ISOLEUCINE BIOSYNTHESIS%PANTHER PATHWAY%P02748 Isoleucine biosynthesis Hacl2 Bcat1 Bcat2 PENTOSE PHOSPHATE PATHWAY%PANTHER PATHWAY%P02762 Pentose phosphate pathway Rpia Gpi Taldo1 Tkt Hk2 ANANDAMIDE_DEGRADATION%PANTHER PATHWAY%P05728 Anandamide_degradation FORMYLTETRAHYDROFORMATE BIOSYNTHESIS%PANTHER PATHWAY%P02743 Formyltetrahydroformate biosynthesis Dhfr Mthfd1l Tyms Mtr Mthfd2 FRUCTOSE GALACTOSE METABOLISM%PANTHER PATHWAY%P02744 Fructose galactose metabolism Galt Aldob Aldoc Aldoa Khk Hk2 Gale P38 MAPK PATHWAY%PANTHER PATHWAY%P05918 p38 MAPK pathway Atf1 Traf6 Srf Mef2d Elk1 Map3k7 Map2k6 Map3k4 Hspb1 Mapk12 Mapkapk3 Mapk13 Mapk14 Mapkapk2 Eef2k Eif4e Map2k4 Rps6ka5 Mef2c Mknk2 Mknk1 Tab2 Map3k10 Il1r1 Mapk11 VEGF SIGNALING PATHWAY%PANTHER PATHWAY%P00056 VEGF signaling pathway Lpxn Arhgap8 Shc2 Pxn Hif1a Vegfa Pik3cg Prkcz Pik3cb Pik3cd Casp9 Nos3 Pik3c2b Pik3c2a Ptk2 Map2k2 Tgfb1i1 Map2k1 Hras Hspb1 Mapkapk3 Mapk14 Mapkapk2 Prr5 Prkd3 Mapk1 Pla2g4a Prkd1 Braf Prkd2 Ets1 Pik3c3 Mapk3 Cryab Rac2 Akt1 Rac1 Sh2d2a Plcg1 Araf Prkcq Plcg2 Prkcg Prkch Prkci Nras Prkcb Sphk2 Arhgap1 Prkcd Sphk1 Prkce Prkca Raf1 Pik3r1 Pik3r2 Pik3r3 INTERLEUKIN SIGNALING PATHWAY%PANTHER PATHWAY%P00036 Interleukin signaling pathway Pik3cb Nos3 Il10 Ikbkb Spi1 Cxcr1 Stat6 Il15 Irs1 Cxcr2 Stat4 Il13 Il18 Il2ra Irs2 Sla2 Mapk6 Elk4 Pdpk1 Akt3 Myc Akt2 Jak3 Foxo3 Il13ra1 Il13ra2 Fos Il20ra Il23a Gsk3b Rps6ka3 Rps6ka6 Rps6ka1 Rps6ka2 Il5ra Sos1 Il6st Shc1 Il10rb Il3ra Mtor Il2 Il4 Il6 Il5 Il7 Il9 Il6r Il21 Il12rb2 Il11ra1 Il4r Mapk15 Spic Srf Il1a Stat5a Elk1 Stat5b Stat3 Stat2 Stat1 Chuk Cdkn1a Cdkn1b Mapkapk2 Mknk2 Mknk1 Mapk1 Braf Mapk3 Akt1 Araf Nras Raf1 FLAVIN BIOSYNTHESIS%PANTHER PATHWAY%P02741 Flavin biosynthesis HEME BIOSYNTHESIS%PANTHER PATHWAY%P02746 Heme biosynthesis Alad Qars1 Hmbs Fech Eprs1 Cpox Urod Ppox NICOTINE PHARMACODYNAMICS PATHWAY%PANTHER PATHWAY%P06587 Nicotine pharmacodynamics pathway Cacna1g Cacna1c Epb41l2 Chrnb4 Clic6 Ppp1r1b Kcnk3 Chrnb3 Chrnb2 Epb41l1 Slc18a2 Adcy2 Drd2 Drd4 Ppp1ca Prkaca Kcnk9 Chrna3 Epb41 Chrna6 Chrna5 Chrna4 Gnb1 Flna Gnai1 CIRCADIAN CLOCK SYSTEM%PANTHER PATHWAY%P00015 Circadian clock system Per2 Per1 Per3 Cry1 Cry2 Clock Csnk1d Csnk1e Bmal1 CHOLESTEROL BIOSYNTHESIS%PANTHER PATHWAY%P00014 Cholesterol biosynthesis Mvd Fdft1 Lss Fdps Sqle Hmgcs1 Pmvk Ggps1 Hmgcr IONOTROPIC GLUTAMATE RECEPTOR PATHWAY%PANTHER PATHWAY%P00037 Ionotropic glutamate receptor pathway Grin2a Shank1 Shank3 Grm2 Slc1a1 Slc1a3 Slc1a2 Grin1 Slc1a7 Slc17a8 Slc1a6 Slc17a6 Vamp8 Vamp1 Gria4 Vamp3 Gria3 Vamp2 Snap29 Gria2 Snap25 Grik5 Snap23 Stx19 Grik2 Grik1 Grik4 Grik3 Grin2d Grin2c Grin2b Stx11 PYRIDOXAL-5-PHOSPHATE BIOSYNTHESIS%PANTHER PATHWAY%P02759 Pyridoxal-5-phosphate biosynthesis Psat1 CELL CYCLE%PANTHER PATHWAY%P00013 Cell cycle Ccnd2 Ccnd3 Ccne1 Cinp P53 PATHWAY FEEDBACK LOOPS 2%PANTHER PATHWAY%P04398 p53 pathway feedback loops 2 Pik3cg Pik3cb Pik3cd Pik3c2b Pik3c2a Mapk12 Cdkn1a Mapk13 Mapk14 Hras Mapk11 Pdpk1 Akt3 Ccne1 Pik3c3 Akt2 Ccng1 Ctnnb1 Akt1 Kras Tp53 Tp73 Ppp2cb Rb1 Ppp2ca Pten Pik3c2g Rbl1 Siah1 Nras Cdk2 Pik3r5 Atm Tp63 Atr Pik3r1 Pik3r2 Pik3r3 THREONINE BIOSYNTHESIS%PANTHER PATHWAY%P02781 Threonine biosynthesis Thnsl1 AMINOBUTYRATE DEGRADATION%PANTHER PATHWAY%P02726 Aminobutyrate degradation Abat HISTAMINE H1 RECEPTOR MEDIATED SIGNALING PATHWAY%PANTHER PATHWAY%P04385 Histamine H1 receptor mediated signaling pathway Plcd1 Plcb2 Plcd4 Plcb1 Hrh1 Gng3 Gng5 Plcl1 Prkcz Gng7 Gnaq Gng8 Gngt2 Plcz1 Plce1 Gnb2 Gnb4 Gnb3 Gnb5 Itpr3 Itpr2 Itpr1 Plcg1 Gnb1 Prkcq Plcg2 Prkcg Prkch Prkci Prkcb Prkcd Prkce Plcb4 Prkca Plcb3 Gna11 Gng10 Gna14 METABOTROPIC GLUTAMATE RECEPTOR GROUP I PATHWAY%PANTHER PATHWAY%P00041 Metabotropic glutamate receptor group I pathway Grin2c Grin2b Grin2a Prkaca Gnaq Grin1 Itpr1 Prkar1b Prkcb Prkx Prkacb Grina Grik5 Grm1 Grm5 Plcb4 Grik1 Gna11 Grin2d OXIDATIVE STRESS RESPONSE%PANTHER PATHWAY%P00046 Oxidative stress response Txn Pla2g4a Map2k3 Bcl2 Myc Elk1 Map2k6 Stat1 Mapk12 Mapk13 Mapk14 Eef2k Map2k4 Mef2c Mknk2 Mknk1 Mapk9 Jun Mapk8 Mapk11 Max Ddit3 5HT1 TYPE RECEPTOR MEDIATED SIGNALING PATHWAY%PANTHER PATHWAY%P04373 5HT1 type receptor mediated signaling pathway Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb4 Gnb3 Gnb5 Prkx Prkacb Kcnk3 Gnao1 Adcy2 Adcy7 Prkar2a Prkar2b Prkaca Htr1d Kcnk9 Htr1f Gnai2 Htr1b Htr1a Gng11 Gnai3 Gnb1 Gnai1 Gng10 OXYTOCIN RECEPTOR MEDIATED SIGNALING PATHWAY%PANTHER PATHWAY%P04391 