MIR219 IN OLIGODENDROCYTE DIFFERENTIATION AND MYELINATION%WIKIPATHWAYS_20260910%WP2811%RATTUS NORVEGICUS mir219 in oligodendrocyte differentiation and myelination Zbtb18 Foxj3 Pdgfra Elovl7 Neurod1 Sox6 Hes5 P38 MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP294%RATTUS NORVEGICUS p38 Mapk signaling pathway Atf2 Shc1 Max Pla2g4a Map3k9 Elk1 Mef2d Map3k7 Map2k6 Map3k5 Tgfb2 Tradd Hspb1 Traf2 Rac1 Cdc42 Mapk14 Mapkapk2 Ripk1 Mapkapk5 Map2k4 Map3k1 Rps6ka5 Mknk1 Grb2 Tgfbr1 Daxx Hras APOPTOSIS%WIKIPATHWAYS_20260910%WP1290%RATTUS NORVEGICUS Apoptosis Tnfrsf1a Akt1 Nfkb1 Traf1 Tp53 Bcl2l2 Xiap Rela Bnip3l Irf3 Irf4 Irf1 Irf2 Pmaip1 Tnfrsf10b Lta Irf7 Irf5 Fadd Irf6 Pik3r1 Diablol1 Bak1 Bid Tp73 Nfkbib Casp7 Jun Casp9 Bad Casp3 Tnfrsf25 Igf2 Casp2 Nfkbia Bax Fas Chuk Faslg Igf1r Dffa Dffb Tp63 Mapk10 Tradd Traf2 Ripk1 Map2k4 Map3k1 Ikbkb Ikbkg Prf1 Birc5 Tnfrsf1b Hells Bcl2l11 GLUCOCORTICOID EFFECT ON TARGET GENE EXPRESSION%WIKIPATHWAYS_20260910%WP1963%RATTUS NORVEGICUS Glucocorticoid effect on target gene expression Pla2g4a Anxa1 Mt-co2 Nfkb1 Fkbp4 Nfkbia Tsc22d3 Nr3c1 Hspa4 Rras ESTROGEN METABOLISM%WIKIPATHWAYS_20260910%WP1302%RATTUS NORVEGICUS Estrogen metabolism Sult1e1 Nqo1 Gstm1 Comt Sult1a1 Arsl Cyp1a1 Cyp1b1 NUCLEAR RECEPTORS%WIKIPATHWAYS_20260910%WP217%RATTUS NORVEGICUS Nuclear receptors Esrra Esrrb Rara Rarb Nr2f6 Thrb Nr1d2 Thra Nr2f2 Vdr Nr2f1 Nr1h3 Rorc Nr1h2 Ppard Ppara Esr1 Pparg Esr2 Rxrb Rxra Ror1 Rxrg Nr5a2 Nr5a1 Nr4a2 Nr3c1 Nr2c2 Nr2e1 Hnf4a Nr1i3 Nr1i2 LIPID DROPLET METABOLISM%WIKIPATHWAYS_20260910%WP3901%RATTUS NORVEGICUS Lipid droplet metabolism Plin2 Pnpla2 Bscl2 Dgat2 Agpat5 Acsl1 Dgat1 Gpd2 Acsl3 Agpat3 Fitm2 Agpat4 Agpat1 Agpat2 Soat1 Lpin3 Aup1 Lipa Gpat2 Lpin1 INSULIN SIGNALING%WIKIPATHWAYS_20260910%WP439%RATTUS NORVEGICUS Insulin signaling Akt1 Pik3r1 Jun Igf1r Mapk10 Mapk9 Cyth3 Mapk8 Grb14 Mapk1 Trib3 Irs2 Map3k8 Grb10 Map3k6 Mapk3 Mapk4 Map3k4 Stxbp1 Stxbp2 Stxbp3 Stxbp4 Prkaa1 Prkaa2 Akt2 Reg1 Gyg1 Kif5b Cblc Tsc2 Cblb Tsc1 Prkcq Map3k3 Map3k2 Prkch Prkci Prkcb Prkcd Prkca Raf1 Shc3 Shc2 Insr Eif4ebp1 Flot2 Flot1 Map4k5 Map4k3 Rab4a Rps6kb1 Rheb Rps6kb2 Pik3cg Prkcz Pik3cd Egr1 Xbp1 Kif3a Tbc1d4 Pik3c2a Pik3c2g Map4k2 Ehd1 Map4k1 Ehd2 Snap25 Snap23 Lipe Rptor Arf1 Pik3c3 Gys1 Gys2 Pdpk1 Rhoj Rac2 Slc2a1 Slc2a4 Ptprf Foxo3 Foxo1 Cap1 Rrad Inpp4a Gab1 Fos Ppp1r3a Vamp2 Eif4e Gsk3b Rps6ka3 Rps6ka4 Gsk3a Rps6ka6 Rps6ka1 Mink1 Rps6ka2 Sgk3 Sos2 Sgk2 Crk Sos1 Pik3r2 Sgk1 Myo1c Enpp1 Map2k7 Mtor Pfkl Ptpn1 Ptpn11 Stx4 Arhgap33 Inppl1 Mapk12 Mapk13 Shc1 Pten Sh2b2 Map2k2 Map3k9 Map2k1 Elk1 Rapgef1 Map3k10 Map3k7 Map3k11 Map2k6 Map3k14 Map3k5 Mapk11 Rac1 Mapk14 Map2k4 Map3k1 Rps6ka5 Grb2 Hras Ikbkb S1P RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260910%WP1312%RATTUS NORVEGICUS S1P receptor signal transduction Akt2 Akt1 Smpd2 Plcb3 Pik3c2b Plcb2 Plcb1 Asah1 Sphk2 Akt3 Sphk1 S1pr1 Gnai1 Mapk1 S1pr3 Gnai3 Mapk3 Mapk4 Mapk12 AFLATOXIN B1 METABOLISM%WIKIPATHWAYS_20260910%WP1300%RATTUS NORVEGICUS Aflatoxin B1 metabolism Akr7a3 Gstm1 Akr7a2 Ephx1 HEPATOCYTE GROWTH FACTOR RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP94%RATTUS NORVEGICUS Hepatocyte growth factor receptor signaling Pik3ca Hgf Ptk2b Ptk2 Itgb1 Stat3 Met Crk Sos1 Raf1 Ptpn11 Jun Pten Map2k2 Map2k1 Elk1 Rapgef1 Map4k1 Mapk8 Mapk1 Grb2 Src Rasa1 Mapk3 Hras Pxn Dock1 Crkl Pak1 Itga1 Rap1a Gab1 Rap1b Fos NOD LIKE RECEPTOR NLR SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP1294%RATTUS NORVEGICUS Nod like receptor NLR signaling pathway Mapk8 Map3k7 Chuk Cd40 Rela Ephb2 Ikbkb Ikbkg APOPTOSIS MODULATION BY HSP70%WIKIPATHWAYS_20260910%WP487%RATTUS NORVEGICUS Apoptosis modulation by HSP70 Tnfrsf1a Casp2 Nfkb1 Fas Faslg Cycs Casp6 Aifm1 Mapk10 Hspa1b Ripk1 Map3k1 Fadd Bid Casp7 Casp9 Casp3 BETA OXIDATION OF UNSATURATED FATTY ACIDS%WIKIPATHWAYS_20260910%WP418%RATTUS NORVEGICUS Beta oxidation of unsaturated fatty acids Acadm Decr1 Hadha Hadhb Eci1 ADIPOGENESIS%WIKIPATHWAYS_20260910%WP155%RATTUS NORVEGICUS Adipogenesis Stat3 Socs3 Ins2 Nampt Nrip1 Ahr Tnf Lifr Prlr Cyp26b1 Foxc2 Wnt5b Twist1 Ebf1 Mif Retn Cyp26a1 Mbnl1 Frzb Cntfr Fas Gata3 Serpine1 Gata4 Gata2 Cfd Lpl Gh1 Il6 Nr3c1 Tgfb1 Hif1a Dvl1 Id3 Gtf3a Ndn Cisd1 Pck1 Pck2 Egr2 Lif Igf1 Bmp4 Bmp3 Wwtr1 Stat5a Bmp2 Stat5b Bmp1 Hnf1a Hmga1 Adipoq Rara Necab3 Epas1 Scd1 Sfrp4 Ptgis Rbl2 Rbl1 Nr2f1 Klf15 Nr1h3 Ncor1 Il6st Ucp1 Ppard Gadd45b Ppara Gadd45a Pnpla3 Pparg Cebpd Cebpb Ncoa2 Rxra Zmpste24 Ncoa1 Rxrg Rb1 Asip Osm Ppargc1a Celf1 Lpin3 Dlk1 Mixl1 Agt Mef2a Lpin1 Mef2b Plin2 Mef2c Klf5 Bscl2 Lep Spock1 E2f1 Cdkn1a Gdf10 Srebf1 Agpat2 Trib3 Irs2 Lipe Slc2a4 Foxo1 Mef2d SMALL LIGAND GPCRS%WIKIPATHWAYS_20260910%WP161%RATTUS NORVEGICUS Small ligand GPCRs Mtnr1a Cnr1 Cnr2 Ptgdr Ptgir Ptger4 Ptgfr Ptger2 Ptafr S1pr1 Ptger3 Ptger1 S1pr3 Lpar1 BIOSYNTHESIS OF ALDOSTERONE AND CORTISOL%WIKIPATHWAYS_20260910%WP508%RATTUS NORVEGICUS Biosynthesis of aldosterone and cortisol Hsd3b6 Cyp21a1 Cyp17a1 HYPOTHETICAL NETWORK FOR DRUG ADDICTION%WIKIPATHWAYS_20260910%WP1281%RATTUS