SEROTONIN AND ANXIETY%WIKIPATHWAYS_20260211%WP2132%RATTUS NORVEGICUS Serotonin and anxiety Grin2d Ppp3ca Nlgn1 Adra1a Arc Prkcb Plek Htr2a Crh Htr2c Fos Htr1a ID SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP397%RATTUS NORVEGICUS ID signaling pathway Lck Smad5 Igf1r Srebf1 Myf5 Atf3 Myog Ccna2 Flt1 Ccne1 Myod1 Elk1 Elk4 Id2 Cd40lg Id1 Kdr Id4 Id3 Hes1 Nfkb1 Tcf7l2 Rb1 Egf Psmd4 Igf1 Ngf Bmp6 Rela Pax2 Smad1 Rbl2 Bmp2 Rbl1 Smad4 Pax8 Tert HOMOLOGOUS RECOMBINATION%WIKIPATHWAYS_20260211%WP1296%RATTUS NORVEGICUS Homologous recombination Pold2 Rad51 Rad50 Pold1 Brca2 Rad52 Pold4 Pold3 Fsbp Nbn NOTCH SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP517%RATTUS NORVEGICUS Notch signaling pathway Aph1a Ncstn Ncor2 Dtx2 Dtx3 Dtx4 Dll3 Dll4 Rbpjl Maml1 Ctbp1 Ctbp2 Dtx3l Hdac1 Mfng Dvl1 Dvl2 Numb Dvl3 Hes5 Jag2 Jag1 Kat2a Rfng Crebbp Notch4 Numbl Notch1 Notch2 Lfng Hes1 Notch3 Psen1 Psen2 MITOCHONDRIAL GENE EXPRESSION%WIKIPATHWAYS_20260211%WP1301%RATTUS NORVEGICUS Mitochondrial gene expression Tfb1m Tfb2m Camk4 Prkar1b Ppp3ca Mterf1 Ppargc1a Nrf1 Ppargc1b Gabpa Myef2 Esrra Gabpb2 Tfam Pprc1 Polrmt AMINO ACID CONJUGATION OF BENZOIC ACID%WIKIPATHWAYS_20260211%WP1287%RATTUS NORVEGICUS Amino acid conjugation of benzoic acid Acss2 Glyat IRINOTECAN PATHWAY%WIKIPATHWAYS_20260211%WP124%RATTUS NORVEGICUS Irinotecan pathway Bche Abcc1 Abcc2 Ces1f Ces1e Ces1d Ces2c Abcg2 VEGFR 3 SIGNALING%WIKIPATHWAYS_20260211%WP1964%RATTUS NORVEGICUS VEGFR 3 signaling Casp9 Bad Nos3 Shc1 Itpkc Flt4 Mapk1 Plcg1 Mapk3 Akt1 Pik3cg Grb2 Vegfd Vegfc ATM SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP654%RATTUS NORVEGICUS ATM signaling pathway Cdk6 Brca1 Pmaip1 Bax Ccne1 E2f1 Cdk1 Bak1 Cdkn1a Tp53 Rprm Casp9 Rb1 Sfnl1 Ccnb1 Casp3 Ccnd1 Cycs Chek2 Gadd45a Necab3 ESTROGEN SIGNALING%WIKIPATHWAYS_20260211%WP1279%RATTUS NORVEGICUS Estrogen signaling Taf9 Polr2g Polr2h Polr2f Polr2i Polr2j Gtf2h2 Gtf2h1 Gtf2h4 Gtf2h3 Gngt1 Jun Mapk14 Ercc2 Ercc3 Gper1 Esr1 Cdk7 Map2k1 Gnb1 Taf7 Taf6 Chuk Taf5 Hras Hdac1 Crebbp Mapk1 Akt1 Grb2 Ccnd1 Fos Brca1 Elk1 Mapk9 Ikbkb Ilk Braf Mnat1 Hdac3 Nfkb1 Hdac2 Hdac5 Taf13 Taf12 Gtf2f2 Tbp Ccnh Prkaca Gtf2b Gtf2e1 Sos1 Shc2 Polr2c Src Polr2a Polr2b WNT SIGNALING PATHWAY AND PLURIPOTENCY%WIKIPATHWAYS_20260211%WP1288%RATTUS NORVEGICUS Wnt signaling pathway and pluripotency Jun Ctnnb1 Pafah1b1 Ctbp1 Map3k7 Ctbp2 Ppp2r3a Rhoa Sox2 Ppp2r2c Dvl1 Ppp2r2b Dvl2 Wnt5a Wnt5b Dvl3 Wnt9b Ppp2cb Ppp2ca Ppard Prkcq Gsk3b Crebbp Prkci Ptpa Prkcd Prkce Axin1 Axin2 Prkca Wnt16 Fbxw2 Lef1 Wnt11 Tcf7 Lrp6 Nlk Nkd2 Lrp5 Wnt6 Wnt3a Tmem97 Wnt7a Wnt2 Tcf7l1 Prkcz Wnt4 Cd44 Wnt3 Pou5f1 Fosl1 Fzd3 Ccnd2 Fzd2 Fzd4 Fzd9 Fzd8 Nanog Ppp2r2a Wnt2b Ppp2r1a Apc Plau Ctnnd1 Ppm1j Mapk10 Prkcb Ccnd1 Tp53 Mapk9 RELATIONSHIP BETWEEN GLUTATHIONE AND NADPH%WIKIPATHWAYS_20260211%WP2562%RATTUS NORVEGICUS Relationship between glutathione and NADPH Dffb Abcc1 Txn1 Gpi Mapk8 Alox5 Eno1 Map3k5 Ftl1 Casp3 Nnt Fth1 Pgam2 Pgm2 Ugdh Pgm1 Ptgr1 G6pd Kif1b Bax Gapdh Pgd Tfr2 Gstp1 Cdkn1a Tp53 Tkt Gapdhl6 Pklr Rpe Taldo1 Dpep2 Aldoa Rpia Pfkl Pgk1 Ugp2 Gclm Ugt8 Ltc4s Nqo1 Gsn Tfrc Gss Gsr Anpep Gck Fas Pgls Dffa TNF ALPHA AND MUCUS PRODUCTION IN LUNG EPYTHELIUM%WIKIPATHWAYS_20260211%WP1487%RATTUS NORVEGICUS TNF alpha and mucus production in lung epythelium Tgfa Ikbkg Tnf Nfkbia Egfr Il6 Tnfrsf1a Muc2 Ripk2 Tradd Ikbkb Rps6ka2 Traf2 Shc1 Raf1 Tlr4 Nfkb1 Mapk1 Map2k1 Grb2 Chuk Rela Sos1 WNT SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP375%RATTUS NORVEGICUS Wnt signaling pathway Jun Raf1 Csnk2a2 Csnk2a1 Mark2 Cdh1 Sox9 Tax1bp3 Rac1 Skp1 Sfrp2 Csnk2b Ctnnb1 Sfrp1 Ctbp1 Dkk1 Map3k7 Ctbp2 Prkcg Magi3 Rhoa Ror2 Crybb2 Csnk1d Dvl1 Btrc Dvl2 Wnt5a Sall1 Cdc25c Dvl3 Senp2 Ruvbl1 Ppp2ca Vangl2 Csnk1a1 Dab2 Gsk3b Camk2g Camk2d Tfap2a Camk2b Camk2a Axin1 Arrb2 Axin2 Arrb1 Prkca Brd7 Jup Map1b Lef1 Ctnnbip1 Ankrd6 Bcl9 Lrp6 Dlg1 Nlk Dlg2 Mapk8ip1 Lrp5 Dlg4 Cul1 Wnt3a Tcf4 Tmem97 Nr5a1 Wnt7a Hipk2 Wnt2 Wnt4 Wnt3 Fzd2 Fzd4 Fzd9 Fzd8 Apc Mapk1 Mapk3 Akt1 Mapk8 Prkcb Ccnd1 Cdk1 Mapk9 Tbp Pax2 Smad4 STATIN PATHWAY%WIKIPATHWAYS_20260211%WP145%RATTUS NORVEGICUS Statin pathway Mttp Soat1 Hmgcr Lpl Apoe Cyp7a1 Lcat Abca1 Scarb1 Apoc1 INTERACTIONS BETWEEN CFTR AND OTHER ION CHANNELS%WIKIPATHWAYS_20260211%WP1485%RATTUS NORVEGICUS Interactions between CFTR and other ion channels Cftr Nherf1 Scnn1b Scnn1g COMPLEMENT AND COAGULATION CASCADES%WIKIPATHWAYS_20260211%WP547%RATTUS NORVEGICUS Complement and coagulation cascades Cr2 Serping1 Cr1l Kng2l1 C3ar1 Serpinf2 Plau Mbl1 Fgb Vwf Masp1 Masp2 Tfpi C8b F2 F3 C4a F7 F8 F9 Serpine1 Plaur Cfb C1qb Cfd C1qa Cd59b Cfh Cfi F2r Plg Klkb1 Kng2 C2 Proc C6 C9 Serpind1 F13b Cd46 F10 C1s C1r F12 Plat Thbd Pros1 Serpinc1 A2m Cpb2 Cd55 C1qc TRANSLATION FACTORS%WIKIPATHWAYS_20260211%WP149%RATTUS NORVEGICUS Translation factors Eif3j Pycr3 Eif2s3 Eif2ak1 Eef1g Eif4ebp2 Eif2ak2 Eif3f Eif4ebp1 Eif4g1 Eif2ak3 Eif4g3 Eif3b Eif3a Eif1a Eif5b Eif5a Eif2b3 Eif2b2 Eif2b5 Eif2b4 Kcnq2 Eif2s2 Eef2k Eif2b1 Eif4h Paip1 Eif4e Eif1 Eif1ax Eif6 Eif4a2 Eif4a1 Etf1 Gspt2 Cluh Eef1a2 Eef1d ACETATE MEDIATED PROMOTION