ALANINE METABOLISM%SMPDB%SMP0000055 Alanine Metabolism 189 2875 51660 5091 57505 ASPARTATE METABOLISM%SMPDB%SMP0000067 Aspartate Metabolism 18 2571 790 440 122622 443 259307 158 445 435 8528 4677 1615 80150 GLUTAMATE METABOLISM%PATHWHIZ%PW000003 Glutamate Metabolism 2730 124454 55577 2673 8659 8833 2806 2729 2937 2936 5859 7915 5471 64841 18 1373 2571 790 2746 27165 2875 2752 GLUTATHIONE METABOLISM%SMPDB%SMP0000015 Glutathione Metabolism 119391 26873 290 2729 2937 2936 2876 124975 840 79017 2730 CITRIC ACID CYCLE%SMPDB%SMP0000057 Citric Acid Cycle 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 ALPHA LINOLENIC ACID AND LINOLEIC ACID METABOLISM%PATHWHIZ%PW000006 Alpha Linolenic Acid and Linoleic Acid Metabolism 100137049 9415 3992 6785 60481 SELENOAMINO ACID METABOLISM%PATHWHIZ%PW000007 Selenoamino Acid Metabolism 875 27430 22928 9061 191 64116 131965 1491 2678 4141 51540 4144 AMINO SUGAR METABOLISM%PATHWHIZ%PW000008 Amino Sugar Metabolism 51005 5238 140838 55907 64841 10020 6675 3098 26503 3073 1118 10007 54187 80896 55577 2673 5973 AMMONIA RECYCLING%PATHWHIZ%PW000009 Ammonia Recycling 343 2731 2752 1373 3034 1738 10993 80150 2746 440 275 27165 ARGININE AND PROLINE METABOLISM%SMPDB%SMP0000020 Arginine and Proline Metabolism 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 BETA-ALANINE METABOLISM%SMPDB%SMP0000007 beta-Alanine Metabolism 4329 8639 84735 18 217 1807 1806 2571 51733 BETAINE METABOLISM%SMPDB%SMP0000123 Betaine Metabolism 4144 501 27430 635 191 55349 10400 4548 BIOTIN METABOLISM%SMPDB%SMP0000066 Biotin Metabolism 686 28972 3141 32 BUTYRATE METABOLISM%PATHWHIZ%PW000014 Butyrate Metabolism 116285 35 38 1892 3155 3033 5019 CAFFEINE METABOLISM%SMPDB%SMP0000028 Caffeine Metabolism 1558 1544 1576 7498 1571 10 1548 1559 CARNITINE SYNTHESIS%SMPDB%SMP0000465 Carnitine Synthesis 223 8424 80854 55217 6470 CATECHOLAMINE BIOSYNTHESIS%SMPDB%SMP0000012 Catecholamine Biosynthesis 5409 7054 1644 CYSTEINE METABOLISM%PATHWHIZ%PW000018 Cysteine Metabolism 2805 1491 3939 2730 1036 1497 833 4357 2729 D-ARGININE AND D-ORNITHINE METABOLISM%PATHWHIZ%PW000019 D-Arginine and D-Ornithine Metabolism 1610 DEGRADATION OF SUPEROXIDES%PATHWHIZ%PW000020 Degradation of Superoxides 6647 847 7306 6649 6648 ETHANOL DEGRADATION%PATHWHIZ%PW000021 Ethanol Degradation 125 84532 217 55902 1571 219 847 FATTY ACID ELONGATION IN MITOCHONDRIA%SMPDB%SMP0000054 Fatty Acid Elongation in Mitochondria 10449 3028 51102 1892 3032 3030 5538 FATTY ACID METABOLISM%PATHWHIZ%PW000023 Fatty Acid Metabolism 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 FOLATE METABOLISM%SMPDB%SMP0000053 Folate Metabolism 1719 4522 8836 4524 10840 10841 10797 10588 25902 2356 113235 123263 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0000064 Fructose and Mannose Degradation 229 5207 197258 29085 7264 5372 7167 4351 6652 5211 3098 8790 29925 231 2203 2762 226 3795 GLYCEROL PHOSPHATE SHUTTLE%SMPDB%SMP0000124 Glycerol Phosphate Shuttle 2820 2597 2819 HOMOCYSTEINE DEGRADATION%SMPDB%SMP0000455 Homocysteine Degradation 875 1491 KETONE BODY METABOLISM%PATHWHIZ%PW000028 Ketone Body Metabolism 38 622 3155 5019 LYSINE DEGRADATION%PATHWHIZ%PW000029 Lysine Degradation 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 MALATE-ASPARTATE SHUTTLE%PATHWHIZ%PW000030 Malate-Aspartate Shuttle 8402 8604 2806 4191 NUCLEOTIDE SUGARS METABOLISM%PATHWHIZ%PW000031 Nucleotide Sugars Metabolism 80146 2645 7358 5236 2584 2582 2592 7360 PANTOTHENATE AND COA BIOSYNTHESIS%SMPDB%SMP0000027 Pantothenate and CoA Biosynthesis 8876 5167 80347 53354 79717 60490 PHENYLACETATE METABOLISM%SMPDB%SMP0000126 Phenylacetate Metabolism 116285 10249 348158 PYRUVALDEHYDE DEGRADATION%SMPDB%SMP0000459 Pyruvaldehyde Degradation 3029 2739 197257 RIBOFLAVIN METABOLISM%SMPDB%SMP0000070 Riboflavin Metabolism 7299 5167 55312 80308 52 THIAMINE METABOLISM%SMPDB%SMP0000076 Thiamine Metabolism 27010 79178 10560 84284 SPERMIDINE AND SPERMINE BIOSYNTHESIS%PATHWHIZ%PW000037 Spermidine and Spermine Biosynthesis 4144 27430 6611 4953 6723 262 TAURINE AND HYPOTAURINE METABOLISM%SMPDB%SMP0000021 Taurine and Hypotaurine Metabolism 124975 1036 2571 84890 51380 UBIQUINONE BIOSYNTHESIS%SMPDB%SMP0000065 Ubiquinone Biosynthesis 51805 10229 27235 51004 84274 SULFATE SULFITE METABOLISM%PATHWHIZ%PW000040 Sulfate Sulfite Metabolism 6817 10380 6821 6820 9060 50515 PHYTANIC ACID PEROXISOMAL OXIDATION%PATHWHIZ%PW000041 Phytanic Acid Peroxisomal Oxidation 5264 224 225 215 11001 26061 PHENYLALANINE AND TYROSINE METABOLISM%PATHWHIZ%PW000042 Phenylalanine and Tyrosine Metabolism 6898 3242 10056 2184 2805 2193 2954 5053 3081 259307 8565 HISTIDINE METABOLISM%SMPDB%SMP0000044 Histidine Metabolism 138199 10841 23438 26 10196 3035 144193 57571 3067 3034 131669 3176 84735 217 55748 218 4128 ARACHIDONIC ACID METABOLISM%SMPDB%SMP0000075 Arachidonic Acid Metabolism 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 ANDROGEN AND ESTROGEN METABOLISM%SMPDB%SMP0000068 Androgen and Estrogen Metabolism 412 6783 6820 6715 3283 3293 10720 3292 6718 1588 7367 1586 GLUCOSE-ALANINE CYCLE%SMPDB%SMP0000127 Glucose-Alanine Cycle 2746 79751 6509 55089 2875 6514 6517 84706 VITAMIN K METABOLISM%SMPDB%SMP0000464 Vitamin K Metabolism 2677 1728 79001 PHOSPHOLIPID BIOSYNTHESIS%SMPDB%SMP0000025 Phospholipid Biosynthesis 8611 9489 23761 26279 162466 1040 2820 54675 114971 5338 10554 81490 10434 1119 5130 23659 9791 57678 100137049 1103 51573 2819 1606 10400 10423 LACTOSE SYNTHESIS%SMPDB%SMP0000444 Lactose Synthesis 2592 124583 2538 7360 51727 3906 7355 6513 2683 4831 STEROID BIOSYNTHESIS%PATHWHIZ%PW000050 Steroid Biosynthesis 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 VALINE, LEUCINE, AND ISOLEUCINE DEGRADATION%PATHWHIZ%PW000051 Valine, Leucine, and Isoleucine Degradation 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 PURINE METABOLISM%PATHWHIZ%PW000052 Purine Metabolism 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 VITAMIN B6 METABOLISM%PATHWHIZ%PW000053 Vitamin B6 Metabolism 57026 8566 249 316 55163 PYRUVATE METABOLISM%PATHWHIZ%PW000054 Pyruvate Metabolism 217 5313 55902 5105 1738 2739 1737 97 31 197257 5162 134526 38 4199 9380 5091 4190 5160 231 3029 3939 PENTOSE PHOSPHATE PATHWAY%SMPDB%SMP0000031 Pentose Phosphate Pathway 6120 221823 22934 5211 25796 7086 51071 2821 2203 226 5236 5226 6888 64080 2539 METHIONINE METABOLISM%SMPDB%SMP0000033 Methionine Metabolism 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 PRIMARY HYPEROXALURIA TYPE I%SMPDB%SMP0000352 Primary Hyperoxaluria Type I 189 2875 51660 5091 57505 PYRUVATE CARBOXYLASE DEFICIENCY%SMPDB%SMP0000350 Pyruvate Carboxylase Deficiency 189 2875 51660 5091 57505 17-BETA HYDROXYSTEROID DEHYDROGENASE III DEFICIENCY%SMPDB%SMP0000356 17-beta Hydroxysteroid Dehydrogenase III Deficiency 412 6783 6820 6715 3283 3293 10720 3292 6718 1588 7367 1586 BETA-KETOTHIOLASE DEFICIENCY%SMPDB%SMP0000173 beta-Ketothiolase Deficiency 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 2-METHYL-3-HYDROXYBUTYRYL-COA DEHYDROGENASE DEFICIENCY%PATHWHIZ%PW000061 2-Methyl-3-hydroxybutyryl-CoA Dehydrogenase Deficiency 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 PROPIONIC ACIDEMIA%PATHWHIZ%PW000062 Propionic Acidemia 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 3-HYDROXY-3-METHYLGLUTARYL-COA LYASE DEFICIENCY%PATHWHIZ%PW000063 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 MAPLE SYRUP URINE DISEASE%PATHWHIZ%PW000064 Maple Syrup Urine Disease 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 3-METHYLCROTONYL-COA CARBOXYLASE DEFICIENCY TYPE I%SMPDB%SMP0000237 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 3-METHYLGLUTACONIC ACIDURIA TYPE I%SMPDB%SMP0000139 3-Methylglutaconic Aciduria Type I 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 3-METHYLGLUTACONIC ACIDURIA TYPE III%SMPDB%SMP0000140 3-Methylglutaconic Aciduria Type III 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 METHYLMALONATE SEMIALDEHYDE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000384 Methylmalonate Semialdehyde Dehydrogenase Deficiency 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 METHYLMALONIC ACIDURIA%SMPDB%SMP0000200 Methylmalonic Aciduria 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 4-HYDROXYBUTYRIC ACIDURIA SUCCINIC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000243 4-Hydroxybutyric Aciduria Succinic Semialdehyde Dehydrogenase Deficiency 2730 124454 55577 2673 8659 8833 2806 2729 2937 2936 5859 7915 5471 64841 18 1373 2571 790 2746 27165 2875 2752 HOMOCARNOSINOSIS%SMPDB%SMP0000385 Homocarnosinosis 2730 124454 55577 2673 8659 8833 2806 2729 2937 2936 5859 7915 5471 64841 18 1373 2571 790 2746 27165 2875 2752 HYPERINSULINISM-HYPERAMMONEMIA SYNDROME%PATHWHIZ%PW000072 Hyperinsulinism-Hyperammonemia Syndrome 2730 124454 55577 2673 8659 8833 2806 2729 2937 2936 5859 7915 5471 64841 18 1373 2571 790 2746 27165 2875 2752 GLUTATHIONE SYNTHETASE DEFICIENCY%PATHWHIZ%PW000073 Glutathione Synthetase Deficiency 119391 26873 290 2729 2937 2936 2876 124975 840 79017 2730 5-OXOPROLINURIA%PATHWHIZ%PW000074 5-Oxoprolinuria 119391 26873 290 2729 2937 2936 2876 124975 840 79017 2730 ADENOSINE DEAMINASE DEFICIENCY%PATHWHIZ%PW000075 Adenosine Deaminase Deficiency 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 ADENYLOSUCCINATE LYASE DEFICIENCY%SMPDB%SMP0000167 Adenylosuccinate Lyase Deficiency 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 GOUT OR KELLEY-SEEGMILLER SYNDROME%SMPDB%SMP0000365 Gout or Kelley-Seegmiller Syndrome 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 LESCH-NYHAN SYNDROME (LNS)%SMPDB%SMP0000364 Lesch-Nyhan Syndrome (LNS) 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 MOLYBDENUM COFACTOR DEFICIENCY%SMPDB%SMP0000203 Molybdenum Cofactor Deficiency 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 XANTHINE DEHYDROGENASE DEFICIENCY (XANTHINURIA)%SMPDB%SMP0000220 Xanthine Dehydrogenase Deficiency (Xanthinuria) 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 PURINE NUCLEOSIDE PHOSPHORYLASE DEFICIENCY%SMPDB%SMP0000210 Purine Nucleoside Phosphorylase Deficiency 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 AICA-RIBOSIDURIA%PATHWHIZ%PW000082 AICA-Ribosiduria 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 PROLIDASE DEFICIENCY (PD)%PATHWHIZ%PW000083 Prolidase Deficiency (PD) 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 ARGININE: GLYCINE AMIDINOTRANSFERASE DEFICIENCY (AGAT DEFICIENCY)%PATHWHIZ%PW000084 Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency) 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 HYPERPROLINEMIA TYPE II%SMPDB%SMP0000360 Hyperprolinemia Type II 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 HYPERPROLINEMIA TYPE I%SMPDB%SMP0000361 Hyperprolinemia Type I 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 PROLINEMIA TYPE II%PATHWHIZ%PW000087 Prolinemia Type II 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 GUANIDINOACETATE METHYLTRANSFERASE DEFICIENCY (GAMT DEFICIENCY)%SMPDB%SMP0000188 Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency) 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 ORNITHINE AMINOTRANSFERASE DEFICIENCY (OAT DEFICIENCY)%SMPDB%SMP0000363 Ornithine Aminotransferase Deficiency (OAT Deficiency) 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 AROMATIC L-AMINOACID DECARBOXYLASE DEFICIENCY%PATHWHIZ%PW000090 Aromatic L-Aminoacid Decarboxylase Deficiency 5409 7054 1644 ISOVALERIC ACIDURIA%PATHWHIZ%PW000091 Isovaleric Aciduria 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 BIOTINIDASE DEFICIENCY%SMPDB%SMP0000174 Biotinidase Deficiency 686 28972 3141 32 CANAVAN DISEASE%SMPDB%SMP0000175 Canavan Disease 18 2571 790 440 122622 443 259307 158 445 435 8528 4677 1615 80150 HYPOACETYLASPARTIA%PATHWHIZ%PW000094 Hypoacetylaspartia 18 2571 790 440 122622 443 259307 158 445 435 8528 4677 1615 80150 SMITH-LEMLI-OPITZ SYNDROME (SLOS)%PATHWHIZ%PW000095 Smith-Lemli-Opitz Syndrome (SLOS) 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 CHILD SYNDROME%PATHWHIZ%PW000096 CHILD Syndrome 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 DESMOSTEROLOSIS%PATHWHIZ%PW000097 Desmosterolosis 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 CHONDRODYSPLASIA PUNCTATA II, X-LINKED DOMINANT (CDPX2)%SMPDB%SMP0000388 Chondrodysplasia Punctata II, X-Linked Dominant (CDPX2) 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 LYSOSOMAL ACID LIPASE DEFICIENCY (WOLMAN DISEASE)%PATHWHIZ%PW000099 Lysosomal Acid Lipase Deficiency (Wolman Disease) 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 CYSTATHIONINE BETA-SYNTHASE DEFICIENCY%SMPDB%SMP0000177 Cystathionine beta-Synthase Deficiency 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 HYPERMETHIONINEMIA%SMPDB%SMP0000341 Hypermethioninemia 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 S-ADENOSYLHOMOCYSTEINE (SAH) HYDROLASE DEFICIENCY%PATHWHIZ%PW000102 S-Adenosylhomocysteine (SAH) Hydrolase Deficiency 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 GLYCINE N-METHYLTRANSFERASE DEFICIENCY%SMPDB%SMP0000222 Glycine N-Methyltransferase Deficiency 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY (MTHFRD)%SMPDB%SMP0000340 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 METHIONINE ADENOSYLTRANSFERASE DEFICIENCY%SMPDB%SMP0000221 Methionine Adenosyltransferase Deficiency 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 ETHYLMALONIC ENCEPHALOPATHY%PATHWHIZ%PW000106 Ethylmalonic Encephalopathy 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 GLUTARIC ACIDURIA TYPE I%SMPDB%SMP0000185 Glutaric Aciduria Type I 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 SHORT-CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (SCAD DEFICIENCY)%PATHWHIZ%PW000108 Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency) 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 GABA-TRANSAMINASE DEFICIENCY%SMPDB%SMP0000351 GABA-Transaminase Deficiency 4329 8639 84735 18 217 1807 1806 2571 51733 GAMMA-GLUTAMYLTRANSFERASE DEFICIENCY%PATHWHIZ%PW000110 gamma-Glutamyltransferase Deficiency 119391 26873 290 2729 2937 2936 2876 124975 840 79017 2730 GLUTARIC ACIDURIA TYPE I%SMPDB%SMP0000186 Glutaric Aciduria Type I 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 SACCHAROPINURIA HYPERLYSINEMIA II%SMPDB%SMP0000239 Saccharopinuria Hyperlysinemia II 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 HISTIDINEMIA%PATHWHIZ%PW000113 Histidinemia 138199 10841 23438 26 10196 3035 144193 57571 3067 3034 131669 3176 84735 217 55748 218 4128 LACTIC ACIDEMIA%PATHWHIZ%PW000114 Lactic Acidemia 189 2875 51660 5091 57505 LEIGH SYNDROME%SMPDB%SMP0000196 Leigh Syndrome 217 5313 55902 5105 1738 2739 1737 97 31 197257 5162 134526 38 4199 9380 5091 4190 5160 231 3029 3939 PYRUVATE DECARBOXYLASE E1 COMPONENT DEFICIENCY (PDHE1 DEFICIENCY)%SMPDB%SMP0000334 Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) 217 5313 55902 5105 1738 2739 1737 97 31 197257 5162 134526 38 4199 9380 5091 4190 5160 231 3029 3939 PYRUVATE DEHYDROGENASE COMPLEX DEFICIENCY%PATHWHIZ%PW000117 Pyruvate Dehydrogenase Complex Deficiency 217 5313 55902 5105 1738 2739 1737 97 31 197257 5162 134526 38 4199 9380 5091 4190 5160 231 3029 3939 LEUKOTRIENE C4 SYNTHESIS DEFICIENCY%PATHWHIZ%PW000118 Leukotriene C4 Synthesis Deficiency 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 PHENYLKETONURIA%PATHWHIZ%PW000119 Phenylketonuria 6898 3242 10056 2184 2805 2193 2954 5053 3081 259307 8565 TYROSINEMIA TYPE 2 (OR RICHNER-HANHART SYNDROME)%SMPDB%SMP0000369 Tyrosinemia Type 2 (or Richner-Hanhart Syndrome) 6898 3242 10056 2184 2805 2193 2954 5053 3081 259307 8565 TYROSINEMIA TYPE 3 (TYRO3)%PATHWHIZ%PW000121 Tyrosinemia Type 3 (TYRO3) 6898 3242 10056 2184 2805 2193 2954 5053 3081 259307 8565 REFSUM DISEASE%SMPDB%SMP0000451 Refsum Disease 5264 224 225 215 11001 26061 SIALURIA OR FRENCH TYPE SIALURIA%SMPDB%SMP0000216 Sialuria or French Type Sialuria 51005 5238 140838 55907 64841 10020 6675 3098 26503 3073 1118 10007 54187 80896 55577 2673 5973 SALLA DISEASE INFANTILE SIALIC ACID STORAGE DISEASE%SMPDB%SMP0000240 Salla Disease Infantile Sialic Acid Storage Disease 51005 5238 140838 55907 64841 10020 6675 3098 26503 3073 1118 10007 54187 80896 55577 2673 5973 PIROXICAM ACTION PATHWAY%SMPDB%SMP0000077 Piroxicam Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 IBANDRONATE ACTION PATHWAY%SMPDB%SMP0000079 Ibandronate Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 SIMVASTATIN ACTION PATHWAY%PATHWHIZ%PW000127 Simvastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 ACETYLSALICYLIC ACID ACTION PATHWAY%PATHWHIZ%PW000128 Acetylsalicylic Acid Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 ETODOLAC ACTION PATHWAY%PATHWHIZ%PW000129 Etodolac Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 KETOPROFEN ACTION PATHWAY%SMPDB%SMP0000085 Ketoprofen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 IBUPROFEN ACTION PATHWAY%SMPDB%SMP0000086 Ibuprofen Action Pathway 7363 4051 7364 113612 4056 10130 5740 64714 1579 1576 873 1573 4048 239 8529 51726 9356 240 242 6916 2876 2678 54600 246 247 5742 5743 127281 9601 11283 2053 1558 1557 1555 54575 54659 54658 5479 1559 9376 8644 9536 5730 1571 23753 10525 100137049 10961 3309 ROFECOXIB ACTION PATHWAY%SMPDB%SMP0000087 Rofecoxib Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 PRAVASTATIN ACTION PATHWAY%SMPDB%SMP0000089 Pravastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 ROSUVASTATIN ACTION