LOVASTATIN ACTION PATHWAY%SMPDB%SMP0000099 Lovastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 KANAMYCIN ACTION PATHWAY%SMPDB%SMP0000255 Kanamycin Action Pathway SEGAWA SYNDROME%PATHWHIZ%PW000466 Segawa Syndrome 110391 20751 13361 11677 12408 19286 320415 14528 TEMOCAPRIL ACTION PATHWAY%PATHWHIZ%PW000710 Temocapril Action Pathway 100038824 11606 11421 ALPRENOLOL ACTION PATHWAY%SMPDB%SMP0000297 Alprenolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 VATALANIB ACTION PATHWAY%SMPDB%SMP0000421 Vatalanib Action Pathway 16542 THE ONCOGENIC ACTION OF FUMARATE%PATHWHIZ%PW002363 The Oncogenic Action of Fumarate 55951 269951 112407 112406 66945 18563 67834 27376 56451 66925 209692 20917 11429 13382 14194 235339 68263 15926 170718 11428 18597 15929 78920 67680 66052 12974 ISRADIPINE ACTION PATHWAY%PATHWHIZ%PW000393 Isradipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 METHYLMALONIC ACIDURIA DUE TO COBALAMIN-RELATED DISORDERS%PATHWHIZ%PW000208 Methylmalonic Aciduria Due to Cobalamin-Related Disorders 13382 110446 12039 68738 268860 12040 93747 227095 66904 110821 11364 13171 104776 56690 106557 107476 73724 ION CHANNEL AND PHORBAL ESTERS SIGNALING PATHWAY%SMPDB%SMP0120969 Ion Channel and Phorbal Esters Signaling Pathway 19229 18750 18803 18751 18442 THIOGUANINE METABOLISM PATHWAY%PATHWHIZ%PW000623 Thioguanine Metabolism Pathway 15452 PREDNISOLONE ACTION PATHWAY%SMPDB%SMP0000441 Prednisolone Action Pathway 14815 15519 CONGENITAL DISORDER OF GLYCOSYLATION CDG-IID%PATHWHIZ%PW000555 Congenital Disorder of Glycosylation CDG-IId 18103 14430 216558 76025 14377 66588 16770 22232 20525 14595 CD40L SIGNALLING PATHWAY%SMPDB%SMP0089759 CD40L Signalling Pathway 21939 21947 12675 230233 26416 26401 22034 18033 18035 16151 16150 22031 19252 21929 INOSITOL METABOLISM%SMPDB%SMP0087396 Inositol Metabolism 224020 228550 83493 56717 56208 18711 16329 71780 55980 66461 74769 56727 234729 269180 75669 69718 18798 TRANSALDOLASE DEFICIENCY%SMPDB%SMP0120804 Transaldolase Deficiency 14381 18641 19895 71336 21351 21881 11674 19139 14121 14751 CAPTOPRIL ACTION PATHWAY%SMPDB%SMP0000146 Captopril Action Pathway 100038824 11606 11421 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW088271 Starch and Sucrose Metabolism 110006 223337 70974 14936 72157 11722 77559 14387 216558 22235 110095 14751 LEUKOTRIENE C4 SYNTHESIS DEFICIENCY%PATHWHIZ%PW000118 Leukotriene C4 Synthesis Deficiency 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 PYRUVATE DECARBOXYLASE E1 COMPONENT DEFICIENCY (PDHE1 DEFICIENCY)%SMPDB%SMP0000334 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) 17436 76238 18563 13382 235339 68263 18597 110446 17449 11677 60525 14651 109801 52815 11669 18770 18534 16828 107476 66204 74156 CARNITINE PALMITOYL TRANSFERASE DEFICIENCY II%PATHWHIZ%PW000517 Carnitine Palmitoyl Transferase Deficiency II 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 CYSTATHIONINE BETA-SYNTHASE DEFICIENCY%SMPDB%SMP0000177 Cystathionine beta-Synthase Deficiency 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 MEPYRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057583 Mepyramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CYCLOPHOSPHAMIDE ACTION PATHWAY%PATHWHIZ%PW000248 Cyclophosphamide Action Pathway 11670 107141 11668 14863 13114 13088 13087 72303 LORATADINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061144 Loratadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 THE ONCOGENIC ACTION OF D-2-HYDROXYGLUTARATE IN HYDROXYGLUTARIC ACIDURIA%SMPDB%SMP0002359 The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria 55951 217666 98314 216456 269951 66945 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 15926 170718 11428 18597 15929 78920 67680 66052 12974 14661 GLYCOGEN SYNTHETASE DEFICIENCY%PATHWHIZ%PW121872 Glycogen Synthetase Deficiency 110006 22239 15275 14751 T CELL RECEPTOR SIGNALING PATHWAY%SMPDB%SMP0120959 T Cell Receptor Signaling Pathway 18750 18803 18751 20963 19353 16818 14784 16797 20416 26419 14281 110157 13712 15461 16476 26401 18708 26400 18033 14360 18035 26395 12313 19055 19697 26417 320139 19419 54446 22190 12502 12503 19056 12500 PENBUTOLOL ACTION PATHWAY%SMPDB%SMP0000305 Penbutolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 MIRTAZAPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062885 Mirtazapine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 DOXORUBICIN METABOLISM PATHWAY%SMPDB%SMP0000650 Doxorubicin Metabolism Pathway 26357 18984 624814 18671 17250 22436 105349 19765 18104 75406 18127 58810 109857 12780 12408 70840 226646 CHOLESTERYL ESTER STORAGE DISEASE%SMPDB%SMP0000508 Cholesteryl Ester Storage Disease 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 GLYCOGENOSIS, TYPE III. CORI DISEASE, DEBRANCHER GLYCOGENOSIS%PATHWHIZ%PW122097 Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 RUPATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060235 Rupatadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 AMMONIA RECYCLING%PATHWHIZ%PW000009 Ammonia Recycling 27053 11833 104174 14661 15109 13382 216456 227231 231691 66514 434437 14645 TYROSINEMIA, TRANSIENT, OF THE NEWBORN%PATHWHIZ%PW000470 Tyrosinemia, Transient, of the Newborn 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 HOMOCHLORCYCLIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW063751 Homochlorcyclizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CHLORTHALIDONE ACTION PATHWAY%SMPDB%SMP0000122 Chlorthalidone Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES%SMPDB%SMP0063805 Cadmium Induces DNA Synthesis and Proliferation in Macrophages 18750 18795 18751 12289 54652 12292 26413 110157 15461 12288 18033 18035 26395 16438 19697 26417 CARTEOLOL ACTION PATHWAY%PATHWHIZ%PW000634 Carteolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 NATEGLINIDE ACTION PATHWAY%SMPDB%SMP0000453 Nateglinide Action Pathway 20927 16334 12286 20526 56808 12295 ACTIVATION OF PKC THROUGH G PROTEIN-COUPLED RECEPTOR%SMPDB%SMP0108012 Activation of PKC Through G Protein-Coupled Receptor 18750 18795 16438 14682 PHENIRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0056662 Pheniramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 AMINO SUGAR METABOLISM%PATHWHIZ%PW000008 Amino Sugar Metabolism 15275 54342 245847 109785 67311 12764 50798 107652 56174 14583 235504 15211 71884 26384 94181 74091 19703 DOXYLAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059730 Doxylamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PHOSPHATIDYLINOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0000463 Phosphatidylinositol Phosphate Metabolism 18718 224020 103199 18795 16331 13649 56208 52858 18711 18704 225326 13866 18707 18720 228361 234515 234729 75669 18708 19211 64436 104015 PHOSPHOENOLPYRUVATE CARBOXYKINASE DEFICIENCY 1 (PEPCK1)%SMPDB%SMP0120843 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY%PATHWHIZ%PW000494 Glucose-6-phosphate Dehydrogenase Deficiency 21881 11674 66171 14751 14121 75456 14381 18641 19895 72157 71336 21351 66646 110208 232449 SPERMIDINE AND SPERMINE BIOSYNTHESIS%PATHWHIZ%PW000037 Spermidine and Spermine Biosynthesis 671878 18263 232087 20810 108645 ANGIOTENSIN METABOLISM%SMPDB%SMP0000587 Angiotensin Metabolism 100038824 11606 11421 MITOCHONDRIAL COMPLEX II DEFICIENCY%PATHWHIZ%PW000524 Mitochondrial Complex II Deficiency 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 PYRUVALDEHYDE DEGRADATION%SMPDB%SMP0000459 Pyruvaldehyde Degradation 14651 109801 52815 FRUCTOSURIA%PATHWHIZ%PW122105 Fructosuria 21991 11674 14121 18641 20322 16548 11677 218138 69080 67883 29858 18639 110119 ADENYLOSUCCINATE LYASE DEFICIENCY%SMPDB%SMP0000167 Adenylosuccinate Lyase Deficiency 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 TOLMETIN ACTION PATHWAY%PATHWHIZ%PW000681 Tolmetin Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 GEMCITABINE ACTION PATHWAY%SMPDB%SMP0000446 Gemcitabine Action Pathway 63959 434203 13178 18102 50773 320685 66588 20135 20133 382985 22171 51797 114304 PHENYTOIN (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000380 Phenytoin (Antiarrhythmic) Action Pathway 20648 11931 11932 243764 11933 11938 13077 58226 394433 11928 71853 18747 69191 16521 12846 67838 98660 394434 16535 12304 12291 394436 16493 19035 330953 64136 16523 12282 20927 67397 16514 14828 20271 22004 13849 16519 94284 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 107141 13114 18104 13383 16511 20191 20928 246133 13106 232975 19084 20649 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW121883 Triosephosphate Isomerase Deficiency 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 LACTOSE SYNTHESIS%SMPDB%SMP0000444 Lactose Synthesis 18103 14430 216558 76025 14377 66588 16770 22232 20525 14595 PYRIMIDINE METABOLISM%PATHWHIZ%PW000160 Pyrimidine Metabolism 110074 69719 54369 320685 76952 76025 14544 68556 20135 76654 72269 22169 56248 72962 21877 16434 382985 64705 22171 99586 51797 103149 56749 SHORT-CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE DEFICIENCY (SCHAD)%PATHWHIZ%PW000544 Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (SCHAD) 110446 15107 11409 15108 52538 93747 11363 TAMOXIFEN METABOLISM PATHWAY%PATHWHIZ%PW000582 Tamoxifen Metabolism Pathway 20887 13982 14262 13114 14261 394433 13088 56448 394434 PROTEIN SYNTHESIS: GLUTAMINE%SMPDB%SMP0111862 Protein Synthesis: Glutamine 20115 319195 67248 100043391 97541 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 VINCRISTINE ACTION PATHWAY%SMPDB%SMP0000437 Vincristine Action Pathway 224814 76408 12575 12780 18671 17250 545486 19765 22143 22059 PHENYLBUTAZONE ACTION PATHWAY%PATHWHIZ%PW000678 Phenylbutazone Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 VITAMIN A DEFICIENCY%SMPDB%SMP0000336 Vitamin A Deficiency 11668 13114 13087 13088 71853 69191 67838 12304 394436 19035 64136 12282 67397 14828 28200 67442 63857 235033 241452 13350 20148 79235 19378 622127 13113 77974 216454 17252 19892 245533 13082 BAMIPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062882 Bamipine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 HYPERPROLINEMIA TYPE I%SMPDB%SMP0000361 Hyperprolinemia Type I 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 OXYTETRACYCLINE ACTION PATHWAY%PATHWHIZ%PW000361 Oxytetracycline Action Pathway ALFENTANIL ACTION PATHWAY%PATHWHIZ%PW000419 Alfentanil Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 REFSUM DISEASE%SMPDB%SMP0000451 Refsum Disease 16922 11671 26874 11666 26458 56794 MEVALONIC ACIDURIA%SMPDB%SMP0000510 Mevalonic Aciduria 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 TOBRAMYCIN ACTION PATHWAY%PATHWHIZ%PW000688 Tobramycin Action Pathway METHIONINE ADENOSYLTRANSFERASE DEFICIENCY%SMPDB%SMP0000221 Methionine Adenosyltransferase Deficiency 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 FOSINOPRIL ACTION PATHWAY%PATHWHIZ%PW000227 Fosinopril Action Pathway 100038824 11606 11421 DIHYDROPYRIMIDINASE DEFICIENCY%SMPDB%SMP0000178 Dihydropyrimidinase Deficiency 110074 69719 54369 320685 76952 76025 14544 68556 20135 76654 72269 22169 56248 72962 21877 16434 382985 64705 22171 99586 51797 103149 56749 DILTIAZEM ACTION PATHWAY%SMPDB%SMP0000359 Diltiazem Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 EUMELANIN BIOSYNTHESIS%SMPDB%SMP0121124 Eumelanin Biosynthesis 22173 13190 PHENYLALANINE AND TYROSINE METABOLISM%PATHWHIZ%PW000042 Phenylalanine and Tyrosine Metabolism 107271 14204 14718 234724 14085 15445 14874 23874 66590 15233 18478 NALTREXONE ACTION PATHWAY%PATHWHIZ%PW000664 Naltrexone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 HYPERLYSINEMIA II OR SACCHAROPINURIA%PATHWHIZ%PW000504 Hyperlysinemia II or Saccharopinuria 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 DIFLUNISAL ACTION PATHWAY%SMPDB%SMP0000289 Diflunisal Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 BENDROFLUMETHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000329 Bendroflumethiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0120583 Glucose-6-phosphate Dehydrogenase Deficiency 230163 14751 18642 19895 67763 71336 14120 100198 21351 66646 110208 232449 83553 FANCONI-BICKEL SYNDROME%PATHWHIZ%PW122116 Fanconi-Bickel Syndrome 18642 15277 21991 14377 100043349 13806 18770 56012 319625 11674 14751 FRUCTOSE INTOLERANCE, HEREDITARY%SMPDB%SMP0120876 Fructose Intolerance, Hereditary 21991 11674 14121 18641 20322 16548 11677 218138 69080 67883 29858 18639 110119 AICA-RIBOSIDURIA%PATHWHIZ%PW000082 AICA-Ribosiduria 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 OMEPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000316 Omeprazole Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 PREDNISONE METABOLISM PATHWAY%PATHWHIZ%PW000607 Prednisone Metabolism Pathway 13114 RISEDRONATE ACTION PATHWAY%PATHWHIZ%PW000272 Risedronate Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 PERINDOPRIL ACTION PATHWAY%SMPDB%SMP0000152 Perindopril Action Pathway 100038824 11606 11421 INTRACELLULAR SIGNALLING THROUGH FSH RECEPTOR AND FOLLICLE STIMULATING HORMONE%PATHWHIZ%PW000448 Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone 14701 14688 14309 12640 210044 18749 19045 12912 14699 AROMATIC L-AMINOACID DECARBOXYLASE DEFICIENCY%PATHWHIZ%PW000090 Aromatic L-Aminoacid Decarboxylase Deficiency 21823 18948 13195 GLYCEROL METABOLISM IV (GLYCEROPHOSPHOGLYCEROL)%SMPDB%SMP0121312 Glycerol Metabolism IV (Glycerophosphoglycerol) PHENYLACETATE METABOLISM%SMPDB%SMP0000126 Phenylacetate Metabolism 117147 107146 PHOSPHOENOLPYRUVATE CARBOXYKINASE DEFICIENCY 1 (PEPCK1)%SMPDB%SMP0000560 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 DEZOCINE ACTION PATHWAY%PATHWHIZ%PW000653 Dezocine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 KIDNEY FUNCTION - DESCENDING LIMB OF THE LOOP OF HENLE%SMPDB%SMP0121009 Kidney Function - Descending Limb of the Loop of Henle 11826 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW002495 Inositol Phosphate Metabolism 55980 CARDIOLIPIN BIOSYNTHESIS (BARTH SYNDROME)%SMPDB%SMP0074684 Cardiolipin Biosynthesis (Barth Syndrome) 110911 66586 52123 66461 14732 74451 14555 GLYCOLYSIS%PATHWHIZ%PW000839 Glycolysis FRUCTOSE-1,6-DIPHOSPHATASE DEFICIENCY%PATHWHIZ%PW122106 Fructose-1,6-diphosphatase Deficiency 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 TRAMADOL METABOLISM PATHWAY%PATHWHIZ%PW000613 Tramadol Metabolism Pathway 20517 12780 13114 13088 56448 394434 GLUCOSE TRANSPORTER DEFECT (SGLT2)%SMPDB%SMP0000184 Glucose Transporter Defect (SGLT2) 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 CIRCADIAN RHYTHMS%SMPDB%SMP0090831 Circadian Rhythms 12753 18160 18626 27373 12952 CREATINE DEFICIENCY, GUANIDINOACETATE METHYLTRANSFERASE DEFICIENCY%PATHWHIZ%PW000480 Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 METIAMIDE ACTION PATHWAY%PATHWHIZ%PW000712 Metiamide Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 APROTININ ACTION PATHWAY%SMPDB%SMP0000288 Aprotinin Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 BCR SIGNALING PATHWAY%SMPDB%SMP0120964 BCR Signaling Pathway 18750 18803 18751 20963 19353 17060 16818 14784 17096 15985 20416 109305 26419 14281 110157 13712 15461 16476 26401 26395 12313 19055 26417 54446 19056 GLYCOGENOSIS, TYPE IB%SMPDB%SMP0000573 Glycogenosis, Type IB 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 ISOTHIPENDYL H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060659 Isothipendyl H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 EMEDASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061990 Emedastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 G-PROTEIN SIGNALING THROUGH TUBBY PROTEINS%PATHWHIZ%PW090863 G-Protein Signaling Through Tubby Proteins 14688 22141 18795 12669 15560 14699 14682 PROTEIN SYNTHESIS: GLUTAMIC ACID%PATHWHIZ%PW112922 Protein Synthesis: Glutamic Acid 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 107508 22121 65019 27050 27370 EPROSARTAN ACTION PATHWAY%PATHWHIZ%PW000279 Eprosartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 PROTEIN SYNTHESIS: PHENYLALANINE%PATHWHIZ%PW112934 Protein Synthesis: Phenylalanine 20115 319195 67248 23874 66590 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 LISINOPRIL ACTION PATHWAY%PATHWHIZ%PW000228 Lisinopril Action Pathway 100038824 11606 11421 GLYCOGENOSIS, TYPE VII. TARUI DISEASE%PATHWHIZ%PW000507 Glycogenosis, Type VII. Tarui Disease 12183 14377 100043349 13806 319625 20526 56012 11674 14751 18648 18642 18655 15277 18770 ACETAMINOPHEN METABOLISM PATHWAY%PATHWHIZ%PW000616 Acetaminophen Metabolism Pathway 13077 13114 13087 71853 69191 67838 394434 12304 394436 19035 64136 12282 67397 14828 94284 20859 14871 27416 239273 231396 20860 20887 26357 56448 18671 17250 13106 PHENYLTOLOXAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059850 Phenyltoloxamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 THREONINE AND 2-OXOBUTANOATE DEGRADATION%SMPDB%SMP0000452 Threonine and 2-Oxobutanoate Degradation 12039 12040 66904 110821 13171 13382 231691 17850 METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY (MTHFRD)%PATHWHIZ%PW000519 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) 107747 14317 13361 17768 100039707 270685 14287 52466 17769 69606 108156 667301 CELECOXIB ACTION PATHWAY%SMPDB%SMP0000096 Celecoxib Action Pathway 71519 14775 208285 17001 19223 13850 13114 100040843 13088 13110 16993 11684 394434 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 56448 12408 72303 14598 13106 72054 66469 CHONDRODYSPLASIA PUNCTATA II, X-LINKED DOMINANT (CDPX2)%SMPDB%SMP0000388 Chondrodysplasia Punctata II, X-Linked Dominant (CDPX2) 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 PROTEIN SYNTHESIS: ALANINE%PATHWHIZ%PW101384 