OF METABOLIC SYNDROME%WIKIPATHWAYS_20260211%WP3650%RATTUS NORVEGICUS Acetate mediated promotion of metabolic syndrome Ins2 Gast OXIDATIVE PHOSPHORYLATION%WIKIPATHWAYS_20260211%WP1283%RATTUS NORVEGICUS Oxidative phosphorylation Mt-nd6 Atp5mc1 Mt-nd1 Ndufb6 Mt-nd3 Mt-nd4l Ndufb5 Mt-nd2 Ndufb8 Ndufb7 Atp5mc3 Atp5mf Atp5me Ndufv1 Ndufv3 Atp5f1a Ndufa10l1 Ndufab1 Ndufc1 Ndufc2 Ndufa2 Ndufa5 Gzmb Ndufa4 Atp5pb Gzmc Ndufa9 Ndufa8 Atp5pf Ndufb10 Atp5po Ndufs3 Ndufs2 Ndufs5 Ndufs4 Ndufs6 Mt-co3 Ndufs8 Mt-nd5 Adck2 Mt-nd4 Ndufb2 Mt-atp6 G13 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP520%RATTUS NORVEGICUS G13 signaling pathway Arhgef1 Arhgdib Map3k4 Mapk10 Rps6kb1 Iqgap1 Rac1 Pak3 Pik3cd Iqgap2 Cdc42 Ppp1cb Diaph1 Tnk2 Cfl2 Rhpn2 Wasl Sh3rf1 Cit Limk1 Cyfip1 Rock2 Rock1 Mybph Pkn1 Pik3r2 Pip4k2a VEGF RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260211%WP1965%RATTUS NORVEGICUS VEGF receptor signal transduction Prkci Sh2d2a Casp9 Mapkapk2 Bad Nos3 Pxn Shc1 Pgf Raf1 Hspbp1 Prkca Pik3r3 Mapk1 Vegfb Plcg1 Akt1 Grb2 Rac1 Vegfc Src PROXIMAL TUBULE TRANSPORTERS%WIKIPATHWAYS_20260211%WP3881%RATTUS NORVEGICUS Proximal tubule transporters Slc1a1 Atp6v0c Car7 Slc4a4 Slc38a7 Slc34a1 Slc6a19 Slc7a6 Nherf1 Slc7a7 Car2 Atp1b1 Slc9a3 Slc9a8 Slc13a3 Slc7a8 Atp6v1a Slc13a1 Slc34a2 Slc13a2 Slc7a9 Atp6v1b2 Atp6v0d2 Atp6v0d1 Atp6v1b1 Slc16a10 Atp6v1g1 Ca4 Slc22a8 Atp6v1d Ca14 Atp6v1h Slc20a2 Slc22a6 Car15 Slc26a1 Atp1a1 Fxyd4 Slc22a5 Tctn2 Atp6v0a2 Atp6v0a4 Atp6v1e1 Atp6v1g3 Atp6v0e2 Atp6v0a1 Nherf2 IL 3 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP319%RATTUS NORVEGICUS IL 3 signaling pathway Lck Mapk14 Raf1 Map2k1 Rac1 Hras Atf2 Mapk7 Socs3 Spi1 Ywhaq Birc5 Matk Ppp2ca Crkl Tnfrsf1b Bcl2l11 Gsk3b Csf2rb Kcnip3 Ywhab Rac2 Rara Slc2a1 Jak2 Prkca Jak1 Foxo1 Rap1a Fcer2 Syk Mmp2 Gab1 Bcl2l1 Rack1 Gab2 Mmp9 Dnm1 Hck Rxra Gsk3a Pik3r1 Crk Gata2 Vcl Chek1 Ptpn6 Il3ra Selp Il3 Pak1 Rps6kb2 Hspb1 Ptpn11 Bad Fyn Shc1 Lyn Pik3ca Bmx Mapk1 Ptk2 Stat5a Mapk3 Stat5b Akt1 Tec Fes Rapgef1 Grb2 Mapk8 Stat3 Pik3cd Prkcb Cdc42 Bax Pik3r2 Mapk9 Id1 Mapkapk2 Pxn Nfkb1 Prkaca Sos1 Src SULINDAC METABOLIC PATHWAY%WIKIPATHWAYS_20260211%WP2541%RATTUS NORVEGICUS Sulindac metabolic pathway Msra Cyp1a1 Msrb2 MISMATCH REPAIR%WIKIPATHWAYS_20260211%WP1295%RATTUS NORVEGICUS Mismatch repair Pold1 Lig1 Pcna Msh2 Rfc1 NUCLEAR RECEPTORS%WIKIPATHWAYS_20260211%WP217%RATTUS NORVEGICUS Nuclear receptors Esr1 Nr3c1 Nr2c2 Nr2e1 Hnf4a Nr1i3 Nr1i2 Esrrb Rarb Nr2f6 Ppard Thrb Nr1d2 Thra Nr2f2 Vdr Nr2f1 Rara Nr1h3 Rorc Nr1h2 Ppara Pparg Esr2 Rxrb Ror1 Rxrg Nr5a2 Nr4a2 Esrra Nr5a1 Rxra NON HOMOLOGOUS END JOINING%WIKIPATHWAYS_20260211%WP1277%RATTUS NORVEGICUS Non homologous end joining Xrcc6 Rad50 Prkdc Xrcc4 MONOAMINE GPCRS%WIKIPATHWAYS_20260211%WP276%RATTUS NORVEGICUS Monoamine GPCRs Hrh1 Chrm3 Htr6 Chrm2 Htr7 Chrm5 Chrm4 Hrh2 Drd1 Adrb1 Drd3 Drd4 Drd5 Adra1b Adrb3 Adra1d Htr1d Htr1f Htr5b Htr5a Adra1a Htr2a Htr2c Htr1a Adra2a Adra2c Adra2b Htr4 Chrm1 HYPERTROPHY MODEL%WIKIPATHWAYS_20260211%WP442%RATTUS NORVEGICUS Hypertrophy model Myog Atf3 Eif4ebp1 Jund Wdr1 Ankrd1 Hbegf Zeb1 Il1a Dusp14l1 Eif4e Ifng Ifrd1 Il1r1 Ccn1 Nr4a3 THICK ASCENDING LIMB TRANSPORTERS%WIKIPATHWAYS_20260211%WP3882%RATTUS NORVEGICUS Thick ascending limb transporters Slc4a7 Slc12a1 Slc9a2 Aqp1 Kcnk12 Kcnq1 Slc12a7 Kcnj16 Clcnkb Car2 Clcnka Atp1b1 Slc9a3 Atp1a1 Ca4 HYPOTHETICAL NETWORK FOR DRUG ADDICTION%WIKIPATHWAYS_20260211%WP1281%RATTUS NORVEGICUS Hypothetical network for drug addiction Drd1 Drd4 Mapk1 Mapk3 Map2k1 Grin2d Grin2a Grm1 Camk2b Grm5 Prkce Adcy1 Grin1 Adcy8 Acta1 Nisch Krit1 Camk4 Terf2ip Gria2 Gria1 Ppa1 Prkaca Grin2c Grin2b METAPATHWAY BIOTRANSFORMATION%WIKIPATHWAYS_20260211%WP1286%RATTUS NORVEGICUS Metapathway biotransformation Hs3st6 Cyp2s1 Cyp17a1 Cyp4f39 Baat Naa20 Akr1d1 Kcnab2 Kcnab3 Sult1e1 Cyp2r1 Fmo1 Fmo3 Fmo2 Fmo5 Hs6st3 Fmo4 Hs6st1 Akr1b10 Cyp26c1 Cyp21a1 Gal3st4 Gal3st3 Glyat Cyp7a1 Cyp1a1 Chst10 Akr7a3 Chst11 Chst12 Akr7a2 Cyp2u1 Chst13 Cyp4f18 Chst14 Cyp4f17 Gstk1 Comt Cyp1b1 Ndst1 Cyp4x1 Ndst3 Sult4a1 Cyp26a1 Cyp11b2 Sult1b1 Hs3st3b1 Gstm7 Gstm5 Gstm4 Gstm1 Cyp27b1 Cyp2f2 Gstcd Cyp8b1 Cyp51 Hs2st1 Sult1a1 Tpmt Hnmt Naa50 Cyp46a1 Nat8 Nat1 Cyp2e1 Nat2 Ephx1 Ephx2 Akr1a1 Nat9 Sult2b1 Inmt Sult6b2 Gstp1 Naa40 Ugt2b1 Gsto1 Mgst3 Nat10 Mgst1 Akr1b1 Cyp7b1 Gpx2 Hs3st3a1 Chst1 Sult2a1 Chst3 Sult2a6 Chst4 Chst6 Cyp24a1 Chst9 Gss Naa30 Gsr Akr1c1 Zfp628 Gstz1 Hs3st2 Hs3st5 METHYLATION%WIKIPATHWAYS_20260211%WP1282%RATTUS NORVEGICUS Methylation Comt Inmt Pnmt Mat2a Mat1a Hnmt IL 6 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP135%RATTUS NORVEGICUS IL 6 signaling pathway Il6 Eif4ebp1 Rps6ka2 Jun Mapk14 Raf1 Map2k1 Rac1 Hras Erbb2 Map3k7 Ppp2r3b Eif4e Ppp2r3a Hsp90aa1 Hdac1 Foxo4 Mapt Ppp2r2c Foxo3 Ppp2r2b Cd40 Socs3 Cdk5r1 Fgr Btk Ppp2cb Sgk1 Ppp2ca Il6st Ppp2r5c Cebpb Gsk3b Map2k6 Crebbp Ppp2r5b Ptpa Ppp2r5a Prkcd Ncoa1 Il6r Inppl1 Ptk2b Jak2 Eif2a Jak1 Map2k4 Foxo1 Cdk9 Map2k2 Ppp2r5e Cdk5 Hnf1a Gab1 Nlk Daxx Gab2 Tmem97 Hck Pik3r1 Hspb1 Casp9 Ptpn11 Bad Fyn Ppp2r2a Shc1 Lyn Ppp2r1a Bmx Mapk1 Ptk2 Plcg1 Stat5a