PATHWAY%SMPDB%SMP0000092 Rosuvastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 DICLOFENAC ACTION PATHWAY%PATHWHIZ%PW000135 Diclofenac Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 SULINDAC ACTION PATHWAY%PATHWHIZ%PW000136 Sulindac Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 ALENDRONATE ACTION PATHWAY%PATHWHIZ%PW000137 Alendronate Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 CELECOXIB ACTION PATHWAY%SMPDB%SMP0000096 Celecoxib Action Pathway 125 1565 246 247 5742 5743 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 1576 873 1573 54575 4048 239 8529 1559 8644 9536 5730 1571 240 242 6916 2876 2678 124 100137049 KETOROLAC ACTION PATHWAY%SMPDB%SMP0000098 Ketorolac Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 PTERINE BIOSYNTHESIS%PATHWHIZ%PW000140 Pterine Biosynthesis 231 5805 2644 873 2643 5860 6697 1719 STEROIDOGENESIS%SMPDB%SMP0000130 Steroidogenesis 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 TYROSINE METABOLISM%SMPDB%SMP0000006 Tyrosine Metabolism 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 INOSITOL METABOLISM%SMPDB%SMP0000011 Inositol Metabolism 55586 3705 3706 3612 27124 253430 55697 114971 3631 55626 51477 3628 9562 5297 8678 30849 113026 5289 9896 64768 5290 200576 GLYCEROLIPID METABOLISM%SMPDB%SMP0000039 Glycerolipid Metabolism 4023 3990 132158 2819 218 10554 231 57678 2820 8611 8612 BILE ACID BIOSYNTHESIS%SMPDB%SMP0000035 Bile Acid Biosynthesis 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 GLYCOLYSIS%PATHWHIZ%PW000146 Glycolysis 5230 5223 5213 5224 2023 3099 130589 2821 226 2597 5313 669 6514 2538 SPHINGOLIPID METABOLISM%SMPDB%SMP0000034 Sphingolipid Metabolism 2581 123099 259230 10558 55331 410 2720 10825 2531 9517 8879 2629 2717 56848 9331 64781 8611 130367 9514 7357 7368 339221 125981 PROPANOATE METABOLISM%SMPDB%SMP0000016 Propanoate Metabolism 1629 1738 4329 31 5096 23417 34 38 18 92483 5095 593 594 26275 79611 84532 1892 84693 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW000150 Starch and Sucrose Metabolism 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 NICOTINATE AND NICOTINAMIDE METABOLISM%PATHWHIZ%PW000151 Nicotinate and Nicotinamide Metabolism 65220 22978 5167 4860 23530 23475 23057 55191 4837 54981 683 316 83594 10135 GLUCONEOGENESIS%PATHWHIZ%PW000152 Gluconeogenesis 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 LACTOSE DEGRADATION%SMPDB%SMP0000457 Lactose Degradation 478 6523 6514 480 481 482 483 486 476 3938 477 TRANSFER OF ACETYL GROUPS INTO MITOCHONDRIA%SMPDB%SMP0000466 Transfer of Acetyl Groups into Mitochondria 5160 5162 47 8402 4199 51660 5091 4190 OXIDATION OF BRANCHED-CHAIN FATTY ACIDS%SMPDB%SMP0000030 Oxidation of Branched-Chain Fatty Acids 215 788 217 1384 26061 5194 5195 2180 5264 225 1376 INOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0000462 Inositol Phosphate Metabolism 9562 8821 9677 64768 3705 3706 3612 27124 253430 11165 3631 51477 9807 3628 GLYCINE AND SERINE METABOLISM%SMPDB%SMP0000004 Glycine and Serine Metabolism 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 PORPHYRIN METABOLISM%SMPDB%SMP0000024 Porphyrin Metabolism 7389 5498 3145 1352 2990 7390 1371 3162 94033 210 55640 211 2235 1355 644 10720 GALACTOSE METABOLISM%SMPDB%SMP0000043 Galactose Metabolism 2683 5236 2582 2592 3098 2717 2538 7360 2548 231 3938 2720 PYRIMIDINE METABOLISM%PATHWHIZ%PW000160 Pyrimidine Metabolism 1635 1723 3704 1854 50484 54963 151531 1807 978 1806 51733 9615 10201 129607 6241 22978 7298 50808 1890 124583 7083 790 1503 BETA OXIDATION OF VERY LONG CHAIN FATTY ACIDS%PATHWHIZ%PW000161 Beta Oxidation of Very Long Chain Fatty Acids 215 788 1384 5194 5195 2180 92960 54677 225 1376 UREA CYCLE%PATHWHIZ%PW000162 Urea Cycle 6510 1373 383 2746 6509 27165 2875 445 435 8604 2806 10166 5009 TRYPTOPHAN METABOLISM%SMPDB%SMP0000063 Tryptophan Metabolism 10352 438 6999 847 8564 125061 7453 7166 15 8942 130013 11185 23498 1644 1543 51166 3620 217 RETINOL METABOLISM%SMPDB%SMP0000074 Retinol Metabolism 10901 124 54884 53630 10961 50700 3309 1549 1548 10170 8694 9249 9227 9601 8854 10130 64714 64816 1555 1577 1576 1553 216 1551 145226 54658 5479 8228 8608 51726 51109 6121 158833 1592 23753 10525 MITOCHONDRIAL ELECTRON TRANSPORT CHAIN%SMPDB%SMP0000355 Mitochondrial Electron Transport Chain 513 514 515 4512 506 54205 517 509 7384 4694 6389 291 6391 6390 6392 4508 498 2820 2542 2597 THREONINE AND 2-OXOBUTANOATE DEGRADATION%SMPDB%SMP0000452 Threonine and 2-Oxobutanoate Degradation 5096 594 4594 1629 1738 10993 5095 593 FATTY ACID BIOSYNTHESIS%SMPDB%SMP0000456 Fatty Acid Biosynthesis 2194 31 PHOSPHATIDYLINOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0000463 Phosphatidylinositol Phosphate Metabolism 23236 5293 200576 5728 56623 55697 55626 8867 5305 3635 1956 10423 5295 5286 5297 8821 8678 30849 5289 9896 2064 8394 TREHALOSE DEGRADATION%PATHWHIZ%PW000169 Trehalose Degradation 476 477 478 6523 6514 480 481 482 483 2645 486 11181 PLASMALOGEN SYNTHESIS%PATHWHIZ%PW000170 Plasmalogen Synthesis 8443 10390 8540 8611 10554 MITOCHONDRIAL BETA-OXIDATION OF SHORT CHAIN SATURATED FATTY ACIDS%PATHWHIZ%PW000171 Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids 33 35 10449 3028 38 79611 1892 3033 MITOCHONDRIAL BETA-OXIDATION OF MEDIUM CHAIN SATURATED FATTY ACIDS%PATHWHIZ%PW000172 Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids 116285 34 10449 788 1892 3033 3032 3030 MITOCHONDRIAL BETA-OXIDATION OF LONG CHAIN SATURATED FATTY ACIDS%SMPDB%SMP0000482 Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids 1374 3033 3032 3030 33 2180 10449 1376 788 1892 ACUTE INTERMITTENT PORPHYRIA%PATHWHIZ%PW000174 Acute Intermittent Porphyria 7389 5498 3145 1352 2990 7390 1371 3162 94033 210 55640 211 2235 1355 644 10720 PORPHYRIA VARIEGATA (PV)%SMPDB%SMP0000346 Porphyria Variegata (PV) 7389 5498 3145 1352 2990 7390 1371 3162 94033 210 55640 211 2235 1355 644 10720 CONGENITAL ERYTHROPOIETIC PORPHYRIA (CEP) OR GUNTHER DISEASE%SMPDB%SMP0000345 Congenital Erythropoietic Porphyria (CEP) or Gunther Disease 7389 5498 3145 1352 2990 7390 1371 3162 94033 210 55640 211 2235 1355 644 10720 ADRENAL HYPERPLASIA TYPE 3 OR CONGENITAL ADRENAL HYPERPLASIA DUE TO 21-HYDROXYLASE DEFICIENCY%SMPDB%SMP0000373 Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 CONGENITAL LIPOID ADRENAL HYPERPLASIA (CLAH) OR LIPOID CAH%SMPDB%SMP0000371 Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 ADRENAL HYPERPLASIA TYPE 5 OR CONGENITAL ADRENAL HYPERPLASIA DUE TO 17 ALPHA-HYDROXYLASE DEFICIENCY%SMPDB%SMP0000372 Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia Due to 17 alpha-Hydroxylase Deficiency 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 ALKAPTONURIA%PATHWHIZ%PW000180 Alkaptonuria 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 HAWKINSINURIA%PATHWHIZ%PW000181 Hawkinsinuria 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 TYROSINEMIA TYPE I%PATHWHIZ%PW000182 Tyrosinemia Type I 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 ARGININEMIA%PATHWHIZ%PW000183 Argininemia 6510 1373 383 2746 6509 27165 2875 445 435 8604 2806 10166 5009 ARGININOSUCCINIC ACIDURIA%PATHWHIZ%PW000184 Argininosuccinic Aciduria 6510 1373 383 2746 6509 27165 2875 445 435 8604 2806 10166 5009 CITRULLINEMIA TYPE I%PATHWHIZ%PW000185 Citrullinemia Type I 6510 1373 383 2746 6509 27165 2875 445 435 8604 2806 10166 5009 ORNITHINE TRANSCARBAMYLASE DEFICIENCY (OTC DEFICIENCY)%SMPDB%SMP0000205 Ornithine Transcarbamylase Deficiency (OTC Deficiency) 6510 1373 383 2746 6509 27165 2875 445 435 8604 2806 10166 5009 BETA-UREIDOPROPIONASE DEFICIENCY%PATHWHIZ%PW000187 beta-Ureidopropionase Deficiency 1635 1723 3704 1854 50484 54963 151531 1807 978 1806 51733 9615 10201 129607 6241 22978 7298 50808 1890 124583 7083 790 1503 UMP SYNTHASE DEFICIENCY (OROTIC ACIDURIA)%SMPDB%SMP0000219 UMP Synthase Deficiency (Orotic Aciduria) 1635 1723 3704 1854 50484 54963 151531 1807 978 1806 51733 9615 10201 129607 6241 22978 7298 50808 1890 124583 7083 790 1503 DIHYDROPYRIMIDINASE DEFICIENCY%SMPDB%SMP0000178 Dihydropyrimidinase Deficiency 1635 1723 3704 1854 50484 54963 151531 1807 978 1806 51733 9615 10201 129607 6241 22978 7298 50808 1890 124583 7083 790 1503 MNGIE (MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOPATHY)%PATHWHIZ%PW000190 MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) 1635 1723 3704 1854 50484 54963 151531 1807 978 1806 51733 9615 10201 129607 6241 22978 7298 50808 1890 124583 7083 790 1503 CARBAMOYL PHOSPHATE SYNTHETASE DEFICIENCY%SMPDB%SMP0000002 Carbamoyl Phosphate Synthetase Deficiency 6510 1373 383 2746 6509 27165 2875 445 435 8604 2806 10166 5009 CONGENITAL BILE ACID SYNTHESIS DEFECT TYPE II%PATHWHIZ%PW000192 Congenital Bile Acid Synthesis Defect Type II 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 CONGENITAL BILE ACID SYNTHESIS DEFECT TYPE III%PATHWHIZ%PW000193 Congenital Bile Acid Synthesis Defect Type III 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 FAMILIAL HYPERCHOLANEMIA (FHCA)%PATHWHIZ%PW000194 Familial Hypercholanemia (FHCA) 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 ZELLWEGER SYNDROME%PATHWHIZ%PW000195 Zellweger Syndrome 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 CEREBROTENDINOUS XANTHOMATOSIS (CTX)%PATHWHIZ%PW000196 Cerebrotendinous Xanthomatosis (CTX) 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 DIMETHYLGLYCINE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000242 Dimethylglycine Dehydrogenase Deficiency 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 DIHYDROPYRIMIDINE DEHYDROGENASE DEFICIENCY (DHPD)%SMPDB%SMP0000179 Dihydropyrimidine Dehydrogenase Deficiency (DHPD) 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 SARCOSINEMIA%SMPDB%SMP0000244 Sarcosinemia 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 GALACTOSEMIA%PATHWHIZ%PW000200 Galactosemia 2683 5236 2582 2592 3098 2717 2538 7360 2548 231 3938 2720 GAUCHER DISEASE%PATHWHIZ%PW000201 Gaucher Disease 2581 123099 259230 10558 55331 410 2720 10825 2531 9517 8879 2629 2717 56848 9331 64781 8611 130367 9514 7357 7368 339221 125981 GLOBOID CELL LEUKODYSTROPHY%PATHWHIZ%PW000202 Globoid Cell Leukodystrophy 2581 123099 259230 10558 55331 410 2720 10825 2531 9517 8879 2629 2717 56848 9331 64781 8611 130367 9514 7357 7368 339221 125981 METACHROMATIC LEUKODYSTROPHY (MLD)%SMPDB%SMP0000347 Metachromatic Leukodystrophy (MLD) 2581 123099 259230 10558 55331 410 2720 10825 2531 9517 8879 2629 2717 56848 9331 64781 8611 130367 9514 7357 7368 339221 125981 GLYCEROL KINASE DEFICIENCY%SMPDB%SMP0000187 Glycerol Kinase Deficiency 4023 3990 132158 2819 218 10554 231 57678 2820 8611 8612 GLYCOGEN STORAGE DISEASE TYPE 1A (GSD1A) OR VON GIERKE DISEASE%SMPDB%SMP0000374 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 LACTOSE INTOLERANCE%PATHWHIZ%PW000206 Lactose Intolerance 478 6523 6514 480 481 482 483 486 476 3938 477 MALONIC ACIDURIA%SMPDB%SMP0000198 Malonic Aciduria 1629 1738 4329 31 5096 23417 34 38 18 92483 5095 593 594 26275 79611 84532 1892 84693 METHYLMALONIC ACIDURIA DUE TO COBALAMIN-RELATED DISORDERS%PATHWHIZ%PW000208 Methylmalonic Aciduria Due to Cobalamin-Related Disorders 1629 1738 4329 31 5096 23417 34 38 18 92483 5095 593 594 26275 79611 84532 1892 84693 NON-KETOTIC HYPERGLYCINEMIA%PATHWHIZ%PW000209 Non-Ketotic Hyperglycinemia 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 VITAMIN A DEFICIENCY%SMPDB%SMP0000336 Vitamin A Deficiency 10901 124 54884 53630 10961 50700 3309 1549 1548 10170 8694 9249 9227 9601 8854 10130 64714 64816 1555 1577 1576 1553 216 1551 145226 54658 5479 8228 8608 51726 51109 6121 158833 1592 23753 10525 HEREDITARY COPROPORPHYRIA (HCP)%SMPDB%SMP0000342 Hereditary Coproporphyria (HCP) 7389 5498 3145 1352 2990 7390 1371 3162 94033 210 55640 211 2235 1355 644 10720 2-HYDROXYGLUTRIC ACIDURIA (D AND L FORM)%SMPDB%SMP0000136 2-Hydroxyglutric Aciduria (D and L Form) 2730 124454 55577 2673 8659 8833 2806 2729 2937 2936 5859 7915 5471 64841 18 1373 2571 790 2746 27165 2875 2752 3-METHYLGLUTACONIC ACIDURIA TYPE IV%SMPDB%SMP0000141 3-Methylglutaconic Aciduria Type IV 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 TAY-SACHS DISEASE%PATHWHIZ%PW000215 Tay-Sachs Disease 51005 5238 140838 55907 64841 10020 6675 3098 26503 3073 1118 10007 54187 80896 55577 2673 5973 GLUCOSE TRANSPORTER DEFECT (SGLT2)%SMPDB%SMP0000184 Glucose Transporter Defect (SGLT2) 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 HARTNUP DISORDER%SMPDB%SMP0000189 Hartnup Disorder 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 IMINOGLYCINURIA%PATHWHIZ%PW000219 Iminoglycinuria 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 LYSINURIC PROTEIN INTOLERANCE%SMPDB%SMP0000197 Lysinuric Protein Intolerance 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 HYPERCHOLESTEROLEMIA%PATHWHIZ%PW000221 Hypercholesterolemia 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 NEURON FUNCTION%SMPDB%SMP0000224 Neuron Function 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 BENAZEPRIL ACTION PATHWAY%SMPDB%SMP0000145 Benazepril Action Pathway 5972 183 1636 CAPTOPRIL ACTION PATHWAY%SMPDB%SMP0000146 Captopril Action Pathway 5972 183 1636 CILAZAPRIL ACTION PATHWAY%SMPDB%SMP0000147 Cilazapril Action Pathway 5972 183 1636 ENALAPRIL ACTION PATHWAY%SMPDB%SMP0000148 Enalapril Action Pathway 5972 183 1636 FOSINOPRIL ACTION PATHWAY%PATHWHIZ%PW000227 Fosinopril Action Pathway 5972 183 1636 LISINOPRIL ACTION PATHWAY%PATHWHIZ%PW000228 Lisinopril Action Pathway 5972 183 1636 MOEXIPRIL ACTION PATHWAY%SMPDB%SMP0000151 Moexipril Action Pathway 5972 183 1636 PERINDOPRIL ACTION PATHWAY%SMPDB%SMP0000152 Perindopril Action Pathway 5972 183 1636 QUINAPRIL ACTION PATHWAY%SMPDB%SMP0000153 Quinapril Action Pathway 5972 183 1636 RAMIPRIL ACTION PATHWAY%SMPDB%SMP0000154 Ramipril Action Pathway 5972 183 1636 RESCINNAMINE ACTION PATHWAY%SMPDB%SMP0000155 Rescinnamine Action Pathway 5972 183 1636 SPIRAPRIL ACTION PATHWAY%SMPDB%SMP0000156 Spirapril Action Pathway 5972 183 1636 TRANDOLAPRIL ACTION PATHWAY%SMPDB%SMP0000157 Trandolapril Action Pathway 5972 183 1636 BEVACIZUMAB ACTION PATHWAY%SMPDB%SMP0000420 Bevacizumab Action Pathway 7422 3791 2321 VATALANIB ACTION PATHWAY%SMPDB%SMP0000421 Vatalanib Action Pathway 3791 IRINOTECAN ACTION PATHWAY%PATHWHIZ%PW000238 Irinotecan Action Pathway 64714 10525 1577 54600 1576 1244 54575 8824 9429 54658 5479 10961 3309 51726 10599 5243 9601 4363 10130 1066 590 7150 23753 PACLITAXEL ACTION PATHWAY%PATHWHIZ%PW000239 Paclitaxel Action Pathway 81027 5243 4363 1244 28234 9429 10376 DOCETAXEL ACTION PATHWAY%PATHWHIZ%PW000240 Docetaxel Action Pathway 81027 5243 4363 1244 28234 9429 10376 VINBLASTINE ACTION PATHWAY%SMPDB%SMP0000436 Vinblastine Action Pathway 7157 1244 89845 8714 10928 10376 81027 5243 1576 4363 1026 VINCRISTINE ACTION PATHWAY%SMPDB%SMP0000437 Vincristine Action Pathway 89845 8714 10928 10376 81027 5243 4363 1026 7157 1244 VINDESINE ACTION PATHWAY%SMPDB%SMP0000438 Vindesine Action Pathway 89845 8714 10928 10376 81027 5243 4363 1026 7157 1244 VINORELBINE ACTION PATHWAY%SMPDB%SMP0000439 Vinorelbine Action Pathway 7157 1244 89845 8714 10928 10376 81027 5243 1576 4363 1026 ETOPOSIDE ACTION PATHWAY%SMPDB%SMP0000442 Etoposide Action Pathway 5742 54658 5479 5743 10961 3309 51726 7153 7155 5243 9601 4353 10130 23753 64714 10525 1577 1576 8714 TENIPOSIDE ACTION PATHWAY%SMPDB%SMP0000443 Teniposide Action Pathway 7153 1577 1576 4353 GEMCITABINE ACTION PATHWAY%SMPDB%SMP0000446 Gemcitabine Action Pathway 6241 6240 51727 64078 7298 2030 9154 1503 1635 1633 50484 4830 30833 CYCLOPHOSPHAMIDE ACTION PATHWAY%PATHWHIZ%PW000248 Cyclophosphamide Action Pathway 1548 1559 2944 1558 1557 1555 1576 216 218 IFOSFAMIDE ACTION PATHWAY%PATHWHIZ%PW000249 Ifosfamide Action Pathway 1558 1555 1577 1576 216 218 1548 1559 TAMOXIFEN ACTION PATHWAY%SMPDB%SMP0000471 Tamoxifen Action Pathway 1565 54575 2099 54657 2328 6817 2326 1555 1577 1576 ERLOTINIB ACTION PATHWAY%PATHWHIZ%PW000251 Erlotinib Action Pathway 5243 9429 1956 GEFITINIB ACTION PATHWAY%SMPDB%SMP0000473 Gefitinib Action Pathway 1956 CETUXIMAB ACTION PATHWAY%SMPDB%SMP0000474 Cetuximab Action Pathway 1956 PANITUMUMAB ACTION PATHWAY%SMPDB%SMP0000475 Panitumumab Action Pathway 1956 TRASTUZUMAB ACTION PATHWAY%SMPDB%SMP0000476 Trastuzumab Action Pathway 1956 CAPECITABINE ACTION PATHWAY%PATHWHIZ%PW000256 Capecitabine Action Pathway 7298 1066 1890 978 9154 FLUOROURACIL ACTION PATHWAY%SMPDB%SMP0000470 Fluorouracil Action Pathway 7298 SUPROFEN ACTION PATHWAY%SMPDB%SMP0000101 Suprofen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 BROMFENAC ACTION PATHWAY%SMPDB%SMP0000102 Bromfenac Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 INDOMETHACIN ACTION PATHWAY%PATHWHIZ%PW000260 Indomethacin Action Pathway 4051 127281 113612 5320 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 MEFENAMIC ACID ACTION PATHWAY%PATHWHIZ%PW000261 Mefenamic Acid Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 OXAPROZIN ACTION PATHWAY%PATHWHIZ%PW000262 Oxaprozin Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 NABUMETONE ACTION PATHWAY%SMPDB%SMP0000114 Nabumetone Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 NAPROXEN ACTION PATHWAY%SMPDB%SMP0000120 Naproxen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 DIFLUNISAL ACTION PATHWAY%SMPDB%SMP0000289 Diflunisal Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 AZATHIOPRINE ACTION PATHWAY%SMPDB%SMP0000427 Azathioprine Action Pathway 10057 318 957 9615 10257 