NORVEGICUS Hypothetical network for drug addiction Gria2 Camk2b Map2k1 Gria1 Ppa1 Prkce Drd1 Grin1 Grin2d Adcy8 Grin2c Drd4 Grin2b Mapk1 Acta1 Grin2a Mapk3 Nisch Camk4 Krit1 Prkaca Terf2ip Grm1 Grm5 SPINAL CORD INJURY%WIKIPATHWAYS_20260910%WP2433%RATTUS NORVEGICUS Spinal cord injury Tp53 Grin1 Btg2 Chst11 Bdnf Fkbp1a Ptprz1 Prkca Slit1 Slit2 Aqp4 Slit3 Pdyn Rgma Vcan Gja1 Ifng Sema6a Lilrb2 Nos1 Sox9 Tnfsf13b Casp3 Zfp36 Gap43 Arg1 Egr1 Prpg2 Omg Mmp9 Plxna2 Epha4 Mag Rtn4r Tacr1 Tlr4 Ngfr Cxcl10 Il6 Pla2g2a Tgfb1 Ccng1 Ntn1 Anxa1 Klk8 Il2 Rtn4 Gfap Il4 Selp Bcan Tnfsf13 C5 Gdnf Ccl2 Pla2g5 Mbp Cd47 Cxcl1 Fos Cxcl2 Pla2g6 Ppp3ca Fcgr2a Necab3 Ccnd1 Nos2 Ptpra Ncan Col4a1 Acan Il1a Il1b Xylt1 Nox4 Cdk1 Rock2 Gadd45a Il1r1 Vim E2f5 Rb1 E2f1 Mapk1 Mapk3 HEXOSES METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260910%WP3916%RATTUS NORVEGICUS Hexoses metabolism in proximal tubules Pdp1 Pdp2 Pck1 Gpi Pdhx Psme3 Slc5a10 Sord Pfkl Eno1 Eno3 Eno2 Khk Pc Mpc1 Mpc2 Pdk4 Pgam2 Slc2a2 Pdk3 Pgam1 Akr1b1 Slc2a5 Pdk2 Pdk1 Tpi1 Pdhb Gapdh Tkfc Ldha Ldhb Fbp1 Dld Pklr Aldob Aldoc Aldoa Acly Pdha1 Pgk1 Slc5a1 Slc5a2 Pfkp Slc5a9 Got1 Mdh1 Mdh2 Got2 G6pc1 Hk1 METHYLATION%WIKIPATHWAYS_20260910%WP1282%RATTUS NORVEGICUS Methylation Pnmt Mat2a Mat1a Inmt Comt Hnmt MATRIX METALLOPROTEINASES%WIKIPATHWAYS_20260910%WP278%RATTUS NORVEGICUS Matrix metalloproteinases Mmp9 Mmp11 Cep295nl Mmp23 Mmp24 Mmp14 Mmp15 Mmp16 Mmp2 Mmp28 Timp3 Timp2 Timp4 Bsg Tcf20 Mmp21 Tnf GPCRS OTHER%WIKIPATHWAYS_20260910%WP409%RATTUS NORVEGICUS GPCRs other Drd4 Prokr2 Adora2a Adgrg1 Cxcr1 Ednra Gnrhr Ntsr1 Htr7 Fshr Grm8 Htr2a Gpr61 Or1n1 Ccr5 Ccr2 Gpr176 Adra1d Cckbr Alg6 Adgrl2 Adgrl3 Gpr135 Sstr2 Smo Htr1f Taar3 Rxfp3 Taar2 Rxfp1 Taar5 Ghrhr Gpr183 C5ar2 F2r Or3a1e Or2a5 Chrm3 Chrm2 Hrh4 Gpr88 Or2f1 Drd3 Celsr2 Gpr18 Grpr Uts2r P2ry13 Gpr17 Ltb4r2 Lgr6 Or10a2 Cnr1 Ptgfr S1pr1 Grm1 GENETIC ALTERATIONS OF LUNG CANCER%WIKIPATHWAYS_20260910%WP1968%RATTUS NORVEGICUS Genetic alterations of lung cancer Pik3ca Pik3cd Map2k1 Akt1 Ccnd1 Necab3 E2f1 Tp53 Cdkn1a Tgfb2 Ccne1 Erbb2 Dmp1 Egfr Mycb Tgfb1 Crebbp Rasl11b Smad2 Smad4 Raf1 Mapk1 Mdm2 Rb1 BURN WOUND HEALING%WIKIPATHWAYS_20260910%WP5057%RATTUS NORVEGICUS Burn wound healing Tp53 Col4a1 Ptgis Il1b Il10 Adora2b Epo Dll4 Pdgfa Arfgap1 Ccn2 Col1a1 Jun Syk Chp1 Ankrd1 Casp3 Syp Il1rl1 Glb1 Cdc25b Mmp9 Gpr176 Acta1 Igf1 TRANSCRIPTIONAL ACTIVATION BY NFE2L2 IN RESPONSE TO PHYTOCHEMICALS%WIKIPATHWAYS_20260910%WP1280%RATTUS NORVEGICUS Transcriptional activation by Nfe2l2 in response to phytochemicals Mapk8 Prkca Aimp2 Cebpb Maf Nqo1 Hmox1 Gclm Nfe2l2 Ephb2 TYPE II INTERFERON SIGNALING IFNG %WIKIPATHWAYS_20260910%WP1289%RATTUS NORVEGICUS Type II interferon signaling IFNG Reg1 Nos2 Irf4 Il1b Irf1 Irf2 Prkcd Socs3 Ptpn11 Ifng Spi1 Eif2ak2 Cxcl9 Ifnb1 Ifngr2 Cxcl10 Oas1a Ifngr1 Psmb9 Jak2 Gbp1 Jak1 Hist1h4m Tap1 Ciita Cybb Irf8 Isg15 Irf9 Ifit2 RETINOL METABOLISM%WIKIPATHWAYS_20260910%WP1297%RATTUS NORVEGICUS Retinol metabolism Rdh10 Adh5 Adh4 Rara Adh1 Rarb Bco1 Npc1l1 Rpe65 Rbp7 Abcg8 Abcg5 Rbp4 Scarb1 Cyp2e1 Retsat Crabp2 Cd36 Lrat Rlbp1 Rxrb Rxra Rxrg Cyp26b1 Cyp26a1 Lpl Sult1a1 Dhrs3 Aldh1a1 Sult2b1 Cd36l1 Rdh12 Aldh1a3 FOLIC ACID NETWORK%WIKIPATHWAYS_20260910%WP1311%RATTUS NORVEGICUS Folic acid network Cat Pnpo Xdh Mthfr Selenok Ptgis Mt-co2 Fads2 Mt-co1 Gpx1 Gpx3 Gpx6 Alox5 Msrb1 Mtr Selenow Kmo Sod1 Ptgds Txnrd2 Cbs NUCLEAR RECEPTORS IN LIPID METABOLISM AND TOXICITY%WIKIPATHWAYS_20260910%WP139%RATTUS NORVEGICUS Nuclear receptors in lipid metabolism and toxicity Rara Rarb Vdr Abcg5 Nr1h3 Cyp2e1 Ppard Ppara Pparg Cyp26a1 Abcb1a Abcd2 Cyp27b1 Abcd3 Cyp2c11 Abcb4 Cyp4b1 Cyp2b2 Cyp8b1 Abcg1 Abca1 Abcc3 Cyp24a1 Abcc2 Cyp7a1 Abcb11 Nr1i3 Nr1i2 KIT RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP147%RATTUS NORVEGICUS Kit receptor signaling pathway Akt1 Stat3 Cblb Prkcb Tnfrsf10b Prkca Raf1 Pik3r1 Bad Pik3cg Stap1 Mitf Socs5 Socs4 Matk Socs6 Ptpru Csf2rb Stat5a Cltc Sh3kbp1 Stat5b Plcg1 Vav2 Fgr Dok1 Hck Kit Btk Spred1 Mpdz Rps6ka1 Spred2 Grb7 Ptpn6 Abl1 Fyn Grap Crk Lyn Sos1 Plce1 Pik3r2 Tec Fes Ptpn11 Shc1 Sh2b2 Map2k1 Jak2 Mapk1 Grb2 Grb10 Src Rasa1 Hras Crkl INTRACELLULAR TRAFFICKING OF CFTR%WIKIPATHWAYS_20260910%WP1486%RATTUS NORVEGICUS Intracellular trafficking of CFTR Cftr Nherf1 Fblim1 Ezr Rab7a Rab11a CARDIOVASCULAR SIGNALING%WIKIPATHWAYS_20260910%WP590%RATTUS NORVEGICUS Cardiovascular signaling Vav2 Akt1 Col4a1 Erbb2 Casp6 Hspa1b Arhgef7 Pdgfra Col11a1 Stmn1 Col1a1 Tnc Rras2 Wnt2 Vegfd Casp3 Wasf1 Selenop Vwf Casp2 Egf Capn6 Col5a1 Map2k6 Col4a2 Cfl1 Pgf Thbs2 Hspb1 Mapk8 PROTEASOME DEGRADATION%WIKIPATHWAYS_20260910%WP302%RATTUS NORVEGICUS Proteasome degradation Psmb1 Psmd3 Psmd2 Psmd5 Psmd4 Psmb2 Ube2d3 Ube2d1 Psmc6 Psmc5 Psma5 Psmc2 Rpn2 Psma2 Psmb9 Psmc4 Psmc3 Rpn1 Psme2 Psme1 Psmd12 Psmd11 Ube2b Psmd13 Uchl3 Psmb8 Psmb6l1 Psmb5 Psmd6 Psmb7 Psmd8 Uchl1 TCA CYCLE%WIKIPATHWAYS_20260910%WP347%RATTUS NORVEGICUS TCA cycle Pdk3 Pdk2 Fh Pdhb Sdhc Sdhb Sdha Idh3b Afdn Suclg1 Dld Suclg2 Ogdh Pdha1 Mdh1 Pc