Mapk3 Stat5b Map3k4 Akt1 Tec Rps6kb1 Fes Grb2 Mapk8 Stat3 Casp3 Fos Pik3r2 Mapkapk2 Pxn Nfkb1 Rb1 Sos1 HEXOSES METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260211%WP3916%RATTUS NORVEGICUS Hexoses metabolism in proximal tubules Pdhx Psme3 Slc5a10 Sord Eno3 Eno2 Khk Pc Mpc1 Mpc2 Pdk4 Slc2a2 Pdk3 Pgam1 Slc2a5 Pdk2 Pdk1 Tpi1 Pdhb Tkfc Ldha Ldhb Fbp1 Dld Aldob Aldoc Acly Pdha1 Slc5a1 Pck1 Gpi Slc5a2 Pfkp Slc5a9 Eno1 Got1 Mdh1 Mdh2 Got2 G6pc1 Pgam2 Hk1 Pdp1 Pdp2 Gapdh Pklr Akr1b1 Aldoa Pfkl Pgk1 NUCLEOTIDE GPCRS%WIKIPATHWAYS_20260211%WP502%RATTUS NORVEGICUS Nucleotide GPCRs Adora2b Adora2a P2ry6 Lpar6 Adora1 P2ry2 P2ry1 Lpar4 SELENIUM METABOLISM SELENOPROTEINS%WIKIPATHWAYS_20260211%WP1293%RATTUS NORVEGICUS Selenium metabolism selenoproteins Sephs1 Nfe2l2 Trnau1ap Jun Fos Selenbp1 Msrb1 Txnrd2 Rpl30 Eefsec Crem Sp3 Nfkb1 Selenof Sars2 Gpx2 Selenoi Sars1 Selenok Fabp1 Selenoo Selenop Gpx3 Rela Gpx6 Selenos Dio1 Selenot Dio2 Dio3 Selenov Selenow TRANSCRIPTIONAL ACTIVATION BY NFE2L2 IN RESPONSE TO PHYTOCHEMICALS%WIKIPATHWAYS_20260211%WP1280%RATTUS NORVEGICUS Transcriptional activation by Nfe2l2 in response to phytochemicals Nfe2l2 Aimp2 Gclm Maf Hmox1 Nqo1 Mapk8 Ephb2 Cebpb Prkca POLYOL PATHWAY%WIKIPATHWAYS_20260211%WP1303%RATTUS NORVEGICUS Polyol pathway Sord Khk Akr1b1 Aldob RETINOL METABOLISM%WIKIPATHWAYS_20260211%WP1297%RATTUS NORVEGICUS Retinol metabolism Lpl Dhrs3 Aldh1a1 Cd36l1 Rdh12 Cyp26a1 Aldh1a3 Rdh10 Adh5 Adh4 Adh1 Bco1 Npc1l1 Rpe65 Rbp7 Abcg8 Abcg5 Rbp4 Retsat Sult1a1 Crabp2 Cd36 Lrat Rlbp1 Cyp2e1 Sult2b1 Rarb Rara Rxrb Rxrg Rxra Scarb1 BETA OXIDATION OF UNSATURATED FATTY ACIDS%WIKIPATHWAYS_20260211%WP418%RATTUS NORVEGICUS Beta oxidation of unsaturated fatty acids Decr1 Hadha Hadhb Eci1 Acadm TNF ALPHA NF KB SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP457%RATTUS NORVEGICUS TNF alpha NF kB signaling pathway Map3k14 Ikbkg Tnf Nfkbia Tnfrsf1a Ripk2 Tradd Traf2 Csnk2a2 Csnk2a1 Mark2 Csnk2b Hdac1 Btrc Tnfrsf1b Crebbp Ywhab Gab1 Rack1 Cul1 Hspb1 Ptpn11 Ptk2 Akt1 Casp3 Nr2c2 Rpl30 Ikbkb Hdac2 Prkaca Src Chuk Nkiras1 Nkiras2 Tbkbp1 Map3k8 Rps11 Kcnq1 Ppp2ca Rpl6 Rps13 Pias3 Gsk3b Fbl Ube2i Akt2 Dpf2 Polr1b Rnf216 Polr1a Polr1g Fbxw11 Polr1e Casp8ap2 Txlna Tank Gtf2i Map3k3 Actl6a Map3k2 Map3k1 Smarce1 Tifa Ube2d2 Polr2sl1 Flna Prkcz Cdc34 Nfkbiz Glg1 Bag4 Ripk3 G3bp2 Dcaf7 Cops3 Nfkbib Cav1 Capn3 Kpna6 Ripk1 Mcc Kpna3 Kpna2 Dap Bcl3 Rel Tab2 Rps6kb1 Ccar2 Traf4 Mcm7 Pfdn2 Traf6 Faf1 Tnfrsf8 Ywhah Ikbke Ywhag Psmd12 Ywhae Smarcb1 Psmd13 Nfkb2 Alpl Rasal2 Akap8 Psmb5 Rpl8l1 Pkn1 Cyld Fkbp5 Mcm5 Fadd Tnip2 Tnip1 Psmc2 Nfkb1 Psmc3 Pdcd2 Nsmaf Zfand5 Commd1 Trpc4ap Psmd7 Casp7 Rela Psmd6 Fancd2 Psmd3 Elp1 Casp2 Ktn1 Pebp1 Lrpprc Mtif2 EPO RECEPTOR SIGNALING%WIKIPATHWAYS_20260211%WP1284%RATTUS NORVEGICUS EPO receptor signaling Socs1 Ptprc Epo Rasa1 Irs2 Ptpru Pdk1 Shc1 Raf1 Jak2 Mapk1 Stat5a Mapk3 Map2k2 Map2k1 Stat5b Akt1 Pik3cg Grb2 Stat3 Sos1 Src INFLAMMATORY RESPONSE PATHWAY%WIKIPATHWAYS_20260211%WP40%RATTUS NORVEGICUS Inflammatory response pathway Cd40 Lck Col1a2 Tnfrsf1b Tnfrsf1a Cd86 Col1a1 Cd40lg Il4r Cd80 Il2ra Il2rb Il2 Il4 Lama5 Vtn Il2rg Il5 Il5ra Lamc1 Lamb1 Thbs1 Ifng MYOMETRIAL RELAXATION AND CONTRACTION PATHWAYS%WIKIPATHWAYS_20260211%WP140%RATTUS NORVEGICUS Myometrial relaxation and contraction pathways Atf3 Il6 Prkd1 Ets2 Rgs4 Rgs5 Prkcg Rgs2 Gja1 Rgs3 Atf2 Rgs1 Crcp Slc8a1 Rgs9 Rgs6 Ywhaq Rgs7 Plcg2 Actb Myl4 Mylk2 Camk2g Prkch Camk2d Myl2 Rxfp2 Ywhab Camk2b Rxfp1 Camk2a Atf5 Arrb2 Maff Arrb1 Pkib Calca Grk5 Grk4 Atf6b Gnaq Prkar1b Pkia Grk6 Pkig Actg1 Oxtr Gabpa Gucy1a1 Dgkz Gnb2 Gnb4 Gnb3 Rln1 Gng12 Itpr3 Gng13 Itpr1 Ryr2 Plcb3 Atp2a3 Atp2a2 Oxt Adm Adcy3 Adcy4 Nos1 Nos3 Adcy2 Guca2b Adcy7 Guca2a Plcg1 Crhr1 Adcy5 Lpar1 Creb3 Adcy9 Cald1 Pde4b Prkacb Prkar1a Rgs20 Rgs17 Igfbp3 Gng3 Rgs19 Gng2 Igfbp4 Vkorc1l1 Rgs14 Gng7 Igfbp1 Rgs16 Pde4d Gng8 Actc1 Prkar2b Rgs10 Ackr5 Corin Ramp3 Il1b Gngt1 Jun Gnb1 Prkcq Prkcd Prkce Adcy1 Prkca Acta1 Prkcz Prkcb Ywhah Crh Ywhag Fos Ywhae Gsto1 Nfkb1 EBV LMP1 SIGNALING%WIKIPATHWAYS_20260211%WP1278%RATTUS NORVEGICUS EBV LMP1 signaling Map3k14 Nfkb2 Tradd Ikbkb Pdlim7 Nfkb1 Mapk1 Ifnb1 Ccl5 Mapk8 Chuk Rela Traf6 Map3k7 TRYPTOPHAN METABOLISM%WIKIPATHWAYS_20260211%WP270%RATTUS NORVEGICUS Tryptophan metabolism Aadat Cyp2d2 Ogdh Aanat Afmid Cyp1b1 Gcdh Aoc1 Dhcr24 Aldh1a1 Haao Asmt Echs1 Kynu Cat Mdm2 Cyp2a2 Cyp2a1 Ube3a Acmsd Ido1 Cyp2f2 Hadh Cyp1a1 Cyp2e1 Inmt Cyp7b1 Ddc Tph1 Aldh3a2 Aldh2 Aldh9a1 Acad10 Cyp2j3 Hsd17b10 Cyp2b15 Wars1 Cyp2j4 Prmt1 Tdo2 Cyp4f1 FATTY ACID BIOSYNTHESIS%WIKIPATHWAYS_20260211%WP504%RATTUS NORVEGICUS Fatty acid biosynthesis Decr1 Acss2 Acaca Echs1 Acly Hadh Mecr Echdc3 Echdc1 Echdc2 Acaa2 Acsl1 Scd Fasn Acsl5 Acsl6 Pc Acsl3 Acacb GPCRS CLASS B SECRETIN LIKE%WIKIPATHWAYS_20260211%WP378%RATTUS NORVEGICUS GPCRs class B secretin like Calcr Adgre5 Ghrhr Gipr Gcgr Adgre1 Adgrl2 Adgrl3 Sctr Adgrl4 Adcyap1r1 Adgrl1 Glp2r Vipr1 Calcrl Glp1r Crhr2 Crhr1 BRAIN DERIVED NEUROTROPHIC FACTOR%WIKIPATHWAYS_20260211%WP2148%RATTUS NORVEGICUS Brain derived neurotrophic factor Mapk1 Ngfr Map2k1 