1716 5879 6241 6240 5471 5198 7498 4860 3177 377841 9153 3251 7172 7295 2977 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 64078 5144 11164 270 2030 471 132 353 3614 2987 2766 158 159 2983 316 MERCAPTOPURINE ACTION PATHWAY%PATHWHIZ%PW000267 Mercaptopurine Action Pathway 10057 318 957 9615 10257 1716 5879 6241 6240 5471 5198 7498 4860 3177 377841 9153 3251 7172 7295 2977 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 64078 5144 11164 270 2030 471 132 353 3614 2987 2766 158 159 2983 316 METHOTREXATE ACTION PATHWAY%SMPDB%SMP0000432 Methotrexate Action Pathway 1719 4522 8836 4524 10840 10841 10797 10588 25902 2356 113235 123263 LOVASTATIN ACTION PATHWAY%SMPDB%SMP0000099 Lovastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 ZOLEDRONATE ACTION PATHWAY%PATHWHIZ%PW000270 Zoledronate Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 CERIVASTATIN ACTION PATHWAY%PATHWHIZ%PW000271 Cerivastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 RISEDRONATE ACTION PATHWAY%PATHWHIZ%PW000272 Risedronate Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 PAMIDRONATE ACTION PATHWAY%PATHWHIZ%PW000273 Pamidronate Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 FLUVASTATIN ACTION PATHWAY%PATHWHIZ%PW000274 Fluvastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 ATORVASTATIN ACTION PATHWAY%SMPDB%SMP0000131 Atorvastatin Action Pathway 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 MELOXICAM ACTION PATHWAY%SMPDB%SMP0000106 Meloxicam Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 VALDECOXIB ACTION PATHWAY%SMPDB%SMP0000116 Valdecoxib Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 CANDESARTAN ACTION PATHWAY%SMPDB%SMP0000158 Candesartan Action Pathway 54331 2776 5972 2782 183 185 1636 EPROSARTAN ACTION PATHWAY%PATHWHIZ%PW000279 Eprosartan Action Pathway 54331 2776 5972 2782 183 185 1636 FORASARTAN ACTION PATHWAY%PATHWHIZ%PW000280 Forasartan Action Pathway 5972 183 185 1636 IRBESARTAN ACTION PATHWAY%PATHWHIZ%PW000281 Irbesartan Action Pathway 54331 2776 5972 2782 183 185 1636 LOSARTAN ACTION PATHWAY%PATHWHIZ%PW000282 Losartan Action Pathway 54331 2776 5972 2782 183 185 1636 OLMESARTAN ACTION PATHWAY%SMPDB%SMP0000163 Olmesartan Action Pathway 54331 2776 5972 2782 183 185 1636 TELMISARTAN ACTION PATHWAY%PATHWHIZ%PW000284 Telmisartan Action Pathway 54331 2776 5972 2782 183 185 1636 VALSARTAN ACTION PATHWAY%SMPDB%SMP0000165 Valsartan Action Pathway 54331 2776 5972 2782 183 185 1636 CLOPIDOGREL ACTION PATHWAY%PATHWHIZ%PW000286 Clopidogrel Action Pathway 64805 1559 1557 1544 1555 1577 5243 1576 5444 TICLOPIDINE ACTION PATHWAY%SMPDB%SMP0000261 Ticlopidine Action Pathway 64805 CLOMOCYCLINE ACTION PATHWAY%SMPDB%SMP0000262 Clomocycline Action Pathway 947096 CILOSTAZOL ACTION PATHWAY%SMPDB%SMP0000263 Cilostazol Action Pathway 1557 1577 1576 5144 DIPYRIDAMOLE (ANTIPLATELET) ACTION PATHWAY%SMPDB%SMP0000264 Dipyridamole (Antiplatelet) Action Pathway 5144 ABCIXIMAB ACTION PATHWAY%SMPDB%SMP0000265 Abciximab Action Pathway 3690 3674 EPTIFIBATIDE ACTION PATHWAY%PATHWHIZ%PW000292 Eptifibatide Action Pathway 3690 3674 TIROFIBAN ACTION PATHWAY%PATHWHIZ%PW000293 Tirofiban Action Pathway 3690 3674 ENOXAPARIN ACTION PATHWAY%SMPDB%SMP0000272 Enoxaparin Action Pathway 2677 2159 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 462 FONDAPARINUX ACTION PATHWAY%SMPDB%SMP0000273 Fondaparinux Action Pathway 2677 2159 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 462 HEPARIN ACTION PATHWAY%SMPDB%SMP0000274 Heparin Action Pathway 2677 2159 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 462 ARDEPARIN ACTION PATHWAY%SMPDB%SMP0000275 Ardeparin Action Pathway 2677 2159 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 462 ARGATROBAN ACTION PATHWAY%SMPDB%SMP0000276 Argatroban Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 BIVALIRUDIN ACTION PATHWAY%SMPDB%SMP0000277 Bivalirudin Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 LEPIRUDIN ACTION PATHWAY%SMPDB%SMP0000278 Lepirudin Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 XIMELAGATRAN ACTION PATHWAY%SMPDB%SMP0000279 Ximelagatran Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 ALTEPLASE ACTION PATHWAY%PATHWHIZ%PW000302 Alteplase Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 ANISTREPLASE ACTION PATHWAY%PATHWHIZ%PW000303 Anistreplase Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 STREPTOKINASE ACTION PATHWAY%PATHWHIZ%PW000304 Streptokinase Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 TENECTEPLASE ACTION PATHWAY%SMPDB%SMP0000283 Tenecteplase Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 UROKINASE ACTION PATHWAY%SMPDB%SMP0000284 Urokinase Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 RETEPLASE ACTION PATHWAY%SMPDB%SMP0000285 Reteplase Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 AMINOCAPROIC ACID ACTION PATHWAY%PATHWHIZ%PW000308 Aminocaproic Acid Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 TRANEXAMIC ACID ACTION PATHWAY%PATHWHIZ%PW000309 Tranexamic Acid Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 APROTININ ACTION PATHWAY%SMPDB%SMP0000288 Aprotinin Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 WARFARIN ACTION PATHWAY%SMPDB%SMP0000268 Warfarin Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 ACENOCOUMAROL ACTION PATHWAY%PATHWHIZ%PW000312 Acenocoumarol Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 DICUMAROL ACTION PATHWAY%PATHWHIZ%PW000313 Dicumarol Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 PHENPROCOUMON ACTION PATHWAY%PATHWHIZ%PW000314 Phenprocoumon Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 ESOMEPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000315 Esomeprazole Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 OMEPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000316 Omeprazole Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 LANSOPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000317 Lansoprazole Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 PANTOPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000318 Pantoprazole Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 RABEPRAZOLE ACTION PATHWAY%PATHWHIZ%PW000319 Rabeprazole Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 RANITIDINE ACTION PATHWAY%SMPDB%SMP0000230 Ranitidine Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 FAMOTIDINE ACTION PATHWAY%SMPDB%SMP0000231 Famotidine Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 CIMETIDINE ACTION PATHWAY%SMPDB%SMP0000232 Cimetidine Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 NIZATIDINE ACTION PATHWAY%SMPDB%SMP0000233 Nizatidine Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 PIRENZEPINE ACTION PATHWAY%SMPDB%SMP0000246 Pirenzepine Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 CHLOROTHIAZIDE ACTION PATHWAY%SMPDB%SMP0000078 Chlorothiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 POLYTHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000326 Polythiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 METHYCLOTHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000327 Methyclothiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 BUMETANIDE ACTION PATHWAY%SMPDB%SMP0000088 Bumetanide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 BENDROFLUMETHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000329 Bendroflumethiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 QUINETHAZONE ACTION PATHWAY%SMPDB%SMP0000091 Quinethazone Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 ETHACRYNIC ACID ACTION PATHWAY%SMPDB%SMP0000097 Ethacrynic Acid Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 HYDROCHLOROTHIAZIDE ACTION PATHWAY%SMPDB%SMP0000100 Hydrochlorothiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 CYCLOTHIAZIDE ACTION PATHWAY%SMPDB%SMP0000103 Cyclothiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 METOLAZONE ACTION PATHWAY%SMPDB%SMP0000105 Metolazone Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 HYDROFLUMETHIAZIDE ACTION PATHWAY%PATHWHIZ%PW000335 Hydroflumethiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 INDAPAMIDE ACTION PATHWAY%SMPDB%SMP0000110 Indapamide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 FUROSEMIDE ACTION PATHWAY%PATHWHIZ%PW000337 Furosemide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 TORSEMIDE ACTION PATHWAY%PATHWHIZ%PW000338 Torsemide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 TRICHLORMETHIAZIDE ACTION PATHWAY%SMPDB%SMP0000121 Trichlormethiazide Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 CHLORTHALIDONE ACTION PATHWAY%SMPDB%SMP0000122 Chlorthalidone Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 TRIAMTERENE ACTION PATHWAY%SMPDB%SMP0000132 Triamterene Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 AMILORIDE ACTION PATHWAY%SMPDB%SMP0000133 Amiloride Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 SPIRONOLACTONE ACTION PATHWAY%SMPDB%SMP0000134 Spironolactone Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 EPLERENONE ACTION PATHWAY%SMPDB%SMP0000135 Eplerenone Action Pathway 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 AZITHROMYCIN ACTION PATHWAY%PATHWHIZ%PW000345 Azithromycin Action Pathway 947096 CLARITHROMYCIN ACTION PATHWAY%SMPDB%SMP0000248 Clarithromycin Action Pathway 947096 CLINDAMYCIN ACTION PATHWAY%PATHWHIZ%PW000347 Clindamycin Action Pathway 947096 ERYTHROMYCIN ACTION PATHWAY%SMPDB%SMP0000250 Erythromycin Action Pathway 947096 ROXITHROMYCIN ACTION PATHWAY%SMPDB%SMP0000251 Roxithromycin Action Pathway 947096 TELITHROMYCIN ACTION PATHWAY%PATHWHIZ%PW000350 Telithromycin Action Pathway 947096 AMIKACIN ACTION PATHWAY%SMPDB%SMP0000253 Amikacin Action Pathway 947096 GENTAMICIN ACTION PATHWAY%SMPDB%SMP0000254 Gentamicin Action Pathway 947096 KANAMYCIN ACTION PATHWAY%SMPDB%SMP0000255 Kanamycin Action Pathway 947096 NEOMYCIN ACTION PATHWAY%SMPDB%SMP0000256 Neomycin Action Pathway 947096 NETILMICIN ACTION PATHWAY%SMPDB%SMP0000257 Netilmicin Action Pathway 947096 SPECTINOMYCIN ACTION PATHWAY%PATHWHIZ%PW000356 Spectinomycin Action Pathway 947096 STREPTOMYCIN ACTION PATHWAY%SMPDB%SMP0000259 Streptomycin Action Pathway 947096 DEMECLOCYCLINE ACTION PATHWAY%PATHWHIZ%PW000358 Demeclocycline Action Pathway 947096 DOXYCYCLINE ACTION PATHWAY%PATHWHIZ%PW000359 Doxycycline Action Pathway 947096 MINOCYCLINE ACTION PATHWAY%PATHWHIZ%PW000360 Minocycline Action Pathway 947096 OXYTETRACYCLINE ACTION PATHWAY%PATHWHIZ%PW000361 Oxytetracycline Action Pathway 947096 TETRACYCLINE ACTION PATHWAY%SMPDB%SMP0000294 Tetracycline Action Pathway 947096 LYMECYCLINE ACTION PATHWAY%SMPDB%SMP0000295 Lymecycline Action Pathway 947096 ACEBUTOLOL ACTION PATHWAY%SMPDB%SMP0000296 Acebutolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 ALPRENOLOL ACTION PATHWAY%SMPDB%SMP0000297 Alprenolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 ATENOLOL ACTION PATHWAY%SMPDB%SMP0000298 Atenolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 BETAXOLOL ACTION PATHWAY%SMPDB%SMP0000299 Betaxolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 BISOPROLOL ACTION PATHWAY%SMPDB%SMP0000300 Bisoprolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 ESMOLOL ACTION PATHWAY%SMPDB%SMP0000301 Esmolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 METOPROLOL ACTION PATHWAY%PATHWHIZ%PW000370 Metoprolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 NADOLOL ACTION PATHWAY%PATHWHIZ%PW000371 Nadolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 OXPRENOLOL ACTION PATHWAY%PATHWHIZ%PW000372 Oxprenolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 PENBUTOLOL ACTION PATHWAY%SMPDB%SMP0000305 Penbutolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 PINDOLOL ACTION PATHWAY%PATHWHIZ%PW000374 Pindolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 PROPRANOLOL ACTION PATHWAY%SMPDB%SMP0000307 Propranolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 QUINIDINE ACTION PATHWAY%SMPDB%SMP0000323 Quinidine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 PROCAINAMIDE (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000377 Procainamide (Antiarrhythmic) Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 DISOPYRAMIDE ACTION PATHWAY%SMPDB%SMP0000325 Disopyramide Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 FOSPHENYTOIN (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000379 Fosphenytoin (Antiarrhythmic) Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 PHENYTOIN (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000380 Phenytoin (Antiarrhythmic) Action Pathway 8912 5566 3784 8913 3741 1728 10961 3309 7169 7168 3760 10130 30819 3761 64714 153 3759 476 1576 477 478 6546 3752 3753 1739 3757 51726 5350 10060 9992 6641 6640 480 481 482 483 144245 486 1544 54600 488 3762 10021 3764 6833 3767 6331 9601 2052 1557 54578 1312 775 6645 54658 5479 3775 54657 1559 6262 9254 5573 1571 23753 1129 10525 782 LIDOCAINE (ANTIARRHYTHMIC) ACTION PATHWAY%PATHWHIZ%PW000381 Lidocaine (Antiarrhythmic) Action Pathway 3752 3775 3753 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 1544 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 1576 477 478 775 6546 6645 MEXILETINE ACTION PATHWAY%PATHWHIZ%PW000382 Mexiletine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 TOCAINIDE ACTION PATHWAY%SMPDB%SMP0000330 Tocainide Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 FLECAINIDE ACTION PATHWAY%SMPDB%SMP0000331 Flecainide Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 IBUTILIDE ACTION PATHWAY%SMPDB%SMP0000332 Ibutilide Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 DILTIAZEM ACTION PATHWAY%SMPDB%SMP0000359 Diltiazem Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 NEBIVOLOL ACTION PATHWAY%SMPDB%SMP0000366 Nebivolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 CARVEDILOL ACTION PATHWAY%SMPDB%SMP0000367 Carvedilol Action Pathway 3753 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 148 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 LABETALOL ACTION PATHWAY%PATHWHIZ%PW000389 Labetalol Action Pathway 3753 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 148 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 VERAPAMIL ACTION PATHWAY%SMPDB%SMP0000375 Verapamil Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 AMLODIPINE ACTION PATHWAY%PATHWHIZ%PW000391 Amlodipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 FELODIPINE ACTION PATHWAY%PATHWHIZ%PW000392 Felodipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 ISRADIPINE ACTION PATHWAY%PATHWHIZ%PW000393 Isradipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 NIFEDIPINE ACTION PATHWAY%PATHWHIZ%PW000394 Nifedipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 NIMODIPINE ACTION PATHWAY%PATHWHIZ%PW000395 Nimodipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 NISOLDIPINE ACTION PATHWAY%PATHWHIZ%PW000396 Nisoldipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 NITRENDIPINE ACTION PATHWAY%SMPDB%SMP0000382 Nitrendipine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 BENZOCAINE ACTION PATHWAY%SMPDB%SMP0000392 Benzocaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 BUPIVACAINE ACTION PATHWAY%SMPDB%SMP0000393 Bupivacaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 CHLOROPROCAINE ACTION PATHWAY%SMPDB%SMP0000394 Chloroprocaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 COCAINE ACTION PATHWAY%SMPDB%SMP0000395 Cocaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 DIBUCAINE ACTION PATHWAY%SMPDB%SMP0000396 Dibucaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 LEVOBUPIVACAINE ACTION PATHWAY%PATHWHIZ%PW000403 Levobupivacaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 LIDOCAINE (LOCAL ANAESTHETIC) ACTION PATHWAY%SMPDB%SMP0000398 Lidocaine (Local Anaesthetic) Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 1576 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 1544 116443 148 5126 6336 MEPIVACAINE ACTION PATHWAY%PATHWHIZ%PW000405 Mepivacaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 OXYBUPROCAINE ACTION PATHWAY%SMPDB%SMP0000400 Oxybuprocaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 PRILOCAINE ACTION PATHWAY%PATHWHIZ%PW000407 Prilocaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 PROCAINE ACTION PATHWAY%PATHWHIZ%PW000408 Procaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 PROPARACAINE ACTION PATHWAY%PATHWHIZ%PW000409 Proparacaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 ROPIVACAINE ACTION PATHWAY%PATHWHIZ%PW000410 Ropivacaine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 CODEINE ACTION PATHWAY%PATHWHIZ%PW000411 Codeine Action Pathway 5126 6336 7364 6531 6530 5443 30819 6532 1141 773 476 1137 1576 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 1565 116443 148 MORPHINE ACTION PATHWAY%PATHWHIZ%PW000412 Morphine Action Pathway 54576 54659 3751 54658 5479 4988 2903 2902 51726 1812 9254 6324 3350 480 23753 481 482 483 10525 782 486 116443 148 5126 6336 10961 3309 7363 7364 9601 6531 6530 7366 5443 10130 30819 6532 1141 64714 773 476 1137 477 478 METHADONE ACTION PATHWAY%PATHWHIZ%PW000414 Methadone Action Pathway 483 782 486 1565 116443 148 5126 6336 6531 6530 5443 30819 6532 1141 1558 1557 773 476 1555 1137 1576 477 478 1551 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 OXYCODONE ACTION PATHWAY%SMPDB%SMP0000409 Oxycodone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 HYDROMORPHONE ACTION PATHWAY%PATHWHIZ%PW000416 Hydromorphone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 HYDROCODONE