Protein Synthesis: Alanine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 234734 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 METHYLMALONATE SEMIALDEHYDE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000384 Methylmalonate Semialdehyde Dehydrogenase Deficiency 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 GLYCINE AND SERINE METABOLISM%SMPDB%SMP0000004 Glycine and Serine Metabolism 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 FRUCTOSE METABOLISM%PATHWHIZ%PW000913 Fructose Metabolism VINDESINE ACTION PATHWAY%SMPDB%SMP0000438 Vindesine Action Pathway 224814 76408 12575 12780 18671 17250 545486 19765 22143 22059 FEXOFENADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060218 Fexofenadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CIMETIDINE ACTION PATHWAY%SMPDB%SMP0000232 Cimetidine Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 INDOMETHACIN ACTION PATHWAY%PATHWHIZ%PW000260 Indomethacin Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 CLINDAMYCIN ACTION PATHWAY%PATHWHIZ%PW000347 Clindamycin Action Pathway BUCLIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058964 Buclizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 AZATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059865 Azatadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ALKAPTONURIA%PATHWHIZ%PW000180 Alkaptonuria 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 MITOCHONDRIAL ELECTRON TRANSPORT CHAIN%SMPDB%SMP0000355 Mitochondrial Electron Transport Chain 66043 11950 14571 17708 66945 11947 670717 100039108 66925 11949 22273 54405 100043349 11739 14385 17705 11946 67680 66052 VITAMIN K METABOLISM%SMPDB%SMP0000464 Vitamin K Metabolism 56316 18104 27973 LIDOCAINE (LOCAL ANAESTHETIC) METABOLISM PATHWAY%SMPDB%SMP0000620 Lidocaine (Local Anaesthetic) Metabolism Pathway 20266 20264 13077 13114 27-HYDROXYLASE DEFICIENCY%PATHWHIZ%PW000697 27-Hydroxylase Deficiency 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 BIOTIN METABOLISM%SMPDB%SMP0000066 Biotin Metabolism 69019 110948 100705 26363 CARBAMOYL PHOSPHATE SYNTHETASE DEFICIENCY%SMPDB%SMP0000002 Carbamoyl Phosphate Synthetase Deficiency 76282 55963 20514 14719 78830 18408 18416 216456 11846 11898 109900 14661 227231 ISOVALERIC ACIDEMIA%PATHWHIZ%PW000500 Isovaleric Acidemia 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 QUINAPRIL ACTION PATHWAY%SMPDB%SMP0000153 Quinapril Action Pathway 100038824 11606 11421 OXAPROZIN ACTION PATHWAY%PATHWHIZ%PW000262 Oxaprozin Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 GALACTOSE METABOLISM%SMPDB%SMP0000043 Galactose Metabolism 11677 72157 74246 14430 226413 216558 12091 14387 11605 15275 14377 14595 FELBAMATE METABOLISM PATHWAY%SMPDB%SMP0000633 Felbamate Metabolism Pathway 11670 13114 13106 HYDROMORPHONE ACTION PATHWAY%PATHWHIZ%PW000416 Hydromorphone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCEROL METABOLISM III (SN-GLYCERO-3-PHOSPHOETHANOLAMINE)%PATHWHIZ%PW122619 Glycerol Metabolism III (sn-Glycero-3-Phosphoethanolamine) INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW088368 Inositol Phosphate Metabolism 228550 71780 55980 234515 217837 75678 269180 23827 17330 56409 27399 170835 69718 BUTYRATE METABOLISM%PATHWHIZ%PW000014 Butyrate Metabolism 110446 15107 11409 93747 15356 117147 67041 CITRIC ACID CYCLE%SMPDB%SMP0000057 Citric Acid Cycle 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 HYPERINSULINISM-HYPERAMMONEMIA SYNDROME%PATHWHIZ%PW000072 Hyperinsulinism-Hyperammonemia Syndrome 76282 229363 69719 14719 231327 97541 216456 54342 14415 14630 268860 67417 56174 212647 14629 14661 14583 14854 14782 214579 227231 14645 BIVALIRUDIN ACTION PATHWAY%SMPDB%SMP0000277 Bivalirudin Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 DIPHENOXYLATE ACTION PATHWAY%SMPDB%SMP0000675 Diphenoxylate Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 CYPROHEPTADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059694 Cyproheptadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PHOSPHOENOLPYRUVATE CARBOXYKINASE DEFICIENCY 1 (PEPCK1)%PATHWHIZ%PW121880 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 MEVALONATE PATHWAY%SMPDB%SMP0121055 Mevalonate Pathway 110446 68603 100040592 319554 14137 16987 192156 15357 17855 110196 20775 BENZOCAINE ACTION PATHWAY%SMPDB%SMP0000392 Benzocaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCOLYSIS I%SMPDB%SMP0002312 Glycolysis I 18746 21991 100043349 56421 14751 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY%PATHWHIZ%PW122063 Glucose-6-phosphate Dehydrogenase Deficiency 14381 18641 19895 71336 21351 21881 11674 19139 14121 14751 PHOSPHOLIPID BIOSYNTHESIS%SMPDB%SMP0000025 Phospholipid Biosynthesis 18777 12660 14571 13026 192654 19210 52858 12647 56209 13139 18618 66461 14732 74451 14555 66586 19012 320951 18782 237928 74596 18806 55979 27388 FUMARASE DEFICIENCY%SMPDB%SMP0000547 Fumarase Deficiency 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 DISOPYRAMIDE ACTION PATHWAY%SMPDB%SMP0000325 Disopyramide Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 ALTERNATIVE COMPLEMENT PATHWAY%SMPDB%SMP0063815 Alternative Complement Pathway 11537 109828 230558 12279 15139 14962 18636 12266 12274 NAPROXEN ACTION PATHWAY%SMPDB%SMP0000120 Naproxen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 FLUOXETINE METABOLISM PATHWAY%SMPDB%SMP0000646 Fluoxetine Metabolism Pathway 107141 13114 56448 15567 BETAXOLOL ACTION PATHWAY%SMPDB%SMP0000299 Betaxolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 SPHINGOLIPID METABOLISM%PATHWHIZ%PW088482 Sphingolipid Metabolism 11605 268656 14466 22239 18605 22234 20773 67630 53418 56632 230379 242285 223753 70059 HYPERPHENYLALANINEMIA DUE TO 6-PYRUVOYLTETRAHYDROPTERIN SYNTHASE DEFICIENCY (PTPS)%SMPDB%SMP0000488 Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps) 110391 20751 13361 11677 12408 19286 320415 14528 CYCLOTHIAZIDE ACTION PATHWAY%SMPDB%SMP0000103 Cyclothiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 GLUCONEOGENESIS%PATHWHIZ%PW064594 Gluconeogenesis 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW122107 Triosephosphate Isomerase Deficiency 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 DEGRADATION OF SUPEROXIDES%PATHWHIZ%PW000020 Degradation of Superoxides 20656 667310 12359 22178 20657 NEBIVOLOL ACTION PATHWAY%SMPDB%SMP0000366 Nebivolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 IRINOTECAN ACTION PATHWAY%PATHWHIZ%PW000238 Irinotecan Action Pathway 104158 12038 21969 13114 436059 26357 71853 69191 18671 67838 17250 394434 12304 394436 19035 64136 12282 67397 14828 12780 BROMPHENIRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058500 Brompheniramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 KETOTIFEN H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060812 Ketotifen H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 LOSARTAN ACTION PATHWAY%PATHWHIZ%PW000282 Losartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 CETIRIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059995 Cetirizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 HEPARIN ACTION PATHWAY%SMPDB%SMP0000274 Heparin Action Pathway 12842 110135 99571 18791 18815 14161 14068 11905 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 SPIRAPRIL ACTION PATHWAY%SMPDB%SMP0000156 Spirapril Action Pathway 100038824 11606 11421 WARBURG EFFECT%SMPDB%SMP0086930 Warburg Effect 69719 55951 13806 104112 66945 67834 64602 66925 18663 20501 20916 12183 14194 15275 18293 27402 15926 11428 15929 14751 14447 17449 18746 67680 239606 66052 12974 18642 12040 19895 14661 14782 14660 100198 21351 110208 83553 11676 PREDNISONE ACTION PATHWAY%SMPDB%SMP0000440 Prednisone Action Pathway 13114 HARTNUP DISORDER%SMPDB%SMP0000189 Hartnup Disorder 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 ASTEMIZOLE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059897 Astemizole H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 VINORELBINE ACTION PATHWAY%SMPDB%SMP0000439 Vinorelbine Action Pathway 224814 76408 12575 12780 13114 18671 17250 545486 19765 22143 22059 METHDILAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059730 Methdilazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 GROWTH HORMONE SIGNALING PATHWAY%PATHWHIZ%PW064811 Growth Hormone Signaling Pathway 18750 18803 16337 20851 26413 16367 16334 15170 12703 20528 14784 14600 20111 20416 20662 20850 16452 110157 15461 26395 26417 KIDNEY FUNCTION - COLLECTING DUCT%PATHWHIZ%PW122278 Kidney Function - Collecting Duct 20276 11931 11932 20277 11933 11928 98660 11827 110935 27411 20533 100038824 11828 12346 20278 232975 ATORVASTATIN ACTION PATHWAY%SMPDB%SMP0000131 Atorvastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 GLYCEROL PHOSPHATE SHUTTLE%SMPDB%SMP0000124 Glycerol Phosphate Shuttle 14571 100043349 14555 NEPAFENAC ACTION PATHWAY%PATHWHIZ%PW000679 Nepafenac Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 RANITIDINE ACTION PATHWAY%SMPDB%SMP0000230 Ranitidine Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 DOPA-RESPONSIVE DYSTONIA%SMPDB%SMP0000486 DOPA-Responsive Dystonia 110391 20751 13361 11677 12408 19286 320415 14528 2-KETOGLUTARATE DEHYDROGENASE COMPLEX DEFICIENCY%PATHWHIZ%PW000525 2-Ketoglutarate Dehydrogenase Complex Deficiency 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 QUINETHAZONE ACTION PATHWAY%SMPDB%SMP0000091 Quinethazone Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 LEIGH SYNDROME%SMPDB%SMP0000196 Leigh Syndrome 17436 76238 18563 13382 235339 68263 18597 110446 17449 11677 60525 14651 109801 52815 11669 18770 18534 16828 107476 66204 74156 DASATINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032594 Dasatinib Inhibition of BCR-ABL 17869 56717 14784 22059 20662 20850 16452 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 INOSITOL METABOLISM%PATHWHIZ%PW064607 Inositol Metabolism 225326 18707 74055 66461 101490 234729 75669 16332 218441 277360 XIMELAGATRAN ACTION PATHWAY%SMPDB%SMP0000279 Ximelagatran Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 PROTEIN SYNTHESIS: VALINE%PATHWHIZ%PW120528 Protein Synthesis: Valine 20115 22321 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 FAS SIGNALING PATHWAY ( CD95 )%PATHWHIZ%PW070709 FAS signaling pathway ( CD95 ) 13163 12368 19090 16905 16906 14082 12633 26409 18479 11545 11857 12370 12367 13347 19645 26419 12369 26398 19249 224105 16907 26401 16476 13368 14102 20740 14103 192656 14084 ANTAZOLINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057584 Antazoline H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CINNARIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059110 Cinnarizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 MEBHYDROLIN H1-ANTIHISTAMINE ACTION%SMPDB%SMP0061052 Mebhydrolin H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PACLITAXEL ACTION PATHWAY%PATHWHIZ%PW000239 Paclitaxel Action Pathway 12780 26357 18671 17250 28253 545486 22143 PRIMARY HYPEROXALURIA TYPE I%SMPDB%SMP0000352 Primary Hyperoxaluria Type I 76282 11611 55951 18563 224805 HYPERPHENYLALANINEMIA DUE TO DHPR-DEFICIENCY%PATHWHIZ%PW000465 Hyperphenylalaninemia Due to DHPR-Deficiency 110391 20751 13361 11677 12408 19286 320415 14528 GALACTITOL AND GALACTONATE DEGRADATION%SMPDB%SMP0000840 Galactitol and Galactonate Degradation CALVIN-BENSON CYCLE%PATHWHIZ%PW012957 Calvin-Benson Cycle 19895 21991 66646 G-SECRETASE MEDIATED ERBB4 SIGNALLING PATHWAY%PATHWHIZ%PW122231 g-Secretase Mediated ErbB4 Signalling Pathway 13867 18750 11491 19164 100042150 13869 RAMIPRIL ACTION PATHWAY%SMPDB%SMP0000154 Ramipril Action Pathway 100038824 11606 11421 FONDAPARINUX ACTION PATHWAY%SMPDB%SMP0000273 Fondaparinux Action Pathway 12842 110135 99571 18791 18815 14161 14068 11905 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 IBUPROFEN ACTION PATHWAY%SMPDB%SMP0000086 Ibuprofen Action Pathway 71519 14775 208285 17001 107141 19223 13850 13114 100040843 13088 13110 71853 16993 69191 11684 67838 106648 394434 105349 12304 64292 394436 19215 19035 11689 64136 11686 12282 21391 67397 11687 14828 11688 19224 19225 18399 22236 19879 12408 71773 72303 14598 13106 72054 66469 KIDNEY FUNCTION- PROXIMAL CONVOLUTED TUBULE%SMPDB%SMP0121001 Kidney Function- Proximal Convoluted Tubule 30962 20532 54403 20544 11826 69354 50934 18399 20510 12346 102680 20518 20540 330836 17254 20539 IBANDRONATE ACTION PATHWAY%SMPDB%SMP0000079 Ibandronate Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY (APRT)%PATHWHIZ%PW000511 Adenine Phosphoribosyltransferase Deficiency (APRT) 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 EPO SIGNALING PATHWAY%PATHWHIZ%PW070692 EPO Signaling Pathway 18803 13856 13857 15170 14784 20416 20662 26419 20850 14281 16452 110157 13712 15461 16476 26395 26417 CODEINE METABOLISM PATHWAY%PATHWHIZ%PW000597 Codeine Metabolism Pathway 13114 56448 18390 RAMIPRIL METABOLISM PATHWAY%SMPDB%SMP0000597 Ramipril Metabolism Pathway 11421 LATREPIRDINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062623 Latrepirdine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW088265 Pentose Phosphate Pathway 14381 18641 19895 72157 66646 230163 21881 232449 19139 66171 14751 14121 HOP PATHWAY IN CARDIAC DEVELOPMENT%SMPDB%SMP0090879 Hop Pathway in Cardiac Development 18091 14463 20807 74318 GLUTATHIONE METABOLISM%SMPDB%SMP0000015 Glutathione Metabolism 71522 14775 12369 68252 14630 14629 14854 14782 68214 75475 16790 GAUCHER DISEASE%PATHWHIZ%PW000201 Gaucher Disease 12091 11605 14420 268656 208449 14466 22239 66190 11883 22234 50877 20773 70750 20397 19012 56632 56386 433323 53897 223753 238011 70059 171168 GABA-TRANSAMINASE DEFICIENCY%SMPDB%SMP0000351 GABA-Transaminase Deficiency 14415 268860 104776 11669 64705 99586 11754 103149 338403 PANCREAS FUNCTION - BETA CELL%PATHWHIZ%PW122285 Pancreas Function - Beta Cell 14688 56508 18750 22318 18795 16440 19339 55984 14652 271639 12286 20526 20927 14702 56808 14682 12671 12295 LANSOPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000317 Lansoprazole Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 EXCITATORY NEURAL SIGNALLING THROUGH 5-HTR 6 AND SEROTONIN%SMPDB%SMP0000312 Excitatory Neural Signalling Through 5-HTR 6 and Serotonin 14688 18749 19045 12912 14699 15565 METHADONE METABOLISM PATHWAY%SMPDB%SMP0000624 Methadone Metabolism Pathway 107141 13114 13088 56448 72303 18390 13113 14811 14810 PENTAZOCINE ACTION PATHWAY%SMPDB%SMP0000686 Pentazocine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 MECLIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059891 Meclizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 SELENOAMINO ACID METABOLISM%PATHWHIZ%PW000007 Selenoamino Acid Metabolism 107869 216443 232087 20768 23971 269378 67547 67011 14598 12411 50880 108645 GLYCOGENOSIS, TYPE VI. HERS DISEASE%PATHWHIZ%PW000531 Glycogenosis, Type VI. Hers Disease 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 ETHYLMORPHINE ACTION PATHWAY%SMPDB%SMP0000681 Ethylmorphine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCEROL METABOLISM II%PATHWHIZ%PW122618 Glycerol Metabolism II INTRACELLULAR SIGNALLING THROUGH PGD2 RECEPTOR AND PROSTAGLANDIN D2%SMPDB%SMP0000343 Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 14688 19214 210044 18749 14699 DICLOFENAC ACTION PATHWAY%PATHWHIZ%PW000135 Diclofenac Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 MOEXIPRIL METABOLISM PATHWAY%SMPDB%SMP0000595 Moexipril Metabolism Pathway 11421 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW002481 Starch and Sucrose Metabolism 66681 14376 14936 216019 15275 74185 14751 PHENYLKETONURIA%PATHWHIZ%PW000119 Phenylketonuria 107271 14204 14718 234724 14085 15445 14874 23874 66590 15233 18478 FOSPHENYTOIN (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000379 Fosphenytoin (Antiarrhythmic) Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 BUPRENORPHINE ACTION PATHWAY%SMPDB%SMP0000684 Buprenorphine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 LYSOPHOSPHATIDIC ACID LPA4 SIGNALLING%SMPDB%SMP0063756 Lysophosphatidic Acid LPA4 Signalling 14688 18795 11651 19877 432530 78134 20807 16438 14702 NADOLOL ACTION PATHWAY%PATHWHIZ%PW000371 Nadolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 ARGATROBAN ACTION PATHWAY%SMPDB%SMP0000276 Argatroban Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 TRAMADOL ACTION ACTION PATHWAY%SMPDB%SMP0000671 Tramadol Action Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 LYSOSOMAL ACID LIPASE DEFICIENCY (WOLMAN DISEASE)%PATHWHIZ%PW000099 Lysosomal Acid Lipase Deficiency (Wolman Disease) 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 SIALURIA OR FRENCH TYPE SIALURIA%SMPDB%SMP0000216 Sialuria or French Type Sialuria 15275 54342 245847 109785 67311 12764 50798 107652 56174 14583 235504 15211 71884 26384 94181 74091 19703 ISOBUTYRYL-COA DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000523 Isobutyryl-CoA Dehydrogenase Deficiency 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 THIAMINE METABOLISM%SMPDB%SMP0000076 Thiamine Metabolism 29807 105663 116914 66566 TERFENADINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061157 Terfenadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CONGENITAL LIPOID ADRENAL HYPERPLASIA (CLAH) OR LIPOID CAH%SMPDB%SMP0000371 Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 CARNITINE-ACYLCARNITINE TRANSLOCASE DEFICIENCY%PATHWHIZ%PW000493 Carnitine-Acylcarnitine Translocase Deficiency 69129 26874 14081 57279 11666 74114 12908 12896 72129 56273 CHLORPHENOXAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059836 Chlorphenoxamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 NIZATIDINE