Ntrk2 Bdnf Plat Plg Raf1 Serpine1 TOLL LIKE RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP1309%RATTUS NORVEGICUS Toll like receptor signaling pathway Ikbkg Tnf Nfkbia Il6 Cd86 Cd80 Jun Mapk14 Tlr4 Map2k1 Rac1 Chuk Map3k7 Cd40 Map3k8 Map2k6 Akt2 Map2k4 Il12b Il12a Ticam2 Akt3 Lbp Ly96 Tlr1 Ifna4 Irf3 Ifna1 Pik3r5 Pik3r1 Irf7 Tlr8 Irf5 Tlr7 Tlr6 Tlr5 Tlr3 Tlr2 Cxcl11 Cxcl10 Map2k7 Ifnar1 Cxcl9 Ripk1 Ccl4 Ccl3 Pik3ca Spp1 Mapk1 Mapk13 Tollip Mapk3 Map2k3 Akt1 Tab2 Cd14 Mapk10 Pik3cg Mapk8 Pik3cd Traf6 Ikbke Fos Nfkb2 Pik3r2 Mapk9 Ikbkb Fadd Il1b Nfkb1 Pik3r3 Ifnb1 Ccl5 Rela TYPE II INTERFERON SIGNALING IFNG %WIKIPATHWAYS_20260211%WP1289%RATTUS NORVEGICUS Type II interferon signaling IFNG Socs1 Eif2ak2 Cxcl10 Ptpn11 Cxcl9 Ifngr2 Oas1a Ifngr1 Psmb9 Gbp1 Nos2 Tap1 Ifng Ciita Irf4 Reg1a Cybb Irf1 Irf2 Socs3 Irf8 Spi1 Isg15 Hist1h2ao Irf9 Ifit2 Prkcd Il1b Jak2 Ifnb1 Jak1 CFTR ACTIVITY IN THE PLASMA MEMBRANE%WIKIPATHWAYS_20260211%WP1488%RATTUS NORVEGICUS CFTR activity in the plasma membrane Ppp2ca Plcb3 Plcz1 Cftr Plcb2 Plcb1 Nherf1 Prkaa2 Snap23 Pdzk1 Ezr Prkaca Rack1 Prkcg Nherf2 GPCRS CLASS A RHODOPSIN LIKE%WIKIPATHWAYS_20260211%WP473%RATTUS NORVEGICUS GPCRs class A rhodopsin like Gpr174 Galr2 Gpr171 Galr3 Galr1 Cmklr1 Lhcgr Sstr5 Sstr4 Sstr3 Sstr2 Olr226 Sstr1 Avpr1b Mc5r Oprm1 Gpr75 Tbxa2r C5ar2 Or7c70 Ffar3 Fpr1 Aplnr Bdkrb2 Nmbr Fpr3 Ffar1 Bdkrb1 Fpr2 Ffar2 Ccr10 Ptgfr Or2b2 Or2j3 Hrh3 Agtr1a Or5v1b Gpr85 Or7a36 Opn4 Xcr1 Lpar5 Opn3 Olr1073 Gpr19 Sucnr1 Gpr18 Grpr Or6b1 Gpr15 Or2c1 Gpr17 Or13c7d Or5i1 Gpr12 Adora3 Or2t1 Oxtr Cckar Opn1sw Npbwr1 Nmur2 Prlhr Npy5r Ntsr2 Ntsr1 Brs3 Gpr25 Ptger4 Mc2r Gpr27 Ptger2 Gpr22 Ptger3 Gpr21 Fshr Ptger1 Ccr9 Mchr1 Ccr7 C3ar1 Ccr6 Ccr5 Ccr3 Ccr2 Mtnr1a Cckbr Agtr2 Npy4r Gpr37 Ptgir Gpr39 Or11a4 Rgr Or14j1 Or3a1e Mc4r Or10j27 Adora2b Ptafr Adora2a Npffr1 P2ry6 Or2f2 Lpar6 Npffr2 Adora1 Ptgdr2 P2ry2 Or2f1 P2ry1 Rho F2r Lpar4 Hcrtr1 Or5ap2b Or2w1 Gpr37l1 Cysltr2 Cysltr1 Npy2r Ackr4 Cnr1 Gpr4 Cnr2 Gpr3 Ackr2 Gpr6 P2ry10 Mc3r Or2ag1 P2ry13 P2ry12 P2ry14 Adra2a Mas1 Adra2c F2rl1 Adra2b Or10a4 Htr4 Gpr50 Chrm1 Oprk1 Hrh1 Or10a5 Chrm3 F2rl2 Htr6 F2rl3 Chrm2 Htr7 Chrm5 Chrm4 Hrh2 Drd1 Adrb1 Drd3 Drd4 Drd5 Adra1b Adrb3 Adra1d Gper1 Htr1d Htr1f Htr5a Adra1a Htr2a Htr2c Htr1a Hcar1 Ghsr Ednrb Gpr161 Ednra Cxcr1 Npy1r Rrh Ptgdr Or3a1 Oprd1 Or2h2 Gpr65 Or2h1 Gpr68 Cxcr4 Gpr63 Oprl1 Gpr173 NUCLEAR RECEPTORS IN LIPID METABOLISM AND TOXICITY%WIKIPATHWAYS_20260211%WP139%RATTUS NORVEGICUS Nuclear receptors in lipid metabolism and toxicity Abcb1a Abcd2 Abcc2 Abcd3 Cyp7a1 Cyp2c11 Abcb4 Cyp4b1 Cyp2b2 Abcg1 Cyp26a1 Abcc3 Abcb11 Cyp27b1 Cyp8b1 Abcg5 Cyp2e1 Nr1i3 Nr1i2 Rarb Ppard Vdr Rara Nr1h3 Ppara Pparg Cyp24a1 Abca1 SPINAL CORD INJURY%WIKIPATHWAYS_20260211%WP2433%RATTUS NORVEGICUS Spinal cord injury Il6 Btg2 Fkbp1a Tlr4 Il2 Ptprz1 Il4 Slit1 Slit2 Aqp4 Slit3 Sox9 Pdyn Rhoc Rgma Vcan Sema6a Lilrb2 Il1a Tnfsf13b Ifng Zfp36 Gap43 Gja1 Arg1 Il1r1 Prpg2 Omg Plxna2 Epha4 Mag Rtn4r Tacr1 Anxa1 Pla2g2a Ccng1 Ntn1 Klk8 Rtn4 Gfap Bcan Tnfsf13 C5 Grin1 Prkca Tgfb1 Gdnf Ccl2 Ngfr Pla2g5 Mbp Bdnf Cd47 Cxcl1 Cxcl2 Pla2g6 Fcgr2a Egr1 Mmp9 Ptpra Chst11 Ncan Col4a1 Acan Xylt1 Nox4 Vim E2f5 Selp Cxcl10 Nos1 Mapk1 Mapk3 Ppp3ca Nos2 Casp3 Ccnd1 Fos Gadd45a Necab3 E2f1 Rock2 Cdk1 Tp53 Il1b Rb1 KIT RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP147%RATTUS NORVEGICUS Kit receptor signaling pathway Socs1 Rasa1 Ptpru Raf1 Map2k1 Hras Fgr Btk Matk Crkl Csf2rb Jak2 Prkca Hck Pik3r1 Crk Stap1 Mitf Grb10 Ptpn6 Socs5 Socs4 Socs6 Cltc Sh3kbp1 Cblb Vav2 Ptpn11 Bad Dok1 Fyn Rps6ka1 Shc1 Lyn Kit Tnfrsf10b Mapk1 Spred1 Plcg1 Mpdz Stat5a Spred2 Stat5b Akt1 Grb7 Tec Abl1 Pik3cg Fes Grap Grb2 Plce1 Stat3 Sh2b2 Prkcb Pik3r2 Sos1 Src HEPATOCYTE GROWTH FACTOR RECEPTOR SIGNALING%WIKIPATHWAYS_20260211%WP94%RATTUS NORVEGICUS Hepatocyte growth factor receptor signaling Crk Rasa1 Pak1 Ptpn11 Jun Raf1 Pik3ca Mapk1 Ptk2 Mapk3 Map2k1 Rapgef1 Grb2 Mapk8 Stat3 Dock1 Hras Itga1 Rap1b Hgf Pten Map4k1 Fos Itgb1 Met Elk1 Crkl Pxn Ptk2b Rap1a Map2k2 Gab1 Sos1 Src PROTEASOME DEGRADATION%WIKIPATHWAYS_20260211%WP302%RATTUS NORVEGICUS Proteasome degradation Psmb9 Psmd12 Psmc6 Psmc5 Psmd13 Psma5 Rpn2 Psma2 Psmc4 Rpn1 Psmb5 Psme2 Psme1 Psmd11 Ube2b Uchl3 Psmb8 Psmb6l1 Psmc2 Psmb4 Psmc3 Psmb7 Psmd8 Uchl1 Psmb1 Psmd2 Psmd4 Psmd5 Psmd7 Psmb2 Ube2d3 Psmd6 Ube2d1 Psma7 Psmd3 TCA CYCLE%WIKIPATHWAYS_20260211%WP347%RATTUS NORVEGICUS TCA cycle Suclg2 Pdk4 Ogdh Pdk3 Pdk2 Pdhb Dld Pdha1 Fh Mdh1 Mdh2 Sdhc Sdhb Sdha Idh3b Afdn Pc Suclg1 NOD LIKE RECEPTOR NLR SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP1294%RATTUS NORVEGICUS Nod like receptor NLR signaling pathway Cd40 Ikbkg Mapk8 Chuk Ephb2 Rela Ikbkb Map3k7 OSTEOCLAST%WIKIPATHWAYS_20260211%WP489%RATTUS NORVEGICUS Osteoclast Ifnb1 Trpv5 Itgb3 Zcchc2 Ctsk Tnfsf11 Slc9a1 Atp6v1e1 Ifnar1 Spp1 HEDGEHOG SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP574%RATTUS NORVEGICUS Hedgehog signaling pathway Cdk1 Hhip Igf2 Crebbp Gli1 Gli3 Gli2 Ski Ptch2 Smo Ptch1 Sufu Sap18 Dyrk1a Ccnb1 P53 PATHWAY%WIKIPATHWAYS_20260211%WP655%RATTUS NORVEGICUS p53 