ACTION PATHWAY%SMPDB%SMP0000411 Hydrocodone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 OXYMORPHONE ACTION PATHWAY%PATHWHIZ%PW000418 Oxymorphone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 ALFENTANIL ACTION PATHWAY%PATHWHIZ%PW000419 Alfentanil Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 CARFENTANIL ACTION PATHWAY%SMPDB%SMP0000414 Carfentanil Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 FENTANYL ACTION PATHWAY%PATHWHIZ%PW000421 Fentanyl Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 REMIFENTANIL ACTION PATHWAY%PATHWHIZ%PW000422 Remifentanil Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 SUFENTANIL ACTION PATHWAY%PATHWHIZ%PW000423 Sufentanil Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 IMIPRAMINE ACTION PATHWAY%SMPDB%SMP0000422 Imipramine Action Pathway 116443 148 5126 6336 6531 6530 5443 30819 6532 1141 1557 773 476 1137 1576 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 1544 1565 DESIPRAMINE ACTION PATHWAY%PATHWHIZ%PW000425 Desipramine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 1565 116443 148 5126 6336 CITALOPRAM ACTION PATHWAY%PATHWHIZ%PW000426 Citalopram Action Pathway 483 782 486 1565 116443 148 5126 6336 6531 6530 5443 30819 6532 1141 1557 773 476 1137 477 478 1551 316 3751 4128 4129 4988 2903 2902 1812 9254 6324 3350 480 481 482 ESCITALOPRAM ACTION PATHWAY%PATHWHIZ%PW000427 Escitalopram Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 FLUOXETINE ACTION PATHWAY%PATHWHIZ%PW000428 Fluoxetine Action Pathway 486 1565 116443 148 5126 6336 6531 6530 5443 30819 6532 1141 1557 773 476 1577 1137 1576 477 478 3751 4988 2903 2902 1559 1812 9254 6324 3350 480 481 482 483 782 THIOGUANINE ACTION PATHWAY%PATHWHIZ%PW000429 Thioguanine Action Pathway 10057 318 957 9615 10257 1716 5879 6241 6240 5471 5198 7498 4860 3177 377841 9153 3251 7172 7295 2977 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 64078 5144 11164 270 2030 471 132 353 3614 2987 2766 158 159 2983 316 NICOTINE ACTION PATHWAY%SMPDB%SMP0000431 Nicotine Action Pathway 482 483 782 486 54600 116443 148 5126 6336 1548 6531 6530 5443 30819 6532 1141 2328 773 476 1555 1137 1136 477 478 316 3751 54657 4988 2903 2902 1812 9254 6324 3350 480 481 DISULFIRAM ACTION PATHWAY%PATHWHIZ%PW000431 Disulfiram Action Pathway 1644 124 1621 125 1312 84532 217 55902 218 219 847 4128 2805 1638 4282 3081 7299 26 1571 23498 2184 5409 2954 NATEGLINIDE ACTION PATHWAY%SMPDB%SMP0000453 Nateglinide Action Pathway 782 9254 773 3630 6514 6833 REPAGLINIDE ACTION PATHWAY%SMPDB%SMP0000454 Repaglinide Action Pathway 782 9254 773 3630 6514 6833 GLIBENCLAMIDE ACTION PATHWAY%SMPDB%SMP0000460 Glibenclamide Action Pathway 782 9254 773 3630 6514 6833 GLICLAZIDE ACTION PATHWAY%SMPDB%SMP0000461 Gliclazide Action Pathway 782 9254 773 3630 6514 6833 PREDNISONE ACTION PATHWAY%SMPDB%SMP0000440 Prednisone Action Pathway 1576 PREDNISOLONE ACTION PATHWAY%SMPDB%SMP0000441 Prednisolone Action Pathway 2908 3320 DOPAMINE ACTIVATION OF NEUROLOGICAL REWARD SYSTEM%PATHWHIZ%PW000440 Dopamine Activation of Neurological Reward System 2778 5567 108 1812 EXCITATORY NEURAL SIGNALLING THROUGH 5-HTR 4 AND SEROTONIN%PATHWHIZ%PW000441 Excitatory Neural Signalling Through 5-HTR 4 and Serotonin 2778 5499 1385 2782 5567 2792 837856 3360 CORTICOTROPIN ACTIVATION OF CORTISOL PRODUCTION%SMPDB%SMP0000310 Corticotropin Activation of Cortisol Production 2778 5443 2782 4158 5567 2792 EXCITATORY NEURAL SIGNALLING THROUGH 5-HTR 7 AND SEROTONIN%SMPDB%SMP0000311 Excitatory Neural Signalling Through 5-HTR 7 and Serotonin 2778 5499 1385 2782 5567 2792 3363 837856 EXCITATORY NEURAL SIGNALLING THROUGH 5-HTR 6 AND SEROTONIN%SMPDB%SMP0000312 Excitatory Neural Signalling Through 5-HTR 6 and Serotonin 2778 5499 1385 2782 5567 2792 837856 3362 INTRACELLULAR SIGNALLING THROUGH ADENOSINE RECEPTOR A2A AND ADENOSINE%SMPDB%SMP0000320 Intracellular Signalling Through Adenosine Receptor A2a and Adenosine 5906 1147 1386 5567 207 4214 5600 4216 5605 3725 4790 4791 4792 8874 1385 3265 2792 6195 572 673 135 2002 5599 998 10411 50855 5594 5058 2782 3551 5290 5170 9693 5590 5608 2778 5609 INTRACELLULAR SIGNALLING THROUGH ADENOSINE RECEPTOR A2B AND ADENOSINE%SMPDB%SMP0000321 Intracellular Signalling Through Adenosine Receptor A2b and Adenosine 5609 5906 1147 1386 5567 207 108 4214 5600 4216 5605 3725 4790 4791 4792 8874 1385 3265 2792 6195 572 673 136 2002 5599 998 10411 50855 5594 5058 2782 3551 5290 5170 9693 5590 5608 2778 VASOPRESSIN REGULATION OF WATER HOMEOSTASIS%PATHWHIZ%PW000447 Vasopressin Regulation of Water Homeostasis 2778 55970 554 2782 5567 2792 108 2492 INTRACELLULAR SIGNALLING THROUGH FSH RECEPTOR AND FOLLICLE STIMULATING HORMONE%PATHWHIZ%PW000448 Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone 5567 2792 108 837856 2492 1081 2778 55970 5499 1385 2782 INTRACELLULAR SIGNALLING THROUGH HISTAMINE H2 RECEPTOR AND HISTAMINE%PATHWHIZ%PW000449 Intracellular Signalling Through Histamine H2 Receptor and Histamine 837856 3274 2778 5499 1385 2782 5567 2792 108 INTRACELLULAR SIGNALLING THROUGH LHCGR RECEPTOR AND LUTEINIZING HORMONE CHORIOGONADOTROPIN%SMPDB%SMP0000338 Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone Choriogonadotropin 5567 2792 108 3973 837856 1081 2778 5499 1385 2782 3972 INTRACELLULAR SIGNALLING THROUGH PGD2 RECEPTOR AND PROSTAGLANDIN D2%SMPDB%SMP0000343 Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 2778 5729 2782 5567 2792 108 INTRACELLULAR SIGNALLING THROUGH PROSTACYCLIN RECEPTOR AND PROSTACYCLIN%SMPDB%SMP0000354 Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin 5739 2778 2782 5567 2792 108 4634 4638 FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS%SMPDB%SMP0000358 Fc Epsilon Receptor I Signaling in Mast Cells 3635 5295 5594 4067 5894 3596 5290 5608 5609 2534 3567 3565 207 6416 9846 5604 3845 5605 5606 5163 6850 7124 5321 4893 6654 3265 3562 1437 2207 2206 2205 695 3937 2885 1432 5335 5599 10451 5578 27040 5879 INSULIN SIGNALLING%PATHWHIZ%PW000454 Insulin Signalling 3643 6517 3667 5604 5605 2308 5294 8660 5594 6464 5894 6654 3265 5170 146850 2885 3630 5599 207 DIMETHYLGLYCINE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000484 Dimethylglycine Dehydrogenase Deficiency 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 HYPERGLYCINEMIA, NON-KETOTIC%SMPDB%SMP0000485 Hyperglycinemia, Non-Ketotic 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 DOPA-RESPONSIVE DYSTONIA%SMPDB%SMP0000486 DOPA-Responsive Dystonia 231 5805 2644 873 2643 5860 6697 1719 HYPERPHENYLALANINEMIA DUE TO GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE DEFICIENCY%SMPDB%SMP0000487 Hyperphenylalaninemia Due to Guanosine Triphosphate Cyclohydrolase Deficiency 231 5805 2644 873 2643 5860 6697 1719 HYPERPHENYLALANINEMIA DUE TO 6-PYRUVOYLTETRAHYDROPTERIN SYNTHASE DEFICIENCY (PTPS)%SMPDB%SMP0000488 Hyperphenylalaninemia Due to 6-Pyruvoyltetrahydropterin Synthase Deficiency (ptps) 231 5805 2644 873 2643 5860 6697 1719 HYPERPHENYLALANINEMIA DUE TO DHPR-DEFICIENCY%PATHWHIZ%PW000465 Hyperphenylalaninemia Due to DHPR-Deficiency 231 5805 2644 873 2643 5860 6697 1719 SEGAWA SYNDROME%PATHWHIZ%PW000466 Segawa Syndrome 231 5805 2644 873 2643 5860 6697 1719 SEPIAPTERIN REDUCTASE DEFICIENCY%PATHWHIZ%PW000467 Sepiapterin Reductase Deficiency 231 5805 2644 873 2643 5860 6697 1719 CARNOSINURIA, CARNOSINEMIA%SMPDB%SMP0000493 Carnosinuria, Carnosinemia 4329 8639 84735 18 217 1807 1806 2571 51733 TYROSINEMIA, TRANSIENT, OF THE NEWBORN%PATHWHIZ%PW000470 Tyrosinemia, Transient, of the Newborn 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 GALACTOSEMIA II (GALK)%SMPDB%SMP0000495 Galactosemia II (GALK) 80146 2645 7358 5236 2584 2582 2592 7360 GALACTOSEMIA III%SMPDB%SMP0000496 Galactosemia III 80146 2645 7358 5236 2584 2582 2592 7360 TYROSINE HYDROXYLASE DEFICIENCY%SMPDB%SMP0000497 Tyrosine Hydroxylase Deficiency 5409 7054 1644 DOPAMINE BETA-HYDROXYLASE DEFICIENCY%SMPDB%SMP0000498 Dopamine beta-Hydroxylase Deficiency 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 BETA-MERCAPTOLACTATE-CYSTEINE DISULFIDURIA%SMPDB%SMP0000499 beta-Mercaptolactate-Cysteine Disulfiduria 2805 1491 3939 2730 1036 1497 833 4357 2729 5-OXOPROLINASE DEFICIENCY%PATHWHIZ%PW000476 5-Oxoprolinase Deficiency 119391 26873 290 2729 2937 2936 2876 124975 840 79017 2730 GAMMA-GLUTAMYLTRANSPEPTIDASE DEFICIENCY%SMPDB%SMP0000501 gamma-Glutamyltranspeptidase Deficiency 119391 26873 290 2729 2937 2936 2876 124975 840 79017 2730 MALONYL-COA DECARBOXYLASE DEFICIENCY%PATHWHIZ%PW000478 Malonyl-CoA Decarboxylase Deficiency 1629 1738 4329 31 5096 23417 34 38 18 92483 5095 593 594 26275 79611 84532 1892 84693 HYPOPHOSPHATASIA%SMPDB%SMP0000503 Hypophosphatasia 57026 8566 249 316 55163 CREATINE DEFICIENCY, GUANIDINOACETATE METHYLTRANSFERASE DEFICIENCY%PATHWHIZ%PW000480 Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 HYPERORNITHINEMIA WITH GYRATE ATROPHY (HOGA)%PATHWHIZ%PW000481 Hyperornithinemia with Gyrate Atrophy (HOGA) 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 HYPERORNITHINEMIA-HYPERAMMONEMIA-HOMOCITRULLINURIA [HHH-SYNDROME]%PATHWHIZ%PW000482 Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome] 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 L-ARGININE:GLYCINE AMIDINOTRANSFERASE DEFICIENCY%PATHWHIZ%PW000483 L-Arginine:Glycine Amidinotransferase Deficiency 8659 4842 4942 10166 5625 5009 2805 2628 1373 1152 2593 29920 383 2746 283208 1610 445 435 2058 57038 CHOLESTERYL ESTER STORAGE DISEASE%SMPDB%SMP0000508 Cholesteryl Ester Storage Disease 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 HYPER-IGD SYNDROME%SMPDB%SMP0000509 Hyper-IgD Syndrome 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 MEVALONIC ACIDURIA%SMPDB%SMP0000510 Mevalonic Aciduria 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 WOLMAN DISEASE%PATHWHIZ%PW000487 Wolman Disease 4598 10682 6713 1718 7108 6646 6307 3988 6309 10654 50814 9453 39 4047 4597 3156 2224 3422 2222 1595 51478 XANTHINURIA TYPE I%SMPDB%SMP0000512 Xanthinuria Type I 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 XANTHINURIA TYPE II%PATHWHIZ%PW000489 Xanthinuria Type II 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 GAMMA-CYSTATHIONASE DEFICIENCY (CTH)%PATHWHIZ%PW000490 gamma-Cystathionase Deficiency (CTH) 875 1491 HOMOCYSTINURIA, CYSTATHIONINE BETA-SYNTHASE DEFICIENCY%PATHWHIZ%PW000491 Homocystinuria, Cystathionine beta-Synthase Deficiency 875 1491 ADRENOLEUKODYSTROPHY, X-LINKED%PATHWHIZ%PW000492 Adrenoleukodystrophy, X-Linked 215 788 1384 5194 5195 2180 92960 54677 225 1376 CARNITINE-ACYLCARNITINE TRANSLOCASE DEFICIENCY%PATHWHIZ%PW000493 Carnitine-Acylcarnitine Translocase Deficiency 215 788 1384 5194 5195 2180 92960 54677 225 1376 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY%PATHWHIZ%PW000494 Glucose-6-phosphate Dehydrogenase Deficiency 6120 221823 22934 5211 25796 7086 51071 2821 2203 226 5236 5226 6888 64080 2539 RIBOSE-5-PHOSPHATE ISOMERASE DEFICIENCY%SMPDB%SMP0000519 Ribose-5-phosphate Isomerase Deficiency 6120 221823 22934 5211 25796 7086 51071 2821 2203 226 5236 5226 6888 64080 2539 TRANSALDOLASE DEFICIENCY%SMPDB%SMP0000520 Transaldolase Deficiency 6120 221823 22934 5211 25796 7086 51071 2821 2203 226 5236 5226 6888 64080 2539 3-HYDROXYISOBUTYRIC ACID DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000521 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 3-HYDROXYISOBUTYRIC ACIDURIA%PATHWHIZ%PW000498 3-Hydroxyisobutyric Aciduria 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 ISOBUTYRYL-COA DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000523 Isobutyryl-CoA Dehydrogenase Deficiency 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 ISOVALERIC ACIDEMIA%PATHWHIZ%PW000500 Isovaleric Acidemia 593 594 26275 3158 1892 217 316 5019 1738 3712 4329 5096 64087 34 35 36 38 18 3155 5095 10449 586 3028 27034 549 1629 11112 56922 FABRY DISEASE%SMPDB%SMP0000525 Fabry Disease 2581 123099 259230 10558 55331 410 2720 10825 2531 9517 8879 2629 2717 56848 9331 64781 8611 130367 9514 7357 7368 339221 125981 KRABBE DISEASE%PATHWHIZ%PW000502 Krabbe Disease 2581 123099 259230 10558 55331 410 2720 10825 2531 9517 8879 2629 2717 56848 9331 64781 8611 130367 9514 7357 7368 339221 125981 HYPERLYSINEMIA I, FAMILIAL%PATHWHIZ%PW000503 Hyperlysinemia I, Familial 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 HYPERLYSINEMIA II OR SACCHAROPINURIA%PATHWHIZ%PW000504 Hyperlysinemia II or Saccharopinuria 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 D-GLYCERIC ACIDURA%PATHWHIZ%PW000505 D-Glyceric Acidura 4023 3990 132158 2819 218 10554 231 57678 2820 8611 8612 FAMILIAL LIPOPROTEIN LIPASE DEFICIENCY%PATHWHIZ%PW000506 Familial Lipoprotein Lipase Deficiency 4023 3990 132158 2819 218 10554 231 57678 2820 8611 8612 GLYCOGENOSIS, TYPE VII. TARUI DISEASE%PATHWHIZ%PW000507 Glycogenosis, Type VII. Tarui Disease 5230 5223 5213 5224 2023 3099 130589 2821 226 2597 5313 669 6514 2538 SULFITE OXIDASE DEFICIENCY%PATHWHIZ%PW000508 Sulfite Oxidase Deficiency 6817 10380 6821 6820 9060 50515 MONOAMINE OXIDASE-A DEFICIENCY (MAO-A)%PATHWHIZ%PW000509 Monoamine Oxidase-A Deficiency (MAO-A) 4282 3081 7299 26 23498 2184 5409 2954 1644 124 1621 1312 218 4128 2805 1638 G(M2)-GANGLIOSIDOSIS: VARIANT B, TAY-SACHS DISEASE%SMPDB%SMP0000534 G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease 51005 5238 140838 55907 64841 10020 6675 3098 26503 3073 1118 10007 54187 80896 55577 2673 5973 ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY (APRT)%PATHWHIZ%PW000511 Adenine Phosphoribosyltransferase Deficiency (APRT) 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 MITOCHONDRIAL DNA DEPLETION SYNDROME-3%SMPDB%SMP0000536 Mitochondrial DNA Depletion Syndrome-3 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 MYOADENYLATE DEAMINASE DEFICIENCY%PATHWHIZ%PW000513 Myoadenylate Deaminase Deficiency 3704 100 10846 10606 84896 203 108 8833 2618 10201 221823 22978 5144 11164 270 471 353 3614 2987 2766 158 159 2983 318 957 9615 1716 6241 6240 5471 5198 7498 4860 377841 3251 7295 2977 CARNITINE PALMITOYL TRANSFERASE DEFICIENCY I%PATHWHIZ%PW000514 Carnitine Palmitoyl Transferase Deficiency I 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 LONG CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (LCAD)%PATHWHIZ%PW000515 Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 VERY-LONG-CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (VLCAD)%SMPDB%SMP0000540 Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD) 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 CARNITINE PALMITOYL TRANSFERASE DEFICIENCY II%PATHWHIZ%PW000517 Carnitine Palmitoyl Transferase Deficiency II 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 MEDIUM CHAIN ACYL-COA DEHYDROGENASE DEFICIENCY (MCAD)%PATHWHIZ%PW000518 Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD) 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY (MTHFRD)%PATHWHIZ%PW000519 Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) 1719 4522 8836 4524 10840 10841 10797 10588 25902 2356 113235 123263 LONG-CHAIN-3-HYDROXYACYL-COA DEHYDROGENASE DEFICIENCY (LCHAD)%PATHWHIZ%PW000520 Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase Deficiency (LCHAD) 10449 3028 51102 1892 3032 3030 5538 TRIFUNCTIONAL PROTEIN DEFICIENCY%SMPDB%SMP0000545 Trifunctional Protein Deficiency 33 2180 34 35 36 37 38 1374 3032 3030 10449 1376 1892 2639 CONGENITAL LACTIC ACIDOSIS%PATHWHIZ%PW000522 Congenital Lactic Acidosis 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 FUMARASE DEFICIENCY%SMPDB%SMP0000547 Fumarase Deficiency 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 MITOCHONDRIAL COMPLEX II DEFICIENCY%PATHWHIZ%PW000524 Mitochondrial Complex II Deficiency 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 2-KETOGLUTARATE DEHYDROGENASE COMPLEX DEFICIENCY%PATHWHIZ%PW000525 2-Ketoglutarate Dehydrogenase Complex Deficiency 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 PYRUVATE DEHYDROGENASE DEFICIENCY (E3)%SMPDB%SMP0000550 Pyruvate Dehydrogenase Deficiency (E3) 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 PYRUVATE DEHYDROGENASE DEFICIENCY (E2)%SMPDB%SMP0000551 Pyruvate Dehydrogenase Deficiency (E2) 51660 1431 3421 8802 55526 8801 50 1738 1737 3419 5162 6389 3420 5091 4190 6391 2271 6390 5160 6392 1743 GLYCOGEN SYNTHETASE DEFICIENCY%PATHWHIZ%PW000528 Glycogen Synthetase Deficiency 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 GLYCOGENOSIS, TYPE III. CORI DISEASE, DEBRANCHER GLYCOGENOSIS%PATHWHIZ%PW000529 Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 GLYCOGENOSIS, TYPE IV. AMYLOPECTINOSIS, ANDERSON DISEASE%SMPDB%SMP0000554 Glycogenosis, Type IV. Amylopectinosis, Anderson Disease 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 GLYCOGENOSIS, TYPE VI. HERS DISEASE%PATHWHIZ%PW000531 Glycogenosis, Type VI. Hers Disease 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 MUCOPOLYSACCHARIDOSIS VII. SLY SYNDROME%SMPDB%SMP0000556 Mucopolysaccharidosis VII. Sly Syndrome 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 SUCRASE-ISOMALTASE DEFICIENCY%PATHWHIZ%PW000533 Sucrase-Isomaltase Deficiency 6476 8972 7358 2990 3099 7360 2998 283209 2821 2645 178 278 2632 5236 5836 10720 PRIMARY HYPEROXALURIA II, PH2%SMPDB%SMP0000558 Primary Hyperoxaluria II, PH2 217 5313 55902 5105 1738 2739 1737 97 31 197257 5162 134526 38 4199 9380 5091 4190 5160 231 3029 3939 PYRUVATE KINASE DEFICIENCY%PATHWHIZ%PW000535 Pyruvate Kinase Deficiency 217 5313 55902 