Oxytocin receptor mediated signaling pathway Plcd1 Plcb2 Plcd4 Plcb1 Gng3 Gng5 Plcl1 Prkcz Gng7 Gnaq Gng8 Gngt2 Plcz1 Plce1 Gnb2 Gnb4 Gnb3 Gnb5 Plcg1 Oxtr Gnb1 Prkcq Plcg2 Prkcg Prkch Prkci Prkcb Prkcd Prkce Plcb4 Prkca Plcb3 Gna11 Gng10 Gna14 5HT4 TYPE RECEPTOR MEDIATED SIGNALING PATHWAY%PANTHER PATHWAY%P04376 5HT4 type receptor mediated signaling pathway Adcy2 Adcy7 Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb1 Htr4 Gnb4 Gnal Gnb3 Gnb5 Gng10 GABA-B_RECEPTOR_II_SIGNALING%PANTHER PATHWAY%P05731 GABA-B_receptor_II_signaling Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb4 Gnb3 Prkar1b Prkacb Cacna1g Gnao1 Adcy2 Adcy7 Prkar2a Prkar2b Prkaca Gng11 Gnai3 Gnb1 Gnai1 Cacna1a Cacna1b Gabbr1 Gabbr2 Adcy4 Adcy8 Adcy5 Adcy6 Kcnj3 UBIQUITIN PROTEASOME PATHWAY%PANTHER PATHWAY%P00060 Ubiquitin proteasome pathway Ube2n Ube2c Ube2b Uba1 Ube2d3 Uba2 Ube2d2 Uba3 Ube2d1 Ube2e2 Ube2g2 Ube2l6 Ube2g1 Ube2a Atg7 Sae1 Ube2l3 Ube2t Ube2s Ube2v2 Ube2k Uba6 Ube2d2b ALZHEIMER DISEASE-PRESENILIN PATHWAY%PANTHER PATHWAY%P00004 Alzheimer disease-presenilin pathway App Erbb4 Apbb3 Nectin1 Trpc6 Afdn Trpc5 Trpc7 Kat5 Wnt5a Trpc1 Cdh1 Trpc4 Wnt5b Wnt9a Kat7 Wnt9b Bace2 Bace1 Wnt10b Acta1 Actb Actr2 Ern1 Ctnnb1 Psenen Notch1 Notch2 Notch3 Psen1 Gsk3b Psen2 Wnt8a Fstl1 Lef1 Wnt11 Ncstn Aph1b Lrp1 Lrp6 Lrp2 Lrp3 Lrp4 Lrp5 Wnt6 Rbpjl Wnt7b Wnt3a Dvl1 Dvl3 Wnt7a Wnt2 Tcf7l1 Wnt1 Wnt4 Cd44 Actg1 Actg2 Wnt3 Tcf7l2 Fzd1 Actbl2 Actc1 Fzd2 Jup Fzd5 Trim3 Fzd4 Fzd6 Fzd9 Fzd8 5-HYDROXYTRYPTAMINE DEGREDATION%PANTHER PATHWAY%P04372 5-Hydroxytryptamine degredation Aldh7a1 Aldh9a1 Aldh1l2 Aldh1b1 Aldh1a2 Aldh1a1 Maob Aldh3a2 Aldh2 Aldh3a1 Aldh1a3 Aldh16a1 Aldh8a1 P53 PATHWAY FEEDBACK LOOPS 1%PANTHER PATHWAY%P04392 P53 pathway feedback loops 1 Mdm2 Mdm4 Tp63 Tp53 Tp73 VALINE BIOSYNTHESIS%PANTHER PATHWAY%P02785 Valine biosynthesis Hacl2 Bcat1 Bcat2 ACETATE UTILIZATION%PANTHER PATHWAY%P02722 Acetate utilization Acss3 Acss1 COENZYME A BIOSYNTHESIS%PANTHER PATHWAY%P02736 Coenzyme A biosynthesis Pank3 Pank4 Pank1 Dcakd METHYLCITRATE CYCLE%PANTHER PATHWAY%P02754 Methylcitrate cycle Ireb2 Aco1 B CELL ACTIVATION%PANTHER PATHWAY%P00010 B cell activation Pik3cg Pik3cb Pik3cd Map2k2 Map2k1 Hras Ikbkb Fos Sos1 Chuk Mapk12 Mapk13 Mapk14 Itpr3 Itpr2 Itpr1 Mapk9 Jun Mapk8 Mapk11 Mapk1 Mapk3 Rac2 Rac1 Nfkbil1 Cd22 Araf Vav3 Syk Plcg2 Vav1 Vav2 Map3k3 Map3k2 Nras Prkcb Blnk Btk Cd79b Prkcd Ptpn6 Lyn Ptprc Ppp3ca Raf1 Ppp3cb Nfkbia Grb2 Mapk10 P53 PATHWAY BY GLUCOSE DEPRIVATION%PANTHER PATHWAY%P04397 p53 pathway by glucose deprivation Eif4ebp1 Tsc2 Tsc1 Igbp1 Prkaa1 Akt3 Prkab2 Rps6kb1 Akt2 Prkaa2 Prkab1 Prkag1 Akt1 Tp53 Tp73 Ppp2cb Ppp2ca Tp63 5-ARACHIDONYLGLYCEROL_BIOSYNTHESIS%PANTHER PATHWAY%P05726 5-arachidonylglycerol_biosynthesis Plcb2 Plcb1 Dagla Lpl Plcb3 Pla1a MANNOSE METABOLISM%PANTHER PATHWAY%P02752 Mannose metabolism Pmm1 Mpi Gmppa Pmm2 Gmds MRNA SPLICING%PANTHER PATHWAY%P00058 mRNA splicing Snrnp40 Zrsr2 Prpf3 Snrpb2 Snrpa HYPOXIA RESPONSE VIA HIF ACTIVATION%PANTHER PATHWAY%P00030 Hypoxia response via HIF activation Txn Hif1a Akt3 Akt2 Akt1 Rorc Arnt Mtor Txn2 Crebbp Egln2 Egln3 Vhl THIAMINE METABOLISM%PANTHER PATHWAY%P02780 Thiamine metabolism Thtpa Tpk1 TRANSCRIPTION REGULATION BY BZIP TRANSCRIPTION FACTOR%PANTHER PATHWAY%P00055 Transcription regulation by bZIP transcription factor Taf7 Taf6 Gtf2e1 Taf2 Prkar1b Crebbp Gtf2a1l Polr2c Taf1c Taf9 Creb3l3 Creb3l4 Prkar2a Polr2h Prkar2b Polr2e Creb3l1 Ttf2 Creb3l2 Polr2f Taf9b Taf11 Gtf2h1 Psmc3ip Gtf2f2 Gtf2h4 Gtf2f1 Gtf2h3 Brf2 Tbp Brf1 Tbpl2 Tbpl1 Creb5 Gtf2a1 Gtf2a2 Mterf2 Gtf2b Polr2sl1 Taf8 OPIOID PROOPIOMELANOCORTIN PATHWAY%PANTHER PATHWAY%P05917 Opioid proopiomelanocortin pathway Gnao1 Adcy2 Oprd1 Adcy7 Gng3 Pomc Gng5 Gng7 Gnai2 Gng8 Gngt2 Gnai3 Gnb2 Gnb1 Gnb4 Gnai1 Gnb3 Gnb5 Gng10 BUPROPION_DEGRADATION%PANTHER PATHWAY%P05729 Bupropion_degradation Cyp2b2 O-ANTIGEN BIOSYNTHESIS%PANTHER PATHWAY%P02757 O-antigen biosynthesis Tgds Gfpt1 Gfpt2 VASOPRESSIN SYNTHESIS%PANTHER PATHWAY%P04395 Vasopressin synthesis Avp Oxt GLUTAMINE GLUTAMATE CONVERSION%PANTHER PATHWAY%P02745 Glutamine glutamate conversion Lgsn Glud1 UNTITLED%PANTHER PATHWAY%P00019 untitled Prkcz Nos3 Map2k2 Map2k1 Akt3 Akt2 Plcb4 Plcb3 Gna11 Gna14 Plcb2 Plcb1 Gnaq Ednrb Ednra Adcy3 Edn1 Edn2 Itpr3 Edn3 Itpr2 Adcy10 Itpr1 Prkar1b Gucy1b1 Prkg2 Prkacb Gucy1a1 Gucy1a2 Mapk1 Pla2g4a Adcy2 Adcy7 Prkar2a Prkar2b Mapk3 Prkaca Akt1 Araf Prkcq Gnal Prkcg Prkch Prkci Adcy4 Prkcb