Mdh2 Pdk4 VEGF RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260910%WP1965%RATTUS NORVEGICUS VEGF receptor signal transduction Akt1 Pgf Rac1 Prkci Mapkapk2 Prkca Sh2d2a Raf1 Nos3 Mapk1 Hspbp1 Vegfc Grb2 Pik3r3 Vegfb Src Pxn Casp9 Bad Shc1 Plcg1 NUCLEOTIDE METABOLISM%WIKIPATHWAYS_20260910%WP146%RATTUS NORVEGICUS Nucleotide metabolism Adss2 Sat1 Srm Dhfr Pold1 Prps2 Polb Impdh1 Nme2 Mthfd2 Hprt1 Polg IRINOTECAN PATHWAY%WIKIPATHWAYS_20260910%WP124%RATTUS NORVEGICUS Irinotecan pathway Abcc2 Bche Abcc1 Ces1f Ces1e Ces1d Ces2c Abcg2 NOTCH SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP517%RATTUS NORVEGICUS Notch signaling pathway Notch2 Lfng Notch3 Psen1 Psen2 Crebbp Dll4 Hes5 Aph1a Ncstn Dtx2 Dtx3 Dtx4 Dll3 Dvl1 Rbpjl Maml1 Ctbp1 Ctbp2 Hdac1 Mfng Dvl2 Hes1 Numb Dvl3 Jag2 Jag1 Kat2a Rfng Numbl Notch1 ONE CARBON METABOLISM%WIKIPATHWAYS_20260910%WP1292%RATTUS NORVEGICUS One carbon metabolism Mthfr Mat1a Mthfd1l Ahcy Folh1 Mtrr Ftcd Ahcyl2 Bhmt Tcn2 Dnmt3a Aldh1l1 Shmt1 Gart Dhfr Mtr Mthfd2 ETHANOL METABOLISM RESULTING IN PRODUCTION OF ROS BY CYP2E1%WIKIPATHWAYS_20260910%WP4268%RATTUS NORVEGICUS Ethanol metabolism resulting in production of ROS by CYP2E1 Mapk8 Mafg Map2k1 Nfe2l2 Cyp2e1 Prkcb GLUCURONIDATION%WIKIPATHWAYS_20260910%WP1276%RATTUS NORVEGICUS Glucuronidation Ugt2b1 Ugt2b7 Pgm2 Pgm5 Ugt2b35 Ugt2b34 Ugt2a1 Ugp2 Ugdh Pgm1 Hk1 ERBB SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP1299%RATTUS NORVEGICUS ErbB signaling pathway Ptk2 Gsk3b Cblc Erbb2 Abl1 Egfr Crk Sos1 Prkca Shc2 Map2k7 Eif4ebp1 Mtor Rps6kb1 Jun Ereg Hbegf Bad Camk2a Pak4 Tgfa Nrg2 Map2k1 Elk1 Egf Nrg1 Areg Btc Nrg4 Cdkn1a Nrg3 Pik3r5 Cdkn1b Akt3 Mapk8 Mapk1 Grb2 Src Hras Stat5a Gab1 Plcg1 STATIN PATHWAY%WIKIPATHWAYS_20260910%WP145%RATTUS NORVEGICUS Statin pathway Cyp7a1 Apoc1 Mttp Soat1 Lpl Scarb1 Hmgcr Apoe Lcat Abca1 OXIDATIVE STRESS RESPONSE%WIKIPATHWAYS_20260910%WP173%RATTUS NORVEGICUS Oxidative stress response Cat Nfkb1 Xdh Hmox1 Mapk10 Mapk14 Nfix Sod3 Sod2 Txn2 Cyba Gstt2 Nqo1 Mgst1 Gpx3 Junb Cyp1a1 Sod1 Txnrd2 Fos NON HOMOLOGOUS END JOINING%WIKIPATHWAYS_20260910%WP1277%RATTUS NORVEGICUS Non homologous end joining Xrcc6 Rad50 Prkdc Xrcc4 FATTY ACID OMEGA OXIDATION%WIKIPATHWAYS_20260910%WP133%RATTUS NORVEGICUS Fatty acid omega oxidation Adh5 Adh4 Adh1 Cyp1a1 Aldh2 Aldh1a1 Cyp4a2 Cyp2e1 Cyp3a2 Adh7 Adh6 Acad10 SELENIUM MICRONUTRIENT NETWORK %WIKIPATHWAYS_20260910%WP1310%RATTUS NORVEGICUS Selenium micronutrient network Tbxas1 Selenop Cat Fads1 Pnpo Xdh Mthfr Selenok Ptgis Mt-co2 Fads2 Mt-co1 Gpx1 Gpx3 Gpx6 Alox5 Mtr Kmo Sod1 Ptgds HOMOLOGOUS RECOMBINATION%WIKIPATHWAYS_20260910%WP1296%RATTUS NORVEGICUS Homologous recombination Pold2 Rad51 Brca2 Rad52 Pold4 Rad50 Pold3 Pold1 Fsbp Nbn SEROTONIN AND ANXIETY%WIKIPATHWAYS_20260910%WP2132%RATTUS NORVEGICUS Serotonin and anxiety Htr2a Htr1a Ppp3ca Grin2d Nlgn1 Adra1a Arc Plek Prkcb Crh Htr2c Fos IL 3 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP319%RATTUS NORVEGICUS IL 3 signaling pathway Pik3ca Akt1 Nfkb1 Ptk2 Stat3 Mmp2 Prkcb Prkca Mapk7 Raf1 Socs3 Ywhaq Kcnip3 Ywhab Pik3r1 Fcer2 Ppp2ca Bcl2l1 Rack1 Gab2 Dnm1 Lck Vcl Chek1 Rps6kb2 Bad Il3ra Il3 Id1 Pik3cd Bmx Bax Mmp9 Gata2 Rac2 Selp Slc2a1 Matk Foxo1 Csf2rb Stat5a Gab1 Stat5b Rara Gsk3b Hck Gsk3a Ptpn6 Fyn Crk Lyn Sos1 Pik3r2 Tec Fes Rxra Ptpn11 Syk Atf2 Shc1 Map2k1 Rapgef1 Spi1 Hspb1 Rac1 Cdc42 Mapk14 Mapk9 Mapkapk2 Jak2 Mapk8 Jak1 Mapk1 Grb2 Src Mapk3 Hras Pxn Crkl Birc5 Prkaca Pak1 Tnfrsf1b Rap1a Bcl2l11 MONOAMINE GPCRS%WIKIPATHWAYS_20260910%WP276%RATTUS NORVEGICUS Monoamine GPCRs Drd1 Drd4 Adra1a Htr2c Htr1a Htr7 Htr2a Adra2a Adra2c Adra2b Htr4 Chrm1 Adra1d Hrh1 Htr6 Chrm5 Chrm4 Hrh2 Adrb1 Drd5 Adra1b Htr1f Adrb3 Htr1d Htr5b Htr5a Chrm3 Chrm2 Drd3 INSULIN INDUCED PI3K AKT AND MAPK IN HEPATOCYTES%WIKIPATHWAYS_20260910%WP4229%RATTUS NORVEGICUS Insulin induced PI3K Akt and MAPK in hepatocytes Akt1 Eif4e Tsc2 Gsk3a Tsc1 Rps6ka1 Sos1 Raf1 Eif4ebp1 Mtor Rps6kb1 Rheb Bad Shc1 Rptor Pik3c3 Gys1 Mapk1 Gys2 Ins1 Acly Irs2 Pfkfb2 Foxk1 Grb2 Grb10 Akt1s1 Rps6 Mapk3 Mlst8 Foxo1 SYNTHESIS AND DEGRADATION OF KETONE BODIES%WIKIPATHWAYS_20260910%WP349%RATTUS NORVEGICUS Synthesis and degradation of ketone bodies Hmgcl Bdh1 Oxct1 Hmgcs2 MITOCHONDRIAL GENE EXPRESSION%WIKIPATHWAYS_20260910%WP1301%RATTUS NORVEGICUS Mitochondrial gene expression Mterf1 Esrra Ppp3ca Nrf1 Ppargc1b Gabpa Myef2 Gabpb2 Tfam Pprc1 Ppargc1a Camk4 Tfb1m Tfb2m Prkar1b GLUCOCORTICOID METABOLISM%WIKIPATHWAYS_20260910%WP305%RATTUS NORVEGICUS Glucocorticoid metabolism Cyp21a1 Cyp17a1 Cyp11a1 Akr1c9 Hsd11b1 Hsd11b2 COMPLEMENT AND COAGULATION CASCADES%WIKIPATHWAYS_20260910%WP547%RATTUS NORVEGICUS Complement and coagulation cascades Serpine1 Cfd F2r Cr2 Serping1 Cr1l Kng2l1 C3ar1 Serpinf2 Mbl1 Fgb Masp1 Masp2 Tfpi F2 C8b F3 F7 F8 F9 Plaur Cfb C1qb C1qa Vwf Cd59b Cfh Cfi Plg Klkb1 Kng2 C2 Proc C4 C6 C9 Serpind1 F13b Cd46 F10 C1s C1r F12 Plat Thbd Plau Pros1 Serpinc1 A2m Cpb2 Cd55 C1qc RENIN ANGIOTENSIN SYSTEM%WIKIPATHWAYS_20260910%WP376%RATTUS NORVEGICUS Renin