	SOCS2	EIF4EBP1	PTPN1	MAPK3	JAK1	NCOA1	PRKAA1	PLCG2	STAT1	BAD	MAPK14	STAT3	ELK1	IKBKB	PTPN11	LEP	IKBKG	CHUK	RPS6KB1	RELA	GRB2	PRKAA2	SOS1	STAT5B	SHC1-1	ROCK1	ROCK2	ESR1	SRC	CDC42	PDE3B	ERBB2	SP1	CREB1	PTEN	KHDRBS1	SOCS7	GSK3A	MAPK8	PLCG1	HRAS	RHOA	RPS6KA1	IRS1	EIF4E	LEPR	FOXO1-1	KPNA4-1	ACACA	ACACB	CFL2	RAF1	NOS3	SH2B1	FYN	AKT1	MTOR	REL	GSK3B	CISH	RPS6	PIK3R2	PIK3R1	PTK2	SOCS3	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	
MALATE ASPARTATE SHUTTLE%WIKIPATHWAYS_20260910%WP4315%HOMO SAPIENS	Malate aspartate shuttle	MDH1	GOT2-1	SLC1A3	SLC25A11	
ALTERNATIVE PATHWAY OF FETAL ANDROGEN SYNTHESIS%WIKIPATHWAYS_20260910%WP4524%HOMO SAPIENS	Alternative pathway of fetal androgen synthesis	CYB5A	STAR	SRD5A2	HSD17B3	CYP17A1	POR	HSD3B1;HSD3B2	CYP11A1	HSD17B6	
REGULATORY CIRCUITS OF STAT3 SIGNALING%WIKIPATHWAYS_20260910%WP4538%HOMO SAPIENS	Regulatory circuits of STAT3 signaling	JAK2	IL6R	IL2RA	MAPK9	IL2RB	MAPK3	F2RL3	JAK1	MAPK7	MAPK6	CREBBP	MAPK4	MAPK14	STAT3	MAPK12	MAPK13	MAPK10	TYK2	MAPK11	JAK3	IL20RA	OSMR	IL20RB	CNTFR	PTPRC	IL27RA	IL5RA	IL6ST	CSF2RB	IFNLR1	SRC	IL22RA1	CSF3R	PDGFRA	MAPKAP1	F2R	PDGFRB	CSF2RA	IL10RB	EGFR	RICTOR	MPL	PRKCB	DEPTOR	IL7R	IL9R	CTF1	MAPK8	IL11RA	GHR	DUSP2	IL3RA	PTPRT	MAPK15	PTPRD	SETD7	STMN1	IL21R	RPTOR	IL12RB2	IFNGR1	IFNAR2	TRIM28	IFNGR2	MLST8	MTOR	F2RL2	LIFR	IFNAR1	AGTR1	IL2RG	AGTR2	PIAS3	AKT1S1	SOCS3	IL10RA	MAPK1	
OVERVIEW OF PROINFLAMMATORY AND PROFIBROTIC MEDIATORS%WIKIPATHWAYS_20260910%WP5095%HOMO SAPIENS	Overview of proinflammatory and profibrotic mediators	IFNK	CCL27	IL19	CCL26	IL36A	IL36B	XCL1;XCL2	EBI3	IL36G	AREG	EPO	IL1F10	IL20	PF4;PF4V1-1	IL26	IL27	CNTF	CCL14	CCL1	TNF	IL11	CCL8	IL33	CXCL13	IFNB1-4	CCL20	IL15	CCL25	IL3	CCL24	IL31	IL7	IL37	LIF	CCL19	CCL16	CXCL2;CXCL3;CXCL1-1	CCL21	CXCL11	IL36RN	IL1B	CCL17	CCL22	LTA	CX3CL1	CCL23;CCL15	MMP3	CCL5	TSLP	CCL13;CCL2	IL17D	TGFB1	IL17C	IL17B	NFKB1	CXCL10	CSF3	CSF2	IL12B	MMP1	TNFSF13B	IL6	IL13	CCL28	MMP9	CCL3L1;CCL3L3;CCL3;CCL18	IFNL2;IFNL3;IFNL1	IL10	OSM	CCL11	CXCL8	IL18	CCL4L2;CCL4L1;CCL4	IL2	IL9	IL4	SPP1	IL1A	IFNG	IL12A	IL5	CXCL14	CXCL9	CSF1	CXCL17	VEGFA	IL17F	PPBP	IL17A	IL24	CTF1	IL1RN	IL21	IL22	CXCL12	IL25	IL23A	CXCL5;CXCL6	
ATM SIGNALING IN DEVELOPMENT AND DISEASE %WIKIPATHWAYS_20260910%WP3878%HOMO SAPIENS	ATM signaling in development and disease	RAD50	NHEJ1	CDK5	RNF168-1	CDK2	RNF8	PRKDC	MAPK14	ATF2	MAPK12	MAPK13	ATM	ATR	MDC1	MAPK11	TP53BP1	IKBKG	MRE11	G6PD	PPM1D	RBBP8	AURKB	CHEK2	PPP2CB;PPP2CA	RNF20	ATMIN-1	CHEK1	RNF40	CEP63	NBN	STK11	SMC1A	TRIM28	CDC25A	TSC2	HDAC4	DCLRE1C	TP53	MTOR	HSPB1	PPP5C	HMGN1	BUB1	LMNB2	NFKB1	RIF1	KAT5	
VITAMIN A1 AND A5 X PATHWAYS%WIKIPATHWAYS_20260910%WP5397%HOMO SAPIENS	Vitamin A1 and A5 X pathways	RXRG	RARA	RARB	RARG	RXRA	RXRB	
IRON METABOLISM DISORDERS%WIKIPATHWAYS_20260910%WP5172%HOMO SAPIENS	Iron metabolism disorders	CYBRD1	HEPH	TFR2	FTL-1	TFRC	HFE	SLC11A2	TF	SLC40A1	FTH1	BCS1L	HJV	STEAP3	HAMP	CP	UQCRFS1	
OXIDATIVE STRESS RESPONSE%WIKIPATHWAYS_20260910%WP408%HOMO SAPIENS	Oxidative stress response	TXNRD2	JUNB	TXNRD1	MAPK14	MAPK10	FOS	CYP1A1	GPX1	GSR	GSTT2B;GSTT2	TXN2	GCLC	NFIX	SOD2	SOD3	NOX3	HMOX1	NQO1	SOD1	NOX5	SP1	UGT1A1;UGT1A6	NFE2L2	CYBB	MAOA	CAT	XDH	NOX4	NFKB1	MGST1	NOX1	
THYMIC STROMAL LYMPHOPOIETIN TSLP SIGNALING%WIKIPATHWAYS_20260910%WP2203%HOMO SAPIENS	Thymic stromal lymphopoietin TSLP signaling	JAK2	EIF4EBP1	MAPK9	TEC	IL7R	MAPK3	JAK1	MAPK8	STAT1	MAPK14	STAT3	YES1	PTPN11	GAB2	HCK	RELA	LYN	STAT5A	STAT5B	NFKBIA	BTK	FES	SRC	STAT4	LCK	FYN	TSLP	AKT1	CRLF2	STAT6	RELB	RPS6	MAP2K2;MAP2K1	NFKB1	MAPK1	NFKB2	
DRAVET SYNDROME%WIKIPATHWAYS_20260910%WP5200%HOMO SAPIENS	Dravet syndrome	PRKCA	FGF13	STXBP1	SCN3B	SCN3A	SCN1B	CAMK2A	SCN4B	SCN2B	MAPK11	PRR5	PRR5L	HCN1	SCN1A	KCNA2	PCDH19	MAPKAP1	SCN2A	MLST8	SCN8A	TNF	AKT1	SNTA1	MTOR	RICTOR	PIK3CA	CHD2	NFKB1	CALM1	
IMMUNE INFILTRATION IN PANCREATIC CANCER%WIKIPATHWAYS_20260910%WP5285%HOMO SAPIENS	Immune infiltration in pancreatic cancer	IL1B	CSF2	IL12B	IL6	LGALS3	LGALS1	IL13	CCL28	CXCL12	MMP9	VEGFB	IL10	IL25	VEGFD	CXCL8	IL2	LGALS9C;LGALS9;LGALS9B	IL4	IFNG	IL23A	CCL5	REG4	IL12A	TNF	IL5	CCL20	CCL13;CCL2	VEGFC	TGFB2	VEGFA	IL17D	TGFB1	CXCL2;CXCL3;CXCL1-1	IL17C	TGFB3	IL17F	CXCL5;CXCL6	IL17B	IL17A	
PRO SURVIVAL SIGNALING OF NEUROPROTECTIN D1%WIKIPATHWAYS_20260910%WP5182%HOMO SAPIENS	Pro survival signaling of neuroprotectin D1	BIRC3	CASP8	RIPK3	BAX	TRADD	TNF	RIPK1	FADD	CYCS-1	TNFRSF1A	CASP7	TRAF2	CASP9	PPP2CB;PPP2CA	CASP3	
FACT COMPLEX AND DNA DOUBLE STRAND BREAK REPAIR%WIKIPATHWAYS_20260910%WP5564%HOMO SAPIENS	FACT complex and DNA double strand break repair	H4C6	NBN	RAD51	RNF168-1	RNF8	PRKDC	RAD54L	ATM	MDC1	NASP-1	TP53BP1	SUPT16H	XRCC6	XRCC5	H4-16	NAP1L1	SSRP1	SETD2	H4C1	
AUTOPHAGY%WIKIPATHWAYS_20260910%WP4923%HOMO SAPIENS	Autophagy	UVRAG	DEPTOR	ATG16L1	PRKAA1	ATG101	PIK3R4	ATG9A	RB1CC1	PRKAA2	PRKAG1	WIPI2	PRKAG2	BECN1	PRKAG3	AMBRA1	PRKAB2	RPTOR	ATG14	PRKAB1	ATG13	MLST8	ULK1	MTOR	ATG3	MAP1LC3B2;MAP1LC3B-1	ATG12-1	AKT1S1	PIK3C3	ATG7	ATG5	
SULFATASE AND AROMATASE PATHWAY%WIKIPATHWAYS_20260910%WP5368%HOMO SAPIENS	Sulfatase and aromatase pathway	SLCO4A1	HSD17B1	SLCO1A2	CYP19A1	HSD17B2	HSD17B3	ESR2	HSD3B1;HSD3B2	SLCO2B1	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	SLCO4C1	ESR1	
COMPLEMENT ACTIVATION%WIKIPATHWAYS_20260910%WP545%HOMO SAPIENS	Complement activation	C1QB	C3-1	C1S	CFP	C1QC	C1R	C2	C6	C7	C9	CD55	C8B	C8A	C8G	LOC110384692;C4A;C4B_2;C4B	MASP2	C5	MASP1	CFB	CFD	
PENTOSE PHOSPHATE PATHWAY IN SENESCENT CELLS%WIKIPATHWAYS_20260910%WP5043%HOMO SAPIENS	Pentose phosphate pathway in senescent cells	RPIA	TALDO1	RPE;RPEL1	G6PD	PGLS	DERA	TP53	
SMALL CELL LUNG CANCER%WIKIPATHWAYS_20260910%WP4658%HOMO SAPIENS	Small cell lung cancer	TRAF6	NFKBIB	RXRA	ITGAV	IKBKB	ITGA3	ITGA2	RB1	IKBKG	CHUK	CDKN1A	CDKN1B	CDKN1C	ITGA6	RELA	CASP9	SKP1	TRAF2	BCL2L1	NFKBIA	CASP3	FN1	MAX	CCND1	MYC	NOS2	APAF1	TRAF4	BIRC7	BIRC2	BIRC3	ZBTB17	DDB2	CCNE2	COL4A2	PTEN	COL4A1	CDKN2B	CCNE1	POLK	COL4A4	COL4A6	TP53	CKS1B	FHIT	CYCS-1	E2F1	E2F2	LAMB4	E2F3	BAK1	BID	GADD45B	GADD45A	GADD45G	CDK6	CDK4	CDK2	LAMC3	LAMC2	CASP8	LAMC1	PIK3R3	BAX	TRAF5	TRAF1	PTGS2-2	LAMA5	LAMA2	TRAF3	LAMA1	LAMA4	LAMA3	RXRB	BCL2	ITGA2B	RXRG	COL4A3	COL4A5	LAMB3	LAMB2	LAMB1	PIK3CD	AKT2	CKS2	AKT3	PIK3CB	AKT1	RARB	PIK3R2	PIK3CA	PIK3R1	PTK2	ITGB1	NFKB1	
ISOGLOBO SERIES SPHINGOLIPIDS%WIKIPATHWAYS_20260910%WP5311%HOMO SAPIENS	Isoglobo series sphingolipids	B3GALT5	
IL3 SIGNALING%WIKIPATHWAYS_20260910%WP286%HOMO SAPIENS	IL3 signaling	JAK2	MAPK3	JAK1	BAD	STAT3	PTPN11	CCR3	VAV1	GAB2	FOS	HCK	RAPGEF1	CBL	GRB2	IL5RA	INPP5D	CSF2RB	SOS1	LYN	SYK	STAT5A	STAT5B	BCL2L1	SHC1-1	PTPN6	CXCL8	SRC	YWHAB	YWHAQ	IL3	ENPP3	MAPK8	HRAS	IL3RA	JUN	CRKL	BCL2	RAF1	PRKACA-1	FYN	CD69	PIK3CD	CD86	AKT1	PIK3R2	PIK3R1	TGFB1	MAP2K2;MAP2K1	MAPK1	
PHOTODYNAMIC THERAPY INDUCED AP 1 SURVIVAL SIGNALING%WIKIPATHWAYS_20260910%WP3611%HOMO SAPIENS	Photodynamic therapy induced AP 1 survival signaling	TRAF6	JUNB	MAP2K4	HBEGF	MAPK14	ATF2	MAPK12	ELK1	MAPK13	MAPK11	RB1	CDKN1A	FOS	IL6	MMP2	TRAF2	BCL2L1	CCND1	IL2	IFNG	PDGFRA	CFLAR	TNF	CCNE1	BMF	TP53	NFE2L2	CCNA2-1	EGFR	FGF7	BAK1	BID	MCL1	MAPK8	FAS	BAX	HSP90AA1	TNFRSF1A	MAP2K7	TRAF5	MAP2K6	MAP2K3	JUN	BCL2	BCL3	BCL2L11	MAP3K5	FASLG	CDKN2A	TNFSF10	
NRP1 TRIGGERED SIGNALING IN PANCREATIC CANCER %WIKIPATHWAYS_20260910%WP5144%HOMO SAPIENS	NRP1 triggered signaling in pancreatic cancer	NRP1	CDH5	MAPK3	COL1A1	COL1A2	PLXNA1	PLXNA2	CCN2	CDKN1B	HGF	SNAI1	SNAI2	MMP2	RELA	MMP9	EGF	SRC	CHD1	KDR	CCNE2	BCAR1	CCNE1	SLC39A4	EGFR	RELB	VEGFA	PECAM1	GSK3A	CHD2	CDK2	SEMA3A	SMAD4	TGFBR1-1	MET	SMAD2;SMAD3	AKT2	AKT3	AKT1	TGFBR3	PLXNA4	REL	TGFB2	PTK2	FLT1	TGFB3	MAP2K2;MAP2K1	NFKB1	MAPK1	NFKB2	RAC1	TGFBR2	
PEPTIDE GPCRS%WIKIPATHWAYS_20260910%WP24%HOMO SAPIENS	Peptide GPCRs	MC5R	OPRL1	CCR9	TACR3	GHSR	NPY1R	HCRTR2	HCRTR1	CCR3	CCR2	TSHR	C3AR1	TACR1	OPRK1	NPY5R	CCR8	CCR6	AVPR2	SSTR2	OPRM1	C5AR1	SSTR1	SSTR3	CX3CR1	SSTR4	SSTR5	CXCR6	MC3R	OXTR	CXCR5	GRPR	EDNRA	LHCGR	EDNRB	TRHR	FSHR	FPR1	MC2R	GALR3	GALR2	GALR1	CCR10	NTSR1	NPY2R	NTSR2	CCR1	NMBR	GNRHR	MC1R	CXCR4	BDKRB2	NPY4R2;NPY4R	BRS3	MC4R	CCKAR	CCR7	CCR5	CCR4	AVPR1B	FPR2	ACKR1	BDKRB1	AVPR1A	ATP8A1	CCKBR	TACR2	TAC4	AGTR1	AGTR2	OPRD1	CXCR1	CXCR3	CXCR2	
PATHOPHYSIOLOGICAL ROLES OF DUX4 IN FSHD1%WIKIPATHWAYS_20260910%WP5342%HOMO SAPIENS	Pathophysiological roles of DUX4 in FSHD1	ADRB2	MYC	ESR2	PAX7	FBXO32	UPF1	PPARGC1A	RET	EP300	CDKN1A	TRIM63	DUX4;DUXA	MYF5	VEGFA	MYOD1	MYOG	
CAFFEINE IN MYOCYTES%WIKIPATHWAYS_20260910%WP5603%HOMO SAPIENS	Caffeine in myocytes	MYL3	MYH6	RYR3	RYR2	TNNI3	ACTC1;ACTG2	TPM4	TPM2	ACTG1	TPM3	RYR1	ACTA1	MYH11	TNNI1	TNNI2	TNNC2	MYH3	TNNT1	TNNT3	MYH8	MYLPF	MYL6	ACTB-1	MYH13	TPM1	ACTA2	MYH1	TNNC1	MYH7	TNNT2	MYL2	MYL1	
MEVALONATE PATHWAY%WIKIPATHWAYS_20260910%WP3963%HOMO SAPIENS	Mevalonate pathway	MVD	HMGCS1-1	HMGCR	PMVK	FDPS	MVK	ACAT2	
CHOLESTEROL METABOLISM WITH BLOCH AND KANDUTSCH RUSSELL PATHWAYS%WIKIPATHWAYS_20260910%WP4718%HOMO SAPIENS	Cholesterol metabolism with Bloch and Kandutsch Russell pathways	NR1H3	IDI1	EBP	CYP51A1	MVK	NSDHL	SC5D	MSMO1	DHCR24	HSD17B7	DHCR7	ACAT2	LBR	TM7SF2	HMGCS1-1	PMVK	SREBF1	ACOT2;ACOT1	FDFT1	MYLIP	FDPS	GGPS1	NR1H2	ELOVL3	ACSL3	LSS	FASN	CH25H	ABCG1	ABCA1	HMGCS2	SQLE	SOAT1	CYP46A1	SREBF2	FADS2	ACSL1	SCD	FADS1	SOAT2	ELOVL4	MVD	HMGCR	ELOVL2	ELOVL5	CYP27A1	ACSL4	
TP53 NETWORK%WIKIPATHWAYS_20260910%WP1742%HOMO SAPIENS	TP53 network	MYC	BOK	BAX	ATM	TP53	MDM2-2	CDKN1A	TP73	ABL1	TP63	OTX2	CDKN2A	BBC3	PMAIP1	BID	TNFSF10	GADD45A	BCL2	SUMO1	
AUTOSOMAL RECESSIVE OSTEOPETROSIS PATHWAYS%WIKIPATHWAYS_20260910%WP4788%HOMO SAPIENS	Autosomal recessive osteopetrosis pathways	TRAF6	PLEKHM1	TNFRSF11A	TNFSF11	CLCN7	OSTM1	SNX10	TCIRG1	NFKB1	RAB7A	IKBKB	
RENIN ANGIOTENSIN SYSTEM AND BRADYKININ PATHWAYS IN COVID 19%WIKIPATHWAYS_20260910%WP4969%HOMO SAPIENS	Renin Angiotensin System and Bradykinin pathways in COVID 19	NPR1	IL1B	KNG1	PRKG1	SERPINE1	REN	VDR	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	AGT	RHOA	F12	BDKRB2	SERPING1	KLKB1	CPN1	CYP24A1	ROCK1	NOS1	IL1A	KLK1	NOS3	TNF	BDKRB1	ACE2	ACE	AGTR1	AGTR2	NFKB1	MAPK1	
KETOGENESIS AND KETOLYSIS%WIKIPATHWAYS_20260910%WP4742%HOMO SAPIENS	Ketogenesis and ketolysis	SLC2A1	UCP2	BDH1	OXCT1-1	SLC16A1	ACAT1	CPT2	SLC25A20	
HINT1 PATHWAY%WIKIPATHWAYS_20260910%WP5523%HOMO SAPIENS	HINT1 pathway	TCF4	ERCC3	MAPK9	GTF2H2C;GTF2H2C_2;GTF2H2	ERCC2	RUVBL1	CDK7	MNAT1	CCNH	NFATC2	SH3RF1	CTNNB1	FOS	JUN	KARS1	GTF2H1	GTF2H3	USF2	MITF	NFKB1	HINT1	GTF2H4	RUVBL2	
EFFECT OF DASATINIB ON THE BCR ABL SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP5493%HOMO SAPIENS	Effect of dasatinib on the BCR ABL signaling pathway	BCLAF1	MAPK3	NRAS	MAP3K2	MAPK14	ATF2	HRAS	MAPK11	VAV1	RPS6KA1	GAB2	SPAG1	CBL	KRAS	GRB2	INPP5D	SOS1	CRK	SHC4	CRKL	SHC1-1	SHC2	BCL2	DOK1	SRC	RAF1	ARAF	EIF4B	BCAR1	AKT2	AKT3	SHC3	AKT1	PXN	HSPB1	ABL1	BCR	BRAF	PIK3R1	PTK2	PIK3CA	MEF2C	MAPK1	HSPB2	BCL9	