Adcy8 Adcy5 Adcy6 Prkcd Prkce Prkca Raf1 HISTAMINE SYNTHESIS%PANTHER PATHWAY%P04387 Histamine synthesis Hdc TETRAHYDROFOLATE BIOSYNTHESIS%PANTHER PATHWAY%P02742 Tetrahydrofolate biosynthesis Dhfr Gch1 Tyms 5HT2 TYPE RECEPTOR MEDIATED SIGNALING PATHWAY%PANTHER PATHWAY%P04374 5HT2 type receptor mediated signaling pathway Plcd1 Plcb2 Plcd4 Plcb1 Gng3 Gng5 Plcl1 Prkcz Gng7 Gnaq Gng8 Gngt2 Plcz1 Plce1 Gnb2 Gnb4 Gnb3 Gnb5 Htr2a Htr2c Htr2b Gng11 Plcg1 Gnb1 Prkcq Plcg2 Prkcg Prkch Prkci Prkcb Prkcd Prkce Plcb4 Prkca Plcb3 Gna11 Gng10 Gna14 INTEGRIN SIGNALLING PATHWAY%PANTHER PATHWAY%P00034 Integrin signalling pathway Itga2 Itga10 Col4a3 Pxn Arpc3 Col4a1 Cav1 Pik3cg Arpc2 Col4a2 Pik3cb Col8a1 Pik3cd Col4a5 Arpc5 Parvb Pik3c2b Parva Pik3c2a Rap2b Ptk2 Col16a1 Arf1 Map2k2 Col12a1 Itgax Map2k1 Ilk Hras Itgav Rnd2 Rnd3 Rhoa Rnd1 Rhob Itgam Asap1 Itgal Arhgap10 Rap1a Col3a1 Rap1b Itgad Mapk6 Itgb8 Itgb6 Itgb7 Itgb1 Itga2b Actb Itgb4 Rras Itgb2 Actn1 Actn4 Crk Arf6 Arhgap26 Col11a1 Col11a2 Src Dock1 Bcar1 Dnajc27 Sos1 Lamb2 Lamb3 Shc1 Ptpn12 Fyn Csk Lamb1 Col2a1 Col27a1 Col6a2 Ptk2b Lims2 Lamc1 Actg1 Actbl2 Flna Map3k3 Map3k2 Mapk10 Map3k4 Mapk13 Map2k4 Mapk9 Mapk8 Col14a1 Itgbl1 Crkl Arfgap1 Map2k3 Col1a2 Col5a2 Braf Col5a3 Col5a1 Dmbt1 Pik3c3 Mapk3 Col9a2 Col9a1 Arpc1b Rac2 Lama5 Arpc1a Rac1 Lama1 Lama3 Araf Lama4 Flnb Tln1 Vcl Vasp Col17a1 Nras Col13a1 Itga7 Fn1 Itga8 Arl1 Itga5 Itga6 Itga9 Raf1 Itga3 Elmo2 Pik3r1 Itga1 Pik3r2 Elmo1 Pik3r3 PDGF SIGNALING PATHWAY%PANTHER PATHWAY%P00047 PDGF signaling pathway Arhgap8 Shc2 Pik3cg Pik3cb Pik3cd Map2k2 Map2k1 Hras Ikbkb Stat6 Stat4 Arhgap10 Mapk6 Elk4 Pdpk1 Myc Akt2 Jak3 Fos Arhgap26 Gsk3b Rps6ka3 Rps6ka6 Rps6ka1 Rps6ka2 Sos1 Shc1 Ehf Srgap1 Srgap3 Rab11b Arhgap5 Arhgap4 Mapk15 Erf Erg Arhgap9 Stat5a Shc3 Stat5b Rasa2 Stat3 Rasa1 Stat2 Pdgfrb Stat1 Pdgfra Chuk Pdgfa Pdgfrl Pdgfb Grap Fli1 Rps6kc1 Fev Gabpa Nck2 Jak2 Jak1 Nck1 Arhgap15 Arhgap12 Gab1 Gab2 Etv3 Spdef Elf1 Elf2 Gsk3a Elf3 Elf4 Elf5 Ophn1 Usf2 Grap2 Elp1 Rerg Nin Pkn2 Ninl Arhgap42 Vav3 Vav1 Vav2 Map3k2 Grb2 Mapk10 Rps6kb1 Pik3r5 Srf Elk1 Map3k4 Itpr3 Mapkapk2 Itpr2 Itpr1 Rps6ka5 Mknk2 Mknk1 Jun Mapk8 Mapk1 Braf Ets1 Pik3c3 Mapk3 Plcg1 Araf Plcg2 Nras Arhgap1 Prkca Raf1 Pik3r1 Pik3r2 Pik3r3 NICOTINIC ACETYLCHOLINE RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P00044 Nicotinic acetylcholine receptor signaling pathway Myo5c Myo5b Myo1a Myh11 Myo1g Myo1f Plekhh3 Myh10 Myh7b Myo6 Myo18b Myo5a Myo9a Slc5a7 Chrnd Chrne Chrng Chrna2 Chrna1 Myo10 Chrna9 Myo15a Myo16 Myo19 Acta1 Actb Actg1 Actg2 Actbl2 Actc1 Chrnb4 Chrnb3 Chrnb2 Chrna3 Chrna6 Chrna5 Chrna4 Slc44a3 Actr1a Myo3b Chrnb1 Myo7a Slc18a3 Myo7b Slc6a8 Chrna10 Myh2 Myh3 Myh4 Myh7 Myo1c Myo1b Myo1e Myo1d JAK STAT SIGNALING PATHWAY%PANTHER PATHWAY%P00038 JAK STAT signaling pathway Stat6 Jak3 Jak2 Stat5a Jak1 Stat5b Stat3 Stat4 Stat1 CARNITINE METABOLISM%PANTHER PATHWAY%P02733 Carnitine metabolism SERINE GLYCINE BIOSYNTHESIS%PANTHER PATHWAY%P02776 Serine glycine biosynthesis Psat1 Phgdh Psph AXON GUIDANCE MEDIATED BY NETRIN%PANTHER PATHWAY%P00009 Axon guidance mediated by netrin Pik3cg Pik3cb Pik3cd Pik3c2b Pik3c2a Ntn1 Ntn3 Nfatc4 Nfatc3 Nfatc2 Ablim1 Dcc Ntng1 Unc5b Unc5d Unc5c Rac2 Rac1 Plcg1 Plcg2 Vasp Pik3r5 Pik3r1 Pik3r2 Pik3r3 ADRENALINE AND NORADRENALINE BIOSYNTHESIS%PANTHER PATHWAY%P00001 Adrenaline and noradrenaline biosynthesis Slc18a2 Slc6a19 Slc6a18 Slc6a15 Slc6a20a Slc6a16 Slc18a1 Slc6a2 Slc6a3 NICOTINE_DEGRADATION%PANTHER PATHWAY%P05914 Nicotine_degradation Ugt1a2 Ugt1a3 Inmt Ugt1a5 Ugt2b7 Fmo3 Cyp2a3 COENZYME A LINKED CARNITINE METABOLISM%PANTHER PATHWAY%P02732 Coenzyme A linked carnitine metabolism S-ADENOSYLMETHIONINE BIOSYNTHESIS%PANTHER PATHWAY%P02773 S-adenosylmethionine biosynthesis Mat2a Mat1a Mtr CYTOSKELETAL REGULATION BY RHO GTPASE%PANTHER PATHWAY%P00016 Cytoskeletal regulation by Rho GTPase Myh11 Arpc3 Arpc2 Myh10 Myh7b Arpc5 Acta1 Actb Diaph2 Diaph1 Tubb2b Tubb2a Cfl1 Cfl2 Mylk2 Pfn1 Mylk3 Pfn3 Pfn2 Stmn1 Pak1 Pak6 Stmn4 Pak3 Pak2 Actg1 Pak5 Actg2 Pak4 Tubb5 Tubb6 Tubb3 Actbl2 Mylk Actc1 Limk1 Arpc4 Rock2 Tubb4b Rock1 Rac2 Arpc1b Rac1 Arpc1a Myo3b Myh2 Myh3 Myh4 Myh7 INSULIN IGF PATHWAY-MITOGEN ACTIVATED PROTEIN KINASE KINASE MAP KINASE CASCADE%PANTHER PATHWAY%P00032 Insulin IGF pathway-mitogen activated protein kinase kinase MAP kinase cascade Rps6kb1 Elk1 Rasa1 Map2k2 Map2k1 Ins2 Insr Igf2r Igf2 Igf1 Rps6ka5 Insrr Igf1r Irs1 Irs2 Mapk1 Map2k3 Mapk3 Fos Rps6ka3 Rps6ka6 