ACTION PATHWAY%SMPDB%SMP0000233 Nizatidine Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 GLYCEROL METABOLISM V (GLYCEROPHOSPHOSERINE)%PATHWHIZ%PW000918 Glycerol Metabolism V (Glycerophosphoserine) FABRY DISEASE%SMPDB%SMP0000525 Fabry Disease 12091 11605 14420 268656 208449 14466 22239 66190 11883 22234 50877 20773 70750 20397 19012 56632 56386 433323 53897 223753 238011 70059 171168 17-BETA HYDROXYSTEROID DEHYDROGENASE III DEFICIENCY%SMPDB%SMP0000356 17-beta Hydroxysteroid Dehydrogenase III Deficiency 13075 54200 100559 13074 20860 78925 208665 15497 15487 15485 ARGININEMIA%PATHWHIZ%PW000183 Argininemia 76282 55963 20514 14719 78830 18408 18416 216456 11846 11898 109900 14661 227231 CANAVAN DISEASE%SMPDB%SMP0000175 Canavan Disease 27053 69719 11898 109900 14415 268860 11565 14204 11484 70503 70223 226414 11564 66514 CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES%PATHWHIZ%PW109282 Cadmium Induces DNA Synthesis and Proliferation in Macrophages 18750 18795 110157 18751 15461 18033 18035 26413 26395 16438 19697 26417 LEVOBUNOLOL ACTION PATHWAY%SMPDB%SMP0000666 Levobunolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 MEXILETINE ACTION PATHWAY%PATHWHIZ%PW000382 Mexiletine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 STREPTOMYCIN ACTION PATHWAY%SMPDB%SMP0000259 Streptomycin Action Pathway DISULFIRAM ACTION PATHWAY%PATHWHIZ%PW000431 Disulfiram Action Pathway 11670 12359 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 68738 60525 72535 11669 13106 GROWTH HORMONE SIGNALING PATHWAY%SMPDB%SMP0120947 Growth Hormone Signaling Pathway 18750 18803 26413 20851 16334 16367 15170 20528 14784 14600 20111 20416 20850 16452 110157 15461 14599 26395 26417 3-HYDROXYISOBUTYRIC ACIDURIA%PATHWHIZ%PW000498 3-Hydroxyisobutyric Aciduria 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 ALANINE METABOLISM%SMPDB%SMP0000055 Alanine Metabolism 76282 11611 55951 18563 224805 MALONYL-COA DECARBOXYLASE DEFICIENCY%PATHWHIZ%PW000478 Malonyl-CoA Decarboxylase Deficiency 13382 110446 12039 68738 268860 12040 93747 227095 66904 110821 11364 13171 104776 56690 106557 107476 73724 CONGENITAL LACTIC ACIDOSIS%PATHWHIZ%PW000522 Congenital Lactic Acidosis 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE DEFICIENCY%PATHWHIZ%PW000063 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 GALACTOSEMIA III%SMPDB%SMP0000496 Galactosemia III 72157 74246 67883 14430 216558 22235 103988 14635 PHOSPHOLIPASE C SIGNALING PATHWAY%SMPDB%SMP0063783 Phospholipase C Signaling Pathway 18750 18795 18803 11651 22324 30955 104709 INDAPAMIDE ACTION PATHWAY%SMPDB%SMP0000110 Indapamide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 NAD+ SIGNALLING AND AGING%SMPDB%SMP0084271 NAD+ Signalling and Aging 192185 19017 226518 93759 12753 59027 18160 66454 18104 74080 19883 CONGENITAL ERYTHROPOIETIC PORPHYRIA (CEP) OR GUNTHER DISEASE%SMPDB%SMP0000345 Congenital Erythropoietic Porphyria (CEP) or Gunther Disease 22275 19044 15288 70383 22276 12892 15368 67634 17025 217721 14151 226139 109778 110006 11655 EXCITATORY NEURAL SIGNALLING THROUGH 5-HTR 7 AND SEROTONIN%SMPDB%SMP0000311 Excitatory Neural Signalling Through 5-HTR 7 and Serotonin 14688 18749 15566 19045 12912 14699 PREDNISOLONE METABOLISM PATHWAY%PATHWHIZ%PW000608 Prednisolone Metabolism Pathway 14815 15519 UREA CYCLE%PATHWHIZ%PW000162 Urea Cycle 76282 55963 20514 14719 78830 18408 18416 216456 11846 11898 109900 14661 227231 GLYCOGEN STORAGE DISEASE TYPE 1A (GSD1A) OR VON GIERKE DISEASE%SMPDB%SMP0000374 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 IBUPROFEN METABOLISM PATHWAY%PATHWHIZ%PW000566 Ibuprofen Metabolism Pathway 107141 22236 19879 13114 71853 69191 67838 394434 12304 394436 19035 64136 12282 67397 14828 19224 19225 71773 18399 72303 GLYCOLYSIS%SMPDB%SMP0087391 Glycolysis 18746 18648 21991 15275 100043349 13806 56012 319625 20525 56421 14751 STRIATED MUSCLE CONTRACTION%PATHWHIZ%PW000564 Striated Muscle Contraction 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 IMIPRAMINE METABOLISM PATHWAY%PATHWHIZ%PW000601 Imipramine Metabolism Pathway 107141 20538 13077 13114 56448 15567 AMIODARONE ACTION PATHWAY%PATHWHIZ%PW000642 Amiodarone Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 100040287 16520 19088 11554 215999 16518 67821 12288 19085 20541 19087 20650 56543 16525 16509 56808 12295 18749 20544 13383 16511 20191 20928 246133 232975 19084 20649 CHLOROPROCAINE ACTION PATHWAY%SMPDB%SMP0000394 Chloroprocaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 IMIPRAMINE ACTION PATHWAY%SMPDB%SMP0000422 Imipramine Action Pathway 20266 11931 15550 11932 11549 107141 18549 11933 20264 13077 13114 11928 98660 56808 12295 56448 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 KETOROLAC ACTION PATHWAY%SMPDB%SMP0000098 Ketorolac Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 NICOTINE METABOLISM PATHWAY%PATHWHIZ%PW000604 Nicotine Metabolism Pathway 14262 394433 13088 13087 11761 11444 110834 11438 394434 CARNITINE SYNTHESIS%SMPDB%SMP0000465 Carnitine Synthesis 20425 56752 170442 73251 192289 FAMILIAL LIPOPROTEIN LIPASE DEFICIENCY%PATHWHIZ%PW000506 Familial Lipoprotein Lipase Deficiency 15450 50784 14571 11670 11677 19012 235582 14732 55979 14555 16956 ETHYLMALONIC ENCEPHALOPATHY%PATHWHIZ%PW000106 Ethylmalonic Encephalopathy 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 TIAPROFENIC ACID ACTION PATHWAY%PATHWHIZ%PW000682 Tiaprofenic Acid Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 BUMETANIDE ACTION PATHWAY%SMPDB%SMP0000088 Bumetanide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 GLYCEROL METABOLISM%PATHWHIZ%PW000914 Glycerol Metabolism BCR-ABL ACTION IN CML PATHOGENESIS%SMPDB%SMP0031692 BCR-ABL Action in CML Pathogenesis 17869 56717 14784 22059 20662 20850 16452 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 GLUTAMATE METABOLISM%PATHWHIZ%PW000003 Glutamate Metabolism 76282 229363 69719 14719 231327 97541 216456 54342 14415 14630 268860 67417 56174 212647 14629 14661 14583 14854 14782 214579 227231 14645 XANTHINURIA TYPE I%SMPDB%SMP0000512 Xanthinuria Type I 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 GLYCOGENOSIS, TYPE IV. AMYLOPECTINOSIS, ANDERSON DISEASE%SMPDB%SMP0000554 Glycogenosis, Type IV. Amylopectinosis, Anderson Disease 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 AZATHIOPRINE ACTION PATHWAY%SMPDB%SMP0000427 Azathioprine Action Pathway 63959 15452 19353 75456 27416 239273 11564 16434 11486 23984 67054 67979 11636 229363 210044 13340 14450 269346 54369 22017 76952 11534 238871 53893 231327 11761 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 114304 GLUTARIC ACIDURIA TYPE I%SMPDB%SMP0000185 Glutaric Aciduria Type I 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 GLUTARIC ACIDURIA TYPE I%SMPDB%SMP0000186 Glutaric Aciduria Type I 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 BETAZOLE ACTION PATHWAY%PATHWHIZ%PW000713 Betazole Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 TENOFOVIR METABOLISM PATHWAY%PATHWHIZ%PW000606 Tenofovir Metabolism Pathway 11636 18103 18102 11637 3-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000718 3-beta-Hydroxysteroid Dehydrogenase Deficiency 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 MERCAPTOPURINE ACTION PATHWAY%PATHWHIZ%PW000267 Mercaptopurine Action Pathway 63959 15452 19353 75456 27416 239273 11564 16434 11486 23984 67054 67979 11636 229363 210044 13340 14450 269346 54369 22017 76952 11534 238871 53893 231327 11761 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 114304 CYSTEINE METABOLISM%PATHWHIZ%PW000018 Cysteine Metabolism 107869 14630 14718 14629 12583 83429 27267 246221 16828 MEFENAMIC ACID ACTION PATHWAY%PATHWHIZ%PW000261 Mefenamic Acid Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 EGF SIGNALLING PATHWAY%SMPDB%SMP0063810 EGF Signalling Pathway 18750 18803 13649 18751 14784 20416 26419 14281 26398 110157 13712 15461 26401 16476 26395 26417 20807 20847 20846 20848 16451 100039026 13645 20662 218397 20852 FOLATE METABOLISM%SMPDB%SMP0000053 Folate Metabolism 107747 14317 13361 17768 100039707 270685 14287 52466 17769 69606 108156 667301 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0087296 Fructose and Mannose Degradation 21991 11674 14121 18641 20322 16548 11677 218138 69080 67883 29858 18639 110119 BEPOTASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060058 Bepotastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ARBEKACIN ACTION PATHWAY%PATHWHIZ%PW000690 Arbekacin Action Pathway FAMOTIDINE ACTION PATHWAY%SMPDB%SMP0000231 Famotidine Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 MAGNESIUM SALICYLATE ACTION PATHWAY%PATHWHIZ%PW000675 Magnesium Salicylate Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 GAMMA-CYSTATHIONASE DEFICIENCY (CTH)%PATHWHIZ%PW000490 gamma-Cystathionase Deficiency (CTH) 107869 12411 VITAMIN B6 METABOLISM%PATHWHIZ%PW000053 Vitamin B6 Metabolism 57028 216134 11647 103711 11761 NUCLEOTIDE SUGARS METABOLISM%SMPDB%SMP0087384 Nucleotide Sugars Metabolism 72157 74246 67883 69976 14430 216558 22235 15275 EMBRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062622 Embramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ATENOLOL ACTION PATHWAY%SMPDB%SMP0000298 Atenolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 RESCINNAMINE ACTION PATHWAY%SMPDB%SMP0000155 Rescinnamine Action Pathway 100038824 11606 11421 PROPIONIC ACIDEMIA%PATHWHIZ%PW000062 Propionic Acidemia 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 5-OXOPROLINASE DEFICIENCY%PATHWHIZ%PW000476 5-Oxoprolinase Deficiency 71522 14775 12369 68252 14630 14629 14854 14782 68214 75475 16790 PROTEIN SYNTHESIS: METHIONINE%PATHWHIZ%PW112933 Protein Synthesis: Methionine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 216443 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 GLUCONEOGENESIS FROM L-MALIC ACID%SMPDB%SMP0000839 Gluconeogenesis from L-Malic Acid CAPECITABINE METABOLISM PATHWAY%SMPDB%SMP0000607 Capecitabine Metabolism Pathway 434203 104158 72269 72962 22171 DEXBROMPHENIRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058503 Dexbrompheniramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 RIBOFLAVIN METABOLISM%SMPDB%SMP0000070 Riboflavin Metabolism 18605 22173 54391 319945 11431 ACETYLSALICYLIC ACID ACTION PATHWAY%PATHWHIZ%PW000128 Acetylsalicylic Acid Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 MORPHINE ACTION PATHWAY%PATHWHIZ%PW000412 Morphine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 71853 69191 67838 98660 394434 12304 394436 19035 64136 12282 67397 14828 231396 56808 12295 22236 12286 13162 71773 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 MITOCHONDRIAL BETA-OXIDATION OF SHORT CHAIN SATURATED FATTY ACIDS%PATHWHIZ%PW000171 Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids 110446 15107 11409 15108 52538 93747 11363 ORNITHINE TRANSCARBAMYLASE DEFICIENCY (OTC DEFICIENCY)%SMPDB%SMP0000205 Ornithine Transcarbamylase Deficiency (OTC Deficiency) 76282 55963 20514 14719 78830 18408 18416 216456 11846 11898 109900 14661 227231 PROPRANOLOL ACTION PATHWAY%SMPDB%SMP0000307 Propranolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 FATTY ACID METABOLISM%PATHWHIZ%PW000023 Fatty Acid Metabolism 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 VALINE, LEUCINE, AND ISOLEUCINE DEGRADATION%PATHWHIZ%PW000051 Valine, Leucine, and Isoleucine Degradation 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 3-METHYLGLUTACONIC ACIDURIA TYPE I%SMPDB%SMP0000139 3-Methylglutaconic Aciduria Type I 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 DIMETINDENE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057582 Dimetindene H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PLASMALOGEN SYNTHESIS%PATHWHIZ%PW000170 Plasmalogen Synthesis 19012 14712 99712 228061 55979 SULFITE OXIDASE DEFICIENCY%PATHWHIZ%PW000508 Sulfite Oxidase Deficiency 58250 54200 20887 23827 211389 23972 CARNITINE PALMITOYL TRANSFERASE DEFICIENCY I%PATHWHIZ%PW000514 Carnitine Palmitoyl Transferase Deficiency I 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 BENAZEPRIL ACTION PATHWAY%SMPDB%SMP0000145 Benazepril Action Pathway 100038824 11606 11421 CIMETIDINE METABOLISM PATHWAY%PATHWHIZ%PW000593 Cimetidine Metabolism Pathway 15466 CELECOXIB METABOLISM PATHWAY%SMPDB%SMP0000644 Celecoxib Metabolism Pathway 19224 19225 13114 56448 394434 ADEFOVIR DIPIVOXIL METABOLISM PATHWAY%PATHWHIZ%PW000605 Adefovir Dipivoxil Metabolism Pathway 11636 18103 18102 11637 CHILD SYNDROME%PATHWHIZ%PW000096 CHILD Syndrome 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 TREHALOSE DEGRADATION%PATHWHIZ%PW000169 Trehalose Degradation 20537 11931 11932 58866 11933 11928 103988 98660 20526 232975 PYRUVATE METABOLISM%PATHWHIZ%PW000054 Pyruvate Metabolism 17436 76238 18563 13382 235339 68263 18597 110446 17449 11677 60525 14651 109801 52815 11669 18770 18534 16828 107476 66204 74156 HYPERPROLINEMIA TYPE II%SMPDB%SMP0000360 Hyperprolinemia Type II 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 CITALOPRAM METABOLISM PATHWAY%PATHWHIZ%PW000603 Citalopram Metabolism Pathway 109731 107141 17161 56448 15567 11761 13113 ACETAMINOPHEN ACTION PATHWAY%SMPDB%SMP0000710 Acetaminophen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 TORSEMIDE ACTION PATHWAY%PATHWHIZ%PW000338 Torsemide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 2-AMINOADIPIC 2-OXOADIPIC ACIDURIA%SMPDB%SMP0000719 2-Aminoadipic 2-Oxoadipic Aciduria 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 FENTANYL ACTION PATHWAY%PATHWHIZ%PW000421 Fentanyl Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLUCOSE-ALANINE CYCLE%SMPDB%SMP0000127 Glucose-Alanine Cycle 76282 69354 55963 68267 14661 108682 20526 20528 GEMCITABINE METABOLISM PATHWAY%PATHWHIZ%PW000579 Gemcitabine Metabolism Pathway 63959 434203 13178 18102 50773 320685 66588 20135 20133 382985 22171 51797 114304 WARBURG EFFECT%PATHWHIZ%PW000630 Warburg Effect 55951 100043349 216456 13806 56012 66171 18655 18770 16828 20514 66945 18563 67834 56451 66925 20501 209692 20917 11429 13382 14194 230163 235339 21881 20526 68263 15926 170718 11428 18597 14751 15929 78920 14381 17449 18641 18746 67680 66052 12974 19895 14661 15277 21351 110208 ENALAPRIL METABOLISM PATHWAY%SMPDB%SMP0000593 Enalapril Metabolism Pathway 11421 TAY-SACHS DISEASE%PATHWHIZ%PW000215 Tay-Sachs Disease 15275 54342 245847 109785 67311 12764 50798 107652 56174 14583 235504 15211 71884 26384 94181 74091 19703 BOSUTINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032596 Bosutinib Inhibition of BCR-ABL 17869 56717 14784 22059 20662 20850 16452 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 WARBURG EFFECT%SMPDB%SMP0087527 Warburg Effect 55951 18598 229699 20511 74419 100043349 216456 13806 18655 66945 67834 18563 56451 209692 20917 11429 14194 13382 235339 68263 170718 15926 56421 11428 14751 17449 14381 18746 67680 12974 14661 19895 15277 21351 110208 HYPERMETHIONINEMIA%SMPDB%SMP0000341 Hypermethioninemia 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 G(M2)-GANGLIOSIDOSIS: VARIANT B, TAY-SACHS DISEASE%SMPDB%SMP0000534 G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease 15275 54342 245847 109785 67311 12764 50798 107652 56174 14583 235504 15211 71884 26384 94181 74091 19703 KANDUTSCH-RUSSELL PATHWAY (CHOLESTEROL BIOSYNTHESIS)%SMPDB%SMP0121060 Kandutsch-Russell Pathway (Cholesterol Biosynthesis) 66234 235293 18194 98386 13121 13360 15490 13595 74754 ARGININE AND PROLINE METABOLISM%SMPDB%SMP0000020 Arginine and Proline Metabolism 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 LYMECYCLINE ACTION PATHWAY%SMPDB%SMP0000295 Lymecycline Action Pathway LEVALLORPHAN ACTION PATHWAY%SMPDB%SMP0000683 Levallorphan Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 FLUVASTATIN ACTION PATHWAY%PATHWHIZ%PW000274 Fluvastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 STAT3 SIGNALING PATHWAY%PATHWHIZ%PW068597 Stat3 Signaling Pathway 56717 26413 54721 20848 16451 IBUTILIDE ACTION PATHWAY%SMPDB%SMP0000332 Ibutilide Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 HEROIN METABOLISM PATHWAY%PATHWHIZ%PW000599 Heroin Metabolism Pathway 104158 12038 436059 18390 INOSITOL METABOLISM%PATHWHIZ%PW088478 Inositol Metabolism 69718 56208 225326 71780 55980 66461 234729 242291 18706 104015 18798 12462 ADENOSINE DEAMINASE DEFICIENCY%PATHWHIZ%PW000075 Adenosine Deaminase Deficiency 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 RAS SIGNALING PATHWAY%SMPDB%SMP0063784 Ras Signaling Pathway 670717 19353 19765 18706 11783 57257 11848 12675 12371 110157 56044 13712 54601 15461 11651 18805 19730 12048 17127 17128 26395 12015 26417 PANTOPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000318 Pantoprazole Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 PIRENZEPINE ACTION PATHWAY%SMPDB%SMP0000246 Pirenzepine Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 ORPHENADRINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059735 Orphenadrine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 EBASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061153 Ebastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ALDOSTERONE FROM STEROIDOGENESIS%SMPDB%SMP0121126 Aldosterone from Steroidogenesis 14688 13070 11607 13079 15497 14702 14682 13072 SPIRONOLACTONE ACTION PATHWAY%SMPDB%SMP0000134 Spironolactone Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 TRANSALDOLASE DEFICIENCY%SMPDB%SMP0000520 Transaldolase Deficiency 21881 11674 66171 14751 14121 75456 14381 18641 19895 72157 71336 21351 66646 110208 232449 CATECHOLAMINE BIOSYNTHESIS%SMPDB%SMP0000012 Catecholamine Biosynthesis 21823 18948 13195 ERLOTINIB