GPR143 IN MELANOCYTES AND RETINAL PIGMENT EPITHELIUM CELLS%WIKIPATHWAYS_20260910%WP4941%HOMO SAPIENS	GPR143 in melanocytes and retinal pigment epithelium cells	PMEL	TYRP1	ASIP	MLANA	PLCB3	PLCB4	GNAS-1	ARRB1	POMC	GNAQ	ARRB2	PLCB1	MC1R	PLCB2	ADCY4	ADCY2	MITF	PRKACB-1	GNA15	TYR	PRKACA-1	DCT	CREB1	GPR143	ADCY9	SERPINF1	VEGFA	ITPR1	PRKCB	
IRINOTECAN PATHWAY%WIKIPATHWAYS_20260910%WP229%HOMO SAPIENS	Irinotecan pathway	ABCC2	CES2	BCHE	ABCG2	CES1	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	ABCC1	UGT1A1;UGT1A6	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
GDNF RET SIGNALING AXIS%WIKIPATHWAYS_20260910%WP4830%HOMO SAPIENS	GDNF RET signaling axis	EYA1	BMP4	GDNF	WT1	ROBO1	LHX1	HOXC11	FOXC2	FOXC1	FAT4	RET	GFRA1	SOX11	CTNNB1	GREM1	HSPB11	SALL1	SIX2	IFT27	GATA3	HNF1B	ROBO2	GLI3	HOXD11	SOX17	HOXA11	PAX2	AGTR2	SLIT2	ALDH1A2	SPRY1	
HSPB3 IN CHARCOT MARIE TOOTH DISEASE%WIKIPATHWAYS_20260910%WP5524%HOMO SAPIENS	HSPB3 in Charcot Marie Tooth disease	H2AZ2;H2AZ1	DES	NOTCH3	DMPK	LMNA	HP1BP3	HSPB3	LBR	LMNB1	ACTA1	MEF2C	MYOD1	MYOG	CBX5	HSPB2	
CELL INTERACTIONS IN PANCREATIC CANCER MICROENVIRONMENT%WIKIPATHWAYS_20260910%WP5284%HOMO SAPIENS	Cell interactions in pancreatic cancer microenvironment	NRP1	CXCL10	CSF2	FAS	ITGB6	CCR2	CXCR4	CXCL12	IFITM3;IFITM2;IFITM1	CCR5	KDR	CCL5	CSF2RA	BAG3	CD86	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	CSF1R	CCL13;CCL2	CSF1	CD80	FASLG	HLA-DRA	CTLA4	CXCR3	VEGFA	TGFB1	LAG3	
ACE INHIBITOR PATHWAY%WIKIPATHWAYS_20260910%WP554%HOMO SAPIENS	ACE inhibitor pathway	CTSG	NR3C2	ATP6AP2	KNG1	CMA1	NOS3	REN	BDKRB1	AGT	ACE2	ACE	AGTR1	AGTR2	MAS1	BDKRB2	TGFB1	CYP11B1;CYP11B2	
15Q11Q13 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5407%HOMO SAPIENS	15q11q13 copy number variation	TJP3	TJP2	CREBBP	SPEF1	SMC5	SMC6	NSMCE3	NSMCE2	CDC42BPB	NSMCE1	EID3	GJD3	NECAB3	LYPD6	GJC2	GJA1	UBN1	GCOM1;MYZAP	TRPM3	RELA	RIC3	APP	SLF1	CANX	SLF2	FAM189A1	CGN	DNMBP	MITF	APBA2	FANCD2	ANKRD2	CALM1	FANCI	STXBP1	TJP1	CXADR	MTMR10	KLF13	OTUD7A	CHRNA7;CHRFAM7A	TRPM1	KAT2B	CCL5	SERPINH1	FAN1	STX1A	SIN3A	HDAC1	OCLN-1	
TELOMERE END PACKAGING AND NEURODEVELOPMENTAL DISORDERS%WIKIPATHWAYS_20260910%WP5567%HOMO SAPIENS	Telomere end packaging and neurodevelopmental disorders	POT1	TPP1	H4C6	TERF1-1	TERF2	H2AZ2;H2AZ1	H2AJ	H2BC8;H2BC6;H2BC4;H2BC10;H2BC7	TERF2IP	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	H2BC5	H2BC1	H2BC15;H2BC3;H2BC11;H2BC12	H2AC20	H2AB2;H2AB3;H2AB1	H4-16	H2BC21	ACD	TINF2	H2AC14	H4C1	
6Q16 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5400%HOMO SAPIENS	6q16 copy number variation	INSR	MC4R	SIM1	NPY	GHSR	GHRL	LEP	POMC	AGRP	NTRK2	BDNF	LEPR	INS;INS-IGF2	ARNT	
MULTIPLE SCLEROSIS MECHANISM AND THERAPIES%WIKIPATHWAYS_20260910%WP5540%HOMO SAPIENS	Multiple sclerosis mechanism and therapies	MS4A1	S1PR1	S1PR4	S1PR3	S1PR5	ITGB1	BTK	ITGA4	
SMALL LIGAND GPCRS%WIKIPATHWAYS_20260910%WP247%HOMO SAPIENS	Small ligand GPCRs	PTGFR	PTGER3	LPAR1	S1PR4	TBXA2R	PTGDR	PTGIR	CNR2	PTGER4	PTGER2	S1PR1	S1PR3	S1PR2	PTAFR	CNR1	MTNR1A	MTNR1B	PTGER1	GPR50	
DEGRADATION PATHWAY OF SPHINGOLIPIDS INCLUDING DISEASES%WIKIPATHWAYS_20260910%WP4153%HOMO SAPIENS	Degradation pathway of sphingolipids including diseases	HEXB	NEU2	GM2A	PSAP	NEU1	HEXA	GLB1	LIPA	NPC2	ARSA	GBA	GALC	NEU3	SCARB2	NEU4	NPC1-1	GLA	
NOD LIKE RECEPTOR NLR SIGNALING%WIKIPATHWAYS_20260910%WP288%HOMO SAPIENS	Nod like receptor NLR signaling	CHUK	IKBKG	MAP3K7	RELA	MAPK8	ERBIN	EPHB2	CD40	IKBKB	
EMBRYONIC STEM CELL PLURIPOTENCY PATHWAYS%WIKIPATHWAYS_20260910%WP3931%HOMO SAPIENS	Embryonic stem cell pluripotency pathways	WNT11	MAPK7	MAPK6	MAPK4	WNT7B	MAPK12	ELK1	FGF21	CTNNB1	FOS	EGF	PDGFB	PDGFRB	FGF2	MDM2-2	HNF1A	LIF	BMP4	MAP2K6	MAP2K3	JUN	RAF1	FZD1	FZD3	WNT3A	WNT5A	WNT7A	ACVR1	WNT3	LRP6	AKT2	AKT3	AKT1	MTOR	GSK3B	PIK3R2	MAP2K2;MAP2K1	MAPK1	JAK1	STAT3	GAB1	PTPN11	GRB2	ACVR2B	IL6ST	SOS1	DVL1	PDGFA	DVL2	FGF20	DVL3	FGF23	FGF22	FGF17	FGF16	ACTR2	PDGFRA	FGF19	SMAD7	PTEN	FGF1	AXIN1	FGF3	FGF4	FGF5	FGF6	EGFR	FGF7	FGF8	FGF9	FGF14	WNT5B	APC	FGF13	FGF12	FGF11	HRAS	WNT6	WNT1	WNT2	WNT4	WNT10B	SMAD1	WNT10A	SMAD4	FZD2	FZD5	FZD4	FZD7	FZD6	FZD9	SMAD9	FZD8	ARAF	SMAD5	FGF18	FGFR4	BMPR1B	FGFR3	FGFR2	BMPR1A	FGF10	FGFR1	WNT2B	SELENOP	BMPR2	PIK3CD	NOG	LIFR	MAP2K5	SMAD6	WNT9B	BRAF	WNT16	ERAS	LRP5	
DISORDERS OF FOLATE METABOLISM AND TRANSPORT%WIKIPATHWAYS_20260910%WP4259%HOMO SAPIENS	Disorders of folate metabolism and transport	ST20-MTHFS;MTHFS	ALDH1L1	MTHFR	QDPR	SHMT1	SLC46A1	ALDH1L2	MTHFD2L	TYMS	MTR-1	FTCD	ATIC	SLC19A1	DHFR2;DHFR	FOLR1	MTHFD1	MTHFD2	GART	SHMT2	
IRON SULFUR CLUSTER BIOGENESIS%WIKIPATHWAYS_20260910%WP5152%HOMO SAPIENS	Iron sulfur cluster biogenesis	ISCU	NARF	ABCB7	NUBP1	NUBP2	NFS1	LYRM4	FDX1	FDXR	FXN	CIAO2B	GLRX5	HSPA9	HSCB	NFU1	
APOE AND MIR 146 IN INFLAMMATION AND ATHEROSCLEROSIS%WIKIPATHWAYS_20260910%WP3926%HOMO SAPIENS	ApoE and miR 146 in inflammation and atherosclerosis	TRAF6	IRAK1	RELA	TLR2	SPI1	TLR4	APOE	NFKB2	
TYPE I COLLAGEN SYNTHESIS IN THE CONTEXT OF OSTEOGENESIS IMPERFECTA%WIKIPATHWAYS_20260910%WP4786%HOMO SAPIENS	Type I collagen synthesis in the context of osteogenesis imperfecta	PLOD1	ADAMTS2	COL1A1	SP7	COL1A2	WNT1	P4HB	LOX	BMP1	P4HA1	TNFSF11	P4HA2	CREB3L1	TNFRSF11B	FZD1	TNFRSF11A	SERPINH1	LRP6	MBTPS1	FKBP10	MIA3	PLOD2	TMEM38B	COLGALT1	SERPINF1	IFITM5	CRTAP	P3H2	P3H1	MBTPS2	ITPR1	PPIB	LRP5	
REGULATION OF SISTER CHROMATID SEPARATION AT THE METAPHASE ANAPHASE TRANSITION%WIKIPATHWAYS_20260910%WP4240%HOMO SAPIENS	Regulation of sister chromatid separation at the metaphase anaphase transition	SMC1A	RAD21	STAG1	PTTG1;PTTG2	SMC3	CENPE	CDC20	ESPL1	BUB1B	BUB3	MAD2L1	BUB1	MAD1L1	APC	
TGF BETA RECEPTOR SIGNALING IN SKELETAL DYSPLASIAS%WIKIPATHWAYS_20260910%WP4816%HOMO SAPIENS	TGF beta receptor signaling in skeletal dysplasias	MAPK9	MAPK3	JAK1	SERPINE1	CREBBP	STAT1	ITGB6	STAT3	EP300	CTNNB1	FOS	FBN1	EGF	SPP1	IFNG	SKIL	SMAD7	TNF	LEF1	LIF	ADAMTSL2	LTBP3	ADAMTS10	BMP4	RUNX2	HRAS	WNT1	SMAD1	SMAD4	JUN	TGFBR1-1	TFE3	SMAD2;SMAD3	SMAD9	SMAD5	RUNX3	ZFYVE9	TGIF1-1	FST	LEFTY2;LEFTY1	NOG	FOXH1	TGFBR3	ZEB2	ENG	LTBP1	THBS1	ZNF423	INHBA	SMAD6	FKBP1A	SKI	BAMBI	TGFB1	NFKB1	TGFBR2	
LET 7 INHIBITION OF ES CELL REPROGRAMMING%WIKIPATHWAYS_20260910%WP3299%HOMO SAPIENS	let 7 inhibition of ES cell reprogramming	POU5F1;POU5F1B	MYC	KLF4	SOX2	EGR1	TRIM71	
TCA CYCLE IN SENESCENCE%WIKIPATHWAYS_20260910%WP5050%HOMO SAPIENS	TCA cycle in senescence	GOT1-1	PDHA1	MDH1	BRAF	PDK1	PDP2	FH	ME1	ME2	TP53	
SLC25A46 PATHWAY%WIKIPATHWAYS_20260910%WP5521%HOMO SAPIENS	SLC25A46 pathway	APOOL	MMGT1	IMMT	MICOS10	APOO	CHCHD3	CHCHD6	EMC1	SLC25A46	EMC2	EMC3	EMC4	EMC6	EMC7	EMC8	EMC10	DNM1L	MFN1	MFN2	MICOS13	OPA1	
IL1 SIGNALING%WIKIPATHWAYS_20260910%WP195%HOMO SAPIENS	IL1 signaling	TRAF6	MAP3K7	MAPK9	MAPK3	NFKBIB	MAP2K4	MAP3K2	MAPK14	ATF2	IKBKB	PTPN11	IKBKG	CHUK	RELA	NFKBIA	IL1A	IL1RAP	IRAK1	IRAK2	MAP3K3	TOLLIP	SQSTM1	TAB3	TAB2	TAB1	MAP3K14	MYD88	IL1B	MAPKAPK2	MAPK8	PLCG1	PRKCZ	IRAK3	PELI1	MAP2K7	PELI2	UBE2N	MAP2K6	MAP2K3	JUN	MAP3K1	UBE2V1	IL1R1	ECSIT	AKT1	REL	PIK3R2	PIK3R1	IRAK4	MAP2K2;MAP2K1	NFKB1	MAPK1	HSPB2	
EBOLA VIRUS INFECTION IN HOST%WIKIPATHWAYS_20260910%WP4217%HOMO SAPIENS	Ebola virus infection in host	ITGB3	IRF3	VPS11	VPS16	ITGAV	ITGA4	EP300	ITGA3	FOLR1	TFAP2A	ITGA2	ITGA1	VAV2	ACTG1	ITGA6	RELA	ITGA5	FLNA	VPS33A	ACTN1	ACTN4	CDC42	PAK1	RFC1	CLTC	CLTA	HLA-DPB1-1	ACTB-1	HLA-DRB5;HLA-DRB1;HLA-DRB3;HLA-DRB4	HLA-DOA	VPS41	HLA-DOB	HLA-DRA	HLA-DPA1	EIF2AK2	HLA-DQB2;HLA-DQB1	RELB	HLA-DMB	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	CLEC4M;CD209-2	RAB9A	FLNB	FLNC	HAVCR2	CLTCL1	MBL2-1	BST2	NPC2	AKT1	MFGE8	ADAM17	REL	PIK3R2	PIK3R1	NPC1-1	SOCS3	NFKB1	NFKB2	MAPK1	RAC1	TOP1	MAPK3	RHOB	CREBBP	STAT1	EIF2S1	RAB5A	TPCN2	NEDD4	IGF1R	RHOC	TYRO3	RASA2	C1QBP	GAS6	IL4	EPS15	MERTK	PRKRA	TLR4	RAB7A	IQGAP1	EGFR	IRF7	CTSB	PIK3R3	ICAM2	GSN	ICAM3	KPNA1	TIMD4	RHOA	CLEC4G	SCIN	VPS39	CLEC6A	CLTB	ASGR1	DAB2IP	HLA-DMA	CTSV;CTSL	AXL	TIAM1	PIK3CD	TSG101	PIK3CB	CAV3	CAV2	CAV1	TBK1	PIK3CA	VPS4A	ITGB1	IKBKE	VPS18	DDX58	
ADIPOGENESIS%WIKIPATHWAYS_20260910%WP236%HOMO SAPIENS	Adipogenesis	UCP1	RXRA	FOXC2	PPARGC1A	PPARD	CTNNB1	RB1	CDKN1A	CEBPA	CNTFR	STAT5A	STAT5B	KLF6	LIPE	CFD	E2F4-1	NRIP1	ID3	CELF1	CREB1	TNF	NCOA2	GDF10	HNF1A	NCOR1	PPARA	RBL1	E2F1	LIF	GADD45B	GADD45A	IGF1	BMP4	BMP2	NR1H3	LMNA	ZMPSTE24	FAS	WWTR1	FRZB	SREBF1	IRS1	IRS2	ADIPOQ	NR3C1	FOXO1-1	LPIN1	INS;INS-IGF2	LPIN2	NR2F1	DDIT3	RXRG	FZD1	EBF1	MEF2D	STAT2	SCD	CISD1	IRS4	RBL2	SOCS1	RARA	NAMPT	STAT6	PRLR	TGFB1	SOCS3	EPAS1	TRIB3	MEF2A	MEF2B;BORCS8-MEF2B	ASIP	NCOA1	SERPINE1	NCOR2	STAT1	MIF	STAT3	LEP	GATA4	AGT	CYP26A1	IL6	IL6ST	SFRP4	NDN	CEBPB	OSM	CYP26B1	DVL1	AGPAT2	BSCL2	LPIN3	SP1	EGR2	CEBPD	GATA3	GATA2	KLF15	KLF5	AHR	MEF2C	WNT5B	HIF1A	PTGIS	MIXL1	WNT1	BMP3	WNT10B	BMP1	MBNL1	GTF3A	PLIN2	SPOCK1	RORA	KLF7	PCK1	SMAD2;SMAD3	SLC2A4	PCK2	PNPLA3	LIFR	RETN	PPARG	LPL	PLIN1	DLK1	
HAIR FOLLICLE DEVELOPMENT CYTODIFFERENTIATION STAGE 3 OF 3%WIKIPATHWAYS_20260910%WP2840%HOMO SAPIENS	Hair follicle development cytodifferentiation stage 3 of 3	FOXQ1	GPRC5D	DKK1	CCN2	GTPBP4	CTNNB1	GJB6	FOS	ZBTB16	TP63	MSX1	KITLG	IFNG	DSC2	DKK4	EGR2	GLI2	GATA3	RBPJ	SOX9	GAS1	LEF1	EGFR	SFRP1	CD34	S100A4	IGF1	BMP4	TCF4	NOTCH2	KLK6	NOTCH1	WIF1	IGFBP5	KRTAP8-1	BMP6	DKK3	SOX2	SMAD1	SMAD4	NR3C1	ELANE	JUN	MSX2	FOXE1	HR	CD200	HOXC12	PHLDA1	SPINK6	LHX2	SPINK5	KRTAP3-2;KRTAP3-3-1	ADAMTS20	DSG1	FZD1	DSG4	DLX3	PROM1	NFATC1	CASP14	RUNX3	KLK5	WNT5A	KLK4	KLK7	BMPR1A	CUX1	LRIG1	FST	GSDMA	KLK13	SOSTDC1	KLK14	BCL11B	FOXN1	KRT19	KRTAP2-2;KRTAP2-1;KRTAP2-3;KRTAP2-4-2	LGR5	ADAM17	FOSB	NFKB1	PERP	KRT15	
KETOGENIC DIET IN EPILEPTOGENESIS%WIKIPATHWAYS_20260910%WP5639%HOMO SAPIENS	Ketogenic diet in epileptogenesis	SLC2A1	HDAC3	HDAC2	LDHA	GAD1	ERBB4	HMGCS1-1	GLUD1;GLUD2	HCAR2;HCAR3	TXNIP	SLC25A14	SLC25A27	UCP2	AKT3	SIRT4	NFE2L2	HDAC8	KCNA1	ABCC8	PPID	HDAC1	NLRP3	RPS6	CAT	NRG1	PPARG	KCNJ11	
TYPE III INTERFERON SIGNALING%WIKIPATHWAYS_20260910%WP2113%HOMO SAPIENS	Type III interferon signaling	IRF9	JAK1	STAT2	STAT1	IFNLR1	IFNL2;IFNL3;IFNL1	IL10RB	TYK2	
IRON METABOLISM IN PLACENTA%WIKIPATHWAYS_20260910%WP2007%HOMO SAPIENS	Iron metabolism in placenta	TFRC	ACO1	TF	TFR2	SLC11A2	HEPHL1	SLC40A1	MCOLN1	STEAP3	HAMP	IREB2	
SEROTONIN AND ANXIETY%WIKIPATHWAYS_20260910%WP3947%HOMO SAPIENS	Serotonin and anxiety	GABRA1	HTR2A	CAMK2B	PPP3CA	FMR1	GRM1	HTR1A	PLCD4	POMC	FOS	ARC	ADRA1A	EEF2K	PLEK	PRKCB	TRPV1	CRH	
NUCLEOTIDE EXCISION REPAIR IN XERODERMA PIGMENTOSUM %WIKIPATHWAYS_20260910%WP5114%HOMO SAPIENS	Nucleotide excision repair in xeroderma pigmentosum	H4C6	CUL4A	GPS1	ERCC3	ERCC4	POLE2	RPA3	ERCC1	POLE3	ERCC2	ERCC8	ERCC6	CUL4B	UVSSA	BRCA1	RFC1	DDB2	XAB2	POLK	CCNH	LIG1	LIG3	RBX1	RPA2	XPA	XPC	H3-3A	USP7	XRCC1	PARP1	SLX4	CDK7	MNAT1	CETN2	POLE	POLH	RFC5	RFC3	RFC4	RFC2	RAD23A	RAD23B	DDB1	GTF2H2C;GTF2H2C_2;GTF2H2	POLD3	POLD4	POLD1	POLD2	PCNA	SLX4IP	H4-16	HMGN1	RPA1	GTF2H1	CHD1L	GTF2H3	RAD18	GTF2H4	H4C1	POLE4	