Rps6ka1 Rps6ka2 Sos1 Raf1 INTERFERON-GAMMA SIGNALING PATHWAY%PANTHER PATHWAY%P00035 Interferon-gamma signaling pathway Jak2 Jak1 Ifngr2 Ifng Ifngr1 Stat1 5-HYDROXYTRYPTAMINE BIOSYNTHESIS%PANTHER PATHWAY%P04371 5-Hydroxytryptamine biosynthesis Tph2 Ddc Tph1 SALVAGE PYRIMIDINE RIBONUCLEOTIDES%PANTHER PATHWAY%P02775 Salvage pyrimidine ribonucleotides Upp2 Uprt Nme3 Nme2 Uck1 Uck2 Uckl1 Upp1 METABOTROPIC GLUTAMATE RECEPTOR GROUP III PATHWAY%PANTHER PATHWAY%P00039 Metabotropic glutamate receptor group III pathway Grin2a Slc1a1 Slc1a3 Slc1a2 Grin1 Slc1a7 Slc1a6 Vamp8 Vamp1 Gria4 Vamp3 Gria3 Vamp2 Snap29 Gria2 Snap25 Grik5 Snap23 Grik2 Grik1 Grik4 Grik3 Grin2d Grin2c Grin2b Gng10 Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb4 Gnb3 Gnb5 Adcy10 Prkar1b Prkx Prkacb Grm1 Grm5 Prkar2a Prkar2b Cacna1e Prkaca Grm4 Grm7 Gnai2 Grm6 Grm8 Vti1a Gnai3 Slc17a7 Stx1b Gnb1 Cacnb1 Gnai1 Stx1a Cacna1a Cacna1b APOPTOSIS SIGNALING PATHWAY%PANTHER PATHWAY%P00006 Apoptosis signaling pathway Xiap Endog Rela Map3k1 Apaf1 Tnfrsf10b Lta Pik3cg Fadd Atf7 Pik3cb Ltb Pik3cd Atf6 Casp9 Atf4 Atf3 Jdp2 Aifm1 Map2k7 Gzmf Map4k3 Atf6b Cradd Ikbkb Bak1 Eif2s1 Casp8 Casp7 Prkra Casp3 Bik Ripk1 Map4k2 Diablo Bax Rel Fas Faslg Daxx Map3k14 Akt3 Akt2 Tp53 Fos Atf1 Chuk Igf2r Map2k4 Mapk9 Jun Mapk8 Mapk1 Map2k3 Bcl2 Mapk3 Akt1 Prkcq Atf2 Prkcg Birc3 Prkch Eif2ak2 Birc2 Tnf Prkcb Madd Bcl2l11 Tnfrsf1b Prkcd Tnfrsf1a Tradd Prkce Nfkb2 Prkca Nfkb1 Traf2 Nfkbia Cycs Bcl2l1 Mapk10 LEUCINE BIOSYNTHESIS%PANTHER PATHWAY%P02749 Leucine biosynthesis Bcat1 Bcat2 RAS PATHWAY%PANTHER PATHWAY%P04393 Ras Pathway Map3k1 Pik3cg Pik3cb Pik3cd Map2k7 Map2k2 Map2k1 Hras Rhoa Rhob Pdpk1 Tiam1 Akt3 Ralgdsl1 Rala Ralb Exoc2 Pld1 Pld2 Kras Ralgds Gsk3b Rps6ka3 Rps6ka6 Rps6ka1 Rps6ka2 Sos1 Shc1 Pak1 Pak3 Pak2 Srf Elk1 Stat3 Map2k6 Map3k4 Stat1 Mapk12 Mapkapk3 Mapk13 Mapk14 Mapkapk2 Map2k4 Mapk9 Jun Mapk8 Mapk11 Mapk1 Map2k3 Gsk3a Braf Ets1 Pik3c3 Mapk3 Rac2 Akt1 Rac1 Araf Atf2 Nras Raf1 Grb2 Mapk10 ANGIOTENSIN_II-STIMULATED_SIGNALING_THROUGH_G_PROTEINS_AND_BETA-ARRESTIN%PANTHER PATHWAY%P05911 Angiotensin_II-stimulated_signaling_through_G_proteins_and_beta-arrestin Plcb2 Plcb1 Gng3 Gng7 Elk1 Gnaq Gng8 Gngt2 Gnb2 Map2k2 Gnb4 Gnb3 Map2k1 Gnb5 Itpr3 Itpr2 Itpr1 Mapk1 Mapk3 Grk3 Gng11 Grk2 Arrb2 Gnb1 Arrb1 Egr1 Agtr1 Agt Prkca Plcb3 Raf1 Gng10 GENERAL TRANSCRIPTION REGULATION%PANTHER PATHWAY%P00023 General transcription regulation Taf7 Taf6 Gtf2e1 Taf2 Gtf2a1l Polr2c Taf1c Taf9 Polr2h Polr2f Taf9b Taf11 Gtf2h1 Gtf2f2 Gtf2h4 Gtf2f1 Gtf2h3 Brf2 Brf1 Tbpl1 Gtf2a1 Gtf2a2 Mterf2 Gtf2b Taf8 P53 PATHWAY%PANTHER PATHWAY%P00059 p53 pathway Sirt1 Cdc25c Cdkn1a Crebbp Pdpk1 Mdm2 Akt3 Mdm4 Ccne1 Akt2 Akt1 Tp53 Tp73 Pten Gadd45g Sumo2 Cdk2 Chek2 Sumo3 Atm Gadd45b Tp63 Gadd45a Atr Hdac1 Sfn Cdkn2a Mta2 Traf2 Ccnb1 Gtse1 Cdk1 THYROTROPIN-RELEASING HORMONE RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P04394 Thyrotropin-releasing hormone receptor signaling pathway Prkcz Vamp8 Vamp1 Vamp3 Vamp2 Snap29 Snap25 Snap23 Plcb4 Plcb3 Gna11 Gng10 Gna14 Plcd1 Plcb2 Trh Plcd4 Plcb1 Trhr Stx3 Gng3 Cga Gng5 Cacnb3 Plcl1 Cacnb4 Gng7 Cacnb2 Gnaq Tshb Gng8 Gngt2 Plcz1 Plce1 Gnb2 Gnb4 Gnb3 Gnb5 Cacna1e Plcg1 Gnb1 Prkcq Cacnb1 Plcg2 Cacna1a Prkcg Cacna1b Prkch Prkci Prkcb Prkcd Prkce Prkca ANDROGEN ESTROGENE PROGESTERONE BIOSYNTHESIS%PANTHER PATHWAY%P02727 Androgen estrogene progesterone biosynthesis Hsd17b2 Lipa Cyp19a1 Hsd17b7 Hsd17b6 Soat2 Hsd17b3 Soat1 Hsd17b1 CADHERIN SIGNALING PATHWAY%PANTHER PATHWAY%P00012 Cadherin signaling pathway Wnt5a Cdh1 Wnt5b Wnt9a Wnt9b Wnt10b Acta1 Actb Actr2 Wnt8a Fstl1 Lef1 Wnt11 Wnt6 Wnt7b Wnt3a Wnt7a Wnt2 Tcf7l1 Wnt1 Wnt4 Actg1 Actg2 Wnt3 Tcf7l2 Fzd1 Actbl2 Actc1 Fzd2 Fzd5 Fzd4 Pcdhb2 Fzd6 Pcdhb1 Fzd9 Cdh9 Fzd8 Cdh8 Cdh7 Cdh6 Cdh5 Pcdhgb7 Pcdh10 Cdh2 Pcdh19 Pcdh18 Pcdh15 Pcdha1 Pcdhga11 Pcdhga10 Pcdhga12 Pcdha7 Pcdha6 Pcdha8 Pcdha3 Pcdha2 Pcdha5 Pcdha4 Pcdhgc3 Cdh24 Cdh23 Cdh20 Celsr3 Celsr1 Pcdhb10 Celsr2 Pcdh20 Fer Fat2 Fat1 Fat3 Pcdhb22 Pcdhac2 Cdhr2 Pcdha13 Cdhr1 Pcdha10 Pcdha11 Pcdh1 Cdh19 Cdh18 Cdh17 Pcdh11x Cdh16 Cdh15 Cdh13 Cdh12 Cdh11 Cdh10 Ptpn1 Pcdh8 Pcdh7 Pcdh9 Pcdhga5 Pcdhga7 Pcdhga8 Pcdhga1 Ctnnd2 Pcdhga2 Ctnnd1 Pcdhga3 Ctnnb1 UNTITLED%PANTHER PATHWAY%P06664 untitled Rela Tgif1 Skil PHENYLETHYLAMINE DEGRADATION%PANTHER PATHWAY%P02766 Phenylethylamine degradation Aoc3 Aoc1 TCA CYCLE%PANTHER PATHWAY%P00051 TCA cycle Aco2 Sdhc Pdk2 Cs Fh Pdha2 Suclg1 Mdh1 Ogdh ATP SYNTHESIS%PANTHER