pathway Chek1 Casp9 Sesn1 Zmat3 Serpinb5 Cdkn2a Bid Shisa5 Sfnl1 Tp73 Ccnb1 Adgrb1 Casp3 Cd82 Igfbp3 Cycs Tsc2 Pten Chek2 Perp Gadd45a Serpine1 Mdm4 Ppm1d Cdk6 Rchy1 Pmaip1 Bax Ccne1 Cdk1 Ccng1 Cdkn1a Tp53 Rprm Fas G1 TO S CELL CYCLE CONTROL%WIKIPATHWAYS_20260211%WP348%RATTUS NORVEGICUS G1 to S cell cycle control Mdm2 Cdk7 Ccna1 Ccne2 Cdkn2b Tfdp1 Cdkn2c Cldn5 Myt1 Mcm4 Mcm6 Mcm2 Pole2 Pola2 Ccng2 Creb3l4 Creb3l1 Orc5 Rpa3l1 Orc4 Orc6 Atf6b Orc1 Orc3 Rpa2 Wee1 E2f2 E2f3 E2f4 Cdkn1b E2f6 Pole Cdkn1c E2f5 Creb3 Mcm7 Ccnb1 Pcna Ccnd1 Gadd45a Necab3 Cdk6 Ccne1 E2f1 Cdk1 Cdkn1a Tp53 Mcm5 Mnat1 Rb1 Ccnh Rbl1 STEROID BIOSYNTHESIS%WIKIPATHWAYS_20260211%WP66%RATTUS NORVEGICUS Steroid biosynthesis Hsd3b5 F13b Hsd3b2 Hsd17b3 Cyp17a1 Hsd3b1 Hsd17b4 Hsd17b1 Hsd17b2 Hsd17b7 ANGIOTENSIN II SIGNALING ACUTE IN THICK ASCENDING LIMBS%WIKIPATHWAYS_20260211%WP3887%RATTUS NORVEGICUS Angiotensin II signaling acute in thick ascending limbs Itpr3 Itpr1 Calm2 Pdpk1 Pde2a Agtr1b Itpr2 Nos3 Agtrap Plcg1 Akt1 Agtr2 Prkcg Pten Agtr1a Plcg2 Akt2 Arrb2 Prkca Gnaq Prkaca Akt3 Dnm1 Mas1 Nox4 REGULATION OF ACTIN CYTOSKELETON%WIKIPATHWAYS_20260211%WP351%RATTUS NORVEGICUS Regulation of actin cytoskeleton Egfr Slc9a1 Raf1 Rac1 Actb Actg1 Pik3r1 Gng12 Crk Vcl Pak1 Ins1 Fgf2 Pik3ca Fgf1 Mapk1 Fgf4 Ptk2 Fgf3 Mapk3 Mapk4 Fgf6 Fgf5 Pik3cg Fgf8 Fgf7 Fgf9 Cfl1 F2 Nras Pip4k2b Pfn1 Arhgef7 Arhgef6 Myh10 Nckap1 Pdgfrb Pdgfra Pdgfa Rras2 Pik3c2b Pik3c2a Ssh3 F2r Fgfr3 Pik3c2g Ssh2 Fgfr4 Ssh1 Fgfr1 Fgfr2 Braf Mylk Cyfip2 Arpc5 Fgf16 Fgf14 Fgf18 Fgf19 Fgf12 Fgf13 Pik3c3 Fgf10 Fgf11 Enah Sos1 Baiap2 Git1 Fgf20 Fgf23 Chrm1 Rras Rassf7 Chrm3 Sos2 Gna12 Chrm2 Gna13 Fgd1 Chrm5 Bcar1 Chrm4 Pak6 Csk Pak2 Pak5 Pak4 Tmsb4x Arhgap35 Wasf2 Wasf1 Mos Pip5k1b Pip5k1a Map2k1 Rhoa Ins2 Pik3r5 Apc Arhgef1 Cd14 Iqgap1 Pak3 Pik3cd Dock1 Itga1 Cdc42 Cfl2 Limk1 Rock1 Pik3r2 Pip4k2a Ezr Pxn Pik3r3 Egf Gsn PROSTAGLANDIN SYNTHESIS AND REGULATION%WIKIPATHWAYS_20260211%WP303%RATTUS NORVEGICUS Prostaglandin synthesis and regulation Ptger4 Ptger2 Ptger3 Ptger1 Anxa8 Anxa6 Pla2g4a Prl Ptgds Cyp11a1 S100a6 Ptgir Scgb1a1 Hsd11b1 Hsd11b2 Tbxas1 Edn1 Hpgd Ptgfr Ptgis Anxa5 Anxa4 Anxa3 S100a10 Ptgs1 Anxa1 Ptgs2 Ednrb Ednra Ptgdr BURN WOUND HEALING%WIKIPATHWAYS_20260211%WP5057%RATTUS NORVEGICUS Burn wound healing Epo Col1a1 Jun Ankrd1 Dll4 Casp3 Ptgis Adora2b Pdgfa Il10 Arfgap1 Ccn2 Tp53 Gpr176 Chp1 Syp Il1rl1 Glb1 Il1b Cdc25b Acta1 Syk Igf1 Mmp9 Col4a1 GPCRS OTHER%WIKIPATHWAYS_20260211%WP409%RATTUS NORVEGICUS GPCRs other Or10a5 Chrm3 Chrm2 Htr7 Sstr2 Drd3 Drd4 Smo Adra1d Htr1f C5ar2 Ptgfr Ghrhr Adgrl2 Adgrl3 Gpr176 Grm1 Rxfp1 Gpr18 Prokr2 Grpr Gpr162 Adgrg1 Gnrhr Grm8 Gpr17 Gpr61 Or1n1 Alg6 Gpr135 Taar3 Rxfp3 Taar2 Taar5 Gpr183 Or2a5 Hrh4 Gpr88 Ntsr1 S1pr1 Celsr2 Uts2r Ltb4r2 Lgr6 Or10a2 Fshr Ccr5 Ccr2 Cckbr Htr2a Or3a1e Adora2a Or2f1 F2r Cnr1 Ednra Cxcr1 P2ry13 MRNA PROCESSING%WIKIPATHWAYS_20260211%WP529%RATTUS NORVEGICUS mRNA processing Srsf1 Ptbp2 Srsf9 Srsf7 Srsf6 Srsf5 Srsf4 Srsf3 Srsf2 Srek1 Srsf10 Srrm1 Rbm17 Linc00176 U2af1 Nxf1 Sf3a1 Sf3a2 Sf3a3 U2af2 Ncbp2 Ncbp1 Cd2bp2 Rbmx Snrpd1 Tra2b Celf4 Celf2 Pabpn1 Celf1 Snrpd3 Sf3b2 Sf3b3 Sf3b4 Rbm39 Sfswap Sf3b5 Srp54 Hnrnph2 Ppm1g Hnrnph1 Dicer1 Ddx20 Rngtt Smc1a Prmt1 Prpf4 Phf5a Prpf6 Prpf3 Prpf40a Scamp3 Hnrnpa2b1 Supt5h Cdc40 Rnmt Snrnp70 Clp1 Snrpb2 Xrn2 Spop Prpf8 Prpf18 Snrnp40 Dhx8 Hnrnpr Dhx9 Hnrnpu Papola Snrpb Snrpa1 Snrpa Clk2 Clk3 Clk4 Mettl3 Prp4k Ptbp1 Fus Sugp1 Sugp2 Srpk1 Cpsf4 Lsm7 Cpsf1 Hnrnpd Cpsf2 Cpsf3 Ddx1 Snrpepl2 Hnrnpk Hnrnpm Hnrnpab Cstf1 Ybx1 Clasrp Nudt21 Tmed10 Sfpq Prmt2 Cstf2 Dhx16 Cstf3 Dhx15 BETA OXIDATION META PATHWAY%WIKIPATHWAYS_20260211%WP372%RATTUS NORVEGICUS Beta oxidation meta pathway Acss2 Lpl Gcdh Tpi1 Echs1 Dld Hadh Acsl1 Hadha Acsl5 Hadhb Acsl6 Acsl3 Acadm Pnpla2 Acadvl Acat1 Crat Cpt2 Acads Cpt1a Lipe Gpd2 Lipf Acsl4 MIR219 IN OLIGODENDROCYTE DIFFERENTIATION AND MYELINATION%WIKIPATHWAYS_20260211%WP2811%RATTUS NORVEGICUS mir219 in oligodendrocyte differentiation and myelination Pdgfra Hes5 Zbtb18 Foxj3 Elovl7 Neurod1 Sox6 ACETYLCHOLINE SYNTHESIS%WIKIPATHWAYS_20260211%WP360%RATTUS NORVEGICUS Acetylcholine synthesis Pemt Pdha1 Ache Pcyt1a Ahsg SYNTHESIS AND DEGRADATION OF KETONE BODIES%WIKIPATHWAYS_20260211%WP349%RATTUS NORVEGICUS Synthesis and degradation of ketone bodies Hmgcl Bdh1 Oxct1 Hmgcs2 IL 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP569%RATTUS NORVEGICUS IL 2 signaling pathway Lck Socs1 Irs2 Il2ra Eif3b Mapk14 Raf1 Il2 Il2rg Map2k1 Chuk Ets2 Eif4e Foxo3 Socs3 Crkl Ptk2b Jak2 Jak1 Syk Rack1 Gab2 Pik3r1 Prkcz Crk Ptpn6 Jak3 Stam2 Cd53 Itm2b Stam Mtor Ptpn11 Nmi Fyn Mknk1 Shc1 Lyn Pik3ca Mapk1 Stat5a Mapk3 Stat5b Akt1 Rps6kb1 Pik3cg Grb2 Mapk8 Stat3 Pik3cd Nr3c1 Plcb1 Pik3r2 Mapk9 Mapkapk2 Nfkb1 Ybx1 Rela Sos1 Tert LIPID DROPLET METABOLISM%WIKIPATHWAYS_20260211%WP3901%RATTUS NORVEGICUS Lipid droplet metabolism Soat1 Lpin3 Pnpla2 Aup1 Gpat2 Lipa Lpin1 Plin2 Bscl2 Dgat2 Agpat5 Gpd2 Dgat1 Agpat3 Fitm2 Acsl1 Agpat4 Agpat1 Agpat2 Acsl3 FATTY ACID OMEGA OXIDATION%WIKIPATHWAYS_20260211%WP133%RATTUS NORVEGICUS Fatty acid omega oxidation Aldh2 