Irinotecan pathway%WikiPathways_20260211%WP124%Rattus norvegicus Irinotecan pathway 24565 312382 25303 171118 100125372 113902 29225 65036 Glucuronidation%WikiPathways_20260211%WP1276%Rattus norvegicus Glucuronidation 289827 679990 289632 25058 83472 24645 286954 289533 83808 286954 305264 63867 286989 Non homologous end joining%WikiPathways_20260211%WP1277%Rattus norvegicus Non homologous end joining 360748 25019 309995 64012 EBV LMP1 signaling%WikiPathways_20260211%WP1278%Rattus norvegicus EBV LMP1 signaling 309452 116554 309165 286908 246756 24481 84351 311245 309361 313121 81736 81780 360640 309361 116590 Estrogen signaling%WikiPathways_20260211%WP1279%Rattus norvegicus Estrogen signaling 84577 50658 308415 307485 310784 363067 116590 266713 58919 81673 292778 84578 291703 24890 170915 84351 498109 289561 25636 361365 682902 171150 24516 497672 24185 303918 373541 294236 361580 24400 306516 83805 293621 81674 288588 313845 114486 170851 81649 81736 314436 314612 297893 288533 117526 54244 171104 314322 83503 81504 170922 294693 294018 680149 117017 84580 288651 363633 84389 309361 Transcriptional activation by Nfe2l2 in response to phytochemicals%WikiPathways_20260211%WP1280%Rattus norvegicus Transcriptional activation by Nfe2l2 in response to phytochemicals 24680 116554 288480 24253 83619 24451 54267 313633 24314 29739 Hypothetical network for drug addiction%WikiPathways_20260211%WP1281%Rattus norvegicus Hypothetical network for drug addiction 25050 294504 24411 305509 25432 50592 307861 362317 24412 29241 29340 24418 24414 29437 50689 116590 306255 24410 24316 29627 170851 24409 24245 24408 25636 Methylation%WikiPathways_20260211%WP1282%Rattus norvegicus Methylation 25331 171347 24661 81676 368066 24267 Oxidative phosphorylation%WikiPathways_20260211%WP1283%Rattus norvegicus Oxidative phosphorylation 114630 681024 362588 29754 361385 362344 312258 26197 679739 689938 64539 293991 296658 293453 25488 297990 316632 362440 192241 171375 293130 26197 26204 499529 26200 681418 102553861 171528 171290 100361261 295923 26202 26199 291660 289218 293652 294964 140608 26193 94271 690441 26203 65262 293655 26201 26194 EPO receptor signaling%WikiPathways_20260211%WP1284%Rattus norvegicus EPO receptor signaling 24514 83805 298947 81504 24335 85385 116551 50689 170851 58960 24185 116590 252971 25126 24918 25125 24699 116680 24703 313845 29376 25676 Metapathway biotransformation%WikiPathways_20260211%WP1286%Rattus norvegicus Metapathway biotransformation 362035 171445 498489 116631 116632 116631 116632 310848 246248 295430 316325 290623 246767 363618 299566 500801 690050 293779 81676 29725 84493 295934 25279 84468 64305 362782 499689 29326 120093683 500892 24192 293451 100359484 25426 114846 308445 360268 24298 26760 308190 24902 24912 114700 312495 499422 78959 25256 362228 368066 81869 311257 314694 291770 498166 25428 681913 54246 294449 297029 499302 292155 81924 24296 116686 58953 364476 24294 64352 289533 29633 307092 310855 500257 25429 140568 25315 303669 83783 288108 361631 303218 292915 25458 65030 307859 24423 58981 246245 29738 361718 246247 154985 25086 691394 500359 684979 25146 307838 171341 286954 296972 64570 24426 24267 289197 192242 25427 304322 Amino acid conjugation of benzoic acid%WikiPathways_20260211%WP1287%Rattus norvegicus Amino acid conjugation of benzoic acid 293779 311569 Wnt signaling pathway and pluripotency%WikiPathways_20260211%WP1288%Rattus norvegicus Wnt signaling pathway and pluripotency 364754 24205 29382 303251 84353 303181 24516 84006 25619 116466 54244 24672 24673 363595 24680 161452 499593 25272 64512 500047 114487 303586 64566 117281 312451 25682 85420 311881 497961 303330 295341 25023 316526 83721 83572 140584 24842 58919 24882 60660 50658 294562 114850 81717 25522 312781 64558 303811 25445 29134 266608 117273 364952 308068 79257 414065 84027 84426 117104 117256 266715 311163 313121 140584 29340 363122 25406 282582 170538 362102 293649 64033 Type II interferon signaling IFNG %WikiPathways_20260211%WP1289%Rattus norvegicus Type II interferon signaling IFNG 25712 116465 360697 84598 24514 89829 252971 25622 305896 170538 24714 291100 366126 24481 24599 304266 295277 364723 24967 24811 192281 245920 85483 66021 24494 294091 54287 24508 246759 298693 292060 290749 Apoptosis%WikiPathways_20260211%WP1290%Rattus norvegicus Apoptosis 492821 58918 116502 24508 81736 246097 100360940 24185 64639 25493 306886 290749 81525 25008 364081 25402 50669 25625 25718 309165 309361 24887 156767 64625 500592 25272 687813 84351 296953 114214 292892 64314 362675 64026 24483 309295 311786 60434 25513 246756 64041 364420 24516 140923 84359 293624 291100 24842 287398 63879 25385 294071 266610 64547 116667 246334 Phase I biotransformations non P450%WikiPathways_20260211%WP1291%Rattus norvegicus Phase I biotransformations non P450 307660 290401 25055 312086 685645 296851 679817 84024 One carbon metabolism%WikiPathways_20260211%WP1292%Rattus norvegicus One carbon metabolism 25331 81508 24312 680308 361472 85309 81522 362657 89833 444985 312192 64392 290947 287379 288259 444984 29443 64365 Selenium metabolism selenoproteins%WikiPathways_20260211%WP1293%Rattus norvegicus Selenium metabolism selenoproteins 498398 81736 297437 103689947 140927 362624 362713 65241 83619 113922 29326 685059 24516 292759 308993 286900 365802 29475 29360 309165 25545 290549 50551 314322 25430 64317 25620 259233 291314 266975 500255 499113 315216 64640 100362027 367846 65162 