OSTEOBLAST SIGNALING%WIKIPATHWAYS_20260810%WP227%RATTUS NORVEGICUS Osteoblast signaling Slc34a1 Col1a1 Bglap Pth Pdgfrb Pdgfra Tnfsf11 Fgf23 TNF ALPHA AND MUCUS PRODUCTION IN LUNG EPYTHELIUM%WIKIPATHWAYS_20260810%WP1487%RATTUS NORVEGICUS TNF alpha and mucus production in lung epythelium Mapk1 Tgfa Ikbkg Tnf Nfkbia Egfr Rela Il6 Map2k1 Tnfrsf1a Muc2 Ripk2 Tradd Rps6ka2 Nfkb1 Grb2 Traf2 Chuk Raf1 Sos1 Tlr4 Ikbkb Shc1 PENTOSE PHOSPHATE PATHWAY%WIKIPATHWAYS_20260810%WP282%RATTUS NORVEGICUS Pentose phosphate pathway Rpia Rpe G6pdx Taldo1 Pgls Kif1b Tkt Pgd ESTROGEN SIGNALING%WIKIPATHWAYS_20260810%WP1279%RATTUS NORVEGICUS Estrogen signaling Elk1 Mnat1 Hdac3 Hdac2 Hdac5 Taf13 Hdac1 Taf12 Akt1 Gtf2f2 Tbp Ccnh Prkaca Fos Gtf2b Gtf2e1 Shc2 Polr2c Src Polr2a Polr2b Taf9 Polr2g Polr2h Polr2f Polr2i Polr2j Gtf2h2 Gtf2h1 Gtf2h4 Gtf2h3 Gngt1 Jun Mapk14 Ccnd1 Ercc3 Gper1 Esr1 Crebbp Cdk7 Brca1 Gnb1 Taf7 Taf6 Taf5 Hras Ikbkb Mapk1 Map2k1 Nfkb1 Grb2 Chuk Sos1 Mapk9 Ilk Braf AMINO ACID CONJUGATION OF BENZOIC ACID%WIKIPATHWAYS_20260810%WP1287%RATTUS NORVEGICUS Amino acid conjugation of benzoic acid Glyat IL 6 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP135%RATTUS NORVEGICUS IL 6 signaling pathway Hdac1 Akt1 Fos Jun Mapk14 Crebbp Hras Socs3 Mapk8 Erbb2 Map3k7 Ppp2r3b Ppp2r3a Mapk3 Hsp90aa1 Map3k4 Ppp2r2c Ppp2r2b Foxo4 Rac1 Mapt Jak2 Foxo3 Jak1 Foxo1 Ppp2cb Ppp2ca Cd40 Plcg1 Gab1 Gab2 Cdk5r1 Eif4e Gsk3b Fgr Hck Ptpa Prkcd Btk Pik3r1 Sgk1 Pik3r2 Il6st Pxn Eif4ebp1 Nlk Ppp2r5c Cebpb Map2k6 Ppp2r5b Ppp2r5a Ncoa1 Rps6kb1 Hspb1 Ptpn11 Shc1 Tmem97 Mapk1 Fyn Il6r Inppl1 Lyn Rb1 Mapkapk2 Casp9 Il6 Bad Casp3 Map2k1 Ptk2b Ppp2r2a Bmx Ptk2 Rps6ka2 Map2k4 Nfkb1 Cdk9 Map2k2 Grb2 Stat5a Stat5b Raf1 Ppp2r1a Sos1 Ppp2r5e Tec Cdk5 Fes Stat3 Hnf1a Daxx CATECHOLAMINE SYNTHESIS%WIKIPATHWAYS_20260810%WP513%RATTUS NORVEGICUS Catecholamine synthesis Ddc Pnmt Th Pah Dbh STRIATED MUSCLE CONTRACTION%WIKIPATHWAYS_20260810%WP316%RATTUS NORVEGICUS Striated muscle contraction Acta1 Acta2 Tnnt2 Actc1 Tnnt1 Tpm4 Tpm3 Tpm2 Neb Tnni3 Tnni2 Tnni1 Tnnc2 Tnnc1 Tmod1 Myh3 Actn3 Mybpc3 Myl2 Actn4 Vim Myl9 Actg1 Tnnt3 HOMOLOGOUS RECOMBINATION%WIKIPATHWAYS_20260810%WP1296%RATTUS NORVEGICUS Homologous recombination Nbn Pold2 Rad51 Rad50 Pold1 Brca2 Rad52 Pold4 Pold3 Fsbp ACETATE MEDIATED PROMOTION OF METABOLIC SYNDROME%WIKIPATHWAYS_20260810%WP3650%RATTUS NORVEGICUS Acetate mediated promotion of metabolic syndrome Ins2 Gast NUCLEAR FACTOR ERYTHROID DERIVED 2 LIKE 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP2376%RATTUS NORVEGICUS Nuclear factor erythroid derived 2 like 2 signaling pathway Ran Jun Mapk14 Crebbp Brca1 Hras Mapk8 Map3k7 Mapk3 Gsk3b Prkcd Pik3r1 Pik3r2 Map2k6 Fyn Acta1 Acta2 Actc1 Actg1 Mapk7 Akr7a3 Akr7a2 Prkd3 Eif2ak3 Ube2k Hmox1 Gstk1 Herpud1 Sqstm1 Fth1 Tp53 Prdx1 Prkcq Actb Abcc3 Prkcg Abcc4 Abcc1 Map3k1 Scarb1 Prkci Nras Prkcb Prkce Gstt2 Prkca Gstt1 Vcp Txn Pmf1 Gstm5 Gstm6 Gstm3 Mafg Gstm4 Gstm1 Gstm2 Ubb Rras2 Slc1a4 Prkcz Gclm Mafk Pik3cd Actg2 Fosl1 Bach1 Pik3ca Pik3c2b Pik3c2a Dhcr7 Pik3c2g Ephx1 Akr1a1 Slc35b1 Dnajc5 Aldh3a1 Pik3c3 Ftl1 Xpo1 Mapk1 Gsto1 Gsto2 Slc2a1 Mgst2 Mgst1 Ugdh Cbr1 Nfe2l2 Rras Map2k1 Ldhb Gstp1 Pik3r5 Pik3r6 Pik3r3 Psmc6 Psmc5 Psmc2 Psmc4 Raf1 Psmc3 Map2k7 Aldoa Dnajb4 Nqo1 G6pdx Nqo2 Taldo1 Gss Fmo1 Sod3 Sod2 Sod1 Mapk9 Akr1b10 Usp14 Cdkn1a EBV LMP1 SIGNALING%WIKIPATHWAYS_20260810%WP1278%RATTUS NORVEGICUS EBV LMP1 signaling Mapk1 Traf6 Pdlim7 Ifnb1 Ccl5 Nfkb2 Rela Map3k14 Tradd Nfkb1 Mapk8 Chuk Map3k7 Ikbkb IL 3 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP319%RATTUS NORVEGICUS IL 3 signaling pathway Atf2 Spi1 Akt1 Ywhaq Birc5 Matk Crkl Prkaca Tnfrsf1b Bcl2l11 Csf2rb Kcnip3 Ywhab Rac2 Src Rara Rap1a Fcer2 Syk Mmp2 Bcl2l1 Rack1 Mmp9 Dnm1 Rxra Gsk3a Lck Crk Gata2 Vcl Mapk14 Chek1 Mapk7 Ptpn6 Il3ra Selp Il3 Pak1 Rps6kb2 Id1 Cdc42 Rapgef1 Bax Hras Socs3 Mapk8 Mapk3 Prkcb Rac1 Jak2 Prkca Jak1 Foxo1 Ppp2ca Gab1 Gab2 Gsk3b Hck Pik3r1 Pik3cd Pik3r2 Pxn Pik3ca Hspb1 Ptpn11 Shc1 Mapk1 Fyn Slc2a1 Lyn Mapkapk2 Bad Map2k1 Bmx Ptk2 Nfkb1 Grb2 Stat5a Stat5b Raf1 Sos1 Tec Fes Stat3 Mapk9 NUCLEOTIDE GPCRS%WIKIPATHWAYS_20260810%WP502%RATTUS NORVEGICUS Nucleotide GPCRs Lpar6 Adora1 P2ry2 P2ry1 Lpar4 Adora2b Adora2a P2ry6 TRANSLATION FACTORS%WIKIPATHWAYS_20260810%WP149%RATTUS NORVEGICUS Translation factors Eif4g3 Eif3b Eif3a Eif1a Eif5b Eif5a Eif2b3 Eif2b2 Eif2b5 Eif4e Eif2b4 Kcnq2 Eif2s2 Eef2k Eif2b1 Eif4h Eif1 Eif1ax Eif6 Eif4a2 Eif4a1 Eif4ebp1 Etf1 Gspt2 Cluh Eif2ak3 Eef1a2 Eef1d Eif3j Pycr3 Eif2s3 Eif2ak1 Eef1g Eif4ebp2 Eif2ak2 Eif3f Eif4g1 VEGFR 3 SIGNALING%WIKIPATHWAYS_20260810%WP1964%RATTUS NORVEGICUS VEGFR 3 signaling Mapk1 Plcg1 Casp9 Bad Akt1 Grb2 Mapk3 Nos3 Itpkc Flt4 Pik3cg Vegfd Vegfc Shc1 SEROTONIN AND ANXIETY%WIKIPATHWAYS_20260810%WP2132%RATTUS NORVEGICUS Serotonin and anxiety Arc Plek Htr2a Crh Htr2c Htr1a Grin2d Prkcb Ppp3ca Fos Nlgn1 Adra1a CFTR ACTIVITY IN THE PLASMA MEMBRANE%WIKIPATHWAYS_20260810%WP1488%RATTUS NORVEGICUS CFTR activity in the plasma membrane Ppp2ca Cftr Plcb3 Plcz1 Plcb2 