angiotensin system Agtr2 Pik3ca Ace2 Ren1 Ptk2b Enpep Ptk2 Ctsa Nln Stat3 Pak6 Rela Cma1 Lnpep Prkcq Pak3 Pak2 Pak5 Ace Anpep Mas1 Itpr3 Itpr2 Raf1 Itpr1 Jun Mapk10 Fos Map2k7 Atf2 Mapk13 Agt Shc1 Pak4 Elk1 Plcb1 Rac1 Ptgir Mapk9 Jak2 Mapk8 Map2k4 Mapk1 Map3k1 Grb2 Mapk3 Ikbkb Ikbkg Ctsg Prkaca Pak1 Cpa3 Mme Agtr1 MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP358%RATTUS NORVEGICUS MAPK signaling pathway Tnfrsf1a Akt1 Nfkb1 Tp53 Rela Pak2 Cacng8 Cacna1g Cacna1h Cacna1e Cacng7 Cacna1f Cacna1c Cacna1d Cacna1a Cacna1b Jun Cacng1 Fgf2 Cacng4 Casp3 Fgf1 Cacng5 Fgf4 Fgf3 Cacng3 Fgf6 Fas Fgf5 Chuk Elk4 Faslg Fgf8 Fgf7 Cacna1s Fgf9 Map3k20 Mapk10 Lamtor3 Prkcg Tgfb1 Nras Flna Rras Rasgrp3 Rasgrp4 Rasgrp1 Flnc Rasgrp2 Flnb Jund Nlk Stk4 Tgfb3 Pdgfrb Nf1 Tmem97 Ppp3cc Ppp3cb Fgfr3 Fgfr4 Fgfr1 Fgfr2 Rasgrf2 Tab2 Cd14 Fgf16 Fgf17 Fgf14 Ppp5c Pla2g4b Traf6 Egfr Fgf18 Pla2g4e Fgf19 Pla2g4d Gadd45a Braf Fgf12 Fgf13 Fgf10 Fgf11 Nfkb2 Nfatc1 Pdgfa Mapt Nfatc3 Fgf20 Prkacb Ngf Cacna2d1 Cacna2d3 Cacna2d4 Gna12 Dusp16 Mef2c Cdc25b Ppm1b Ptpn7 Ptpn5 Dusp3 Ntf4 Dusp2 Hspa1l Dusp4 Ntf3 Arrb2 Arrb1 Dusp10 Dusp9 Mapk9 Dusp8 Cacnb4 Mapk8 Cacnb1 Cacnb2 Mapk1 Taok2 Taok1 Taok3 Map3k8 Mos Ntrk2 Map3k6 Ntrk1 Mapk3 Rapgef2 Mapk8ip1 Map3k4 Mapk8ip3 Il1r2 Prkaca Akt2 Map3k2 Bdnf Prkcd Prkca Raf1 Map4k3 Map4k2 Map4k1 Fos Ppp3ca Rps6ka3 Rps6ka4 Il1a Il1b Sos2 Crk Sos1 Il1r1 Map2k7 Stmn1 Rras2 Atf2 Mapk13 Pla2g4a Map2k1 Elk1 Egf Map3k7 Map3k11 Map2k6 Map3k14 Map3k5 Tgfb2 Hspb1 Traf2 Rac1 Cdc42 Mapk14 Akt3 Mapkapk2 Mapkapk5 Map2k4 Map3k1 Mknk1 Grb2 Tgfbr1 Daxx Rasa1 Hras Ikbkb Ikbkg Crkl Pak1 Rap1a PHASE I BIOTRANSFORMATIONS NON P450%WIKIPATHWAYS_20260910%WP1291%RATTUS NORVEGICUS Phase I biotransformations non P450 Ces2j Esd Pon3 Ces5a Lipa Pon1 Pon2 ACE INHIBITOR PATHWAY%WIKIPATHWAYS_20260910%WP557%RATTUS NORVEGICUS ACE inhibitor pathway Agtr2 Ren1 Nos3 Agtr1b Bdkrb2 Kng2 Ace Agt Kng2l1 REGULATION OF ACTIN CYTOSKELETON%WIKIPATHWAYS_20260910%WP351%RATTUS NORVEGICUS Regulation of actin cytoskeleton Pik3ca Ptk2 Pak6 Pak3 Pak2 Pak5 Ins2 Pik3r1 Pik3r3 Fgf2 Fgf1 Fgf4 Fgf3 Fgf6 Fgf5 Fgf8 Fgf7 Fgf9 Nras Rras F2r Chrm3 Pdgfrb Chrm2 Fgfr3 Fgfr4 Fgfr1 Fgfr2 Cd14 Fgf16 Fgf17 Fgf14 Egfr Fgf18 Fgf19 Braf Fgf12 Fgf13 Fgf10 Fgf11 Pdgfa Fgf20 Gna12 Pak4 Pik3r5 Mapk1 Mos Mapk3 Mapk4 Cfl2 Actb Pip4k2b Pfn1 Pip4k2a Arhgef6 Arhgef1 Myh10 Nckap1 Slc9a1 Actg1 Ssh3 Ssh2 Raf1 Ssh1 Mylk Arpc5 Rhoa Enah Baiap2 Git1 Fgf23 Rassf7 Gna13 Fgd1 Vcl Bcar1 Csk Pik3cg Tmsb4x Arhgap35 Pik3cd Wasf2 Gsn Apc Limk1 Rock1 Pik3c2a Pip5k1b Chrm1 Pik3c2g Pip5k1a Chrm5 Chrm4 Pik3c3 Ins1 Sos2 Crk Sos1 Pik3r2 Ezr F2 Arhgef7 Pdgfra Rras2 Wasf1 Map2k1 Egf Cfl1 Pik3c2b Rac1 Cdc42 Pxn Dock1 Pak1 Itga1 FRUCTOSE METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260910%WP3894%RATTUS NORVEGICUS Fructose metabolism in proximal tubules Akr1b1 Slc2a5 Tpi1 Naglt1 Tkfc Fbp1 Aldob Gpi Aldoa Psme3 Slc5a10 Sord Pfkl Pfkp Slc5a9 Khk G6pc1 Hk1 GLUTATHIONE METABOLISM%WIKIPATHWAYS_20260910%WP469%RATTUS NORVEGICUS Glutathione metabolism Gclm Ggt5 Gss Gstm6 Gstm3 Gstm2 Anpep G6pdx Gstt1 Ggt1 Oplah Gstt2 Gpx3 PEPTIDE GPCRS%WIKIPATHWAYS_20260910%WP131%RATTUS NORVEGICUS Peptide GPCRs Agtr2 Bdkrb2 Cxcr1 Ednra Gnrhr Ntsr1 Fshr Ccr5 Ccr2 Cckbr Tacr1 Sstr2 Ghsr Cckar Ednrb Npy1r Npy5r Ntsr2 Brs3 Mc2r Oprd1 Cxcr4 Ccr7 Cxcr6 Oprl1 Ccr6 Ccr3 Galr2 Galr3 Galr1 Grpr Npy4r Lhcgr Sstr5 Sstr4 Sstr3 Sstr1 Avpr1b Mc5r Oprm1 Tacr3 Tacr2 Fpr1 Fpr3 C3ar1 Nmbr Fpr2 Bdkrb1 Tshr Ccr10 Mc4r Tac4 Oxtr Npy2r Mc3r Oprk1 Agtr1 CFTR ACTIVITY IN THE PLASMA MEMBRANE%WIKIPATHWAYS_20260910%WP1488%RATTUS NORVEGICUS CFTR activity in the plasma membrane Prkaa2 Plcb3 Plcb2 Plcb1 Snap23 Prkcg Cftr Nherf1 Ezr Ppp2ca Rack1 Plcz1 Prkaca Nherf2 Pdzk1 OXIDATIVE PHOSPHORYLATION%WIKIPATHWAYS_20260910%WP1283%RATTUS NORVEGICUS Oxidative phosphorylation Atp5me Ndufv1 Ndufv3 Atp5f1a Ndufa10l1 Ndufab1 Ndufc1 Coxfa4 Ndufc2 Ndufa5 Gzmb Atp5pb Gzmc Ndufa9 Ndufa8 Atp5pf Ndufb10 Atp5po Ndufs2 Ndufs5 Ndufs4 Ndufs6 Mt-co3 Ndufs8 Mt-nd5 Adck2 Mt-nd4 Ndufb2 Mt-atp6 Mt-nd6 Atp5mc1 Mt-nd1 Mt-nd3 Mt-nd4l Mt-nd2 Ndufb8 Ndufb7 Atp5mc3 Atp5mf NUCLEAR FACTOR ERYTHROID DERIVED 2 LIKE 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP2376%RATTUS NORVEGICUS Nuclear factor erythroid derived 2 like 2 signaling pathway Pik3ca Tp53 Prkd3 Eif2ak3 Ube2k Gstk1 Herpud1 Sqstm1 Fth1 Acta2 Prdx1 Abcc4 Vcp Txn Pmf1 Gstm5 Gstm4 Ubb Pik3r1 Slc1a4 Pik3r3 Mafk Actg2 Fosl1 Bach1 Dhcr7 Jun Akr1a1 Slc35b1 Dnajc5 Aldh3a1 Ftl1 Xpo1 Gsto1 Gsto2 Mgst2 Abcc1 Cbr1 Gstp1 Pik3r6 Taldo1 Dnajb4 Actc1 Nqo2 Fmo1 Akr1b10 Prkcg Brca1 Nras Usp14 Rras Ran Nqo1 Gstm1 Crebbp Mafg Ugdh Hmox1 Gclm Cdkn1a Nfe2l2 Pik3r5 Mapk9 Sod3 Mapk8 Sod2 Mapk1 Gstt2 Mgst1 Acta1 Mapk3 Prkce Actb Prkcq Scarb1 Prkci Prkcb Actg1 Prkcd Prkca Mapk7 Raf1 Sod1 Prkcz Pik3cd Pik3c2a Pik3c2g Gss Gstm6 Gstm3 Gstm2 G6pdx Gstt1 Abcc3 Pik3c3 Slc2a1 Gsk3b Fyn Pik3r2 Map2k7 Rras2 Map2k1 Map3k7 Map2k6 Pik3c2b Psmc6 Psmc5 Ldhb Psmc2 Mapk14 Psmc4 Psmc3 Map3k1 Aldoa Akr7a3 Akr7a2 Ephx1 Hras ACETATE MEDIATED PROMOTION OF METABOLIC