24360 Nod like receptor NLR signaling pathway%WikiPathways_20260211%WP1294%Rattus norvegicus Nod like receptor NLR signaling pathway 309361 309295 309165 116554 313633 313121 84351 171369 Mismatch repair%WikiPathways_20260211%WP1295%Rattus norvegicus Mismatch repair 81513 59294 81709 89809 100360342 25737 287524 Homologous recombination%WikiPathways_20260211%WP1296%Rattus norvegicus Homologous recombination 293144 499870 360254 287524 85482 297561 361698 313063 102550523 59294 287524 289758 64012 Retinol metabolism%WikiPathways_20260211%WP1297%Rattus norvegicus Retinol metabolism 114106 362662 24188 24705 155192 314264 313689 312495 432367 266603 114628 24539 25086 89826 25073 292915 64047 361801 353252 246298 25271 100145871 29646 83783 154985 29184 499985 24172 83574 29563 293049 25703 24706 ErbB signaling pathway%WikiPathways_20260211%WP1299%Rattus norvegicus ErbB signaling pathway 314612 84027 690919 497931 29414 25738 64022 116554 112400 24329 24337 64639 29183 361388 314436 24827 313845 83805 81504 498596 59325 24918 114851 170851 24516 25433 25313 116636 54245 24680 83840 83571 25400 56718 293621 292699 292756 363855 116590 25614 311860 432361 Aflatoxin B1 metabolism%WikiPathways_20260211%WP1300%Rattus norvegicus Aflatoxin B1 metabolism 171445 26760 499422 24423 25315 Mitochondrial gene expression%WikiPathways_20260211%WP1301%Rattus norvegicus Mitochondrial gene expression 25521 83474 308140 289307 294007 85261 363735 299604 293701 312195 295263 83516 291567 679712 25050 24674 Estrogen metabolism%WikiPathways_20260211%WP1302%Rattus norvegicus Estrogen metabolism 24267 360268 83783 310326 24314 24296 24423 25426 Polyol pathway%WikiPathways_20260211%WP1303%Rattus norvegicus Polyol pathway 25659 24190 24192 24788 Toll like receptor signaling pathway%WikiPathways_20260211%WP1309%Rattus norvegicus Toll like receptor signaling pathway 448830 81736 25408 24516 305354 289337 25513 81736 81649 311245 25233 81780 361677 64546 298947 305353 25272 497931 309361 29414 308267 25493 84405 311245 24835 171369 24481 25353 25542 310553 245920 29260 317468 298205 363984 293624 287398 24494 684440 313121 114495 364867 292892 309361 24498 56822 50689 366508 29513 60350 24481 288264 116554 306886 29469 296953 116590 170851 266610 311245 690894 60664 116596 363875 310553 29741 363855 246759 364594 24185 303200 309165 116637 309295 309452 84351 314322 170911 305236 50658 Peptide GPCRs%WikiPathways_20260211%WP131%Rattus norvegicus Peptide GPCRs 24180 289615 24182 25245 81509 25264 24938 260319 60463 117027 117029 308163 287673 363682 100124593 60628 25449 25477 25360 50577 29234 29235 24326 50672 24889 25706 292409 690158 292413 84007 54258 29310 25635 25726 29358 66024 25340 366274 64636 24613 29335 25601 29256 81668 84022 24807 25007 24808 282829 25033 54305 171044 25555 25354 100909648 29462 25342 282839 29471 Selenium micronutrient network %WikiPathways_20260211%WP1310%Rattus norvegicus Selenium micronutrient network 292301 24404 25526 25290 26195 116686 64533 25527 24786 24886 362657 59113 83512 29360 259233 290549 497811 81522 84575 26198 24248 64317 Folic acid network%WikiPathways_20260211%WP1311%Rattus norvegicus Folic acid network 292301 25527 259233 24786 83512 24250 50551 24248 362657 59113 25526 290549 25545 64317 81522 25290 26195 685059 116686 497811 64533 24404 26198 S1P receptor signal transduction%WikiPathways_20260211%WP1312%Rattus norvegicus S1P receptor signal transduction 170897 308589 84431 83537 29733 306792 24654 85240 29322 50689 116590 54268 60352 25686 25643 24185 25233 29414 289021 Fatty acid omega oxidation%WikiPathways_20260211%WP133%Rattus norvegicus Fatty acid omega oxidation 25086 266682 310903 24172 24172 24306 100145871 29646 24188 171178 304500 29539 24296 IL 6 signaling pathway%WikiPathways_20260211%WP135%Rattus norvegicus IL 6 signaling pathway 299147 313121 497961 303330 25125 299331 367901 54244 24471 117281 25402 81736 361388 25126 64639 24253 84482 170538 293621 116671 25614 24499 84492 313929 114495 65038 140908 29477 29517 24673 24498 81504 170915 25622 170851 361597 84027 363122 50689 116590 24185 302415 83840 24337 84598 25513 81649 24703 691318 25734 24672 24514 117269 682033 84477 362102 79113 308106 294515 58918 309179 312754 117256 171369 297893 313845 502531 25205 24918 24516 140926 24817 25150 25738 363875 362110 367786 89829 85385 81515 360820 29741 58960 116554 287398 117104 50646 314322 24708 60660 116636 289014 117045 Nuclear receptors in lipid metabolism and toxicity%WikiPathways_20260211%WP139%Rattus norvegicus Nuclear receptors in lipid metabolism and toxicity 313210 25747 25303 25664 84385 83569 24705 81924 114628 85264 29277 154985 65035 24873 140668 361523 25428 24706 114700 24307 24891 25279 58852 170913 25086 84356 25682 25270 170913 Myometrial relaxation and contraction pathways%WikiPathways_20260211%WP140%Rattus norvegicus Myometrial relaxation and contraction pathways 685451 25522 64532 114207 25391 24679 24681 81636 29340 59077 60449 114117 24678 314322 59075 25342 117558 114120 84583 80850 54295 24516 64508 58979 293508 406169 29307 24241 305509 25388 24598 308118 81749 689560 289076 56011 24498 59076 114205 399684 295144 25576 171140 54296 688228 54289 25023 116744 56820 24246 85420 24600 25687 114846 81648 24680 81667 25342 360622 54290 81821 54294 29693 362477 81666 29753 25504 25725 29481 84420 282840 29337 24494 108352647 25026 360857 25679 85421 287876 100361457 245986 363866 294962 25521 59293 81822 