PATHWAY%P02721 ATP synthesis Atp5f1b Atp5f1c ORNITHINE DEGRADATION%PANTHER PATHWAY%P02758 Ornithine degradation Odc1 Azin1 SUCCINATE TO PROPRIONATE CONVERSION%PANTHER PATHWAY%P02777 Succinate to proprionate conversion Pccb Echdc1 LIPOATE_BIOSYNTHESIS%PANTHER PATHWAY%P02750 Lipoate_biosynthesis Lias PYRIMIDINE METABOLISM%PANTHER PATHWAY%P02771 Pyrimidine Metabolism Aldh6a1 Dpys Dpyd Dpysl2 Abat Dpysl3 Cda Upb1 Dpysl5 Nt5e ASCORBATE DEGRADATION%PANTHER PATHWAY%P02729 Ascorbate degradation Rpe BETA1 ADRENERGIC RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P04377 Beta1 adrenergic receptor signaling pathway Adcy2 Adcy7 Prkar2a Gng3 Prkar2b Gng5 Prkaca Gng7 Gng8 Gngt2 Gnb2 Gnb1 Gnb4 Gnal Gnb3 Gnb5 Adrb1 Prkx Prkacb Gng10 INSULIN IGF PATHWAY-PROTEIN KINASE B SIGNALING CASCADE%PANTHER PATHWAY%P00033 Insulin IGF pathway-protein kinase B signaling cascade Tsc2 Tsc1 Gsk3a Pdpk1 Mdm2 Mdm4 Foxo3 Gsk3b Pten Ins2 Insr Igf2r Igf2 Foxo1 Igf1 Insrr Igf1r Irs1 Irs2 HISTAMINE H2 RECEPTOR MEDIATED SIGNALING PATHWAY%PANTHER PATHWAY%P04386 Histamine H2 receptor mediated signaling pathway Adcy2 Adcy7 Prkar2a Gng3 Prkar2b Gng5 Prkaca Gng7 Gng8 Gngt2 Gnb2 Gnb1 Gnb4 Gnal Gnb3 Gnb5 Prkx Hrh2 Prkacb Gng10 BETA3 ADRENERGIC RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P04379 Beta3 adrenergic receptor signaling pathway Adcy2 Adcy7 Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb1 Gnb4 Gnal Gnb3 Gnb5 Adrb3 Gng10 PURINE METABOLISM%PANTHER PATHWAY%P02769 Purine metabolism Ampd3 Gda Xdh Nt5e METHIONINE BIOSYNTHESIS%PANTHER PATHWAY%P02753 Methionine biosynthesis Mtr CORTOCOTROPIN RELEASING FACTOR RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P04380 Cortocotropin releasing factor receptor signaling pathway Gng3 Pomc Gng5 Gng7 Gnaq Gng8 Gngt2 Gnb2 Gnb1 Gnb4 Gnal Gnb3 Gnb5 Crh Crhr2 Gna11 Crhr1 Gng10 Gna14 ALZHEIMER DISEASE-AMYLOID SECRETASE PATHWAY%PANTHER PATHWAY%P00003 Alzheimer disease-amyloid secretase pathway Klc1 Adam17 Mapk4 Klc4 Klc3 Klc2 Mapk15 Apba1 Prkcz Apba2 Cacnb2 Apba3 Pkn1 Mapk12 Mapk13 App Mapk14 Cacna1c Kat5 Mapk9 Mapk8 Mapk11 Mapk1 Mapk6 Bace2 Bace1 Mapk3 Psenen Pkn2 Psen1 Psen2 Cacnb1 Prkcq Prkcg Prkch Ncstn Prkci Aph1b Prkcb Prkcd Prkce Prkca Cacna1f Cacna1d Mapk10 CYSTEINE BIOSYNTHESIS%PANTHER PATHWAY%P02737 Cysteine biosynthesis Cbs AXON GUIDANCE MEDIATED BY SLIT ROBO%PANTHER PATHWAY%P00008 Axon guidance mediated by Slit Robo Dcc Srgap1 Ntng1 Rac2 Cxcl12 Rac1 Slit1 Slit2 Slit3 Robo1 Cxcr4 Abl1 Ntn1 Ntn3 DE NOVO PYRIMIDINE RIBONUCLEOTIDES BIOSYTHESIS%PANTHER PATHWAY%P02740 De novo pyrimidine ribonucleotides biosythesis Dscaml1 Nme3 Dhodh Nme2 Cad Ctps2 Cps1 Ctps1 Nme1 EGF RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P00018 EGF receptor signaling pathway Shc2 Pik3cg Prkcz Pik3cb Pik3cd Pik3c2b Pik3c2a Map2k7 Map2k2 Map2k1 Erbb4 Hras Stat6 Stat4 Akt3 Akt2 Rras Sos1 Pik3r5 Shc1 Stat5a Shc3 Stat5b Rasa2 Stat3 Rasa1 Map2k6 Stat2 Map3k4 Stat1 Mapk12 Mapk13 Grap Mapk14 Map2k4 Erbb2 Erbb3 Mapk9 Mras Rasal2 Gab1 Mapk8 Gab2 Egfr Mapk11 Phldb2 Prkd3 Nf1 Mapk1 Rras2 Dab2ip Map2k3 Prkd1 Spry2 Braf Spry1 Prkd2 Spry4 Pik3c3 Mapk3 Rac2 Akt1 Rac1 Plcg1 Araf Prkcq Plcg2 Prkcg Prkch Map3k3 Prkci Map3k2 Nras Prkcb Prkcd Prkce Prkca Raf1 Mapk10 PLASMINOGEN ACTIVATING CASCADE%PANTHER PATHWAY%P00050 Plasminogen activating cascade Serpinb2 Fgb Fga Mmp13 Mmp1 Plau Fgg Serpinf2 Plat Plg Serpine1 Mmp9 PNAT%PANTHER PATHWAY%P05912 PNAT Stx3 Gng3 Gng8 Gnb2 Vamp8 Gnb4 Vamp1 Gnb3 Vamp3 Vamp2 Snap29 Prkx Prkacb Snap25 Snap23 Epb41l2 Clic6 Ppp1r1b Kcnk3 Epb41l1 Slc18a2 Adcy2 Drd2 Adcy7 Drd4 Prkar2a Ppp1ca Prkar2b Prkaca Kcnk9 Gnai2 Epb41 Slc6a3 Gng11 Gnai3 Gnb1 Flna Gnai1 Epb41l3 Drd1 Drd5 Ppp1cc Gnaz HEDGEHOG SIGNALING PATHWAY%PANTHER PATHWAY%P00025 Hedgehog signaling pathway Shh Smo Ptch1 Sufu Crebbp Stk36 Fbxw11 Gli1 Btrc MUSCARINIC ACETYLCHOLINE RECEPTOR 2 AND 4 SIGNALING PATHWAY%PANTHER PATHWAY%P00043 Muscarinic acetylcholine receptor 2 and 4 signaling pathway Kcnj5 Chrm2 Chrm4 Gnat2 Gnat1 Gng3 Gng5 Gng7 Gng8 Gngt2 Slc5a7 Gnb2 Gnb4 Gnb3 Gnb5 Adcy10 Prkar1b Prkx Prkacb Gnao1 Prkar2a Prkar2b Prkaca Gnai2 Gng11 Gnai3 Gnb1 Gnai1 Slc18a3 Slc6a8 Kcnj3 Gng10 Kcnj9 Kcnj6 N-ACETYLGLUCOSAMINE METABOLISM%PANTHER PATHWAY%P02756 N-acetylglucosamine metabolism Amdhd2 Gnpda2 Npl Gfpt1 Gfpt2 TGF-BETA SIGNALING PATHWAY%PANTHER PATHWAY%P00052 TGF-beta signaling pathway Bmp10 Bmp8a Bmp15 Dcp1b Lefty2 Acvr1 Foxh1 Smurf1 Jund Acvr1c Snip1 Hras Lefty1 Tgfb2 Tgfb3 Gdnf