Acad10 Aldh1a1 Cyp1a1 Cyp4a2 Cyp3a2 Adh5 Adh4 Adh7 Adh1 Cyp2e1 Adh6 GLUTATHIONE METABOLISM%WIKIPATHWAYS_20260211%WP469%RATTUS NORVEGICUS Glutathione metabolism Ggt5 Gstm5l G6pd Gstm6 Gstm3 Gstm2 Gstt2 Gstt1 Ggt1 Oplah Gpx2 Gclm Gpx3 Gss Gsr Anpep GPCRS CLASS C METABOTROPIC GLUTAMATE PHEROMONE%WIKIPATHWAYS_20260211%WP42%RATTUS NORVEGICUS GPCRs class C metabotropic glutamate pheromone Gprc5b Gprc5a Casr Grm1 Gprc5d Grm5 Gprc5c Grm3 Grm2 Grm4 Grm7 Gabbr1 Grm6 Grm8 Gabbr2 ACE INHIBITOR PATHWAY%WIKIPATHWAYS_20260211%WP557%RATTUS NORVEGICUS ACE inhibitor pathway Ace Agtr2 Ren Bdkrb2 Agt Agtr1b Kng2 Nos3 Kng2l1 OXIDATIVE STRESS RESPONSE%WIKIPATHWAYS_20260211%WP173%RATTUS NORVEGICUS Oxidative stress response Hmox1 Gstt2 Txnrd2 Mapk14 Cat Mgst1 Nfkb1 Mapk10 Nqo1 Gpx3 Nfix Cyp1a1 Sod3 Gsr Sod2 Sod1 Txn2 Cyba Fos Junb Xdh AFLATOXIN B1 METABOLISM%WIKIPATHWAYS_20260211%WP1300%RATTUS NORVEGICUS Aflatoxin B1 metabolism Gstm1 Ephx1 Akr7a3 Akr7a2 GLUCOCORTICOID METABOLISM%WIKIPATHWAYS_20260211%WP305%RATTUS NORVEGICUS Glucocorticoid metabolism Akr1c14 Cyp17a1 Cyp21a1 Cyp11a1 Hsd11b1 Hsd11b2 S1P RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260211%WP1312%RATTUS NORVEGICUS S1P receptor signal transduction S1pr1 Smpd2 Mapk12 Asah1 Pik3c2b Sphk2 Plcb3 Sphk1 Gnai1 Plcb2 S1pr3 Plcb1 Gnai3 Akt2 Mapk1 Mapk3 Mapk4 Akt1 Akt3 NUCLEOTIDE METABOLISM%WIKIPATHWAYS_20260211%WP146%RATTUS NORVEGICUS Nucleotide metabolism Polg Adss2 Sat1 Srm Dhfr Pold1 Prps2 Polb Impdh1 Nme2 Mthfd2 Hprt1 IL 5 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP44%RATTUS NORVEGICUS IL 5 signaling pathway Socs1 Nfkbia Jun Mapk14 Raf1 Il5 Rap1gap Pla2g4a Il5ra Itgam Rac1 Pim1 Sox4 Sdcbp Hras Ctnnb1 Alox5ap Hcls1 Itgb2 Unc119 Atf2 Foxo3 Btk Crkl Gsk3b Prkcd Ptk2b Jak2 Jak1 Syk Cdkn1b Hck Gsk3a Pik3r1 Ptpn6 Ptpn11 Rps6ka1 Shc1 Lyn Mapk1 Stat5a Mapk3 Stat5b Akt1 Pik3cg Rapgef1 Grb2 Stat3 Alox5 Sh2b2 Prkcb Bax Elk1 Pik3r2 Mapk9 Nfkb1 Shc2 P38 MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP294%RATTUS NORVEGICUS p38 Mapk signaling pathway Tradd Hspb1 Traf2 Mapk14 Ripk1 Mknk1 Shc1 Pla2g4a Rac1 Grb2 Hras Map3k5 Cdc42 Map3k7 Max Map3k9 Atf2 Mef2d Tgfb2 Mapkapk5 Rps6ka5 Tgfbr1 Elk1 Map2k6 Mapkapk2 Map2k4 Daxx Map3k1 INSULIN INDUCED PI3K AKT AND MAPK IN HEPATOCYTES%WIKIPATHWAYS_20260211%WP4229%RATTUS NORVEGICUS Insulin induced PI3K Akt and MAPK in hepatocytes Grb10 Irs2 Eif4ebp1 Mtor Bad Ins1 Shc1 Rps6ka1 Raf1 Mapk1 Acly Mapk3 Akt1 Rps6kb1 Grb2 Eif4e Tsc2 Rptor Pfkfb2 Gys1 Gys2 Rheb Foxk1 Akt1s1 Rps6 Tsc1 Mlst8 Foxo1 Pik3c3 Sos1 Gsk3a ADIPOGENESIS%WIKIPATHWAYS_20260211%WP155%RATTUS NORVEGICUS Adipogenesis Socs1 Tnf Srebf1 Irs2 Il6 Ncor2 Celf1 Dvl1 Socs3 Il6st Cebpb Ncoa1 Rara Foxo1 Lipe Hnf1a Ppargc1a Rxra Gata2 Lpl Lpin3 Stat5a Lpin1 Stat5b Plin2 Bscl2 Pck1 Stat3 Agpat2 Serpine1 Nr3c1 Gadd45a Necab3 Cfd E2f1 Cdkn1a Nr2f1 Nr1h3 Ppara Pparg Rxrg Agt Scd Ptgis Mef2d Wnt5b Ins2 Ppard Nampt Nrip1 Tgfb1 Trib3 Ahr Lifr Prlr Foxc2 Twist1 Ebf1 Mif Retn Lmna Mbnl1 Frzb Cntfr Gata3 Gata4 Gh1 Hif1a Gtf3a Ndn Cisd1 Pck2 Egr2 Lif Bmp4 Bmp3 Wwtr1 Cyp26a1 Bmp1 Hmga1 Plin1 Adipoq Epas1 Slc2a4 Sfrp4 Klf15 Ncor1 Ucp1 Gadd45b Pnpla3 Cebpd Ncoa2 Zmpste24 Asip Osm Dlk1 Mixl1 Mef2a Mef2b Klf6 Mef2c Klf5 Lep Spock1 Gdf10 Id3 Rb1 Igf1 Rbl2 Bmp2 Rbl1 Fas PEPTIDE GPCRS%WIKIPATHWAYS_20260211%WP131%RATTUS NORVEGICUS Peptide GPCRs Galr2 Galr3 Galr1 Lhcgr Sstr5 Sstr4 Sstr3 Sstr2 Sstr1 Avpr1b Mc5r Oprm1 Fpr1 Bdkrb2 Nmbr Fpr3 Bdkrb1 Fpr2 Ccr10 Agtr1a Tacr1 Grpr Gnrhr Cckar Oxtr Npy5r Ntsr2 Ntsr1 Brs3 Mc2r Fshr Ccr7 C3ar1 Ccr6 Ccr5 Ccr3 Ccr2 Cckbr Agtr2 Npy4r Mc4r Cxcr6 Tacr3 Tacr2 Tshr Tac4 Npy2r Ghsr Ednrb Ednra Cxcr1 Npy1r Mc3r Oprd1 Cxcr4 Oprl1 Oprk1 GENETIC ALTERATIONS OF LUNG CANCER%WIKIPATHWAYS_20260211%WP1968%RATTUS NORVEGICUS Genetic alterations of lung cancer Tgfb2 Ccne1 E2f1 Egfr Cdkn1a Crebbp Tp53 Bmyc Dmp1 Rasl11b Smad2 Mdm2 Raf1 Pik3ca Tgfb1 Mapk1 Rb1 Map2k1 Akt1 Pik3cd Erbb2 Ccnd1 Smad4 Necab3 OSTEOBLAST SIGNALING%WIKIPATHWAYS_20260211%WP227%RATTUS NORVEGICUS Osteoblast signaling Pdgfrb Pdgfra Slc34a1 Tnfsf11 Col1a1 Bglap Fgf23 Pth WNT MYOFIBROBLASTIC ACTIVATION OF HEPATIC STELLATE CELLS%WIKIPATHWAYS_20260211%WP3649%RATTUS NORVEGICUS Wnt myofibroblastic activation of hepatic stellate cells Pparg Wnt3a PENTOSE PHOSPHATE PATHWAY%WIKIPATHWAYS_20260211%WP282%RATTUS NORVEGICUS Pentose phosphate pathway G6pd Kif1b Pgd Tkt Rpe Taldo1 Pgls Rpia FRUCTOSE METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260211%WP3894%RATTUS NORVEGICUS Fructose metabolism in proximal tubules Slc2a5 Tpi1 Tkfc Fbp1 Aldoa Akr1b1 Aldob Pfkl Naglt1 Gpi Pfkp Slc5a9 Psme3 Slc5a10 Sord G6pc1 Hk1 Khk FOLIC ACID NETWORK%WIKIPATHWAYS_20260211%WP1311%RATTUS NORVEGICUS Folic acid network Msrb1 Txnrd2 Cat Fads2 Mt-co1 Gpx1 Selenok Mtr Kmo Tbxt Ptgds Gpx3 Alox5 Cbs Gpx6 Pnpo Mt-co2 Gsr Mthfr Sod1 Selenow Ptgis Xdh STRIATED MUSCLE CONTRACTION%WIKIPATHWAYS_20260211%WP316%RATTUS NORVEGICUS Striated muscle contraction Tmod1 Vim Acta2 Tpm4 Tpm3 Tpm2 Neb Tnni3 Tnni2 Tnni1 Myh3 Actn2 Actn3 Mybpc3 Myh8 Actn4 Myl9 Myh6 Actc1 Myl2 Acta1 Actg1 Tnnt3 Tnnt2 Tnnt1 Tnnc2 Tnnc1 