289596 364738 170538 363735 25656 25262 24245 58959 25616 24627 304063 25389 54223 29480 114705 29715 64055 25387 24392 56010 25685 266709 24626 680149 114906 25577 298400 29275 24484 25738 366960 81647 302950 29437 24400 363925 54293 29322 25400 81736 497757 Statin pathway%WikiPathways_20260211%WP145%Rattus norvegicus Statin pathway 24530 25728 24539 25292 25073 310900 25675 296371 313210 25428 81782 Nucleotide metabolism%WikiPathways_20260211%WP146%Rattus norvegicus Nucleotide metabolism 24689 59294 362329 302642 83782 680308 29240 24465 85472 24312 84596 289276 Kit receptor signaling pathway%WikiPathways_20260211%WP147%Rattus norvegicus Kit receptor signaling pathway 84427 25513 29741 85385 171081 81504 307200 305828 500616 54241 54245 83805 114633 24514 363616 116680 305269 24680 25738 24918 25126 298947 114203 498416 24185 84492 81515 312477 116689 25622 81771 25094 116590 311860 79113 25734 25676 361597 287942 252971 296603 60450 64639 313845 170915 25150 25023 293621 24703 305539 296072 84357 171136 364420 367901 64030 170851 25125 29365 Interactions between CFTR and other ion channels%WikiPathways_20260211%WP1485%Rattus norvegicus Interactions between CFTR and other ion channels 24255 24767 59114 24768 Intracellular trafficking of CFTR%WikiPathways_20260211%WP1486%Rattus norvegicus Intracellular trafficking of CFTR 24255 54319 59114 29448 362650 81830 24255 59114 362650 81830 TNF alpha and mucus production in lung epythelium%WikiPathways_20260211%WP1487%Rattus norvegicus TNF alpha and mucus production in lung epythelium 362491 116590 170851 24827 81736 309165 117269 25625 24835 85385 246756 309361 24329 311786 84351 24703 81736 313845 24572 25493 29260 309295 81504 24498 CFTR activity in the plasma membrane%WikiPathways_20260211%WP1488%Rattus norvegicus CFTR activity in the plasma membrane 25636 497197 85240 24654 24681 24255 65144 29322 78975 64630 83427 24672 54319 116501 65144 59114 Translation factors%WikiPathways_20260211%WP149%Rattus norvegicus Translation factors 27137 307503 116636 171145 501582 287703 365684 317163 287436 288516 298573 303300 296302 288599 299027 117019 361845 305506 54287 64514 287986 308306 24799 170848 293725 691947 25435 84005 303831 117045 300035 300033 292148 192234 29702 287444 293427 302697 Adipogenesis%WikiPathways_20260211%WP155%Rattus norvegicus Adipogenesis 24482 25527 25682 289311 24391 25585 24918 25126 114587 24413 60584 24253 154985 312495 25271 24705 58852 24539 78968 246097 680111 85471 25159 25664 309957 498607 499497 81518 24152 24835 81683 59086 24617 25139 246074 85489 25608 246250 54249 246299 24708 81758 246253 298199 24179 114851 399489 311562 117062 25629 24498 25112 299626 25695 83470 29373 25667 25296 308690 84482 84410 171356 83516 313929 83724 25747 25125 252971 89829 313173 81680 25205 282635 289747 24860 282582 83721 24817 83574 295691 24506 297508 306759 246273 54254 81808 304157 24684 362972 362160 29560 58954 89803 54299 360801 85497 114090 116543 29452 25690 294362 295062 79216 361722 60374 311821 313564 313977 25330 362282 361042 29376 362261 Glycogen metabolism%WikiPathways_20260211%WP160%Rattus norvegicus Glycogen metabolism 24701 24673 361377 25623 309179 140671 64561 117256 25739 289827 690987 50686 363122 81675 117281 24244 24672 60660 362029 312754 50663 678739 117104 84027 29353 288333 24645 362102 Small ligand GPCRs%WikiPathways_20260211%WP161%Rattus norvegicus Small ligand GPCRs 114211 57302 25637 81752 84023 306792 29733 25248 58949 116744 292661 498475 24929 25652 Oxidative stress response%WikiPathways_20260211%WP173%Rattus norvegicus Oxidative stress response 171341 24787 81736 81524 25272 24451 81649 79129 50551 314322 24248 24296 24517 29487 25352 497811 64317 116686 79462 24314 24786 Focal adhesion%WikiPathways_20260211%WP188%Rattus norvegicus Focal adhesion 29220 25567 29169 116669 117036 25313 360457 24446 24482 25266 94203 294754 25021 24511 309684 311061 295347 171337 85385 114858 114636 25404 29161 25150 81504 83805 170922 363425 81634 29195 290905 85490 29393 84352 24477 192362 24718 25353 364403 24329 24337 79113 54251 25734 25718 24553 25267 24629 296472 305311 170908 303882 114509 114495 60352 116590 58960 303200 170851 25614 299012 360820 29153 81745 24185 25233 81762 25537 314641 117558 81822 287876 100361457 84027 25513 29741 50557 363875 366957 29431 29433 29432 79429 89811 114111 25414 54245 63881 64465 64639 50658 24516 58919 64033 25654 294279 306628 361821 25304 309368 307582 309816 140433 298941 305078 445442 292406 681309 116640 363458 304913 311862 24628 25589 366275 500340 303247 362800 257645 29302 83577 296456 308995 64350 499271 364786 685004 310683 315744 685269 114517 311144 360606 685269 313494 170911 366508 298947 497931 116554 307483 313845 81649 293621 305679 361517 309081 24703 114486 114486 29360 54268 314436 29414 116670 288057 292756 296078 311450 Glucocorticoid effect on target gene expression%WikiPathways_20260211%WP1963%Rattus norvegicus Glucocorticoid effect on target gene expression 260321 500598 26198 24653 24413 266759 361568 81736 25493 25380 83514 81736 VEGFR 3 signaling%WikiPathways_20260211%WP1964%Rattus norvegicus VEGFR 3 signaling 58918 50689 25738 24185 116590 114110 85385 308451 298947 114111 360457 81504 64639 24600 VEGF receptor signal transduction%WikiPathways_20260211%WP1965%Rattus norvegicus VEGF receptor signal transduction 60664 24680 81504 25738 310688 24185 114111 89811 85385 24703 360820 83805 289014 246146 