SYNDROME%WIKIPATHWAYS_20260910%WP3650%RATTUS NORVEGICUS Acetate mediated promotion of metabolic syndrome Gast Ins2 MYOMETRIAL RELAXATION AND CONTRACTION PATHWAYS%WIKIPATHWAYS_20260910%WP140%RATTUS NORVEGICUS Myometrial relaxation and contraction pathways Nfkb1 Itpr3 Itpr1 Nos3 Jun Gsto1 Actc1 Il6 Prkcg Prkd1 Ets2 Rxfp1 Rgs4 Rgs5 Rgs2 Rgs3 Rgs1 Crcp Rgs9 Rgs6 Rgs7 Plcg2 Myl4 Mylk2 Myl2 Rxfp2 Atf5 Atf3 Maff Pkib Calca Grk5 Grk4 Atf6b Gnaq Pkia Grk6 Pkig Gngt1 Gucy1a1 Dgkz Gnb2 Gnb1 Gnb4 Gnb3 Rln1 Gng13 Ryr2 Atp2a3 Atp2a2 Oxt Adm Prkacb Ywhah Ywhag Ywhae Adcy3 Camk2a Adcy4 Adcy2 Guca2b Adcy7 Guca2a Crhr1 Adcy5 Creb3 Adcy9 Cald1 Pde4b Prkar1a Arrb2 Rgs20 Arrb1 Camk2g Rgs17 Camk2d Igfbp3 Gng3 Rgs19 Gng2 Lpar1 Igfbp4 Vkorc1l1 Rgs14 Gng7 Acta1 Igfbp1 Rgs16 Pde4d Gng8 Prkar2b Rgs10 Ackr5 Corin Ramp3 Camk2b Prkce Actb Prkcq Prkch Prkcb Actg1 Crh Prkcd Prkca Ywhaq Ywhab Gja1 Nos1 Prkcz Plcg1 Fos Prkar1b Gabpa Il1b Oxtr Atf2 Plcb3 IL 1 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP355%RATTUS NORVEGICUS IL 1 signaling pathway Il1rap Peli1 Akt1 Irak4 Nfkb1 Irak3 Irak2 Tollip Capn1 Elp1 Rela Sirpa Il1a Capns1 Sqstm1 Il1b Tab1 Traf6 Il1rn Il1r1 Ptpn11 Nfkbib Prkcz Map2k1 Nfkbia Map3k7 Chuk Map3k14 Mapk8 Mapk1 Mapk3 Il1r2 Plcg1 CHOLESTEROL METABOLISM%WIKIPATHWAYS_20260910%WP632%RATTUS NORVEGICUS Cholesterol metabolism Srebf1 Apoc1 Lpl Scarb1 Hmgcr Fdps Apoe Idi1 Mvk Rusc1 Apoc2 Fdft1 Lss Hmgcs1 Mvd Msmo1 Soat1 Dhcr7 OSTEOBLAST SIGNALING%WIKIPATHWAYS_20260910%WP227%RATTUS NORVEGICUS Osteoblast signaling Slc34a1 Bglap Pth Pdgfra Fgf23 Tnfsf11 Col1a1 Pdgfrb TNF ALPHA NF KB SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP457%RATTUS NORVEGICUS TNF alpha NF kB signaling pathway Tnfrsf1a Akt1 Psmd3 Nfkb1 Ptk2 Rela Fadd Tnf Nfkbib Casp7 Casp3 Casp2 Nfkbia Chuk Flna Hdac1 Nr2c2 Tab2 Traf6 Crebbp Nfkb2 Ywhah Ywhag Ywhae Map3k8 Prkaca Akt2 Elp1 Map3k3 Map3k2 Ywhab Ppp2ca Rack1 Nkiras1 Nkiras2 Rps6kb1 Tbkbp1 Rps11 Rpl6 Rps13 Prkcz Pias3 Fbl Rpl30 Ube2i Dpf2 Kcnq1 Polr1b Rnf216 Polr1a Polr1g Fbxw11 Polr1e Casp8ap2 Txlna Tank Gtf2i Actl6a Smarce1 Tifa Ube2d2 Polr2sl1 Btrc Nfkbiz Glg1 Bag4 Ripk2 Ripk3 G3bp2 Dcaf7 Cops3 Cav1 Gab1 Capn3 Kpna6 Mcc Kpna3 Kpna2 Gsk3b Dap Cul1 Rel Ccar2 Traf4 Mcm7 Pfdn2 Faf1 Csnk2a1 Tnfrsf8 Mark2 Hdac2 Smarcb1 Alpl Rasal2 Akap8 Csnk2b Rpl8l1 Cyld Fkbp5 Mcm5 Ptpn11 Tnip2 Tnip1 Pdcd2 Nsmaf Zfand5 Commd1 Trpc4ap Fancd2 Ktn1 Pebp1 Pkn1 Lrpprc Mtif2 Map3k14 Tradd Hspb1 Traf2 Psmc2 Ripk1 Psmc3 Map3k1 Psmd12 Psmd13 Src Ikbkb Ikbkg Psmb5 Psmd6 Tnfrsf1b ESTROGEN SIGNALING%WIKIPATHWAYS_20260910%WP1279%RATTUS NORVEGICUS Estrogen signaling Cdk7 Akt1 Taf7 Nfkb1 Taf6 Taf5 Shc2 Jun Chuk Brca1 Hdac1 Fos Ccnd1 Gngt1 Crebbp Hdac2 Sos1 Braf Esr1 Gnb1 Map2k1 Elk1 Ilk Mnat1 Hdac3 Hdac5 Taf13 Taf12 Gtf2f2 Tbp Mapk14 Mapk9 Ccnh Gtf2b Gtf2e1 Polr2c Mapk1 Polr2a Polr2b Taf9 Polr2g Grb2 Polr2h Src Polr2f Polr2i Hras Ikbkb Polr2j Gtf2h2 Gtf2h1 Prkaca Gtf2h4 Gtf2h3 Ercc3 Gper1 GLYCOGEN METABOLISM%WIKIPATHWAYS_20260910%WP160%RATTUS NORVEGICUS Glycogen metabolism Gyg1 Gsk3b Gbe1 Calm3 Phkb Gsk3a Ppp2r3a Ppp2r5b Calm2 Ppp2r5a Ppp2r2c Ppp2r2b Phka1 Phka2 Ppp2cb Pygb Phkg1 Phkg2 Agl Ppp2r2a Ptpa Ppp2ca Ppp2r1a Ugp2 Pgm1 Gys1 Gys2 SULINDAC METABOLIC PATHWAY%WIKIPATHWAYS_20260910%WP2541%RATTUS NORVEGICUS Sulindac metabolic pathway Msra Msrb2 Cyp1a1 STRIATED MUSCLE CONTRACTION%WIKIPATHWAYS_20260910%WP316%RATTUS NORVEGICUS Striated muscle contraction Tnni3 Tnni2 Tnni1 Tnnc2 Tnnc1 Tmod1 Myh3 Actn3 Mybpc3 Actc1 Actn4 Myl9 Acta2 Actg1 Vim Acta1 Tnnt3 Tnnt2 Tnnt1 Tpm4 Tpm3 Tpm2 Neb Myl2 IL 6 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP135%RATTUS NORVEGICUS IL 6 signaling pathway Akt1 Nfkb1 Ptk2b Ptk2 Stat3 Ppp2r3a Cd40 Ppp2r5b Ppp2r5a Ppp2r2c Ppp2r2b Ppp2cb Prkcd Raf1 Socs3 Pik3r1 Ppp2r2a Ptpa Eif4ebp1 Ppp2ca Ppp2r1a Gab2 Rps6kb1 Jun Casp9 Bad Casp3 Bmx Ppp2r3b Hsp90aa1 Il6 Foxo4 Cdk5r1 Ppp2r5c Il6r Cdk9 Ppp2r5e Cdk5 Hdac1 Nlk Foxo3 Foxo1 Tmem97 Stat5a Gab1 Stat5b Plcg1 Fos Hnf1a Fgr Eif4e Gsk3b Hck Btk Erbb2 Rps6ka2 Il6st Fyn Lyn Crebbp Sos1 Pik3r2 Tec Sgk1 Fes Cebpb Ncoa1 Rb1 Mapt Ptpn11 Inppl1 Shc1 Map2k2 Map2k1 Map3k7 Map2k6 Hspb1 Rac1 Mapk14 Mapkapk2 Jak2 Mapk8 Jak1 Map2k4 Mapk1 Grb2 Daxx Mapk3 Hras Pxn Map3k4 FOCAL ADHESION%WIKIPATHWAYS_20260910%WP188%RATTUS NORVEGICUS Focal adhesion Pik3ca Akt1 Hgf Ptk2 Itgb1 Met Pak6 Pak3 Pak2 Pak5 Pik3r1 Vegfc Vegfb Jun Bad Igf1r Comp Ppp1r12a Tnn Kdr Tnr Igf1 Col1a2 Lama5 Pdgfrb Reln Lama3 Lama4 Mylk2 Thbs1 Tln1 Thbs4 Blk Vasp Srms Txk Pdgfc Chad Itga8 Itga6 Itga9 Erbb2 Vtn Itga3 Egfr Pdgfb Itga10 Ccnd2 Cav3 Cav2 Braf Tesk2 Tnk2 Ptk6 Col4a6 Ibsp Pelo Pdgfa Itgax Itgav Itgam Col1a1 Itgae Itgal Diaph1 Itgad Itgb8 Itgb6 Pak4 Itga2b Itgb5 Itgb2 Actn1 Itgb3 Col11a2 Lamb3 Pik3r5 Spp1 Lamb1 Col6a2 Map2k3 Styk1 Zyx Lamc1 Mapk9 Pip5k1c Mapk8 Mapk1 Mapk4 Akt2 Actb Capn1 Actg1 Mapk7 Raf1 Shc3 Mylk Vcl Bcar1 Pik3cg Pik3cd Rock1 Pdpk1 Rac2 Cav1 Fgr Ccnd1 Gsk3b Hck Col4a1 Fyn Crk Rock2 Sos1 Pik3r2 Pdgfra Col11a1 Tnc Mapk12 Shc1 Vegfd Pten Selenop Map2k2 Vwf Map2k1 Elk1 Egf Rapgef1 Col5a1 Col4a2 Map2k6 