ACTION PATHWAY%PATHWHIZ%PW000251 Erlotinib Action Pathway 13649 26357 18671 NIFEDIPINE ACTION PATHWAY%PATHWHIZ%PW000394 Nifedipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 BETA-MERCAPTOLACTATE-CYSTEINE DISULFIDURIA%SMPDB%SMP0000499 beta-Mercaptolactate-Cysteine Disulfiduria 107869 14630 14718 14629 12583 83429 27267 246221 16828 ETHACRYNIC ACID ACTION PATHWAY%SMPDB%SMP0000097 Ethacrynic Acid Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 GLYCOLYSIS AND PYRUVATE DEHYDROGENASE%SMPDB%SMP0000807 Glycolysis and Pyruvate Dehydrogenase CHLOROTHIAZIDE ACTION PATHWAY%SMPDB%SMP0000078 Chlorothiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 ABCIXIMAB ACTION PATHWAY%SMPDB%SMP0000265 Abciximab Action Pathway 16416 16399 BENAZEPRIL METABOLISM PATHWAY%SMPDB%SMP0000591 Benazepril Metabolism Pathway 11421 LEVORPHANOL ACTION PATHWAY%SMPDB%SMP0000673 Levorphanol Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 LYSOPHOSPHATIDIC ACID LPA5 SIGNALLING%SMPDB%SMP0063757 Lysophosphatidic Acid LPA5 Signalling 14688 18795 11651 19877 432530 20807 16438 381810 14702 MEPIVACAINE ACTION PATHWAY%PATHWHIZ%PW000405 Mepivacaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 MELOXICAM ACTION PATHWAY%SMPDB%SMP0000106 Meloxicam Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 METHYCLOTHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000327 Methyclothiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 IFOSFAMIDE ACTION PATHWAY%PATHWHIZ%PW000249 Ifosfamide Action Pathway 11670 11668 13114 13088 13087 72303 BILE ACID DIRECT SIGNALLING PATHWAY (2)%PATHWHIZ%PW090771 Bile Acid Direct Signalling Pathway (2) 14652 227289 20494 NALOXONE ACTION PATHWAY%SMPDB%SMP0000688 Naloxone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 UROKINASE ACTION PATHWAY%SMPDB%SMP0000284 Urokinase Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 INSULIN SIGNALLING%PATHWHIZ%PW000454 Insulin Signalling 56458 384783 18607 16337 26413 16367 16334 20528 14784 20416 20662 26419 110157 15461 11651 26395 30955 104709 26396 SUPROFEN ACTION PATHWAY%SMPDB%SMP0000101 Suprofen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 HYDROCHLOROTHIAZIDE ACTION PATHWAY%SMPDB%SMP0000100 Hydrochlorothiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 PYRUVATE KINASE DEFICIENCY%PATHWHIZ%PW000535 Pyruvate Kinase Deficiency 17436 76238 18563 13382 235339 68263 18597 110446 17449 11677 60525 14651 109801 52815 11669 18770 18534 16828 107476 66204 74156 PROTEIN SYNTHESIS: LEUCINE%SMPDB%SMP0111873 Protein Synthesis: Leucine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 107045 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 INOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0087496 Inositol Phosphate Metabolism 69718 327655 71780 55980 242291 56409 27399 104015 WARFARIN ACTION PATHWAY%SMPDB%SMP0000268 Warfarin Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 GLUCONEOGENESIS FROM L-MALIC ACID%PATHWHIZ%PW002518 Gluconeogenesis from L-Malic Acid 17449 TIMOLOL ACTION PATHWAY%PATHWHIZ%PW000636 Timolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 ADRENOLEUKODYSTROPHY, X-LINKED%PATHWHIZ%PW000492 Adrenoleukodystrophy, X-Linked 69129 26874 14081 57279 11666 74114 12908 12896 72129 56273 ANTIPYRINE ACTION PATHWAY%SMPDB%SMP0000692 Antipyrine Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 HYDROXYETHYLPROMETHAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059710 Hydroxyethylpromethazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 HYPERCHOLESTEROLEMIA%PATHWHIZ%PW000221 Hypercholesterolemia 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 INOSITOL METABOLISM%SMPDB%SMP0002397 Inositol Metabolism 56208 18802 225326 55980 234729 75669 104015 DIHYDROPYRIMIDINE DEHYDROGENASE DEFICIENCY (DHPD)%SMPDB%SMP0000179 Dihydropyrimidine Dehydrogenase Deficiency (DHPD) 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 GLYCOGENOSIS, TYPE IA. VON GIERKE DISEASE%PATHWHIZ%PW121901 Glycogenosis, Type IA. Von Gierke Disease 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 TOCAINIDE ACTION PATHWAY%SMPDB%SMP0000330 Tocainide Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 ALTEPLASE ACTION PATHWAY%PATHWHIZ%PW000302 Alteplase Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 TIROFIBAN ACTION PATHWAY%PATHWHIZ%PW000293 Tirofiban Action Pathway 16416 16399 GAMMA-GLUTAMYLTRANSPEPTIDASE DEFICIENCY%SMPDB%SMP0000501 gamma-Glutamyltranspeptidase Deficiency 71522 14775 12369 68252 14630 14629 14854 14782 68214 75475 16790 TICLOPIDINE ACTION PATHWAY%SMPDB%SMP0000261 Ticlopidine Action Pathway 70839 FAMILIAL HYPERCHOLANEMIA (FHCA)%PATHWHIZ%PW000194 Familial Hypercholanemia (FHCA) 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 IMINOGLYCINURIA%PATHWHIZ%PW000219 Iminoglycinuria 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 FLURBIPROFEN ACTION PATHWAY%SMPDB%SMP0000697 Flurbiprofen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 DOPAMINE ACTIVATION OF NEUROLOGICAL REWARD SYSTEM%PATHWHIZ%PW000440 Dopamine Activation of Neurological Reward System 210044 18749 13488 LAFUTIDINE H2-ANTIHISTAMINE ACTION%PATHWHIZ%PW051946 Lafutidine H2-Antihistamine Action 20608 12346 15466 11944 11945 20604 14459 12426 12671 CARBAMAZEPINE METABOLISM PATHWAY%PATHWHIZ%PW000610 Carbamazepine Metabolism Pathway 107141 13849 13114 13088 72303 13113 P53 SIGNALING PATHWAY%PATHWHIZ%PW064774 P53 Signaling Pathway 12043 12566 12534 12447 13555 17873 12443 18538 12028 11783 19645 12567 12575 METOLAZONE ACTION PATHWAY%SMPDB%SMP0000105 Metolazone Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 GLYCOGEN SYNTHETASE DEFICIENCY%PATHWHIZ%PW122096 Glycogen Synthetase Deficiency 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 OXATOMIDE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059044 Oxatomide H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 COMPLEMENT PATHWAY%PATHWHIZ%PW064819 Complement Pathway 230558 12279 15139 14962 12266 12274 11537 12258 109828 625018 12259 12260 12262 667277 317677 12263 17195 17175 MIZOLASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060230 Mizolastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PHENINDAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW062141 Phenindamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 LYSINURIC PROTEIN INTOLERANCE%SMPDB%SMP0000197 Lysinuric Protein Intolerance 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 UBIQUITIN–PROTEASOME PATHWAY%SMPDB%SMP0063816 Ubiquitin–Proteasome Pathway 19166 19167 26441 56424 26442 22194 23997 24108 19185 22201 26445 26446 19172 19173 19175 19177 67089 26443 26444 19170 19179 22190 19181 19182 23996 19184 26440 D-GLYCERIC ACIDURA%PATHWHIZ%PW000505 D-Glyceric Acidura 15450 50784 14571 11670 11677 19012 235582 14732 55979 14555 16956 GNRH SIGNALING PATHWAY%SMPDB%SMP0120949 GnRH Signaling Pathway 18750 18795 18751 14784 26419 110157 13712 15461 60595 16476 26401 14714 18805 14715 26400 14672 17390 26395 224129 12322 12313 17387 14308 16866 13869 20779 11911 13653 12640 242274 12540 15200 26413 16438 CAFFEINE METABOLISM%SMPDB%SMP0000028 Caffeine Metabolism 17960 13077 13114 13087 72303 22436 13106 ANILERIDINE ACTION PATHWAY%SMPDB%SMP0000674 Anileridine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 CODEINE ACTION PATHWAY%PATHWHIZ%PW000411 Codeine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 13114 11928 98660 56808 12295 56448 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 HYPERLYSINEMIA I, FAMILIAL%PATHWHIZ%PW000503 Hyperlysinemia I, Familial 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 ADRENAL HYPERPLASIA TYPE 3 OR CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY%SMPDB%SMP0000373 Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 RETEPLASE ACTION PATHWAY%SMPDB%SMP0000285 Reteplase Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 FRUCTOSE INTOLERANCE, HEREDITARY%PATHWHIZ%PW000702 Fructose Intolerance, Hereditary 234730 75454 22122 21991 75540 331026 15275 230163 11674 14121 18641 20322 11677 16548 218138 29858 18639 110119 BUPRANOLOL ACTION PATHWAY%SMPDB%SMP0000670 Bupranolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 PROPOXYPHENE ACTION PATHWAY%PATHWHIZ%PW000649 Propoxyphene Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCOLYSIS%PATHWHIZ%PW088465 Glycolysis 18746 15277 100043349 13806 56421 14751 BCR SIGNALING PATHWAY%PATHWHIZ%PW070885 BCR Signaling Pathway 18750 18803 18751 20963 19353 17060 14784 17096 15985 109305 20416 26419 14281 110157 13712 15461 26401 16476 26395 19055 26417 19056 12229 12518 18021 73181 18018 18019 20662 19057 640703 22324 LYSOPHOSPHATIDIC ACID LPA1 SIGNALLING%SMPDB%SMP0063746 Lysophosphatidic Acid LPA1 Signalling 14688 18795 14745 11651 19877 432530 20807 16438 14702 PROCAINE ACTION PATHWAY%PATHWHIZ%PW000408 Procaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCOGENOSIS, TYPE IC%SMPDB%SMP0000574 Glycogenosis, Type IC 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 OLOPATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060740 Olopatadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 KETONE BODY METABOLISM%PATHWHIZ%PW000028 Ketone Body Metabolism 110446 71911 15356 67041 ASPARTATE METABOLISM%SMPDB%SMP0000067 Aspartate Metabolism 27053 69719 11898 109900 14415 268860 11565 14204 11484 70503 70223 226414 11564 66514 LUMIRACOXIB ACTION PATHWAY%SMPDB%SMP0000699 Lumiracoxib Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 NILOTINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032595 Nilotinib Inhibition of BCR-ABL 17869 56717 14784 22059 20662 20850 16452 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 STREPTOKINASE ACTION PATHWAY%PATHWHIZ%PW000304 Streptokinase Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 TENIPOSIDE METABOLISM PATHWAY%SMPDB%SMP0000602 Teniposide Metabolism Pathway 17523 13114 21973 PHOSPHATIDYLCHOLINE BIOSYNTHESIS%SMPDB%SMP0014212 Phosphatidylcholine Biosynthesis 12660 13026 68671 18618 320951 99712 HYPERORNITHINEMIA WITH GYRATE ATROPHY (HOGA)%PATHWHIZ%PW000481 Hyperornithinemia with Gyrate Atrophy (HOGA) 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 INOSITOL METABOLISM%PATHWHIZ%PW088261 Inositol Metabolism 224020 228550 83493 56208 16329 71780 228361 55980 66461 217837 56727 234729 75669 17330 18706 12462 18799 APOPTOTIC DNA FRAGMENTATION AND TISSUE HOMEOSTASIS%SMPDB%SMP0063772 Apoptotic DNA Fragmentation and Tissue Homeostasis 12369 69719 21973 97165 434174 14939 13804 12367 13347 GLYCEROL METABOLISM II%PATHWHIZ%PW000915 Glycerol Metabolism II GLUCONEOGENESIS%SMPDB%SMP0087318 Gluconeogenesis 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 CLEMASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059823 Clemastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 EPTIFIBATIDE ACTION PATHWAY%PATHWHIZ%PW000292 Eptifibatide Action Pathway 16416 16399 CYCLIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059857 Cyclizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE, PKA%SMPDB%SMP0063764 Activation of cAMP-dependent protein kinase, PKA 14688 18749 19088 14699 271639 18747 19085 19087 19084 GLUCONEOGENESIS%PATHWHIZ%PW000152 Gluconeogenesis 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 ZELLWEGER SYNDROME%PATHWHIZ%PW000195 Zellweger Syndrome 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 ANISTREPLASE ACTION PATHWAY%PATHWHIZ%PW000303 Anistreplase Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 PROTEIN SYNTHESIS: LYSINE%SMPDB%SMP0111874 Protein Synthesis: Lysine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 85305 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 DICUMAROL ACTION PATHWAY%PATHWHIZ%PW000313 Dicumarol Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW088490 Pentose Phosphate Pathway 14381 72157 19895 71336 74419 21351 66646 232449 56421 19139 14751 14121 TYROSINEMIA TYPE I%PATHWHIZ%PW000182 Tyrosinemia Type I 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 TOLPROPAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062621 Tolpropamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 GLYCOGEN SYNTHETASE DEFICIENCY%PATHWHIZ%PW000528 Glycogen Synthetase Deficiency 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 MUCOPOLYSACCHARIDOSIS VII. SLY SYNDROME%PATHWHIZ%PW121876 Mucopolysaccharidosis VII. Sly Syndrome 110006 22239 15275 14751 CLASSICAL COMPLEMENT PATHWAY%PATHWHIZ%PW065057 Classical Complement Pathway 230558 12279 15139 12266 12274 109828 625018 12259 12260 12262 667277 317677 12263 GLYCOGENOSIS, TYPE IA. VON GIERKE DISEASE%SMPDB%SMP0000581 Glycogenosis, Type IA. Von Gierke Disease 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 GLYCOLYSIS%PATHWHIZ%PW088241 Glycolysis 12183 21991 100043349 14377 13806 230163 56012 319625 20526 14751 18746 18648 18642 FRUCTOSE METABOLISM%SMPDB%SMP0012445 Fructose Metabolism 20322 15275 11674 18640 14121 CHLOROPYRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058510 Chloropyramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PIMETHIXENE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062886 Pimethixene H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ALCAFTADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062881 Alcaftadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 REPAGLINIDE ACTION PATHWAY%SMPDB%SMP0000454 Repaglinide Action Pathway 20927 16334 12286 20526 56808 12295 STARCH AND SUCROSE METABOLISM%SMPDB%SMP0063673 Starch and Sucrose Metabolism 110006 22239 15275 14751 NICOTINATE AND NICOTINAMIDE METABOLISM%PATHWHIZ%PW000151 Nicotinate and Nicotinamide Metabolism 192185 67375 78914 226518 18113 225994 12182 59027 67993 76952 11761 18605 18950 18115 SALSALATE ACTION PATHWAY%SMPDB%SMP0000707 Salsalate Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 TELITHROMYCIN ACTION PATHWAY%PATHWHIZ%PW000350 Telithromycin Action Pathway TYROSINE METABOLISM%SMPDB%SMP0000006 Tyrosine Metabolism 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 ACUTE INTERMITTENT PORPHYRIA%PATHWHIZ%PW000174 Acute Intermittent Porphyria 22275 19044 15288 70383 22276 12892 15368 67634 17025 217721 14151 226139 109778 110006 11655 PORPHYRIA VARIEGATA (PV)%SMPDB%SMP0000346 Porphyria Variegata (PV) 22275 19044 15288 70383 22276 12892 15368 67634 17025 217721 14151 226139 109778 110006 11655 ISOPRENALINE ACTION PATHWAY%SMPDB%SMP0000663 Isoprenaline Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 AMLODIPINE ACTION PATHWAY%PATHWHIZ%PW000391 Amlodipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 PIROXICAM ACTION PATHWAY%SMPDB%SMP0000077 Piroxicam Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 CILAZAPRIL METABOLISM PATHWAY%SMPDB%SMP0000592 Cilazapril Metabolism Pathway 11421 ACRIVASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060826 Acrivastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 FRUCTOSE METABOLISM%PATHWHIZ%PW002390 Fructose Metabolism 20322 15275 18640 14751 ETOPOSIDE ACTION PATHWAY%SMPDB%SMP0000442 Etoposide Action Pathway 13114 21974 71853 69191 18671 67838 12304 394436 19035 64136 12282 76408 67397 14828 19224 17523 19225 21973 IMATINIB INHIBITION OF BCR-ABL%SMPDB%SMP0031694 Imatinib Inhibition of BCR-ABL 17869 56717 18671 14784 22059 20662 20850 16452 20517 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 SALLA DISEASE INFANTILE SIALIC ACID STORAGE DISEASE%SMPDB%SMP0000240 Salla Disease Infantile Sialic Acid Storage Disease 15275 54342 245847 109785 67311 12764 50798 107652 56174 14583 235504 15211 71884 26384 94181 74091 19703 DIBUCAINE ACTION PATHWAY%SMPDB%SMP0000396 Dibucaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 PROLINEMIA TYPE II%PATHWHIZ%PW000087 Prolinemia Type II 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 TRYPTOPHAN METABOLISM%SMPDB%SMP0000063 Tryptophan Metabolism 12359 107766 70560 56720 98256 71562 22375 21990 11298 70789 266645 13195 21743 13076 23923 15930 11669 LPS AND CITRATE SIGNALING AND INFLAMMATION%PATHWHIZ%PW101069 LPS and Citrate Signaling and Inflammation 17436 104112 66945 66925 56421 17449 67680 66052 12675 12475 12974 117149 17087 21898 22034 13358 18033 17874 18035 16151 16150 19697 107476 HYPERGLYCINEMIA, NON-KETOTIC%SMPDB%SMP0000485 Hyperglycinemia, Non-Ketotic 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 CORTICOSTERONE METHYL OXIDASE I DEFICIENCY (CMO I)%PATHWHIZ%PW000553 Corticosterone Methyl Oxidase I Deficiency (CMO I) 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 STEROID BIOSYNTHESIS%PATHWHIZ%PW000050 Steroid Biosynthesis 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 VASOPRESSIN REGULATION OF WATER HOMEOSTASIS%PATHWHIZ%PW000447 Vasopressin Regulation of Water Homeostasis 14701 14688 14309 210044 18749 14699 12000 COAGULATION%SMPDB%SMP0000586 Coagulation 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 ACENOCOUMAROL ACTION PATHWAY%PATHWHIZ%PW000312 Acenocoumarol Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 ETHANOL DEGRADATION%PATHWHIZ%PW000021 Ethanol Degradation 68738 12359 60525 72535 11669 13106 MINOCYCLINE ACTION PATHWAY%PATHWHIZ%PW000360 Minocycline Action Pathway STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW088364 Starch and Sucrose Metabolism 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 GLYCEROL KINASE DEFICIENCY%SMPDB%SMP0000187 Glycerol Kinase Deficiency 15450 50784 14571 11670 11677 19012 235582 14732 55979 14555 16956 PROTEIN SYNTHESIS: GLYCINE%PATHWHIZ%PW112928 Protein Synthesis: Glycine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 353172 27050 27370 GALACTOSEMIA%PATHWHIZ%PW000200 Galactosemia 11677 72157 74246 14430 226413 216558 12091 14387 11605 15275 14377 14595 BLOCH PATHWAY (CHOLESTEROL