85385 84006 116590 116590 64639 58918 24600 363875 94203 Genetic alterations of lung cancer%WikiPathways_20260211%WP1968%Rattus norvegicus Genetic alterations of lung cancer 170911 24337 24329 116590 170851 24703 305302 24185 311807 59086 50554 29357 81809 58919 24708 399489 311562 25312 314856 54244 24842 25729 114851 366508 Serotonin and anxiety%WikiPathways_20260211%WP2132%Rattus norvegicus Serotonin and anxiety 29412 24412 29595 54323 116647 364206 24674 24473 25187 25023 314322 81648 Brain derived neurotrophic factor%WikiPathways_20260211%WP2148%Rattus norvegicus Brain derived neurotrophic factor 24225 24225 25054 25692 24617 116590 24596 85253 170851 24703 24225 Nuclear receptors%WikiPathways_20260211%WP217%Rattus norvegicus Nuclear receptors 361801 293701 24706 24413 60349 50659 54278 684085 113984 24873 83826 24831 259241 81812 368158 83574 25682 81808 25664 362550 25271 25149 58851 58852 24705 24890 84385 245980 25747 25735 299210 65035 Osteoblast signaling%WikiPathways_20260211%WP227%Rattus norvegicus Osteoblast signaling 24694 117516 25295 25267 170583 29393 25548 25295 24629 Nuclear factor erythroid derived 2 like 2 signaling pathway%WikiPathways_20260211%WP2376%Rattus norvegicus Nuclear factor erythroid derived 2 like 2 signaling pathway 83472 24681 287876 100361457 114851 24189 289990 305540 299602 84027 29437 116484 64188 295037 81822 313121 24605 24786 57298 310392 25522 25581 29741 499688 24424 295362 116686 304127 29739 25073 50689 24787 116554 114846 363855 25513 289021 681050 497932 361632 114495 497672 29677 25256 24778 25023 83619 65052 50658 81827 24680 29292 25319 114509 113894 289197 29702 499689 171341 25352 309465 85420 287642 246760 170851 84006 170915 83688 84509 24534 361568 117254 192255 64352 116590 85430 79130 116720 25375 24516 497931 313834 25260 293621 54244 24451 64191 291084 170538 81649 140668 170924 116643 24423 365355 170911 171445 117262 24842 26760 24565 116667 296972 29224 102556347 24377 29340 85252 29275 25365 295549 24426 25458 291796 25150 366508 289623 60664 297029 78959 24314 29487 25315 24703 81633 25445 Spinal cord injury%WikiPathways_20260211%WP2433%Rattus norvegicus Spinal cord injury 24596 287437 498666 25613 29190 289392 29364 79426 116591 257651 25167 24494 24599 287287 29619 24598 116562 24498 29260 314322 59086 24330 25712 24547 83765 362119 81503 25293 29221 316539 245920 25405 81687 58982 65047 360272 83467 114523 308739 25663 24493 114105 24770 360426 29354 29692 25380 25651 308565 24387 24807 116651 24708 24680 399489 311562 116590 58919 25112 50689 25402 24842 314694 114122 290905 64133 58968 25393 140586 24408 81818 24674 29423 25639 29409 295342 25537 450224 113912 65146 85431 100314002 54237 25453 361324 24392 24225 Sulindac metabolic pathway%WikiPathways_20260211%WP2541%Rattus norvegicus Sulindac metabolic pathway 24296 361286 29447 Relationship between glutathione and NADPH%WikiPathways_20260211%WP2562%Rattus norvegicus Relationship between glutathione and NADPH 29739 24377 292804 25290 246097 50555 192227 289827 289632 310378 114214 29292 501157 116554 24887 114851 24651 25402 498881 24383 303448 100360180 117548 83472 288562 116686 81641 291984 25319 24426 24333 24189 362383 290636 114097 24842 24644 24314 64678 24959 24645 83688 24565 24385 64524 25458 116484 25741 84359 365057 296654 Tryptophan metabolism%WikiPathways_20260211%WP270%Rattus norvegicus Tryptophan metabolism 66029 65210 313375 246281 60421 25120 314856 24311 63864 140547 364975 360975 171385 56823 116682 64206 24848 314442 24248 29416 298298 65183 25429 688283 65029 368066 24296 24894 24895 25053 25086 25426 685222 54246 56266 113965 24188 304500 29539 64040 361585 Monoamine GPCRs%WikiPathways_20260211%WP276%Rattus norvegicus Monoamine GPCRs 24448 24175 25324 29238 25461 24260 29412 25195 79247 25432 25645 24173 81645 64354 25323 25229 65032 25111 53949 25083 29595 60448 24316 25689 24925 24174 25187 24473 29413 Matrix metalloproteinases%WikiPathways_20260211%WP278%Rattus norvegicus Matrix metalloproteinases 94339 81686 25481 291848 81687 303384 29543 498028 288626 25246 65205 366964 81707 293573 25358 83513 24835 680130 mir219 in oligodendrocyte differentiation and myelination%WikiPathways_20260211%WP2811%Rattus norvegicus mir219 in oligodendrocyte differentiation and myelination 361895 313554 25267 29458 64619 293165 79225 Pentose phosphate pathway%WikiPathways_20260211%WP282%Rattus norvegicus Pentose phosphate pathway 24377 290636 501157 83688 362383 64524 100360180 117548 p38 Mapk signaling pathway%WikiPathways_20260211%WP294%Rattus norvegicus p38 Mapk signaling pathway 289014 81504 311786 498183 24471 85385 114495 500690 363875 29591 81518 81647 365057 500526 313121 306886 314384 81649 314436 60661 293621 64465 24653 287398 81809 140926 116667 246756 Proteasome degradation%WikiPathways_20260211%WP302%Rattus norvegicus Proteasome degradation 498560 29669 29630 94198 29672 287772 81827 81816 24968 307821 58854 81920 303353 25596 29677 29675 24967 29545 287670 365388 64701 289924 29674 100360846 29425 296651 361831 289990 117262 83499 29614 85492 25581 287984 292766 81827 Prostaglandin synthesis and regulation%WikiPathways_20260211%WP303%Rattus norvegicus Prostaglandin synthesis and regulation 24326 29527 50672 25527 81778 24683 79242 85247 25291 24886 306283 292661 25673 25116 24653 24693 25526 25380 498475 29680 79124 25637 25117 84023 25652 79125 25575 81752 24929 24323 Glucocorticoid metabolism%WikiPathways_20260211%WP305%Rattus