OMEGA 3 OMEGA 6 FATTY ACID SYNTHESIS%WIKIPATHWAYS_20260910%WP4723%HOMO SAPIENS	Omega 3 omega 6 fatty acid synthesis	PLA2G5	PLA2G6	FADS2	ACSL1	JMJD7-PLA2G4B;PLA2G4B	FADS1	ACOX1	PLA2G4A	ACOX3	ELOVL2	ELOVL5	ACOT2;ACOT1	ACSL3	ACSL4	
HYPOTHETICAL CRANIOFACIAL DEVELOPMENT PATHWAY%WIKIPATHWAYS_20260910%WP3655%HOMO SAPIENS	Hypothetical craniofacial development pathway	TFAP2A	RHOA	ARHGEF2	TP63	IRF6	ARHGAP29	TGFB3	
NON GENOMIC ACTIONS OF 1 25 DIHYDROXYVITAMIN D3%WIKIPATHWAYS_20260910%WP4341%HOMO SAPIENS	Non genomic actions of 1 25 dihydroxyvitamin D3	CYP27B1	MAPK9	MAPK3	JAK1	MAPK7	RXRA	PLCG2	STAT1	PRKCD	MAPK14	MAPK12	MAPK13	IKBKB	ISG15	TYK2	MAPK11	DEFB4A;DEFB4B	PLCD1	IL6	CXCL8	IFNG	CD40LG	SP1	TLR8	TLR4	TNF	RELB	PRKCG	PRKCH	PRKCB	PRKCE	PRKCA	PRKCQ	CAMK2B	CAMK2D	NRAS	MAPK8	CAMK2A	HRAS	PRKCZ	PLCB3	VDR	PLCB4	SP3	MED1	CAMK2G	TNFRSF1A	PLCB1	PLCB2	KRAS	JUN	ETS1	NOD2	CYP24A1	CD40	RXRB	RXRG	IFNGR1	IFNAR2	STAT2	IFNGR2	TLR2	CAMP	CCL13;CCL2	IFI44L	CAV1	IFI27L2	PLCE1	RSAD2	NFKB1	MAPK1	NFKB2	
DISORDERS IN KETONE BODY SYNTHESIS%WIKIPATHWAYS_20260910%WP5175%HOMO SAPIENS	Disorders in ketone body synthesis	HMGCL	HMGCS2	BDH1	OXCT1-1	ACAT1	
MITOCHONDRIAL COMPLEX II ASSEMBLY%WIKIPATHWAYS_20260910%WP4920%HOMO SAPIENS	Mitochondrial complex II assembly	SDHC	SDHD	SDHA	SDHAF2	SDHAF3	SDHB	SDHAF1	SDHAF4	
SOMATROPH AXIS GH AND ITS RELATIONSHIP TO DIETARY RESTRICTION AND AGING%WIKIPATHWAYS_20260910%WP4186%HOMO SAPIENS	Somatroph axis GH and its relationship to dietary restriction and aging	SIRT1	MTOR	IGF1R	FOXO1-1	PTEN	AKT1	
VITAMIN D METABOLISM%WIKIPATHWAYS_20260910%WP1531%HOMO SAPIENS	Vitamin D metabolism	CYP2R1	CYP27B1	CYP27A1	RXRA	PTH	CYP24A1	RXRB	VDR	DHCR7	GC	
CYTOSINE METHYLATION%WIKIPATHWAYS_20260910%WP3585%HOMO SAPIENS	Cytosine methylation	IDH2	DNMT1	IDH1	MECP2	TET2	TET1	MBD3	TDG	
CAFFEINE IN NEURONS%WIKIPATHWAYS_20260910%WP5602%HOMO SAPIENS	Caffeine in neurons	ADRA1B	ADRA1A	ADORA2A	ADRA1D	
ENDOCHONDRAL OSSIFICATION WITH SKELETAL DYSPLASIAS%WIKIPATHWAYS_20260910%WP4808%HOMO SAPIENS	Endochondral ossification with skeletal dysplasias	NKX3-2	MGP	ADAMTS1	CHST11	ALPL	PLAT	STAT1	PLAU	DDR2	CDKN1C	IGF1R	CAB39	ACAN	MMP9	STAT5B	SPP1	KIF3A	BMP7	FGF2	IHH	HDAC4	IFT88	SOX9	SOX6	SOX5	VEGFA	MEF2C	IGF1	CALM1	RUNX2	COL10A1	IGF2	GHR	FRZB	PTH1R	HMGCS1-1	BMP6	SCIN	THRA	CTSV;CTSL	PTCH1	SLC38A2	FGF18	ADAMTS5	PRKACA-1	MMP13	RUNX3	FGFR3	BMPR1A	SERPINH1	FGFR1	TIMP3	COL2A1	AKT1	GLI3	ENPP1	PTH	TGFB2	TGFB1	ADAMTS4	PTHLH	
PTF1A RELATED REGULATORY PATHWAY%WIKIPATHWAYS_20260910%WP4147%HOMO SAPIENS	PTF1A related regulatory pathway	CTNNB1	RBPJ	NKX6-1	PTF1A	RBPJL	KAT2B	NOTCH1	HES1	PROX1	FGF10	PDX1	
IL17 SIGNALING%WIKIPATHWAYS_20260910%WP2112%HOMO SAPIENS	IL17 signaling	JAK2	TRAF6	MAP3K7	IL17RE	MAPK3	NFKBIB	JAK1	IL17RC	STAT3	IKBKB	IKBKG	TRAF3IP2	RELA	TRAF3	CEBPB	IL25	SP1	IL17RB	CEBPD	AKT1	IL17RA	GSK3B	IL17RD	IL17D	PIK3CA	IL17C	IL17F	IL17B	NFKB1	MAPK1	IL17A	MAP3K14	
MIR TARGETED GENES IN LYMPHOCYTES%WIKIPATHWAYS_20260910%WP2004%HOMO SAPIENS	miR targeted genes in lymphocytes	NRP1	BCKDHB	RHEB	CACNA2D1	CCND1	VCAM1	GNAI2	FGF2	AP2A1	UBE2J1	MAP3K8	SLC38A1	HARS1	CPNE8	VEZT	ACAA2	SRPRB-1	ZEB1	ARF4-1	PWP1	DHX57	ARFIP1	CIAO2A	POGLUT3	RARS1	TPM3	FNDC3B	G6PD	FNDC3A	GOLGA7-1	DHX40	IDH1	RAB34	RAI14	ABCF2-H2BE1;ABCF2	SRSF9	TMED10	CBFB	MRPL20	COMMD9	SLC38A2	ANPEP	ATP6V1C1	ATP6V1F	PEDS1-UBE2V1;PEDS1	SLC4A10	TBCA	MOV10	NCL-1	HNRNPM	WNT5A	CHMP2A	ANP32B	PICALM	TRAM1	ADAR	MAGT1	MRC2	SPTLC1	SH3BGRL3	TMED7	TMED2-1	ELOVL5	ATRX	SIGMAR1	CAPG	PRPF40A	CSDE1	TCL1A	POM121;POM121C	PXDN	PTMA	PNP-1	MTPN	SEC23A	MRPS33	AKAP8	DNAJB1	POLR2C	PPP1R7	SH3BP4	PDLIM7	MPZL1	SLC12A2	GALNT7	TXNRD1	GALNT1	AP3D1	ARCN1	TMEM59	SPCS3	FMNL2	ATP6V0E2;ATP6V0E1	GYS1	NEDD4	PDCD4	LAMTOR5	PLXND1	BET1	FXR2	COL4A2	NCOA3	EGFR	E2F3	PRKCI	SLC12A4	ARL10	NOTCH2	NOTCH1	TYMS	LAMC2	LAMC1	DNMT3B	TRIP13	MTHFD2	SMAD1	CXCL12	PANX1	RAB5C	BCL6	CPOX	PPP2R5C	CDKN2A	MAT2A	MAPK7	MAPK14	MAPK12	CTNNB1	RB1	PKN2	CDKN1A	CSNK1D	CDKN1B	CLOCK	SMC1A	SLC25A22	SLC25A13	SUCLG2	ARHGDIA	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	E2F1	IQGAP3	CDK6	IRS1	MYLIP	FBXW11	DDX5	RAD23B	TDG	GFPT1	POLD2	USP1	TGFBR2	POLE4	IFRD1	CCN1	GPD2	CAP1	PHC2	HIPK3	CUL4B	IGF2R	CSRP1	ELMOD2	CDKN1C	CEBPB	SERPINE2	C1orf56	DCAF7	TERT	PRIM1	KCNN4	SAC3D1	HMOX1	ADPGK	ATAT1	PTRH1	SYPL1	UNC93B1	HDAC4	POLA2	MYB	NELFCD	MYCN	KRAS	NF2	CLDN1	GPAM	MET	AXL	STRN	FADS2	FADS1	NT5C3A	MYO1E	PPP5C	NFIA	IPO4	CHAF1A	LMNB2	LPL	RRP8	HOXA5	GTPBP3	OTULINL	PKM	CEP72	VTI1B	FERMT2	HOXD8	VAMP3	TAF9B	TRMT1	LY6K	MSI2	NPR3-1	ARFIP2	BRI3BP	RCOR1	MEOX2	PURA	MTX1	YIF1B	GEMIN2	ARID2	UTP15	MARS2	RBM19	PTBP1	DHX15	PPP3R1	PTBP2	KIT	NT5E	PPP3CA	TUBA1A	BACE1	SRSF10	CDIPT	EIF4E	TNFSF9	BCL2	CYP1B1	SEC24A	PPIF	RTN4	RHOB	GSTM4	ATP2A2	AGO3;AGO1	SYNE2	SYNE1	TMEM43	GNA13	TPM1	CDKAL1	CYP51A1	BACH1	RAB23	CHORDC1	RAVER2	CDK5RAP1	ANKFY1	SEC62	TRPV6	VPS39	CDK5RAP3	TMEM41B-1	MBNL1	SCAMP1	CARHSP1	METTL7A-1	PDE3A	WDR82	KCNQ1	FAR1	HACD3	GRPEL2	ATP6V0A1	SNX6	RAB27B	NCEH1	SFXN1	PTPA	GFM1	ASH2L	PTPRJ	PTPRF	COIL	PISD	TMED3	GNL3L-1	GNPNAT1	CTSC	MRPS24	RHOG	AP3B1	GAK	SLC7A6	CDCP1	FRG1	BRPF3-1	SSNA1	AMIGO2	NAPG	PGRMC1	SHOC2	SPRYD4	TTC9C	WDR11	TPPP3	SNX15	LRRC8A	NUCB1	LAMTOR3	TUSC2	LTN1	ARID4B	SDCBP	LCLAT1	ABHD10	KPNA3	TPM4	TPM2	ATG9A	GAS2L1	STX7	ITGA2	UBE4A	RAB30	DMTF1	WDFY1	MATR3	GEMIN7	SLC1A4	UAP1	CORO1C	SLC9A3R2	RAB6A	ANAPC1	CD164	CNOT9	SLC25A1	DOCK5	CALCOCO2	SNAP23	DOCK7	TNFAIP2	CHD1	TMEM109	PLK1	ACP2	SNAP29	SCYL1	HSDL1	ARID1A	RCN2	RFT1	RBMS1	LUZP1	YWHAQ	NUFIP2	NXN	UHRF1	CAND1	TP53INP1	IGF2BP1	ZNF622	PDLIM5	SLC25A24	MYO10	EHMT2	TM6SF1	SLC4A7	EHMT1	SLC25A32	NAA15	DNMT3A	EZH2	UBE2S	ANXA2	PLAG1	BDNF	ADIPOR2	RDH10	NARS1	PPIB	ABCG2	MTRR	TXN2	C1QBP	ATG3	ATAD3A;ATAD3B	MCL1	HSD17B12	PGM1	P4HA2	PSAT1	THEM4	AURKB	PAFAH1B2	ABHD11	MPDU1	
CORI CYCLE%WIKIPATHWAYS_20260910%WP1946%HOMO SAPIENS	Cori cycle	SLC2A1	SLC2A4	GPT	ALDOA	LDHA	GAPDH-1	PGAM1	PGK1	SLC2A2	HK1	TALDO1	G6PD	PFKP	INS;INS-IGF2	TPI1	GPI	
7 OXO C AND 7 BETA HC PATHWAYS%WIKIPATHWAYS_20260910%WP5064%HOMO SAPIENS	7 oxo C and 7 beta HC pathways	CYP7A1	EBP	EPHX2	DHCR7	ACOX2	ACOT2;ACOT1	SLC27A5	HSD11B1	HSD11B2	SCP2	NPC2	THEM5	ACOT9	ACOT8	ACOT7	ACOT11	ACOT12	ACOT13	CYP27A1	DBP	AMACR	BAAT	ACOT6	NPC1-1	SLC27A2	ACOT4	
RAS SIGNALING%WIKIPATHWAYS_20260910%WP4223%HOMO SAPIENS	Ras signaling	RASGRF2	MAPK9	PLA2G5	PLA2G6	JMJD7-PLA2G4B;PLA2G4B	RAC3	HTR7	ETS2	ELK1	IKBKB	MAPK10	CHUK	GAB2	RELA	CALML6	CALML3	CALML4	FOXO4	RIN1	PRKACB-1	RASAL1	RASAL2	CDC42	RASAL3	PAK1	TTBK1	BRAP	RGL1	PAK3	RGL2	PAK2	RASA4;RASA4B	PAK4	KDR	PLAAT3	RASSF5	KSR2	RALGDS	PLA2G2F	RASGRP2	LAT	PLA2G2E	PDGFRB	PLA2G2C	RASGRP4	PLD2	RASGRP3	GNB5	GRIN2A	ABL1	RALB	KIT	GRIN2B	CALM1	CALM2	RASGRF1	RASA1	PLA2G2A-1	MAPK8	PLA2G4A	RAF1	CALM3;CALM1	GRIN1	FLT3	AKT2	AKT3	AKT1	REL	PLCE1	PIK3R2	PIK3R1	ZAP70	STK4	NFKB1	MAP2K2;MAP2K1	EPHA2	MAPK1	AFDN	RAC1	GNG10	ARF6	MAPK3	NGFR	GNG13	PLCG2	NTRK1	BAD	ABL2	GAB1	PTPN11	RAB5A	GNGT1	IKBKG	IGF1R	RRAS	GRB2	PLD1	SOS1	BCL2L1	RASA2	SHC4	SHC1-1	SHC2	INSR	PDGFRA	FLT4	PLA2G2D	PLA2G12A	PLA2G4F	PLA2G12B	PLA2G4D	PLA2G4E	PLA2G3	CSF1R	SOS2	PLA2G10;LOC100652777	EGFR	RAPGEF5	PRKCG	PRKCB	GNB2	PRKCA	GNB1	GNB4	GNB3	RASGRP1	NRAS	PLCG1	PLA2G1B	PIK3R3	PLA1A	HRAS	SYNGAP1	NF1	RALBP1-1	RHOA	RALA-1	RASA3	EXOC2	KRAS	ETS1	BUB1B-PAK6;PAK6	MET	GNG2	GNG5	PAK5	FGFR4	GNG4	PRKACA-1	GNG8	FGFR3	TIAM1	FGFR2	RAB5B	RAB5C	FGFR1	PIK3CD	RRAS2	MRAS	SHC3	PIK3CB	RAP1B	RAP1A	FASLG	TEK	KSR1	NTRK2	PIK3CA	FLT1	RASSF1	SHOC2	
GENE REGULATORY NETWORK MODELING SOMITOGENESIS %WIKIPATHWAYS_20260910%WP2854%HOMO SAPIENS	Gene regulatory network modeling somitogenesis	DLL1	EPHA4	MESP2	WNT3A	FGF8	NOTCH1	HES1	LFNG	TBX6	HES7	RIPPLY2	
CONTROL OF IMMUNE TOLERANCE BY VASOACTIVE INTESTINAL PEPTIDE%WIKIPATHWAYS_20260910%WP4484%HOMO SAPIENS	Control of immune tolerance by vasoactive intestinal peptide	IL2	IL4	IFNG	FAS	IL12A	IL5	CD86	CD80	CTLA4	VIP	TGFB1	CD28	IL10	
B CELL RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP23%HOMO SAPIENS	B cell receptor signaling	MAP3K7	MAPK9	TEC	CD79B	CD19	CD79A	PLCG2	CD81	PIP5K1A	MAPK4	PIP5K1B	PRKCD	PIP5K1C	MAPK14	ATF2	ELK1	GAB1	IKBKB	PDPK1	PTPN11	IKBKG	CHUK	VAV1	GAB2	VAV2	CR2	RAPGEF1	CBL	PTPRC	RELA	GRB2	INPP5D	SOS1	CRK	LYN	SYK	BTK	NFKBIA	SHC1-1	CARD11	BCL10	PTPN6	MALT1	MAX	CDC42	MYC	CREB1	BLK	KLF11	DAPP1	RASGRP3	SH3BP2	PTPN18	GSK3A	NFATC3	PRKCB	MAPK8	CAMK2A	PLCG1	HRAS	NFATC2	MAP4K1	RPS6KA1	MAP2K6	FOXO1-1	JUN	ETS1	NCK1	CRKL	BLNK	PIK3AP1	RAF1	CD22	LCK	GTF2I	FYN	AKT1	HCLS1	PIK3CG	BCL6	REL	GSK3B	PIK3R2	BRAF	PIK3R1	LAT2	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	
2Q37 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5224%HOMO SAPIENS	2q37 copy number variation syndrome	ITGB3	ILK	SEPTIN2	NFKBIA	MYO5A	CALCRL	CAPN10	ASCL1	TNF	TP53	DGKD	HDLBP	HJURP	ERFE	KLHL30	PASK	THAP4	AGAP1	COPS9-1	ESPNL	TRPM8	OR6B2	UBE2F	MTERF4	CXCL11	CALM1	STK25	SNED1	RTP5	GMEB1	RNPEPL1	ING5	IL1B	LRRFIP1	KIF1A	ILKAP	PER2	AQP12B	DUSP28	OTOS	ARL4C	SCLY	ATG4B	USP40	ARF5	DTYMK	ASB18	CENPA	CYTH2	CYTH4	SPP2	PRLH	CYTH1	FARP2	SEPTIN6	MAB21L4	JUN	MLPH	RAB17	RBM44	ASB1	DISC1	NDUFA10	IL13RA1	GBX2	MAP1LC3A	PRL	RPS6	ARF1	MYOG	RAC1	MEF2A	PPP1R7	SH3BP4	PDCD1	CYTH3	AGXT	GYS1	D2HGDH	RRAGC	RAMP1	RRAGA	CALCA	RRAGB	RRAGD	ABCA1	PDGFA	BOK	SEPTIN4-1	GPC1	CFLAR	TRAF3IP1	HDAC4	UGT1A1;UGT1A6	NEU4	EGFR	MAP1LC3B2;MAP1LC3B-1	HES1	GABARAPL2	HES6	MEF2C	SEPTIN12	GABARAP	EEF1A1	MAP1LC3C	CXCR4	CXCL12	HAMP	ACKR3-2	TRAF3	COL6A3	GPR35	RAB27A	COPS8	IQCA1	TWIST2	IRF8	MYOD1	ITPK1	PDX1	
HYPOTHESIZED PATHWAYS IN PATHOGENESIS OF CARDIOVASCULAR DISEASE%WIKIPATHWAYS_20260910%WP3668%HOMO SAPIENS	Hypothesized pathways in pathogenesis of cardiovascular disease	SMAD2;SMAD3	RUNX2	MAPK3	SERPINE1	MAPK8	MAPK14	NR2C2	CCN2	TGFBR3	ANGPT2	ENG	LTBP1	AGTR1	POSTN	SMAD4	FBN1	FLNA	TGFBR1-1	SHC1-1	FBN2	FBN3	MAPK1	LTBP2	TGFBR2	
TGFB SMAD SIGNALING%WIKIPATHWAYS_20260910%WP5382%HOMO SAPIENS	TGFB Smad signaling	SMAD2;SMAD3	POSTN	YWHAG	SMAD4	SERPINE1	TGFBR1-1	WWTR1	SPARC	CCN2	TGFBR3	TGFBR2	
EV RELEASE FROM CARDIAC CELLS AND THEIR FUNCTIONAL EFFECTS%WIKIPATHWAYS_20260910%WP3297%HOMO SAPIENS	EV release from cardiac cells and their functional effects	MYB	KLF2	PRL	RGS16	CXCL12	ERBB4	
PARTHANATOS CELL DEATH SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP5585%HOMO SAPIENS	Parthanatos cell death signaling pathway	MIF	AIFM1	PARP1	
ENDOCHONDRAL OSSIFICATION%WIKIPATHWAYS_20260910%WP474%HOMO SAPIENS	Endochondral ossification	NKX3-2	MGP	ADAMTS1	CHST11	ALPL	PLAT	STAT1	PLAU	DDR2	CDKN1C	IGF1R	CAB39	ACAN	MMP9	STAT5B	SPP1	KIF3A	BMP7	FGF2	IHH	HDAC4	IFT88	SOX9	SOX6	SOX5	VEGFA	MEF2C	IGF1	CALM1	RUNX2	COL10A1	IGF2	GHR	FRZB	PTH1R	HMGCS1-1	BMP6	SCIN	THRA	CTSV;CTSL	PTCH1	SLC38A2	FGF18	ADAMTS5	PRKACA-1	MMP13	RUNX3	FGFR3	BMPR1A	SERPINH1	FGFR1	TIMP3	COL2A1	AKT1	GLI3	ENPP1	PTH	TGFB2	TGFB1	ADAMTS4	PTHLH	