BIOSYNTHESIS)%SMPDB%SMP0121057 Bloch Pathway (Cholesterol Biosynthesis) 66234 235293 18194 98386 13121 13360 15490 13595 74754 TYROSINEMIA TYPE 2 (OR RICHNER-HANHART SYNDROME)%SMPDB%SMP0000369 Tyrosinemia Type 2 (or Richner-Hanhart Syndrome) 107271 14204 14718 234724 14085 15445 14874 23874 66590 15233 18478 VALDECOXIB ACTION PATHWAY%SMPDB%SMP0000116 Valdecoxib Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 SALICYLATE-SODIUM ACTION PATHWAY%SMPDB%SMP0000708 Salicylate-Sodium Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 DOCETAXEL ACTION PATHWAY%PATHWHIZ%PW000240 Docetaxel Action Pathway 12780 26357 18671 17250 28253 545486 22143 SEPIAPTERIN REDUCTASE DEFICIENCY%PATHWHIZ%PW000467 Sepiapterin Reductase Deficiency 110391 20751 13361 11677 12408 19286 320415 14528 HYPER-IGD SYNDROME%SMPDB%SMP0000509 Hyper-IgD Syndrome 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 TRIPROLIDINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057581 Triprolidine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CORTICOSTERONE METHYL OXIDASE II DEFICIENCY (CMO II)%SMPDB%SMP0000578 Corticosterone Methyl Oxidase II Deficiency (CMO II) 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 NAD+ SIGNALLING PATHWAY (CANCER)%PATHWHIZ%PW084315 NAD+ Signalling Pathway (Cancer) 192185 226518 93759 59027 66454 12494 71361 18104 74080 22059 OLMESARTAN ACTION PATHWAY%SMPDB%SMP0000163 Olmesartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 GLUTAMINOLYSIS AND CANCER%SMPDB%SMP0002298 Glutaminolysis and Cancer 55951 216456 20540 209837 56309 16828 17436 269951 55963 104112 20514 66945 18563 14719 67834 56451 66925 20501 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 67680 66052 12974 14661 PHOTOSYNTHESIS%SMPDB%SMP0012089 Photosynthesis 19895 21991 66646 KIDNEY FUNCTION - ASCENDING LIMB OF THE LOOP OF HENLE%PATHWHIZ%PW122277 Kidney Function - Ascending Limb of The Loop of Henle 11931 20495 11932 56365 11933 100038824 11928 98660 232975 107723 FRUCTOSE METABOLISM%PATHWHIZ%PW122616 Fructose Metabolism AMILORIDE ACTION PATHWAY%SMPDB%SMP0000133 Amiloride Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 METHOTREXATE ACTION PATHWAY%SMPDB%SMP0000432 Methotrexate Action Pathway 107747 14317 13361 17768 100039707 270685 14287 52466 17769 69606 108156 667301 GLYCOGENOSIS, TYPE III. CORI DISEASE, DEBRANCHER GLYCOGENOSIS%PATHWHIZ%PW000529 Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 SALICYLIC ACID ACTION PATHWAY%SMPDB%SMP0000709 Salicylic Acid Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 CITRULLINEMIA TYPE I%PATHWHIZ%PW000185 Citrullinemia Type I 76282 55963 20514 14719 78830 18408 18416 216456 11846 11898 109900 14661 227231 AZELASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060741 Azelastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PROMETHAZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060150 Promethazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY (MTHFRD)%SMPDB%SMP0000340 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 RABEPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000592 Rabeprazole Metabolism Pathway 11944 11945 DIMETHYLTHIAMBUTENE ACTION PATHWAY%SMPDB%SMP0000680 Dimethylthiambutene Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 RABEPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000319 Rabeprazole Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 AMINOCAPROIC ACID ACTION PATHWAY%PATHWHIZ%PW000308 Aminocaproic Acid Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 ETODOLAC ACTION PATHWAY%PATHWHIZ%PW000129 Etodolac Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 PROTEIN SYNTHESIS: PROLINE%PATHWHIZ%PW113695 Protein Synthesis: Proline 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 107508 22121 65019 27050 27370 OXYBUPROCAINE ACTION PATHWAY%SMPDB%SMP0000400 Oxybuprocaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 VERAPAMIL ACTION PATHWAY%SMPDB%SMP0000375 Verapamil Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 TYROSINE HYDROXYLASE DEFICIENCY%SMPDB%SMP0000497 Tyrosine Hydroxylase Deficiency 21823 18948 13195 SUCRASE-ISOMALTASE DEFICIENCY%PATHWHIZ%PW122101 Sucrase-Isomaltase Deficiency 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 ORNITHINE AMINOTRANSFERASE DEFICIENCY (OAT DEFICIENCY)%SMPDB%SMP0000363 Ornithine Aminotransferase Deficiency (OAT Deficiency) 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 CXCR4 SIGNALING PATHWAY%SMPDB%SMP0064625 CXCR4 Signaling Pathway 14688 19229 12927 18705 18803 20315 12767 14677 14699 26413 110157 15461 18033 18035 12928 26395 26417 19303 14682 14083 ARGININE: GLYCINE AMIDINOTRANSFERASE DEFICIENCY (AGAT DEFICIENCY)%PATHWHIZ%PW000084 Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency) 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 SHORT-CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (SCAD DEFICIENCY)%PATHWHIZ%PW000108 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency) 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 MUCOPOLYSACCHARIDOSIS VII. SLY SYNDROME%SMPDB%SMP0120839 Mucopolysaccharidosis VII. Sly Syndrome 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 SPIRAPRIL METABOLISM PATHWAY%SMPDB%SMP0000598 Spirapril Metabolism Pathway 11421 FORASARTAN ACTION PATHWAY%PATHWHIZ%PW000280 Forasartan Action Pathway 11607 100038824 11606 11421 DICOUMAROL ACTION PATHWAY%PATHWHIZ%PW000632 Dicoumarol Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 CITALOPRAM ACTION PATHWAY%PATHWHIZ%PW000426 Citalopram Action Pathway 20266 11931 15550 11932 11549 107141 17161 109731 18549 11933 20264 11928 98660 13113 56808 12295 56448 11761 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 TRIPELENNAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057587 Tripelennamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 THENYLDIAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062624 Thenyldiamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 2-HYDROXYGLUTRIC ACIDURIA (D AND L FORM)%SMPDB%SMP0000136 2-Hydroxyglutric Aciduria (D and L Form) 76282 229363 69719 14719 231327 97541 216456 54342 14415 14630 268860 67417 56174 212647 14629 14661 14583 14854 14782 214579 227231 14645 WOLMAN DISEASE%PATHWHIZ%PW000487 Wolman Disease 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 FRUCTOSE INTOLERANCE, HEREDITARY%PATHWHIZ%PW121913 Fructose Intolerance, Hereditary 18642 14120 21991 15275 230163 11676 LIDOCAINE (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000381 Lidocaine (Antiarrhythmic) Action Pathway 20648 11931 11932 243764 11933 11938 13077 13114 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 OXPRENOLOL ACTION PATHWAY%PATHWHIZ%PW000372 Oxprenolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 BLUE DIAPER SYNDROME%SMPDB%SMP0000583 Blue Diaper Syndrome 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 CONGENITAL BILE ACID SYNTHESIS DEFECT TYPE II%PATHWHIZ%PW000192 Congenital Bile Acid Synthesis Defect Type II 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 CANDESARTAN ACTION PATHWAY%SMPDB%SMP0000158 Candesartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 LACTIC ACIDEMIA%PATHWHIZ%PW000114 Lactic Acidemia 76282 11611 55951 18563 224805 TNF STRESS RELATED SIGNALING%PATHWHIZ%PW064784 TNF Stress Related Signaling 19766 21353 12366 26397 12905 71609 22030 21926 26412 100040260 26399 26419 26398 12675 26416 26401 16476 18033 26400 18035 16151 16150 TRIAMTERENE ACTION PATHWAY%SMPDB%SMP0000132 Triamterene Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 POLYTHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000326 Polythiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 PHYTANIC ACID PEROXISOMAL OXIDATION%PATHWHIZ%PW000041 Phytanic Acid Peroxisomal Oxidation 16922 11671 26874 11666 26458 56794 LEPIRUDIN ACTION PATHWAY%SMPDB%SMP0000278 Lepirudin Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 PHOSPHOLIPASE C SIGNALING PATHWAY%PATHWHIZ%PW109280 Phospholipase C Signaling Pathway 18750 18795 18803 11651 104709 MUCOPOLYSACCHARIDOSIS VII. SLY SYNDROME%SMPDB%SMP0000556 Mucopolysaccharidosis VII. Sly Syndrome 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 CYSTINURIA%PATHWHIZ%PW000700 Cystinuria 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 MITOCHONDRIAL BETA-OXIDATION OF LONG CHAIN SATURATED FATTY ACIDS%SMPDB%SMP0000482 Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids 15107 52538 93747 231086 97212 11363 14081 57279 12894 12896 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW088427 Inositol Phosphate Metabolism 76500 228550 71207 69718 327655 16329 71780 55980 269180 2-METHYL-3-HYDROXYBUTYRYL-COA DEHYDROGENASE DEFICIENCY%PATHWHIZ%PW000061 2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 GLUCONEOGENESIS%PATHWHIZ%PW088242 Gluconeogenesis 18563 55951 12183 21991 100043349 14377 13806 230163 56012 319625 20526 67863 14751 14121 211347 18648 72157 18534 PYRIDOXINE DEPENDENCY WITH SEIZURES%SMPDB%SMP0000571 Pyridoxine Dependency with Seizures 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 PYRROBUTAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062887 Pyrrobutamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 OXYCODONE ACTION PATHWAY%SMPDB%SMP0000409 Oxycodone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 DOXYCYCLINE ACTION PATHWAY%PATHWHIZ%PW000359 Doxycycline Action Pathway ACEBUTOLOL ACTION PATHWAY%SMPDB%SMP0000296 Acebutolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 CARBINOXAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058797 Carbinoxamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 AMIKACIN ACTION PATHWAY%SMPDB%SMP0000253 Amikacin Action Pathway NICOTINE ACTION PATHWAY%SMPDB%SMP0000431 Nicotine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 13087 11928 394433 13088 98660 394434 110834 56808 12295 14262 11761 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 HEREDITARY COPROPORPHYRIA (HCP)%SMPDB%SMP0000342 Hereditary Coproporphyria (HCP) 22275 19044 15288 70383 22276 12892 15368 67634 17025 217721 14151 226139 109778 110006 11655 GLYCOGEN STORAGE DISEASE TYPE 1A (GSD1A) OR VON GIERKE DISEASE%SMPDB%SMP0120488 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 GLOBOID CELL LEUKODYSTROPHY%PATHWHIZ%PW000202 Globoid Cell Leukodystrophy 12091 11605 14420 268656 208449 14466 22239 66190 11883 22234 50877 20773 70750 20397 19012 56632 56386 433323 53897 223753 238011 70059 171168 LEVOBUPIVACAINE ACTION PATHWAY%PATHWHIZ%PW000403 Levobupivacaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 HISTIDINE METABOLISM%SMPDB%SMP0000044 Histidine Metabolism 14317 11670 17161 76507 15186 243537 140483 66054 67383 70791 71974 15109 11669 15115 71761 107239 338403 PROTEIN SYNTHESIS: ISOLEUCINE%SMPDB%SMP0111872 Protein Synthesis: Isoleucine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 105148 27370 MALATE-ASPARTATE SHUTTLE%PATHWHIZ%PW000030 Malate-Aspartate Shuttle 14719 78830 17448 67863 UMP SYNTHASE DEFICIENCY (OROTIC ACIDURIA)%SMPDB%SMP0000219 UMP Synthase Deficiency (Orotic Aciduria) 110074 69719 54369 320685 76952 76025 14544 68556 20135 76654 72269 22169 56248 72962 21877 16434 382985 64705 22171 99586 51797 103149 56749 SARCOSINE ONCOMETABOLITE PATHWAY%SMPDB%SMP0002313 Sarcosine Oncometabolite Pathway 238505 108645 74129 110695 232087 14711 20425 12116 192166 218865 108037 68682 100434 PROCAINAMIDE (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000377 Procainamide (Antiarrhythmic) Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 BISOPROLOL ACTION PATHWAY%SMPDB%SMP0000300 Bisoprolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 COCAINE ACTION PATHWAY%SMPDB%SMP0000395 Cocaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 DIPHENHYDRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058785 Diphenhydramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 LECTIN-INDUCED COMPLEMENT PATHWAY%SMPDB%SMP0063898 Lectin-Induced Complement Pathway 109828 625018 12263 230558 17195 12279 17175 15139 12266 12274 FATTY ACID BIOSYNTHESIS%SMPDB%SMP0000456 Fatty Acid Biosynthesis 14104 107476 CAPECITABINE ACTION PATHWAY%PATHWHIZ%PW000256 Capecitabine Action Pathway 434203 104158 72269 72962 22171 L-ARGININE:GLYCINE AMIDINOTRANSFERASE DEFICIENCY%PATHWHIZ%PW000483 L-Arginine:Glycine Amidinotransferase Deficiency 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 PROTEIN SYNTHESIS: ARGININE%SMPDB%SMP0111853 Protein Synthesis: Arginine 20115 104458 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 BETA-ALANINE METABOLISM%SMPDB%SMP0000007 beta-Alanine Metabolism 14415 268860 104776 11669 64705 99586 11754 103149 338403 TENIPOSIDE ACTION PATHWAY%SMPDB%SMP0000443 Teniposide Action Pathway 17523 13114 21973 TRANSFER OF ACETYL GROUPS INTO MITOCHONDRIA%SMPDB%SMP0000466 Transfer of Acetyl Groups into Mitochondria 17449 17436 104112 55951 18563 68263 67863 18597 CLOPIDOGREL METABOLISM PATHWAY%PATHWHIZ%PW000586 Clopidogrel Metabolism Pathway 107141 18979 70839 13077 13114 13088 18671 CLOMOCYCLINE ACTION PATHWAY%SMPDB%SMP0000262 Clomocycline Action Pathway GLICLAZIDE ACTION PATHWAY%SMPDB%SMP0000461 Gliclazide Action Pathway 20927 16334 12286 20526 56808 12295 GLYCEROL METABOLISM%SMPDB%SMP0121309 Glycerol Metabolism 4-HYDROXYBUTYRIC ACIDURIA SUCCINIC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000243 4-Hydroxybutyric Aciduria Succinic Semialdehyde Dehydrogenase Deficiency 76282 229363 69719 14719 231327 97541 216456 54342 14415 14630 268860 67417 56174 212647 14629 14661 14583 14854 14782 214579 227231 14645 ALENDRONATE ACTION PATHWAY%PATHWHIZ%PW000137 Alendronate Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 LABETALOL ACTION PATHWAY%PATHWHIZ%PW000389 Labetalol Action Pathway 20648 11931 11932 11549 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 LONG-CHAIN-3-HYDROXYACYL-COA DEHYDROGENASE DEFICIENCY (LCHAD)%PATHWHIZ%PW000520 Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (LCHAD) 15108 52538 93747 26922 231086 97212 19063 THONZYLAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059696 Thonzylamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 BETA-UREIDOPROPIONASE DEFICIENCY%PATHWHIZ%PW000187 beta-Ureidopropionase Deficiency 110074 69719 54369 320685 76952 76025 14544 68556 20135 76654 72269 22169 56248 72962 21877 16434 382985 64705 22171 99586 51797 103149 56749 FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS%SMPDB%SMP0000358 Fc Epsilon Receptor I Signaling in Mast Cells 18750 16331 18803 14125 16822 16163 16191 16189 16653 20963 19353 228026 18783 14784 18706 17096 18176 16797 12981 14127 57257 26419 14126 26398 110157 26416 15461 11651 18708 26400 14360 26395 26396 26397 26413 12229 21926 26399 20662 14389 DOXEPIN H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060816 Doxepin H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PROPIOMAZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW063580 Propiomazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 STEROIDOGENESIS%SMPDB%SMP0000130 Steroidogenesis 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 GASTRIC ACID PRODUCTION%SMPDB%SMP0000589 Gastric Acid Production 20608 12346 15466 11944 11945 20604 14459 12426 12671 FLECAINIDE ACTION PATHWAY%SMPDB%SMP0000331 Flecainide Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 S-ADENOSYLHOMOCYSTEINE (SAH) HYDROLASE DEFICIENCY%PATHWHIZ%PW000102 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 GOUT OR KELLEY-SEEGMILLER SYNDROME%SMPDB%SMP0000365 Gout or Kelley-Seegmiller Syndrome 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW064563 Pentose Phosphate Pathway 230163 14751 18642 19895 67763 71336 14120 100198 21351 66646 110208 232449 83553 THE ONCOGENIC ACTION OF L-2-HYDROXYGLUTARATE IN HYDROXYGLUTARIC ACIDURIA%PATHWHIZ%PW002451 The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria 55951 217666 216456 269951 66945 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 15926 170718 11428 18597 15929 78920 67680 66052 12974 14661 PENTOSE PHOSPHATE PATHWAY%SMPDB%SMP0087400 Pentose Phosphate Pathway 74419 66171 56421 14121 14751 14381 110639 19895 72157 71336 21351 66646 232449 SUCCINATE SIGNALLING DURING INFLAMMATION%PATHWHIZ%PW122149 Succinate Signalling During Inflammation 18127 18750 18795 12912 18033 26413 16151 16150 26417 METHIONINE METABOLISM%SMPDB%SMP0000033 Methionine Metabolism 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 PANITUMUMAB ACTION PATHWAY%SMPDB%SMP0000475 Panitumumab Action Pathway 13649 THIAZINAMIUM H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061692 Thiazinamium H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 MULTIPLE CARBOXYLASE DEFICIENCY, NEONATAL OR EARLY ONSET FORM%SMPDB%SMP0000564 Multiple Carboxylase Deficiency, Neonatal or Early Onset Form 69019 110948 100705 26363 LANSOPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000590 Lansoprazole Metabolism Pathway 11944 11945 NETILMICIN ACTION PATHWAY%SMPDB%SMP0000257 Netilmicin Action Pathway HYPOACETYLASPARTIA%PATHWHIZ%PW000094 Hypoacetylaspartia 27053 69719 11898 109900 14415 268860 11565 14204 11484 70503 70223 226414 11564 66514 ISOVALERIC ACIDURIA%PATHWHIZ%PW000091 Isovaleric Aciduria 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 11-BETA-HYDROXYLASE DEFICIENCY (CYP11B1)%SMPDB%SMP0000575 11-beta-Hydroxylase Deficiency (CYP11B1) 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 DOBUTAMINE ACTION PATHWAY%PATHWHIZ%PW000639 Dobutamine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 NABUMETONE ACTION PATHWAY%SMPDB%SMP0000114 Nabumetone Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 3-PHOSPHOGLYCERATE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000721 