Ilk Pgf Thbs2 Rac1 Cdc42 Mapk14 Akt3 Grb2 Src Hras Pxn Dock1 Pak1 Rap1a Rap1b STEROID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP66%RATTUS NORVEGICUS Steroid biosynthesis Hsd3b5 Hsd17b3 Hsd3b1 Hsd17b4 Hsd3b6 Hsd17b1 Hsd17b2 Cyp17a1 F13b Hsd17b7 AMINO ACID CONJUGATION OF BENZOIC ACID%WIKIPATHWAYS_20260910%WP1287%RATTUS NORVEGICUS Amino acid conjugation of benzoic acid Glyat IL 5 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP44%RATTUS NORVEGICUS IL 5 signaling pathway Il5 Akt1 Nfkb1 Ptk2b Stat3 Prkcb Prkcd Raf1 Shc2 Pik3r1 Alox5 Jun Pik3cg Nfkbia Bax Foxo3 Stat5a Stat5b Gsk3b Hck Btk Gsk3a Rps6ka1 Ptpn6 Lyn Pik3r2 Ptpn11 Itgam Syk Atf2 Shc1 Sh2b2 Pla2g4a Elk1 Itgb2 Rapgef1 Cdkn1b Rac1 Mapk14 Mapk9 Jak2 Jak1 Mapk1 Grb2 Rap1gap Ctnnb1 Mapk3 Hras Pim1 Sox4 Crkl Sdcbp Alox5ap Hcls1 Il5ra Unc119 TRYPTOPHAN METABOLISM%WIKIPATHWAYS_20260910%WP270%RATTUS NORVEGICUS Tryptophan metabolism Ddc Tph1 Aldh3a2 Aldh9a1 Inmt Cyp2j3 Hsd17b10 Cyp2b15 Wars1 Cyp2j4 Prmt1 Tdo2 Cyp4f1 Cyp2e1 Cyp2f2 Aadat Cyp7b1 Ogdh Aanat Afmid Gcdh Mdm2 Aoc1 Dhcr24 Haao Asmt Cyp2d26 Echs1 Kynu Cyp2a2 Cyp2a1 Ube3a Acmsd Ido1 Hadh Cat Cyp1a1 Aldh2 Cyp1b1 Aldh1a1 Acad10 VEGFR 3 SIGNALING%WIKIPATHWAYS_20260910%WP1964%RATTUS NORVEGICUS VEGFR 3 signaling Itpkc Flt4 Akt1 Nos3 Mapk1 Vegfc Grb2 Mapk3 Casp9 Bad Shc1 Pik3cg Vegfd Plcg1 TRANSLATION FACTORS%WIKIPATHWAYS_20260910%WP149%RATTUS NORVEGICUS Translation factors Etf1 Gspt2 Eif4e Cluh Eif2ak3 Eif4ebp1 Eef1a2 Eef1d Eif3j Pycr3 Eif2s3 Eif2ak1 Eef1g Eif2ak2 Eif4ebp2 Eif3f Eif4g1 Eif4g3 Eif3b Eif3a Eif1a Eif5b Eif5a Eif2b3 Eif2b2 Eif2b5 Eif2b4 Kcnq2 Eif2s2 Eef2k Eif2b1 Eif4h Eif1 Eif1ax Eif6 Eif4a2 Eif4a1 CATECHOLAMINE SYNTHESIS%WIKIPATHWAYS_20260910%WP513%RATTUS NORVEGICUS Catecholamine synthesis Ddc Pnmt Th Pah Dbh P53 SIGNAL PATHWAY%WIKIPATHWAYS_20260910%WP656%RATTUS NORVEGICUS p53 signal pathway Bax Fas Tp53 Ccnb3 Gadd45g Gtse1 Ccne1 Bbc3 Siah1 Perp Parp1 Pmaip1 Cdk1 Rprm Igfbp3 Mdm2 Bid Igf1 Casp9 Casp3 GPCRS CLASS C METABOTROPIC GLUTAMATE PHEROMONE%WIKIPATHWAYS_20260910%WP42%RATTUS NORVEGICUS GPCRs class C metabotropic glutamate pheromone Gprc5b Gprc5a Casr Gprc5d Gprc5c Grm3 Grm2 Grm4 Grm7 Gabbr1 Grm6 Gabbr2 Grm1 Grm5 Grm8 EPO RECEPTOR SIGNALING%WIKIPATHWAYS_20260910%WP1284%RATTUS NORVEGICUS EPO receptor signaling Map2k2 Map2k1 Akt1 Stat3 Pdk1 Sos1 Jak2 Raf1 Mapk1 Irs2 Epo Grb2 Src Rasa1 Mapk3 Ptprc Ptpru Stat5a Shc1 Stat5b Pik3cg TNF ALPHA AND MUCUS PRODUCTION IN LUNG EPYTHELIUM%WIKIPATHWAYS_20260910%WP1487%RATTUS NORVEGICUS TNF alpha and mucus production in lung epythelium Tgfa Tnfrsf1a Map2k1 Nfkbia Nfkb1 Chuk Rela Tradd Rps6ka2 Traf2 Tlr4 Egfr Il6 Sos1 Raf1 Mapk1 Grb2 Tnf Ikbkb Ripk2 Ikbkg Muc2 Shc1 INFLAMMATORY RESPONSE PATHWAY%WIKIPATHWAYS_20260910%WP40%RATTUS NORVEGICUS Inflammatory response pathway Il2ra Tnfrsf1a Il5 Il2rb Il2rg Cd40lg Cd40 Lamb1 Vtn Lamc1 Il2 Il4 Col1a2 Ifng Col1a1 Lama5 Lck Cd86 Il4r Tnfrsf1b Cd80 Il5ra Thbs1 Cxhxorf65 RELATIONSHIP BETWEEN GLUTATHIONE AND NADPH%WIKIPATHWAYS_20260910%WP2562%RATTUS NORVEGICUS Relationship between glutathione and NADPH Tp53 Fth1 Anpep Txn Alox5 Casp3 Ftl1 Gsn Bax Abcc1 Fas Gstp1 Taldo1 Dffa Gss Dffb G6pdx Nqo1 Gpi Pgm2 Pfkl Eno1 Ugp2 Ugdh Pgm1 Pgam2 Nnt Ptgr1 Gclm Cdkn1a Map3k5 Kif1b Pgd Tfr2 Gapdh Tkt Gapdhl6 Rpe Dpep2 Rpia Ugt8 Pklr Ltc4s Mapk8 Tfrc Gck Aldoa Pgls Pgk1 WNT MYOFIBROBLASTIC ACTIVATION OF HEPATIC STELLATE CELLS%WIKIPATHWAYS_20260910%WP3649%RATTUS NORVEGICUS Wnt myofibroblastic activation of hepatic stellate cells Pparg Wnt3a PENTOSE PHOSPHATE PATHWAY%WIKIPATHWAYS_20260910%WP282%RATTUS NORVEGICUS Pentose phosphate pathway Pgls Kif1b Taldo1 Pgd Tkt Rpe Rpia G6pdx BRAIN DERIVED NEUROTROPHIC FACTOR%WIKIPATHWAYS_20260910%WP2148%RATTUS NORVEGICUS Brain derived neurotrophic factor Map2k1 Raf1 Mapk1 Plat Plg Ntrk2 Serpine1 Ngfr Bdnf EBV LMP1 SIGNALING%WIKIPATHWAYS_20260910%WP1278%RATTUS NORVEGICUS EBV LMP1 signaling Nfkb1 Map3k7 Chuk Map3k14 Rela Tradd Ifnb1 Traf6 Mapk8 Mapk1 Pdlim7 Ccl5 Nfkb2 Ikbkb NUCLEOTIDE GPCRS%WIKIPATHWAYS_20260910%WP502%RATTUS NORVEGICUS Nucleotide GPCRs Adora2b P2ry6 Adora2a Lpar6 Adora1 P2ry2 P2ry1 Lpar4 PROXIMAL TUBULE TRANSPORTERS%WIKIPATHWAYS_20260910%WP3881%RATTUS NORVEGICUS Proximal tubule transporters Atp1a1 Fxyd4 Slc22a5 Tctn2 Atp6v0a2 Atp6v0a4 Atp6v1e1 Atp6v1g3 Atp6v0e2 Atp6v0a1 Slc1a1 Atp6v0c Car7 Slc4a4 Slc38a7 Slc6a19 Slc7a6 Slc7a7 Atp1b1 Nherf1 Slc9a3 Slc9a8 Slc13a3 Slc34a1 Slc7a8 Atp6v1a Slc13a1 Slc7a9 Slc34a2 Slc13a2 Nherf2 Atp6v1b2 Atp6v0d2 Atp6v0d1 Atp6v1b1 Slc16a10 Atp6v1g1 Ca2 Ca4 Slc22a8 Atp6v1d Ca14 Atp6v1h Slc20a2 Slc22a6 Car15 Slc26a1 ID SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP397%RATTUS NORVEGICUS ID signaling pathway Nfkb1 Atf3 Psmd4 Rela Rbl2 Ccne1 Rbl1 Smad4 Rb1 Ngf Lck Id1 Elk1 Egf Cd40lg Elk4 Igf1r Srebf1 Myog Ccna2 Myod1 Id2 Id4 Tcf7l2 Bmp6 Pax2 Id3 Smad1 Pax8 Tert Smad5 Myf5 Kdr Hes1 Igf1 Bmp2 BETA OXIDATION META PATHWAY%WIKIPATHWAYS_20260910%WP372%RATTUS NORVEGICUS Beta oxidation meta pathway Pnpla2 Acsl1 Tpi1 Gpd2 Acsl3 Lpl Hadha Lipe Hadhb Dld