Plcb1 Prkaca Nherf2 Nherf1 Prkaa2 Snap23 Pdzk1 Ezr Prkcg Rack1 MITOCHONDRIAL GENE EXPRESSION%WIKIPATHWAYS_20260810%WP1301%RATTUS NORVEGICUS Mitochondrial gene expression Tfb1m Tfb2m Camk4 Prkar1b Mterf1 Ppargc1a Nrf1 Ppargc1b Gabpa Myef2 Esrra Ppp3ca Gabpb2 Tfam Pprc1 MYOMETRIAL RELAXATION AND CONTRACTION PATHWAYS%WIKIPATHWAYS_20260810%WP140%RATTUS NORVEGICUS Myometrial relaxation and contraction pathways Atf2 Ywhaq Fos Ywhab Gngt1 Jun Gnb1 Plcg1 Prkcd Nos3 Crh Plcb3 Prkar1b Gabpa Prkd1 Acta1 Ets2 Rgs4 Rgs5 Actc1 Rgs2 Gja1 Rgs3 Rgs1 Crcp Rgs9 Rgs6 Rgs7 Plcg2 Myl4 Mylk2 Prkch Rxfp2 Rxfp1 Myl2 Atf5 Atf3 Maff Pkib Calca Actg1 Grk5 Grk4 Atf6b Gnaq Pkia Grk6 Pkig Oxtr Gucy1a1 Dgkz Gnb2 Gnb4 Gnb3 Rln1 Itpr3 Gng13 Itpr1 Ryr2 Atp2a3 Atp2a2 Oxt Adm Ywhah Ywhag Ywhae Prkcq Adcy3 Actb Adcy4 Nos1 Prkcg Adcy2 Guca2b Adcy7 Guca2a Crhr1 Adcy5 Lpar1 Prkcb Creb3 Prkce Adcy9 Cald1 Prkca Pde4b Prkacb Prkar1a Rgs20 Camk2g Rgs17 Camk2d Igfbp3 Gng3 Rgs19 Camk2b Gng2 Igfbp4 Vkorc1l1 Camk2a Prkcz Rgs14 Gng7 Igfbp1 Rgs16 Pde4d Arrb2 Gng8 Arrb1 Prkar2b Rgs10 Ackr5 Corin Ramp3 Il1b Gsto1 Il6 Nfkb1 WNT SIGNALING PATHWAY AND PLURIPOTENCY%WIKIPATHWAYS_20260810%WP1288%RATTUS NORVEGICUS Wnt signaling pathway and pluripotency Apc Plau Ppm1j Mapk10 Jun Ccnd1 Crebbp Tp53 Prkcq Map3k7 Ppp2r3a Ppp2r2c Prkci Ppp2r2b Prkcb Prkce Prkca Ppp2cb Ppp2ca Gsk3b Ptpa Prkcz Prkcd Fosl1 Nlk Ctnnb1 Pafah1b1 Rhoa Sox2 Ctbp1 Wnt5a Tmem97 Ctbp2 Wnt5b Wnt9b Ppard Axin1 Axin2 Fbxw2 Lef1 Wnt11 Tcf7 Lrp6 Ppp2r2a Nkd2 Lrp5 Wnt6 Wnt3a Dvl1 Dvl2 Dvl3 Wnt7a Ppp2r1a Wnt2 Tcf7l1 Wnt4 Cd44 Wnt3 Pou5f1 Fzd3 Ccnd2 Fzd2 Fzd4 Mapk9 Fzd9 Fzd8 Nanog MISMATCH REPAIR%WIKIPATHWAYS_20260810%WP1295%RATTUS NORVEGICUS Mismatch repair Lig1 Pcna Msh2 Rfc1 Pold1 GLYCOGEN METABOLISM%WIKIPATHWAYS_20260810%WP160%RATTUS NORVEGICUS Glycogen metabolism Ppp2cb Ppp2ca Gbe1 Calm3 Gsk3b Phkb Calm2 Gys1 Ptpa Gys2 Phka1 Ugp2 Phka2 Pgm1 Gyg1 Pygb Phkg1 Phkg2 Agl Ppp2r5b Ppp2r5a Gsk3a Ppp2r2a Ppp2r1a Ppp2r3a Ppp2r2c Ppp2r2b TNF ALPHA NF KB SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP457%RATTUS NORVEGICUS TNF alpha NF kB signaling pathway Traf6 Hdac2 Nfkb2 Hdac1 Map3k14 Akt1 Prkaca Tnfrsf1b Ywhab Src Nkiras1 Nr2c2 Nkiras2 Rack1 Tbkbp1 Map3k8 Rps11 Rpl6 Rps13 Pias3 Fbl Rpl30 Ube2i Akt2 Dpf2 Kcnq1 Polr1b Crebbp Rnf216 Polr1a Polr1g Fbxw11 Polr1e Casp8ap2 Txlna Tank Gtf2i Map3k3 Actl6a Map3k2 Smarce1 Tifa Ube2d2 Polr2sl1 Flna Btrc Nfkbiz Glg1 Bag4 Ripk3 G3bp2 Dcaf7 Cops3 Nfkbib Cav1 Ppp2ca Capn3 Kpna6 Ripk1 Mcc Gab1 Kpna3 Kpna2 Dap Cul1 Gsk3b Rel Tab2 Ccar2 Traf4 Mcm7 Pfdn2 Faf1 Csnk2a1 Tnfrsf8 Mark2 Psmd12 Smarcb1 Psmd13 Alpl Rasal2 Akap8 Psmb5 Csnk2b Rps6kb1 Rpl8l1 Hspb1 Cyld Fkbp5 Ptpn11 Mcm5 Fadd Tnip2 Tnip1 Pdcd2 Nsmaf Zfand5 Commd1 Trpc4ap Casp7 Casp3 Psmd6 Fancd2 Psmd3 Ptk2 Elp1 Casp2 Ktn1 Pebp1 Pkn1 Lrpprc Mtif2 Ywhah Ywhag Ywhae Map3k1 Prkcz Ikbkb Ikbkg Tnf Nfkbia Rela Tnfrsf1a Ripk2 Tradd Nfkb1 Traf2 Psmc2 Chuk Psmc3 INTERACTIONS BETWEEN CFTR AND OTHER ION CHANNELS%WIKIPATHWAYS_20260810%WP1485%RATTUS NORVEGICUS Interactions between CFTR and other ion channels Scnn1b Scnn1g Cftr Nherf1 FOCAL ADHESION%WIKIPATHWAYS_20260810%WP188%RATTUS NORVEGICUS Focal adhesion Elk1 Akt1 Rac2 Src Rap1a Crk Jun Vcl Mapk14 Ccnd1 Akt2 Pak1 Cdc42 Rapgef1 Hras Mapk8 Erbb2 Rac1 Cav1 Gsk3b Fgr Hck Pik3r1 Pik3r2 Pxn Map2k6 Pik3cg Vegfd Vegfc Fyn Bad Ptk2 Map2k2 Tnc Comp Mapk4 Ppp1r12a Tnn Akt3 Kdr Tnr Col1a2 Hgf Col5a1 Pgf Lama5 Reln Lama3 Lama4 Thbs1 Tln1 Thbs2 Thbs4 Blk Vasp Shc3 Srms Txk Mylk2 Pdgfc Chad Itga8 Itga6 Itga9 Vtn Itga3 Pdgfa Pdgfb Actg1 Itga10 Cav3 Cav2 Col4a1 Tesk2 Tnk2 Col4a2 Capn1 Ptk6 Col4a6 Igf1 Mylk Mapk7 Ibsp Igf1r Pelo Itgax Itgav Itgam Pdpk1 Itgae Itgal Rap1b Diaph1 Vwf Selenop Itgad Actb Itgb8 Itgb6 Itgb1 Itga2b Itgb5 Itgb2 Actn1 Itgb3 Met Col11a1 Col11a2 Dock1 Bcar1 Lamb3 Spp1 Pak6 Lamb1 Pak3 Pak2 Pak5 Pak4 Vegfb Mapk12 Egf Col6a2 Pten Map2k3 Styk1 Zyx Lamc1 Pik3cd Rock2 Rock1 Pip5k1c Pik3ca Col1a1 Pdgfrb Pdgfra Shc1 Mapk1 Egfr Map2k1 Pik3r5 Grb2 Raf1 Sos1 Ccnd2 Mapk9 Ilk Braf IRINOTECAN PATHWAY%WIKIPATHWAYS_20260810%WP124%RATTUS NORVEGICUS Irinotecan pathway Bche Abcc2 Ces1f Abcc1 Ces1e Ces1d Ces2c Abcg2 ID SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP397%RATTUS NORVEGICUS ID signaling pathway Elk1 Egf Atf3 Myog Ccna2 Ccne1 Myod1 Elk4 Id2 Lck Cd40lg Id4 Id3 Igf1 Hes1 Tcf7l2 Rb1 Psmd4 Igf1r Ngf Bmp6 Rela Pax2 Smad1 Id1 Rbl2 Bmp2 Rbl1 Smad4 Pax8 Nfkb1 Tert Smad5 Srebf1 Myf5 Kdr P53 SIGNAL PATHWAY%WIKIPATHWAYS_20260810%WP656%RATTUS NORVEGICUS p53 signal pathway Igf1 Igfbp3 Casp9 Casp3 Bax Tp53 Ccnb3 Gadd45g Gtse1 Bbc3 Siah1 Perp Pmaip1 Parp1 Mdm2 Ccne1 Cdk1 Fas Bid Rprm GPCRS CLASS C METABOTROPIC GLUTAMATE PHEROMONE%WIKIPATHWAYS_20260810%WP42%RATTUS NORVEGICUS GPCRs class C metabotropic glutamate pheromone Gprc5a Casr Gprc5d Grm1 Gprc5c Grm3 Grm2 Grm5 Grm4 Grm7 Gabbr1 Grm6 Gabbr2 Grm8 Gprc5b IL 1 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP355%RATTUS NORVEGICUS IL 1 signaling pathway Nfkbib Traf6 Plcg1 Map3k14 Akt1 Prkcz Il1rap Peli1 Irak4 Irak3 Irak2 Tollip