norvegicus Glucocorticoid metabolism 25117 191574 25116 29680 25146 24298 Striated muscle contraction%WikiPathways_20260211%WP316%Rattus norvegicus Striated muscle contraction 29248 29388 81633 287876 100361457 171409 29437 29389 295929 29556 290561 500450 296369 81818 117557 363925 311029 171009 252942 29275 24583 24852 84015 24838 24837 296313 292879 63836 25566 291245 IL 3 signaling pathway%WikiPathways_20260211%WP319%Rattus norvegicus IL 3 signaling pathway 24495 246144 171081 170911 366508 293621 84492 84598 24514 116689 25622 81515 25155 25734 25150 313050 24918 25126 25125 24705 25271 25513 29741 24185 361597 83427 25023 85385 25577 56011 84477 81504 313845 361388 63881 287942 54245 64639 24888 24887 64547 24672 25614 360820 83805 89829 140694 305679 24703 170851 363875 366957 116554 116590 50689 25159 25636 29431 24680 81736 24778 50686 84027 65199 114509 84482 24471 81649 81647 361696 295347 64041 289014 366126 64465 367786 156767 25261 25651 171075 50658 140583 60450 81686 81687 TCA cycle%WikiPathways_20260211%WP347%Rattus norvegicus TCA cycle 360975 298942 289217 296849 298596 25104 24551 289950 157074 81829 362404 114597 26955 361071 29554 89813 24368 94173 81530 G1 to S cell cycle control%WikiPathways_20260211%WP348%Rattus norvegicus G1 to S cell cycle control 24708 684111 399489 311562 304573 83571 114483 25737 114851 65131 54237 24842 246060 116651 25729 310616 25164 314856 171150 29157 59102 100360427 298400 362291 25203 58919 84389 100362927 29728 406169 313479 29685 288532 312538 313138 54238 299112 266713 291927 291885 313978 291105 361178 287524 680111 308937 362165 25112 85242 295596 295052 362304 362485 Synthesis and degradation of ketone bodies%WikiPathways_20260211%WP349%Rattus norvegicus Synthesis and degradation of ketone bodies 79238 24450 690163 117099 Regulation of actin cytoskeleton%WikiPathways_20260211%WP351%Rattus norvegicus Regulation of actin cytoskeleton 89812 116590 24260 309419 296654 304580 29431 64303 65052 60662 25266 363460 497931 85384 117542 361598 305679 25443 60323 114559 303634 79433 81645 25229 289021 25444 24329 360891 303342 306400 313024 311450 170851 65172 29348 81663 58823 63851 81822 29741 29432 25114 170633 53949 170630 64465 81814 116720 25313 25414 288057 365396 116499 25513 29433 309081 25111 366624 60350 24629 360854 170911 25614 66017 29368 117273 24782 84489 361632 170583 170582 29369 116723 24605 54250 60664 54319 81762 287876 100361457 60464 298947 363509 363875 114486 365355 361568 24205 293623 25267 84488 365865 294568 292756 114120 313845 54245 24506 25118 24703 315707 50689 303073 360820 24505 25022 366508 296078 83709 29271 24559 170700 25317 29251 25439 79114 170632 29349 54268 IL 1 signaling pathway%WikiPathways_20260211%WP355%Rattus norvegicus IL 1 signaling pathway 24494 60582 25466 25663 24493 117022 300177 314870 361677 305549 313121 315139 116554 360640 309361 140934 113894 25522 25528 25622 362418 29153 29156 116590 24185 311245 25493 81525 170851 50689 309165 81736 25738 300177 MAPK signaling pathway%WikiPathways_20260211%WP358%Rattus norvegicus MAPK signaling pathway 311245 499497 501560 304786 295347 54245 24493 29414 303823 170668 313121 50658 81504 500526 29332 314436 24329 24675 171378 292763 100361818 25388 29477 29434 60350 309295 24225 140926 25272 24559 311622 81649 84351 25387 25402 293860 289014 25625 360640 24471 311743 81663 59086 116667 171492 63995 114513 301363 24629 308106 25112 171103 25663 170538 65179 170851 363875 246781 117022 308267 29591 116590 29644 691905 114486 59109 81647 287398 314322 24681 85384 81809 60587 140724 116457 24494 311786 29513 286993 114495 361679 25233 498183 79114 25717 24674 25313 313022 116596 310738 287942 64666 50689 116554 24680 25730 25266 25054 25385 24629 24667 25022 64465 84489 362045 25114 24516 313845 24518 361568 293621 24842 365355 81736 114120 691810 24592 361714 24185 313874 170668 25676 81737 310533 293508 25636 498003 170920 309361 309452 293694 309165 363855 100360982 293847 497961 303330 311406 297682 246097 24653 361400 365057 309168 304530 361715 302983 306204 362332 24963 24605 24703 691907 311341 296091 140726 140725 306243 140729 140728 25398 257648 24239 29716 54234 114493 682930 25399 50688 116600 58942 29658 114862 29717 312668 116499 25317 54250 170633 116499 60662 170700 29348 29349 25444 25443 170632 170630 84488 63851 66017 29369 29368 60464 170582 29432 29431 Acetylcholine synthesis%WikiPathways_20260211%WP360%Rattus norvegicus Acetylcholine synthesis 140544 29554 25373 83817 25511 Wnt myofibroblastic activation of hepatic stellate cells%WikiPathways_20260211%WP3649%Rattus norvegicus Wnt myofibroblastic activation of hepatic stellate cells 25664 303181 Acetate mediated promotion of metabolic syndrome%WikiPathways_20260211%WP3650%Rattus norvegicus Acetate mediated promotion of metabolic syndrome 25320 24506 Beta oxidation meta pathway%WikiPathways_20260211%WP372%Rattus norvegicus Beta oxidation meta pathway 170670 364975 24539 113965 24849 140547 25363 25757 311569 50682 25288 311849 25014 171155 361676 25062 114024 298942 94340 64304 25413 25330 113976 117243 24158 Wnt signaling pathway%WikiPathways_20260211%WP375%Rattus norvegicus Wnt signaling pathway 364754 54237 64462 24246 306862 361765 303251 310704 64566 24882 307641 50689 24205 50554 503000 24703 83721 84027 81679 117526 293897 287280 116590 84353 64053 293992 29495 117273 25387 50658 81717 307511 116549 79128 289229 313121 171140 