Acadm Gcdh Crat Cpt2 Acads Acadvl Echs1 Cpt1a Lipf Acsl5 Acsl6 Acsl4 Acat1 Hadh HEDGEHOG SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP574%RATTUS NORVEGICUS Hedgehog signaling pathway Hhip Igf2 Gli1 Gli3 Gli2 Ski Shh Ptch2 Ptch1 Sufu Sap18 Dyrk1a Smo Cdk1 Crebbp Ccnb1 P53 PATHWAY%WIKIPATHWAYS_20260910%WP655%RATTUS NORVEGICUS p53 pathway Tp53 Tsc2 Ccne1 Cycs Siah1 Sesn1 Perp Chek2 Zmat3 Pmaip1 Cdk1 Rprm Serpinb5 Gadd45a Cdkn2a Shisa5 Sfnl1 Adgrb1 Cd82 Cdk6 Mdm4 Ppm1d Bid Rchy1 Tp73 Casp9 Chek1 Casp3 Pten Bax Fas Cdkn1a Serpine1 Ccng1 Igfbp3 Ccnb1 IL 9 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP8%RATTUS NORVEGICUS IL 9 signaling pathway Map2k1 Akt1 Il2rg Stat3 Vcp Jak1 Socs3 Mapk1 Irs2 Pik3r1 Grb2 Mapk3 Kat5 Ptpn11 Il9 Jak3 Il9r Stat5a Shc1 Stat5b Cxhxorf65 MRNA PROCESSING%WIKIPATHWAYS_20260910%WP529%RATTUS NORVEGICUS mRNA processing Celf1 Prpf4 Phf5a Prpf6 Prpf3 Prpf40a Scamp3 Hnrnpa2b1 Supt5h Cdc40 Rnmt Snrnp70 Clp1 Snrpb2 Xrn2 Spop Prpf8 Snrnp40 Prpf18 Hnrnpr Dhx9 Hnrnpu Papola Snrpb Snrpa1 Snrpa Clk2 Clk3 Clk4 Mettl3 Prp4k Ptbp1 Fus Sugp1 Sugp2 Srpk1 Cpsf1 Hnrnpd Cpsf2 Cpsf3 Ddx1 Snrpepl2 Hnrnpk Hnrnpm Hnrnpab Cstf1 Ybx1 Clasrp Prmt1 Nudt21 Tmed10 Sfpq Prmt2 Cstf2 Dhx16 Cstf3 Srsf1 Ptbp2 Srsf9 Srsf7 Srsf6 Srsf5 Srsf4 Srsf3 Srsf2 Srek1 Srsf10 Srrm1 Rbm17 U2af1 Nxf1 Sf3a1 Sf3a2 Sf3a3 U2af2 Ncbp2 Ncbp1 Cd2bp2 Rbmx Snrpd1 Tra2b Celf4 Celf2 Pabpn1 Snrpd3 Sf3b2 Sf3b3 Sf3b4 Rbm39 Sfswap Sf3b5 Srp54 Hnrnph2 Ppm1g Hnrnph1 Dicer1 Ddx20 Rngtt Smc1a GPCRS CLASS A RHODOPSIN LIKE%WIKIPATHWAYS_20260910%WP473%RATTUS NORVEGICUS GPCRs class A rhodopsin like Agtr2 Cysltr1 Ackr4 Gpr4 Gpr3 Ackr2 Gpr6 P2ry10 Or2ag1 P2ry12 P2ry14 F2rl1 Or10a4 Gpr50 F2rl2 Mas1 F2rl3 Adora2a Cxcr1 Ednra Ntsr1 Htr7 Fshr Htr2a Ccr5 Ccr2 Adra1d Cckbr Sstr2 Htr1f C5ar2 F2r Or3a1e Chrm3 Chrm2 Or2f1 Drd3 Gpr18 Grpr P2ry13 Gpr17 Adora2b Mtnr1a Cnr1 Cnr2 Ptgdr Ptgir Ptger4 Ptgfr Ptger2 Ptafr Ptger3 Ptger1 Bdkrb2 Drd1 Drd4 Adra1a Htr2c Htr1a Adra2a Adra2c Adra2b Htr4 Chrm1 Hrh1 Htr6 Chrm5 Chrm4 Hrh2 Adrb1 Drd5 Adra1b Adrb3 Htr1d Ghsr Htr5a Cckar Ednrb Npy1r Npy5r Ntsr2 Brs3 Mc2r Oprd1 Cxcr4 Ccr7 Hcar1 Oprl1 Gpr161 Ccr6 Rrh Ccr3 Or3a1 Galr2 Or2h2 Galr3 Gpr65 Galr1 Or2h1 Npy4r Gpr68 Lhcgr Gpr63 Sstr5 Gpr173 Sstr4 Gpr174 Sstr3 Gpr171 Sstr1 Cmklr1 Avpr1b Olr226 Mc5r Oprm1 Gpr75 Tbxa2r Or7c70 Ffar3 Fpr1 Aplnr Fpr3 C3ar1 Nmbr Ffar1 Fpr2 Ffar2 Bdkrb1 Or2b2 Or2j3 Ccr10 Hrh3 Or5v1b Mc4r Gpr85 Or7a36 Oxtr Opn4 Npy2r Xcr1 Mc3r Lpar5 Oprk1 Opn3 Olr1073 Gpr19 Sucnr1 Or6b1 Gpr15 Or2c1 Or13c7d Gpr12 Adora3 Or2t1 Opn1sw Npbwr1 Nmur2 Prlhr Gpr25 Gpr27 Gpr22 Gpr21 Ccr9 Mchr1 Gpr37 Gpr39 Or11a4 Rgr Or14j1 Or10j27 P2ry6 Npffr1 Lpar6 Or2f2 Adora1 Npffr2 P2ry2 Ptgdr2 P2ry1 Rho Lpar4 Hcrtr1 Or5ap2b Or2w1 Gpr37l1 Gper1 Agtr1 Cysltr2 INTEGRIN MEDIATED CELL ADHESION%WIKIPATHWAYS_20260910%WP74%RATTUS NORVEGICUS Integrin mediated cell adhesion Akt2 Akt1 Ptk2 Itgb1 Pak6 Capn1 Pak3 Capns1 Pak2 Vav3 Itgb4 Mapk7 Raf1 Itga2 Shc3 Capn9 Git2 Capn5 Capn7 Capn2 Vcl Bcar1 Rock1 Mapk10 Pdpk1 Rac2 Mylk2 Cav1 Tln1 Capn3 Vav2 Vasp Itga8 Itga6 Itga9 Itga3 Fyn Itga10 Crk Rock2 Sos1 Cav3 Braf Pik3r2 Cav2 Itgax Itgav Arhgef7 Itgam Itgae Itgal Mapk12 Itgad Itgb8 Shc1 Itgb6 Pak4 Selenop Itga2b Map2k2 Itgb5 Map2k1 Itgb2 Rapgef1 Capn6 Itgb3 Map2k6 Ilk Map2k3 Rac1 Cdc42 Zyx Akt3 Mapk1 Grb2 Src Hras Mapk4 Pxn Dock1 Rho Pak1 Itga1 Rap1a Rap1b WNT SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP375%RATTUS NORVEGICUS Wnt signaling pathway Akt1 Camk2b Prkcb Prkca Raf1 Rhoa Ppp2ca Wnt5a Cdh1 Tax1bp3 Skp1 Sfrp2 Jun Sfrp1 Sox9 Dkk1 Magi3 Axin1 Axin2 Ror2 Crybb2 Apc Csnk1d Sall1 Cdc25c Senp2 Lef1 Ruvbl1 Vangl2 Lrp6 Csnk1a1 Dab2 Prkcg Lrp5 Tfap2a Pax2 Dvl1 Wnt7a Brd7 Wnt4 Ctbp1 Wnt3 Ctbp2 Fzd2 Jup Btrc Fzd4 Dvl2 Map1b Nlk Fzd9 Fzd8 Dvl3 Ctnnbip1 Ankrd6 Bcl9 Tmem97 Dlg1 Dlg2 Dlg4 Tcf4 Hipk2 Gsk3b Ccnd1 Cul1 Csnk2a1 Cdk1 Mark2 Smad4 Csnk2b Nr5a1 Wnt2 Camk2a Map3k7 Arrb2 Rac1 Arrb1 Camk2g Tbp Mapk9 Camk2d Mapk8 Mapk1 Wnt3a Ctnnb1 Mapk3 Mapk8ip1 G1 TO S CELL CYCLE CONTROL%WIKIPATHWAYS_20260910%WP348%RATTUS NORVEGICUS G1 to S cell cycle control Cdk7 Tp53 Ccnb1 Ccna1 Ccne2 Necab3 Cdkn2b Ccnd1 Tfdp1 Cdkn2c Cldn5 Pcna Myt1 Atf6b Mcm7 Ccne1 Rbl1 Mcm4 Mcm6 Mcm2 Pole2 Pola2 Cdk1 Ccng2 Creb3l4 Gadd45a Creb3l1 Orc5 E2f5 Rpa3l1 Mdm2 Orc4 Orc6 Cdk6 Orc1 Orc3 Rb1 Rpa2 Mcm5 Wee1 E2f2 E2f3 E2f4 E2f6 Pole Cdkn1c E2f1 Cdkn1a Creb3 Mnat1 Cdkn1b Ccnh ATM SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP654%RATTUS NORVEGICUS ATM signaling pathway Ccnd1 Necab3 Bax E2f1 Tp53 Cdkn1a Ccne1 Cycs Chek2 Brca1 Pmaip1 Cdk1 Rprm Gadd45a Sfnl1 Cdk6 Rb1 Bak1 Casp9 Casp3 Ccnb1 TOLL LIKE RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP1309%RATTUS NORVEGICUS Toll like receptor signaling pathway Pik3ca Akt2 Akt1 Nfkb1 Tollip Cd40 Rela Irf3 Irf7 Irf5 Fadd Pik3r1 Pik3r3 Tnf Jun Pik3cg Pik3cd Nfkbia Chuk Tlr4 Mapk10 Cxcl10 Il6 Fos Tab2 Cd14 Il1b Traf6 Pik3r2 Map2k7 Nfkb2 Cd86 Mapk13 Cd80 Il12b Il12a Ticam2 Map2k1 Lbp Ly96 Map3k7 Tlr1 Ifna4 Map2k6 Ifna1 Pik3r5 Tlr8 Spp1 Tlr7 Tlr6 Cxcl9 Ifnb1 Tlr5 Map2k3 Rac1 Tlr3 