Sirpa Il1a Il1r2 Capns1 Il1r1 Il1b Tab1 Il1rn Ptpn11 Capn1 Mapk1 Nfkbia Rela Map2k1 Sqstm1 Elp1 Nfkb1 Mapk8 Chuk Map3k7 Mapk3 CHOLESTEROL METABOLISM%WIKIPATHWAYS_20260810%WP632%RATTUS NORVEGICUS Cholesterol metabolism Soat1 Apoc2 Lpl Fdft1 Lss Hmgcs1 Hmgcr Apoe Mvd Msmo1 Srebf1 Dhcr7 Scarb1 Fdps Idi1 Mvk Rusc1 Apoc1 TRYPTOPHAN METABOLISM%WIKIPATHWAYS_20260810%WP270%RATTUS NORVEGICUS Tryptophan metabolism Gcdh Aoc1 Dhcr24 Haao Asmt Cyp2d26 Echs1 Cyp2e1 Kynu Cyp1a1 Cat Cyp2a2 Cyp2a1 Ube3a Acmsd Ido1 Hadh Tph1 Aldh1a1 Aldh3a2 Aldh2 Aldh9a1 Inmt Acad10 Cyp2j3 Hsd17b10 Cyp2b15 Wars1 Cyp2j4 Prmt1 Tdo2 Cyp4f1 Cyp2f2 Ddc Aadat Mdm2 Cyp1b1 Ogdh Cyp7b1 Aanat Afmid STEROID BIOSYNTHESIS%WIKIPATHWAYS_20260810%WP66%RATTUS NORVEGICUS Steroid biosynthesis Hsd3b6 Hsd17b7 Hsd3b5 Hsd17b3 Hsd3b1 Hsd17b4 Hsd17b1 Hsd17b2 F13b Cyp17a1 TRANSCRIPTIONAL ACTIVATION BY NFE2L2 IN RESPONSE TO PHYTOCHEMICALS%WIKIPATHWAYS_20260810%WP1280%RATTUS NORVEGICUS Transcriptional activation by Nfe2l2 in response to phytochemicals Mapk8 Nqo1 Cebpb Nfe2l2 Hmox1 Aimp2 Maf Prkca Gclm Ephb2 TYPE II INTERFERON SIGNALING IFNG %WIKIPATHWAYS_20260810%WP1289%RATTUS NORVEGICUS Type II interferon signaling IFNG Ifnb1 Spi1 Prkcd Il1b Cxcl10 Ptpn11 Cxcl9 Ifng Ifngr2 Oas1a Ifngr1 Reg1 Psmb9 Gbp1 Nos2 Hist1h4m Tap1 Ciita Irf4 Cybb Irf1 Irf2 Socs3 Irf8 Isg15 Irf9 Ifit2 Eif2ak2 Jak2 Jak1 PHASE I BIOTRANSFORMATIONS NON P450%WIKIPATHWAYS_20260810%WP1291%RATTUS NORVEGICUS Phase I biotransformations non P450 Pon3 Ces5a Pon1 Pon2 Ces2j Esd Lipa BRAIN DERIVED NEUROTROPHIC FACTOR%WIKIPATHWAYS_20260810%WP2148%RATTUS NORVEGICUS Brain derived neurotrophic factor Mapk1 Raf1 Map2k1 Ngfr Ntrk2 Bdnf Serpine1 Plat Plg STATIN PATHWAY%WIKIPATHWAYS_20260810%WP145%RATTUS NORVEGICUS Statin pathway Abca1 Soat1 Mttp Lpl Cyp7a1 Lcat Hmgcr Scarb1 Apoe Apoc1 KIT RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP147%RATTUS NORVEGICUS Kit receptor signaling pathway Stap1 Mitf Grb10 Socs5 Socs4 Akt1 Socs6 Ptpru Matk Cltc Crkl Sh3kbp1 Cblb Vav2 Csf2rb Dok1 Rps6ka1 Kit Tnfrsf10b Src Spred1 Mpdz Spred2 Grb7 Rasa1 Abl1 Grap Plce1 Sh2b2 Crk Ptpn6 Hras Prkcb Jak2 Prkca Plcg1 Fgr Hck Btk Pik3r1 Pik3r2 Pik3cg Ptpn11 Shc1 Mapk1 Fyn Lyn Bad Map2k1 Grb2 Stat5a Stat5b Raf1 Sos1 Tec Fes Stat3 NUCLEAR RECEPTORS IN LIPID METABOLISM AND TOXICITY%WIKIPATHWAYS_20260810%WP139%RATTUS NORVEGICUS Nuclear receptors in lipid metabolism and toxicity Abca1 Cyp7a1 Cyp2e1 Rara Abcc2 Nr1i3 Nr1i2 Abcb1a Abcd2 Cyp27b1 Abcd3 Cyp2c11 Abcb4 Ppard Cyp4b1 Rarb Cyp2b2 Cyp8b1 Vdr Nr1h3 Ppara Pparg Abcg1 Cyp24a1 Abcg5 Cyp26a1 Abcb11 Abcc3 VEGF RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260810%WP1965%RATTUS NORVEGICUS VEGF receptor signal transduction Mapk1 Pgf Plcg1 Mapkapk2 Casp9 Vegfb Bad Akt1 Pik3r3 Grb2 Sh2d2a Src Hspbp1 Raf1 Pxn Nos3 Prkci Rac1 Vegfc Prkca Shc1 FRUCTOSE METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260810%WP3894%RATTUS NORVEGICUS Fructose metabolism in proximal tubules Akr1b1 Fbp1 Slc2a5 Pfkp Gpi Slc5a9 Aldoa Tpi1 Psme3 Slc5a10 Sord Aldob G6pc1 Hk1 Khk Pfkl Tkfc Naglt1 HEPATOCYTE GROWTH FACTOR RECEPTOR SIGNALING%WIKIPATHWAYS_20260810%WP94%RATTUS NORVEGICUS Hepatocyte growth factor receptor signaling Elk1 Itga1 Gab1 Map4k1 Pten Crkl Fos Src Pxn Pik3ca Rap1a Rasa1 Ptpn11 Crk Mapk1 Jun Pak1 Map2k1 Ptk2b Rapgef1 Rap1b Ptk2 Hras Map2k2 Grb2 Mapk8 Raf1 Itgb1 Sos1 Mapk3 Stat3 Met Dock1 Hgf HEXOSES METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260810%WP3916%RATTUS NORVEGICUS Hexoses metabolism in proximal tubules Gpi Slc5a9 Tpi1 Psme3 Slc5a10 Sord Aldob G6pc1 Hk1 Khk Pfkl Tkfc Akr1b1 Fbp1 Slc2a5 Pfkp Pdhx Eno1 Eno3 Eno2 Pc Mpc1 Mpc2 Pdk4 Pgam2 Slc2a2 Pdk3 Pgam1 Pdk2 Pdk1 Pdhb Gapdh Ldha Dld Pklr Aldoc Acly Pdha1 Pgk1 Slc5a1 Pck1 Slc5a2 Got1 Mdh1 Mdh2 Got2 Pdp1 Pdp2 Ldhb Aldoa HYPOTHETICAL NETWORK FOR DRUG ADDICTION%WIKIPATHWAYS_20260810%WP1281%RATTUS NORVEGICUS Hypothetical network for drug addiction Acta1 Mapk1 Grm1 Grin2a Grin2d Nisch Grm5 Camk2b Krit1 Map2k1 Terf2ip Gria2 Gria1 Prkaca Ppa1 Drd1 Grin1 Adcy8 Grin2c Drd4 Grin2b Camk4 Mapk3 Prkce SPINAL CORD INJURY%WIKIPATHWAYS_20260810%WP2433%RATTUS NORVEGICUS Spinal cord injury Lilrb2 Sox9 Tnfsf13b Zfp36 Gap43 Gja1 Arg1 Prpg2 Omg Plxna2 Epha4 Mag Rtn4r Tacr1 Fos Anxa1 Pla2g2a Ccng1 Gadd45a Ntn1 Klk8 Il2 Rtn4 Vim Gfap Il1a Il4 Bcan Tnfsf13 Il1r1 C5 Mmp9 Tgfb1 Col4a1 Gdnf Ccl2 Pla2g5 Mbp Cd47 Cxcl1 Cxcl2 Pla2g6 Ccnd1 Fcgr2a Egr1 Selp Ptpra Ncan Acan Xylt1 Nox4 E2f1 E2f5 Tp53 Nos1 Mapk3 Prkca Rock2 Il1b Ppp3ca Cxcl10 Mapk1 Ifng Rb1 Il6 Nos2 Casp3 Grin1 Btg2 Chst11 Tlr4 Fkbp1a Ptprz1 Slit1 Slit2 Aqp4 Slit3 Ngfr Pdyn Cdk1 Bdnf Rgma Necab3 Vcan Sema6a INSULIN INDUCED PI3K AKT AND MAPK IN HEPATOCYTES%WIKIPATHWAYS_20260810%WP4229%RATTUS NORVEGICUS Insulin induced PI3K Akt and MAPK in hepatocytes Foxo1 Grb10 Akt1 Eif4e Gys1 Gys2 Rps6ka1 Eif4ebp1 Acly Rps6kb1 Pik3c3 Gsk3a Shc1 Mapk1 Bad Rptor Ins1 Irs2 Mtor Grb2 Pfkfb2 Rheb Foxk1 Raf1 Akt1s1 Sos1 Rps6 Mapk3 Tsc2 Tsc1 Mlst8 NOTCH SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP517%RATTUS