5105 1738 2739 1737 97 31 197257 5162 134526 38 4199 9380 5091 4190 5160 231 3029 3939 PHOSPHOENOLPYRUVATE CARBOXYKINASE DEFICIENCY 1 (PEPCK1)%SMPDB%SMP0000560 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 FRUCTOSURIA%SMPDB%SMP0000561 Fructosuria 229 5207 197258 29085 7264 5372 7167 4351 6652 5211 3098 8790 29925 231 2203 2762 226 3795 FRUCTOSE-1,6-DIPHOSPHATASE DEFICIENCY%SMPDB%SMP0000562 Fructose-1,6-diphosphatase Deficiency 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW000539 Triosephosphate Isomerase Deficiency 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 MULTIPLE CARBOXYLASE DEFICIENCY, NEONATAL OR EARLY ONSET FORM%SMPDB%SMP0000564 Multiple Carboxylase Deficiency, Neonatal or Early Onset Form 686 28972 3141 32 AROMATASE DEFICIENCY%SMPDB%SMP0000565 Aromatase Deficiency 412 6783 6820 6715 3283 3293 10720 3292 6718 1588 7367 1586 17-ALPHA-HYDROXYLASE DEFICIENCY (CYP17)%PATHWHIZ%PW000542 17-alpha-Hydroxylase Deficiency (CYP17) 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 SUCCINIC SEMIALDEHYDE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000567 Succinic Semialdehyde Dehydrogenase Deficiency 2730 124454 55577 2673 8659 8833 2806 2729 2937 2936 5859 7915 5471 64841 18 1373 2571 790 2746 27165 2875 2752 SHORT-CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE DEFICIENCY (SCHAD)%PATHWHIZ%PW000544 Short-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency (SCHAD) 33 35 10449 3028 38 79611 1892 3033 SUCCINYL COA: 3-KETOACID COA TRANSFERASE DEFICIENCY%SMPDB%SMP0000569 Succinyl CoA: 3-Ketoacid CoA Transferase Deficiency 38 622 3155 5019 HOMOCYSTINURIA-MEGALOBLASTIC ANEMIA DUE TO DEFECT IN COBALAMIN METABOLISM, CBLG COMPLEMENTATION TYPE%SMPDB%SMP0000570 Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type 22921 4141 4144 1491 262 6470 4507 1786 259307 875 27430 253827 635 6723 4524 55349 PYRIDOXINE DEPENDENCY WITH SEIZURES%SMPDB%SMP0000571 Pyridoxine Dependency with Seizures 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 FANCONI-BICKEL SYNDROME%SMPDB%SMP0000572 Fanconi-Bickel Syndrome 5230 5223 5213 5224 2023 3099 130589 2821 226 2597 5313 669 6514 2538 GLYCOGENOSIS, TYPE IB%SMPDB%SMP0000573 Glycogenosis, Type IB 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 GLYCOGENOSIS, TYPE IC%SMPDB%SMP0000574 Glycogenosis, Type IC 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 11-BETA-HYDROXYLASE DEFICIENCY (CYP11B1)%SMPDB%SMP0000575 11-beta-Hydroxylase Deficiency (CYP11B1) 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 21-HYDROXYLASE DEFICIENCY (CYP21)%SMPDB%SMP0000576 21-Hydroxylase Deficiency (CYP21) 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 CORTICOSTERONE METHYL OXIDASE I DEFICIENCY (CMO I)%PATHWHIZ%PW000553 Corticosterone Methyl Oxidase I Deficiency (CMO I) 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 CORTICOSTERONE METHYL OXIDASE II DEFICIENCY (CMO II)%SMPDB%SMP0000578 Corticosterone Methyl Oxidase II Deficiency (CMO II) 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 CONGENITAL DISORDER OF GLYCOSYLATION CDG-IID%PATHWHIZ%PW000555 Congenital Disorder of Glycosylation CDG-IId 2592 124583 2538 7360 51727 3906 7355 6513 2683 4831 GLUT-1 DEFICIENCY SYNDROME%SMPDB%SMP0000580 GLUT-1 Deficiency Syndrome 2592 124583 2538 7360 51727 3906 7355 6513 2683 4831 GLYCOGENOSIS, TYPE IA. VON GIERKE DISEASE%SMPDB%SMP0000581 Glycogenosis, Type IA. Von Gierke Disease 3939 2203 51660 2542 226 2597 53354 5236 669 5105 6514 2538 7167 8402 5223 5224 2023 3099 130589 5091 4191 2821 JOUBERT SYNDROME%SMPDB%SMP0000582 Joubert Syndrome 23236 5293 200576 5728 56623 55697 55626 8867 5305 3635 1956 10423 5295 5286 5297 8821 8678 30849 5289 9896 2064 8394 BLUE DIAPER SYNDROME%SMPDB%SMP0000583 Blue Diaper Syndrome 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 LYSINURIC PROTEIN INTOLERANCE (LPI)%SMPDB%SMP0000585 Lysinuric Protein Intolerance (LPI) 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 COAGULATION%SMPDB%SMP0000586 Coagulation 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 ANGIOTENSIN METABOLISM%SMPDB%SMP0000587 Angiotensin Metabolism 5972 183 1636 STRIATED MUSCLE CONTRACTION%PATHWHIZ%PW000564 Striated Muscle Contraction 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 GASTRIC ACID PRODUCTION%SMPDB%SMP0000589 Gastric Acid Production 6754 759 3274 1193 495 496 6750 2520 887 1131 IBUPROFEN METABOLISM PATHWAY%PATHWHIZ%PW000566 Ibuprofen Metabolism Pathway 1558 10525 1557 54600 1576 54575 5742 54659 54658 5479 5743 10961 3309 51726 1559 7363 9356 7364 9376 9601 10130 23753 64714 BENAZEPRIL METABOLISM PATHWAY%SMPDB%SMP0000591 Benazepril Metabolism Pathway 1636 CILAZAPRIL METABOLISM PATHWAY%SMPDB%SMP0000592 Cilazapril Metabolism Pathway 1636 ENALAPRIL METABOLISM PATHWAY%SMPDB%SMP0000593 Enalapril Metabolism Pathway 1636 FOSINOPRIL METABOLISM PATHWAY%SMPDB%SMP0000594 Fosinopril Metabolism Pathway 1636 MOEXIPRIL METABOLISM PATHWAY%SMPDB%SMP0000595 Moexipril Metabolism Pathway 1636 QUINAPRIL METABOLISM PATHWAY%SMPDB%SMP0000596 Quinapril Metabolism Pathway 1636 RAMIPRIL METABOLISM PATHWAY%SMPDB%SMP0000597 Ramipril Metabolism Pathway 1636 SPIRAPRIL METABOLISM PATHWAY%SMPDB%SMP0000598 Spirapril Metabolism Pathway 1636 TRANDOLAPRIL METABOLISM PATHWAY%PATHWHIZ%PW000575 Trandolapril Metabolism Pathway 1636 IRINOTECAN METABOLISM PATHWAY%SMPDB%SMP0000600 Irinotecan Metabolism Pathway 64714 10525 1577 54600 1576 1244 54575 8824 9429 54658 5479 10961 3309 51726 10599 5243 9601 4363 10130 1066 590 7150 23753 ETOPOSIDE METABOLISM PATHWAY%PATHWHIZ%PW000577 Etoposide Metabolism Pathway 5742 54658 5479 5743 10961 3309 51726 7153 7155 5243 9601 4353 10130 23753 64714 10525 1577 1576 8714 TENIPOSIDE METABOLISM PATHWAY%SMPDB%SMP0000602 Teniposide Metabolism Pathway 7153 1577 1576 4353 GEMCITABINE METABOLISM PATHWAY%PATHWHIZ%PW000579 Gemcitabine Metabolism Pathway 6241 6240 51727 64078 7298 2030 9154 1503 1635 1633 50484 4830 30833 CYCLOPHOSPHAMIDE METABOLISM PATHWAY%PATHWHIZ%PW000580 Cyclophosphamide Metabolism Pathway 1548 1559 2944 1558 1557 1555 1576 216 218 IFOSFAMIDE METABOLISM PATHWAY%PATHWHIZ%PW000581 Ifosfamide Metabolism Pathway 1558 1555 1577 1576 216 218 1548 1559 TAMOXIFEN METABOLISM PATHWAY%PATHWHIZ%PW000582 Tamoxifen Metabolism Pathway 1565 54575 2099 54657 2328 6817 2326 1555 1577 1576 CAPECITABINE METABOLISM PATHWAY%SMPDB%SMP0000607 Capecitabine Metabolism Pathway 7298 1066 1890 978 9154 FLUOROURACIL METABOLISM PATHWAY%SMPDB%SMP0000608 Fluorouracil Metabolism Pathway 7298 MERCAPTOPURINE METABOLISM PATHWAY%SMPDB%SMP0000609 Mercaptopurine Metabolism Pathway 5471 64078 7498 3177 9153 3251 7172 2030 132 3614 316 10057 8833 10257 5879 CLOPIDOGREL METABOLISM PATHWAY%PATHWHIZ%PW000586 Clopidogrel Metabolism Pathway 64805 1559 1557 1544 1555 1577 5243 1576 5444 TICLOPIDINE METABOLISM PATHWAY%SMPDB%SMP0000611 Ticlopidine Metabolism Pathway 64805 ESOMEPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000588 Esomeprazole Metabolism Pathway 495 496 OMEPRAZOLE METABOLISM PATHWAY%SMPDB%SMP0000613 Omeprazole Metabolism Pathway 495 496 LANSOPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000590 Lansoprazole Metabolism Pathway 495 496 PANTOPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000591 Pantoprazole Metabolism Pathway 495 496 RABEPRAZOLE METABOLISM PATHWAY%PATHWHIZ%PW000592 Rabeprazole Metabolism Pathway 495 496 CIMETIDINE METABOLISM PATHWAY%PATHWHIZ%PW000593 Cimetidine Metabolism Pathway 3274 FOSPHENYTOIN (ANTIARRHYTHMIC) METABOLISM PATHWAY%SMPDB%SMP0000618 Fosphenytoin (Antiarrhythmic) Metabolism Pathway 6331 6641 6640 6645 FELODIPINE METABOLISM PATHWAY%SMPDB%SMP0000619 Felodipine Metabolism Pathway 782 9254 775 LIDOCAINE (LOCAL ANAESTHETIC) METABOLISM PATHWAY%SMPDB%SMP0000620 Lidocaine (Local Anaesthetic) Metabolism Pathway 1544 1576 6324 6336 CODEINE METABOLISM PATHWAY%PATHWHIZ%PW000597 Codeine Metabolism Pathway 7364 1576 1565 4988 MORPHINE METABOLISM PATHWAY%SMPDB%SMP0000622 Morphine Metabolism Pathway 51726 7363 7364 9601 7366 10130 23753 64714 10525 54576 54659 54658 5479 10961 4988 3309 HEROIN METABOLISM PATHWAY%PATHWHIZ%PW000599 Heroin Metabolism Pathway 8824 1066 590 4988 METHADONE METABOLISM PATHWAY%SMPDB%SMP0000624 Methadone Metabolism Pathway 1551 4988 2903 2902 1558 1557 1555 1576 1565 116443 IMIPRAMINE METABOLISM PATHWAY%PATHWHIZ%PW000601 Imipramine Metabolism Pathway 1557 1544 1576 1565 6530 6532 DESIPRAMINE METABOLISM PATHWAY%PATHWHIZ%PW000602 Desipramine Metabolism Pathway 1565 6530 6532 CITALOPRAM METABOLISM PATHWAY%PATHWHIZ%PW000603 Citalopram Metabolism Pathway 1557 1565 1551 6532 316 4128 4129 NICOTINE METABOLISM PATHWAY%PATHWHIZ%PW000604 Nicotine Metabolism Pathway 54657 1548 2328 1555 1137 54600 1136 316 1141 ADEFOVIR DIPIVOXIL METABOLISM PATHWAY%PATHWHIZ%PW000605 Adefovir Dipivoxil Metabolism Pathway 203 204 4830 4831 TENOFOVIR METABOLISM PATHWAY%PATHWHIZ%PW000606 Tenofovir Metabolism Pathway 203 204 4830 4831 PREDNISONE METABOLISM PATHWAY%PATHWHIZ%PW000607 Prednisone Metabolism Pathway 1576 PREDNISOLONE METABOLISM PATHWAY%PATHWHIZ%PW000608 Prednisolone Metabolism Pathway 2908 3320 FELBAMATE METABOLISM PATHWAY%SMPDB%SMP0000633 Felbamate Metabolism Pathway 124 1576 1571 218 CARBAMAZEPINE METABOLISM PATHWAY%PATHWHIZ%PW000610 Carbamazepine Metabolism Pathway 1558 1557 1555 1577 1576 1551 2052 VALPROIC ACID METABOLISM PATHWAY%SMPDB%SMP0000635 Valproic Acid Metabolism Pathway 54659 3032 3712 3030 1548 1559 116285 1555 36 1962 3028 VENLAFAXINE METABOLISM PATHWAY%PATHWHIZ%PW000612 Venlafaxine Metabolism Pathway 1557 5243 1576 1565 6530 6532 TRAMADOL METABOLISM PATHWAY%PATHWHIZ%PW000613 Tramadol Metabolism Pathway 7364 1555 1576 1565 1244 54576 6580 LEVOMETHADYL ACETATE METABOLISM PATHWAY%PATHWHIZ%PW000614 Levomethadyl Acetate Metabolism Pathway 1551 CLOMIPRAMINE METABOLISM PATHWAY%PATHWHIZ%PW000615 Clomipramine Metabolism Pathway 1557 1544 1576 1565 ACETAMINOPHEN METABOLISM PATHWAY%PATHWHIZ%PW000616 Acetaminophen Metabolism Pathway 5243 9601 7366 10130 64714 1576 54578 54658 5479 10057 6822 10257 51726 4363 6783 1571 23753 6818 10525 6817 1544 2952 54600 1565 2950 9429 10961 3309 1548 DOXEPIN METABOLISM PATHWAY%PATHWHIZ%PW000617 Doxepin Metabolism Pathway 1557 1544 1576 1565 1559 NEVIRAPINE METABOLISM PATHWAY%PATHWHIZ%PW000618 Nevirapine Metabolism Pathway 1555 1577 1576 1565 216 89845 54575 1559 CELECOXIB METABOLISM PATHWAY%SMPDB%SMP0000644 Celecoxib Metabolism Pathway 124 125 1576 1565 54575 5742 5743 1559 FLUOXETINE METABOLISM PATHWAY%SMPDB%SMP0000646 Fluoxetine Metabolism Pathway 1557 1577 1576 1565 6532 1559 THIOGUANINE METABOLISM PATHWAY%PATHWHIZ%PW000623 Thioguanine Metabolism Pathway 3251 SORAFENIB METABOLISM PATHWAY%PATHWHIZ%PW000624 Sorafenib Metabolism Pathway 9601 10130 23753 64714 1558 10525 1555 54600 1576 54658 5479 10961 3309 51726 1559 LAMIVUDINE METABOLISM PATHWAY%PATHWHIZ%PW000625 Lamivudine Metabolism Pathway 4830 5833 10257 30833 6582 6581 51727 5130 5230 5243 4363 6580 6817 1633 1244 56994 8714 9429 DOXORUBICIN METABOLISM PATHWAY%SMPDB%SMP0000650 Doxorubicin Metabolism Pathway 374291 4846 5243 4363 8644 7498 10928 10327 873 874 1244 85413 9429 4720 5447 4722 1728 ARTEMETHER METABOLISM PATHWAY%PATHWHIZ%PW000627 Artemether Metabolism Pathway 7364 1577 54600 1576 MYCOPHENOLIC ACID METABOLISM PATHWAY%PATHWHIZ%PW000628 Mycophenolic Acid Metabolism Pathway 7364 5243 1066 1558 3615 3614 1577 54600 1576 54577 1244 54576 28234 8824 9429 10599 ROSIGLITAZONE METABOLISM PATHWAY%PATHWHIZ%PW000629 Rosiglitazone Metabolism Pathway 1558 1559 10599 WARBURG EFFECT%PATHWHIZ%PW000630 Warburg Effect 51660 1431 5313 8802 5315 55526 6888 8801 50 1738 1737 3419 5230 5211 6566 6389 25796 2023 3099 5091 1743 2597 3421 229 5226 6514 2539 5162 22934 48 5224 6510 3420 4190 6391 2271 6390 5160 7086 6392 3417 2746 27165 2821 3939 PHENINDIONE ACTION PATHWAY%SMPDB%SMP0000655 Phenindione Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 DICOUMAROL ACTION PATHWAY%PATHWHIZ%PW000632 Dicoumarol Action Pathway 3818 2147 2158 2157 1277 2244 2266 5327 5340 2243 2155 2165 2153 2152 2162 2161 2160 79001 2677 2159 BOPINDOLOL ACTION PATHWAY%SMPDB%SMP0000657 Bopindolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 CARTEOLOL ACTION PATHWAY%PATHWHIZ%PW000634 Carteolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 TIMOLOL ACTION PATHWAY%PATHWHIZ%PW000636 Timolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 SOTALOL ACTION PATHWAY%SMPDB%SMP0000660 Sotalol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 EPINEPHRINE ACTION PATHWAY%PATHWHIZ%PW000638 Epinephrine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 DOBUTAMINE ACTION PATHWAY%PATHWHIZ%PW000639 Dobutamine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 ISOPRENALINE ACTION PATHWAY%SMPDB%SMP0000663 Isoprenaline Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 ARBUTAMINE ACTION PATHWAY%SMPDB%SMP0000664 Arbutamine Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 AMIODARONE ACTION PATHWAY%PATHWHIZ%PW000642 Amiodarone Action Pathway 7169 7168 3760 30819 3761 153 3759 10975 476 477 478 5577 6546 3752 3753 6548 1739 3757 90550 5350 10060 9992 6641 6640 480 481 482 483 144245 486 488 3762 10021 3764 6833 3767 6331 775 6645 3775 6262 23439 9254 5573 5575 5576 1129 2778 782 8912 5566 3784 8913 3741 5567 5568 LEVOBUNOLOL ACTION PATHWAY%SMPDB%SMP0000666 Levobunolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 METIPRANOLOL ACTION PATHWAY%PATHWHIZ%PW000644 Metipranolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 BEVANTOLOL ACTION PATHWAY%PATHWHIZ%PW000645 Bevantolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 PRACTOLOL ACTION PATHWAY%PATHWHIZ%PW000646 Practolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 BUPRANOLOL ACTION PATHWAY%SMPDB%SMP0000670 Bupranolol Action Pathway 1739 3757 5350 6262 10060 9254 9992 5573 6641 6640 480 481 482 483 1129 144245 782 486 488 8912 5566 3762 3784 8913 3741 10021 3764 6833 3767 6331 7169 7168 3760 30819 3761 153 3759 476 477 478 775 6546 6645 3752 3775 3753 TRAMADOL ACTION ACTION PATHWAY%SMPDB%SMP0000671 Tramadol Action Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 PROPOXYPHENE ACTION PATHWAY%PATHWHIZ%PW000649 Propoxyphene Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 LEVORPHANOL ACTION PATHWAY%SMPDB%SMP0000673 Levorphanol Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 ANILERIDINE ACTION PATHWAY%SMPDB%SMP0000674 Anileridine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 DIPHENOXYLATE ACTION PATHWAY%SMPDB%SMP0000675 Diphenoxylate Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 DEZOCINE ACTION PATHWAY%PATHWHIZ%PW000653 Dezocine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 LEVOMETHADYL ACETATE ACTION ACTION PATHWAY%SMPDB%SMP0000677 Levomethadyl Acetate Action Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 METHADYL ACETATE ACTION PATHWAY%PATHWHIZ%PW000655 Methadyl Acetate Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 3-METHYLTHIOFENTANYL ACTION PATHWAY%PATHWHIZ%PW000656 3-Methylthiofentanyl Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 DIMETHYLTHIAMBUTENE ACTION PATHWAY%SMPDB%SMP0000680 Dimethylthiambutene Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 ETHYLMORPHINE ACTION PATHWAY%SMPDB%SMP0000681 Ethylmorphine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 LEUCINE STIMULATION ON INSULIN SIGNALING%SMPDB%SMP0000682 Leucine Stimulation on Insulin Signaling 5294 8660 6198 7248 8140 146850 2475 3630 207 7249 3643 6009 3667 1978 1977 LEVALLORPHAN ACTION PATHWAY%SMPDB%SMP0000683 Levallorphan Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 BUPRENORPHINE ACTION PATHWAY%SMPDB%SMP0000684 Buprenorphine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 ALVIMOPAN ACTION PATHWAY%SMPDB%SMP0000685 Alvimopan Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 PENTAZOCINE ACTION PATHWAY%SMPDB%SMP0000686 Pentazocine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 NALTREXONE ACTION PATHWAY%PATHWHIZ%PW000664 Naltrexone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 NALOXONE ACTION PATHWAY%SMPDB%SMP0000688 Naloxone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 DIHYDROMORPHINE ACTION PATHWAY%PATHWHIZ%PW000666 Dihydromorphine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 KETOBEMIDONE ACTION PATHWAY%SMPDB%SMP0000690 Ketobemidone Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 NALBUPHINE ACTION PATHWAY%SMPDB%SMP0000691 Nalbuphine Action Pathway 6531 6530 5443 30819 6532 1141 773 476 1137 477 478 3751 4986 4988 2903 2902 1812 9254 6324 3350 480 481 482 483 782 486 116443 148 5126 6336 ANTIPYRINE ACTION PATHWAY%SMPDB%SMP0000692 Antipyrine Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 ANTRAFENINE ACTION PATHWAY%SMPDB%SMP0000693 Antrafenine Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 CARPROFEN ACTION PATHWAY%SMPDB%SMP0000694 Carprofen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 ETORICOXIB ACTION PATHWAY%SMPDB%SMP0000695 Etoricoxib Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 FENOPROFEN ACTION PATHWAY%SMPDB%SMP0000696 Fenoprofen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 FLURBIPROFEN ACTION PATHWAY%SMPDB%SMP0000697 Flurbiprofen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 MAGNESIUM SALICYLATE ACTION PATHWAY%PATHWHIZ%PW000675 Magnesium Salicylate Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 LUMIRACOXIB ACTION PATHWAY%SMPDB%SMP0000699 Lumiracoxib Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 