3-Phosphoglycerate Dehydrogenase Deficiency 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 ANTRAFENINE ACTION PATHWAY%SMPDB%SMP0000693 Antrafenine Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 TAURINE AND HYPOTAURINE METABOLISM%SMPDB%SMP0000021 Taurine and Hypotaurine Metabolism 71522 14415 211488 246277 12583 SMITH-LEMLI-OPITZ SYNDROME (SLOS)%PATHWHIZ%PW000095 Smith-Lemli-Opitz Syndrome (SLOS) 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 CONGENITAL BILE ACID SYNTHESIS DEFECT TYPE III%PATHWHIZ%PW000193 Congenital Bile Acid Synthesis Defect Type III 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 DIPYRIDAMOLE (ANTIPLATELET) ACTION PATHWAY%SMPDB%SMP0000264 Dipyridamole (Antiplatelet) Action Pathway 238871 HYPERORNITHINEMIA-HYPERAMMONEMIA-HOMOCITRULLINURIA [HHH-SYNDROME]%PATHWHIZ%PW000482 Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome] 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 GEFITINIB ACTION PATHWAY%SMPDB%SMP0000473 Gefitinib Action Pathway 13649 THIOGUANINE ACTION PATHWAY%PATHWHIZ%PW000429 Thioguanine Action Pathway 63959 15452 19353 75456 27416 239273 11564 16434 11486 23984 67054 67979 11636 229363 210044 13340 14450 269346 54369 22017 76952 11534 238871 53893 231327 11761 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 114304 PHENBENZAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060645 Phenbenzamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PRILOCAINE ACTION PATHWAY%PATHWHIZ%PW000407 Prilocaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 NITRENDIPINE ACTION PATHWAY%SMPDB%SMP0000382 Nitrendipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 RIBOSE-5-PHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW122064 Ribose-5-phosphate Isomerase Deficiency 14381 18641 19895 71336 21351 21881 11674 19139 14121 14751 QUINIDINE ACTION PATHWAY%SMPDB%SMP0000323 Quinidine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 PHENINDIONE ACTION PATHWAY%SMPDB%SMP0000655 Phenindione Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 TICLOPIDINE METABOLISM PATHWAY%SMPDB%SMP0000611 Ticlopidine Metabolism Pathway 70839 BTG FAMILY PROTEINS AND CELL CYCLE REGULATION%SMPDB%SMP0063773 BTG Family Proteins and Cell Cycle Regulation 19645 15469 27221 18049 15417 12226 14164 12227 12443 22059 TRANEXAMIC ACID ACTION PATHWAY%PATHWHIZ%PW000309 Tranexamic Acid Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 GLIBENCLAMIDE ACTION PATHWAY%SMPDB%SMP0000460 Glibenclamide Action Pathway 20927 16334 12286 20526 56808 12295 ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM%SMPDB%SMP0063778 Ion Channels and Their Functional Role in Vascular Endothelium 63873 60613 226922 26946 60596 16536 110862 271639 54195 18127 234889 19091 19092 22065 22066 DOXEPIN METABOLISM PATHWAY%PATHWHIZ%PW000617 Doxepin Metabolism Pathway 107141 13077 13114 56448 TELMISARTAN ACTION PATHWAY%PATHWHIZ%PW000284 Telmisartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 ESMOLOL ACTION PATHWAY%SMPDB%SMP0000301 Esmolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY%SMPDB%SMP0000210 Purine Nucleoside Phosphorylase Deficiency 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 LAMIVUDINE METABOLISM PATHWAY%PATHWHIZ%PW000625 Lamivudine Metabolism Pathway 13178 13026 20887 18102 50773 26357 20519 212862 18671 17250 66588 76408 20517 12780 18655 68671 20518 239273 VENLAFAXINE METABOLISM PATHWAY%PATHWHIZ%PW000612 Venlafaxine Metabolism Pathway 107141 20538 13114 56448 15567 18671 GALACTOSEMIA II (GALK)%SMPDB%SMP0000495 Galactosemia II (GALK) 72157 74246 67883 14430 216558 22235 103988 14635 ROSIGLITAZONE METABOLISM PATHWAY%PATHWHIZ%PW000629 Rosiglitazone Metabolism Pathway 72303 EPLERENONE ACTION PATHWAY%SMPDB%SMP0000135 Eplerenone Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 ETOPOSIDE METABOLISM PATHWAY%PATHWHIZ%PW000577 Etoposide Metabolism Pathway 13114 21974 71853 69191 18671 67838 12304 394436 19035 64136 12282 76408 67397 14828 19224 17523 19225 21973 OMEPRAZOLE METABOLISM PATHWAY%SMPDB%SMP0000613 Omeprazole Metabolism Pathway 11944 11945 SUCRASE-ISOMALTASE DEFICIENCY%PATHWHIZ%PW121877 Sucrase-Isomaltase Deficiency 110006 22239 15275 14751 ARBUTAMINE ACTION PATHWAY%SMPDB%SMP0000664 Arbutamine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 METHADYL ACETATE ACTION PATHWAY%PATHWHIZ%PW000655 Methadyl Acetate Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 MAPLE SYRUP URINE DISEASE%PATHWHIZ%PW000064 Maple Syrup Urine Disease 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 HOMOCARNOSINOSIS%SMPDB%SMP0000385 Homocarnosinosis 76282 229363 69719 14719 231327 97541 216456 54342 14415 14630 268860 67417 56174 212647 14629 14661 14583 14854 14782 214579 227231 14645 ARSENATE DETOXIFICATION%PATHWHIZ%PW122396 Arsenate Detoxification 18950 11832 64008 14873 57344 20528 20525 TYROSINEMIA TYPE 3 (TYRO3)%PATHWHIZ%PW000121 Tyrosinemia Type 3 (TYRO3) 107271 14204 14718 234724 14085 15445 14874 23874 66590 15233 18478 HISTAMINE H1 RECEPTOR ACTIVATION%SMPDB%SMP0063452 Histamine H1 Receptor Activation 14688 18795 18751 18033 16438 15465 14702 14682 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW088275 Inositol Phosphate Metabolism 228550 327655 16329 71780 55980 234515 217837 17330 56409 27399 PROTEIN SYNTHESIS: SERINE%PATHWHIZ%PW120517 Protein Synthesis: Serine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 20226 LYSOPHOSPHATIDIC ACID LPA2 SIGNALLING%SMPDB%SMP0063753 Lysophosphatidic Acid LPA2 Signalling 14688 18795 11651 19877 432530 20807 16438 53978 14702 BILE ACID INDIRECT SIGNALLING PATHWAY%SMPDB%SMP0086851 Bile Acid Indirect Signalling Pathway 20186 14170 83379 14186 14183 14184 20494 14182 GLYCOGENOSIS, TYPE VII. TARUI DISEASE%SMPDB%SMP0120596 Glycogenosis, Type VII. Tarui Disease 18663 68401 12183 21991 15275 230163 13806 319625 56421 14751 14447 18746 239606 18648 PANCREAS FUNCTION - ALPHA CELL%PATHWHIZ%PW122296 Pancreas Function - Alpha Cell 20648 20927 20271 14526 20650 12286 20526 56808 20649 12295 FLUNARIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0061047 Flunarizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 CARPROFEN ACTION PATHWAY%SMPDB%SMP0000694 Carprofen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 PHENPROCOUMON ACTION PATHWAY%PATHWHIZ%PW000314 Phenprocoumon Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 FRUCTOSURIA%SMPDB%SMP0000561 Fructosuria 234730 75454 22122 21991 75540 331026 15275 230163 11674 14121 18641 20322 11677 16548 218138 29858 18639 110119 BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS%PATHWHIZ%PW000161 Beta Oxidation of Very Long Chain Fatty Acids 69129 26874 14081 57279 11666 74114 12908 12896 72129 56273 INTRACELLULAR SIGNALLING THROUGH PROSTACYCLIN RECEPTOR AND PROSTACYCLIN%SMPDB%SMP0000354 Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin 14688 210044 18749 19222 14699 17897 107589 CHLORPHENAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW057579 Chlorphenamine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 LYSINE DEGRADATION%PATHWHIZ%PW000029 Lysine Degradation 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 TOLL-LIKE RECEPTOR PATHWAY 2%SMPDB%SMP0069593 Toll-Like Receptor Pathway 2 26940 81897 53791 21899 66724 21897 170744 26409 26419 26398 12675 12475 117149 26416 17087 26401 21898 22034 18033 17874 18035 16151 16150 19697 54473 170743 16179 66513 142980 24088 68652 GUANIDINOACETATE METHYLTRANSFERASE DEFICIENCY (GAMT DEFICIENCY)%SMPDB%SMP0000188 Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency) 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 IRINOTECAN METABOLISM PATHWAY%SMPDB%SMP0000600 Irinotecan Metabolism Pathway 104158 12038 21969 13114 436059 26357 71853 69191 18671 67838 17250 394434 12304 394436 19035 64136 12282 67397 14828 12780 RIBOSE-5-PHOSPHATE ISOMERASE DEFICIENCY%SMPDB%SMP0120584 Ribose-5-phosphate Isomerase Deficiency 230163 14751 18642 19895 67763 71336 14120 100198 21351 66646 110208 232449 83553 QUIFENADINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061693 Quifenadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 HYDROCODONE ACTION PATHWAY%SMPDB%SMP0000411 Hydrocodone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 PANTOTHENATE AND COA BIOSYNTHESIS%SMPDB%SMP0000027 Pantothenate and CoA Biosynthesis 18605 22361 71743 106564 75735 66812 METOPROLOL ACTION PATHWAY%PATHWHIZ%PW000370 Metoprolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 PENTOSE PHOSPHATE PATHWAY%SMPDB%SMP0000031 Pentose Phosphate Pathway 21881 11674 66171 14751 14121 75456 14381 18641 19895 72157 71336 21351 66646 110208 232449 TRIFUNCTIONAL PROTEIN DEFICIENCY%SMPDB%SMP0000545 Trifunctional Protein Deficiency 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 MOLYBDENUM COFACTOR DEFICIENCY%SMPDB%SMP0000203 Molybdenum Cofactor Deficiency 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 SOTALOL ACTION PATHWAY%SMPDB%SMP0000660 Sotalol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 NON-KETOTIC HYPERGLYCINEMIA%PATHWHIZ%PW000209 Non-Ketotic Hyperglycinemia 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 MOEXIPRIL ACTION PATHWAY%SMPDB%SMP0000151 Moexipril Action Pathway 100038824 11606 11421 17-ALPHA-HYDROXYLASE DEFICIENCY (CYP17)%PATHWHIZ%PW000542 17-alpha-Hydroxylase Deficiency (CYP17) 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 LEVOCETIRIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060053 Levocetirizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 TEMELASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW063837 Temelastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 INTRACELLULAR SIGNALLING THROUGH ADENOSINE RECEPTOR A2A AND ADENOSINE%SMPDB%SMP0000320 Intracellular Signalling Through Adenosine Receptor A2a and Adenosine 14688 18479 109905 11909 19094 18706 26407 18034 54126 109880 26419 11540 12675 223864 13712 56513 15461 76089 11651 26401 16476 18762 18033 26400 18035 16150 26396 18607 18749 12912 14699 26413 20111 26399 12015 ACTIVATION OF PKC THROUGH G PROTEIN-COUPLED RECEPTOR%PATHWHIZ%PW000726 Activation of PKC Through G Protein-Coupled Receptor 18750 18795 16438 14682 HAWKINSINURIA%PATHWHIZ%PW000181 Hawkinsinuria 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 FOLATE MALABSORPTION, HEREDITARY%PATHWHIZ%PW000701 Folate Malabsorption, Hereditary 107747 14317 13361 17768 100039707 270685 14287 52466 17769 69606 108156 667301 SUFENTANIL ACTION PATHWAY%PATHWHIZ%PW000423 Sufentanil Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 CLOCINIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062788 Clocinizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PROPANOATE METABOLISM%SMPDB%SMP0000016 Propanoate Metabolism 13382 110446 12039 68738 268860 12040 93747 227095 66904 110821 11364 13171 104776 56690 106557 107476 73724 TRICHLORMETHIAZIDE ACTION PATHWAY%SMPDB%SMP0000121 Trichlormethiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 FATTY ACID ELONGATION IN MITOCHONDRIA%SMPDB%SMP0000054 Fatty Acid Elongation in Mitochondria 15108 52538 93747 26922 231086 97212 19063 ALVIMOPAN ACTION PATHWAY%SMPDB%SMP0000685 Alvimopan Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 PROTEIN SYNTHESIS: THREONINE%PATHWHIZ%PW120525 Protein Synthesis: Threonine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 110960 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 SIMVASTATIN ACTION PATHWAY%PATHWHIZ%PW000127 Simvastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 FRUCTOSE-1,6-DIPHOSPHATASE DEFICIENCY%PATHWHIZ%PW121882 Fructose-1,6-diphosphatase Deficiency 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 WARBURG EFFECT%PATHWHIZ%PW088382 Warburg Effect 55951 100043349 13806 56012 18655 20512 18770 66945 67834 66925 56451 209692 20501 11429 14194 13382 235339 21881 68263 170718 15926 11428 78920 14751 14381 17449 18641 18746 67680 66052 12974 19895 14661 14660 15277 21351 PTERINE BIOSYNTHESIS%PATHWHIZ%PW000140 Pterine Biosynthesis 110391 20751 13361 11677 12408 19286 320415 14528 NUCLEOTIDE SUGARS METABOLISM%PATHWHIZ%PW000031 Nucleotide Sugars Metabolism 72157 74246 67883 14430 216558 22235 103988 14635 PYRUVATE DEHYDROGENASE DEFICIENCY (E3)%SMPDB%SMP0000550 Pyruvate Dehydrogenase Deficiency (E3) 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 3-METHYLTHIOFENTANYL ACTION PATHWAY%PATHWHIZ%PW000656 3-Methylthiofentanyl Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 PROTEIN SYNTHESIS: ALANINE%PATHWHIZ%PW120529 Protein Synthesis: Alanine 20115 319195 67248 100043391 100040331 432502 667279 668144 100043755 621100 665189 67281 666899 100042670 629957 100039316 76846 667739 234734 100038875 19921 100038991 267019 100043876 100043000 100043423 16785 100042986 20044 100040298 20088 100042740 56040 667618 57294 666669 100040970 20085 20084 19899 67891 66480 67097 19934 66481 67025 100039924 19941 100042823 14694 100039656 20055 672959 20054 666586 676253 67427 670211 100043527 27207 666487 68193 67186 19989 19951 76808 75617 20103 20102 20068 22121 65019 26961 27050 27370 VINBLASTINE ACTION PATHWAY%SMPDB%SMP0000436 Vinblastine Action Pathway 224814 76408 12575 12780 13114 18671 17250 545486 19765 22143 22059 QUINAPRIL METABOLISM PATHWAY%SMPDB%SMP0000596 Quinapril Metabolism Pathway 11421 CARVEDILOL ACTION PATHWAY%SMPDB%SMP0000367 Carvedilol Action Pathway 20648 11931 11932 11549 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 TRANDOLAPRIL ACTION PATHWAY%SMPDB%SMP0000157 Trandolapril Action Pathway 100038824 11606 11421 BETAHISTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061694 Betahistine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 DEMECLOCYCLINE ACTION PATHWAY%PATHWHIZ%PW000358 Demeclocycline Action Pathway INOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0063630 Inositol Phosphate Metabolism 69718 102954 16332 277360 ESOMEPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000315 Esomeprazole Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 SARCOSINEMIA%SMPDB%SMP0000244 Sarcosinemia 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 LYSINURIC PROTEIN INTOLERANCE (LPI)%SMPDB%SMP0000585 Lysinuric Protein Intolerance (LPI) 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 QUETIAPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062884 Quetiapine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 UBIQUINONE BIOSYNTHESIS%SMPDB%SMP0000065 Ubiquinone Biosynthesis 12850 71883 217707 52064 230027 EPINASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW062142 Epinastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 GLYCOGENOSIS, TYPE IA. VON GIERKE DISEASE%SMPDB%SMP0120864 Glycogenosis, Type IA. Von Gierke Disease 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 XANTHINE DEHYDROGENASE DEFICIENCY (XANTHINURIA)%SMPDB%SMP0000220 Xanthine Dehydrogenase Deficiency (Xanthinuria) 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 GLYCOGENOSIS, TYPE IB%PATHWHIZ%PW122117 Glycogenosis, Type IB 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 GLYCOGENOSIS, TYPE VI. HERS DISEASE%SMPDB%SMP0120838 Glycogenosis, Type VI. Hers Disease 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 AZITHROMYCIN ACTION PATHWAY%PATHWHIZ%PW000345 Azithromycin Action Pathway PYRUVATE DEHYDROGENASE DEFICIENCY (E2)%SMPDB%SMP0000551 Pyruvate Dehydrogenase Deficiency (E2) 66945 55951 18563 67834 56451 66925 209692 20917 11429 13382 14194 235339 68263 170718 18597 15929 78920 17449 67680 66052 12974 TRISALICYLATE-CHOLINE ACTION PATHWAY%PATHWHIZ%PW000680 Trisalicylate-Choline Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 HISTIDINEMIA%PATHWHIZ%PW000113 Histidinemia 14317 11670 17161 76507 15186 243537 140483 66054 67383 70791 71974 15109 11669 15115 71761 107239 338403 CILOSTAZOL ACTION PATHWAY%SMPDB%SMP0000263 Cilostazol Action Pathway 107141 13114 238871 MONOAMINE OXIDASE-A DEFICIENCY (MAO-A)%PATHWHIZ%PW000509 Monoamine Oxidase-A Deficiency (MAO-A) 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 FENETHAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059707 Fenethazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 MITOCHONDRIAL BETA-OXIDATION OF MEDIUM CHAIN SATURATED FATTY ACIDS%PATHWHIZ%PW000172 Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids 15107 52538 93747 231086 97212 117147 57279 11364 ROXITHROMYCIN ACTION PATHWAY%SMPDB%SMP0000251 Roxithromycin Action Pathway SULFATE SULFITE METABOLISM%PATHWHIZ%PW000040 Sulfate Sulfite Metabolism 58250 54200 20887 23827 211389 23972 ANDROSTENEDIONE METABOLISM%SMPDB%SMP0030406 Androstenedione Metabolism 110115 15483 71853 69191 67838 12304 78925 208665 394436 15487 83702 19035 64136 13075 12282 67397 14828 CYCLOPHOSPHAMIDE METABOLISM PATHWAY%PATHWHIZ%PW000580 Cyclophosphamide Metabolism Pathway 11670 107141 11668 14863 13114 13088 13087 72303 THE ONCOGENIC ACTION OF SUCCINATE%PATHWHIZ%PW002360 The Oncogenic Action of Succinate 55951 269951 112407 112406 66945 18563 67834 27376 56451 66925 209692 20917 11429 13382 14194 235339 68263 15926 170718 11428 18597 15929 78920 67680 66052 12974 BEVACIZUMAB ACTION PATHWAY%SMPDB%SMP0000420 Bevacizumab Action Pathway 16542 22339 14254 NEOMYCIN ACTION PATHWAY%SMPDB%SMP0000256 Neomycin Action Pathway MORPHINE METABOLISM PATHWAY%SMPDB%SMP0000622 Morphine Metabolism Pathway 22236 71853 69191 67838 394434 12304 394436 19035 64136 12282 67397 14828 71773 231396 18390 GLYCEROL METABOLISM III (SN-GLYCERO-3-PHOSPHOETHANOLAMINE)%PATHWHIZ%PW000916 Glycerol Metabolism III (sn-Glycero-3-Phosphoethanolamine) BROMODIPHENHYDRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059740 Bromodiphenhydramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 