Skil Cited1 Acvrl1 Cited2 Acvr1b Crebbp Amhr2 Fosl1 Mstn Gdf2 Bmpr1a Gdf3 Gdf6 Bmp7 Bmp6 Bmp5 Gdf7 Bmp4 Rras Bmpr2 Smad1 Bmp3 Smad2 Gdf9 Nodal Bmp2 Smad3 Smad4 Bmp1 Smad9 Acvr2a Tll2 Gdf15 Inhba Inhbb Acvr2b Junb Inhbc Tgfbr1 Smad5 Tgfbr2 Smad6 Inhbe Smad7 Gdf11 Gdf10 Map3k7 Mapk12 Mapk13 Mapk14 Mapk9 Jun Mapk8 Mapk11 Mapk1 Mapk3 Atf2 Nras Mapk10 BLOOD COAGULATION%PANTHER PATHWAY%P00011 Blood coagulation F2r Kng2l1 Klkb1 Gp5 Proc Gp9 Gp1bb F13b Gp1ba Procr Vwf F10 F12 Proz Tfpi F2 Serpina10 F3 Thbd F7 F8 F9 Pros1 Fgb Itga2b Fga Plau Fgg Plat Plg PI3 KINASE PATHWAY%PANTHER PATHWAY%P00048 PI3 kinase pathway Gnat2 Rps6kb1 Pik3cb Gnaq Casp9 Gngt2 Nos3 Gnb2 Gnb4 Gnb3 Gnb5 Insr Irs1 Ptger1 Foxo4 Gngt1 Ywhaz Pdpk1 Akt3 Akt2 Foxo3 Gnai2 Akt1 Gnai3 Gsk3b Gnb1 Gnai1 Nras Sos1 Foxo1 Pik3r5 Gna11 Pik3r1 Pik3r2 Gna14 Pik3r3 HETEROTRIMERIC G-PROTEIN SIGNALING PATHWAY-GI ALPHA AND GS ALPHA MEDIATED PATHWAY%PANTHER PATHWAY%P00026 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway Kcnj5 Chrm2 Chrm4 Rap1a Rap1b Gsk3b Gngt1 Adora2b Adora2a Adra2c Adra2b Htr6 Htr7 Gsk3a Oprl1 Adcy2 Phka1 Drd2 Phka2 Drd4 Adrb2 Adra1b Prkaca Adra1a Adra1d Sstr5 Sstr4 Sstr3 Sstr2 Sstr1 Gnb1 Oprm1 Htr5a Gnai1 Phkb Chrm1 Chrm3 Chrm5 Hrh4 Hrh3 Adora1 Gnrhr Gys1 Gys2 Clta Cltb Cltc Mtnr1a Creb1 Creb3 Phkg1 Phkg2 Mtnr1b Pygb Pygl Grm2 Gpr50 Oprk1 Crebbp Creb3l3 Creb3l4 Creb3l1 Creb3l2 Adrb1 Hrh2 Adrb3 Creb5 Gng10 Oprd1 Hrh1 Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Adcy3 Prkar1b Prkacb Grm1 Grm5 Htr2a Htr2c Htr2b Adcy7 Prkar2a Prkar2b Htr1d Grm4 Htr1f Grm7 Gnai2 Grm6 Htr1b Grm8 Htr1a Gnai3 Htr4 Gnal Drd1 Drd5 Adcy4 Adcy8 Adcy5 Adcy6 Kcnj3 Kcnj9 Kcnj6 FGF SIGNALING PATHWAY%PANTHER PATHWAY%P00021 FGF signaling pathway Pik3cg Prkcz Map3k6 Pik3cb Frs2 Pik3cd Frs3 Fgfr3 Pik3c2b Fgfr4 Pik3c2a Fgfr1 Fgfr2 Map2k7 Map2k2 Map2k1 Hras Akt3 Akt2 Sos1 Shc1 Shc3 Rasa2 Rasa1 Map2k6 Map3k4 Mapk12 Mapk13 Grap Mapk14 Map2k4 Mapk9 Mapk8 Mapk11 Mapk1 Map2k3 Spry2 Spry1 Spry4 Pik3c3 Mapk3 Rac2 Akt1 Rac1 Plcg1 Araf Prkcq Plcg2 Prkcg Prkch Map3k3 Prkci Map3k2 Nras Prkcb Prkcd Ptpn6 Prkce Prkca Raf1 Mapk10 ARGININE BIOSYNTHESIS%PANTHER PATHWAY%P02728 Arginine biosynthesis Ass1 Otc Cad Cps1 Asl HETEROTRIMERIC G-PROTEIN SIGNALING PATHWAY-ROD OUTER SEGMENT PHOTOTRANSDUCTION%PANTHER PATHWAY%P00028 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction Gnat1 Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb4 Gnb5 Cnga3 Pdc Cnga1 Grk1 Rho Calml3 Rgs9 Cngb1 Pde6a Gngt1 Pde6b Cngb3 Rcvrn Gng13 Gnb1 Gng10 ALANINE BIOSYNTHESIS%PANTHER PATHWAY%P02724 Alanine biosynthesis Bcat1 Bcat2 PARKINSON DISEASE%PANTHER PATHWAY%P00049 Parkinson disease Mapk15 Elk1 Mapk12 Mapk14 Mapk9 Ywhaz Mapk8 Psma4 Psma3 Mapk1 Psma6 Psma5 Ccne2 Psma2 Psma1 Ccne1 Cask Ywhah Mapk3 Ywhag Ywhae Pld2 Th Ywhab Psmb10 Slc6a3 Sncaip Psmb7 Prkn Psmb1 Gpr37l1 Septin5 Psmb3 Stx7 Septin2 Septin1 Gpr37 Stx12 Ndufv2 Sfn Snca Mapk10 MUSCARINIC ACETYLCHOLINE RECEPTOR 1 AND 3 SIGNALING PATHWAY%PANTHER PATHWAY%P00042 Muscarinic acetylcholine receptor 1 and 3 signaling pathway Grin2a Gng3 Gng5 Prkcz Gng7 Gnaq Pkn1 Gng8 Grin1 Gngt2 Slc5a7 Gnb2 Gnb4 Gnb3 Gnb5 Itpr3 Itpr2 Itpr1 Grin2d Grin2c Grin2b Pkn2 Gng11 Gnb1 Prkcq Prkcg Chrm1 Prkch Chrm3 Prkci Slc18a3 Prkcb Prkcd Prkce Plcb4 Prkca Gna11 Gng10 Gna14 OPIOID PROENKEPHALIN PATHWAY%PANTHER PATHWAY%P05915 Opioid proenkephalin pathway Adcy2 Oprd1 Adcy7 Gng3 Gng5 Gng7 Gnai2 Gng8 Gngt2 Gnai3 Gnb2 Gnb1 Gnb4 Gnai1 Gnb3 Gnb5 Pdyn Penk Gng10 DNA REPLICATION%PANTHER PATHWAY%P00017 DNA replication Rfc3 Rfc4 Pcna Rfc1 H3f3b Rfc2 Rpa2 Top1 Dna2 Rfc5 Pold2 Pold1 METHYLMALONYL PATHWAY%PANTHER PATHWAY%P02755 Methylmalonyl pathway Pccb DE NOVO PURINE BIOSYNTHESIS%PANTHER PATHWAY%P02738 De novo purine biosynthesis Nme3 Nme2 Adsl Rrm2 Impdh2 Rrm2b Gmps Ak3 Ak2 Ak4 Adss2 Dscaml1 Atic Nme7 Ppat Nme6 Guk1 Gart Nme1 VITAMIN D METABOLISM AND PATHWAY%PANTHER PATHWAY%P04396 Vitamin D metabolism and pathway Rxra Vdr F13b Rara Gc HETEROTRIMERIC G-PROTEIN SIGNALING PATHWAY-GQ ALPHA AND GO ALPHA MEDIATED PATHWAY%PANTHER PATHWAY%P00027 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway Chrm2 Chrm4 Grm2 Prkcz Oprk1 Rhoa Rap1a Gng13 Rap1b Dnajc27 Plcb4 Plcb3 Gna11 Gng10 Gna14 Plcb2 Plcb1 Oprd1 Gng3 Gng5 Gng7 Gnaq Gng8 Gngt2 Gnb2 Gnb4 Gnb3 Itpr3 Itpr2 Itpr1 Grm1 Grm5 Gngt1 Rap1gap Adora2b Rasgrp3 Adora2a Rasgrp4 Rasgrp1 Rasgrp2 Arhgef1 Bdkrb2 Oprl1 Gnao1 Bdkrb1 Gpr45 Drd2 Drd4 Cacna1e Grm4 Grm7 Grm6 Sstr5 Grm8 Sstr4 