OXIDATION BY CYTOCHROME P450%WIKIPATHWAYS_20260910%WP43%HOMO SAPIENS	Oxidation by cytochrome P450	CYP2J2-1	CYP4F22	CYP19A1	CYP27B1	CYP2C18-1	CYP4X1	CYP7A1	CYP2B6	CYP17A1	CYP2A13;CYP2A6;CYP2A7-1	CYP11A1	CYP2F1	CYP51A1	CYP4B1	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	CYP4F3;CYP4F2;CYP4F12;CYP4F11	CYP26A1	CYP27C1	CYP2S1	CYP8B1	CYP1A1	CYP2W1	CYP24A1	CYP11B1;CYP11B2	CYP26B1	CYP20A1	CYB5R2	CYP4V2	CYB5R1	CYP2R1	CYB5A	CYB5R4	CYP46A1	POR	CYP2D6;LOC107987479;LOC107987478-1	CYP2C9;CYP2C19	CYP1B1	CYP39A1	CYP7B1	CYP27A1	CYP2U1	CYP2E1	CYB5R3	
15Q25 COPY NUMBER VARIATION%WIKIPATHWAYS_20260910%WP5408%HOMO SAPIENS	15q25 copy number variation	SH3GL3	RNMT	SLC2A1	DNM3	TOP1	BNC1	RYR2	GRM5	AP3D1	GRM1	SPCS3	SPCS1	NMBR	RYR1	SHANK1	PDE8A	EGF	RAF1	RAMAC	ZNF592	ADAMTSL3;ADAMTSL1	TENT4B	AP3M2	BTBD1	C15orf40	FSD2	SHANK3	WHAMM	SEC11A	NMB	AP3B2	HTT	AP3S2;AP3S1	SPCS2	WDR73	ALPK3	HOMER2	SLC28A1	ZSCAN2	ITPR1	TM6SF1	CPEB1	AGAP2	SYNJ1	
MICRORNA FOR TARGETING CANCER GROWTH AND VASCULARIZATION IN GLIOBLASTOMA%WIKIPATHWAYS_20260910%WP3593%HOMO SAPIENS	MicroRNA for targeting cancer growth and vascularization in glioblastoma	HEY1	VEGFC	HES1	VEGFA	HIF1A	VEGFB	HIF1AN	
DYRK1A INVOLVEMENT REGARDING CELL PROLIFERATION IN BRAIN DEVELOPMENT%WIKIPATHWAYS_20260910%WP5180%HOMO SAPIENS	DYRK1A involvement regarding cell proliferation in brain development	DLL1	PSEN1	REST	LATS2	CDKN1B	SMARCB1	APP	GLI1	CASP9	TFDP1	TFDP2	CASP3	E2F4-1	CCND1	DCAF7	CREB1	FGF2	TP53	APH1A	NCSTN	GMNN	RBL1	HES1	HES5	E2F5	CSNK1A1	DNM1	H3-3A	DEPTOR	CDK6	CDK4	NOTCH1	PSENEN	BACE1	SPRY2	HIP1	SIRT1	MAPT	FOXO1-1	EIF2B5	DYRK1A	RPTOR	NFATC1	TSC2	DNER	MLST8	NEUROG2	RBL2	AMPH	MTOR	TSC1	LIN54	LIN52	GSK3B	RAD54L2	LIN37	LIN9	TFAP4	AKT1S1	RBBP4	CRY2	
CARDIAC HYPERTROPHIC RESPONSE%WIKIPATHWAYS_20260910%WP2795%HOMO SAPIENS	Cardiac hypertrophic response	MAP3K7	MEF2A	MAPK3	MAPK7	PRKG1	MAP2K4	MAPK14	IKBKB	PDPK1	IKBKG	CHUK	EGF	FGF2	TNF	HDAC4	HDAC5	HDAC9	HDAC7	NRG1	IGF1	CDK9	CALM1	MAP3K14	PRKCA	PPP3CA	PRKD1	PLA2G2A-1	CAMK2D	MAPK8	CDK7	NPPA	NFATC2	MAP4K1	TNFRSF1A	MAP2K7	MAP2K6	MAP2K3	MAP3K1	TGFBR1-1	RAF1	FGFR2	AKT2	AKT1	MTOR	MAP2K5	GSK3B	LOC118142757;GUCA1A	TGFB1	IKBKE	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	
STEROID HORMONE PRECURSOR BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP5277%HOMO SAPIENS	Steroid hormone precursor biosynthesis	SRD5A2	AKR1D1	CYP17A1	HSD3B1;HSD3B2	CYP11A1	CYP21A2	SRD5A1	
IL18 SIGNALING%WIKIPATHWAYS_20260910%WP4754%HOMO SAPIENS	IL18 signaling	TRAF6	MAP3K7	MEF2A	MAPK9	MAPK3	PRKAA1	PRKCD	IKBKB	CTNNB1	CHUK	RPS6KB1	IRF1	RELA	IL18R1	NFKBIA	CASP3	CEBPB	IL18	TICAM2	SP1	NCF1	CFLAR	PTEN	TNF	TP53	CYCS-1	IL37	IRAK1	BID	GRIN2B	NFATC4	PRKCB	NOX1	PRKCA	MYD88	CASP8	FAS	BAX	ELAVL1	PARP1	TNFRSF1A	MAP2K7	NCF2	ACACB	IL18RAP	LCK	HSPB1	FASLG	GSK3B	PIK3R1	GATA1	IMP3	CSN2-1	SLC12A3	NFKB1	MAPK1	
PYRIMIDINE METABOLISM%WIKIPATHWAYS_20260910%WP4022%HOMO SAPIENS	Pyrimidine metabolism	TK1	POLR3B	ENTPD3	POLR1A	NME3	POLR2C	POLR3D	CTPS2	POLR1B	CTPS1	POLE2	POLR3E	DCTD	POLR1D	NT5M	NME6	CMPK1	POLR1E	CMPK2	POLE3	UPRT	POLR3H	DCTPP1	NME4-1	POLR3K	RRM1	DUT	UCKL1	DHODH	NME2	UCK1	POLA1	RRM2-1	PRIM2	PRIM1	RRM2B	POLA2	ENPP3	NME7	POLR2A	TYMS	ENTPD1	DTYMK	NME1	POLR1C	DCK	POLE	POLR2D	POLR2L	DPYS	CAD	UPB1	POLR1F	TYMP	NT5C	POLR1H	POLR3GL	TK2	POLD3	POLR3A	UMPS	POLD4	POLR3C	POLR3F	DPYD	POLR3G	POLD1	POLD2	ENPP1	POLR2B	POLR2E	POLR2G	POLR2H	POLR2I	PNPT1	CDA	UPP1	POLE4	POLR2J;POLR2J2;POLR2J3	
PI3K AKT MTOR VITAMIN D3 SIGNALING%WIKIPATHWAYS_20260910%WP4141%HOMO SAPIENS	PI3K AKT mTOR vitamin D3 signaling	MYC	PDHA1	LDHA	TSC2	RXRA	IL12A	VDR	HK3	CD86	AKT1	MTOR	PFKFB4	CD80	TSC1	HLA-DRA	GSK3B	RELA	PRKAA2	PIK3CA	CYP24A1	IL10	
IL2 SIGNALING%WIKIPATHWAYS_20260910%WP49%HOMO SAPIENS	IL2 signaling	RPS6KB2	IL2RA	IL2RB	MAPK3	JAK1	STAT1	HRAS	STAT3	PTPN11	NMI	JAK3	GAB2	MAPT	RPS6KB1	CBL	GRB2	SOS1	STAT5A	STAT5B	SYK	CRKL	SHC1-1	RAF1	LCK	IL2	FYN	FOXO3	AKT1	IL2RG	PTK2B	CISH	RPS6	PIK3R1	SOCS3	MAP2K2;MAP2K1	MAPK1	
TESSADORI BICKNELL VAN HAAFTEN SYNDROME VARIANTS NUCLEOSOME ASSEMBLY%WIKIPATHWAYS_20260910%WP5573%HOMO SAPIENS	Tessadori Bicknell van Haaften syndrome variants nucleosome assembly	H4C6	DAXX	ATRX	H4-16	CHAF1B	H2BC15;H2BC3;H2BC11;H2BC12	CHAF1A	RBBP4	HIRA	SMIM40	H4C1	
PLEURAL MESOTHELIOMA%WIKIPATHWAYS_20260910%WP5087%HOMO SAPIENS	Pleural mesothelioma	PPARGC1A	FGF21	ACTG1	RHEB	PRKAA2	PRKAG1	PRKAG2	EGF	FN1	PRKAG3	AREG	FOSL1	CCND1	MYC	PRKAB2	PRKAB1	STK38L	TNIK	SELE	PDGFB	RPS6KA5	FGF2	ACTB-1	GABPA	IL34	MKNK1	MKNK2	MAP3K3	CXCL2;CXCL3;CXCL1-1	IGF1	IL1B	MAPK8	MMP3	FZD1	MMP14	LGALS9C;LGALS9;LGALS9B	FZD3	MEF2D	WNT3A	WNT5A	WNT7A	WNT3	LRP6	AKT2	AKT3	AKT1	MTOR	MAP3K6	GSK3B	MAP2K2;MAP2K1	EPHA2	MAPK1	MINK1	ADAMTS1	PDGFD	MAPK3	DKK1	PDGFC	JAK1	NGFR	MAP2K4	MAP3K2	STAT1	SOST	SLC7A5	IL6	IGF1R	RPS6KB1	FRAT2	GRB2	CSNK2A2	SOS1	SFRP4	CSNK2B	VEGFB	SHC1-1	IL10	VEGFD	TCF7	DVL1	DVL2	KITLG	FGF20	DVL3	FGF23	FGF22	FGF17	TNNT1	HMGB1-1	SP1	PDGFRA	FGF19	FLT4	COL4A2	PTEN	COL4A1	COL4A4	FZD10	COL4A6	FGF1	CSF1R	AXIN1	CSNK2A1;CSNK2A3	FGF3	FGF4	SLC3A2	FGF5	EFNA4	LEF1	EGFR	FGF6	FGF7	FGF8	FGF9	EFNA1	BAK1	EFNA3	EFNA2	FGF14	TCF7L2	TCF7L1	CSNK1A1	WNT5B	APC	RPS6KB2	FGF13	FGF12	ACTC1;ACTG2	FGF11	KMT2C	LIMD1	LAMC3	STK3	SAV1	LAMC2	YAP1-1	LAMC1	TEAD1	MAP4K3	TEAD3	MAP4K4	WNT6	TEAD4	WNT1	MAP4K1	WNT2	MAP4K2	WNT4	NGF	MST1	WNT10B	LATS1	ACTA1	WNT10A	SETD5	FZD2	CXCL12	LAMA5	FZD5	LAMA2	LAMA1	FZD7	LAMA4	LAMA3	FZD6	FZD9	AJUBA	FZD8	FGF18	FGFR4	EIF4B	SETDB1	FGFR3	ANGPT4	FGFR2	EED	LAMB3	FGF10	FGFR1	LAMB2	PDK1	WNT2B	LAMB1	PIK3CD	PIK3CB	PIK3CG	TEK	CDKN2A	NTRK2	WNT16	PIK3CA	FLT1	FOXM1	RASSF1	LRP5	PGF	MAPK9	WNT11	MAPK7	WDR5	WNT7B	MAPK14	BTRC	ASXL1	BAP1	MAPK10	MOB1A;MOB1B	CTNNB1	LATS2	CDKN1A	BRCA1	BBC3	NTF4	FLT3LG	OGT-1	CCND3	CCND2	RNF2	MAX	CD47	RASSF5	CREB1	CCNE1	TP53	MDM2-2	CYCS-1	SOX17	CER1	SERPINF1	E2F1	SFRP2	SFRP5	CTBP2	PORCN	KREMEN1	SENP2	CXXC4	CDK4	CDK2	WIF1	NOTUM	BAX	ATM	CDK7	FOXO1-1	INS;INS-IGF2	FLT3	CCL5	CD274	CCL13;CCL2	TGFB1	NFKB1	CXCL10	CSF3	CSF2	NTRK1	PLAU	CCN2	HGF	MMP2	MMP9	PDGFA	TGFA	CCL4L2;CCL4L1;CCL4	TERT	CSF1	CASP1	NLRP3	VEGFA	MAD2L1	IGF2	HIF1A	LIN28B	HRAS	NF2	MET	PAK5	COL4A3	COL4A5	NTF3	CHD8	RING1	HMGN1	RBBP4	CXCL5;CXCL6	PRKAA1	ATF2	ELK1	ATG13	DKK2	KDR	DKK4	ULK2	ULK1	PDGFRB	ACTA2	BARD1	SFRP1	KIT	WWC1	CTBP1	RYK-1	ROR1	ROR2	PLCB4	RPS6KA3	RPS6KA1	MAP3K9	MAP2K7	MAP3K4	MAP2K6	MAP2K3	JUN	MAP3K1	DDIT3	BCL2	MAP3K10	RAF1	MAP3K11	YY1	FABP4	MAP3K5	CDH9	AMOT	CDH7	ITPR3	CDH5	CDH4	CDH3	AGER	CDH20	CDH22	BTC	CDH24	CDH10	HBEGF	CDH11	CDH12	CDH13	CDH15	CDH17	CDH18	VGLL4	PHC1	TPTEP2-CSNK1E;CSNK1E	CDH19	PRSS23	MCU	DSC3	BAG2	MDK	RASSF2	RASSF3	RB1CC1	RASSF4	TRAF2	RASSF6	BECN1	HCFC1	EFNA5	CTHRC1	BUB1B-PAK6;PAK6	MAP2K5	CDH8	PTK2	ITGB1	ITGB4	ITGB3	ITGB2	ITGAV	PODXL	ITGA4	KIF23	ITGA3	ITGA2	ITGA1	ITGA6	MAD1L1	SRC	PAK1	CUL1	PAK3	PAK2	PAK4	YWHAB	UHRF1	IDO1	MAPKAPK2	EZH2	WWTR1	MDM4	BDNF	RASSF7	TEAD2	CDH1	CTNNA1	CTNNA3	CTNNA2	TSC2	RPS6	SETD2	EIF4EBP1	ATF3	KDM6A	CDH6	CIT	CDH2	CDH16	INSR	SPARC	MCL1	SLC2A1	DEPTOR	BMI1	TELO2	CD44	EIF4G1	TTI1	SUZ12	PIGF	RPTOR	MLST8	ANGPT2	ANGPT1	TSC1	VEGFC	NDRG1	AKT1S1	
4 HYDROXYTAMOXIFEN DEXAMETHASONE AND RETINOIC ACIDS REGULATION OF P27 EXPRESSION%WIKIPATHWAYS_20260910%WP3879%HOMO SAPIENS	4 hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression	RAF1	EIF4EBP1	MAP3K11	PBK	MAPK3	PRKAA1	TSC2	PIK3R3	PIK3CD	PIK3CB	AKT1	MTOR	MAP3K5	TSC1	EIF4E	MKNK1	MKNK2	MAP2K6	MAP2K3	PIK3R2	PIK3R1	PIK3CA	MAP2K2;MAP2K1	MAPK1	
TRANSCRIPTION FACTOR REGULATION IN ADIPOGENESIS%WIKIPATHWAYS_20260910%WP3599%HOMO SAPIENS	Transcription factor regulation in adipogenesis	SLC2A4	INSR	NRIP1	MAPK8	RXRA	CREB1	PPARGC1A	CEBPD	TNF	LEP	PCK2	IL6	CEBPA	IRS1	ADIPOQ	IRS2	FOXO1-1	NR3C1	LPIN1	PPARG	CEBPB	
AUTOPHAGY IN PANCREATIC DUCTAL ADENOCARCINOMA%WIKIPATHWAYS_20260910%WP5331%HOMO SAPIENS	Autophagy in pancreatic ductal adenocarcinoma	AGER	PINK1	HMGB1-1	STAT3	PRKN	TP53	NFE2L2	MDM2-2	KRAS	MAP1LC3B2;MAP1LC3B-1	IPO8	TFEB	VMP1	SQSTM1	BECN1	MITF	NFKB1	SHOC2	ATG7	TFE3	
TRYPTOPHAN METABOLISM%WIKIPATHWAYS_20260910%WP465%HOMO SAPIENS	Tryptophan metabolism	IL4I1	IDO1	HADH	TPH1	ECHS1	STAT1	ACAT1	GCDH	ALDH2	CYP1A1	DLD	AOC1	TPH2	ALDH8A1	AOX1	AANAT	AHR	DDC	MAOA	GOT2-1	AADAT	HAAO	ASMT	ACMSD	INMT	KMO	CAT	TDO2	KYNU	AFMID	KYAT3	KYAT1	IDO2	
FANCONI ANEMIA%WIKIPATHWAYS_20260910%WP5465%HOMO SAPIENS	Fanconi anemia	BRIP1	RAD50	MCM2	FANCI	RAD51	ERCC4	MEN1	FANCM	FANCL	UBE2T	FANCA	ERCC1	FANCC	FANCE	PALB2	FANCG	SLX4	FANCF	ATM	ATR	MRE11	BRCA1	RFWD3-2	DCLRE1B	UHRF2	CTDP1	NBN	RAD51C	FAAP24	PTEN	FANCD2	FAN1	CEBPD	BRCA2	SMARCA4	LOC105377022;FANCB	XRCC2	USP1	FAAP100	UHRF1	REV1	EGFR	HSP90B1	CENPX	CENPS-CORT;CORT;CENPS	MAD2L2	
NF KB SIGNALING AND ARTD FAMILY MEMBERS%WIKIPATHWAYS_20260910%WP5527%HOMO SAPIENS	NF kB signaling and ARTD family members	CREBBP	MAVS	BTRC	PARP1	IKBKB	EP300	PARP14	IKBKG	CHUK	SKP1	NFKBIA	ZC3HAV1	TIPARP	TFPI2	PARP16	CUL1	PARP12	CLDN6	PARP10	ERN1	GSK3B	EIF2AK3	RBX1	RELB	TBK1	NFKB2	DDX58	MAP3K14	
EGF EGFR SIGNALING%WIKIPATHWAYS_20260910%WP437%HOMO SAPIENS	EGF EGFR signaling	MAPK9	MAPK7	MAPK4	MAPK14	VAV3	ELK1	PDPK1	GAB2	VAV2	FOS	GJA1	DOK2	CBL	INPP5D	CRK	STAT5A	STAT5B	JUND	EGF	FOXO4	ROCK1	RIN1	SRC	CDC42	PAK1	CSK	ERBB2	RALGDS	CREB1	RPS6KA5	BCAR1	PLD2	AP2A1	AP2M1	ABL1	RALB	E2F1	ATXN2	RICTOR	MAP3K3	DNM1	RASA1	AP2B1	ELK4	STXBP1	MAPK8	SH3GL2	SPRY2	AP2S1	RPS6KA3	RPS6KA2	RPS6KA1	MAP3K4	FOXO1-1	JUN	MAP3K1	RAF1	NDUFA13	MEF2D	TNK2	PTK6	INPPL1	AKT1	CBLC	MTOR	PIAS3	PLCE1	PIK3R2	FOSB	PIK3R1	PXDN	MAP2K2;MAP2K1	SYNJ1	MAPK1	RAC1	JAK2	EIF4EBP1	CBLB	MEF2A	NCK2	ARF6	JAK1	MAP3K2	STAT1	PRKCD	STAT3	GAB1	PTPN11	RAB5A	VAV1	NEDD4	RPS6KB1	LIMK2	GRB2	PLD1	SOS1	GRB10	SHC1-1	ERRFI1	PLSCR1	USP8	USP6NL	PEBP1	CFL1	EPS8	STAMBP	STAM2	SP1	IQSEC1	SH3KBP1	EPS15	EPS15L1	PTEN	ASAP1	REPS2	PTPN12	ITCH	NCOA3	ARHGEF1	SOS2	PTK2B	IQGAP1	EGFR	MEF2C	PRKCI	EPN1	PRKCB	SH3GL3	PRKCA	ABI1	PLCG1	CAMK2A	PRKCZ	HRAS	STAM	MAP4K1	RALBP1-1	RALA-1	KRAS	NCK1	CRKL	PTPN5	STMN1	ATF1	NOS3	HGS	RAP1A	MAP2K5	PIK3C2B	PCNA	CAV2	PTPRR	CAV1	BRAF	PTK2	
HEPATITIS B INFECTION%WIKIPATHWAYS_20260910%WP4666%HOMO SAPIENS	Hepatitis B infection	IRF3	MAPK9	DDX3X-1	MAVS	MAPK14	ATF2	MAPK12	ELK1	MAPK13	IKBKB	MAPK10	EP300	MAPK11	JAK3	CHUK	CDKN1A	FOS	RELA	CASP9	STAT5A	STAT5B	EGR3	CASP3	SRC	MYC	APAF1	DDB2	VDAC3	CREB1	TNF	ATF4	IFNB1-4	YWHAB	YWHAQ	CYCS-1	IRAK1	BID	TAB2	TAB1	MYD88	MAPK8	CASP8	FAS	BAX	FADD	TICAM1	MAP2K7	MAP2K6	MAP2K3	JUN	MAP3K1	TGFBR1-1	BCL2	CREB3L2	RAF1	ATP6AP1	DDB1	STAT2	AKT2	AKT3	AKT1	IFNAR1	STAT6	PIK3R2	TGFB2	PIK3R1	TGFB1	YWHAZ	TGFB3	IRAK4	NFKB1	MAP2K2;MAP2K1	MAPK1	TGFBR2	JAK2	TRAF6	MAP3K7	MAPK3	JAK1	MAP2K4	CREBBP	STAT1	BAD	STAT3	TYK2	IKBKG	SLC10A1	IL6	CREB3L3	GRB2	CREB3L4	CREB3L1	MMP9	SOS1	CXCL8	ATF6B	TICAM2	TIRAP	EGR2	TLR4	TLR3	HSPG2	SOS2	PTK2B	PRKCG	IRF7	NFATC3	NFATC4	PRKCB	PRKCA	NRAS	PIK3R3	HRAS	NFATC2	KRAS	SMAD4	CREB5	TRAF3	STAT4	SMAD2;SMAD3	ARAF	NFATC1	BIRC5	TLR2	PIK3CD	PIK3CB	FASLG	PCNA	IFIH1	CREB3	TBK1	BRAF	CASP10	PIK3CA	IKBKE	DDX58	