NORVEGICUS Notch signaling pathway Maml1 Mfng Numb Hes5 Jag2 Jag1 Hdac1 Kat2a Rfng Numbl Notch1 Notch2 Lfng Notch3 Psen1 Psen2 Ctbp1 Ctbp2 Hes1 Crebbp Dvl1 Dvl2 Dvl3 Aph1a Ncstn Dtx2 Dtx3 Dtx4 Dll3 Dll4 Rbpjl COMPLEMENT AND COAGULATION CASCADES%WIKIPATHWAYS_20260810%WP547%RATTUS NORVEGICUS Complement and coagulation cascades Plau Vwf Cr2 Serping1 Cr1l Kng2l1 C3ar1 Serpinf2 Mbl1 Fgb Masp1 Masp2 Tfpi F13b F2 C8b F3 F7 F8 F9 Plaur Cfb C1qb Cfd C1qa Cd59b Cfh Cfi F2r Klkb1 Kng2 C2 Proc C4 C6 C9 Serpind1 Cd46 F10 C1s C1r F12 Thbd Pros1 Serpinc1 A2m Cpb2 Cd55 C1qc Serpine1 Plat Plg MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP358%RATTUS NORVEGICUS MAPK signaling pathway Elk1 Traf6 Mapk10 Nfkb2 Map3k14 Atf2 Akt1 Crkl Prkaca Fos Gadd45a Rap1a Il1a Il1r2 Il1r1 Tgfb1 Map3k8 Crk Jun Mapk14 Akt2 Pak1 Cdc42 Hras Mapk8 Map3k7 Map3k2 Mapk3 Map3k4 Flna Rac1 Mapt Tab2 Prkcd Nlk Map2k6 Hspb1 Ppp3ca Tmem97 Mapkapk2 Casp3 Map2k4 Daxx Akt3 Ntrk2 Bdnf Cacng8 Cacna1g Cacna1h Cacna1e Cacng7 Cacna1f Cacna1c Cacna1d Cacna1a Cacna1b Cacng1 Fgf2 Cacng4 Fgf1 Map3k6 Cacng5 Fgf4 Map3k5 Fgf3 Cacng3 Fgf6 Fgf5 Fgf8 Fgf7 Cacna1s Pdgfa Fgf9 Map3k20 Rasa1 Lamtor3 Rasgrp3 Rasgrp4 Rasgrp1 Flnc Rasgrp2 Flnb Cdc25b Jund Stmn1 Stk4 Map4k3 Tgfb2 Tgfb3 Nf1 Ppp3cc Ppp3cb Fgfr3 Fgfr4 Fgfr1 Fgfr2 Map4k2 Tp53 Rasgrf2 Cd14 Faslg Fgf16 Fgf17 Prkcg Fgf14 Ppp5c Pla2g4b Map3k1 Fgf18 Pla2g4e Fgf19 Nras Pla2g4d Pla2g4a Fgf12 Fgf13 Prkca Fgf10 Fgf11 Prkacb Nfatc1 Nfatc3 Fgf20 Rps6ka3 Rps6ka4 Pak2 Cacna2d1 Map4k1 Sos2 Cacna2d3 Cacna2d4 Gna12 Egf Dusp16 Rras2 Ppm1b Ptpn7 Ptpn5 Dusp3 Ntf4 Dusp2 Hspa1l Dusp4 Arrb2 Ntf3 Arrb1 Dusp10 Dusp9 Dusp8 Mapk13 Cacnb4 Cacnb1 Cacnb2 Il1b Pdgfrb Taok2 Taok1 Taok3 Elk4 Mapkapk5 Ikbkb Mos Ntrk1 Mapk1 Mef2c Rapgef2 Ikbkg Mapk8ip1 Mapk8ip3 Mknk1 Egfr Ngf Map3k11 Rela Tgfbr1 Rras Map2k1 Tnfrsf1a Nfkb1 Grb2 Traf2 Chuk Raf1 Sos1 Map2k7 Fas Mapk9 Braf SULINDAC METABOLIC PATHWAY%WIKIPATHWAYS_20260810%WP2541%RATTUS NORVEGICUS Sulindac metabolic pathway Msra Msrb2 Cyp1a1 REGULATION OF ACTIN CYTOSKELETON%WIKIPATHWAYS_20260810%WP351%RATTUS NORVEGICUS Regulation of actin cytoskeleton Rassf7 Apc Gna13 Fgd1 Csk Tmsb4x Arhgap35 Wasf2 Gsn Wasf1 Limk1 Pip5k1b Pip5k1a Crk Vcl Pak1 Cdc42 Ins1 Mapk3 Rac1 Pik3r1 Pik3r2 Pxn Pik3cg F2 F2r Ptk2 Ezr Mapk4 Fgf2 Fgf1 Fgf4 Fgf3 Fgf6 Fgf5 Fgf8 Fgf7 Pdgfa Fgf9 Actg1 Ins2 Mylk Fgfr3 Fgfr4 Fgfr1 Fgfr2 Cd14 Actb Fgf16 Fgf17 Fgf14 Fgf18 Fgf19 Nras Fgf12 Fgf13 Dock1 Fgf10 Bcar1 Fgf11 Pak6 Fgf20 Pak3 Pak2 Itga1 Pak5 Sos2 Pak4 Gna12 Egf Rras2 Pik3cd Rock1 Pik3ca Pik3c2b Pik3c2a Pik3c2g Pdgfrb Pdgfra Rhoa Pik3c3 Fgf23 Mos Mapk1 Egfr Rras Map2k1 Cfl1 Cfl2 Pip4k2b Pik3r5 Pfn1 Pip4k2a Pik3r3 Arhgef7 Arhgef6 Arhgef1 Myh10 Raf1 Chrm1 Chrm3 Sos1 Nckap1 Chrm2 Chrm5 Chrm4 Slc9a1 Ssh3 Ssh2 Ssh1 Arpc5 Enah Baiap2 Braf Git1 OXIDATIVE STRESS RESPONSE%WIKIPATHWAYS_20260810%WP173%RATTUS NORVEGICUS Oxidative stress response Mapk14 Mapk10 Mgst1 Hmox1 Cyp1a1 Cat Nfix Gpx3 Fos Txn2 Nfkb1 Txnrd2 Cyba Junb Xdh Nqo1 Sod3 Sod2 Sod1 Gstt2 BETA OXIDATION OF UNSATURATED FATTY ACIDS%WIKIPATHWAYS_20260810%WP418%RATTUS NORVEGICUS Beta oxidation of unsaturated fatty acids Hadha Hadhb Eci1 Acadm Decr1 RETINOL METABOLISM%WIKIPATHWAYS_20260810%WP1297%RATTUS NORVEGICUS Retinol metabolism Cyp2e1 Rara Dhrs3 Sult2b1 Cd36l1 Rdh12 Aldh1a3 Rxra Rdh10 Adh5 Adh4 Cyp26b1 Adh1 Lpl Bco1 Sult1a1 Npc1l1 Rarb Rpe65 Rxrb Rbp7 Abcg8 Rbp4 Retsat Aldh1a1 Crabp2 Cd36 Rxrg Abcg5 Lrat Cyp26a1 Rlbp1 Scarb1 NON HOMOLOGOUS END JOINING%WIKIPATHWAYS_20260810%WP1277%RATTUS NORVEGICUS Non homologous end joining Xrcc6 Prkdc Xrcc4 Rad50 ACE INHIBITOR PATHWAY%WIKIPATHWAYS_20260810%WP557%RATTUS NORVEGICUS ACE inhibitor pathway Kng2l1 Ren1 Ace Agtr1b Agtr2 Nos3 Bdkrb2 Agt Kng2 P38 MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP294%RATTUS NORVEGICUS p38 Mapk signaling pathway Elk1 Ripk1 Atf2 Map3k5 Map2k6 Hspb1 Mapkapk5 Shc1 Mapk14 Tgfb2 Mknk1 Mapkapk2 Tgfbr1 Cdc42 Tradd Map2k4 Hras Grb2 Traf2 Map3k7 Map3k1 Max Daxx Pla2g4a Map3k9 Mef2d Rac1 Rps6ka5 FATTY ACID OMEGA OXIDATION%WIKIPATHWAYS_20260810%WP133%RATTUS NORVEGICUS Fatty acid omega oxidation Adh6 Acad10 Adh1 Cyp2e1 Cyp1a1 Aldh1a1 Aldh2 Cyp4a2 Cyp3a2 Adh5 Adh4 Adh7 NUCLEOTIDE METABOLISM%WIKIPATHWAYS_20260810%WP146%RATTUS NORVEGICUS Nucleotide metabolism Dhfr Prps2 Polb Impdh1 Nme2 Mthfd2 Hprt1 Polg Adss2 Pold1 Sat1 Srm PROTEASOME DEGRADATION%WIKIPATHWAYS_20260810%WP302%RATTUS NORVEGICUS Proteasome degradation Psma5 Rpn2 Psma2 Rpn1 Psme2 Psme1 Psmd11 Ube2b Psmd12 Uchl3 Psmb8 Psmd13 Psmb6l1 Psmb7 Psmd8 Uchl1 Psmb5 Psmb1 Psmd2 Psmd5 Psmb2 Ube2d3 Ube2d1 Psmd4 Psmb9 Psmd6 Psmd3 Psmc6 Psmc5 Psmc2 Psmc4 Psmc3 METHYLATION%WIKIPATHWAYS_20260810%WP1282%RATTUS NORVEGICUS Methylation Comt Mat2a Mat1a Hnmt Pnmt Inmt MONOAMINE GPCRS%WIKIPATHWAYS_20260810%WP276%RATTUS NORVEGICUS Monoamine GPCRs Adra1a Htr2a Adra2a Htr2c Adra2c Htr1a Adra2b Htr4 Hrh1 Htr6 Htr7 Hrh2 Adrb1 Drd1 Drd3 Drd5 Adra1b Adrb3 Drd4 Adra1d Chrm1 Htr1d Chrm3 Htr1f Htr5b Chrm2 Htr5a Chrm5 Chrm4 OXIDATIVE PHOSPHORYLATION%WIKIPATHWAYS_20260810%WP1283%RATTUS