Sstr3 Sstr2 Sstr1 Gnb1 Prkcq Oprm1 Cacna1a Prkcg Cacna1b Prkch Chrm1 Drd1 Prkci Chrm3 Drd5 Chrm5 Prkcb Adora1 Gnrhr Prkcd Prkce Clta Prkca Cltb Cltc ANGIOGENESIS%PANTHER PATHWAY%P00005 Angiogenesis Lpxn Arhgap8 Shc2 Map3k1 Pxn Hif1a Vegfa Pik3cg Prkcz Pik3cb Pik3cd Casp9 Nos3 Pik3c2b Pik3c2a Ptk2 Map2k2 Tgfb1i1 Map2k1 Hras Rhoa Rhob Wnt5a Wnt5b Akt3 Wnt10b Akt2 Pld1 Pld2 Notch1 Fos Notch2 Crk Gsk3b Src Sos1 Shc1 Rbpjl Wnt7b Dvl1 Dvl3 Wnt7a F2r Wnt2 Wnt1 Tcf7l2 Stat3 Rasa1 Fzd1 Pdgfrb Stat1 Pdgfra Pdgfa Fzd2 Pdgfb Fzd5 Grap Nck2 Jak1 Nck1 Frs2 Frs3 Fgfr1 Ctnnb1 Pak1 Pak3 Pak2 Hspb1 Mapkapk3 Mapk14 Mapkapk2 Map2k4 Jun Mapk8 Prr5 Prkd3 Mapk1 Crkl Pla2g4a Prkd1 Braf Prkd2 Grb14 Ets1 Fgf1 Pik3c3 Mapk3 Dok1 Dok3 Cryab Axin1 Akt1 Grb7 Pdgfc Sh2d2a Tcf7 Plcg1 Efnb1 Araf Jag2 Prkcq Efnb2 Plcg2 Jag1 Prkcg Pla2g4d Prkch Angpt1 Prkci Apc2 Nras Epha3 Prkcb Ephb1 Sphk2 Ephb2 Arhgap1 Dll1 Prkcd Ephb3 Sphk1 Dll3 Prkce Dll4 Prkca Dlk1 Raf1 Apc Pik3r1 Pik3r2 Pik3r3 DE NOVO PYRIMIDINE DEOXYRIBONUCLEOTIDE BIOSYNTHESIS%PANTHER PATHWAY%P02739 De novo pyrimidine deoxyribonucleotide biosynthesis Dscaml1 Nme3 Nme2 Nme1 Rrm2 Tyms Rrm2b SYNAPTIC_VESICLE_TRAFFICKING%PANTHER PATHWAY%P05734 Synaptic_vesicle_trafficking Syt1 Syt11 Syt12 Syt7 Syt6 Unc13c Rab3a Stxbp1 Unc13b Syt15 Stx2 Unc13d Stx1b Vamp1 Stx1a Snap25 Syt5 Syt3 Syt2 GASTRIN_CCK2R_240212%PANTHER PATHWAY%P06959 Gastrin_CCK2R_240212 Pxn Pik3cb Nr2c2 Clu Ier3 Ptk2 Rps6 Map2k2 Sp1 Sp3 Map2k1 Elavl1 Akt1s1 Itgav Yes1 Snai1 Tcf4 Rhoa Hbegf Nos1 Irs1 Hdac7 Casp3 Akap1 Cckbr Cdh1 Pparg Gucy2e Arhgef28 Bax Cd38 Ptgs2 Camk4 Elk4 Map2k5 Pdpk1 Ptpn11 Map3k14 Itgb1 Tpcn1 Bad Cck Gast Foxo3 Map3k11 Fos Crk Gsk3b Arrb2 Rps6ka3 Egr1 Src Rps6ka1 Bcar1 Sos1 Shc1 Ptk2b Stat3 Jak2 Slc18a2 Prkaca Gnb1 Lyn Ppp3ca Nfkbia Grb2 Creb1 Mapk10 Eif4ebp1 Rps6kb1 Nfatc2 Odc1 Ctnnb1 Ywhab Foxo1 Pak1 Traf6 Srf Mef2d Elk1 Map2k6 Hspb1 Mapk14 Rock1 Itpr1 Eif4e Map2k4 Prkacb Mef2c Mapk9 Jun Mapk8 Mapk1 Pla2g4a Prkd1 Bcl2 Braf Prkd2 Mapk3 Plau Akt1 Rac1 Plcg1 Araf Prkcq Atf2 Prkch Prkcb Prkcd Prkce Prkca Raf1 Pik3r1 Bcl2l1 GLYCOLYSIS%PANTHER PATHWAY%P00024 Glycolysis Aldoa Pklr Eno1 Bpgm Eno2 Pfkl Pkm Pgk1 Pgam2 Tpi1l2 Pfkm Gpi Hk2 NOTCH SIGNALING PATHWAY%PANTHER PATHWAY%P00045 Notch signaling pathway Jag1 Maml1 Numb Cirsr Dll3 Dll4 Notch1 Notch2 Dlk1 Rbpjl Notch3 Jag2 GAMMA-AMINOBUTYRIC ACID SYNTHESIS%PANTHER PATHWAY%P04384 Gamma-aminobutyric acid synthesis Csad Gad1 Gad2 Abat FAS SIGNALING PATHWAY%PANTHER PATHWAY%P00020 FAS signaling pathway Gsn Casp6 Capg Scin Apaf1 Dffb Fadd Casp9 Map2k4 Casp8 Casp7 Casp3 Mapk9 Jun Mapk8 Fas Faslg Daxx Faf1 Parp3 Parp2 Parp1 Cflar Lmnb1 Lmnb2 Mapk10 INFLAMMATION MEDIATED BY CHEMOKINE AND CYTOKINE SIGNALING PATHWAY%PANTHER PATHWAY%P00031 Inflammation mediated by chemokine and cytokine signaling pathway Rela Arpc3 Pik3cg Arpc2 Prkcz Pik3cb Pik3cd Arpc5 Jund Col12a1 Ikbkb Cxcr1 Rhoa Cxcr2 Itgal Pdpk1 Itgb7 Akt3 Itgb1 Acta1 Akt2 Actb Rras Sos1 Shc1 Junb Il2 Col6a2 Ptk2b Cxcr3 Cxcr5 Cxcl10 Actg1 Fpr1 Actg2 Fpr3 Ccr10 Stat3 Ccr1 Xcr1 Vwf Actbl2 Ccrl2 Actc1 Chuk Ltb4r2 Rhog Ccr9 Grap Ccr8 Ccr7 Ccr6 Ccr5 Ccr4 Ccr3 Jak2 Ccr2 Cx3cr1 Ifnar1 Camk2d Ccl11 Ccl12 Ccl7 Camk2a Ccl5 Ccl4 Ccl3 Ccl2 Adcy2 Pf4 Prex1 Cx3cl1 Nfat5 Prkaca Ccl22 Ccl20 Ccl21 Gnai1 Myo3b Vav1 Myh2 Myh3 Myh4 Myh7 Myh11 Myh10 Myh7b Nfatc4 Nfatc3 Nfatc2 Cask Kras Plcb4 Mylk2 Plcb3 Gna11 Mylk3 Gng10 Gna14 Plcd1 Plcb2 Plcd4 Pak1 Plcb1 Pak6 Gng3 Pak3 Gng5 Pak2 Plcl1 Pak5 Gng7 Pak4 Gnaq Gng8 Plcz1 Mylk Plce1 Arpc4 Cxcr4 Gnb3 Rock1 Itpr3 Itpr2 Itpr1 Prkx Prkacb Ifng Jun Col14a1 Mapk1 Gnao1 Mapk3 Arpc1b Rac2 Gnai2 Akt1 Arpc1a Rac1 Plcg1 Gnai3 Araf Plcg2 Nras Prkcb Adcy5 Adcy6 Prkce Nfkb2 Raf1 XANTHINE AND GUANINE SALVAGE PATHWAY%PANTHER PATHWAY%P02788 Xanthine and guanine salvage pathway Gda Prtfdc1 Pnp Hprt1 HUNTINGTON DISEASE%PANTHER PATHWAY%P00029 Huntington disease Dync1li1 Dnai2 Dynll1 Grin2a Dynll2 Apaf1 Capn9 Cyc1 Capn5 Capn7 Capn6 Capn1 Grin1 Capn3 Arpc5 Capn2 Dlg4 Dnah5 Dnah8 Map2k7 Cyfip1 Sp1 Capns1 Capn11 Capn12 Casp8 Grik5 Casp3 Crebbp Grik2 Grik1 Grik4 Grik3 Grin2d Grin2c Grin2b Acta1 Actb Actr2 Tp53 Fos Tp73 Tbp Tp63 Tubb2b Tubb2a Actg1 Actg2 Tubb5 Tubb6 Tubb3 Actbl2 Actc1 Rhog Tubb4b Map2k4 Mapk9 Map3k10 Jun Rac2 Arpc1b Rac1 Arpc1a Hip1 Bdnf Ift57 Dync1h1 Dnal4 Dctn1 Rhoj Rhoq Dync1i2 Dync1i1 Ap2a2 Ap2a1 Hap1 Hip1r Kalrn Cltb Htt Gapdhs Dync1li2 Dync2h1 ALLANTOIN DEGRADATION%PANTHER PATHWAY%P02725 Allantoin degradation Allc PYRUVATE METABOLISM%PANTHER