TRANSALDOLASE DEFICIENCY%SMPDB%SMP0120585 Transaldolase Deficiency 230163 14751 18642 19895 67763 71336 14120 100198 21351 66646 110208 232449 83553 KETOPROFEN ACTION PATHWAY%SMPDB%SMP0000085 Ketoprofen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 LIDOCAINE (LOCAL ANAESTHETIC) ACTION PATHWAY%SMPDB%SMP0000398 Lidocaine (Local Anaesthetic) Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 13077 13114 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 PHOSPHATIDYLETHANOLAMINE BIOSYNTHESIS%SMPDB%SMP0029731 Phosphatidylethanolamine Biosynthesis 12660 19210 68671 320951 99712 METHYLMALONIC ACIDURIA%SMPDB%SMP0000200 Methylmalonic Aciduria 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 PROTEIN SYNTHESIS: TYROSINE%PATHWHIZ%PW120527 Protein Synthesis: Tyrosine 20115 319195 67248 107271 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 BETA-KETOTHIOLASE DEFICIENCY%SMPDB%SMP0000173 beta-Ketothiolase Deficiency 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 GLYCOLYSIS%SMPDB%SMP0063478 Glycolysis 18663 68401 12183 21991 15275 230163 13806 319625 56421 14751 14447 18746 239606 18648 LORNOXICAM ACTION PATHWAY%PATHWHIZ%PW000677 Lornoxicam Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 INOSITOL METABOLISM%SMPDB%SMP0000011 Inositol Metabolism 224020 103199 228550 56208 18711 225326 16329 71780 55980 228361 66461 72469 56727 217837 75678 234729 269180 75669 17330 18706 69718 PROPARACAINE ACTION PATHWAY%PATHWHIZ%PW000409 Proparacaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 FLAVONOID BIOSYNTHESIS%SMPDB%SMP0012021 Flavonoid Biosynthesis 71519 ROPIVACAINE ACTION PATHWAY%PATHWHIZ%PW000410 Ropivacaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 XANTHINURIA TYPE II%PATHWHIZ%PW000489 Xanthinuria Type II 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 VALPROIC ACID METABOLISM PATHWAY%SMPDB%SMP0000635 Valproic Acid Metabolism Pathway 15108 22236 231086 97212 13088 13087 66885 117147 74147 56357 PROTEIN SYNTHESIS: ASPARTIC ACID%SMPDB%SMP0111858 Protein Synthesis: Aspartic Acid 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 226414 27050 27370 LACTOSE INTOLERANCE%PATHWHIZ%PW000206 Lactose Intolerance 20537 11931 11932 11933 11928 226413 98660 20526 232975 CILAZAPRIL ACTION PATHWAY%SMPDB%SMP0000147 Cilazapril Action Pathway 100038824 11606 11421 METIPRANOLOL ACTION PATHWAY%PATHWHIZ%PW000644 Metipranolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 FOSPHENYTOIN (ANTIARRHYTHMIC) METABOLISM PATHWAY%SMPDB%SMP0000618 Fosphenytoin (Antiarrhythmic) Metabolism Pathway 20648 20271 20650 20649 LEVOCABASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060224 Levocabastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 TENECTEPLASE ACTION PATHWAY%SMPDB%SMP0000283 Tenecteplase Action Pathway 12842 110135 99571 18791 18815 14161 14068 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 3-HYDROXYISOBUTYRIC ACID DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000521 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 NEVIRAPINE METABOLISM PATHWAY%PATHWHIZ%PW000618 Nevirapine Metabolism Pathway 224814 11668 13114 13088 56448 394434 DEXCHLORPHENIRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0056811 Dexchlorpheniramine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 G-SECRETASE MEDIATED ERBB4 SIGNALLING PATHWAY%PATHWHIZ%PW090995 g-Secretase Mediated ErbB4 Signalling Pathway 13867 18750 11491 19164 13649 100042150 13869 RAC 1 CELL MOTILITY SIGNALING PATHWAY%SMPDB%SMP0063795 Rac 1 Cell Motility Signaling Pathway 18479 19353 76932 329251 12443 19765 18595 18538 12568 12631 57257 11461 12575 12445 17906 16885 12331 26401 18805 83767 107589 D-ARGININE AND D-ORNITHINE METABOLISM%PATHWHIZ%PW000019 D-Arginine and D-Ornithine Metabolism 13142 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW000539 Triosephosphate Isomerase Deficiency 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 HOMOCYSTEINE DEGRADATION%SMPDB%SMP0000455 Homocysteine Degradation 107869 12411 KETOBEMIDONE ACTION PATHWAY%SMPDB%SMP0000690 Ketobemidone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCOLYSIS%PATHWHIZ%PW000146 Glycolysis 12183 14377 100043349 13806 319625 20526 56012 11674 14751 18648 18642 18655 15277 18770 METACHROMATIC LEUKODYSTROPHY (MLD)%SMPDB%SMP0000347 Metachromatic Leukodystrophy (MLD) 12091 11605 14420 268656 208449 14466 22239 66190 11883 22234 50877 20773 70750 20397 19012 56632 56386 433323 53897 223753 238011 70059 171168 GLYCOGENOSIS, TYPE III. CORI DISEASE, DEBRANCHER GLYCOGENOSIS%SMPDB%SMP0120617 Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis 110006 22239 15275 14751 NF-KB SIGNALING PATHWAY%PATHWHIZ%PW064818 NF-kB Signaling Pathway 55984 14082 26409 12675 26401 21898 22034 18033 17874 18035 16151 16150 19697 22190 19766 71609 21926 53859 16177 21937 21938 16179 17979 66513 16175 207565 METHYLHISTIDINE METABOLISM%PATHWHIZ%PW000692 Methylhistidine Metabolism 11461 GLYCINE N-METHYLTRANSFERASE DEFICIENCY%SMPDB%SMP0000222 Glycine N-Methyltransferase Deficiency 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 LONG CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (LCAD)%PATHWHIZ%PW000515 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 DEPTROPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062883 Deptropine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 METHADONE ACTION PATHWAY%PATHWHIZ%PW000414 Methadone Action Pathway 20266 11931 15550 11932 11549 107141 18549 11933 20264 13114 11928 13088 98660 13113 56808 12295 56448 12286 13162 20538 18976 15567 11444 11438 72303 16508 18390 232975 14811 14810 13488 BROMFENAC ACTION PATHWAY%SMPDB%SMP0000102 Bromfenac Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 ROXATIDINE ACETATE ACTION PATHWAY%PATHWHIZ%PW000711 Roxatidine Acetate Action Pathway 20608 12346 15466 11944 11945 20604 14459 12426 12671 WARBURG EFFECT%SMPDB%SMP0087270 Warburg Effect 55951 100043349 13806 56012 66171 18655 20514 67834 18563 56451 20501 20917 11429 13382 14194 18293 230163 20526 27402 68263 21881 170718 15926 18597 11428 78920 14751 15929 17449 14381 18641 18746 67680 66052 12974 14661 19895 CERIVASTATIN ACTION PATHWAY%PATHWHIZ%PW000271 Cerivastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 OXOMEMAZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060682 Oxomemazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW000150 Starch and Sucrose Metabolism 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 PONATINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032598 Ponatinib Inhibition of BCR-ABL 17869 56717 14784 22059 20662 20850 16452 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 ALPHA LINOLENIC ACID AND LINOLEIC ACID METABOLISM%PATHWHIZ%PW000006 Alpha Linolenic Acid and Linoleic Acid Metabolism 83603 68801 56473 76267 OXYMORPHONE ACTION PATHWAY%PATHWHIZ%PW000418 Oxymorphone Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 CARFENTANIL ACTION PATHWAY%SMPDB%SMP0000414 Carfentanil Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GAMMA-GLUTAMYLTRANSFERASE DEFICIENCY%PATHWHIZ%PW000110 gamma-Glutamyltransferase Deficiency 71522 14775 12369 68252 14630 14629 14854 14782 68214 75475 16790 KRABBE DISEASE%PATHWHIZ%PW000502 Krabbe Disease 12091 11605 14420 268656 208449 14466 22239 66190 11883 22234 50877 20773 70750 20397 19012 56632 56386 433323 53897 223753 238011 70059 171168 PORPHYRIN METABOLISM%SMPDB%SMP0000024 Porphyrin Metabolism 22275 19044 15288 70383 22276 12892 15368 67634 17025 217721 14151 226139 109778 110006 11655 ANDROGEN AND ESTROGEN METABOLISM%SMPDB%SMP0000068 Androgen and Estrogen Metabolism 13075 54200 100559 13074 20860 78925 208665 15497 15487 15485 BETAINE METABOLISM%SMPDB%SMP0000123 Betaine Metabolism 238505 110695 232087 18618 12116 269378 218865 108645 BIOTINIDASE DEFICIENCY%SMPDB%SMP0000174 Biotinidase Deficiency 69019 110948 100705 26363 FUROSEMIDE ACTION PATHWAY%PATHWHIZ%PW000337 Furosemide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 DESLORATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060201 Desloratadine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 ENALAPRIL ACTION PATHWAY%SMPDB%SMP0000148 Enalapril Action Pathway 100038824 11606 11421 ERYTHROMYCIN ACTION PATHWAY%SMPDB%SMP0000250 Erythromycin Action Pathway LEVOMETHADYL ACETATE ACTION ACTION PATHWAY%SMPDB%SMP0000677 Levomethadyl Acetate Action Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 PROTEIN SYNTHESIS: CYSTEINE%PATHWHIZ%PW112918 Protein Synthesis: Cysteine 20115 319195 67248 100043391 27267 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 BAFETINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032597 Bafetinib Inhibition of BCR-ABL 17869 56717 14784 22059 20662 20850 16452 12576 18708 12048 12929 12928 12015 14389 27401 12402 17246 PYRUVATE CARBOXYLASE DEFICIENCY%SMPDB%SMP0000350 Pyruvate Carboxylase Deficiency 76282 11611 55951 18563 224805 CETUXIMAB ACTION PATHWAY%SMPDB%SMP0000474 Cetuximab Action Pathway 13649 FELODIPINE ACTION PATHWAY%PATHWHIZ%PW000392 Felodipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 MYCOPHENOLIC ACID METABOLISM PATHWAY%PATHWHIZ%PW000628 Mycophenolic Acid Metabolism Pathway 100042069 104158 12780 13114 436059 26357 18671 394434 72303 23917 28253 RETINOL METABOLISM%SMPDB%SMP0000074 Retinol Metabolism 11668 13114 13087 13088 71853 69191 67838 12304 394436 19035 64136 12282 67397 14828 28200 67442 63857 235033 241452 13350 20148 79235 19378 622127 13113 77974 216454 17252 19892 245533 13082 DESIPRAMINE ACTION PATHWAY%PATHWHIZ%PW000425 Desipramine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 56448 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 DOPAMINE BETA-HYDROXYLASE DEFICIENCY%SMPDB%SMP0000498 Dopamine beta-Hydroxylase Deficiency 11670 17161 14718 17319 107766 13166 22173 12846 13190 14085 14874 18948 15233 13195 76507 CLOPIDOGREL ACTION PATHWAY%PATHWHIZ%PW000286 Clopidogrel Action Pathway 107141 18979 70839 13077 13114 13088 18671 TETRACYCLINE ACTION PATHWAY%SMPDB%SMP0000294 Tetracycline Action Pathway EPINEPHRINE ACTION PATHWAY%PATHWHIZ%PW000638 Epinephrine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 3-METHYLGLUTACONIC ACIDURIA TYPE IV%SMPDB%SMP0000141 3-Methylglutaconic Aciduria Type IV 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 THYROID HORMONE SYNTHESIS%PATHWHIZ%PW000693 Thyroid Hormone Synthesis 99439 224480 21819 114479 22018 13058 50490 13057 214593 HYDROXYZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058936 Hydroxyzine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0087197 Fructose and Mannose Degradation 234730 75454 22122 75540 21991 230163 54128 76355 320844 14121 18641 20322 16548 11677 18639 110119 INTRACELLULAR SIGNALLING THROUGH ADENOSINE RECEPTOR A2B AND ADENOSINE%SMPDB%SMP0000321 Intracellular Signalling Through Adenosine Receptor A2b and Adenosine 14688 18479 109905 11909 19094 18706 26407 18034 11541 54126 109880 26419 12675 223864 13712 56513 15461 76089 11651 26401 16476 18762 18033 26400 18035 16150 26396 210044 18607 18749 12912 14699 26413 20111 26399 12015 FANCONI-BICKEL SYNDROME%SMPDB%SMP0000572 Fanconi-Bickel Syndrome 12183 14377 100043349 13806 319625 20526 56012 11674 14751 18648 18642 18655 15277 18770 ROSUVASTATIN ACTION PATHWAY%SMPDB%SMP0000092 Rosuvastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 PAROMOMYCIN ACTION PATHWAY%PATHWHIZ%PW000691 Paromomycin Action Pathway PANCREAS FUNCTION - DELTA CELL%PATHWHIZ%PW122406 Pancreas Function - Delta Cell 20927 12286 20604 20526 56808 12295 LEUCINE STIMULATION ON INSULIN SIGNALING%SMPDB%SMP0000682 Leucine Stimulation on Insulin Signaling 384783 56717 16337 16367 16334 64930 22084 13685 13684 11651 30955 104709 20539 HYPERPHENYLALANINEMIA DUE TO GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE DEFICIENCY%SMPDB%SMP0000487 Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency 110391 20751 13361 11677 12408 19286 320415 14528 SUCCINYL COA: 3-KETOACID COA TRANSFERASE DEFICIENCY%SMPDB%SMP0000569 Succinyl CoA: 3-Ketoacid CoA Transferase Deficiency 110446 71911 15356 67041 BOPINDOLOL ACTION PATHWAY%SMPDB%SMP0000657 Bopindolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 CEREBROTENDINOUS XANTHOMATOSIS (CTX)%PATHWHIZ%PW000196 Cerebrotendinous Xanthomatosis (CTX) 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 SUCCINATE SIGNALLING%PATHWHIZ%PW084312 Succinate Signalling 15251 16176 21898 64384 216799 320452 GLYCOGENOSIS, TYPE IC%PATHWHIZ%PW122118 Glycogenosis, Type IC 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 ARTEMETHER METABOLISM PATHWAY%PATHWHIZ%PW000627 Artemether Metabolism Pathway 13114 394434 3-METHYLGLUTACONIC ACIDURIA TYPE III%SMPDB%SMP0000140 3-Methylglutaconic Aciduria Type III 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY%PATHWHIZ%PW000117 Pyruvate Dehydrogenase Complex Deficiency 17436 76238 18563 13382 235339 68263 18597 110446 17449 11677 60525 14651 109801 52815 11669 18770 18534 16828 107476 66204 74156 REMIFENTANIL ACTION PATHWAY%PATHWHIZ%PW000422 Remifentanil Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 IRBESARTAN ACTION PATHWAY%PATHWHIZ%PW000281 Irbesartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 TRANDOLAPRIL METABOLISM PATHWAY%PATHWHIZ%PW000575 Trandolapril Metabolism Pathway 11421 NALBUPHINE ACTION PATHWAY%SMPDB%SMP0000691 Nalbuphine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 18387 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 EXCITATORY NEURAL SIGNALLING THROUGH 5-HTR 4 AND SEROTONIN%PATHWHIZ%PW000441 Excitatory Neural Signalling Through 5-HTR 4 and Serotonin 14688 18749 19045 12912 14699 15562 ESTRONE METABOLISM%SMPDB%SMP0030880 Estrone Metabolism 71853 69191 12846 67838 12304 394436 19035 15485 64136 12282 13076 67397 14828 20860 MEDIUM CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (MCAD)%PATHWHIZ%PW000518 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD) 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 BILASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061119 Bilastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 THENALIDINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062894 Thenalidine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 TRASTUZUMAB ACTION PATHWAY%SMPDB%SMP0000476 Trastuzumab Action Pathway 13649 NIMODIPINE ACTION PATHWAY%PATHWHIZ%PW000395 Nimodipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 GNRH SIGNALING PATHWAY%PATHWHIZ%PW064816 GnRH Signaling Pathway 18750 18795 13649 18751 18747 14784 26419 110157 13712 26416 15461 60595 26401 16476 18805 14714 14715 14672 432530 26400 12288 17390 26395 26405 12322 17387 14308 16866 56808 20779 12295 11911 13653 12640 15200 12289 54652 12292 26397 26413 20662 16438 TENOXICAM ACTION PATHWAY%SMPDB%SMP0000706 Tenoxicam Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 NISOLDIPINE ACTION PATHWAY%PATHWHIZ%PW000396 Nisoldipine Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 FLUOROURACIL ACTION PATHWAY%SMPDB%SMP0000470 Fluorouracil Action Pathway 22171 INOSITOL METABOLISM%PATHWHIZ%PW088354 Inositol Metabolism 228550 83493 56208 225326 71780 228361 55980 66461 217837 56727 75678 269180 234729 23827 75669 17330 12462 170835 69718 18799 VERY-LONG-CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (VLCAD)%SMPDB%SMP0000540 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD) 11409 52538 231086 97212 11363 14081 66885 11370 12894 12896 270076 110446 93747 11364 ESCITALOPRAM ACTION PATHWAY%PATHWHIZ%PW000427 Escitalopram Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 TOLL-LIKE RECEPTOR PATHWAY 1%PATHWHIZ%PW064909 Toll-Like Receptor Pathway 1 26940 81897 26409 26419 14281 26398 12675 12475 117149 13712 26416 17087 26401 16476 21898 22034 18033 17874 18035 16151 19013 16150 19106 19697 26397 26399 54473 170743 16179 66513 142980 24088 68652 CARDIOLIPIN BIOSYNTHESIS%SMPDB%SMP0020986 Cardiolipin Biosynthesis 110911 66586 52123 66461 14732 74451 14555 T CELL RECEPTOR SIGNALING PATHWAY%SMPDB%SMP0066977 T Cell Receptor Signaling Pathway 18750 18803 18751 19353 16818 14784 18706 16797 20416 26419 26398 14281 110157 13712 15461 26401 16476 18708 18033 18035 14360 26395 19055 12501 19697 26417 22637 320139 19419 22190 12502 12503 19056 12500 18021 73181 18018 18019 20662 19057 640703 22324 30955 MERCAPTOPURINE METABOLISM PATHWAY%SMPDB%SMP0000609 Mercaptopurine Metabolism Pathway 63959 229363 13340 269346 22017 15452 11534 231327 11761 19353 23917 22436 27416 239273 114304 FELODIPINE METABOLISM PATHWAY%SMPDB%SMP0000619 Felodipine Metabolism Pathway 12288 56808 12295 ION CHANNEL AND PHORBAL ESTERS SIGNALING PATHWAY%SMPDB%SMP0090032 Ion Channel and Phorbal Esters Signaling Pathway 19229 18750 18803 18751 18442 MYOADENYLATE DEAMINASE DEFICIENCY%PATHWHIZ%PW000513 Myoadenylate Deaminase Deficiency 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 HOMOCYSTINURIA-MEGALOBLASTIC ANEMIA DUE TO DEFECT IN COBALAMIN METABOLISM, CBLG COMPLEMENTATION TYPE%SMPDB%SMP0000570 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type 12411 108645 76467 66902 107869 13433 14204 320183 216443 232087 20425 17769 12116 20810 218865 MEQUITAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059720 Mequitazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 BUPIVACAINE ACTION PATHWAY%SMPDB%SMP0000393 Bupivacaine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 MNGIE (MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY)%PATHWHIZ%PW000190 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) 110074 69719 54369 320685 76952 76025 14544 68556 20135 76654 72269 22169 56248 72962 21877 16434 382985 64705 22171 99586 51797 