116457 24672 293649 25422 161452 84402 64512 245903 24680 497961 303330 363875 78973 25023 307740 64558 114487 266608 25388 24185 25400 362356 29134 362342 29382 60328 79257 83824 29456 312781 58919 84426 310552 114850 24681 83826 24245 361374 116554 360564 303181 84382 140586 83502 25252 306782 364952 65137 81650 500430 113927 24516 303811 Renin angiotensin system%WikiPathways_20260211%WP376%Rattus norvegicus Renin angiotensin system 314322 24310 309295 25679 24516 29432 25262 296370 24590 116590 81678 81504 116667 64017 85420 25272 311450 50658 84351 25614 292756 50689 290257 25153 81641 81647 24514 309165 25125 24654 54242 296078 116554 171105 363875 302668 292661 50646 117041 24179 24182 25627 24703 25636 29433 24180 29513 85385 116554 287398 24715 29431 363855 314436 170911 GPCRs class B secretin like%WikiPathways_20260211%WP378%Rattus norvegicus GPCRs class B secretin like 64124 361383 24953 25024 316137 116506 25321 170641 58959 81779 64680 24875 65096 171447 25051 60432 24167 25029 Proximal tubule transporters%WikiPathways_20260211%WP3881%Rattus norvegicus Proximal tubule transporters 24784 59114 116501 311651 54231 291819 29242 791259 288360 64076 29509 83500 25548 84395 29502 58980 84484 65202 64846 24211 25650 64190 664630 25550 291840 307811 29726 116726 83509 84551 170566 685232 312488 117596 299159 297566 298103 289407 297797 29757 116455 689779 117252 296981 170667 291969 297932 436582 Thick ascending limb transporters%WikiPathways_20260211%WP3882%Rattus norvegicus Thick ascending limb transporters 24784 117955 25065 24211 79430 308069 25240 79430 54231 29242 25650 64119 84020 29719 79425 24783 Angiotensin II signaling acute in thick ascending limbs%WikiPathways_20260211%WP3887%Rattus norvegicus Angiotensin II signaling acute in thick ascending limbs 25679 25262 81678 24680 29337 81666 24182 24180 81638 298646 25388 140694 25738 24600 50663 24244 85431 85431 24681 81743 24600 81745 25153 25636 50557 25233 24185 29414 Fructose metabolism in proximal tubules%WikiPathways_20260211%WP3894%Rattus norvegicus Fructose metabolism in proximal tubules 24189 292804 361730 24788 24362 25634 287716 25741 24192 25659 24190 24849 25058 60416 25058 303205 65197 366441 337920 Lipid droplet metabolism%WikiPathways_20260211%WP3901%Rattus norvegicus Lipid droplet metabolism 298199 680423 25288 361722 311617 114024 361676 84497 252900 81782 25055 296130 294324 406165 170919 311821 306582 313977 362261 25062 Hexoses metabolism in proximal tubules%WikiPathways_20260211%WP3916%Rattus norvegicus Hexoses metabolism in proximal tubules 25351 24849 25552 65197 24644 292804 298942 24642 246311 289950 311254 498881 24383 24651 171087 29554 24189 54705 64522 25058 24191 24190 100359982 116551 296849 81530 89813 25104 24159 25741 60416 361730 24788 25659 24192 25634 287716 24959 24333 25438 24334 362282 24401 25721 81829 24551 24534 24533 303205 366441 24362 ID signaling pathway%WikiPathways_20260211%WP397%Rattus norvegicus ID signaling pathway 25261 25587 25585 291023 24708 81758 680111 337868 114494 25729 314436 304786 83499 29577 293992 81819 299766 29148 78968 312897 29373 54251 25589 25671 50554 59328 25389 313050 25718 24482 301965 81736 309165 25644 84349 310738 25313 679869 Inflammatory response pathway%WikiPathways_20260211%WP40%Rattus norvegicus Inflammatory response pathway 56822 156767 25712 29169 116562 25084 25746 313050 298941 103690850 140924 287287 171369 29393 192362 84352 84349 25625 25408 25704 117036 140433 445442 24497 114103 GPCRs other%WikiPathways_20260211%WP409%Rattus norvegicus GPCRs other 24326 57305 679957 117257 54258 362547 60590 29238 310444 260326 170641 445269 314213 25369 362436 60448 170704 24414 64443 25439 25449 81645 494319 81668 25321 293370 29413 25432 29595 405331 25248 29733 25706 294807 192649 498233 767613 65032 679975 287511 24938 25273 56821 60463 114098 24260 293374 25652 171447 366274 405137 294123 294121 117029 287480 83465 54305 310780 295144 Beta oxidation of unsaturated fatty acids%WikiPathways_20260211%WP418%Rattus norvegicus Beta oxidation of unsaturated fatty acids 170670 24158 29740 171155 117543 GPCRs class C metabotropic glutamate pheromone%WikiPathways_20260211%WP42%Rattus norvegicus GPCRs class C metabotropic glutamate pheromone 83633 24419 60590 293546 81657 312790 24414 24417 24415 500349 287805 24418 81672 24247 24416 Insulin induced PI3K Akt and MAPK in hepatocytes%WikiPathways_20260211%WP4229%Rattus norvegicus Insulin induced PI3K Akt and MAPK in hepatocytes 498416 29376 64226 64639 24159 116590 313845 84482 690987 85385 117045 292887 83840 50689 25623 60445 304298 303158 65052 24185 26954 50686 81771 287871 116636 24640 24703 24855 56718 29304 81504 24505 Ethanol metabolism resulting in production of ROS by CYP2E1%WikiPathways_20260211%WP4268%Rattus norvegicus Ethanol metabolism resulting in production of ROS by CYP2E1 116554 25086 64188 170851 83619 25023 Insulin signaling%WikiPathways_20260211%WP439%Rattus norvegicus Insulin signaling 81804 366508 65052 116693 360406 363875 84027 24714 303259 81504 114858 24778 361715 84351 301363 81749 117550 361512 81675 25233 171492 25532 170538 24185 64185 26954 25558 60352 25513 365057 29376 116720 29741 25272 303604 292763 50689 501560 50557 314436 85385 54245 246273 303443 317203 24954 289754 84482 116636 306117 25023 363855 361696 313845 366957 314322 298947 83521 171498 114203 29513 690987 24855 293692 116667 170920 85496 114495 100362311 25139 116596 25741 60445 