PATHWAY%P02772 Pyruvate metabolism Acly Pc Me1 Clybl Pck1 Pklr Cs Pdha2 Pkm T CELL ACTIVATION%PANTHER PATHWAY%P00053 T cell activation Map3k1 Pik3cg Pik3cb Pik3cd Map2k2 Map2k1 Hras Ikbkb Zap70 Cd28 Cd86 Cd80 Lck Lcp2 Cd3g Cd247 Cd3d Ppp3cc Lat Akt3 Akt2 Fos Sos1 Pak1 Pak3 Pak2 Chuk Itpr1 Nck2 Nck1 Mapk9 Jun Mapk8 Mapk1 Braf Pik3c3 Mapk3 Grap2 Akt1 Rac1 Plcg1 Araf Vav3 Prkcq Vav1 Vav2 Nras Ptprc Ppp3ca Raf1 Ppp3cb Pik3r1 Nfkbia Pik3r2 Pik3r3 TOLL RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P00054 Toll receptor signaling pathway Traf6 Elk1 Map3k7 Chuk Map2k2 Mapk14 Map2k1 Ikbkb Mapk9 Jun Mapk8 Map2k3 Map3k8 Tbk1 Ticam2 Mapk3 Irak4 Ecsit Nfkbie Tollip Irak1 Tlr10 Myd88 Tank Irf3 Tlr7 Tlr6 Tirap Tlr4 Tlr3 Tlr2 Nfkbia VITAMIN B6 METABOLISM%PANTHER PATHWAY%P02787 Vitamin B6 metabolism Psat1 WNT SIGNALING PATHWAY%PANTHER PATHWAY%P00057 Wnt signaling pathway Wnt5a Cdh1 Wnt5b Wnt9a Wnt9b Wnt10b Arrb2 Wnt8a Arrb1 Fstl1 Lef1 Wnt11 Lrp6 Hdac1 Lrp5 Wnt6 Wnt7b Wnt3a Dvl1 Dvl3 Wnt7a Wnt2 Tcf7l1 Wnt1 Wnt4 Wnt3 Tcf7l2 Fzd1 Fzd2 Fzd5 Fzd4 Pcdhb2 Fzd6 Pcdhb1 Fzd9 Fzd8 Cdh9 Cdh8 Cdh7 Cdh6 Cdh5 Pcdhgb7 Pcdh10 Cdh2 Pcdh19 Pcdh18 Pcdh15 Pcdha1 Pcdhga11 Pcdhga10 Pcdhga12 Pcdha7 Pcdha6 Pcdha8 Pcdha3 Pcdha2 Pcdha5 Pcdha4 Pcdhgc3 Cdh24 Cdh23 Cdh20 Celsr3 Celsr1 Pcdhb10 Celsr2 Pcdh20 Fat2 Fat1 Fat3 Pcdhb22 Pcdhac2 Cdhr2 Ppp3ca Pcdha13 Ppp3cb Cdhr1 Pcdha10 Pcdha11 Pcdh1 Cdh19 Cdh18 Cdh17 Pcdh11x Cdh16 Cdh15 Cdh13 Cdh12 Cdh11 Cdh10 Pcdh8 Pcdh7 Pcdh9 Pcdhga5 Pcdhga7 Pcdhga8 Pcdhga1 Pcdhga2 Pcdhga3 Crebbp Ppp3cc Arr3 Smarce1 Srcap Tbl1x Nlk Kremen2 Kremen1 Siah2 Ino80 Ep400 Hells Hltf Csnk1a1 Ppp2r5d Smarcal1 Ppp2r5c Ppp2r5b Ppp2r5a Ankrd6 Ppp2r5e Chd1l Arid1a Pygo2 Pygo1 Tle4 Tle3 Tle2 Tle1 Ctnna2 Ctnna1 Csnk1g3 Hdac3 Hdac2 Csnk1g2 Tbl1xr1 Smarcb1 Hdac8 Csnk2b Smarca2 Sag Smarca1 Smarca4 Ctnnal1 Ppp3r2 Ppp3r1 Dact1 Smarcd3 Smarcd2 Smarcc2 Smarcc1 Prkcq Prkcg Prkch Prkci Prkcb Prkcd Prkce Prkca Fbxw11 Btrc Prkcz Smad1 Gsk3b Smad4 Smad5 Gnb1 Csnk1d Csnk1e Nfatc4 Nfatc3 Gng13 Nfatc2 Ctnnb1 Ppp2cb Ppp2ca Siah1 Plcb4 Plcb3 Gna11 Gng10 Gna14 Plcb2 Plcb1 Gng3 Gng5 Gng7 Gnaq Gng8 Gnb2 Gnb4 Gnb3 Itpr3 Itpr2 Itpr1 Axin1 ADENINE AND HYPOXANTHINE SALVAGE PATHWAY%PANTHER PATHWAY%P02723 Adenine and hypoxanthine salvage pathway Ada Prtfdc1 Xdh Pnp Hprt1 TRIACYLGLYCEROL METABOLISM%PANTHER PATHWAY%P02782 Triacylglycerol metabolism Lipc Lipe METABOTROPIC GLUTAMATE RECEPTOR GROUP II PATHWAY%PANTHER PATHWAY%P00040 Metabotropic glutamate receptor group II pathway Gnat2 Gng3 Grm2 Gng5 Gng7 Gng8 Gngt2 Gnb2 Vamp8 Gnb4 Vamp1 Gnb3 Gnb5 Vamp3 Adcy10 Vamp2 Prkar1b Snap29 Prkx Prkacb Snap25 Snap23 Gnao1 Prkar2a Prkar2b Cacna1e Prkaca Gnai2 Gng11 Gnai3 Stx1b Gnb1 Cacnb1 Stx1a Gnai1 Cacna1a Cacna1b Gng10 UNTITLED%PANTHER PATHWAY%P05916 untitled Gnao1 Adcy2 Adcy7 Gng3 Gng5 Oprk1 Gng7 Gnai2 Gng8 Avp Gngt2 Oxt Gnai3 Gnb2 Gnb1 Gnb4 Gnai1 Gnb3 Gnb5 Pdyn Gng10 AXON GUIDANCE MEDIATED BY SEMAPHORINS%PANTHER PATHWAY%P00007 Axon guidance mediated by semaphorins Arhgef1 Pak1 Rac2 Dpysl2 Nrp1 Rac1 Dpysl4 Plxnb1 Dpysl5 Sema3a Sema4d Cdk5 Dpys Fes Crmp1 Frk Rhoa Fyn ENDOGENOUS_CANNABINOID_SIGNALING%PANTHER PATHWAY%P05730 Endogenous_cannabinoid_signaling Plcb2 Gnao1 Plcb1 Gng3 Gng5 Gng7 Gng8 Gngt2 Gng11 Gnai3 Gnb2 Gnb1 Gnb4 Gnai1 Gnb3 Cacna1a Cacna1b Cnr1 Cacna1g Grm1 Grm5 Plcb3 GENERAL TRANSCRIPTION BY RNA POLYMERASE I%PANTHER PATHWAY%P00022 General transcription by RNA polymerase I Taf1c Rrn3 Tbp Polr1b Taf1a Tbpl2 Cavin1 Tbpl1 Taf1b Ubtf Taf8 Psmc3ip PYRIDOXAL PHOSPHATE SALVAGE PATHWAY%PANTHER PATHWAY%P02770 Pyridoxal phosphate salvage pathway SALVAGE PYRIMIDINE DEOXYRIBONUCLEOTIDES%PANTHER PATHWAY%P02774 Salvage pyrimidine deoxyribonucleotides Cda BETA2 ADRENERGIC RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P04378 Beta2 adrenergic receptor signaling pathway Adcy2 Adcy7 Prkar2a Gng3 Prkar2b Gng5 Adrb2 Prkaca Gng7 Gng8 Gngt2 Gnb2 Gnb1 Gnb4 Gnal Gnb3 Gnb5 Prkx Prkacb Gng10 ENKEPHALIN RELEASE%PANTHER PATHWAY%P05913 Enkephalin release Oprd1 Gng3 Gng5 Gng7 Gng8 Gngt2 Gnb2 Gnb4 Gnb3 Gnb5 Prkx Prkacb Gnao1 Adcy2 Adcy7 Prkar2a Prkar2b Prkaca Gnai2 Gnai3 Gnb1 Oprm1 Gnal Gnai1 Pdyn Penk Gng10 Creb1 ASPARAGINE AND ASPARTATE BIOSYNTHESIS%PANTHER PATHWAY%P02730 Asparagine and aspartate biosynthesis Asns ALPHA ADRENERGIC RECEPTOR SIGNALING PATHWAY%PANTHER PATHWAY%P00002 Alpha adrenergic receptor signaling pathway Adra2b Plcb2 Plcb1 Adra1b Adra1a Plce1 Prkcg Itpr1 Prkcd Prkce Plcb4 Prkca Plcb3 Gna11 Adra2c