Tlr2 Cxcl11 Mapk14 Mapk9 Akt3 Ifnar1 Ccl4 Ripk1 Mapk8 Ccl3 Map2k4 Mapk1 Map3k8 Ccl5 Mapk3 Ikbkb Ikbkg PROSTAGLANDIN SYNTHESIS AND REGULATION%WIKIPATHWAYS_20260910%WP303%RATTUS NORVEGICUS Prostaglandin synthesis and regulation Tbxas1 Ptgis Cyp11a1 Hsd11b1 Hsd11b2 Ednra Ptgds Pla2g4a Ptgdr Ptgir Ptger4 Ptgfr Ptger2 Anxa1 Anxa8 Ptger3 Anxa6 Ptger1 Ednrb Prl S100a6 Scgb1a1 Edn1 Hpgd Anxa5 Anxa4 Anxa3 S100a10 Ptgs1 Ptgs2 OSTEOCLAST%WIKIPATHWAYS_20260910%WP489%RATTUS NORVEGICUS Osteoclast Ctsk Itgb3 Atp6v1e1 Spp1 Tnfsf11 Ifnb1 Slc9a1 Trpv5 Ifnar1 Zcchc2 G13 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP520%RATTUS NORVEGICUS G13 signaling pathway Arhgdib Iqgap2 Ppp1cb Cfl2 Wasl Sh3rf1 Cit Cyfip1 Mybph Pip4k2a Pak3 Arhgef1 Rock2 Pik3r2 Tnk2 Rps6kb1 Diaph1 Pik3cd Limk1 Pkn1 Rock1 Rac1 Mapk10 Cdc42 Map3k4 FATTY ACID BIOSYNTHESIS%WIKIPATHWAYS_20260910%WP504%RATTUS NORVEGICUS Fatty acid biosynthesis Acsl1 Scd1 Acsl3 Mecr Echdc3 Echdc1 Echdc2 Acaa2 Fasn Acacb Acaca Decr1 Acly Echs1 Pc Acsl5 Acsl6 Hadh ACETYLCHOLINE SYNTHESIS%WIKIPATHWAYS_20260910%WP360%RATTUS NORVEGICUS Acetylcholine synthesis Ache Pcyt1a Ahsg Pdha1 Chat Pemt GPCRS CLASS B SECRETIN LIKE%WIKIPATHWAYS_20260910%WP378%RATTUS NORVEGICUS GPCRs class B secretin like Vipr1 Calcrl Glp1r Crhr2 Crhr1 Adgrl2 Adgrl3 Ghrhr Calcr Adgre5 Gipr Gcgr Adgre1 Sctr Adgrl4 Adcyap1r1 Adgrl1 Glp2r THICK ASCENDING LIMB TRANSPORTERS%WIKIPATHWAYS_20260910%WP3882%RATTUS NORVEGICUS Thick ascending limb transporters Atp1a1 Ca2 Ca4 Slc4a7 Slc12a1 Kcnq1 Slc9a2 Aqp1 Kcnk12 Slc12a7 Kcnj16 Clcnkb Clcnka Atp1b1 Slc9a3 SELENIUM METABOLISM SELENOPROTEINS%WIKIPATHWAYS_20260910%WP1293%RATTUS NORVEGICUS Selenium metabolism selenoproteins Nfkb1 Rela Gpx3 Gpx6 Msrb1 Selenow Jun Txnrd2 Selenop Rpl30 Selenok Nfe2l2 Selenbp1 Eefsec Crem Sp3 Selenof Sars2 Selenoi Sars1 Fabp1 Selenoo Selenos Dio1 Selenot Dio2 Dio3 Selenov Sephs1 Trnau1ap Fos HYPERTROPHY MODEL%WIKIPATHWAYS_20260910%WP442%RATTUS NORVEGICUS Hypertrophy model Zeb1 Dusp14l1 Eif4e Ifrd1 Atf3 Ccn1 Nr4a3 Myog Il1a Il1r1 Eif4ebp1 Jund Ifng Ankrd1 Hbegf Wdr1 IL 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260910%WP569%RATTUS NORVEGICUS IL 2 signaling pathway Pik3ca Akt1 Nfkb1 Ptk2b Stat3 Rela Ybx1 Raf1 Socs3 Pik3r1 Rack1 Gab2 Lck Rps6kb1 Pik3cg Prkcz Pik3cd Chuk Nr3c1 Eif3b Il2 Ets2 Tert Foxo3 Stat5a Stat5b Eif4e Stam2 Cd53 Itm2b Stam Nmi Ptpn6 Fyn Crk Lyn Sos1 Pik3r2 Mtor Ptpn11 Jak3 Syk Shc1 Cxhxorf65 Il2ra Map2k1 Il2rg Plcb1 Mapk14 Mapk9 Mapkapk2 Jak2 Mapk8 Jak1 Mapk1 Irs2 Mknk1 Grb2 Mapk3 Crkl ANGIOTENSIN II SIGNALING ACUTE IN THICK ASCENDING LIMBS%WIKIPATHWAYS_20260910%WP3887%RATTUS NORVEGICUS Angiotensin II signaling acute in thick ascending limbs Agtr2 Akt2 Akt1 Agtr1b Calm3 Calm2 Gnaq Pde2a Agtrap Nox4 Mas1 Itpr3 Prkca Itpr2 Itpr1 Nos3 Dnm1 Pten Arrb2 Prkcg Akt3 Pdpk1 Prkaca Plcg2 Plcg1 Agtr1 METAPATHWAY BIOTRANSFORMATION%WIKIPATHWAYS_20260910%WP1286%RATTUS NORVEGICUS Metapathway biotransformation Nat1 Nat2 Ephx2 Gal3st4 Gal3st3 Inmt Nat9 Hnmt Gstk1 Cyp2e1 Chst11 Cyp2f2 Cyp7b1 Gstm5 Gstm4 Cyp26b1 Akr1a1 Gsto1 Cyp26a1 Gstp1 Cyp27b1 Gss Fmo1 Akr1b10 Cyp8b1 Cyp24a1 Cyp7a1 Sult1e1 Gstm1 Comt Sult1a1 Cyp1a1 Cyp1b1 Chst10 Chst12 Cyp2u1 Chst13 Cyp4f18 Chst14 Cyp4f17 Ugt2b1 Sult6b2 Naa40 Nat10 Ndst1 Cyp4x1 Ndst3 Hs3st3a1 Sult4a1 Chst1 Sult2a1 Chst3 Sult2a6 Chst4 Chst6 Chst9 Akr1c1 Akr1b1 Zfp628 Gstz1 Hs3st2 Sult1b1 Hs3st5 Hs3st6 Cyp2s1 Hs3st3b1 Gstm7 Cyp4f39 Baat Naa20 Akr1d1 Gstcd Kcnab2 Cyp51a1 Kcnab3 Akr7a3 Mgst1 Hs2st1 Akr7a2 Tpmt Cyp21a1 Cyp17a1 Glyat Fmo3 Ephx1 Fmo2 Fmo5 Hs6st3 Fmo4 Hs6st1 Sult2b1 Naa50 Cyp26c1 Cyp46a1 Nat8 G PROTEIN SIGNALING PATHWAYS%WIKIPATHWAYS_20260910%WP73%RATTUS NORVEGICUS G protein signaling pathways Prkce Prkd3 Pde7b Pde7a Akap7 Adcy8 Akap3 Prkcq Akap4 Arhgef1 Akap1 Gnaz Akap10 Prkci Slc9a1 Akap11 Prkcb Akap12 Prkcd Akap9 Prkca Akap13 Itpr1 Pde8a Pde8b Rhoa Kcnj3 Pakap Gna14 Gnao1 Gnal Gng5 Gna13 Pde4c Gnas Pde1c Pde1a Gng11 Prkcz Prkcg Nras Rras Ppp3cc Prkar1b Ppp3ca Gnaq Gngt1 Gnb2 Gnb1 Akap8 Gnb3 Gng13 Prkacb Adcy3 Adcy4 Gna12 Adcy2 Adcy7 Adcy5 Adcy9 Plcb3 Pde4b Prkar1a Gng3 Gnai1 Gnai3 Hras Pde4d Gng8 Prkar2b Prkaca WNT SIGNALING PATHWAY AND PLURIPOTENCY%WIKIPATHWAYS_20260910%WP1288%RATTUS NORVEGICUS Wnt signaling pathway and pluripotency Tp53 Prkce Ppp2r3a Prkcq Ppp2r2c Ppp2r2b Prkci Prkcb Ppp2cb Prkcd Prkca Rhoa Ppp2r2a Ptpa Ppp2ca Ppp2r1a Wnt5a Fosl1 Jun Wnt5b Pafah1b1 Axin1 Prkcz Sox2 Axin2 Wnt9b Fbxw2 Apc Wnt11 Tcf7 Nkd2 Wnt6 Lef1 Tcf7l1 Cd44 Pou5f1 Lrp6 Fzd3 Nanog Mapk10 Ppm1j Lrp5 Dvl1 Wnt7a Wnt4 Ctbp1 Wnt3 Ctbp2 Fzd2 Fzd4 Dvl2 Nlk Fzd9 Fzd8 Dvl3 Tmem97 Gsk3b Ccnd1 Ppard Ccnd2 Crebbp Wnt2 Map3k7 Mapk9 Wnt3a Plau Ctnnb1 MISMATCH REPAIR%WIKIPATHWAYS_20260910%WP1295%RATTUS NORVEGICUS Mismatch repair Pcna Pold1 Lig1 Msh2 Rfc1 INTERACTIONS BETWEEN CFTR AND OTHER ION CHANNELS%WIKIPATHWAYS_20260910%WP1485%RATTUS NORVEGICUS Interactions between CFTR and other ion channels Scnn1b Scnn1g Cftr Nherf1 POLYOL PATHWAY%WIKIPATHWAYS_20260910%WP1303%RATTUS NORVEGICUS Polyol pathway Aldob Akr1b1 Sord Khk