NORVEGICUS Oxidative phosphorylation Atp5pf Ndufb10 Atp5po Ndufs2 Ndufs5 Ndufs4 Ndufs6 Mt-co3 Ndufs8 Mt-nd5 Adck2 Mt-nd4 Ndufb2 Mt-atp6 Mt-nd6 Atp5mc1 Mt-nd1 Mt-nd3 Mt-nd4l Mt-nd2 Ndufb8 Ndufb7 Atp5mc3 Atp5mf Atp5me Ndufv1 Ndufv3 Atp5f1a Ndufa10l1 Ndufab1 Ndufc1 Coxfa4 Ndufc2 Ndufa5 Gzmb Atp5pb Gzmc Ndufa9 Ndufa8 GLUCOCORTICOID METABOLISM%WIKIPATHWAYS_20260810%WP305%RATTUS NORVEGICUS Glucocorticoid metabolism Hsd11b1 Hsd11b2 Cyp17a1 Cyp21a1 Cyp11a1 Akr1c9 EPO RECEPTOR SIGNALING%WIKIPATHWAYS_20260810%WP1284%RATTUS NORVEGICUS EPO receptor signaling Mapk1 Ptprc Epo Map2k1 Akt1 Ptpru Irs2 Map2k2 Grb2 Stat5a Stat5b Src Raf1 Sos1 Pdk1 Mapk3 Rasa1 Stat3 Pik3cg Jak2 Shc1 ESTROGEN METABOLISM%WIKIPATHWAYS_20260810%WP1302%RATTUS NORVEGICUS Estrogen metabolism Comt Sult1a1 Sult1e1 Arsl Nqo1 Gstm1 Cyp1a1 Cyp1b1 ADIPOGENESIS%WIKIPATHWAYS_20260810%WP155%RATTUS NORVEGICUS Adipogenesis Gadd45a Rara Tgfb1 Rxra Cyp26b1 Gata2 Lpl E2f1 Rxrg Irs2 Socs3 Agt Mef2d Foxo1 Il6st Cebpb Ncoa1 Cfd Rb1 Stat5a Stat5b Ppargc1a Stat3 Hnf1a Serpine1 Ins2 Igf1 Nampt Nrip1 Trib3 Ahr Nr1h3 Lifr Ppara Prlr Pparg Bscl2 Foxc2 Twist1 Ebf1 Cyp26a1 Mif Retn Mbnl1 Frzb Cntfr Gata3 Gata4 Nr3c1 Gh1 Hif1a Gtf3a Ndn Cisd1 Pck2 Egr2 Lif Bmp4 Bmp3 Wwtr1 Bmp1 Lipe Hmga1 Plin2 Adipoq Epas1 Slc2a4 Scd1 Sfrp4 Nr2f1 Ptgis Klf15 Ncor1 Ucp1 Gadd45b Pnpla3 Cebpd Ncoa2 Zmpste24 Asip Osm Lpin3 Celf1 Lpin1 Dlk1 Mixl1 Mef2a Pck1 Mef2b Klf5 Mef2c Lep Wnt5b Id3 Spock1 Gdf10 Tnf Ppard Agpat2 Il6 Rbl2 Bmp2 Rbl1 Dvl1 Srebf1 Fas Necab3 Cdkn1a NOD LIKE RECEPTOR NLR SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP1294%RATTUS NORVEGICUS Nod like receptor NLR signaling pathway Mapk8 Chuk Ikbkg Map3k7 Cd40 Rela Ephb2 Ikbkb SYNTHESIS AND DEGRADATION OF KETONE BODIES%WIKIPATHWAYS_20260810%WP349%RATTUS NORVEGICUS Synthesis and degradation of ketone bodies Hmgcl Bdh1 Oxct1 Hmgcs2 INSULIN SIGNALING%WIKIPATHWAYS_20260810%WP439%RATTUS NORVEGICUS Insulin signaling Elk1 Rrad Inpp4a Ppp1r3a Vamp2 Mapk10 Rps6ka6 Mink1 Sgk3 Map3k14 Sgk2 Akt1 Myo1c Enpp1 Ptpn1 Stx4 Gys1 Arhgap33 Gys2 Fos Map3k10 Mapk11 Shc2 Gyg1 Rac2 Map3k8 Gsk3a Crk Jun Mapk14 Akt2 Egr1 Rps6kb2 Rapgef1 Rptor Hras Irs2 Mtor Mapk8 Map3k3 Rheb Map3k7 Map3k2 Mapk3 Tsc2 Tsc1 Map3k4 Map3k9 Rac1 Rps6ka5 Foxo3 Foxo1 Gab1 Eif4e Gsk3b Prkcd Pik3r1 Sgk1 Pik3r2 Eif4ebp1 Map2k6 Pik3cg Rps6kb1 Ptpn11 Inppl1 Reg1 Map2k4 Prkaa2 Snap23 Map2k2 Mapk4 Grb10 Map3k6 Shc3 Cblb Map3k5 Prkch Rps6ka1 Sh2b2 Map4k3 Igf1r Trib3 Pdpk1 Map4k2 Prkcq Map3k1 Prkci Prkcb Prkca Pfkl Rps6ka3 Rps6ka4 Lipe Map4k1 Sos2 Mapk12 Slc2a4 Pten Prkcz Pik3cd Pik3c2a Mapk13 Pik3c2g Pik3c3 Ikbkb Shc1 Mapk1 Slc2a1 Map3k11 Cyth3 Map2k1 Grb14 Stxbp1 Stxbp2 Stxbp3 Stxbp4 Rps6ka2 Prkaa1 Kif5b Grb2 Cblc Insr Raf1 Flot2 Flot1 Sos1 Map2k7 Map4k5 Rab4a Xbp1 Kif3a Tbc1d4 Ehd1 Ehd2 Snap25 Arf1 Mapk9 Rhoj Ptprf Cap1 GLUTATHIONE METABOLISM%WIKIPATHWAYS_20260810%WP469%RATTUS NORVEGICUS Glutathione metabolism Gstm6 Gstm3 Gstm2 Gpx3 Gclm Ggt5 Anpep Ggt1 Oplah G6pdx Gss Gstt2 Gstt1 APOPTOSIS%WIKIPATHWAYS_20260810%WP1290%RATTUS NORVEGICUS Apoptosis Mapk10 Akt1 Birc5 Tnfrsf1b Bcl2l11 Tnfrsf10b Prf1 Hells Traf1 Bcl2l2 Xiap Bnip3l Irf3 Lta Irf7 Irf5 Irf6 Diablol1 Bak1 Tp73 Jun Tnfrsf25 Igf2 Dffa Igf1r Dffb Tp63 Bax Tp53 Faslg Map3k1 Nfkbib Ripk1 Pik3r1 Ikbkb Fadd Ikbkg Nfkbia Rela Casp9 Bad Casp7 Casp3 Tnfrsf1a Irf4 Tradd Irf1 Casp2 Map2k4 Nfkb1 Irf2 Traf2 Chuk Pmaip1 Fas Bid GLUCOCORTICOID EFFECT ON TARGET GENE EXPRESSION%WIKIPATHWAYS_20260810%WP1963%RATTUS NORVEGICUS Glucocorticoid effect on target gene expression Nfkbia Tsc22d3 Nr3c1 Hspa4 Rras Mt-co2 Fkbp4 Pla2g4a Anxa1 Nfkb1 S1P RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260810%WP1312%RATTUS NORVEGICUS S1P receptor signal transduction Mapk1 Akt2 Mapk12 Plcb3 Akt1 Smpd2 Plcb2 Plcb1 Asah1 Sphk2 Sphk1 S1pr1 Gnai1 S1pr3 Gnai3 Pik3c2b Mapk3 Mapk4 Akt3 INTEGRIN MEDIATED CELL ADHESION%WIKIPATHWAYS_20260810%WP74%RATTUS NORVEGICUS Integrin mediated cell adhesion Mapk10 Tln1 Akt1 Vasp Shc3 Vav2 Mylk2 Itga8 Itga6 Rac2 Src Itga9 Rap1a Itga3 Itga10 Capns1 Cav3 Cav2 Capn1 Crk Vcl Mapk7 Akt2 Itgax Itgav Pak1 Itgam Pdpk1 Itgae Cdc42 Itgal Rapgef1 Rap1b Hras Selenop Itgad Itgb8 Vav3 Itgb6 Itgb1 Itgb4 Itga2b Itga2 Itgb5 Rho Itgb2 Capn9 Git2 Itgb3 Capn5 Capn7 Capn6 Rac1 Capn2 Dock1 Bcar1 Pak6 Cav1 Pak3 Capn3 Pak2 Itga1 Pak4 Mapk12 Map2k3 Zyx Rock2 Rock1 Pik3r2 Pxn Map2k6 Shc1 Mapk1 Fyn Map2k1 Ptk2 Arhgef7 Map2k2 Grb2 Raf1 Sos1 Mapk4 Akt3 Ilk Braf GPCRS OTHER%WIKIPATHWAYS_20260810%WP409%RATTUS NORVEGICUS GPCRs other Grm1 Grm8 Rxfp1 Adora2a S1pr1 Prokr2 Adgrg1 Cxcr1 Ednra Gnrhr Ntsr1 Fshr Gpr61 Or1n1 Ccr5 Ccr2 Gpr176 Cckbr Alg6 Adgrl2 Adgrl3 Gpr135 Sstr2 Smo Taar3 Rxfp3 Taar2 Taar5 Ghrhr Gpr183 C5ar2 Or3a1e Or2a5 Ptgfr Hrh4 Gpr88 Or2f1 Celsr2 Cnr1 Gpr18 Grpr Uts2r P2ry13 Htr2a Gpr17 Ltb4r2 Lgr6 Or10a2 F2r Htr7 Drd3 Adra1d Drd4 Htr1f Chrm3 Chrm2 AFLATOXIN B1 METABOLISM%WIKIPATHWAYS_20260810%WP1300%RATTUS NORVEGICUS Aflatoxin B1 metabolism Akr7a3 Akr7a2 Gstm1 Ephx1 TOLL LIKE RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP1309%RATTUS