LORNOXICAM ACTION PATHWAY%PATHWHIZ%PW000677 Lornoxicam Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 PHENYLBUTAZONE ACTION PATHWAY%PATHWHIZ%PW000678 Phenylbutazone Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 NEPAFENAC ACTION PATHWAY%PATHWHIZ%PW000679 Nepafenac Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 TRISALICYLATE-CHOLINE ACTION PATHWAY%PATHWHIZ%PW000680 Trisalicylate-Choline Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 TOLMETIN ACTION PATHWAY%PATHWHIZ%PW000681 Tolmetin Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 TIAPROFENIC ACID ACTION PATHWAY%PATHWHIZ%PW000682 Tiaprofenic Acid Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 TENOXICAM ACTION PATHWAY%SMPDB%SMP0000706 Tenoxicam Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 SALSALATE ACTION PATHWAY%SMPDB%SMP0000707 Salsalate Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 SALICYLATE-SODIUM ACTION PATHWAY%SMPDB%SMP0000708 Salicylate-Sodium Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 SALICYLIC ACID ACTION PATHWAY%SMPDB%SMP0000709 Salicylic Acid Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 ACETAMINOPHEN ACTION PATHWAY%SMPDB%SMP0000710 Acetaminophen Action Pathway 4051 127281 113612 11283 4056 5740 2053 1558 1579 1555 873 1573 4048 239 8529 8644 9536 5730 1571 240 242 6916 2876 2678 100137049 246 247 5742 5743 TOBRAMYCIN ACTION PATHWAY%PATHWHIZ%PW000688 Tobramycin Action Pathway 947096 TIGECYCLINE ACTION PATHWAY%PATHWHIZ%PW000689 Tigecycline Action Pathway 947096 ARBEKACIN ACTION PATHWAY%PATHWHIZ%PW000690 Arbekacin Action Pathway 947096 PAROMOMYCIN ACTION PATHWAY%PATHWHIZ%PW000691 Paromomycin Action Pathway 947096 METHYLHISTIDINE METABOLISM%PATHWHIZ%PW000692 Methylhistidine Metabolism 60 THYROID HORMONE SYNTHESIS%PATHWHIZ%PW000693 Thyroid Hormone Synthesis 7038 6528 7173 1536 50507 1535 50506 53905 50508 APPARENT MINERALOCORTICOID EXCESS SYNDROME%SMPDB%SMP0000717 Apparent Mineralocorticoid Excess Syndrome 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 3-BETA-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000718 3-beta-Hydroxysteroid Dehydrogenase Deficiency 1585 1584 1583 3284 3283 1109 3291 3290 6718 1589 1586 2-AMINOADIPIC 2-OXOADIPIC ACIDURIA%SMPDB%SMP0000719 2-Aminoadipic 2-Oxoadipic Aciduria 6542 38 3033 1743 51166 83884 501 1892 51268 55526 1738 2639 10157 27-HYDROXYLASE DEFICIENCY%PATHWHIZ%PW000697 27-Hydroxylase Deficiency 3988 8309 9023 6342 9420 1593 1582 1581 3295 23600 570 10998 6718 10858 80270 51302 1109 3-PHOSPHOGLYCERATE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0000721 3-Phosphoglycerate Dehydrogenase Deficiency 29958 63826 29968 275 211 189 2731 27232 217 4128 5723 1738 10993 2617 2628 1757 6472 6301 132158 23464 26227 2593 1491 6470 CYSTINOSIS, OCULAR NONNEPHROPATHIC%PATHWHIZ%PW000699 Cystinosis, Ocular Nonnephropathic 2805 1491 3939 2730 1036 1497 833 4357 2729 CYSTINURIA%PATHWHIZ%PW000700 Cystinuria 23428 1187 8170 55089 476 477 478 4306 6505 54716 6582 6340 9356 9056 9057 6520 480 481 9990 482 483 8140 486 6337 6557 6339 6559 6338 11136 6519 FOLATE MALABSORPTION, HEREDITARY%PATHWHIZ%PW000701 Folate Malabsorption, Hereditary 1719 4522 8836 4524 10840 10841 10797 10588 25902 2356 113235 123263 FRUCTOSE INTOLERANCE, HEREDITARY%PATHWHIZ%PW000702 Fructose Intolerance, Hereditary 229 5207 197258 29085 7264 5372 7167 4351 6652 5211 3098 8790 29925 231 2203 2762 226 3795 TEMOCAPRIL ACTION PATHWAY%PATHWHIZ%PW000710 Temocapril Action Pathway 5972 183 1636 ROXATIDINE ACETATE ACTION PATHWAY%PATHWHIZ%PW000711 Roxatidine Acetate Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 METIAMIDE ACTION PATHWAY%PATHWHIZ%PW000712 Metiamide Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 BETAZOLE ACTION PATHWAY%PATHWHIZ%PW000713 Betazole Action Pathway 6754 759 3274 1193 495 496 6750 2520 887 1131 ACTIVATION OF PKC THROUGH G PROTEIN-COUPLED RECEPTOR%PATHWHIZ%PW000726 Activation of PKC Through G Protein-Coupled Receptor 2776 3708 5578 23236 GLYCOLYSIS AND PYRUVATE DEHYDROGENASE%SMPDB%SMP0000807 Glycolysis and Pyruvate Dehydrogenase 948424 946179 948412 948753 946527 947679 947415 99706872 948130 945032 947410 945372 946230 946880 946209 948409 948118 944794 946632 948117 948535 947414 945068 945651 GLUCONEOGENESIS FROM L-MALIC ACID%SMPDB%SMP0000839 Gluconeogenesis from L-Malic Acid 945032 947410 945372 946209 948409 946947 93777709 917020 946632 948535 947414 948039 948424 948753 945667 947679 947415 948659 946031 948130 GALACTITOL AND GALACTONATE DEGRADATION%SMPDB%SMP0000840 Galactitol and Galactonate Degradation 947644 946610 75172213 946633 946641 946598 946636 947637 948207 99706872 948196 946230 2847766 75205406 GLYCOLYSIS%PATHWHIZ%PW000839 Glycolysis 838676 840895 829940 824077 816672 FRUCTOSE METABOLISM%PATHWHIZ%PW000913 Fructose Metabolism 946632 946676 947414 945068 946677 946179 946879 946527 947679 947415 948130 945032 946672 946209 948409 GLYCEROL METABOLISM%PATHWHIZ%PW000914 Glycerol Metabolism 946632 948535 945068 946179 948412 948753 946735 946713 946733 948130 946230 946704 946209 948409 947414 945651 948424 948423 946725 946527 947679 947415 947955 99706872 945032 948125 948422 947410 945372 946880 GLYCEROL METABOLISM II%PATHWHIZ%PW000915 Glycerol Metabolism II 946632 948535 945068 946179 948412 948753 946735 946713 946733 948130 946230 946704 946209 948409 947414 945651 948423 946725 946527 947679 947415 947955 99706872 945032 948125 948422 947410 945372 946880 GLYCEROL METABOLISM III (SN-GLYCERO-3-PHOSPHOETHANOLAMINE)%PATHWHIZ%PW000916 Glycerol Metabolism III (sn-Glycero-3-Phosphoethanolamine) 946632 948535 945068 946179 948412 948753 946735 946713 946733 948130 946230 946704 946209 948409 947414 945651 948424 948423 946725 946527 947679 947415 947955 99706872 945032 948125 948422 947410 945372 946880 GLYCEROL METABOLISM IV (GLYCEROPHOSPHOGLYCEROL)%PATHWHIZ%PW000917 Glycerol Metabolism IV (Glycerophosphoglycerol) 946632 948535 945068 946179 948412 948753 946735 946713 946733 948130 946230 946704 946209 948409 947414 945651 948424 948423 946725 946527 947679 947415 947955 99706872 945032 948125 948422 947410 945372 946880 GLYCEROL METABOLISM V (GLYCEROPHOSPHOSERINE)%PATHWHIZ%PW000918 Glycerol Metabolism V (Glycerophosphoserine) 946632 948535 945068 946179 948412 948753 946735 946713 946733 948130 946230 946704 946209 948409 947414 945651 948424 948423 946725 946527 947679 947415 947955 99706872 945032 948125 948422 947410 945372 946880 THE ONCOGENIC ACTION OF 2-HYDROXYGLUTARATE%SMPDB%SMP0002291 The Oncogenic Action of 2-Hydroxyglutarate 5162 48 3420 6391 2271 6390 5160 6392 3417 27165 51660 1431 8802 55526 8801 50 1738 1737 3419 3418 946802 6389 5091 1743 3421 THE ONCOGENIC ACTION OF SUCCINATE%PATHWHIZ%PW002360 The Oncogenic Action of Succinate 5162 48 3420 6391 2271 6390 5160 6392 3417 51660 1431 8802 55526 8801 50 1738 1737 3419 3418 112399 6389 112398 5091 1743 54583 1468 3421 THE ONCOGENIC ACTION OF FUMARATE%PATHWHIZ%PW002363 The Oncogenic Action of Fumarate 5162 48 3420 6391 2271 6390 5160 6392 3417 51660 1431 8802 55526 8801 50 1738 1737 3419 3418 112399 6389 112398 5091 1743 54583 1468 3421 GLUTAMINOLYSIS AND CANCER%SMPDB%SMP0002298 Glutaminolysis and Cancer 9056 6566 6389 5091 1743 3421 5162 946850 47 4199 92745 6510 3420 6391 2271 946772 6390 5160 6392 2746 6509 27165 3939 51660 1431 8802 55526 2806 8801 50 1738 1737 3419 26292 3418 GLYCOLYSIS I%SMPDB%SMP0002312 Glycolysis I 853395 855808 854457 851541 851620 853207 852128 851193 853155 852495 SARCOSINE ONCOMETABOLITE PATHWAY%SMPDB%SMP0002313 Sarcosine Oncometabolite Pathway 6472 4144 57153 23446 6470 29958 501 27232 27430 635 55349 4548 1757 FRUCTOSE METABOLISM%PATHWHIZ%PW002390 Fructose Metabolism 854699 853984 853624 852128 850614 852639 853286 852495 854644 ETHANOL FERMENTATION%SMPDB%SMP0002356 Ethanol Fermentation 851193 853155 852495 853395 854457 855368 851541 851620 853207 852128 850733 850469 852978 850825 855808 THE ONCOGENIC ACTION OF L-2-HYDROXYGLUTARATE IN HYDROXYGLUTARIC ACIDURIA%PATHWHIZ%PW002451 The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxyglutaric aciduria 5162 48 3420 6391 2271 6390 5160 6392 3417 2746 27165 51660 1431 8802 55526 8801 50 1738 1737 3419 3418 6389 5091 1743 79944 3421 THE ONCOGENIC ACTION OF D-2-HYDROXYGLUTARATE IN HYDROXYGLUTARIC ACIDURIA%SMPDB%SMP0002359 The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxyglutaric aciduria 5162 48 728294 3420 6391 2271 6390 5160 6392 3417 2746 27165 51660 1431 8802 55526 8801 50 1738 1737 3419 3418 6389 5091 1743 79944 3421 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW002481 Starch and Sucrose Metabolism 856374 855321 852495 852530 855303 851564 854872 856137 851167 856705 852423 850962 852920 852128 850569 853199 854362 852286 855353 854644 851055 851007 851646 850614 852639 850317 851848 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW002495 Inositol Phosphate Metabolism 851753 851910 854815 856442 INOSITOL METABOLISM%SMPDB%SMP0002397 Inositol Metabolism 856442 851102 850574 855983 850941 855618 854815 852394 855454 855860 GLUCONEOGENESIS FROM L-MALIC ACID%PATHWHIZ%PW002518 Gluconeogenesis from L-Malic Acid 815842 839527 FLAVONOID BIOSYNTHESIS%SMPDB%SMP0012021 Flavonoid Biosynthesis 834951 831241 817599 828387 824287 830693 842469 824678 834291 829551 818686 PHOTOSYNTHESIS%SMPDB%SMP0012089 Photosynthesis 844728 844768 844802 817429 836789 837358 816652 827996 827877 844730 840098 844775 844731 844733 844770 844773 844738 842635 839449 825246 841033 840021 844787 839918 844788 844781 843450 826892 827223 844749 838622 837178 844745 844746 817606 844748 836525 815382 816672 844790 825797 844753 844754 842016 828984 844750 844794 844795 844751 820461 843029 844757 844758 836751 826551 841653 822277 824572 844245 CALVIN-BENSON CYCLE%PATHWHIZ%PW012957 Calvin-Benson Cycle 840098 844754 843450 822277 816652 824572 820461 816672 825246 842635 843029 FRUCTOSE METABOLISM%SMPDB%SMP0012445 Fructose Metabolism 835272 829034 829043 817697 837752 835871 831759 840953 837221 838689 PHOSPHATIDYLCHOLINE BIOSYNTHESIS%SMPDB%SMP0014212 Phosphatidylcholine Biosynthesis 5130 10390 23761 5833 10400 1119 DE NOVO TRIACYLGLYCEROL BIOSYNTHESIS%SMPDB%SMP0015896 De Novo Triacylglycerol Biosynthesis 57678 8694 23175 2819 10554 CARDIOLIPIN BIOSYNTHESIS%SMPDB%SMP0020986 Cardiolipin Biosynthesis 57678 8760 55326 9489 54675 114971 2819 PHOSPHATIDYLETHANOLAMINE BIOSYNTHESIS%SMPDB%SMP0029731 Phosphatidylethanolamine Biosynthesis 10390 23761 5833 9791 1119 ANDROSTENEDIONE METABOLISM%SMPDB%SMP0030406 Androstenedione Metabolism 3309 1109 51726 3290 9601 10130 23753 64714 3293 10525 6718 1588 1584 54658 5479 6715 10961 ESTRONE METABOLISM%SMPDB%SMP0030880 Estrone Metabolism 9601 6783 10130 23753 64714 3292 10525 1577 1543 1312 54658 5479 10961 3309 51726 BCR-ABL ACTION IN CML PATHOGENESIS%SMPDB%SMP0031692 BCR-ABL Action in CML Pathogenesis 2475 6502 867 6776 9846 5295 6198 7157 6654 4193 572 3717 4609 1027 2885 598 1399 1398 IMATINIB INHIBITION OF BCR-ABL%SMPDB%SMP0031694 Imatinib Inhibition of BCR-ABL 2885 598 1399 1398 2475 6502 867 6776 9846 5295 6198 5243 7157 6654 6580 4193 572 3717 4609 1027 DASATINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032594 Dasatinib Inhibition of BCR-ABL 2475 6502 867 6776 9846 5295 6198 7157 6654 4193 572 3717 4609 1027 2885 598 1399 1398 NILOTINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032595 Nilotinib Inhibition of BCR-ABL 2475 6502 867 6776 9846 5295 6198 7157 6654 4193 572 3717 4609 1027 2885 598 1399 1398 BOSUTINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032596 Bosutinib Inhibition of BCR-ABL 2475 6502 867 6776 9846 5295 6198 7157 6654 4193 572 3717 4609 1027 2885 598 1399 1398 BAFETINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032597 Bafetinib Inhibition of BCR-ABL 2475 6502 867 6776 9846 5295 6198 7157 6654 4193 572 3717 4609 1027 2885 598 1399 1398 PONATINIB INHIBITION OF BCR-ABL%PATHWHIZ%PW032598 Ponatinib Inhibition of BCR-ABL 2475 6502 867 6776 9846 5295 6198 7157 6654 4193 572 3717 4609 1027 2885 598 1399 1398 LAFUTIDINE H2-ANTIHISTAMINE ACTION%PATHWHIZ%PW051946 Lafutidine H2-Antihistamine Action 6754 759 3274 1193 495 496 6750 2520 887 1131 CHLORPHENAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW057579 Chlorphenamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PHENIRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0056662 Pheniramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DEXCHLORPHENIRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0056811 Dexchlorpheniramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BROMPHENIRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058500 Brompheniramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DEXBROMPHENIRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058503 Dexbrompheniramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TRIPROLIDINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057581 Triprolidine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DIMETINDENE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057582 Dimetindene H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 MEPYRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057583 Mepyramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ANTAZOLINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057584 Antazoline H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CHLOROPYRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058510 Chloropyramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TALASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW058511 Talastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TRIPELENNAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0057587 Tripelennamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 HISTAPYRRODINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058732 Histapyrrodine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 METHAPYRILENE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058741 Methapyrilene H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 THONZYLAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059696 Thonzylamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DIPHENHYDRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058785 Diphenhydramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CARBINOXAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058797 Carbinoxamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DOXYLAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059730 Doxylamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ORPHENADRINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059735 Orphenadrine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BROMODIPHENHYDRAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059740 Bromodiphenhydramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CLEMASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059823 Clemastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CHLORPHENOXAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059836 Chlorphenoxamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DIPHENYLPYRALINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059841 Diphenylpyraline H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PHENYLTOLOXAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059850 Phenyltoloxamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CYCLIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059857 Cyclizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CHLORCYCLIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058931 Chlorcyclizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 HYDROXYZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058936 Hydroxyzine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 MECLIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059891 Meclizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BUCLIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0058964 Buclizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 OXATOMIDE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059044 Oxatomide H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CETIRIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW059995 Cetirizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CINNARIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059110 Cinnarizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 LEVOCETIRIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060053 Levocetirizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PROMETHAZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060150 Promethazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ALIMEMAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059689 Alimemazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CYPROHEPTADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059694 Cyproheptadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PHENBENZAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060645 Phenbenzamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 FENETHAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059707 Fenethazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 HYDROXYETHYLPROMETHAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059710 Hydroxyethylpromethazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ISOTHIPENDYL H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060659 Isothipendyl H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 MEQUITAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059720 Mequitazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 METHDILAZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059730 Methdilazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 OXOMEMAZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060682 Oxomemazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 AZATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059865 Azatadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 KETOTIFEN H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060812 Ketotifen H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DOXEPIN H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060816 Doxepin H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ACRIVASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW060826 Acrivastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ASTEMIZOLE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0059897 Astemizole H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BEPOTASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060058 Bepotastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BILASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061119 Bilastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 LORATADINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061144 Loratadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DESLORATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060201 Desloratadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 EBASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061153 Ebastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TERFENADINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061157 Terfenadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 FEXOFENADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060218 Fexofenadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 LEVOCABASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060224 Levocabastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 MIZOLASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060230 Mizolastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 RUPATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060235 Rupatadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 OLOPATADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060740 Olopatadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 AZELASTINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0060741 Azelastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 THIAZINAMIUM H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061692 Thiazinamium H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 QUIFENADINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061693 Quifenadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BETAHISTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061694 Betahistine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 EMEDASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW061990 Emedastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 FLUNARIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0061047 Flunarizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 MEBHYDROLIN H1-ANTIHISTAMINE ACTION%SMPDB%SMP0061052 Mebhydrolin H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PHENINDAMINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW062141 Phenindamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 EPINASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW062142 Epinastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TOLPROPAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062621 Tolpropamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 EMBRAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062622 Embramine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 LATREPIRDINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062623 Latrepirdine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 THENYLDIAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062624 Thenyldiamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PROPIOMAZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW063580 Propiomazine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 CLOCINIZINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062788 Clocinizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 HOMOCHLORCYCLIZINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW063751 Homochlorcyclizine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TEMELASTINE H1-ANTIHISTAMINE ACTION%PATHWHIZ%PW063837 Temelastine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 ALCAFTADINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062881 Alcaftadine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 BAMIPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062882 Bamipine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 DEPTROPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062883 Deptropine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 QUETIAPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062884 Quetiapine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 MIRTAZAPINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062885 Mirtazapine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PIMETHIXENE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062886 Pimethixene H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 PYRROBUTAMINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062887 Pyrrobutamine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 THENALIDINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062894 Thenalidine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 TRITOQUALINE H1-ANTIHISTAMINE ACTION%SMPDB%SMP0062895 Tritoqualine H1-Antihistamine Action 54331 4790 2776 3708 3269 2782 5579 23236 HISTAMINE H1 RECEPTOR ACTIVATION%SMPDB%SMP0063452 Histamine H1 Receptor Activation 54331 4790 2776 3708 3269 2782 5579 23236 GLYCOLYSIS%SMPDB%SMP0063478 Glycolysis 18663 68401 12183 21991 15275 230163 319625 433182 56421 14751 14447 18746 239606 18648 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW064563 Pentose Phosphate Pathway 18642 19895 67763 71336 14120 100198 21351 230163 66646 110208 232449 83553 14751 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0063614 Fructose and Mannose Degradation 18642 21991 14120 15275 230163 11676 GLUCONEOGENESIS%PATHWHIZ%PW064594 Gluconeogenesis 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 INOSITOL METABOLISM%PATHWHIZ%PW064607 Inositol Metabolism 225326 18707 74055 66461 101490 234729 75669 16332 218441 277360 INOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0063630 Inositol Phosphate Metabolism 16332 58242 277360 69718 STARCH AND SUCROSE METABOLISM%SMPDB%SMP0063673 Starch and Sucrose Metabolism 110006 22239 15275 14751 LYSOPHOSPHATIDIC ACID LPA1 SIGNALLING%SMPDB%SMP0063746 Lysophosphatidic Acid LPA1 Signalling 6093 1902 54331 3708 6722 2782 107 207 23236 LYSOPHOSPHATIDIC ACID LPA2 SIGNALLING%SMPDB%SMP0063753 Lysophosphatidic Acid LPA2 Signalling 23236 6093 54331 3708 6722 2782 107 207 9170 LYSOPHOSPHATIDIC ACID LPA3 SIGNALLING%SMPDB%SMP0063755 Lysophosphatidic Acid LPA3 Signalling 54331 2778 3708 2782 107 207 23236 23566 LYSOPHOSPHATIDIC ACID LPA4 SIGNALLING%SMPDB%SMP0063756 Lysophosphatidic Acid LPA4 Signalling 207 23236 6093 2846 54331 2778 3708 6722 2782 107 LYSOPHOSPHATIDIC ACID LPA5 SIGNALLING%SMPDB%SMP0063757 Lysophosphatidic Acid LPA5 Signalling 207 57121 23236 6093 54331 2778 3708 6722 2782 107 LYSOPHOSPHATIDIC ACID LPA6 SIGNALLING%PATHWHIZ%PW064749 Lysophosphatidic Acid LPA6 Signalling 54331 2778 10161 6722 2782 107 207 6093 ACTIVATION OF CAMP-DEPENDENT PROTEIN KINASE, PKA%SMPDB%SMP0063764 Activation of cAMP-dependent protein kinase, PKA 5566 5577 2782 5567 2792 5568 55811 2778 5573 5575 5576 AHR SIGNAL TRANSDUCTION PATHWAY%PATHWHIZ%PW064763 Ahr Signal Transduction Pathway 3320 405 196 APOPTOTIC DNA FRAGMENTATION AND TISSUE HOMEOSTASIS%SMPDB%SMP0063772 Apoptotic DNA Fragmentation and Tissue Homeostasis 836 790 7153 1676 840 3148 3146 3002 2021 BTG FAMILY PROTEINS AND CELL CYCLE REGULATION%SMPDB%SMP0063773 BTG Family Proteins and Cell Cycle Regulation 3276 10036 4803 5925 3219 595 694 7157 2246 7832 NITRIC OXIDE SIGNALING PATHWAY%SMPDB%SMP0063777 Nitric Oxide Signaling Pathway 7498 5530 217 5578 5567 4842 2903 2902 808 1742 3708 116443 ION CHANNELS AND THEIR FUNCTIONAL ROLE IN VASCULAR ENDOTHELIUM%SMPDB%SMP0063778 Ion Channels and Their Functional Role in Vascular Endothelium 5592 5593 7222 7223 59341 9132 2977 56479 2983 57113 2982 3785 3786 55811 4846 P53 SIGNALING PATHWAY%PATHWHIZ%PW064774 P53 Signaling Pathway 5111 581 1019 891 595 596 1017 983 1026 898 317 1869 4616 5925 PHOSPHOLIPASE C SIGNALING PATHWAY%SMPDB%SMP0063783 Phospholipase C Signaling Pathway 5294 146850 5335 5578 207 23236 7409 RAS SIGNALING PATHWAY%SMPDB%SMP0063784 Ras Signaling Pathway 387 1147 598 842 2002 998 10451 317 207 5898 4303 5337 54205 5900 5879 5604 5595 4088 4089 5894 3265 10928 5290 572 TNF STRESS RELATED SIGNALING%PATHWHIZ%PW064784 TNF Stress Related Signaling 1432 5599 4214 8737 10010 8517 835 6416 8738 3725 5606 8717 7186 4790 4792 7124 5871 3551 5608 5609 1147 466 RAC 1 CELL MOTILITY SIGNALING PATHWAY%SMPDB%SMP0063795 Rac 1 Cell Motility Signaling Pathway 1026 896 10451 4214 4633 3984 60 5337 5879 10487 8936 4638 23647 6198 4660 5111 5156 5058 10928 1020 1072 595 CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES%SMPDB%SMP0063805 Cadmium Induces DNA Synthesis and Proliferation in Macrophages 4790 5594 4792 5595 5970 5894 3265 23236 3708 775 776 778 5578 779 5579 5604 GROWTH HORMONE SIGNALING PATHWAY%PATHWHIZ%PW064811 Growth Hormone Signaling Pathway 2688 2885 3630 5335 6777 5578 6776 3643 5777 6517 3667 5604 8651 5594 5595 6464 5894 6654 3265 2690 6195 3717 EGF SIGNALLING PATHWAY%SMPDB%SMP0063810 EGF Signalling Pathway 6773 6772 6654 6774 2353 3265 3716 1457 1950 2885 2002 6722 5335 5599 5578 5579 1956 5595 6464 5894 4214 6416 5921 6778 5604 3725 GNRH SIGNALING PATHWAY%PATHWHIZ%PW064816 GnRH Signaling Pathway 5579 5337 1839 1958 815 1956 9254 5594 5894 163688 23236 2778 782 5609 100137049 2798 10746 3708 2796 468 5566 107 81 4313 4214 6714 5604 3725 5606 6654 3265 1081 2767 2885 2488 775 1432 776 2002 778 5599 4323 998 3972 5578 779 NF-KB SIGNALING PATHWAY%PATHWHIZ%PW064818 NF-kB Signaling Pathway 8772 4790 7189 4792 7124 9020 3554 7316 3654 10454 7099 7132 7133 5970 6885 8202 3552 3551 10645 1147 84254 4214 8737 8517 4615 8717 COMPLEMENT PATHWAY%PATHWHIZ%PW064819 Complement Pathway 727 716 629 717 5648 718 729 4153 10747 1675 730 731 710 721 712 713 735 714 715 ALTERNATIVE COMPLEMENT PATHWAY%SMPDB%SMP0063815 Alternative Complement Pathway 718 729 1675 730 5199 731 735 727 629 UBIQUITIN–PROTEASOME PATHWAY%SMPDB%SMP0063816 Ubiquitin–Proteasome Pathway 5682 5683 5684 5685 10273 5686 7324 5719 10537 7316 5710 7317 5690 5691 5692 5693 5694 5695 7314 5706 5687 5688 5689 5700 5701 5702 5704 5705 LECTIN-INDUCED COMPLEMENT PATHWAY%SMPDB%SMP0063898 Lectin-Induced Complement Pathway 721 735 727 717 5648 718 729 10747 4153 730 731 TOLL-LIKE RECEPTOR PATHWAY 1%PATHWHIZ%PW064909 Toll-Like Receptor Pathway 1 3725 5606 929 4790 7189 114609 4792 5465 2353 23643 54472 51284 1432 2002 5610 5599 3654 10454 7099 7098 5970 6885 3551 7097 23118 5608 51295 1147 4214 8517 6416 54106 4615 CLASSICAL COMPLEMENT PATHWAY%PATHWHIZ%PW065057 Classical Complement Pathway 730 731 721 712 713 735 714 715 727 716 717 718 729 CXCR4 SIGNALING PATHWAY%SMPDB%SMP0064625 CXCR4 Signaling Pathway 2792 2185 5829 2776 1398 5335 5604 5747 9564 4790 5594 4792 5595 5288 6387 5894 7852 2782 3265 2770 D4-GDI SIGNALING PATHWAY%SMPDB%SMP0066935 D4-GDI Signaling Pathway 5551 9743 3002 394 142 397 841 842 843 317 834 836 54205 3725 T CELL RECEPTOR SIGNALING PATHWAY%SMPDB%SMP0066977 T Cell Receptor Signaling Pathway 5778 27040 915 3932 5879 916 917 5294 919 5295 5595 6464 5970 5530 5894 5532 5290 2534 4775 4214 6416 4776 10125 5604 3725 7409 808 4790 4792 4772 6654 4773 2353 3265 2885 2002 7316 5335 5599 5533 5578 7535 5579 STAT3 SIGNALING PATHWAY%PATHWHIZ%PW068597 Stat3 Signaling Pathway 7297 3716 5594 6774 2475 TOLL-LIKE RECEPTOR PATHWAY 2%SMPDB%SMP0069593 Toll-Like Receptor Pathway 2 929 4790 7189 7100 114609 4792 23643 949101 54472 51284 1432 5599 3654 10454 10333 7099 7098 5970 6885 3551 257397 7097 7096 23118 51295 1147 51311 4214 8517 6416 54106 4615 EPO SIGNALING PATHWAY%PATHWHIZ%PW070692 EPO Signaling Pathway 5604 3725 5595 6464 5894 6654 2353 2056 3265 3717 2885 2057 2002 5335 5599 6776 5777 FAS SIGNALING PATHWAY ( CD95 )%PATHWHIZ%PW070709 FAS signaling pathway ( CD95 ) 8772 5783 5062 84823 397 1677 1676 355 6709 356 5599 8767 11124 836 1616 839 5591 4000 4001 6885 5058 142 840 841 843 4214 6416 8837 3725 5925 BCR SIGNALING PATHWAY%PATHWHIZ%PW070885 BCR Signaling Pathway 3725 7409 808 6850 4772 6654 4773 2353 3265 29760 695 2885 973 974 2002 5335 5599 5533 5578 5579 5879 5595 4067 6464 5530 5894 5532 84876 4775 4214 4776 5604 CARDIOLIPIN BIOSYNTHESIS (BARTH SYNDROME)%SMPDB%SMP0074684 Cardiolipin Biosynthesis (Barth Syndrome) 57678 8760 55326 9489 54675 114971 2819 SUCCINATE SIGNALLING%PATHWHIZ%PW084312 Succinate Signalling 7099 3091 283208 3553 23410 114548 NAD+ SIGNALLING PATHWAY (CANCER)%PATHWHIZ%PW084315 NAD+ Signalling Pathway (Cancer) 1728 23411 10135 64802 65220 349565 7157 952 23057 84883 NAD+ SIGNALLING AND AGING%SMPDB%SMP0084271 NAD+ Signalling and Aging 23057 1728 23411 10135 64802 6095 9575 65220 349565 4881 10891 SUCCINATE SIGNALLING DURING INFLAMMATION%SMPDB%SMP0084634 Succinate Signalling During Inflammation 4790 5594 5595 1385 3551 56670 23236 1147 5742 5578 5600 8517 4846 BILE ACID DIRECT SIGNALLING PATHWAY (1)%PATHWHIZ%PW087627 Bile Acid Direct Signalling Pathway (1) 9971 151306 6555 6579 10257 BILE ACID INDIRECT SIGNALLING PATHWAY%SMPDB%SMP0086851 Bile Acid Indirect Signalling Pathway 9971 9965 6555 152831 2264 2263 2261 2260 WARBURG EFFECT%SMPDB%SMP0086930 Warburg Effect 100198 104112 21351 66945 67834 64602 66925 69719 20501 433182 55951 20916 11676 14447 18746 243996 14194 18293 27402 110208 15926 11428 83553 15929 14751 17449 239606 67680 66052 12974 18663 18642 19895 12183 12040 14661 14782 14660 15275 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0087197 Fructose and Mannose Degradation 510978 618691 513483 513158 513586 515263 534594 514161 614868 317748 519181 100138313 508954 282304 281543 508683 GLYCOLYSIS%PATHWHIZ%PW088241 Glycolysis 281181 512571 515067 538710 404148 280808 533785 515263 616676 506544 282357 281543 281141 GLUCONEOGENESIS%PATHWHIZ%PW088242 Gluconeogenesis 510749 282855 282523 282357 534402 281543 281141 281181 513483 515067 538710 404148 338471 280808 533785 515263 616676 767977 281306 INOSITOL METABOLISM%PATHWHIZ%PW088261 Inositol Metabolism 282306 507414 530577 541067 508591 509394 518488 614890 533202 517263 504735 282309 281869 615813 281986 281865 527278 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW088265 Pentose Phosphate Pathway 513453 781227 513483 616120 280808 515263 613376 445425 534558 281179 533764 534402 508683 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW088271 Starch and Sucrose Metabolism 515687 537188 515366 280808 786335 539383 517397 615745 280798 281564 534402 281565 505472 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW088275 Inositol Phosphate Metabolism 534793 518488 534029 510684 618855 541067 281869 509394 615813 281865 WARBURG EFFECT%SMPDB%SMP0087270 Warburg Effect 281480 513453 281181 407109 280808 534599 535182 613338 506888 533910 282446 505775 281179 281235 280682 507476 537713 327696 508683 514939 512571 515067 286840 512995 616120 517402 509983 338471 614145 515263 613376 767977 613610 280976 520260 445425 282357 281785 282355 281481 281141 FRUCTOSE AND MANNOSE DEGRADATION%SMPDB%SMP0087296 Fructose and Mannose Degradation 24638 24849 300741 25741 24189 25058 24788 25659 291095 24192 501167 24362 246232 300089 GLYCOLYSIS%PATHWHIZ%PW088336 Glycolysis 24383 24189 24333 25059 24651 24642 292804 25634 65152 24959 24849 313843 GLUCONEOGENESIS%SMPDB%SMP0087318 Gluconeogenesis 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 INOSITOL METABOLISM%PATHWHIZ%PW088354 Inositol Metabolism 29688 83523 171458 29390 307842 252899 171088 65052 500709 306808 64473 290651 363131 114558 24655 80849 295230 81677 116482 59319 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW088358 Pentose Phosphate Pathway 83688 362383 24377 25741 64524 24189 362706 292804 29562 690945 24362 STARCH AND SUCROSE METABOLISM%PATHWHIZ%PW088364 Starch and Sucrose Metabolism 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW088368 Inositol Phosphate Metabolism 500709 306808 64473 290651 116699 80849 81677 294292 29688 50560 83523 171458 171088 WARBURG EFFECT%PATHWHIZ%PW088382 Warburg Effect 50655 292804 100360180 363061 64524 25059 25630 94173 24368 24644 298596 299201 24383 83688 157074 171087 24959 289950 289217 362383 24377 24399 25741 361272 24333 24398 24651 298942 79250 25027 24479 81654 170587 114096 29483 24551 114597 NUCLEOTIDE SUGARS