103149 56749 NITRIC OXIDE SIGNALING PATHWAY%SMPDB%SMP0063777 Nitric Oxide Signaling Pathway 18750 640703 18749 18125 11669 16438 22436 19055 14811 14810 13385 METHAPYRILENE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058741 Methapyrilene H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 WARBURG EFFECT%SMPDB%SMP0087420 Warburg Effect 55951 229699 74419 100043349 13806 56012 20525 66171 18655 66945 18563 67834 56451 66925 209692 20917 15275 14194 13382 235339 68263 15926 56421 18597 11428 78920 14751 14381 17449 18746 67680 66052 12974 19895 14661 14660 21351 110208 TALASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058511 Talastine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 HYPOPHOSPHATASIA%SMPDB%SMP0000503 Hypophosphatasia 57028 216134 11647 103711 11761 PRAVASTATIN ACTION PATHWAY%SMPDB%SMP0000089 Pravastatin Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 SUCCINIC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000567 Succinic Semialdehyde Dehydrogenase Deficiency 76282 229363 69719 14719 231327 97541 216456 54342 14415 14630 268860 67417 56174 212647 14629 14661 14583 14854 14782 214579 227231 14645 JOUBERT SYNDROME%SMPDB%SMP0000582 Joubert Syndrome 18718 224020 103199 18795 16331 13649 56208 52858 18711 18704 225326 13866 18707 18720 228361 234515 234729 75669 18708 19211 64436 104015 ADRENAL HYPERPLASIA TYPE 5 OR CONGENITAL ADRENAL HYPERPLASIA DUE TO 17 ALPHA-HYDROXYLASE DEFICIENCY%SMPDB%SMP0000372 Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 FLUOXETINE ACTION PATHWAY%PATHWHIZ%PW000428 Fluoxetine Action Pathway 20266 11931 15550 11932 11549 107141 18549 11933 20264 13114 11928 98660 56808 12295 56448 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 APPARENT MINERALOCORTICOID EXCESS SYNDROME%SMPDB%SMP0000717 Apparent Mineralocorticoid Excess Syndrome 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 CYSTINOSIS, OCULAR NONNEPHROPATHIC%PATHWHIZ%PW000699 Cystinosis, Ocular Nonnephropathic 107869 14630 14718 14629 12583 83429 27267 246221 16828 BILE ACID DIRECT SIGNALLING PATHWAY (1)%PATHWHIZ%PW087627 Bile Acid Direct Signalling Pathway (1) 20186 28250 239273 227289 20494 OXIDATION OF BRANCHED-CHAIN FATTY ACIDS%SMPDB%SMP0000030 Oxidation of Branched-Chain Fatty Acids 16922 26874 14081 57279 11666 11669 12908 56794 12896 72129 56273 ARDEPARIN ACTION PATHWAY%SMPDB%SMP0000275 Ardeparin Action Pathway 12842 110135 99571 18791 18815 14161 14068 11905 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 CHLORCYCLIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058931 Chlorcyclizine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 FENOPROFEN ACTION PATHWAY%SMPDB%SMP0000696 Fenoprofen Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 NEURON FUNCTION%SMPDB%SMP0000224 Neuron Function 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCOGEN STORAGE DISEASE TYPE 1A (GSD1A) OR VON GIERKE DISEASE%PATHWHIZ%PW121967 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease 269614 55951 17448 21991 100043349 14377 13806 56012 319625 11674 67863 14121 14751 15277 18534 GLUT-1 DEFICIENCY SYNDROME%SMPDB%SMP0000580 GLUT-1 Deficiency Syndrome 18103 14430 216558 76025 14377 66588 16770 22232 20525 14595 ROFECOXIB ACTION PATHWAY%SMPDB%SMP0000087 Rofecoxib Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 DIPHENYLPYRALINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059841 Diphenylpyraline H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 FLUOROURACIL METABOLISM PATHWAY%SMPDB%SMP0000608 Fluorouracil Metabolism Pathway 22171 DIHYDROMORPHINE ACTION PATHWAY%PATHWHIZ%PW000666 Dihydromorphine Action Pathway 20266 11931 15550 11932 11549 18549 11933 20264 11928 98660 56808 12295 12286 13162 20538 18976 15567 11444 11438 16508 18390 232975 14811 14810 13488 GLYCOGENOSIS, TYPE IB%PATHWHIZ%PW121893 Glycogenosis, Type IB 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 GENTAMICIN ACTION PATHWAY%SMPDB%SMP0000254 Gentamicin Action Pathway LESCH-NYHAN SYNDROME (LNS)%SMPDB%SMP0000364 Lesch-Nyhan Syndrome (LNS) 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 SORAFENIB METABOLISM PATHWAY%PATHWHIZ%PW000624 Sorafenib Metabolism Pathway 13114 13088 71853 69191 67838 394434 12304 394436 19035 64136 12282 67397 14828 72303 PRIMARY HYPEROXALURIA II, PH2%SMPDB%SMP0000558 Primary Hyperoxaluria II, PH2 17436 76238 18563 13382 235339 68263 18597 110446 17449 11677 60525 14651 109801 52815 11669 18770 18534 16828 107476 66204 74156 TRITOQUALINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062895 Tritoqualine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 3-METHYLCROTONYL-COA CARBOXYLASE DEFICIENCY TYPE I%SMPDB%SMP0000237 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I 11669 11409 15108 52538 15356 15360 66885 11761 67041 13382 56357 78038 12035 66948 11992 110446 58875 12039 72039 268860 12040 93747 227095 66904 110821 11364 13171 104776 SPHINGOLIPID METABOLISM%SMPDB%SMP0000034 Sphingolipid Metabolism 12091 11605 14420 268656 208449 14466 22239 66190 11883 22234 50877 20773 70750 20397 19012 56632 56386 433323 53897 223753 238011 70059 171168 21-HYDROXYLASE DEFICIENCY (CYP21)%SMPDB%SMP0000576 21-Hydroxylase Deficiency (CYP21) 110115 13070 13074 15492 15484 15483 13079 208665 15497 83702 13072 DIMETHYLGLYCINE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000242 Dimethylglycine Dehydrogenase Deficiency 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 DIMETHYLGLYCINE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000484 Dimethylglycine Dehydrogenase Deficiency 104174 17161 67092 13382 14431 107869 11611 74129 27364 107272 11655 14711 20425 100678 353172 192166 11669 235582 231691 108037 20226 434437 26912 236539 GLYCOLYSIS%PATHWHIZ%PW088336 Glycolysis 18642 15277 21991 14377 100043349 13806 18770 56012 319625 11674 14751 CORTICOTROPIN ACTIVATION OF CORTISOL PRODUCTION%SMPDB%SMP0000310 Corticotropin Activation of Cortisol Production 14688 17200 18749 14699 18976 GLYCOGENOSIS, TYPE IV. AMYLOPECTINOSIS, ANDERSON DISEASE%SMPDB%SMP0120618 Glycogenosis, Type IV. Amylopectinosis, Anderson Disease 110006 22239 15275 14751 IFOSFAMIDE METABOLISM PATHWAY%PATHWHIZ%PW000581 Ifosfamide Metabolism Pathway 11670 11668 13114 13088 13087 72303 ESOMEPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000588 Esomeprazole Metabolism Pathway 11944 11945 NITRIC OXIDE SIGNALING PATHWAY%SMPDB%SMP0108236 Nitric Oxide Signaling Pathway 18750 18749 18125 12313 19055 14811 14810 13385 AHR SIGNAL TRANSDUCTION PATHWAY%PATHWHIZ%PW064763 Ahr Signal Transduction Pathway 11863 11622 15519 EGF SIGNALLING PATHWAY%SMPDB%SMP0120948 EGF Signalling Pathway 18750 18803 18751 20807 20848 14784 100039026 20416 13645 20850 26419 218397 16452 14281 110157 13712 15461 16476 26401 26400 26395 26417 13869 LYSOPHOSPHATIDIC ACID LPA6 SIGNALLING%PATHWHIZ%PW064749 Lysophosphatidic Acid LPA6 Signalling 14688 67168 11651 19877 432530 20807 14702 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0000064 Fructose and Mannose Degradation 234730 75454 22122 21991 75540 331026 15275 230163 11674 14121 18641 20322 11677 16548 218138 29858 18639 110119 GLYCOGENOSIS, TYPE VI. HERS DISEASE%SMPDB%SMP0120619 Glycogenosis, Type VI. Hers Disease 110006 22239 15275 14751 PRACTOLOL ACTION PATHWAY%PATHWHIZ%PW000646 Practolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 GLYCOGENOSIS, TYPE VII. TARUI DISEASE%SMPDB%SMP0120815 Glycogenosis, Type VII. Tarui Disease 18642 15277 21991 14377 100043349 13806 18770 56012 319625 11674 14751 PAMIDRONATE ACTION PATHWAY%PATHWHIZ%PW000273 Pamidronate Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 PROLIDASE DEFICIENCY (PD)%PATHWHIZ%PW000083 Prolidase Deficiency (PD) 18125 14718 18242 18408 19125 18416 67092 12709 14431 69051 11846 11898 320452 109900 13142 107508 109093 212647 14661 227231 BILE ACID BIOSYNTHESIS%SMPDB%SMP0000035 Bile Acid Biosynthesis 16889 208665 83702 93732 12642 20280 13123 104086 13124 13122 15488 17117 12012 26459 13116 101502 56050 ZOLEDRONATE ACTION PATHWAY%PATHWHIZ%PW000270 Zoledronate Action Pathway 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 GLUTATHIONE SYNTHETASE DEFICIENCY%PATHWHIZ%PW000073 Glutathione Synthetase Deficiency 71522 14775 12369 68252 14630 14629 14854 14782 68214 75475 16790 CLOMIPRAMINE METABOLISM PATHWAY%PATHWHIZ%PW000615 Clomipramine Metabolism Pathway 107141 13077 13114 56448 CLARITHROMYCIN ACTION PATHWAY%SMPDB%SMP0000248 Clarithromycin Action Pathway SULINDAC ACTION PATHWAY%PATHWHIZ%PW000136 Sulindac Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 LEVOMETHADYL ACETATE METABOLISM PATHWAY%PATHWHIZ%PW000614 Levomethadyl Acetate Metabolism Pathway 13113 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0063614 Fructose and Mannose Degradation 18642 14120 21991 15275 230163 11676 PROTEIN SYNTHESIS: HISTIDINE%PATHWHIZ%PW112929 Protein Synthesis: Histidine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 15115 27050 27370 GLYCEROL METABOLISM IV (GLYCEROPHOSPHOGLYCEROL)%PATHWHIZ%PW000917 Glycerol Metabolism IV (Glycerophosphoglycerol) RIBOSE-5-PHOSPHATE ISOMERASE DEFICIENCY%SMPDB%SMP0000519 Ribose-5-phosphate Isomerase Deficiency 21881 11674 66171 14751 14121 75456 14381 18641 19895 72157 71336 21351 66646 110208 232449 DESIPRAMINE METABOLISM PATHWAY%PATHWHIZ%PW000602 Desipramine Metabolism Pathway 20538 56448 15567 HYDROFLUMETHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000335 Hydroflumethiazide Action Pathway 11931 11932 11933 11928 98660 69354 50934 56365 27411 110784 18399 20510 102680 20518 20278 20540 330836 17254 107723 20539 20276 20495 20497 20277 30962 20532 232975 INTRACELLULAR SIGNALLING THROUGH LHCGR RECEPTOR AND LUTEINIZING HORMONE CHORIOGONADOTROPIN%SMPDB%SMP0000338 Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone Choriogonadotropin 14688 12640 210044 18749 19045 16867 12912 14699 16866 LACTOSE DEGRADATION%SMPDB%SMP0000457 Lactose Degradation 20537 11931 11932 11933 11928 226413 98660 20526 232975 FRUCTOSE-1,6-DIPHOSPHATASE DEFICIENCY%SMPDB%SMP0000562 Fructose-1,6-diphosphatase Deficiency 55951 18563 17448 12183 21991 14377 75735 100043349 14385 13806 319625 20526 56012 11674 67863 14751 14121 18648 72157 15277 18534 16828 GLYCEROLIPID METABOLISM%SMPDB%SMP0000039 Glycerolipid Metabolism 15450 50784 14571 11670 11677 19012 235582 14732 55979 14555 16956 ETHANOL FERMENTATION%SMPDB%SMP0002356 Ethanol Fermentation 18746 21991 100043349 56421 14751 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW088358 Pentose Phosphate Pathway 14381 18641 19895 71336 21351 21881 11674 19139 14121 14751 SUCRASE-ISOMALTASE DEFICIENCY%PATHWHIZ%PW000533 Sucrase-Isomaltase Deficiency 216558 74185 14751 69983 232714 232493 110006 70974 72157 77559 100043686 15277 22235 103988 110095 TIGECYCLINE ACTION PATHWAY%PATHWHIZ%PW000689 Tigecycline Action Pathway DE NOVO TRIACYLGLYCEROL BIOSYNTHESIS%SMPDB%SMP0015896 De Novo Triacylglycerol Biosynthesis 14245 13350 14732 55979 14555 SPECTINOMYCIN ACTION PATHWAY%PATHWHIZ%PW000356 Spectinomycin Action Pathway HOMOCYSTINURIA, CYSTATHIONINE BETA-SYNTHASE DEFICIENCY%PATHWHIZ%PW000491 Homocystinuria, Cystathionine beta-Synthase Deficiency 107869 12411 HISTAPYRRODINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058732 Histapyrrodine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 PANTOPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000591 Pantoprazole Metabolism Pathway 11944 11945 VALSARTAN ACTION PATHWAY%SMPDB%SMP0000165 Valsartan Action Pathway 14688 11607 100038824 11606 11421 14702 14682 CARNOSINURIA, CARNOSINEMIA%SMPDB%SMP0000493 Carnosinuria, Carnosinemia 14415 268860 104776 11669 64705 99586 11754 103149 338403 GLYCOGENOSIS, TYPE IV. AMYLOPECTINOSIS, ANDERSON DISEASE%SMPDB%SMP0120837 Glycogenosis, Type IV. Amylopectinosis, Anderson Disease 110006 70974 71773 100043686 77559 216558 15277 22235 103988 110095 14751 2-AMINO-3-CARBOXYMUCONATE SEMIALDEHYDE DEGRADATION%SMPDB%SMP0121131 2-Amino-3-Carboxymuconate Semialdehyde Degradation 237320 209692 13382 266645 78920 BEVANTOLOL ACTION PATHWAY%PATHWHIZ%PW000645 Bevantolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 PROTEIN SYNTHESIS: TRYPTOPHAN%PATHWHIZ%PW120526 Protein Synthesis: Tryptophan 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 22375 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 65019 27050 27370 PURINE METABOLISM%PATHWHIZ%PW000052 Purine Metabolism 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 INOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0000462 Inositol Phosphate Metabolism 228550 327655 16329 71780 55980 234515 217837 75678 269180 17330 56409 27399 69718 ENOXAPARIN ACTION PATHWAY%SMPDB%SMP0000272 Enoxaparin Action Pathway 12842 110135 99571 18791 18815 14161 14068 11905 14060 14067 14066 74145 58992 109821 14058 16621 56316 14061 14071 27973 14069 SACCHAROPINURIA HYPERLYSINEMIA II%SMPDB%SMP0000239 Saccharopinuria Hyperlysinemia II 15107 209692 13382 270076 78920 110446 11988 23923 83885 93747 110695 19193 30956 ALIMEMAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059689 Alimemazine H1-Antihistamine Action 14688 18795 18751 18033 16438 15465 14702 14682 MALONIC ACIDURIA%SMPDB%SMP0000198 Malonic Aciduria 13382 110446 12039 68738 268860 12040 93747 227095 66904 110821 11364 13171 104776 56690 106557 107476 73724 AROMATASE DEFICIENCY%SMPDB%SMP0000565 Aromatase Deficiency 13075 54200 100559 13074 20860 78925 208665 15497 15487 15485 GLYCOGENOSIS, TYPE IC%PATHWHIZ%PW121894 Glycogenosis, Type IC 71803 269614 74551 69719 55951 17448 68401 12183 21991 15275 230163 13806 319625 14751 14447 239606 18648 14120 KIDNEY FUNCTION - DISTAL CONVOLUTED TUBULE%SMPDB%SMP0121012 Kidney Function - Distal Convoluted Tubule 11931 11932 20497 11933 11928 194352 98660 11827 56365 100038824 11828 20541 11944 11945 232975 ARGININOSUCCINIC ACIDURIA%PATHWHIZ%PW000184 Argininosuccinic Aciduria 76282 55963 20514 14719 78830 18408 18416 216456 11846 11898 109900 14661 227231 FOSINOPRIL METABOLISM PATHWAY%SMPDB%SMP0000594 Fosinopril Metabolism Pathway 11421 PINDOLOL ACTION PATHWAY%PATHWHIZ%PW000374 Pindolol Action Pathway 20648 11931 11932 243764 11933 11938 58226 11928 18747 16521 98660 16535 12291 16493 330953 16523 20927 16514 20271 22004 16519 16520 11554 16518 12288 20541 20650 56543 16525 16509 56808 12295 13383 16511 20191 20928 246133 232975 19084 20649 FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS%SMPDB%SMP0108224 Fc Epsilon Receptor I Signaling in Mast Cells 18750 16331 18803 14125 16163 16189 20963 16653 19353 17060 16818 14784 18176 17096 16797 12981 26419 14126 110157 15461 11651 18708 26400 14360 26395 26396 26413 21926 14389 SUCCINATE SIGNALLING DURING INFLAMMATION%SMPDB%SMP0084634 Succinate Signalling During Inflammation 18750 18795 12912 84112 26413 19094 18127 12675 19224 18033 16151 16150 26417 TAMOXIFEN ACTION PATHWAY%SMPDB%SMP0000471 Tamoxifen Action Pathway 20887 13982 14262 13114 14261 394433 13088 56448 394434 MITOCHONDRIAL DNA DEPLETION SYNDROME-3%SMPDB%SMP0000536 Mitochondrial DNA Depletion Syndrome-3 15452 75456 11564 16434 11486 23984 67054 67979 11636 229363 210044 14450 54369 76952 238871 53893 231327 229665 108147 11821 22436 23917 14923 66355 11566 54195 66401 12499 14544 27369 20135 20133 237823 18950 72090 22166 234889 D4-GDI SIGNALING PATHWAY%SMPDB%SMP0066935 D4-GDI Signaling Pathway 670717 18646 330914 11545 11855 11857 12370 12362 12367 11783 12371 16476 14939 FRUCTOSURIA%PATHWHIZ%PW121881 Fructosuria 18642 14120 21991 15275 230163 11676 ARACHIDONIC ACID METABOLISM%SMPDB%SMP0000075 Arachidonic Acid Metabolism 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 5-OXOPROLINURIA%PATHWHIZ%PW000074 5-Oxoprolinuria 71522 14775 12369 68252 14630 14629 14854 14782 68214 75475 16790 ETORICOXIB ACTION PATHWAY%SMPDB%SMP0000695 Etoricoxib Action Pathway 71519 14775 208285 17001 19223 13850 100040843 13088 13110 16993 11684 106648 105349 64292 19215 11689 11686 21391 11687 11688 19224 19225 12408 72303 14598 13106 72054 66469 PROTEIN SYNTHESIS: ASPARAGINE%SMPDB%SMP0111854 Protein Synthesis: Asparagine 20115 319195 67248 100043391 668182 241053 100040331 432502 670832 633683 100043184 667279 668144 100043755 100043209 382492 621100 665189 666899 67281 100042670 629957 100039316 667739 76846 225058 19921 100038875 100038991 100043876 267019 100043000 100043423 100042986 16785 20044 100043295 100040298 625646 622534 100042740 667618 56040 57294 666669 100040021 100040970 20085 20084 19899 67891 67097 19934 66481 67025 19941 14694 20055 27207 68193 67186 19989 19951 76808 75617 20103 20102 22121 70223 65019 27050 27370 FANCONI-BICKEL SYNDROME%PATHWHIZ%PW121892 Fanconi-Bickel Syndrome 18663 68401 12183 21991 15275 230163 13806 319625 56421 14751 14447 18746 239606 18648 INTRACELLULAR SIGNALLING THROUGH HISTAMINE H2 RECEPTOR AND HISTAMINE%PATHWHIZ%PW000449 Intracellular Signalling Through Histamine H2 Receptor and Histamine 14688 210044 18749 19045 12912 14699 15466 DESMOSTEROLOSIS%PATHWHIZ%PW000097 Desmosterolosis 73166 20652 66234 16889 235293 68603 18194 14593 110460 16987 192156 15357 110196 319554 14137 13121 15490 17855 13595 20775 74754 LYSOPHOSPHATIDIC ACID LPA3 SIGNALLING%SMPDB%SMP0063755 Lysophosphatidic Acid LPA3 Signalling 14688 18795 11651 432530 16438 14702 65086 THE ONCOGENIC ACTION OF 2-HYDROXYGLUTARATE%SMPDB%SMP0002291 The Oncogenic Action of 2-Hydroxyglutarate 269951 66945 55951 18563 67834 56451 66925 209692 20917 11429 216456 13382 14194 235339 68263 15926 170718 11428 18597 15929 78920 67680 66052 12974 GLYCEROL METABOLISM V (GLYCEROPHOSPHOSERINE)%SMPDB%SMP0121313 Glycerol Metabolism V (Glycerophosphoserine)