314384 81803 25718 25522 25012 287398 58844 85420 81771 117269 81649 83840 309168 78975 64630 24697 287871 116554 65038 171136 313121 114095 80849 29517 689314 50658 25622 25623 24516 252971 117045 314612 83764 292699 65261 361388 299145 50686 84006 65248 686098 85384 303823 500036 24703 64310 56718 24680 25330 54268 293694 81745 293621 63881 294515 498416 24330 308463 24803 361632 116590 64665 170851 313022 171497 308106 500690 84392 503027 58960 360640 IL 5 signaling pathway%WikiPathways_20260211%WP44%Rattus norvegicus IL 5 signaling pathway 81647 25126 24887 309684 84027 25021 287942 294515 25513 25734 114203 29741 314612 83571 50646 114103 25155 25290 81736 85385 25023 364712 84598 116590 81504 25493 24653 252971 24516 24918 29402 170538 314436 293621 24497 298947 50689 25125 81771 63881 24514 84353 24185 288077 24703 25622 50686 29624 367901 313644 81649 116689 50658 24649 83841 81515 363875 Hypertrophy model%WikiPathways_20260211%WP442%Rattus norvegicus Hypertrophy model 360950 116636 25663 58853 24493 25712 117045 25389 25705 24518 83476 27064 365977 25433 29596 29148 TNF alpha NF kB signaling pathway%WikiPathways_20260211%WP457%Rattus norvegicus TNF alpha NF kB signaling pathway 305240 305751 292747 81525 83840 140934 64314 363984 361029 307449 361055 309295 25404 29476 116667 29677 29155 116596 289831 24185 81650 29753 303024 58934 84027 24835 362356 361925 306886 309165 303602 287772 310877 156767 303285 24672 116549 311786 362607 304005 25493 25573 287367 312937 293960 25576 682457 311245 308267 246240 307821 25069 266610 361765 81736 25625 291885 287707 293860 84577 313245 252961 360640 353256 361810 161477 64640 100362027 306007 25402 56010 363599 499374 361167 309452 361825 83427 171492 305451 305606 305584 309361 25233 313128 498206 56011 140657 303518 315713 362491 84351 361711 24471 266764 361388 297893 365388 29542 312641 83614 84020 303604 25636 54244 25581 680493 83805 25522 299602 288532 29355 304294 641452 353233 81774 25614 25586 246756 83581 680611 50659 307641 287670 289924 681193 64026 304893 83582 60328 116633 85245 117042 685607 64322 313867 25622 362247 29425 Glutathione metabolism%WikiPathways_20260211%WP469%Rattus norvegicus Glutathione metabolism 81641 116568 64317 24377 116686 25458 116568 116684 29326 57298 499688 24424 295362 25260 29487 57298 29566 29739 GPCRs class A rhodopsin like%WikiPathways_20260211%WP473%Rattus norvegicus GPCRs class A rhodopsin like 287481 310869 301086 317219 25601 116677 170926 60448 294187 25248 64020 685243 767613 117264 29234 25354 299588 64636 288181 252939 25555 83683 29597 500317 288995 54305 25432 81645 25593 29256 114211 292409 29335 116498 25637 84023 306307 25652 298394 57302 25083 25324 293375 29290 25264 64042 192223 312787 298944 24717 25439 25369 690158 405362 25033 60669 24175 25370 100911796 365228 83567 289180 58949 50577 24180 25111 291361 81752 294204 25342 295734 117549 64021 24173 117097 25477 25265 25689 293370 24925 314386 64354 24929 29358 65140 299242 310444 365523 117027 24938 24473 405140 60451 302373 29238 78964 297952 292661 498289 297795 246075 81644 689936 287511 308163 25449 445269 100909648 29462 54258 171108 266769 289239 292413 24613 85268 309212 302378 29316 29636 294138 295822 266607 140473 25706 25340 25645 29412 292794 405280 29235 29595 24260 260319 24326 287516 60463 305711 83518 282839 25195 689917 691774 24816 29413 408199 29310 498475 114099 171104 308408 24174 366274 24182 84007 25635 65275 25229 24448 29471 363682 84022 293364 405331 64107 65032 25461 64803 25187 688737 25153 25726 24316 679957 24889 50672 81509 294197 287480 25245 302954 66024 171044 25323 405138 60628 498434 117029 80840 287673 363993 282832 294203 53949 Apoptosis modulation by HSP70%WikiPathways_20260211%WP487%Rattus norvegicus Apoptosis modulation by HSP70 24472 116667 25385 25625 25402 25309 64625 81736 266610 58918 25272 83533 306886 64314 64026 83584 246097 Osteoclast%WikiPathways_20260211%WP489%Rattus norvegicus Osteoclast 116469 117516 24481 24782 297566 304695 288264 29302 29175 25353 Nucleotide GPCRs%WikiPathways_20260211%WP502%Rattus norvegicus Nucleotide GPCRs 691774 25369 29290 117264 29597 25265 302378 29316 Fatty acid biosynthesis%WikiPathways_20260211%WP504%Rattus norvegicus Fatty acid biosynthesis 25288 298381 50671 684538 116719 60581 114024 140547 246074 24159 29470 94340 113965 361465 117243 311569 25104 117543 170465 Burn wound healing%WikiPathways_20260211%WP5057%Rattus norvegicus Burn wound healing 64152 27064 25527 29316 81687 25556 246310 25155 24804 24842 117257 171103 24494 25402 29393 290905 64032 311332 29437 24335 316033 25266 24516 24482 25325 Biosynthesis of aldosterone and cortisol%WikiPathways_20260211%WP508%Rattus norvegicus Biosynthesis of aldosterone and cortisol 29632 25146 24294 24298 Catecholamine synthesis%WikiPathways_20260211%WP513%Rattus norvegicus Catecholamine synthesis 25699 24616 25085 24311 24661 Notch signaling pathway%WikiPathways_20260211%WP517%Rattus norvegicus Notch signaling pathway 303101 81751 362268 303811 500847 114125 29147 297893 29146 304591 29419 170905 360801 303251 54244 498089 303539 365872 56761 29492 83721 311332 292732 60433 289231 406162 25496 29382 315119 79225 29577 293774 29192 81717 G13 signaling pathway%WikiPathways_20260211%WP520%Rattus norvegicus G13 signaling pathway 29355 366624 308516 60323 308666 100360623 361598 366508 362456 306417 65172 83708 363875 303882 29433 116723 25272 682507 29741 25594 