CHEMOKINE SIGNALING%WIKIPATHWAYS_20260910%WP3929%HOMO SAPIENS	Chemokine signaling	CCR9	ADCY8	WAS	VAV3	IKBKB	JAK3	CHUK	VAV2	CCL27	CCL26	RELA	CRK	STAT5B	XCL1;XCL2	NFKBIA	ROCK1	ROCK2	PRKACB-1	CDC42	PAK1	CCR8	CSK	CCR6	PF4;PF4V1-1	CX3CR1	GRK2	GNAI3	RASGRP2	GNAI2	CCL1	CXCR6	BCAR1	CXCL13	CCL20	GNB5	CCL25	CCL24	CXCR5	ADCY1	CCL19	CXCL2;CXCL3;CXCL1-1	TIAM2	PARD3	CCL21	CXCL11	WASL	PLCB3	PLCB4	CCL17	PLCB1	CCL22	PLCB2	CX3CL1	CCL23;CCL15	RAF1	STAT2	GRK1	CCL5	AKT2	AKT3	AKT1	FGR	GRK6	GSK3B	PIK3R2	PIK3R1	NFKB1	MAP2K2;MAP2K1	MAPK1	RAC1	CXCL10	JAK2	GNG10	NFKBIB	MAPK3	GNG13	GRK5	STAT1	GRK4	PRKCD	STAT3	GNGT1	CCR3	CCR2	IKBKG	VAV1	ITK	ARRB1	ARRB2	HCK	GRB2	CCL28	LYN	SOS1	CCL3L1;CCL3L3;CCL3;CCL18	ADCY4	SHC4	ADCY2	SHC1-1	SHC2	CCL11	ADCY7	ADCY6	CCL4L2;CCL4L1;CCL4	ADCY5	NCF1	ADCY9	CXCL14	PREX1	ELMO1	CXCL9	DOCK2	SOS2	PRKX	PTK2B	PPBP	PRKCB	GNB2	GNB1	GNB4	GNB3	ADCY3	GNAI1	NRAS	PIK3R3	CCR10	PRKCZ	HRAS	PIK3R5	CCR1	XCR1	KRAS	CXCR4	CXCL12	CRKL	GNG2	GNG5	CCR7	GNG4	GNG8	TIAM1	CCR4	FOXO3	PIK3CD	SHC3	PIK3CB	PXN	RAP1B	PIK3CG	RAP1A	BRAF	CXCR3	PTK2	PIK3CA	CXCR2	CXCL5;CXCL6	
CELL TYPE DEPENDENT SELECTIVITY OF CCK2R SIGNALING%WIKIPATHWAYS_20260910%WP3679%HOMO SAPIENS	Cell type dependent selectivity of CCK2R signaling	CCK	RYR3	RYR2	GNAI1	CCKBR	DAGLA	GNAQ	PLCB1	RYR1	CD38	CNR1	TRPC1	ITPR1	
DOCOSAHEXAENOIC ACID OXYLIPIN METABOLISM%WIKIPATHWAYS_20260910%WP5154%HOMO SAPIENS	Docosahexaenoic acid oxylipin metabolism	PTGS2-2	EPHX2	
BUTYRATE INDUCED HISTONE ACETYLATION%WIKIPATHWAYS_20260910%WP2366%HOMO SAPIENS	Butyrate induced histone acetylation	ACLY	AKT1	
GPR40 ROLE IN INSULIN SECRETION%WIKIPATHWAYS_20260910%WP3958%HOMO SAPIENS	GPR40 role in insulin secretion	FFAR1	GNA11	PLCG2	PLCG1	PKD1	PLCB3	PLCH1	PLCD3	PLCD1	PLCB1	PLCL1	PLCB2	PLCZ1	PLCE1	ITPR3	
TRANSLATION INHIBITORS IN CHRONICALLY ACTIVATED PDGFRA CELLS%WIKIPATHWAYS_20260910%WP4566%HOMO SAPIENS	Translation inhibitors in chronically activated PDGFRA cells	PRKCA	RPS6KB2	EIF4EBP1	MAPK9	MAPK3	MAP2K4	MAPK8	PIK3R3	PRKCD	MAPK14	MAPK10	EIF4G1	RPS6KA2	RPS6KA1	PDCD4	EIF4A2	MAP2K7	EIF4E	RPS6KB1	MAP2K6	MAP2K3	RPTOR	EIF4G3	PRKACA-1	EIF4B	RPS6KA5	PDK1	AKT2	AKT3	PIK3CB	AKT1	MTOR	PIK3CG	RPS6KA4	CSNK2A1;CSNK2A3	MAP2K5	PIM2	PIK3R2	RPS6	PIK3R1	PIK3CA	PIM1	MAP2K2;MAP2K1	MAPK1	EIF4A1	
LIPOPROTEIN METABOLISM IN PERIPHERAL TISSUES%WIKIPATHWAYS_20260910%WP5620%HOMO SAPIENS	lipoprotein metabolism in peripheral tissues	APOC3	LIPC	APOC2	APOA1	PLTP	CETP	APOE	APOB	LPL	LCAT	
FATTY ACID BETA OXIDATION%WIKIPATHWAYS_20260910%WP143%HOMO SAPIENS	Fatty acid beta oxidation	ACADM	HADH	ACADS	LIPC	ACSL6	ACSL5	ECHS1	GPD2	ACAT1	GCDH	CPT1A	CHKB	GK	PNPLA2	HADHB-1	DLD	ACSS2	ACSL3	CPT1B	TPI1	CPT2	LIPE	ACSL1	CRAT	DECR1	ACADVL	ECI1	ACSL4	GK2	LIPF	HADHA	LPL	ACADL	SLC25A20	
RIBOFLAVIN AND COQ DISORDERS%WIKIPATHWAYS_20260910%WP5037%HOMO SAPIENS	Riboflavin and CoQ disorders	FLAD1	RFK	PDSS2	COQ6	COQ2	ETFDH	APTX	ETFA	COQ9	COQ7	SLC52A1;SLC52A2	PDSS1	COQ8A	
TYPE II INTERFERON SIGNALING%WIKIPATHWAYS_20260910%WP619%HOMO SAPIENS	Type II interferon signaling	JAK2	CXCL10	IL1B	JAK1	REG1B;REG1A	STAT1	PRKCD	SPI1	ICAM1	PTPN11	ISG15	IRF2	IRF1	NOS2	IFNGR1	STAT2	IFNGR2	IFNG	TAP1	CIITA	IFNB1-4	OAS1	IRF9	CXCL9	CYBB	IRF4	SOCS1	IRF8	PSMB9	EIF2AK2	IFIT2	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	SOCS3	GBP2;GBP3;GBP1	
NETRIN UNC5B SIGNALING%WIKIPATHWAYS_20260910%WP4747%HOMO SAPIENS	Netrin UNC5B signaling	CDH5	MAPK3	NTN4	ROBO4	NTN3	ALPL	COL1A1	MAPK14	ICAM1	CCN2	PTPN11	INPP5D	CASP3	IL10	SRC	VCAM1	IL1A	SELE	KDR	TNF	TP53	ARHGEF12	PTK2B	DAPK1-1	RGMA	NTN1	UNC5B	CIP2A	PRKCA	RLF	PLEKHH1	NEO1	PPP1CA	YAP1-1	RHOA	DCSTAMP	JUN	RAF1	PTPA	FYN	AKT1	CCL13;CCL2	MYF5	PIK3CA	PTK2	PPP2R1B	MAP2K2;MAP2K1	AGAP2	MAPK1	ITGB4	RAC1	
PI3K AKT MTOR SIGNALING AND THERAPEUTIC OPPORTUNITIES IN PROSTATE CANCER%WIKIPATHWAYS_20260910%WP3844%HOMO SAPIENS	PI3K AKT mTOR signaling and therapeutic opportunities in prostate cancer	EIF4EBP1	NRAS	BAD	PIK3R3	HRAS	CDKN1B	RHEB	RB1CC1	KRAS	FOXO1-1	GRB10	FOXO4	RPTOR	ATG13	TSC2	MAPKAP1	NOS3	MLST8	PDK1	ULK1	PTEN	FOXO3	PIK3CB	AKT1	MTOR	PIK3CG	GSK3B	PIK3R2	RICTOR	PIK3R1	PIK3CA	TFEB	
MITOCHONDRIAL FISSION AND FUSION%WIKIPATHWAYS_20260910%WP4318%HOMO SAPIENS	Mitochondrial fission and fusion	MTFP1	BAX	SH3GL2	BNIP3	PHB	DNM1L	MIB1	MFN1	MFN2	PLD1	BCL2L1	FIS1	OPA1	
16P11 2 DISTAL DELETION SYNDROME%WIKIPATHWAYS_20260910%WP4950%HOMO SAPIENS	16p11 2 distal deletion syndrome	JAK2	C3-1	RABGEF1	CD19	NFATC2IP	TUFM	ATXN2L	SPNS1	CD81	RAB5A	NFATC2	VAV2	ATP2A1	CR2	TRAF1	GRB2	TRAF2	IFITM3;IFITM2;IFITM1	INSR	IL4	KDR	SH2B1	LAT	CD82	PRMT1	RABEP2	MPL	RAB4A	
APOPTOSIS%WIKIPATHWAYS_20260910%WP254%HOMO SAPIENS	Apoptosis	IRF3	NFKBIB	PRF1	MAP2K4	BAD	CASP5;CASP4	IKBKB	MAPK10	IKBKG	CHUK	IRF2	IGF1R	TP63	IRF1	BBC3	RELA	CASP9	TRAF2	BCL2L1	NFKBIA	CASP3	MYC	HRK	APAF1	BOK	BIRC2	BIRC3	TNFRSF25	DIABLO-1	CFLAR	TNF	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	TP53	BCL2L2	MDM2-2	CYCS-1	CASP7	CASP1	PMAIP1	CASP6	CASP2	IRF7	BAK1	BID	MCL1	IGF1	SCAF11	IGF2	CASP8	FAS	BAX	TRADD	XIAP	RIPK1	FADD	CRADD	TNFRSF1A	HELLS	LTA	TRAF1	TNFRSF21	JUN	GZMH;GZMB-1	MAP3K1	TRAF3	BCL2	DFFB	DFFA	NFKBIE	TNFRSF1B	BIRC5	IRF6	BCL2L11	BNIP3L	AKT1	TP73	FASLG	IRF4	IRF5	CDKN2A	CASP10	PIK3R1	TNFSF10	NFKB1	
IL1 AND MEGAKARYOCYTES IN OBESITY%WIKIPATHWAYS_20260910%WP2865%HOMO SAPIENS	IL1 and megakaryocytes in obesity	IL18	MYD88	SELENBP1	IL1B	IL1R1	TLR1	IFNG	TIMP1	HBEGF	TLR2	F2R	TIMP2	ICAM1	CCR3	CCL13;CCL2	PLA2G7	FCER1A	IRAK1	F2	NLRP3	MMP9	PIK3CA	S100A9	NFKB1	
MAMMARY GLAND DEVELOPMENT PREGNANCY AND LACTATION STAGE 3 OF 4%WIKIPATHWAYS_20260910%WP2817%HOMO SAPIENS	Mammary gland development pregnancy and lactation stage 3 of 4	JAK2	PTPN1	NFIB	PNCK	ERBB3	DLGAP4	ERBB4	TTC9	GJB2	GAL	HDGFL2	EIF4G1	CHUK	TPM3	CEBPA	EIF4E	TNFSF11	USF1	NR3C1	STAT5A	STAT5B	BCL2L1	CEBPB	ORAI1	ESR1	ELF5	TFPI2	CCND1	MYC	YY1	CLDN6	NFIX	TNFRSF11A	ERBB2	ESR2	PGR	PRL	EGFR	NFIA	CAV1	NFIC	PRLR	ATP2C2	NRG1	USF2	CSN2-1	
ROBO4 AND VEGF SIGNALING CROSSTALK%WIKIPATHWAYS_20260910%WP3943%HOMO SAPIENS	ROBO4 and VEGF signaling crosstalk	SLIT2	ROBO4	KDR	VEGFA	SRC	RAC1	
ESTRADIOL REGULATION IN PORTO SINUSOIDAL VASCULAR DISEASE%WIKIPATHWAYS_20260910%WP5235%HOMO SAPIENS	Estradiol regulation in porto sinusoidal vascular disease	SP1	CALM1	ESR1	SP3	KCNN3	
INTEGRATED BREAST CANCER PATHWAY%WIKIPATHWAYS_20260910%WP1984%HOMO SAPIENS	Integrated breast cancer pathway	EP300	CTNNB1	RB1	CHUK	CSNK1D	MRE11	RHEB	BRCA1	DAG1	CASP9	CDC25B	CHEK2	CASP3	ESR1	CHEK1	MAX	FOSL1	CDC42	CCND1	PAK1	MYC	DHTKD1	RHO	CDC25A	TFPI	PLK1	CREB1	FAU	RASGRP3	TP53	MDM2-2	BLM	ABL1	BARD1	E2F1	NOXA1	MSH6	BID	GSK3A	MSH2	ERAL1	UBE2F	GADD45A	EDAR	MYT1	TAB1	JAKMIP1	PML	RAD50	RAD51	CDK4	CDK2	CASP8	BAX	ATM	TRADD	CDK7	ATR	FADD	CERK	IRS1	GRN	FOXO1-1	JUN	TGFBR1-1	BCL2	CDH1	TSC2	SELENOK	RAD54L	PIAS1	SMARCA4	HIPK2	AKT1	MTOR	FOSL2	HDAC1	PIK3R2	AURKA	NFKB1	MAP3K13	MAPK1	RAC1	TGFBR2	ZMIZ1	CYP19A1	JAK1	AR	STAT1	BAD	PKIA	MMP1	ANXA1	RRAS	NUP85	TPR	STK11	SP1	SMAD7	PTEN	BRCA2	WEE1	PHB	XRCC3	NCOA3	AHR	EGFR	VEGFA	PPP4R3A	BAK1	PPP4R3B	GDI1	MYCBP2	BACH1	NF1	NAB1	SIRT1	MAP3K7CL	ZMYND8-1	RALA-1	ALKBH1	RALGAPA1	CCNB1IP1	SMAD1	PLK3	KRAS	SMAD4	FER	PIGR	USP38	IMPA1	ZNF655	RASGEF1A	DCAKD	ITPKC	USP15	USP16	SMAD2;SMAD3	USP21	FILIP1	ARAF	ATF1	BMPR1A	BMPR2	HMGCR	TSC1	RAP1A	RPP38	SMAD6	BRAF	ODC1	
FGF23 SIGNALING IN HYPOPHOSPHATEMIC RICKETS AND RELATED DISORDERS%WIKIPATHWAYS_20260910%WP4790%HOMO SAPIENS	FGF23 signaling in hypophosphatemic rickets and related disorders	CCND1	GALNT3	DMP1	PHEX	CYP27B1	FGF23	SLC34A1	SPP1	FAM20C	FGFR3	ALPL	FGFR2	KL	CDKN1A	ENPP1	PTH	ROS1	CYP24A1	NFKB1	CYP11B1;CYP11B2	ORAI1	NFKB2	
MITOPHAGY%WIKIPATHWAYS_20260910%WP5636%HOMO SAPIENS	Mitophagy	MAPK9	NLRX1	TOMM40	TOMM70	EIF2S1	MAPK10	ATG9A	RAB5A	ARIH1	SMURF1	MTX1	TRAF2	TOMM20	CSNK2A2	BCL2L1	OPA1	MITF	BECN1	SRC	BECN2	AMBRA1	CALCOCO2	USP8	RHOT1	SP1	ULK1	RAB7A	ATF4	PRKN	BNIP3	PHB2	CSNK2A1;CSNK2A3	E2F1	EIF2AK3	MFN1	MFN2	MARCHF5-1	NBR1	ATG9B	FKBP8	SQSTM1	RABGEF1	BCL2L13	MAPK8	PINK1	HIF1A	VCP-1	KRAS	JUN	USP15	TFE3	PGAM5	CITED2	FUNDC1	USP30	OPTN-1	MUL1	TAX1BP1	RAB5B	RAB7B	RAB5C	SAMM50	FOXO3	TBC1D17	CCZ1;CCZ1B	SIAH1	BNIP3L	TBC1D15	HUWE1	TOMM7	MAP1LC3A	AMFR	TBK1	TFEB	FIS1	
BARDET BIEDL SYNDROME%WIKIPATHWAYS_20260910%WP5234%HOMO SAPIENS	Bardet Biedl syndrome	BBS4	ZIC2	BBS9	CRX	LCA5	BBS7	CEP290	CLUAP1	BBS5	RP2	TMEM216	CEP104	ARL3	ARL13B	TMEM67	INPP5E	PDE6D	NPHP3	NEK8	NEK1	BBS2	BBS1	IFT172	MKS1	IFT74	TTC8	CFAP410	MAK	EVC2	CEP41	TRAF3IP1	TTC21B	GLI2	KIF7	PKHD1	EVC	DCDC2	C8orf37	GPR161	WDPCP	ARL6	ARNTL	BBIP1	INVS	USP9X	EFHC1	SMO	PKD2	TMEM107	MKKS	PKD1L1	BBS10	BBS12	CILK1	PCARE	RAB23	SCLT1	CNGA1	TRIM32	DYNC2H1	DYNC2I2	LZTFL1	DYNC2I1	CNGB1	PTCH1	IFT140	DYNLT2B	WDR19	IFT122	IFT80	WDR35	FUZ	DYNC2LI1	IFT43	IFT81	IFT27	PKD1	SCAPER	GLI3	IFT52	IFT57	IQCB1	FLCN	EFHC2	CEP164	OCRL	
MBDNF AND PROBDNF REGULATION OF GABA NEUROTRANSMISSION%WIKIPATHWAYS_20260910%WP4829%HOMO SAPIENS	mBDNF and proBDNF regulation of GABA neurotransmission	JAK2	GABRA1	GABRP	AP2B1	GABRA6	GABRA5	GABRA4	NGFR	GABRA3	GABRG1	PLCG1	PIK3R3	STAT3	RHOA	BDNF	SHC1-1	ROCK1	SLC12A5	CREM	CREB1	PTEN	AP2A1	PIK3CB	AP2A2	PIK3CG	GABRB3	GABRB2	NTRK2	GABRB1	PIK3R2	PIK3R1	PIK3CA	GABRG3;GABRG2	GABRE	GABRD	GABRQ	GABRA2	
HDAC6 INTERACTIONS IN THE CENTRAL NERVOUS SYSTEM%WIKIPATHWAYS_20260910%WP5426%HOMO SAPIENS	HDAC6 interactions in the central nervous system	ISG15	EP300	CTNNB1	CDC20	FUS	ERG	G3BP1	HSPA8	VIM	GRK2	ITIH4	PARK7	SHH	GSK3A	SNCAIP	HDAC6	MYD88	TUBA1C	PPP1CA	MAPK8	BAX	CTTN	MAPT	TUBB3;TUBB6	ACTR1A	BDNF	NR3C1	EP400	HDAC11	BCL2	RAD23B	PROM1	PRDX2	AKT1	MAP3K5	CYBB	MAP1LC3A	TUBA4A	SIRT2	MDH1	GSK3B	AURKA	KAT5	NDUFV1	MAPK1	RAC1	MAPK3	SGK3;C8orf44-SGK3	MIF	TUBA3E;TUBA3C-1	HSF1	TUBB4A;TUBB;TUBB8B;TUBB8	PRDX1	SGK1-1	CSNK2A2	STUB1	CSNK2B	APOE	VHL	ATP13A2	SNCA	DCTN1	SOD1	RHOT1	SP1	UBD	SMAD7	PRKN	HTT	HDAC9	PTK2B	DNAJA1-1	EGFR	BBIP1	SQSTM1	PRKCE	APC	POU5F1;POU5F1B	GRIA1	CFTR	HIF1A	GRIA2	PRKCZ	VCP-1	HSP90AA1	ELP3	DLG2	DLG4	DYNC1I2	MAPRE1-1	SMAD2;SMAD3	TPPP	MYH9	FOXP3	BIRC5	OPTN-1	MAP1B	PXN	KALRN	XRCC6	ATXN3	HSPB1	CCDC141	HSPA4	CNOT6	NEDD9	MIIP	ELP1	TARDBP	ARID3A	GARS1	
MTHFR DEFICIENCY%WIKIPATHWAYS_20260910%WP4288%HOMO SAPIENS	MTHFR deficiency	GRIN1	DNMT1	MTHFR	COMT	HNMT	DNMT3A	CHKA	DNMT3B	MARS1	BHMT	CYCS-1	GRIN2A	NDUFAF7	CHDH	PEMT	ASMT	CASP9	CHPT1	ALDH7A1	GRIN2D	PCYT1A	EHMT2	CASP3	EHMT1	
GENETIC CAUSES OF PORTO SINUSOIDAL VASCULAR DISEASE%WIKIPATHWAYS_20260910%WP5269%HOMO SAPIENS	Genetic causes of porto sinusoidal vascular disease	DGUOK	C4orf54	BEND6	DLL4	EFL1	SHCBP1	MAPK3	IBTK	ARHGAP31	EOGT	NOTCH1	SBDS	NOTCH4	KCNN3	NCF2	BTK	ESR1	EIF6	CDC42	COX4I2	NOX3	GTF2I	SP1	TLR9	TLR8	NCF1	NCF4	CYBA	RBPJ	CYBB	DOCK6	CYBC1	NFKB1	CXXC5	MAPK1	CHCHD2	RAC1	
EGFR TYROSINE KINASE INHIBITOR RESISTANCE%WIKIPATHWAYS_20260910%WP4806%HOMO SAPIENS	EGFR tyrosine kinase inhibitor resistance	JAK2	IL6R	EIF4EBP1	NRG2	PDGFD	MAPK3	JAK1	PDGFC	PLCG2	ERBB3	BAD	STAT3	GAB1	PDPK1	HGF	IL6	IGF1R	RRAS	RPS6KB1	GRB2	SOS1	BCL2L1	SHC4	EGF	SHC1-1	SHC2	SRC	GAS6	PDGFA	CCND1	TGFA	MYC	ERBB2	KDR	PDGFRA	PDGFB	PDGFRB	PTEN	FGF2	SOS2	EGFR	VEGFA	PRKCG	NRG1	IGF1	PRKCB	PRKCA	RPS6KB2	NRAS	PLCG1	PIK3R3	BAX	HRAS	NF1	EIF4E	KRAS	EIF4E2	BCL2	RAF1	MET	AXL	ARAF	FGFR3	FGFR2	FOXO3	PIK3CD	AKT2	RRAS2	BCL2L11	AKT3	MRAS	PIK3CB	AKT1	SHC3	MTOR	GSK3B	RPS6	PIK3R2	BRAF	PIK3CA	PIK3R1	MAP2K2;MAP2K1	MAPK1	