NORVEGICUS Toll like receptor signaling pathway Traf6 Ifnb1 Mapk10 Ccl5 Nfkb2 Akt1 Fos Tollip Irf3 Map3k8 Irf7 Irf5 Jun Mapk14 Akt2 Cd14 Mapk8 Map3k7 Mapk3 Rac1 Spp1 Cd40 Ripk1 Map2k3 Tab2 Pik3r1 Pik3cd Pik3r2 Pik3ca Mapk13 Map2k6 Il1b Pik3cg Ikbkb Cxcl10 Cxcl9 Mapk1 Fadd Ikbkg Tnf Nfkbia Il12b Rela Il12a Il6 Ticam2 Map2k1 Lbp Cd86 Cd80 Pik3r5 Ly96 Tlr1 Pik3r3 Map2k4 Nfkb1 Ifna4 Ifna1 Tlr8 Tlr7 Chuk Tlr6 Tlr5 Map2k7 Tlr4 Tlr3 Tlr2 Cxcl11 Ifnar1 Ccl4 Ccl3 Akt3 Mapk9 RENIN ANGIOTENSIN SYSTEM%WIKIPATHWAYS_20260810%WP376%RATTUS NORVEGICUS Renin angiotensin system Elk1 Enpep Ctsa Nln Cma1 Mapk10 Lnpep Mas1 Itpr2 Atf2 Prkaca Fos Anpep Jun Itpr3 Pak1 Itpr1 Mapk8 Prkcq Ren1 Ace Mapk3 Agtr2 Map3k1 Agt Rac1 Jak2 Pak6 Pak3 Pak2 Pak5 Pak4 Pik3ca Mapk13 Ikbkb Shc1 Mapk1 Ikbkg Rela Ptk2b Plcb1 Ptk2 Map2k4 Grb2 Raf1 Map2k7 Stat3 Ctsg Cpa3 Mme Mapk9 Agtr1 Ace2 Ptgir SELENIUM METABOLISM SELENOPROTEINS%WIKIPATHWAYS_20260810%WP1293%RATTUS NORVEGICUS Selenium metabolism selenoproteins Selenbp1 Msrb1 Eefsec Crem Sp3 Selenof Sars2 Gpx3 Fos Selenoi Txnrd2 Sars1 Selenok Fabp1 Selenoo Gpx6 Selenos Dio1 Selenot Dio2 Dio3 Selenov Selenow Sephs1 Trnau1ap Jun Rpl30 Rela Nfe2l2 Nfkb1 Selenop APOPTOSIS MODULATION BY HSP70%WIKIPATHWAYS_20260810%WP487%RATTUS NORVEGICUS Apoptosis modulation by HSP70 Hspa1b Fadd Mapk10 Ripk1 Casp9 Casp7 Casp3 Tnfrsf1a Casp2 Nfkb1 Faslg Map3k1 Fas Cycs Bid Casp6 Aifm1 INFLAMMATORY RESPONSE PATHWAY%WIKIPATHWAYS_20260810%WP40%RATTUS NORVEGICUS Inflammatory response pathway Ifng Il4r Lama5 Lamb1 Cxhxorf65 Cd40 Il2ra Il2rb Il2rg Thbs1 Il5 Il5ra Tnfrsf1a Cd86 Cd80 Tnfrsf1b Lamc1 Il2 Vtn Il4 Col1a1 Col1a2 Lck Cd40lg POLYOL PATHWAY%WIKIPATHWAYS_20260810%WP1303%RATTUS NORVEGICUS Polyol pathway Akr1b1 Sord Aldob Khk IL 5 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP44%RATTUS NORVEGICUS IL 5 signaling pathway Elk1 Atf2 Akt1 Crkl Rps6ka1 Shc2 Syk Sh2b2 Gsk3a Jun Mapk14 Ptpn6 Il5 Il5ra Rap1gap Itgam Alox5 Pim1 Sox4 Rapgef1 Sdcbp Bax Alox5ap Hras Hcls1 Unc119 Cdkn1b Mapk3 Itgb2 Pla2g4a Prkcb Rac1 Jak2 Foxo3 Jak1 Gsk3b Hck Prkcd Btk Pik3r1 Pik3r2 Ctnnb1 Pik3cg Ptpn11 Shc1 Mapk1 Lyn Nfkbia Ptk2b Nfkb1 Grb2 Stat5a Stat5b Raf1 Stat3 Mapk9 FATTY ACID BIOSYNTHESIS%WIKIPATHWAYS_20260810%WP504%RATTUS NORVEGICUS Fatty acid biosynthesis Echs1 Pc Scd1 Hadh Mecr Echdc3 Echdc1 Echdc2 Acaa2 Acsl1 Decr1 Fasn Acsl5 Acsl6 Acly Acsl3 Acacb Acaca MIR219 IN OLIGODENDROCYTE DIFFERENTIATION AND MYELINATION%WIKIPATHWAYS_20260810%WP2811%RATTUS NORVEGICUS mir219 in oligodendrocyte differentiation and myelination Neurod1 Sox6 Hes5 Pdgfra Zbtb18 Foxj3 Elovl7 IL 9 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP8%RATTUS NORVEGICUS IL 9 signaling pathway Mapk1 Cxhxorf65 Kat5 Il9 Jak3 Il2rg Il9r Map2k1 Akt1 Irs2 Socs3 Grb2 Pik3r1 Stat5a Stat5b Mapk3 Stat3 Ptpn11 Vcp Shc1 Jak1 GPCRS CLASS A RHODOPSIN LIKE%WIKIPATHWAYS_20260810%WP473%RATTUS NORVEGICUS GPCRs class A rhodopsin like Or6b1 Gpr15 Or2c1 Or13c7d Gpr12 Adora3 Or2t1 Cckar Opn1sw Npbwr1 Nmur2 Prlhr Npy5r Ntsr2 Brs3 Gpr25 Ptger4 Mc2r Gpr27 Ptger2 Gpr22 Ptger3 Gpr21 Ptger1 Ccr9 Mchr1 Ccr7 Ccr6 Ccr3 Mtnr1a Npy4r Gpr37 Gpr39 Or11a4 Rgr Or14j1 Gper1 Mc4r Or10j27 Ptafr Npffr1 Or2f2 Npffr2 Ptgdr2 Hcrtr1 Or5ap2b Adora2b Or2w1 Adora2a Gpr37l1 P2ry6 Cysltr2 Lpar6 Cysltr1 Adora1 Npy2r P2ry2 Ackr4 P2ry1 Gpr4 Lpar4 Cnr2 Rho Gpr3 Agtr2 Ackr2 Bdkrb2 Gpr6 P2ry10 Mc3r Or2ag1 P2ry12 P2ry14 F2rl1 Cxcr1 Or10a4 Ednra Gpr50 Oprk1 Ntsr1 F2rl2 Fshr F2rl3 Ccr5 Ccr2 Cckbr Sstr2 C3ar1 C5ar2 Or3a1e Ptgfr Or2f1 Cnr1 Gpr18 Adra1a Grpr P2ry13 Gpr17 Htr2a Adra2a Htr2c Adra2c Htr1a Adra2b Htr4 F2r Hrh1 Htr6 Htr7 Hrh2 Adrb1 Drd3 Drd5 Adra1b Adrb3 Adra1d Htr1d Htr1f Htr5a Agtr1 Ptgir Mas1 Oxtr Hcar1 Ghsr Ednrb Gpr161 Npy1r Rrh Ptgdr Or3a1 Oprd1 Or2h2 Gpr65 Or2h1 Gpr68 Cxcr4 Gpr63 Oprl1 Gpr173 Gpr174 Galr2 Gpr171 Galr3 Galr1 Cmklr1 Lhcgr Sstr5 Sstr4 Sstr3 Olr226 Sstr1 Avpr1b Mc5r Oprm1 Gpr75 Tbxa2r Or7c70 Ffar3 Fpr1 Aplnr Nmbr Fpr3 Drd1 Ffar1 Bdkrb1 Fpr2 Ffar2 Drd4 Ccr10 Chrm1 Or2b2 Chrm3 Or2j3 Chrm2 Hrh3 Chrm5 Or5v1b Chrm4 Gpr85 Or7a36 Opn4 Xcr1 Lpar5 Opn3 Olr1073 Gpr19 Sucnr1 ONE CARBON METABOLISM%WIKIPATHWAYS_20260810%WP1292%RATTUS NORVEGICUS One carbon metabolism Dhfr Mat1a Mthfd1l Ahcy Folh1 Mtrr Mthfd2 Mtr Ftcd Ahcyl2 Bhmt Tcn2 Dnmt3a Aldh1l1 Shmt1 Gart Mthfr METAPATHWAY BIOTRANSFORMATION%WIKIPATHWAYS_20260810%WP1286%RATTUS NORVEGICUS Metapathway biotransformation Fmo4 Hs6st1 Cyp7a1 Naa50 Cyp26c1 Cyp46a1 Nat8 Nat1 Nat2 Ephx2 Gal3st4 Gal3st3 Nat9 Sult2b1 Cyp21a1 Cyp26b1 Cyp27b1 Sult1a1 Akr7a3 Sult1e1 Akr7a2 Cyp8b1 Gstk1 Cyp24a1 Glyat Inmt Cyp26a1 Cyp2f2 Cyp1b1 Cyp7b1 Akr1b1 Gstm5 Gstm4 Gstm1 Cyp2e1 Cyp1a1 Chst10 Chst12 Cyp2u1 Chst13 Cyp4f18 Chst14 Cyp4f17 Sult6b2 Ephx1 Naa40 Akr1a1 Ugt2b1 Cyp17a1 Nat10 Ndst1 Cyp4x1 Ndst3 Hs3st3a1 Comt Gsto1 Sult4a1 Chst1 Sult2a1 Chst3 Hnmt Mgst1 Sult2a6 Chst4 Chst6 Chst9 Akr1c1 Zfp628 Gstp1 Gstz1 Hs3st2 Sult1b1 Hs3st5 Hs3st6 Cyp2s1 Hs3st3b1 Gstm7 Cyp4f39 Baat Chst11 Naa20 Akr1d1 Gstcd Kcnab2 Cyp51a1 Gss Kcnab3 Fmo1 Hs2st1 Tpmt Fmo3 Fmo2 Akr1b10 Fmo5 