MATRIX METALLOPROTEINASES%WIKIPATHWAYS_20260211%WP278%RATTUS NORVEGICUS Matrix metalloproteinases Tnf Mmp11 Cep295nl Mmp23 Mmp24 Mmp14 Mmp2 Mmp15 Mmp16 Mmp28 Mmp17 Timp3 Mmp9 Timp2 Timp4 Bsg Tcf20 Mmp21 GLYCOGEN METABOLISM%WIKIPATHWAYS_20260211%WP160%RATTUS NORVEGICUS Glycogen metabolism Calm2 Ppp2r2a Ppp2r1a Ppp2r3a Ppp2r2c Gbe1 Ppp2r2b Pgm1 Phkb Phka1 Phka2 Gyg1 Ppp2cb Ppp2ca Pygb Gys1 Phkg1 Gys2 Phkg2 Agl Gsk3b Ppp2r5b Pygm Ppp2r5a Ptpa Ugp2 Gsk3a MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP358%RATTUS NORVEGICUS MAPK signaling pathway Map3k14 Ikbkg Rasa1 Egfr Tnfrsf1a Traf2 Raf1 Rac1 Prkcg Mapt Atf2 Crkl Map2k6 Cacng8 Cacna1g Cacna1h Cacna1e Arrb2 Cacng7 Arrb1 Cacna1f Cacna1c Map2k4 Cacna1d Cacna1a Rap1a Cacna1b Cacng1 Cacng4 Map3k6 Daxx Cacng5 Mapk8ip1 Cacng3 Cacna1s Map3k20 Lamtor3 Rasgrp3 Rasgrp4 Rasgrp1 Flnc Rasgrp2 Gng12 Crk Flnb Stmn1 Stk4 Map4k4 Map4k3 Tgfb3 Nf1 Ppp3cc Pak1 Ppp3cb Hspb1 Map4k2 Rasgrf2 Faslg Mknk1 Ppp5c Fgf2 Pla2g4b Fgf1 Pla2g4e Mapk1 Fgf4 Pla2g4d Fgf3 Nfatc1 Mapk3 Nfatc3 Fgf6 Akt1 Rps6ka3 Fgf5 Rps6ka4 Fgf8 Grb2 Cacna2d1 Fgf7 Cacna2d3 Fgf9 Cacna2d4 Prkacb Dusp16 Nras Ptpn7 Ptpn5 Casp3 Dusp3 Ntf4 Dusp2 Gadd45a Hspa1l Dusp4 Pdgfrb Ntf3 Dusp10 Pdgfa Dusp9 Rras2 Dusp8 Cacnb4 Cacnb1 Cacnb2 Fgfr3 Taok2 Tp53 Taok1 Taok3 Mapk9 Fgfr4 Ntrk1 Ikbkb Rapgef2 Fgfr1 Mapk8ip3 Fgfr2 Braf Il1r2 Il1b Map3k11 Map3k13 Fgf16 Fgf14 Fgf18 Fgf19 Fgf12 Fgf13 Prkaca Fgf10 Fgf11 Sos1 Fgf20 Rras Sos2 Gna12 Pak2 Jun Mapk14 Mos Map2k1 Jund Pla2g4a Chuk Hras Il1a Map3k7 Il1r1 Tgfb2 Mapkapk5 Tgfbr1 Map3k8 Akt2 Prkcd Cdc25b Prkca Tgfb1 Ntrk2 Bdnf Nlk Akt3 Map3k2 Map3k1 Tmem97 Flna Map2k7 Mapk13 Map3k4 Tab2 Cd14 Mapk10 Ppp3ca Mapk8 Traf6 Map3k5 Cdc42 Map4k1 Fos Mef2c Nfkb2 Elk1 Elk4 Mapkapk2 Nfkb1 Egf Ngf Rela Fas CATECHOLAMINE SYNTHESIS%WIKIPATHWAYS_20260211%WP513%RATTUS NORVEGICUS Catecholamine synthesis Th Pah Ddc Dbh Pnmt RENIN ANGIOTENSIN SYSTEM%WIKIPATHWAYS_20260211%WP376%RATTUS NORVEGICUS Renin angiotensin system Ikbkg Pak6 Pak2 Pak5 Pak4 Jun Raf1 Rac1 Atf2 Agtr1a Prkcq Ptk2b Jak2 Map2k4 Map3k1 Itpr3 Itpr1 Pak1 Map2k7 Itpr2 Shc1 Pik3ca Mapk1 Mapk13 Ptk2 Mapk3 Mapk10 Agtr2 Grb2 Mapk8 Pak3 Stat3 Ptgir Fos Elk1 Plcb1 Mapk9 Ikbkb Ctsg Cpa3 Mme Ace Ace2 Ren Prkaca Rela Enpep Agt Ctsa Nln Cma1 Lnpep Anpep Mas1 PHASE I BIOTRANSFORMATIONS NON P450%WIKIPATHWAYS_20260211%WP1291%RATTUS NORVEGICUS Phase I biotransformations non P450 Ces2j Lipa Esd Pon3 Ces5a Pon1 Pon2 INSULIN SIGNALING%WIKIPATHWAYS_20260211%WP439%RATTUS NORVEGICUS Insulin signaling Map3k14 Socs1 Igf1r Irs2 Rps6ka2 Raf1 Rac1 Tsc2 Foxo3 Gyg1 Sgk1 Map2k6 Prkch Rac2 Inppl1 Slc2a1 Map2k4 Foxo1 Map2k2 Lipe Map3k6 Gab1 Gsk3a Pik3r1 Crk Map4k4 Map4k3 Pdpk1 Rps6kb2 Map4k2 Mtor Ptpn11 Shc1 Mapk1 Mapk3 Mapk4 Akt1 Rps6ka3 Pik3cg Rps6ka4 Grb2 Rapgef1 Pik3c2a Pik3c2g Mapk9 Ikbkb Map3k11 Map3k13 Pik3c3 Sos1 Shc2 Sos2 Cyth3 Mapk12 Grb14 Stxbp1 Stxbp2 Stxbp3 Stxbp4 Prkaa1 Eif4ebp1 Kif5b Cblc Shc3 Jun Insr Mapk14 Flot2 Flot1 Map4k5 Rab4a Xbp1 Kif3a Map2k1 Tbc1d4 Ehd1 Ehd2 Snap25 Arf1 Rhoj Hras Ptprf Cap1 Map3k7 Rrad Eif4e Inpp4a Ppp1r3a Map3k9 Vamp2 Rps6ka6 Mink1 Sgk3 Rps6ka5 Sgk2 Myo1c Map3k8 Rptor Enpp1 Ptpn1 Gys1 Stx4 Prkcq Gys2 Arhgap33 Rheb Gsk3b Map3k10 Prkci Mapk11 Akt2 Prkcd Tsc1 Prkca Trib3 Map3k3 Map3k2 Egr1 Map3k1 Prkcz Grb10 Cblb Map2k7 Rps6ka1 Slc2a4 Mapk13 Map3k4 Mapk10 Rps6kb1 Mapk8 Pik3cd Sh2b2 Map3k5 Prkcb Pten Map4k1 Reg1a Fos Elk1 Pik3r2 Prkaa2 Snap23 Pfkl SMALL LIGAND GPCRS%WIKIPATHWAYS_20260211%WP161%RATTUS NORVEGICUS Small ligand GPCRs Ptafr S1pr1 Ptger4 Ptger2 S1pr3 Ptger3 Ptger1 Cnr1 Cnr2 Mtnr1a Lpar1 Ptgdr Ptgir Ptgfr BIOSYNTHESIS OF ALDOSTERONE AND CORTISOL%WIKIPATHWAYS_20260211%WP508%RATTUS NORVEGICUS Biosynthesis of aldosterone and cortisol Hsd3b2 Cyp17a1 Cyp21a1 Cyp11b2 NUCLEAR FACTOR ERYTHROID DERIVED 2 LIKE 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP2376%RATTUS NORVEGICUS Nuclear factor erythroid derived 2 like 2 signaling pathway Acta2 Fmo1 Raf1 Akr1b10 Prkcg Mapk7 Actb Crebbp Map2k6 Slc2a1 Actg1 Scarb1 Pik3r1 Abcc1 Ldhb Fyn Pik3ca Mapk1 Mapk3 Nras Gstm5l Brca1 Gstm6 Gstm3 Rras2 Gstm2 Pik3c2b Gstt2 Pik3c2a Gstt1 Cdkn1a Tp53 Pik3c2g Actc1 Mapk9 Pik3c3 Sod3 Sod2 Sod1 Rras Nfe2l2 Hmox1 Eif2ak3 Abcc3 Jun Mapk14 Map2k1 Hras Map3k7 Prkcq Gsk3b Prkci Prkd3 Ube2k Prkcd Herpud1 Prkce Sqstm1 Prdx1 Abcc4 Prkca Acta1 Vcp Pmf1 Mafg Ubb Slc1a4 Mafk Actg2 Bach1 Dhcr7 Slc35b1 Akr7a3 Map3k1 Dnajc5 Aldh3a1 Xpo1 Akr7a2 Gsto2 Mgst2 Prkcz Cbr1 Pik3r5 Cdc34 Pik3r6 Dnajb4 Nqo2 Gstk1 Usp14 Fosl1 Ran Map2k7 Gstm5 Gstm4 Gstm1 Txn1 Mapk8 Pik3cd Prkcb Ftl1 Fth1 Ugdh Psmc6 Ephx1 Psmc5 G6pd Akr1a1 Psmc4 Gstp1 Pik3r2 Gsto1 Mgst3 Taldo1 Mgst1 Psmc2 Aldoa Pik3r3 Psmc3 Gclm Nqo1 Gss Gsr INTEGRIN MEDIATED CELL ADHESION%WIKIPATHWAYS_20260211%WP74%RATTUS NORVEGICUS Integrin mediated cell adhesion Itgb3 Mapk12 Bcar1 Pak6 Pak2 Pak4 Shc3 Raf1 Map2k1 Itgam Rac1 Hras Itgb2 Mapk7 Mylk2 Map2k6 Akt2 Rac2 Rap1a Map2k2 Akt3 Crk Vcl Itgax Itgav Itgae Pdpk1 Itgal Pak1 Vav3 Cav1 Itgad Capn3 Itgb8 Vav2 Itgb6 Fyn Itga2b Shc1 Itgb4 Itgb5 Mapk1 Tln1 Ptk2 Vasp Mapk4 Itga8 Map2k3 Akt1 Itga6 Mapk10 Itga9 Itga3 Rapgef1 Grb2 Itga4 