AMINO ACID METABOLISM%WIKIPATHWAYS_20260910%WP3925%HOMO SAPIENS	Amino acid metabolism	PC	CPS1	SMS	EHHADH-1	LDHA	SDS	HIBADH	PKM	TPO	OTC	MCCC1	PPM1L	IARS1	VARS1	AOC3	ACAA1-1	CBS;CBSL	AUH	SRM	MMUT	ACO2	G6PC2	BCAT1	DLD	HIBCH	SDHA	MARS2	PDHX	FH	TAT	DLST	HAL	FAH	GPT2	PDHA1	ACLY	SUCLG1	LARS2	CTH	CS	MDH2	PNMT	DDC	MAOA	GOT2-1	ALDH7A1	TDO2	EPRS1	GOT1-1	ACADM	HADH	GLUL	GLS	TPH1	FTCD	MPST	PYCR1	HMGCL	BHMT	RARS1	ADH4	ADH1C;ADH1B;ADH1A	GLUD1;GLUD2	ALDH1A1	IDH1	P4HA2	GSS	GSR	ALDH18A1	PDK4	DBH	ADH5	PCK1	HMGCS2	OGDH	GCLM	FARSB	HNMT	CAD	ACSS1	TH	MDH1	HDC	ARG2	ASNS	OAT	ARG1	WARS1	ODC1	ASS1	
GLUCOSE METABOLISM IN TRIPLE NEGATIVE BREAST CANCER CELLS%WIKIPATHWAYS_20260910%WP5211%HOMO SAPIENS	Glucose metabolism in triple negative breast cancer cells	SLC2A1	LDHA	PKM	PFKP	HK1	PDK1	PDP1	SLC16A1	
PERTURBATIONS TO HOST CELL AUTOPHAGY INDUCED BY SARS COV 2 PROTEINS%WIKIPATHWAYS_20260910%WP4936%HOMO SAPIENS	Perturbations to host cell autophagy induced by SARS CoV 2 proteins	ATG2B	DEPTOR	ATG16L1	VPS11	PKM	VPS16	VAMP8	TMEM59	ATG9A	LAMTOR1	VPS39	RHEB	RPS6KB1	RB1CC1	PRKAA2	VPS33A	PPP1R9A	APOB	CALCOCO2	RPTOR	EIF4B	ATG13	OPTN-1	LARP1-1	TAX1BP1	MLST8	ULK1	RAB7A	AKT1	LAMP2	MTOR	VPS41	ATG3	MAP1LC3B2;MAP1LC3B-1	GABARAPL2	RPS6	ATG12-1	NBR1	AKT1S1	SQSTM1	ATG4A	ATG7	ATG5	VPS18	
FACTORS AND PATHWAYS AFFECTING INSULIN LIKE GROWTH FACTOR IGF1 AKT SIGNALING%WIKIPATHWAYS_20260910%WP3850%HOMO SAPIENS	Factors and pathways affecting insulin like growth factor IGF1 Akt signaling	ILK	DEPTOR	PPARGC1A	IGFBP5	TNFRSF1A	IRS1	IGF1R	EIF4E	RPS6KB1	TNFSF9	ACVR2B	PLD1	SMAD2;SMAD3	EIF2B2	RPTOR	PRKAB1	NEB	MAPKAP1	FBXO32	MLST8	PDK1	PTEN	AKT1	MSTN	MTOR	PIK3CG	MAP1LC3A	TRIM63	GSK3B	RICTOR	ITGB1	IGF1	AKT1S1	NFKB1	WASL	
8P23 1 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5346%HOMO SAPIENS	8p23 1 copy number variation syndrome	MTMR8	MTMR9	MAPK3	MTMR6	MEPE	MTMR7	CTSB	TBX5	SLBP	TNKS	MCRS1	CSTA	PINX1	GATA4	RP1L1	HEPACAM2	CTNNB1	C8orf74	DEFB135	CGAS	CLDN23-1	FDFT1	MFHAS1	FAM167A	BMP1	XKR6	SLC35G4;SLC35G5;SLC35G3;SLC35G6	SOX7	SLC2A4	RAF1	TERF1-1	TERT	NUMA1	PPP1R3B	SGPL1	TLR2	BLK	ERI1	TLR4	NKX6-1	AXIN1	HSPD1	S100A10	CTSD	NEIL2	PDX1	MAPK1	MSRA	
GENES TARGETED BY MIRNAS IN ADIPOCYTES%WIKIPATHWAYS_20260910%WP1992%HOMO SAPIENS	Genes targeted by miRNAs in adipocytes	GJA1	PTBP2	HCN4	ERG	HAND2	KCNE1;KCNE1B	HCN2	KCNQ1	IGF1	KCNJ2	HDAC4	SRF	
EPITHELIAL TO MESENCHYMAL TRANSITION IN COLORECTAL CANCER%WIKIPATHWAYS_20260910%WP4239%HOMO SAPIENS	Epithelial to mesenchymal transition in colorectal cancer	DLL1	DLL3	DLL4	WNT11	WNT7B	FOXC2	MAPK14	MAPK12	MAPK13	MAPK11	LATS2	CTNNB1	MPP5	JUP	CLDN4	CLDN23-1	CLDN5	CLDN3	ITGA5	PDCD6	CDKL2	CLDN9	CLDN8	FN1	CLDN7	PKP1	EIF5A2	CLDN20	PAK1	CLDN22;CLDN24-1	CLDN10	CLDN15	PKP2	CLDN14	CLDN12	CLDN19	ID2-1	STRAP	CLDN18	CLDN17	CLDN16	CRB3	TP53	CLDN11	MAPK8	ZEB1	EZH2	TMPRSS4	MAP2K6	MAP2K3	TGFBR1-1	RAF1	CDH1	FZD1	FZD3	MEF2D	WNT3A	WNT5A	MMP15	WNT7A	PROX1	WNT3	LRP6	AKT2	AKT3	AKT1	GSK3B	CTDSP1	PIK3R2	TGFB2	PIK3R1	TGFB1	OCLN-1	TGFB3	MAP2K2;MAP2K1	MAPK1	TGFBR2	TRAF6	FOXQ1	MAPK3	MAP2K4	NR2C2	FMNL2	DSP	CDH2	SNAI1	SNAI2	MMP2	GRB2	MMP9	SOS1	SHC1-1	NRP2	CLDN6	CLDN2	COL4A2	COL4A1	SPARC	GDF15	COL4A4	FZD10	COL4A6	RBPJ	NUBPL	SOS2	VTN	WNT5B	NOTCH2	NOTCH3	NOTCH1	NOTCH4	HIF1A	PIK3R3	HRAS	WNT6	WNT1	WNT2	WNT4	JAG2	TJP1	WNT10B	WNT10A	ID1	KRAS	SMAD4	FZD2	CLDN1	JAG1	FZD5	FZD4	FZD7	FZD6	FZD9	SUZ12	SMAD2;SMAD3	FZD8	COL4A3	COL4A5	EED	TUSC3	WNT2B	PKD1	PIK3CD	TWIST2	PIK3CB	ZEB2	WNT9B	WNT9A	WNT16	PIK3CA	FOXM1	RBBP4	LRP5	WNT8A	WNT8B	DLK1	
PANCREATIC ADENOCARCINOMA PATHWAY%WIKIPATHWAYS_20260910%WP4263%HOMO SAPIENS	Pancreatic adenocarcinoma pathway	MAPK9	MAPK3	JAK1	RAC3	STAT1	BAD	PRKCD	STAT3	DUSP6	IKBKB	MAPK10	RB1	IKBKG	CHUK	CDKN1A	RPS6KB1	RELA	CASP9	PLD1	BCL2L1	EGF	CDC42	CCND1	TGFA	PAK1	ERBB2	PAK3	PEBP1	PAK2	PAK4	DDB2	RALGDS	BRCA2	RIPK4	PLD2	POLK	TP53	RALB	EGFR	E2F1	E2F2	E2F3	VEGFA	BAK1	GADD45B	GADD45A	GADD45G	RPS6KB2	CDK6	RAD51	CDK4	MAPK8	PIK3R3	BAX	RALBP1-1	RALA-1	KRAS	SMAD4	TGFBR1-1	BUB1B-PAK6;PAK6	RAF1	ARHGEF6	SMAD2;SMAD3	ARAF	PAK5	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	MTOR	CDKN2A	PIK3R2	TGFB2	BRAF	PIK3CA	PIK3R1	TGFB1	TGFB3	MAP2K2;MAP2K1	NFKB1	MAPK1	RAC1	TGFBR2	
LEUKOCYTE INTRINSIC HIPPO PATHWAY FUNCTIONS%WIKIPATHWAYS_20260910%WP4542%HOMO SAPIENS	Leukocyte intrinsic Hippo pathway functions	ITGAL	CD19	STK3	SAV1	YAP1-1	MAPK14	TEAD1	WWTR1	TEAD3	MOB1A;MOB1B	TEAD4	LATS2	RHOA	MST1	LATS1	FYB1	TEAD2	FOXO1-1	FOXO4	CCR7	STK38L	FOXP3	RASSF5	FOXO3	FOXO6	KNSTRN-1	YWHAQ	RAB13	FERMT3	RAP1A	NDRG1	PRDM1	LPL	RAC1	
COMPLEMENT SYSTEM%WIKIPATHWAYS_20260910%WP2806%HOMO SAPIENS	Complement system	ITGB3	C3-1	CFP	CD19	WAS	ICAM1	PROS1	FGB	ITGA2	FGA	C4BPA	ARRB2	C3AR1	LOC110384692;C4A;C4B_2;C4B	FGG	C5AR2	CR2	FCN2;FCN1	APOA1	PLAUR	PLG	LRP2	MASP2	MASP1	C5	CFB	C1QBP	CFD	C1S	SELPLG	IBSP	CFI	SPP1	C5AR1	SELE	CD59	SELP	C2	GNAI3	GNAI2	C6	F11	C7	ALB	C9	CD55	F10	PTX3	C8A	CR1L;CR1	VSIG4	CD93	DCN	CFH-3	CFHR1;CFHR2	FCER2	APCS	VTN	FKBP2	CLEC4M;CD209-2	CSNK1A1	PRKCA	FPR1	LAMC1	ICAM2	MBL2-1	F13A1	ADIPOQ	F12	ADM	SERPING1	LAMA5	ELANE	KLKB1	CPN1	CD40	ITGA2B	GNA15	PRKACA-1	RPS19	TLR2	LAMB1	PRNP	THBS1	CRP	FCGR3A;FCGR3B	CALR-1	TXN	SELL	
BURN WOUND HEALING%WIKIPATHWAYS_20260910%WP5055%HOMO SAPIENS	Burn wound healing	KLF4	COL1A1	COL1A2	ICAM1	CD3E	MMP1	HGF	IL6	SNAI2	MMP2	LGALS1	FBN1	MMP9	EGF	CASP3	CXCL8	TNC	TIMP1	HMGB1-1	PDGFRB	TLR4	TNF	IFNB1-4	IL15	TP53	DCN	SFRP2	HEXD	VEGFA	KRT222	PECAM1	CXCL2;CXCL3;CXCL1-1	S100A6	SCEL	S100A11	S100A9	AMBP	NOX4	SLURP1	TPT1	CDK16	MYD88	IL1B	BAX	LIN28A	F13A1	ACTA1	MMP28	CXCR4	CXCL12	ACHE	FOXE1	BCL2	SMAD2;SMAD3	CHRNA7;CHRFAM7A	FGFR4	FGFR3	FGFR2	SERPINH1	FGFR1	FST	BRD4	AKT1	CCL13;CCL2	INHBA	TGFB2	CXCR2	TGFB3	NFKB1	KRT6B;KRT6C;KRT6A	
LIVER X RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2874%HOMO SAPIENS	Liver X receptor pathway	SREBF1	NR1H3	CYP2B6	CYP7A1	SCD	RXRA	FASN	ABCG8	ABCG5	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
TRANSCRIPTION CO FACTORS SKI AND SKIL PROTEIN PARTNERS%WIKIPATHWAYS_20260910%WP4533%HOMO SAPIENS	Transcription co factors SKI and SKIL protein partners	HDAC3	ING2	SKIL	STK3	MECP2	MERTK	PRMT5	TEAD1	TEAD3	NF1	TEAD4	LATS2	LATS1	HDAC1	SIN3A	SKI	TEAD2	SATB2	
SARS COV 2 AND ACE2 RECEPTOR MOLECULAR MECHANISMS%WIKIPATHWAYS_20260910%WP4883%HOMO SAPIENS	SARS CoV 2 and ACE2 receptor molecular mechanisms	AGT	ACE2	TMPRSS2	ACE	AGTR1	MAS1	REN	
PHOSPHATIDYL INOSITOL PHOSPHATE PATHWAY%WIKIPATHWAYS_20260910%WP5411%HOMO SAPIENS	Phosphatidyl inositol phosphate pathway	PI4K2B	MTMR2	TPTE;TPTE2	MTMR8	PI4KB	PI4K2A	MTMR6	MTM1	PLCG2	PIP5K1A	PLCG1	PIP5K1B	PIP4K2A	PIP5K1C	PIKFYVE	PLCB3	PLCB4	PLCD3	PLCD4	PLCD1	IPMK	PLCB1	INPP5E	PLCB2	INPP4B	INPP5D	PI4KA	PTEN	PIK3CD	PIK3C2G	PIK3CB	PIK3C2A	PIK3CG	PIK3C2B	PIP4P2	INPP4A	PIP4P1	PLCE1	INPP5K	PIP4K2B	PIK3CA	PIP4K2C	SACM1L	OCRL	FIG4	MTMR1	
15Q11 2 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP4940%HOMO SAPIENS	15q11 2 copy number variation syndrome	CYFIP1	TUBGCP2	NIPA1	TUBGCP5	NIPA2	FMR1	TUBGCP6	TUBGCP3	TUBGCP4	
PANCREATIC CANCER SUBTYPES%WIKIPATHWAYS_20260910%WP5390%HOMO SAPIENS	Pancreatic cancer subtypes	SLC2A1	SPRR3	ST6GALNAC1	SERPINB3;SERPINB4-1	KRT20	CTSE	LGALS4	TFF3-1	VSIG2	AGR2	AGR3	FAM3D	LYZ-1	SPINK4	CDH17	KRT7	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	ANXA10	LEMD1	CEACAM8;CEACAM7;CEACAM6;CEACAM1;CEACAM5-1	KRT17	MYO1A	GPR87	PRR15L	LY6D	TFF1	VGLL1	CLRN3	DHRS9	CTSV;CTSL	AREG	FAM83A	TNS4	FGFBP1	REG4	SPRR1A;SPRR1B	ANXA8;ANXA8L1	PLA2G10;LOC100652777	S100A2	SCEL	TSPAN8	CST6	KRT15	KRT6B;KRT6C;KRT6A	
LUPUS PATHOGENESIS%WIKIPATHWAYS_20260910%WP5559%HOMO SAPIENS	Lupus pathogenesis	PDCD1	LOC102723996;ICOSLG	TNFRSF13C	CD40LG	TLR9	TLR7	TLR4	CD86	ICOS	CD274	CD80	TNFSF13B	IL6	BCR	CD28	CD40	IL17A	
COCAINE METABOLISM%WIKIPATHWAYS_20260910%WP2826%HOMO SAPIENS	Cocaine metabolism	CES2	BCHE	CES1	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	
TAR SYNDROME%WIKIPATHWAYS_20260910%WP5362%HOMO SAPIENS	TAR syndrome	PEX19	MTA1	CCAR2	STAT3	CD247	LAMTOR1	CD3D	UBE2I	FURIN	IFNG	SLC22A4	EGFR	HJV	HLA-C;HLA-B;HLA-A;HLA-G;HLA-F;HLA-E	CD160	DNM1	TNFRSF14	BCL2L13	HDAC2	CFTR	RBCK1	SIRT1	AKAP10	FARP2	CXCR4	ANKRD35	HAMP	EIF4A3	SLC22A12	SLK	SUMO2	PDZK1	GPR89A;GPR89B	PEX11B	MET	CLCN3	SLC9A3R1	LCK	MAGOH;MAGOHB	BRF1	PYM1	PDZK1IP1	MITD1	FLT3	POLR3GL	ZFHX3	POLR3C	POLR3F	POLR3G	PIAS3	ITGA10	ITGB1	DDIT4	NFKB1	TXN	
GNAQ P R183Q DRIVES CAPILLARY MALFORMATION%WIKIPATHWAYS_20260910%WP5501%HOMO SAPIENS	GNAQ p R183Q drives capillary malformation	PRKCA	PRKCQ	PPP3CA	PRKD1	NFATC1	PPP3CB	PPP3CC	PRKD3	PRKCD	PRKCZ	PLCB3	PKN3	ANGPT2	PKN2	PPP3R1	GNAQ	PKN1	PRKD2	PRKCG	PRKCI	PRKCH	RCAN1	PRKCB	PRKCE	
EXERCISE INDUCED CIRCADIAN REGULATION%WIKIPATHWAYS_20260910%WP410%HOMO SAPIENS	Exercise induced circadian regulation	GSTP1	NCOA4	PER2	UGP2	PER1	G0S2	IDI1	H2BC15;H2BC3;H2BC11;H2BC12	GSTM3	SF3A3	GFRA1	KLF9	PSMA4	NCKAP1	TUBB3;TUBB6	PURA	CLDN5	CLOCK	HLA-DMA	CEBPB	PPP2CB;PPP2CA	NR1D2	UCP3	HSPA8	PPP1R3C	PIGF	HERPUD1	EIF4G2	DAZAP2	BTG1	AZIN1-2	STBD1	SUMO3	ERC2	ETV6	RBPMS	ZFR	MYF6	DNAJA1-1	CBX3-1	ARNTL	TOB1	QKI	CRY2	TAB2	VAPA	CRY1	SUMO1	
GLYCINE METABOLISM%WIKIPATHWAYS_20260910%WP1495%HOMO SAPIENS	Glycine metabolism	MTHFR	SHMT1	SHMT2	
SARS CORONAVIRUS AND INNATE IMMUNITY%WIKIPATHWAYS_20260910%WP4912%HOMO SAPIENS	SARS coronavirus and innate immunity	IRF3	IFNAR2	JAK1	STAT2	STAT1	MAVS	TLR3	IFNB1-4	TYK2	IRF9	TICAM1	ACE2	IFNAR1	IFIH1	TBK1	TRAF3	IKBKE	DDX58	
INDUCTION OF AUTOPHAGY AND TOLL LIKE RECEPTOR SIGNALING BY GRAPHENE OXIDE %WIKIPATHWAYS_20260910%WP5336%HOMO SAPIENS	Induction of autophagy and toll like receptor signaling by graphene oxide	MYD88	MAP1LC3A	TRAF6	IRF3	IFNG	TLR9	TLR4	BECN1	TNF	NFKB1	IFNB1-4	
MACROPHAGE STIMULATING PROTEIN MSP SIGNALING%WIKIPATHWAYS_20260910%WP5353%HOMO SAPIENS	Macrophage stimulating protein MSP signaling	HK2	MAPK9	LDHA	MAPK14	PPARGC1A	ELK1	PDPK1	CPT1A	CTNNB1	FOS	CLDN5	RELA	PRKAA2	EGR1	FN1	SRC	SIX1	VIM	KDR	RPS6KA5	PDGFRB	TNF	IFNB1-4	TP53	MST1R	ABL1	ACTA2	CXCL2;CXCL3;CXCL1-1	IL1B	MAPK8	ZEB1	PARP1	DUSP4	RPS6KA3	RPS6KA1	ACACA	JUN	NR4A1	RAF1	CDH1	FZD1	KLK15	AKT1	SLPI	MTOR	RPS6KA4	CCL13;CCL2	SOCS1	GSK3B	RPS6	PIK3R1	TGFB1	OCLN-1	SOCS3	NFKB1	MAP2K2;MAP2K1	MAPK1	CXCL10	MAPK3	CSF3	CSF2	SP7	GAB1	DUSP6	DUSP1	PDCD4	CDH2	IL6	IGF1R	SNAI2	RPS6KB1	GRB2	MMP9	SHC1-1	IL10	CXCL8	IBSP	PDGFRA	COL4A1	PTEN	VEGFA	PRKCB	SLC2A1	PLCG1	MST1	TJP1	WNT10B	SMAD1	CLDN1	CRKL	NR0B2	SMAD2;SMAD3	SMAD9	SMAD5	FGFR1	ZEB2	HSPB1	NDRG1	PCNA	SMAD6	PTK2	FLT1	CXCL5;CXCL6	ITGB1	
NUCLEOTIDE EXCISION REPAIR%WIKIPATHWAYS_20260910%WP4753%HOMO SAPIENS	Nucleotide excision repair	CUL4A	ERCC3	ERCC4	POLE2	RPA3	ERCC1	POLE3	ERCC2	ERCC8	ERCC6	CUL4B	CDK7	MNAT1	CETN2	POLE	RFC5	RFC3	RFC4	RFC2	RAD23A	ERCC5;BIVM-ERCC5	RAD23B	RFC1	DDB1	GTF2H2C;GTF2H2C_2;GTF2H2	DDB2	POLD3	POLD4	CCNH	POLD1	POLD2	LIG1	PCNA	RBX1	RPA1	GTF2H1	GTF2H3	RPA2	XPA	GTF2H4	XPC	POLE4	