Hs6st3 ANGIOTENSIN II SIGNALING ACUTE IN THICK ASCENDING LIMBS%WIKIPATHWAYS_20260810%WP3887%RATTUS NORVEGICUS Angiotensin II signaling acute in thick ascending limbs Plcg1 Mas1 Itpr2 Akt1 Calm3 Pten Calm2 Pde2a Prkaca Plcg2 Agtrap Arrb2 Nos3 Gnaq Dnm1 Akt2 Itpr3 Itpr1 Pdpk1 Nox4 Prkcg Agtr1b Agtr2 Akt3 Agtr1 Prkca TCA CYCLE%WIKIPATHWAYS_20260810%WP347%RATTUS NORVEGICUS TCA cycle Mdh1 Mdh2 Pc Pdk4 Fh Sdhc Sdhb Pdk3 Sdha Idh3b Pdk2 Afdn Pdhb Suclg1 Suclg2 Dld Pdha1 Ogdh GLUCURONIDATION%WIKIPATHWAYS_20260810%WP1276%RATTUS NORVEGICUS Glucuronidation Pgm1 Ugdh Ugt2b7 Pgm2 Pgm5 Ugt2b35 Ugt2b1 Ugt2b34 Ugt2a1 Hk1 Ugp2 WNT MYOFIBROBLASTIC ACTIVATION OF HEPATIC STELLATE CELLS%WIKIPATHWAYS_20260810%WP3649%RATTUS NORVEGICUS Wnt myofibroblastic activation of hepatic stellate cells Pparg Wnt3a ERBB SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP1299%RATTUS NORVEGICUS ErbB signaling pathway Elk1 Plcg1 Pak4 Gab1 Egf Gsk3b Camk2a Shc2 Src Eif4ebp1 Abl1 Ereg Rps6kb1 Hbegf Nrg2 Nrg1 Crk Mapk1 Jun Areg Tgfa Btc Nrg4 Nrg3 Egfr Bad Map2k1 Pik3r5 Ptk2 Hras Mtor Grb2 Mapk8 Cblc Stat5a Cdkn1b Erbb2 Map2k7 Sos1 Akt3 Prkca Cdkn1a WNT SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP375%RATTUS NORVEGICUS Wnt signaling pathway Apc Sox9 Akt1 Tbp Jun Ccnd1 Cdh1 Tax1bp3 Skp1 Sfrp2 Sfrp1 Dkk1 Magi3 Ror2 Crybb2 Csnk1d Sall1 Cdc25c Mapk8 Senp2 Ruvbl1 Map3k7 Vangl2 Prkcg Csnk1a1 Dab2 Mapk3 Tfap2a Brd7 Jup Btrc Map1b Ctnnbip1 Prkcb Ankrd6 Rac1 Bcl9 Dlg1 Prkca Dlg2 Dlg4 Tcf4 Nr5a1 Camk2g Hipk2 Ppp2ca Camk2d Camk2b Gsk3b Cul1 Camk2a Csnk2a1 Arrb2 Mark2 Arrb1 Nlk Ctnnb1 Csnk2b Rhoa Ctbp1 Wnt5a Tmem97 Mapk1 Ctbp2 Mapk8ip1 Axin1 Axin2 Pax2 Lef1 Lrp6 Lrp5 Smad4 Wnt3a Dvl1 Dvl2 Dvl3 Raf1 Wnt7a Wnt2 Wnt4 Wnt3 Fzd2 Cdk1 Fzd4 Mapk9 Fzd9 Fzd8 CARDIOVASCULAR SIGNALING%WIKIPATHWAYS_20260810%WP590%RATTUS NORVEGICUS Cardiovascular signaling Pgf Thbs2 Akt1 Wasf1 Egf Rras2 Vav2 Col1a1 Map2k6 Col4a1 Pdgfra Vegfd Hspb1 Col4a2 Casp6 Hspa1b Stmn1 Casp3 Cfl1 Casp2 Arhgef7 Vwf Selenop Mapk8 Erbb2 Wnt2 Tnc Col11a1 Capn6 Col5a1 ATM SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP654%RATTUS NORVEGICUS ATM signaling pathway Sfnl1 Ccnd1 Ccnb1 Rb1 Chek2 Cdk6 Casp9 Casp3 Brca1 E2f1 Bax Tp53 Gadd45a Pmaip1 Ccne1 Cdk1 Cycs Necab3 Rprm Bak1 Cdkn1a PROSTAGLANDIN SYNTHESIS AND REGULATION%WIKIPATHWAYS_20260810%WP303%RATTUS NORVEGICUS Prostaglandin synthesis and regulation Anxa8 Anxa6 Ednrb Prl Ptgds S100a6 Scgb1a1 Ptgdr Tbxas1 Edn1 Ptgis Anxa1 Hpgd Anxa5 Ptger4 Anxa4 Anxa3 S100a10 Ptger2 Ptgs1 Ptgs2 Ptger3 Ptger1 Ptgfr Cyp11a1 Hsd11b1 Hsd11b2 Pla2g4a Ednra Ptgir SELENIUM MICRONUTRIENT NETWORK %WIKIPATHWAYS_20260810%WP1310%RATTUS NORVEGICUS Selenium micronutrient network Mtr Mt-co2 Alox5 Ptgds Cat Tbxas1 Gpx3 Ptgis Selenop Mthfr Selenok Xdh Gpx6 Fads2 Mt-co1 Gpx1 Kmo Fads1 Pnpo Sod1 OSTEOCLAST%WIKIPATHWAYS_20260810%WP489%RATTUS NORVEGICUS Osteoclast Ifnb1 Ifnar1 Itgb3 Slc9a1 Trpv5 Zcchc2 Tnfsf11 Ctsk Atp6v1e1 Spp1 SMALL LIGAND GPCRS%WIKIPATHWAYS_20260810%WP161%RATTUS NORVEGICUS Small ligand GPCRs Ptafr Ptgdr S1pr1 Ptger4 S1pr3 Ptger2 Cnr2 Ptger3 Ptger1 Ptgfr Lpar1 Mtnr1a Cnr1 Ptgir GPCRS CLASS B SECRETIN LIKE%WIKIPATHWAYS_20260810%WP378%RATTUS NORVEGICUS GPCRs class B secretin like Adgre5 Gipr Gcgr Adgre1 Sctr Adgrl4 Adcyap1r1 Adgrl1 Glp2r Vipr1 Adgrl2 Calcrl Adgrl3 Glp1r Crhr2 Ghrhr Crhr1 Calcr BETA OXIDATION META PATHWAY%WIKIPATHWAYS_20260810%WP372%RATTUS NORVEGICUS Beta oxidation meta pathway Gcdh Lpl Lipe Echs1 Crat Cpt2 Acads Pnpla2 Hadh Acadvl Cpt1a Hadha Gpd2 Hadhb Lipf Tpi1 Acsl4 Acadm Acsl1 Acat1 Dld Acsl5 Acsl6 Acsl3 MRNA PROCESSING%WIKIPATHWAYS_20260810%WP529%RATTUS NORVEGICUS mRNA processing Rnmt Snrnp70 Clp1 Snrpb2 Xrn2 Spop Prpf8 Snrnp40 Prpf18 Hnrnpr Dhx9 Hnrnpu Papola Snrpb Snrpa1 Snrpa Clk2 Clk3 Clk4 Mettl3 Prp4k Ptbp1 Fus Sugp1 Sugp2 Srpk1 Cpsf1 Hnrnpd Cpsf2 Cpsf3 Ddx1 Snrpepl2 Hnrnpk Hnrnpm Hnrnpab Cstf1 Ybx1 Clasrp Nudt21 Tmed10 Sfpq Prmt2 Cstf2 Dhx16 Cstf3 Srsf1 Ptbp2 Srsf9 Srsf7 Srsf6 Srsf5 Srsf4 Srsf3 Srsf2 Prmt1 Srek1 Srsf10 Srrm1 Rbm17 U2af1 Nxf1 Sf3a1 Sf3a2 Sf3a3 U2af2 Ncbp2 Ncbp1 Cd2bp2 Rbmx Snrpd1 Tra2b Celf4 Celf2 Pabpn1 Snrpd3 Sf3b2 Sf3b3 Sf3b4 Rbm39 Sfswap Sf3b5 Srp54 Hnrnph2 Ppm1g Hnrnph1 Dicer1 Ddx20 Rngtt Smc1a Celf1 Prpf4 Phf5a Prpf6 Prpf3 Prpf40a Scamp3 Hnrnpa2b1 Supt5h Cdc40 IL 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP569%RATTUS NORVEGICUS IL 2 signaling pathway Ets2 Akt1 Crkl Il2 Syk Rack1 Lck Crk Mapk14 Cxhxorf65 Il2ra Ptpn6 Ybx1 Il2rg Irs2 Socs3 Mtor Mapk8 Mapk3 Nr3c1 Jak2 Foxo3 Jak1 Eif3b Jak3 Gab2 Eif4e Prkcz Pik3r1 Pik3cd Pik3r2 Pik3ca Stam2 Cd53 Itm2b Pik3cg Stam Rps6kb1 Nmi Ptpn11 Shc1 Mapk1 Fyn Lyn Mknk1 Mapkapk2 Rela Map2k1 Ptk2b Plcb1 Nfkb1 Tert Grb2 Stat5a Stat5b Chuk Raf1 Sos1 Stat3 Mapk9 BIOSYNTHESIS OF ALDOSTERONE AND CORTISOL%WIKIPATHWAYS_20260810%WP508%RATTUS NORVEGICUS Biosynthesis of aldosterone and cortisol Hsd3b6 Cyp17a1 Cyp21a1 MATRIX METALLOPROTEINASES%WIKIPATHWAYS_20260810%WP278%RATTUS NORVEGICUS Matrix metalloproteinases Mmp24 Mmp14 Mmp15 Mmp16 Tnf Mmp28 Timp3 Timp2 Timp4 Bsg