308106 83620 81762 307483 64465 83840 25537 mRNA processing%WikiPathways_20260211%WP529%Rattus norvegicus mRNA processing 298095 100361269 291295 687711 689116 313131 291794 299620 362229 294232 116655 29428 287643 362361 192246 680891 319110 366276 499958 500538 288701 290666 100359574 292019 295607 362223 308650 313056 117280 362829 84474 361811 687575 117259 117282 308472 116650 291078 362160 689890 311166 361035 362264 59087 293671 252855 361995 362630 362178 314417 79256 298916 83498 499390 299284 116697 60421 304277 304431 361814 305479 293505 362630 84599 299256 366952 494445 259229 291877 295270 683927 292007 56763 362612 65169 365842 287530 313583 287269 499420 84473 307540 29667 171552 29497 311670 308335 362687 304859 361126 313620 291534 100362099 361859 302855 171365 63996 361574 298075 287727 171305 310820 287739 362251 292729 140931 317385 289693 Complement and coagulation cascades%WikiPathways_20260211%WP547%Rattus norvegicus Complement and coagulation cascades 289055 79126 302470 64459 25584 25692 25619 64036 24617 294257 24231 81750 29687 54243 29333 289395 117512 54249 24237 304929 304917 83580 25087 24903 294257 24231 116669 362634 295703 50692 298566 155012 287527 290757 29436 64023 84007 25268 24233 25439 54243 29333 24153 313421 79224 25407 29251 113936 25048 24366 85253 24946 306761 312705 29243 192262 24548 260320 ACE inhibitor pathway%WikiPathways_20260211%WP557%Rattus norvegicus ACE inhibitor pathway 24310 24600 25087 24903 24179 81638 24182 24715 25245 IL 2 signaling pathway%WikiPathways_20260211%WP569%Rattus norvegicus IL 2 signaling pathway 116562 25126 25326 54245 304063 81515 24185 301965 25622 83427 252971 24918 366508 117045 498798 313050 25704 24703 24251 56718 288516 84598 81504 170851 25155 500526 25513 89829 290364 116554 84477 25125 309361 50646 24514 500538 29741 24413 24654 309165 170911 103690850 140924 311030 81736 25522 311021 25150 50658 289014 116590 83840 298947 287942 313845 81649 50689 294515 116689 85385 29376 Hedgehog signaling pathway%WikiPathways_20260211%WP574%Rattus norvegicus Hedgehog signaling pathway 366452 29499 54237 89830 25273 140588 313757 361769 290284 363067 140589 54244 25255 304729 25203 24483 291936 Cardiovascular signaling%WikiPathways_20260211%WP590%Rattus norvegicus Cardiovascular signaling 24185 25313 24472 24337 29393 29360 290905 116669 114559 83685 24471 29332 64314 296603 116640 360457 116466 365355 25267 25402 114495 29271 83584 85490 94203 292406 116554 306628 25654 114487 294568 Cholesterol metabolism%WikiPathways_20260211%WP632%Rattus norvegicus Cholesterol metabolism 29637 81782 25073 29580 25675 25728 81727 64191 78968 292697 81681 83791 100360417 24539 25292 81726 89784 140910 ATM signaling pathway%WikiPathways_20260211%WP654%Rattus norvegicus ATM signaling pathway 24708 680110 24842 24887 298795 25309 58919 25203 114483 114212 25729 58918 497672 399489 311562 114851 25402 54237 492821 25112 116502 p53 pathway%WikiPathways_20260211%WP655%Rattus norvegicus p53 pathway 116589 298795 24855 54237 301013 64394 24842 114212 680110 362931 83628 50557 114851 24484 492821 64625 25112 292949 24617 25309 25203 25405 24887 58918 304798 294518 287585 25163 246097 362675 25402 140941 140941 114483 140583 289508 25729 p53 signal pathway%WikiPathways_20260211%WP656%Rattus norvegicus p53 signal pathway 25402 24887 314856 300126 58918 64625 24482 24484 680110 24842 54237 25591 317389 492821 291005 317673 292949 246097 140941 25729 Steroid biosynthesis%WikiPathways_20260211%WP66%Rattus norvegicus Steroid biosynthesis 24470 24470 117182 360348 29632 79243 289055 25322 25146 29632 24470 79244 29540 G protein signaling pathways%WikiPathways_20260211%WP73%Rattus norvegicus G protein signaling pathways 24679 140929 64508 64532 114120 64199 116633 171378 114124 25521 24896 170538 60449 81666 50664 24627 25023 361568 309242 25740 54223 309962 24605 685451 680149 81667 25725 24674 25686 293508 50599 29322 361458 303634 312720 81529 81742 81636 24611 313834 302950 305509 293024 308776 83425 117273 79254 25643 498549 85420 298024 290646 245986 29340 24681 24400 24680 84006 79218 114117 293621 25522 60323 360540 29241 84420 25636 24626 81744 246150 81663 25262 24782 Integrin mediated cell adhesion%WikiPathways_20260211%WP74%Rattus norvegicus Integrin mediated cell adhesion 311144 116694 170922 25614 29302 83577 313845 114636 295347 25021 54245 171495 64350 29360 81762 296456 360606 305679 63881 685269 83685 366957 360820 296078 170851 25414 25724 362800 81745 29155 83805 309081 295378 114486 363425 308995 499271 25118 25150 25272 29161 24717 293621 114509 25404 311061 85385 24511 29154 29414 58960 29741 685004 306260 310683 24703 296603 64465 29156 309684 29432 303200 116590 686098 171337 114495 29433 170921 25233 29153 363875 25537 304546 361517 114517 29431 24185 81504 257645 364786 315744 114559 117558 292756 54268 60352 313494 114858 IL 9 signaling pathway%WikiPathways_20260211%WP8%Rattus norvegicus IL 9 signaling pathway 25126 29376 89829 25125 170851 84598 103690850 140924 50689 24185 25513 192218 24500 25622 116558 24918 81504 116643 85385 25326 116590 Hepatocyte growth factor receptor signaling%WikiPathways_20260211%WP94%Rattus norvegicus Hepatocyte growth factor receptor signaling 63881 24703 171337 83805 25614 54245 50646 360820 361388 50557 24446 58960 25676 292763 24553 170851 25118 314436 295347 116590 29431 116554 170911 287942 25125 293621 313845 24516 81504 24511 309081 25622 50689 314322