DISORDERS OF GALACTOSE METABOLISM %WIKIPATHWAYS_20260910%WP5173%HOMO SAPIENS	Disorders of galactose metabolism	GBE1	SLC2A2	PYGL	GYG2	PGM1	GALT	GYS2	GYS1	GALK1	GYG1	AKR1B1	GALE	SLC5A1-1	
2Q21 1 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5223%HOMO SAPIENS	2q21 1 copy number variation syndrome	CCDC42	STAT3	RHOA	AMER3	PLEKHB2	MZT2A;MZT2B	STMN2	FAM168B	CDC27	GPR148	APC	ARHGEF4	RAC1	
ARYL HYDROCARBON RECEPTOR PATHWAY%WIKIPATHWAYS_20260910%WP2873%HOMO SAPIENS	Aryl hydrocarbon receptor pathway	ALDH3A1	JUNB	IL1B	CES3	CAP2	AHRR	NCOA1	SERPINB2	MYOF	BAX	IL12B	HSP90AA1	CYP1A2	EP300	CDKN1B	SLC7A5	CYP1A1	JUN	AIP	JUND	SRC	GSTA3;GSTA5;GSTA1;GSTA2	IL2	NQO1	IFNG	IL12A	TNF	POLK	CDC37	UGT1A1;UGT1A6	NFE2L2	CYP1B1	IGFBP1	PTGES3-1	AHR	EGFR	HES1	TGFB1	ARNT	IL17B	MGST1	
PARKIN UBIQUITIN PROTEASOMAL SYSTEM PATHWAY%WIKIPATHWAYS_20260910%WP2359%HOMO SAPIENS	Parkin ubiquitin proteasomal system pathway	HSPA6	TUBA3E;TUBA3C-1	TUBB4A;TUBB;TUBB8B;TUBB8	TUBA8	TUBB2B;TUBB2A	STUB1	PSMD8	PSMD9	PSMD6	TUBAL3	PSMD7	PSMD4	PSMD2	SNCA	PSMD3	CUL1	HSPA8	PSMD1	PSMC2-1	PSMD5	CCNE1	PRKN	PSMD11	PSMD10	UBE2L6	UBE2J2	UBE2J1	CASP1	GPR37	HSPA9	SEPTIN5	UBE2G1	UBE2G2	FBXW7	SNCAIP	UBA1	HSPA2	TUBA1C	SIAH2	TUBA1A	CASK	CASP8	TUBB3;TUBB6	TUBB4B	PSMC5	PSMC6	PSMC3	PSMC4	PSMC1	SIAH1	TUBB1	TUBA4A	HSPA1A;HSPA1B	HSPA4	RNF19A	PSMD12	HSPA5	PSMD14	HSPA14	PSMD13	HSPA1L	
HYPOXIA MEDIATED EMT AND STEMNESS%WIKIPATHWAYS_20260910%WP2943%HOMO SAPIENS	Hypoxia mediated EMT and stemness	DICER1	ZEB1	
CANONICAL AND NON CANONICAL NOTCH SIGNALING%WIKIPATHWAYS_20260910%WP3845%HOMO SAPIENS	Canonical and non canonical Notch signaling	DLL1	PSEN1	DLL3	DLL4	MFAP1	NOTCH2	NOTCH3	NOTCH1	NOTCH4	CHUK	JAG2	RRAS	JAG1	DNER	MAML2	MAML1	RBPJ	LEF1	HEY1	HES1	DLK2	PSEN2	MFAP2	MAML3	CNTN6	ADAM10	DLK1	
METHYLATION PATHWAYS%WIKIPATHWAYS_20260910%WP704%HOMO SAPIENS	Methylation pathways	TPMT	MAT2A	PNMT	COMT	HNMT	MAT1A	MAT2B	INMT	NNMT	
TCA CYCLE AKA KREBS OR CITRIC ACID CYCLE %WIKIPATHWAYS_20260910%WP78%HOMO SAPIENS	TCA cycle aka Krebs or citric acid cycle	DLST	OGDH	SUCLA2	SUCLG2	SUCLG1	IDH2	IDH3A	CS	MDH2	ACO2	SDHC	SDHD	DLD	SDHA	SDHB	IDH3G	IDH3B	FH	
PDGF PATHWAY%WIKIPATHWAYS_20260910%WP2526%HOMO SAPIENS	PDGF pathway	RASA1	MAPK3	JAK1	MAP2K4	MAPK8	PLCG1	STAT1	HRAS	STAT3	ELK1	PLA2G4A	PTPN11	CHUK	RHOA	VAV1	ARFIP2	VAV2	FOS	GRB2	JUN	MAP3K1	SOS1	NFKBIA	SHC1-1	SRC	PDGFA	CDC42	RAF1	PAK1	TIAM1	PDGFB	PDGFRB	PIK3R1	MAP2K2;MAP2K1	NFKB1	MAPK1	SRF	WASL	RAC1	
MODULATION OF PI3K AKT MTOR SIGNALING BY BIOACTIVE SPHINGOLIPIDS%WIKIPATHWAYS_20260910%WP5192%HOMO SAPIENS	Modulation of PI3K Akt mTOR signaling by bioactive sphingolipids	ASAH2	HIF1A	AKT1	MTOR	TSC1	S1PR1	S1PR3	CERK	IGF1R	CERS1	SPHK2	PIK3CA	PLD1	NFKB1	
FLUOROPYRIMIDINE ACTIVITY%WIKIPATHWAYS_20260910%WP1601%HOMO SAPIENS	Fluoropyrimidine activity	TK1	SMUG1	CES2	ABCG2	CES1	CYP2A13;CYP2A6;CYP2A7-1	TYMS	ERCC2	RRM1	UCK1	DHFR2;DHFR	ABCC3	ABCC4	ABCC5	RRM2-1	SLC29A1	GGH	MTHFR	DPYS	UPB1	TYMP	UMPS	DPYD	TDG	TP53	XRCC3	PPAT	CDA	FPGS	SLC22A7	UPP1	
CHOLESTEROL BIOSYNTHESIS PATHWAY%WIKIPATHWAYS_20260910%WP197%HOMO SAPIENS	Cholesterol biosynthesis pathway	SQLE	IDI1	CYP51A1	MVK	NSDHL	SC5D	MSMO1	DHCR7	MVD	HMGCR	HMGCS1-1	PMVK	FDFT1	FDPS	LSS	
HEROIN METABOLISM%WIKIPATHWAYS_20260910%WP2645%HOMO SAPIENS	Heroin metabolism	CES2	BCHE	CES1	
PHYSICO CHEMICAL FEATURES AND TOXICITY ASSOCIATED PATHWAYS%WIKIPATHWAYS_20260910%WP3680%HOMO SAPIENS	Physico chemical features and toxicity associated pathways	ACTR3-1	WNT11	MAP2K4	NEFM	NEFH	ERBB4	ELK1	CTNNB1	CDKN1A	CDKN1B	CBL	GRB2	SOS1	PFN1	STAT5A	SHC1-1	FN1	ROCK2	SRC	DVL1	TGFA	PAK1	MYLK	MYC	ERBB2	SOD1	ACTR2	CAMK1	FZD10	AXIN1	EGFR	DAAM1	MYL1	APC	GRIA1	PFN3	MAPK8	PLCG1	RHOA	GPX1	ACTA1	FZD2	JUN	FZD5	NCK1	FZD4	FZD7	PPP2CB;PPP2CA	NEFL	FZD6	FZD9	RAF1	FZD8	FZD1	NOS1	FZD3	AKT1	PIK3CG	GSK3B	WNT16	PTK2	MAP2K2;MAP2K1	MAPK1	PFN2-1	
LAC PHE PATHWAY%WIKIPATHWAYS_20260910%WP5239%HOMO SAPIENS	Lac Phe pathway	CNDP2	ABCC5	
KCNQ2 RELATED EPILEPSIES%WIKIPATHWAYS_20260910%WP5360%HOMO SAPIENS	KCNQ2 related epilepsies	PRKCA	PRKACA-1	CHRM1	ANK3	PPP3CC	P2RY1	PLCG2	SCN1B	BACE1	KCNQ2	KCNQ3	STX1A	CSNK2A1;CSNK2A3	AGTR1	BDKRB2	PPP1R10	AKAP5	ITPR1	CALM1	
N GLYCAN BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP5153%HOMO SAPIENS	N glycan biosynthesis	MGAT4A-1	MAN1A2	GMPPA	MAN1A1	ST6GAL1	ST6GAL2	ALG5	DAD1	MAN1B1	GANAB	MAN2A2	MAN2A1	MGAT5	MAN1C1	MGAT3	MGAT5B-1	MGAT4C	MGAT4D	DOLPP1	MGAT4B	STT3A	DDOST	STT3B	ALG10;ALG10B	B4GALT3	RFT1	RPN2	RPN1	B4GALT2	GPI	FUT8	DPM2	MGAT1	DPAGT1	ALG8	ALG9	B4GALT1	ALG6	TUSC3	MPI	PMM2	SRD5A3	ALG2	ALG14	ALG3	DOLK	MOGS	ALG12	ALG1	ALG11	DPM1	GMPPB	DPM3	MGAT2	MPDU1	
UREA CYCLE AND ASSOCIATED PATHWAYS%WIKIPATHWAYS_20260910%WP4595%HOMO SAPIENS	Urea cycle and associated pathways	GOT1-1	GPT	CPS1	NOS2	ALDH4A1	LDHB	GLS2	ASL	NAGS	NOS1	SLC25A12	SLC25A13	OTC	NOS3	PYCR1	MDH2	GLUD1;GLUD2	MDH1	GOT2-1	OAT	ARG1	SLC25A15	FH	ASS1	
SOLUBLE ACE2 MEDIATED CELL ENTRY OF SARS COV 2%WIKIPATHWAYS_20260910%WP5076%HOMO SAPIENS	Soluble ACE2 mediated cell entry of SARS CoV 2	ACE2	AGTR1	ADAM17	AVPR1B	
CALCIUM REGULATION IN CARDIAC CELLS%WIKIPATHWAYS_20260910%WP536%HOMO SAPIENS	Calcium regulation in cardiac cells	ITPR2	ADCY8	ATP2B1	GJA1	RYR1	ORAI1	CASQ1	PRKACB-1	PRKAR2B	CACNB1	PRKAR2A	CACNB3	PRKAR1B	PRKAR1A	GNAI3	GNAI2	CAMK1	YWHAE	GNB5	YWHAB	YWHAQ	GNAO1	YWHAH	ADCY1	SFN	GJA4	CALM1	CALM2	RYR3	CACNA1B	CHRM1	CACNA1A	PLCB3	ATP2B3	ATP2B2	ADRA1A	GJB1	RGS1	CALM3;CALM1	RGS2	ANXA6	GRK6	GJA3	YWHAG	GJA5	CALR-1	YWHAZ	KCNJ5	GJA8	ITPR1	CACNA1D	ITPR3	CACNA1C	RGS4	RGS5	RGS3	RGS6	RGS7	GNG13	GNA11	GRK5	GRK4	PRKCD	CACNA1S	PKIB	PKIA	GNGT1	PKIG	GJB6	RGS18	ARRB1	RGS17	GJC2	ATP2A3	ARRB2	ATP2A2	RGS19	RGS14	RGS16	RGS20	GJA9	STIM2	RGS10	GJC1	ADCY4	CHRM4	GJB4	ADCY2	RGS11	CHRM5	GJB3	ADRB1	GJB5	RGS9	ADRA1D	GJD2	ADCY7	CASQ2	ADCY6	ATP1A4	CHRM2	KCNB1	ADCY5	ATP1B3-1	SLC8A3	ATP1B1	SLC8A1	ADCY9	PRKCG	PRKCH	FXYD2;FXYD6-FXYD2	PRKCB	GNB2	PRKCE	PRKCA	GNB1	ADRB2	GNB4	GNB3	ADCY3	PRKCQ	CAMK2B	PRKD1	RYR2	GNAI1	CAMK2D	CAMK2A	PRKCZ	GJB2	CAMK2G	GNAS-1	GNAQ	GNAZ	ADRA1B	GNG2	GNG5	KCNJ3	GNG4	PRKACA-1	GNG8	CAMK4	CHRM3	ATP1B2	FKBP1A	ADRB3	CACNA1E	
NUCLEAR RECEPTORS META PATHWAY%WIKIPATHWAYS_20260910%WP2882%HOMO SAPIENS	Nuclear receptors meta pathway	SLC5A6	ALDH3A1	APOA5	SLC5A9	CES3	CES2	EPHA3	SLC5A3	SLC5A5	ANGPTL4	CES5A	SLC5A4	RXRA	PLTP	PRDX6	SLC6A5	SLCO2B1	IP6K3	SLC2A9	PPARGC1A	SLC6A7	SLC6A19	SLC6A8	MAFF	EP300	SLC2A5	SLC2A6	SLC2A7	SLC2A8	SLC2A11	SLC2A10	ABCC5	SLC2A13	SLC39A11	SLC39A10	SLC39A13	SLC39A12	SLC39A14	SLC5A11	SLC5A12	ESR1	SLC5A10	CBR3	TXNRD3	CCND1	MYC	NRIP1	PDGFB	TNF	FKBP5	SPRY1	DNAJC7	IL1B	FTL-1	CYP1A2	CYP3A4;CYP3A7-CYP3A51P;CYP3A7-2	G6PD	BLVRB	NR3C1	JUN	GSR	GSTT2B;GSTT2	GSTM1;GSTM2-1	SLC27A1	GSTA3;GSTA1	ABCG8	GCLC	CPT2	ABCG5	ME1	GSTA3;GSTA5;GSTA1;GSTA2	AKAP13	GCLM	EPB41L4B	GGT1	APOC3	ARL5B	SMARCA1	FABP1	PSMC5	RGS2	ENC1	TNS4	SRGN	SCD	FGFBP1	EDN2	TSC22D3	SERPINB9	NAV3	ADGRF4	CDC42EP3	SCNN1A	CYP1B1	PMP2	MFGE8	SULT1A2;SULT1A1;SULT1A4;SULT1A3-1	PTGES3-1	SLC26A2	ABHD2	PRRG4	SEC14L1	GPR153	SERTAD2	SULT2A1-4	STOM	PPP1R14C	CAVIN2	MGST3	PLK2	EPHA2	MGST1	DNAJC15	MGST2	KTN1	S100P	CPEB4	DNAJB1	JUNB	AGER	CYP2B6	NCOA1	HBEGF	TXNRD1	GSTM4	STAT3	GSTM3	PRDX1	CYP4F3;CYP4F2;CYP4F12;CYP4F11	KEAP1	SLC7A11	MAFG	CYP1A1	SLC7A5	UGT2B11;UGT2B10;UGT2B28;UGT2B4;UGT2B7;UGT2B15;UGT2B17-1	SRPX2	SLC6A18	IL2	SLC5A8	IFNG	SP1	FGF19	IL12A	CYP2C9;CYP2C19	POLK	UGT1A1;UGT1A6	NCOA3	IGFBP1	SLC5A2	SLC19A2	EGFR	SLC6A20	BAAT	HES1	ABCB1	ACADM	GSTP1	AHRR	FGF13	CYP7A1	SLC6A11	HSP90AB1	CYP2A13;CYP2A6;CYP2A7-1	SLC2A2	CBR1-1	ETNK2	VDR	HSP90AA1	CYP8B1	GSTA4	SLC5A1-1	TNFAIP3	SLC2A4	THBD	PTPA	DNER	SCP2	AMIGO2	TXN	EHHADH-1	LRRC8A	PTGR1-1	NCOA6	ACAA1-1	ACOX1	CPT1A	PPARD	CDKN1B	AIP	EGR1	JUND	SRC	CUL1	SMC1A	BIRC2	BIRC3	IL11	NCOA2	CCL20	PPARA	GADD45B	CAP2	NR1H3	CDK4	CDK1	SLC6A9	MYOF	BAX	ABCC3	SREBF1	ABCC4	ABCC2	IRS2	FOXO1-1	SLCO1B3;SLCO1B3-SLCO1B7;SLCO1B7;SLCO1B1	FASN	SLC27A5	SLC6A1	SLC6A2	SLC6A3	SLC6A4	KAT2B	KLK15	SLC5A7	CCL13;CCL2	BHLHE40	TGFB2	TGFB1	ARNT	IL17B	NFKB2	TGFBR2	ZIC2	ANKRD1	SRXN1	CES1	SERPINA1	SLC2A12	IL12B	ABCB4	SLC10A1	HGF	NR1I3	SNAI2	CDKN1C	NR1I2	APOA1	NR1H4	ABCB11	TGFA	PDE4B	GCC1	SOD3	HMOX1	SLC6A6	B3GNT5	NFE2L2	SLC39A2	SLC39A1	SLC39A4	AHR	SLC39A3	NRG1	SQSTM1	SLC2A1	POU5F1;POU5F1B	SERPINB2	ALAS1	ALOX5AP	PTGS2-2	ACKR3-2	NR0B2	GPAM	PDK4	PCK1	NQO1	CDC37	TGFBR3	HSPA1A;HSPA1B	SLC39A9	FTH1	FGD4	SLC39A6	SLC39A5	SLC39A8	SLC39A7	SLC6A17	SLC6A16	SLC6A15	SLC6A14	APOA2	SLC6A13	PGD	
OPIOID RECEPTOR PATHWAYS%WIKIPATHWAYS_20260910%WP5093%HOMO SAPIENS	Opioid receptor pathways	RGS4	OPRL1	ADCY8	CACNA1B	DNMT3A	ALDH9A1	PGM1	GATA4	TUBB4A;TUBB;TUBB8B;TUBB8	JUP	ARC	RELA	BDNF	RGS9	HSPA8	NOS2	NEU2	RPLP2	HMOX1	OPRM1	GNAI2	TLR4	TNF	PIK3CG	GNA12	MBP	ADCY1	E2F1	HDAC1	MAP1LC3B2;MAP1LC3B-1	PRKCG	SQSTM1	RAC1	PRKCE	
LUPUS THERAPIES%WIKIPATHWAYS_20260910%WP5560%HOMO SAPIENS	Lupus therapies	C3-1	MS4A1	IL6R	C1QC	CD19	IL12B	TNFSF13B	LOC110384692;C4A;C4B_2;C4B	IL6	CD40	IL25	C1QB	CD22	IFNG	IL23A	C2	CD40LG	IL12A	CD86	CD80	CD38	IL17D	CD28	IL17C	IL17F	IL17B	IL17A	
IL23 INHIBITORS IN INFLAMMATORY BOWEL DISEASE%WIKIPATHWAYS_20260910%WP5516%HOMO SAPIENS	IL23 inhibitors in inflammatory bowel disease	JAK2	IL12RB1	CSF2	IFNG	IL23A	STAT1	STAT3	TLR4	TNF	IL12B	TYK2	IL22	RORC	STAT5A	STAT5B	IL17F	IL17A	STAT4	
TESSADORI BICKNELL VAN HAAFTEN SYNDROME 3 OVERVIEW PATHWAY%WIKIPATHWAYS_20260910%WP5575%HOMO SAPIENS	Tessadori Bicknell van Haaften syndrome 3 overview pathway	MED27	TAF8	MED23	TBP	TAF2	TAF13	H4C1	
NEURAL CREST CELL MIGRATION IN CANCER%WIKIPATHWAYS_20260910%WP4565%HOMO SAPIENS	Neural crest cell migration in cancer	SORT1	KIDINS220	NGFR	CDH11	PIK3R4	PIK3R3	STAT3	PIK3R6	PIK3R5	RHOA	FOS	MMP2	BDNF	TRIO	JUN	MMP9	EPHB6	EPHB1	EPHB3	NGEF	MMP8	BUB1B-PAK6;PAK6	PAK1	PAK5	PAK3	PAK2	PAK4	TIAM1	EPHB2	PIK3CD	AKT2	AKT3	PIK3CB	AKT1	EPHB4	F2RL2	PIK3CG	NTRK2	PIK3CA	ARF1	RAC1	
GDNF SIGNALING%WIKIPATHWAYS_20260910%WP5143%HOMO SAPIENS	GDNF signaling	FMOD	
1P36 COPY NUMBER VARIATION SYNDROME%WIKIPATHWAYS_20260910%WP5345%HOMO SAPIENS	1p36 copy number variation syndrome	DLL1	MCM2	ARF6	INTS4	C1QTNF12	ISG15	PLCH2	TRAF2	CALML6	LRP4	ESR1	DVL1	DLST	HSPA8	INTS11	PANK4	INTS13	INTS14	B3GALT6	INTS10	GDE1	CDK11A;CDK11B	TMEM52	NOC2L	OR4F21;OR4F16;OR4F29;OR4F3	METTL14	SDF4	CCNL2	PLEKHN1	UBE2J2	SAMD11	MUSK	VTN	ATAD3A;ATAD3B	OR4F5;OR4F17;OR4F4	RBX1	SSU72	VEGFA	PEX2	ACAP3	HES5	SCNN1D	RER1	GABRD	CD160	CPTP	PEX5	MXRA8	VWA1	TNFRSF14	PEX12	GNB1	AURKAIP1	PARD6B	PERM1	TNFRSF18	MEPCE	KLHL17	PUSL1	TAS1R3	HES4	TNFSF18	TNFRSF4	CFAP74	BTLA	MIB2	RNF223	ELAVL1	PRKCZ	PEX10	MORN1	FNDC10	GRIK2	ANKRD65	INTS9	SLC35E2B	KRT17	C1orf159	CUL3	DKK3	TNFSF4	TRAF5	SMAD4	MRPL20	SMAD2;SMAD3	MMP23B	IFIT1	AGRN	PHKG2	COMMD1	IFIH1	NADK	SKI	TGFB1	TRIM25	