Pak3 Itga2 Dock1 Itga10 Itga1 Cdc42 Capn9 Rap1b Git2 Cav3 Arhgef7 Capn5 Cav2 Itgb1 Capn7 Capn6 Capn1 Capn2 Zyx Capns1 Rock2 Rock1 Rho Pik3r2 Ilk Pxn Braf Selenop Sos1 Src ETHANOL METABOLISM RESULTING IN PRODUCTION OF ROS BY CYP2E1%WIKIPATHWAYS_20260211%WP4268%RATTUS NORVEGICUS Ethanol metabolism resulting in production of ROS by CYP2E1 Nfe2l2 Mafg Map2k1 Mapk8 Prkcb Cyp2e1 ONE CARBON METABOLISM%WIKIPATHWAYS_20260211%WP1292%RATTUS NORVEGICUS One carbon metabolism Mthfd1l Ahcy Folh1 Mtrr Dnmt3b Ftcd Dhfr Ahcyl2 Bhmt Tcn2 Dnmt3a Mthfd2 Aldh1l1 Shmt1 Gart Mtr Mat1a Mthfr APOPTOSIS%WIKIPATHWAYS_20260211%WP1290%RATTUS NORVEGICUS Apoptosis Dffb Ikbkg Igf1r Nfkbia Tnfrsf1a Igf2 Tradd Jun Traf2 Chuk Bid Tp73 Birc5 Tnfrsf1b Bcl2l11 Map2k4 Map3k1 Irf3 Pik3r1 Irf7 Irf5 Nfkbib Casp9 Bad Ripk1 Faslg Tnfrsf10b Akt1 Mapk10 Casp3 Irf4 Irf1 Irf2 Pmaip1 Bax Bak1 Tp53 Ikbkb Fadd Nfkb1 Prf1 Hells Traf1 Bcl2l2 Xiap Bnip3l Casp7 Rela Lta Irf6 Diablol1 Tnfrsf25 Casp2 Tp63 Fas Dffa FOCAL ADHESION%WIKIPATHWAYS_20260211%WP188%RATTUS NORVEGICUS Focal adhesion Tnr Col5a1 Arhgap5 Igf1r Itgb3 Reln Lama2 Egfr Lama3 Lama4 Col1a2 Thbs2 Thbs4 Col1a1 Blk Srms Txk Pdgfc Raf1 Chad Pdgfb Tesk2 Lama5 Col4a2 Vtn Tnk1 Ptk6 Col4a6 Ibsp Pelo Rac1 Lamc1 Actn1 Lamb1 Thbs1 Col11a1 Col11a2 Lamb3 Erbb2 Col6a2 Lamc3 Styk1 Pip5k1c Mapk7 Fgr Actb Mylk2 Map2k6 Rac2 Rap1a Map2k2 Actg1 Hck Pik3r1 Crk Vcl Pdpk1 Pak1 Bad Fyn Shc1 Pik3ca Mapk1 Ptk2 Mapk4 Akt1 Vwf Pik3cg Grb2 Rapgef1 Vegfd Vegfc Ccnd1 Pdgfrb Pdgfra Pdgfa Mapk9 Ilk Braf Mylk Selenop Sos1 Src Mapk12 Bcar1 Pak6 Pak2 Pak5 Pak4 Shc3 Jun Mapk14 Map2k1 Itgam Hras Itgb2 Gsk3b Akt2 Akt3 Col4a1 Pik3r5 Itgax Ccnd2 Itgav Itgae Itgal Cav1 Itgad Itgb8 Itgb6 Itga2b Itgb5 Spp1 Tln1 Vasp Itga8 Map2k3 Itga6 Itga9 Itga3 Mapk8 Itga4 Pak3 Pik3cd Itga10 Dock1 Cdc42 Rap1b Hgf Cav3 Diaph1 Tnk2 Pten Cav2 Itgb1 Met Capn1 Zyx Flt1 Rock2 Rock1 Elk1 Pik3r2 Kdr Pxn Pgf Vegfb Egf Igf1 Tnc Comp Ppp1r12a Tnn APOPTOSIS MODULATION BY HSP70%WIKIPATHWAYS_20260211%WP487%RATTUS NORVEGICUS Apoptosis modulation by HSP70 Hspa1b Tnfrsf1a Casp9 Fadd Ripk1 Faslg Nfkb1 Mapk10 Casp7 Bid Casp3 Map3k1 Casp2 Cycs Fas Casp6 Aifm1 G PROTEIN SIGNALING PATHWAYS%WIKIPATHWAYS_20260211%WP73%RATTUS NORVEGICUS G protein signaling pathways Gna12 Gna13 Gnai1 Slc9a1 Gnai3 Gngt1 Gnb1 Hras Prkcg Rhoa Pde7b Pde7a Akap7 Akap3 Akap4 Akap1 Gnaz Prkcq Akap10 Akap11 Prkci Prkd3 Akap12 Akap9 Prkcd Akap13 Prkce Adcy1 Pde8a Pde8b Adcy8 Kcnj3 Prkca Pakap Gna14 Gnao1 Gnal Prkar1b Gng5 Gnaq Pde4c Gnas Pde1c Pde1a Gng11 Gnb2 Gnb3 Prkcz Gng12 Gng13 Itpr1 Plcb3 Ppp3cc Adcy3 Adcy4 Adcy2 Adcy7 Arhgef1 Adcy5 Adcy9 Ppp3ca Pde4b Prkacb Nras Prkcb Prkar1a Gng3 Akap8 Pde4d Gng8 Prkar2b Prkaca Rras ESTROGEN METABOLISM%WIKIPATHWAYS_20260211%WP1302%RATTUS NORVEGICUS Estrogen metabolism Gstm1 Comt Cyp1b1 Nqo1 Sult1a1 Cyp1a1 Sult1e1 Arsl INTRACELLULAR TRAFFICKING OF CFTR%WIKIPATHWAYS_20260211%WP1486%RATTUS NORVEGICUS Intracellular trafficking of CFTR Cftr Nherf1 Fblim1 Ezr Rab7a Rab11a GLUCOCORTICOID EFFECT ON TARGET GENE EXPRESSION%WIKIPATHWAYS_20260211%WP1963%RATTUS NORVEGICUS Glucocorticoid effect on target gene expression Fkbp4 Pla2g4a Nfkbia Anxa1 Mt-co2 Tsc22d3 Nr3c1 Hspa4 Rras Nfkb1 ERBB SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP1299%RATTUS NORVEGICUS ErbB signaling pathway Crk Ereg Tgfa Nrg2 Nrg1 Areg Egfr Btc Nrg4 Nrg3 Eif4ebp1 Map2k7 Mtor Pak4 Cblc Jun Bad Mapk1 Ptk2 Plcg1 Stat5a Map2k1 Rps6kb1 Abl1 Grb2 Mapk8 Hbegf Hras Erbb2 Elk1 Cdkn1a Gsk3b Camk2a Prkca Egf Gab1 Akt3 Sos1 Shc2 Cdkn1b Src Pik3r5 GLUCURONIDATION%WIKIPATHWAYS_20260211%WP1276%RATTUS NORVEGICUS Glucuronidation Pgm1 Ugp2 Ugt2b7 Ugt2b1 Pgm5 Ugt2b35 Ugt2b34 Ugt2a1 Hk1 Pgm2 Ugdh CARDIOVASCULAR SIGNALING%WIKIPATHWAYS_20260211%WP590%RATTUS NORVEGICUS Cardiovascular signaling Col5a1 Stmn1 Thbs2 Col1a1 Hspb1 Vav2 Wnt2b Wasf1 Col4a2 Akt1 Vwf Mapk8 Vegfd Col11a1 Cfl1 Erbb2 Casp3 Arhgef7 Casp6 Capn6 Hspa1b Pdgfra Rras2 Map2k6 Pgf Egf Selenop Casp2 Tnc Col4a1 Wnt2 SELENIUM MICRONUTRIENT NETWORK %WIKIPATHWAYS_20260211%WP1310%RATTUS NORVEGICUS Selenium micronutrient network Cat Fads1 Fads2 Mt-co1 Gpx1 Selenok Mtr Kmo Selenop Tbxt Ptgds Gpx3 Alox5 Gpx6 Pnpo Mt-co2 Gsr Mthfr Sod1 Tbxas1 Ptgis Xdh IL 9 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP8%RATTUS NORVEGICUS IL 9 signaling pathway Socs3 Irs2 Jak3 Ptpn11 Shc1 Kat5 Il9 Vcp Mapk1 Jak1 Il9r Stat5a Mapk3 Il2rg Map2k1 Stat5b Akt1 Grb2 Stat3 Pik3r1 CHOLESTEROL METABOLISM%WIKIPATHWAYS_20260211%WP632%RATTUS NORVEGICUS Cholesterol metabolism Soat1 Hmgcr Lpl Srebf1 Apoe Fdps Idi1 Mvk Rusc1 Apoc2 Fdft1 Lss Dhcr7 Hmgcs1 Mvd Msmo1 Scarb1 Apoc1 IL 1 SIGNALING PATHWAY%WIKIPATHWAYS_20260211%WP355%RATTUS NORVEGICUS IL 1 signaling pathway Map3k14 Nfkbia Nfkbib Ptpn11 Mapk1 Tollip Plcg1 Mapk3 Map2k1 Akt1 Mapk8 Chuk Traf6 Il1a Il1rap Map3k7 Peli1 Irak4 Il1r1 Irak3 Irak2 Capn1 Sirpa Tab1 Il1rn Capns1 Sqstm1 Il1r2 Il1b Nfkb1 Rela Elp1 Prkcz P53 SIGNAL PATHWAY%WIKIPATHWAYS_20260211%WP656%RATTUS NORVEGICUS p53 signal pathway Pmaip1 Ccnb3 Bax Gadd45g Ccne1 Gtse1 Cdk1 Bbc3 Parp1 Tp53 Rprm Casp9 Mdm2 Igf1 Bid Casp3 Igfbp3 Perp Fas