Tcf20 Mmp21 Mmp2 Mmp9 Mmp11 Cep295nl Mmp23 ETHANOL METABOLISM RESULTING IN PRODUCTION OF ROS BY CYP2E1%WIKIPATHWAYS_20260810%WP4268%RATTUS NORVEGICUS Ethanol metabolism resulting in production of ROS by CYP2E1 Mapk8 Mafg Cyp2e1 Nfe2l2 Map2k1 Prkcb RELATIONSHIP BETWEEN GLUTATHIONE AND NADPH%WIKIPATHWAYS_20260810%WP2562%RATTUS NORVEGICUS Relationship between glutathione and NADPH Gsn Map3k5 Ugp2 Anpep Pgm1 Pgm2 Dffa Dffb Alox5 Bax Fth1 Tp53 Mapk8 Gpi Abcc1 Pfkl Txn Eno1 Gclm Pgam2 Gapdh Pklr Pgk1 Ftl1 Ugdh Casp3 Gstp1 Nnt Ptgr1 Tfr2 Gapdhl6 Dpep2 Ugt8 Ltc4s Tfrc Gck Aldoa Rpia Rpe Nqo1 G6pdx Taldo1 Gss Pgls Kif1b Tkt Pgd Fas Cdkn1a INTRACELLULAR TRAFFICKING OF CFTR%WIKIPATHWAYS_20260810%WP1486%RATTUS NORVEGICUS Intracellular trafficking of CFTR Ezr Fblim1 Rab7a Rab11a Cftr Nherf1 THICK ASCENDING LIMB TRANSPORTERS%WIKIPATHWAYS_20260810%WP3882%RATTUS NORVEGICUS Thick ascending limb transporters Ca4 Slc12a7 Kcnj16 Clcnkb Clcnka Kcnq1 Slc4a7 Slc12a1 Atp1b1 Slc9a2 Slc9a3 Atp1a1 Aqp1 Kcnk12 Ca2 PEPTIDE GPCRS%WIKIPATHWAYS_20260810%WP131%RATTUS NORVEGICUS Peptide GPCRs Cxcr6 Tacr3 Cckar Tacr2 Tshr Tac4 Npy5r Tacr1 Ntsr2 Brs3 Mc2r Ccr7 Ccr6 Ccr3 Npy4r Oxtr Mc4r Npy2r Agtr2 Bdkrb2 Mc3r Cxcr1 Ednra Gnrhr Oprk1 Ntsr1 Fshr Ccr5 Ccr2 Ghsr Ednrb Cckbr Npy1r Sstr2 Oprd1 C3ar1 Cxcr4 Oprl1 Galr2 Galr3 Galr1 Lhcgr Sstr5 Sstr4 Grpr Sstr3 Sstr1 Avpr1b Mc5r Oprm1 Fpr1 Nmbr Fpr3 Bdkrb1 Fpr2 Ccr10 Agtr1 G1 TO S CELL CYCLE CONTROL%WIKIPATHWAYS_20260810%WP348%RATTUS NORVEGICUS G1 to S cell cycle control Mnat1 Pcna Ccna1 Ccne2 Ccnh Cdkn2b Tfdp1 Cdkn2c Cldn5 Myt1 Gadd45a Mcm4 Mcm6 Mcm2 Pole2 Pola2 Ccng2 Creb3l4 Creb3l1 Orc5 Atf6b Rpa3l1 Orc4 Orc6 Orc1 Orc3 Rpa2 Wee1 E2f2 Ccnd1 E2f3 E2f4 E2f6 Pole Cdkn1c Cdk7 E2f1 E2f5 Tp53 Cdkn1b Creb3 Ccnb1 Cdk6 Mcm7 Ccne1 Mcm5 Rb1 Rbl1 Mdm2 Cdk1 Necab3 Cdkn1a G13 SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP520%RATTUS NORVEGICUS G13 signaling pathway Pak3 Mapk10 Limk1 Pik3cd Rock2 Rock1 Pik3r2 Rps6kb1 Tnk2 Arhgdib Iqgap2 Ppp1cb Cdc42 Cfl2 Wasl Sh3rf1 Cit Diaph1 Cyfip1 Pip4k2a Mybph Arhgef1 Pkn1 Map3k4 Rac1 G PROTEIN SIGNALING PATHWAYS%WIKIPATHWAYS_20260810%WP73%RATTUS NORVEGICUS G protein signaling pathways Gna13 Prkaca Gnaq Gngt1 Gnb2 Gnb3 Prkd3 Gng13 Ppp3cc Itpr1 Gnb1 Hras Pde7b Gnai1 Pde7a Adcy3 Prkcq Akap7 Adcy4 Gnai3 Akap3 Adcy2 Akap4 Prkcg Akap1 Adcy7 Gnaz Akap10 Akap11 Adcy5 Akap12 Prkci Akap9 Nras Akap13 Prkcb Adcy9 Pde8a Prkce Pde8b Pde4b Kcnj3 Prkca Prkacb Pakap Prkar1a Gna14 Gnao1 Gnal Gng5 Pde4c Gnas Gng3 Pde1c Pde1a Gng11 Gna12 Prkcz Prkcd Pde4d Gng8 Prkar2b Akap8 Rhoa Ppp3ca Plcb3 Rras Adcy8 Arhgef1 Prkar1b Slc9a1 ACETYLCHOLINE SYNTHESIS%WIKIPATHWAYS_20260810%WP360%RATTUS NORVEGICUS Acetylcholine synthesis Ache Pcyt1a Ahsg Pdha1 Chat Pemt PROXIMAL TUBULE TRANSPORTERS%WIKIPATHWAYS_20260810%WP3881%RATTUS NORVEGICUS Proximal tubule transporters Ca4 Slc20a2 Slc22a6 Car15 Slc26a1 Fxyd4 Slc22a5 Tctn2 Atp6v0a2 Atp6v0a4 Atp6v1g3 Slc34a1 Atp6v0e2 Atp6v0a1 Slc1a1 Atp6v0c Car7 Slc4a4 Slc38a7 Atp6v1e1 Slc6a19 Slc7a6 Slc7a7 Slc9a8 Slc13a3 Slc7a8 Atp6v1a Slc13a1 Slc7a9 Slc34a2 Slc13a2 Atp6v1b2 Atp6v0d2 Atp6v0d1 Nherf2 Atp6v1b1 Nherf1 Slc16a10 Atp6v1g1 Slc22a8 Atp6v1d Ca14 Atp6v1h Atp1b1 Slc9a3 Atp1a1 Ca2 GENETIC ALTERATIONS OF LUNG CANCER%WIKIPATHWAYS_20260810%WP1968%RATTUS NORVEGICUS Genetic alterations of lung cancer Mapk1 Ccnd1 Rb1 Tgfb2 Egfr Crebbp Map2k1 Akt1 E2f1 Smad4 Tp53 Pik3cd Erbb2 Raf1 Pik3ca Dmp1 Mycb Rasl11b Smad2 Tgfb1 Mdm2 Ccne1 Necab3 Cdkn1a LIPID DROPLET METABOLISM%WIKIPATHWAYS_20260810%WP3901%RATTUS NORVEGICUS Lipid droplet metabolism Soat1 Agpat2 Plin2 Bscl2 Pnpla2 Gpd2 Acsl1 Aup1 Lpin3 Gpat2 Lipa Dgat2 Lpin1 Agpat5 Acsl3 Dgat1 Agpat3 Fitm2 Agpat4 Agpat1 FOLIC ACID NETWORK%WIKIPATHWAYS_20260810%WP1311%RATTUS NORVEGICUS Folic acid network Cbs Mtr Msrb1 Mt-co2 Alox5 Ptgds Cat Gpx3 Ptgis Txnrd2 Mthfr Selenok Xdh Gpx6 Fads2 Mt-co1 Gpx1 Kmo Selenow Pnpo Sod1 P53 PATHWAY%WIKIPATHWAYS_20260810%WP655%RATTUS NORVEGICUS p53 pathway Sesn1 Zmat3 Sfnl1 Serpinb5 Ccnb1 Chek2 Igfbp3 Cdkn2a Shisa5 Cdk6 Adgrb1 Cd82 Mdm4 Ppm1d Pten Rchy1 Ccng1 Gadd45a Ccne1 Cycs Tp73 Chek1 Casp9 Casp3 Bax Tp53 Tsc2 Siah1 Perp Pmaip1 Cdk1 Fas Bid Serpine1 Rprm Cdkn1a NUCLEAR RECEPTORS%WIKIPATHWAYS_20260810%WP217%RATTUS NORVEGICUS Nuclear receptors Nr5a1 Nr2e1 Hnf4a Nr2f1 Esrrb Nr2f6 Thrb Nr1d2 Thra Nr2f2 Rara Rorc Nr1h2 Esr2 Ror1 Nr5a2 Nr2c2 Nr4a2 Nr1i3 Rxra Nr1i2 Ppard Rarb Esr1 Rxrb Vdr Nr1h3 Ppara Pparg Rxrg Nr3c1 Esrra HYPERTROPHY MODEL%WIKIPATHWAYS_20260810%WP442%RATTUS NORVEGICUS Hypertrophy model Jund Ifng Eif4e Atf3 Eif4ebp1 Il1a Il1r1 Myog Wdr1 Ankrd1 Zeb1 Dusp14l1 Hbegf Ifrd1 Ccn1 Nr4a3 BURN WOUND HEALING%WIKIPATHWAYS_20260810%WP5057%RATTUS NORVEGICUS Burn wound healing Acta1 Gpr176 Ptgis Pdgfa Syk Col1a1 Il1b Col4a1 Ankrd1 Mmp9 Cdc25b Il10 Jun Arfgap1 Igf1 Ccn2 Epo Chp1 Syp Il1rl1 Glb1 Casp3 Adora2b Tp53 Dll4 HEDGEHOG SIGNALING PATHWAY%WIKIPATHWAYS_20260810%WP574%RATTUS NORVEGICUS Hedgehog signaling pathway Igf2 Ccnb1 Crebbp Hhip Gli1 Gli3 Gli2 Ski Shh Ptch2 Smo Ptch1 Sufu Sap18 Dyrk1a Cdk1