SPHINGOLIPID METABOLISM OVERVIEW%WIKIPATHWAYS_20260910%WP4725%HOMO SAPIENS	Sphingolipid metabolism overview	PLPP2	SGMS1	DEGS2	ASAH1	CERS3	CERS6	CERK	CERS1	SPHK2	SPHK1	SGPL1	SGPP2	PLPP1	SPTLC1	GBA	SGMS2	GBA2	UGT8	UGCG	KDSR	CERS4	SGPP1	DEGS1	CERS2	SMPD1	PLPP3	
CALORIC RESTRICTION AND AGING%WIKIPATHWAYS_20260910%WP4191%HOMO SAPIENS	Caloric restriction and aging	SIRT1	MTOR	PRKAB2	NAMPT	IGF1	PPARGC1A	AKT1	TP53	
TROP2 REGULATORY SIGNALING%WIKIPATHWAYS_20260910%WP5300%HOMO SAPIENS	TROP2 regulatory signaling	JAK2	PRKCA	RACK1	CDK4	CDK2	NOTCH1	IGF2	STAT1	PRKCD	BAX	IGF2R	CTNNB1	RB1	TACSTD2	CDKN1B	MDK	IGF1R	ACVRL1	ITGA5	CLDN1	JUN	FN1	BCL2	CLDN7	SRC	CHEK1	ABCC1	CCND1	CDH1	MMP13	PAK4	VIM	PTEN	CCNE1	TLN1	EGFR	CDKN2A	PIK3R1	PTK2	PECAM1	PSEN2	ITGB1	IGF1	NFKB1	RAC1	
METABOLISM OF ALPHA LINOLENIC ACID%WIKIPATHWAYS_20260910%WP4586%HOMO SAPIENS	Metabolism of alpha linolenic acid	ALOX15	ALOX12	FADS2	PTGS2-2	FADS1	ALOX5	
TNF RELATED WEAK INDUCER OF APOPTOSIS TWEAK SIGNALING%WIKIPATHWAYS_20260910%WP2036%HOMO SAPIENS	TNF related weak inducer of apoptosis TWEAK signaling	MAP3K7	MAPK9	MAPK3	NFKBIB	MAPK8	CASP8	MAPK14	IKBKB	RIPK1	FADD	CTNNB1	CHUK	TRAF5	RELA	TRAF1	TRAF2	JUN	TRAF3	NFKBIA	CASP3	RAF1	BIRC2	BIRC3	TNF	AKT2	AKT1	TRIM63	TNFRSF12A	GSK3B	CASP7	HDAC1	RELB	NFKB1	MAPK1	NFKB2	RAC1	MAP3K14	
MIRNA REGULATION OF P53 PATHWAY IN PROSTATE CANCER%WIKIPATHWAYS_20260910%WP3982%HOMO SAPIENS	miRNA regulation of p53 pathway in prostate cancer	APAF1	SERPINE1	DDB2	SESN3	CASP8	BAX	PTEN	SIAH1	ATM	TNFRSF10C;TNFRSF10D;TNFRSF10B;TNFRSF10A	TP53	MDM2-2	SHISA5	CYS1	EI24-1	BBC3	PMAIP1	CASP9	BID	CHEK2	ZMAT3	CASP3	PERP	
CHROMOSOMAL AND MICROSATELLITE INSTABILITY IN COLORECTAL CANCER %WIKIPATHWAYS_20260910%WP4216%HOMO SAPIENS	Chromosomal and microsatellite instability in colorectal cancer	MAPK9	MAPK3	RAC3	BAD	MAPK10	CTNNB1	CDKN1A	FOS	BBC3	CASP9	CASP3	TCF7	APPL1	CCND1	MYC	DDB2	RALGDS	POLK	APC2	TP53	AXIN1	CYCS-1	AXIN2	DCC	LEF1	RALB	PMAIP1	MSH6	BAK1	MSH2	NTN1	TCF7L2	GADD45B	MSH3	TCF7L1	GADD45A	CSNK1A1	GADD45G	APC	MAPK8	BAX	RHOA	RALA-1	EXOC2	KRAS	PTGS2-2	SMAD4	JUN	TGFBR1-1	BCL2	RAF1	SMAD2;SMAD3	ARAF	BIRC5	AKT2	BCL2L11	AKT3	AKT1	REL	GSK3B	TBK1	TGFB2	BRAF	TGFB1	TGFB3	MAP2K2;MAP2K1	MLH1	MAPK1	RAC1	TGFBR2	
NOTCH1 REGULATION OF ENDOTHELIAL CELL CALCIFICATION%WIKIPATHWAYS_20260910%WP3413%HOMO SAPIENS	NOTCH1 regulation of endothelial cell calcification	DLL1	LPAR1	DLL3	MGP	DLL4	FGFR3	NOTCH1	ALPL	PLAT	SAT1	ITGA1	JAG2	SOX6	VEGFA	JAG1	GJA5	CALU	
COMPLEMENT AND COAGULATION CASCADES%WIKIPATHWAYS_20260910%WP558%HOMO SAPIENS	Complement and coagulation cascades	C3-1	C1QC	SERPINA1	SERPINE1	PLAT	PLAU	PROS1	CLU	FGB	SERPINA5	C8G	C3AR1	LOC110384692;C4A;C4B_2;C4B	CR2	SERPINF2	PLAUR	F2	F3	F7	F5	F8	PLG	F9	MASP2	MASP1	CFB	CFD	C1QB	CPB2	C1S	C1R	SERPINC1	CFI	C5AR1	TFPI	C2	LMAN1	F2R	C6	CLTC	C7	C9	CD55	F10	SERPIND1	CR1L;CR1	PROC	F13B	CFH-3	KNG1	VWF	F12	SERPING1	KLKB1	THBD	BDKRB1	
FOLLICLE STIMULATING HORMONE FSH SIGNALING%WIKIPATHWAYS_20260910%WP2035%HOMO SAPIENS	Follicle stimulating hormone FSH signaling	PRKCA	RPS6KB2	RAF1	EIF4EBP1	MAPK3	PRKACA-1	TSC2	H3C10;H3C8;H3C6;H3C1;H3-4;H3C3;H3C4;H3C7	CREB1	MAPK14	AKT1	MTOR	SGK1-1	RHEB	FSHB	RPS6KB1	GRK6	RPS6	FOXO1-1	MAPK1	CGA	SRC	FSHR	APPL1	
ACRYLAMIDE BIOTRANSFORMATION AND EXPOSURE BIOMARKERS%WIKIPATHWAYS_20260910%WP4233%HOMO SAPIENS	Acrylamide biotransformation and exposure biomarkers	CYP2E1	
NON CLASSICAL ROLE OF VITAMIN D%WIKIPATHWAYS_20260910%WP5133%HOMO SAPIENS	Non classical role of vitamin D	AGT	ACE2	CYP2R1	ACE	CYP27B1	AGTR1	AGTR2	REN	
THIAMINE METABOLIC PATHWAYS%WIKIPATHWAYS_20260910%WP4297%HOMO SAPIENS	Thiamine metabolic pathways	OGDH	BCKDHA	PDHA1	TKT	SLC19A2	BCKDK	TPK1	SLC25A19	SLC19A3	
TARGETED AGENTS IN TRIPLE NEGATIVE BREAST CANCER%WIKIPATHWAYS_20260910%WP5215%HOMO SAPIENS	Targeted agents in triple negative breast cancer	EIF4EBP1	DEPTOR	MAPK3	NRAS	AR	TELO2	HRAS	PARP1	IRS1	RPS6KB1	KRAS	INPP4B	GRB2	PRR5L	SOS1	PARP2	RAF1	ARAF	RPTOR	TSC2	MAPKAP1	MLST8	PDK1	PTEN	AKT2	AKT3	AKT1	MTOR	TSC1	SOS2	RICTOR	BRAF	PIK3R1	PIK3CA	AKT1S1	MAP2K2;MAP2K1	MAPK1	
PKC GAMMA CALCIUM SIGNALING IN ATAXIA%WIKIPATHWAYS_20260910%WP4760%HOMO SAPIENS	PKC gamma calcium signaling in ataxia	GNA14	GNA15	RYR3	GRIA1	GRIA3	GRIA4	CACNA1A	GNA11	HOMER3	GRIA2	PDK1	GRM1	PLCB3	ATP2B2	PLCB4	GNAQ	PLCB1	PLCB2	PRKCG	TRPC3	CA8	ITPR1	
REGULATION OF CYTOTOXIC T CELL RESPONSES BY MALAT1 MIR 15 16 CIRCUIT %WIKIPATHWAYS_20260910%WP5489%HOMO SAPIENS	Regulation of cytotoxic T cell responses by Malat1 miR 15 16 circuit	CD247	CD80	SPN	CD27	IL2	CD3D	CD28	CD3G	BCL2	CD3E	CD86	
DEREGULATION OF RAB AND RAB EFFECTOR GENES IN BLADDER CANCER%WIKIPATHWAYS_20260910%WP2291%HOMO SAPIENS	Deregulation of Rab and Rab effector genes in bladder cancer	SYTL4	UNC13D	SYTL3	RAB27B	SYTL2	TBC1D10A	EXPH5	MADD	RAB27A	RPH3A	MLPH	RPH3AL	SYTL1	GCC2	MYRIP	SYTL5	
NEPHROGENESIS%WIKIPATHWAYS_20260910%WP5052%HOMO SAPIENS	Nephrogenesis	FGF20	TCF21	NOTCH2	WNT3A	GREB1L	SIX2	RSPO3	RSPO1	BMP7	FOXD1	OSR1	WNT4	PAX2	WNT9B	FGF8	ALDH1A2	JAG1	MEIS1	
EFFECT OF INTESTINAL MICROBIOME ON ANTICOAGULANT RESPONSE OF VITAMIN K ANTAGONISTS%WIKIPATHWAYS_20260910%WP5273%HOMO SAPIENS	Effect of intestinal microbiome on anticoagulant response of vitamin K antagonists	PPARA	SCARB1	NR1I2	CD36	NPC1L1	CYP2C9;CYP2C19	VDR	PPARD	
INTERACTOME OF POLYCOMB REPRESSIVE COMPLEX 2 PRC2 %WIKIPATHWAYS_20260910%WP2916%HOMO SAPIENS	Interactome of polycomb repressive complex 2 PRC2	BCLAF1	SETX	JARID2	MORC3	ELL	EED	STK38	TRIM35	EZH2	AEBP2	MTF2	EZH1	RBBP7	RBBP4	THRAP3	SUZ12	
DIFFERENTIATION OF WHITE AND BROWN ADIPOCYTE%WIKIPATHWAYS_20260910%WP2895%HOMO SAPIENS	Differentiation of white and brown adipocyte	BMP4	BMP2	PRDM16	PPARGC1A	LEP	SLC7A10	CEBPA	SMAD1	ADIPOQ	CEBPB	PPARGC1B	SMAD9	ZIC1	SMAD5	HSPB7	BMP7	HOXC9	MPZL2	CEBPG	EBF3;EBF1	HOXC8	ZNF423	CIDEA	PPARG	PLAC8	
EICOSANOID METABOLISM VIA CYTOCHROME P450 MONOOXYGENASES PATHWAY%WIKIPATHWAYS_20260910%WP4720%HOMO SAPIENS	Eicosanoid metabolism via cytochrome P450 monooxygenases pathway	CYP4F3;CYP4F2;CYP4F12;CYP4F11	CYP2C18-1	PPARA	PPARG	EPHX2	
COMMON PATHWAYS UNDERLYING DRUG ADDICTION%WIKIPATHWAYS_20260910%WP2636%HOMO SAPIENS	Common pathways underlying drug addiction	PRKCA	GRIA1	MAPK3	ADCY8	GNAI1	GRIA3	PPP1CA	ACTC1;ACTG2	GRIA4	CAMK2A	GRM5	GRIA2	GRM1	PPP1CB	PPP1CC	GNAS-1	ACTG1	PRKACB-1	GJB1	RAF1	ARAF	GRIN1	PPP1R1A	PRKACA-1	DRD1	DRD2	CREB1	DRD4	CAMK4	ACTB-1	RAP1B	GRIN2A	RAP1A	ADCY1	PRKCG	MAP2K2;MAP2K1	CALM1	MAPK1	PRKCB	
WNT SIGNALING IN KIDNEY DISEASE%WIKIPATHWAYS_20260910%WP4150%HOMO SAPIENS	Wnt signaling in kidney disease	MAPK9	WNT11	MAPK8	WNT7B	MAPK10	WNT6	WNT1	CTNNB1	WNT2	RHOA	WNT4	WNT10B	WNT10A	NPHP3	FZD2	FZD5	FZD4	FZD7	FZD6	DVL1	FZD9	DVL2	FZD8	DVL3	FZD1	FZD3	WNT3A	WNT5A	WNT7A	WNT2B	WNT3	LRP6	WNT9B	WNT16	LRP5	WNT5B	INVS	
AMPK REGULATION OF MAMMARY MILK PROTEIN SYNTHESIS%WIKIPATHWAYS_20260910%WP5492%HOMO SAPIENS	AMPK regulation of mammary milk protein synthesis	PRKAB2	RPTOR	PRKAB1	PRKAA1	TSC2	MLST8	CSN1S1	MTOR	EIF4G1	EIF4A2	RPS6KB1	EIF4E	EEF2K	PRKAA2	PRKAG1	PRKAG2	CSN2-1	CSN3	PRKAG3	EEF2	
GASTRIC CANCER NETWORK 1%WIKIPATHWAYS_20260910%WP2361%HOMO SAPIENS	Gastric cancer network 1	S100P	H3-3A	UBE2C	NOTCH1	ACTL6A	RNF216	CENPF	CCNA1	MCM4	CEP192	TOP2A	RUVBL1	INO80D	KIF15	ESM1	MYBL2	ECT2	TPX2	H4-16	SMOC2	GATD3B;GATD3A	NUP107	LIN9	KIF20B	AURKA	E2F7	APC	
VITAMIN K METABOLISM AND ACTIVATION OF DEPENDENT PROTEINS%WIKIPATHWAYS_20260910%WP5186%HOMO SAPIENS	Vitamin K metabolism and activation of dependent proteins	PROC	NQO1	F2	F7	VKORC1	VKORC1L1	AIFM2	F9	GGCX	UBIAD1	F10	PROS1	
TRANSCRIPTION FACTORS REGULATE MIRNAS RELATED TO CARDIAC HYPERTROPHY%WIKIPATHWAYS_20260910%WP1559%HOMO SAPIENS	Transcription factors regulate miRNAs related to cardiac hypertrophy	RASGRF1	MYEF2	PPP3R1	TGFB1	STAT3	AKT2	NFKB1	AKT1	
HEMESYNTHESIS DEFECTS AND PORPHYRIAS%WIKIPATHWAYS_20260910%WP5169%HOMO SAPIENS	Hemesynthesis defects and porphyrias	UROS	PPOX	CPOX	HMBS	ALAD	ALAS2	ALAS1	FECH	UROD	
SELECTIVE EXPRESSION OF CHEMOKINE RECEPTORS DURING T CELL POLARIZATION%WIKIPATHWAYS_20260910%WP4494%HOMO SAPIENS	Selective expression of chemokine receptors during T cell polarization	CSF2	IL12B	CCR1	CCR3	CCR2	CXCR4	IL18R1	CCL3L1;CCL3L3;CCL3;CCL18	CCL4L2;CCL4L1;CCL4	IL12RB1	IL12RB2	IL2	CCR7	IFNGR1	IL4	CCR5	CCR4	IFNGR2	IFNG	CD40LG	IL12A	IL5	CD4	CXCR3	TGFB2	IL4R	TGFB1	CD28	TGFB3	
OMEGA 6 FATTY ACIDS IN SENESCENCE%WIKIPATHWAYS_20260910%WP5424%HOMO SAPIENS	Omega 6 fatty acids in senescence	HPGD	ALOX15	GSTP1	ALOX12	LTC4S	PTGS1	CYSLTR1	DPEP1	SERPINE1	ALOX5	LTA4H	PTGDS	CBR1-1	PTGR2	PTGIS	EPHX2	PLA2G4A	ALOX15B	MAPK11	SIRT1	RB1	ALOXE3	CDKN1A	GGT5	ABCC4	PRXL2B	ALOX5AP	GPX1	ALDH1A1	TBXAS1	PTGS2-2	AKR1B1	HPGDS	GGT1	FADS2	FADS1	PTGES2	DPEP2	TP53	ELOVL2	PTGES3-1	SLCO2A1	ELOVL5	DECR1	PTGES	
PHOSPHODIESTERASES IN NEURONAL FUNCTION%WIKIPATHWAYS_20260910%WP4222%HOMO SAPIENS	Phosphodiesterases in neuronal function	PDE6H	PDE10A	ADCY8	PRKG1	PDE5A	PDE6D	PDE6B	PDE6A	ADCY4	ADCY2	ADCY7	ADCY6	PDE3B	PDE4B	ADCY5	PDE4A	PDE4D-1	PPP1R1B	CREB1	ADCY10	ADCY9	GRIN2A	PDE1B	ADCY1	GRIN2C	GRIN2B	GRIN2D	ADCY3	GRIA1	PDE1A	CAMK2A	GUCY1B1	PDE7A	GUCY1A2	GUCY1A1	PDE8B	PDE8A	PDE2A	PDE4C	PDE1C	PDE3A	GRIN1	CHRNA7;CHRFAM7A	PDE7B	PRKACA-1	NOS1	DRD1	DRD2	ADORA2A	PDE12	PDE9A	PDE11A	PDE6C	
TNF ALPHA SIGNALING%WIKIPATHWAYS_20260910%WP231%HOMO SAPIENS	TNF alpha signaling	MAP3K7	PTPRCAP	NSMAF	MAPK9	NOXO1	MAPK3	NFKBIB	MAP2K4	CREBBP	PYGL	RFK	BAD	BTRC	IKBKB	IKBKG	CHUK	GRB2	CASP9	SKP1	TRAF2	SOS1	BCL2L1	NFKBIA	CASP3	PSMD2	CUL1	APAF1	BIRC2	BIRC3	KSR2	MADD	PLK1	DIABLO-1	CFLAR	TNF	CYBA	CSNK2A1;CSNK2A3	TANK	RFFL	CASP7	MAP3K8	BID	MAP3K3	TAB3	TAB2	TAB1	MAP3K14	NOX1	GLUL	NRAS	MAPK8	OTUD7B	CASP8	RIPK3	BAX	HRAS	PRKCZ	TRADD	TRAP1	HSP90AA1	RIPK1	FADD	SMPD2	MAP4K2	TNFRSF1A	MAP2K7	FBXW11	KRAS	TRAF1	MAP2K6	MAP2K3	JUN	MAP3K1	PPP2CB;PPP2CA	TNFAIP3	RAF1	NFKBIE	TNFRSF1B	CDC37	AKT1	MAP3K5	KSR1	REL	TBK1	NFKB1	TXN	MAPK1	NFKB2	RAC1	
MIRNA TARGETS IN ECM AND MEMBRANE RECEPTORS%WIKIPATHWAYS_20260910%WP2911%HOMO SAPIENS	miRNA targets in ECM and membrane receptors	COL3A1	COL1A2	LAMB2	LAMC1	COL4A2	ITGB6	COL4A1	ITGA1	THBS1	COL6A2	TNXB	SDC2	ITGA11	COL6A1	LAMA4	COL5A1	COL6A3	FN1	COL5A3	ITGB5	THBS2	COL5A2	
KISSPEPTIN KISSPEPTIN RECEPTOR SYSTEM IN THE OVARY%WIKIPATHWAYS_20260910%WP4871%HOMO SAPIENS	Kisspeptin kisspeptin receptor system in the ovary	PRKCA	PRKCQ	MAPK3	KISS1R	NRAS	CYP11A1	PRKCD	HRAS	PLCB3	PLCB4	ARRB1	ARRB2	AMH	PLCB1	PLCB2	KRAS	MMP9	RAF1	STAR	KISS1	HSD3B1;HSD3B2	BMP15-1	PDK1	PIK3CD	AKT2	PIK3CB	AKT1	PIK3CG	PRKCG	PIK3CA	PRKCH	MAP2K2;MAP2K1	NFKB1	MAPK1	PRKCB	GDF9	PRKCE	FSHR	
FIBRIN COMPLEMENT RECEPTOR 3 SIGNALING%WIKIPATHWAYS_20260910%WP4136%HOMO SAPIENS	Fibrin complement receptor 3 signaling	CXCL10	MYD88	ITGB2	TRAF6	CBLB	IRF3	PLAT	LY96	CD14	IL12B	IKBKB	FGB	IKBKG	FGA	CHUK	TICAM1	RHOA	LBP	FGG	IL6	RELA	PLG	SYK	SRC	NOS2	TICAM2	TIRAP	RASSF5	TYROBP	TLR4	TNF	TLR3	IFNB1-4	AKT1	FCER1G	CCL13;CCL2	IRAK1	IRAK2	REL	PIK3CA	CXCL2;CXCL3;CXCL1-1	IRAK4	ITGAM	NFKB1