METABOLISM%SMPDB%SMP0087384 Nucleotide Sugars Metabolism 39065 39031 38076 38760 44010 38911 33935 43191 GLYCOLYSIS%SMPDB%SMP0087391 Glycolysis 43582 46246 38697 43183 33351 43447 35728 38109 43191 36060 42620 35886 INOSITOL METABOLISM%SMPDB%SMP0087396 Inositol Metabolism 31376 31247 33236 42807 32285 38137 47396 39404 37360 42850 41096 37033 41543 39841 41701 35671 40346 42446 39391 2768892 PENTOSE PHOSPHATE PATHWAY%SMPDB%SMP0087400 Pentose Phosphate Pathway 36060 39132 35265 246599 35692 41027 37804 32974 35886 32013 43183 44010 36358 31007 INOSITOL PHOSPHATE METABOLISM%PATHWHIZ%PW088427 Inositol Phosphate Metabolism 32285 37465 41701 39226 35671 40346 39404 2768892 37360 33137 33236 39841 WARBURG EFFECT%SMPDB%SMP0087420 Warburg Effect 41027 43689 42832 37804 34414 32974 35886 32013 31185 42808 31605 43183 31406 39988 37228 35728 44291 36060 42268 42620 44001 46246 34021 33351 36020 43437 35590 42689 32940 31198 38447 31579 38109 43191 41340 41360 36396 246599 41326 33461 GLYCOLYSIS%PATHWHIZ%PW088465 Glycolysis 174423 4363084 180583 173227 174844 180601 172744 176788 172751 INOSITOL METABOLISM%PATHWHIZ%PW088478 Inositol Metabolism 174792 173241 178284 174381 172280 187517 183790 189456 172128 174827 172477 172589 191426 174762 178537 173581 177345 SPHINGOLIPID METABOLISM%PATHWHIZ%PW088482 Sphingolipid Metabolism 173389 178535 179663 174001 174071 179660 266646 179194 180524 190668 183197 189124 183002 172603 174507 172423 173327 176857 PENTOSE PHOSPHATE PATHWAY%PATHWHIZ%PW088490 Pentose Phosphate Pathway 266822 176043 180583 177906 173911 173843 173227 176016 176788 175995 177202 174781 178046 178398 INOSITOL PHOSPHATE METABOLISM%SMPDB%SMP0087496 Inositol Phosphate Metabolism 191426 259365 174792 173241 172221 189456 172128 172779 178284 172477 187517 WARBURG EFFECT%SMPDB%SMP0087527 Warburg Effect 181570 180583 177906 176437 3565996 177108 171965 172655 173227 179945 176059 172751 174692 177202 178398 181324 178130 179041 181724 181108 259500 179616 172744 181528 177775 176788 177555 175995 174423 174482 177971 176121 178387 178046 179674 260040 174282 180641 180601 BILE ACID DIRECT SIGNALLING PATHWAY (2)%PATHWHIZ%PW090771 Bile Acid Direct Signalling Pathway (2) 151306 2740 6555 CD40L SIGNALLING PATHWAY%SMPDB%SMP0089759 CD40L Signalling Pathway 7187 4790 7189 4792 3551 1843 1147 1432 7128 4214 8517 958 959 8518 G-PROTEIN SIGNALING THROUGH TUBBY PROTEINS%PATHWHIZ%PW090863 G-Protein Signaling Through Tubby Proteins 7275 1128 2776 3358 2782 2792 23236 G-SECRETASE MEDIATED ERBB4 SIGNALLING PATHWAY%PATHWHIZ%PW090995 g-Secretase Mediated ErbB4 Signalling Pathway 9542 5663 5578 2066 2065 6868 1956 ION CHANNEL AND PHORBAL ESTERS SIGNALING PATHWAY%SMPDB%SMP0090032 Ion Channel and Phorbal Esters Signaling Pathway 5335 5578 5579 5029 2185 CIRCADIAN RHYTHMS%SMPDB%SMP0090831 Circadian Rhythms 9575 5187 4881 1454 1407 HOP PATHWAY IN CARDIAC DEVELOPMENT%SMPDB%SMP0090879 Hop Pathway in Cardiac Development 84525 6722 1482 2626 LPS AND CITRATE SIGNALING AND INFLAMMATION%PATHWHIZ%PW101069 LPS and Citrate Signaling and Inflammation 6389 6576 3551 853155 4190 6391 23643 6390 6392 1147 1431 8517 31 4615 7099 929 4790 7189 47 114609 4792 4199 5970 PROTEIN SYNTHESIS: ALANINE%PATHWHIZ%PW101384 Protein Synthesis: Alanine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 16 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 ACTIVATION OF PKC THROUGH G PROTEIN-COUPLED RECEPTOR%SMPDB%SMP0108012 Activation of PKC Through G Protein-Coupled Receptor 81666 25262 24680 24654 FC EPSILON RECEPTOR I SIGNALING IN MAST CELLS%SMPDB%SMP0108224 Fc Epsilon Receptor I Signaling in Mast Cells 25155 499356 363875 24835 313050 25047 81504 81511 192213 116553 116630 54259 25441 116554 116590 25738 24605 24703 287287 293621 25316 81515 25513 24525 363855 25150 170851 24185 58960 24680 84477 NITRIC OXIDE SIGNALING PATHWAY%SMPDB%SMP0108236 Nitric Oxide Signaling Pathway 29495 24409 24408 24680 24244 24674 24598 293508 PHOSPHOLIPASE C SIGNALING PATHWAY%PATHWHIZ%PW109280 Phospholipase C Signaling Pathway 25738 24185 24680 24654 497932 CADMIUM INDUCES DNA SYNTHESIS AND PROLIFERATION IN MACROPHAGES%PATHWHIZ%PW109282 Cadmium Induces DNA Synthesis and Proliferation in Macrophages 309165 293621 24680 25023 24654 81736 50689 116590 24703 170851 25493 25262 PROTEIN SYNTHESIS: ARGININE%SMPDB%SMP0111853 Protein Synthesis: Arginine 6136 6171 6170 6173 5917 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: ASPARAGINE%SMPDB%SMP0111854 Protein Synthesis: Asparagine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 4677 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: ASPARTIC ACID%SMPDB%SMP0111858 Protein Synthesis: Aspartic Acid 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 1615 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: CYSTEINE%PATHWHIZ%PW112918 Protein Synthesis: Cysteine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 833 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: GLUTAMINE%SMPDB%SMP0111862 Protein Synthesis: Glutamine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 5859 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: GLUTAMIC ACID%PATHWHIZ%PW112922 Protein Synthesis: Glutamic Acid 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 2058 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: GLYCINE%PATHWHIZ%PW112928 Protein Synthesis: Glycine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 2617 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: HISTIDINE%PATHWHIZ%PW112929 Protein Synthesis: Histidine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 3035 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: ISOLEUCINE%SMPDB%SMP0111872 Protein Synthesis: Isoleucine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 3376 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: LEUCINE%SMPDB%SMP0111873 Protein Synthesis: Leucine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 51520 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: LYSINE%SMPDB%SMP0111874 Protein Synthesis: Lysine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 3735 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: METHIONINE%PATHWHIZ%PW112933 Protein Synthesis: Methionine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 4141 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: PHENYLALANINE%PATHWHIZ%PW112934 Protein Synthesis: Phenylalanine 6135 6134 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 2193 6194 6227 6229 6228 10056 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 PROTEIN SYNTHESIS: PROLINE%PATHWHIZ%PW113695 Protein Synthesis: Proline 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 2058 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: SERINE%PATHWHIZ%PW120517 Protein Synthesis: Serine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6301 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: THREONINE%PATHWHIZ%PW120525 Protein Synthesis: Threonine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6897 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: TRYPTOPHAN%PATHWHIZ%PW120526 Protein Synthesis: Tryptophan 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 7453 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: TYROSINE%PATHWHIZ%PW120527 Protein Synthesis: Tyrosine 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 8565 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 6137 PROTEIN SYNTHESIS: VALINE%PATHWHIZ%PW120528 Protein Synthesis: Valine 6137 6136 6171 6170 6173 6205 6128 6204 6207 6129 6206 6209 6208 10399 6142 6141 6188 6144 6187 6143 6146 6223 6189 6222 7311 6224 6147 6181 6139 6138 6218 6217 6230 6152 6232 6155 6154 6231 6157 6234 9349 6156 6159 6158 6235 6191 2197 23521 6193 6194 6227 6229 6228 11224 6164 6122 6165 6124 6168 6201 6167 6203 6125 6202 6169 25873 6160 6161 3921 7407 4736 6175 6130 6133 9045 6210 6176 6132 6135 6134 PROTEIN SYNTHESIS: ALANINE%PATHWHIZ%PW120529 Protein Synthesis: Alanine 67281 16898 57808 54217 76846 234734 19921 20005 267019 100503670 270106 16785 20044 20088 20042 66489 110954 56040 57294 114641 22186 20085 20084 19933 19899 66483 67891 66480 67097 19934 66481 67025 19942 19941 14694 20055 20054 68436 19981 67427 67945 27207 27367 68193 19988 19944 67186 19943 20091 20090 19946 19989 268449 20104 19951 76808 75617 20103 20102 20068 67115 22121 65019 26961 27176 54127 11837 27050 269261 27370 14109 67671 20115 66475 319195 67248 20116 26451 68052 GLYCOGEN STORAGE DISEASE TYPE 1A (GSD1A) OR VON GIERKE DISEASE%SMPDB%SMP0120488 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY%SMPDB%SMP0120583 Glucose-6-phosphate Dehydrogenase Deficiency 18642 19895 67763 71336 14120 100198 21351 230163 66646 110208 232449 83553 14751 RIBOSE-5-PHOSPHATE ISOMERASE DEFICIENCY%SMPDB%SMP0120584 Ribose-5-phosphate Isomerase Deficiency 18642 19895 67763 71336 14120 100198 21351 230163 66646 110208 232449 83553 14751 TRANSALDOLASE DEFICIENCY%SMPDB%SMP0120585 Transaldolase Deficiency 18642 19895 67763 71336 14120 100198 21351 230163 66646 110208 232449 83553 14751 GLYCOGENOSIS, TYPE VII. TARUI DISEASE%SMPDB%SMP0120596 Glycogenosis, Type VII. Tarui Disease 18663 68401 12183 21991 15275 230163 319625 433182 56421 14751 14447 18746 239606 18648 GLYCOGEN SYNTHETASE DEFICIENCY%PATHWHIZ%PW121872 Glycogen Synthetase Deficiency 110006 22239 15275 14751 GLYCOGENOSIS, TYPE III. CORI DISEASE, DEBRANCHER GLYCOGENOSIS%SMPDB%SMP0120617 Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis 110006 22239 15275 14751 GLYCOGENOSIS, TYPE IV. AMYLOPECTINOSIS, ANDERSON DISEASE%SMPDB%SMP0120618 Glycogenosis, Type IV. Amylopectinosis, Anderson Disease 110006 22239 15275 14751 GLYCOGENOSIS, TYPE VI. HERS DISEASE%SMPDB%SMP0120619 Glycogenosis, Type VI. Hers Disease 110006 22239 15275 14751 MUCOPOLYSACCHARIDOSIS VII. SLY SYNDROME%PATHWHIZ%PW121876 Mucopolysaccharidosis VII. Sly Syndrome 110006 22239 15275 14751 SUCRASE-ISOMALTASE DEFICIENCY%PATHWHIZ%PW121877 Sucrase-Isomaltase Deficiency 110006 22239 15275 14751 PHOSPHOENOLPYRUVATE CARBOXYKINASE DEFICIENCY 1 (PEPCK1)%PATHWHIZ%PW121880 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 FRUCTOSURIA%PATHWHIZ%PW121881 Fructosuria 18642 21991 14120 15275 230163 11676 FRUCTOSE-1,6-DIPHOSPHATASE DEFICIENCY%PATHWHIZ%PW121882 Fructose-1,6-diphosphatase Deficiency 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW121883 Triosephosphate Isomerase Deficiency 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 FANCONI-BICKEL SYNDROME%PATHWHIZ%PW121892 Fanconi-Bickel Syndrome 18663 68401 12183 21991 15275 230163 319625 433182 56421 14751 14447 18746 239606 18648 GLYCOGENOSIS, TYPE IB%PATHWHIZ%PW121893 Glycogenosis, Type IB 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 GLYCOGENOSIS, TYPE IC%PATHWHIZ%PW121894 Glycogenosis, Type IC 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 GLYCOGENOSIS, TYPE IA. VON GIERKE DISEASE%PATHWHIZ%PW121901 Glycogenosis, Type IA. Von Gierke Disease 14447 239606 71803 18648 68401 269614 12183 21991 14120 15275 230163 319625 74551 69719 433182 55951 14751 17448 FRUCTOSE INTOLERANCE, HEREDITARY%PATHWHIZ%PW121913 Fructose Intolerance, Hereditary 18642 21991 14120 15275 230163 11676 GLYCOGEN STORAGE DISEASE TYPE 1A (GSD1A) OR VON GIERKE DISEASE%PATHWHIZ%PW121967 Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY%PATHWHIZ%PW122063 Glucose-6-phosphate Dehydrogenase Deficiency 83688 362383 24377 25741 64524 24189 362706 292804 29562 690945 24362 RIBOSE-5-PHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW122064 Ribose-5-phosphate Isomerase Deficiency 83688 362383 24377 25741 64524 24189 362706 292804 29562 690945 24362 TRANSALDOLASE DEFICIENCY%SMPDB%SMP0120804 Transaldolase Deficiency 83688 362383 24377 25741 64524 24189 362706 292804 29562 690945 24362 GLYCOGENOSIS, TYPE VII. TARUI DISEASE%SMPDB%SMP0120815 Glycogenosis, Type VII. Tarui Disease 24383 24189 24333 25059 24651 24642 292804 25634 65152 24959 24849 313843 GLYCOGEN SYNTHETASE DEFICIENCY%PATHWHIZ%PW122096 Glycogen Synthetase Deficiency 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 GLYCOGENOSIS, TYPE III. CORI DISEASE, DEBRANCHER GLYCOGENOSIS%PATHWHIZ%PW122097 Glycogenosis, Type III. Cori Disease, Debrancher Glycogenosis 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 GLYCOGENOSIS, TYPE IV. AMYLOPECTINOSIS, ANDERSON DISEASE%SMPDB%SMP0120837 Glycogenosis, Type IV. Amylopectinosis, Anderson Disease 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 GLYCOGENOSIS, TYPE VI. HERS DISEASE%SMPDB%SMP0120838 Glycogenosis, Type VI. Hers Disease 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 MUCOPOLYSACCHARIDOSIS VII. SLY SYNDROME%SMPDB%SMP0120839 Mucopolysaccharidosis VII. Sly Syndrome 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 SUCRASE-ISOMALTASE DEFICIENCY%PATHWHIZ%PW122101 Sucrase-Isomaltase Deficiency 289827 286954 25059 83472 24434 497039 292804 685076 362029 64035 24385 PHOSPHOENOLPYRUVATE CARBOXYKINASE DEFICIENCY 1 (PEPCK1)%SMPDB%SMP0120843 Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1) 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 FRUCTOSURIA%PATHWHIZ%PW122105 Fructosuria 24638 24849 300741 25741 24189 25058 24788 25659 291095 24192 501167 24362 246232 300089 FRUCTOSE-1,6-DIPHOSPHATASE DEFICIENCY%PATHWHIZ%PW122106 Fructose-1,6-diphosphatase Deficiency 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 TRIOSEPHOSPHATE ISOMERASE DEFICIENCY%PATHWHIZ%PW122107 Triosephosphate Isomerase Deficiency 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 FANCONI-BICKEL SYNDROME%PATHWHIZ%PW122116 Fanconi-Bickel Syndrome 24383 24189 24333 25059 24651 24642 292804 25634 65152 24959 24849 313843 GLYCOGENOSIS, TYPE IB%PATHWHIZ%PW122117 Glycogenosis, Type IB 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 GLYCOGENOSIS, TYPE IC%PATHWHIZ%PW122118 Glycogenosis, Type IC 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 GLYCOGENOSIS, TYPE IA. VON GIERKE DISEASE%SMPDB%SMP0120864 Glycogenosis, Type IA. Von Gierke Disease 292804 171087 24959 24849 64201 24189 24333 25059 362282 81829 24642 25634 313843 24362 24383 171053 FRUCTOSE INTOLERANCE, HEREDITARY%SMPDB%SMP0120876 Fructose Intolerance, Hereditary 24638 24849 300741 25741 24189 25058 24788 25659 291095 24192 501167 24362 246232 300089 SUCCINATE SIGNALLING DURING INFLAMMATION%PATHWHIZ%PW122149 Succinate Signalling During Inflammation 24600 50689 84351 116590 81646 309295 24680 24654 81736 GROWTH HORMONE SIGNALING PATHWAY%SMPDB%SMP0120947 Growth Hormone Signaling Pathway 25139 24514 24391 170851 192213 81771 24680 85385 50689 116590 24506 25738 24703 293621 24918 116689 25235 25467 25126 81504 EGF SIGNALLING PATHWAY%SMPDB%SMP0120948 EGF Signalling Pathway 25313 81504 116549 314322 24514 363855 170851 192213 314436 24680 59323 501099 116554 25023 85385 50689 25738 24703 24516 293621 24918 25125 116667 25676 GNRH SIGNALING PATHWAY%SMPDB%SMP0120949 GnRH Signaling Pathway 63836 25194 363855 170851 81668 25096 24680 81662 81686 24516 64532 25400 116700 116667 81707 24654 81504 25447 25329 83805 79255 192213 25262 314436 59323 116554 25023 24330 117284 116590 24703 293621 64465 24244 25433 T CELL RECEPTOR SIGNALING PATHWAY%SMPDB%SMP0120959 T Cell Receptor Signaling Pathway 309165 246781 29434 24680 25155 307820 50522 85385 50689 363875 24516 300678 313050 116667 24674 25300 24675 81504 314322 81511 192213 314436 116554 25023 25738 24703 293621 24244 25710 81736 25513 363855 25150 170851 25493 BCR SIGNALING PATHWAY%SMPDB%SMP0120964 BCR Signaling Pathway 24516 313050 116667 24674 24675 81504 314322 192213 314436 116554 25023 171055 25738 24703 293621 100913063 24244 81515 170851 24680 25155 307820 499356 304496 85385 50689 363875 G-SECRETASE MEDIATED ERBB4 SIGNALLING PATHWAY%PATHWHIZ%PW122231 g-Secretase Mediated ErbB4 Signalling Pathway 29496 24680 59323 57027 29192 432361 ION CHANNEL AND PHORBAL ESTERS SIGNALING PATHWAY%SMPDB%SMP0120969 Ion Channel and Phorbal Esters Signaling Pathway 25738 24680 29597 25023 50646 KIDNEY FUNCTION- PROXIMAL CONVOLUTED TUBULE%SMPDB%SMP0121001 Kidney Function- Proximal Convoluted Tubule 6582 9356 23428 9056 8671 9057 6520 8140 55089 358 6548 759 6505 11136 6519 54716 KIDNEY FUNCTION - DESCENDING LIMB OF THE LOOP OF HENLE%SMPDB%SMP0121009 Kidney Function - Descending Limb of the Loop of Henle 358 KIDNEY FUNCTION - ASCENDING LIMB OF THE LOOP OF HENLE%PATHWHIZ%PW122277 Kidney Function - Ascending Limb of The Loop of Henle 478 5972 1187 6557 480 481 9990 482 483 486 476 477 KIDNEY FUNCTION - COLLECTING DUCT%PATHWHIZ%PW122278 Kidney Function - Collecting Duct 478 359 525 6337 6339 759 6338 6340 5972 6521 8170 480 481 360 482 483 486 476 477 KIDNEY FUNCTION - DISTAL CONVOLUTED TUBULE%SMPDB%SMP0121012 Kidney Function - Distal Convoluted Tubule 359 6546 6559 5972 1187 480 481 360 482 483 495 56302 496 486 476 477 478 PANCREAS FUNCTION - BETA CELL%PATHWHIZ%PW122285 Pancreas Function - Beta Cell 11069 6514 6844 6833 3710 55811 9254 9699 2782 1131 23236 54331 782 773 2776 2740 84254 5578 5864 PANCREAS FUNCTION - ALPHA CELL%PATHWHIZ%PW122296 Pancreas Function - Alpha Cell 2641 6645 6514 6833 782 6331 9254 773 6641 6640 MEVALONATE PATHWAY%SMPDB%SMP0121055 Mevalonate Pathway 4597 3157 3156 4598 6713 10654 2224 38 3422 2222 4047 BLOCH PATHWAY (CHOLESTEROL BIOSYNTHESIS)%SMPDB%SMP0121057 Bloch Pathway (Cholesterol Biosynthesis) 6307 6309 50814 1595 51478 10682 1718 3930 1717 KANDUTSCH-RUSSELL PATHWAY (CHOLESTEROL BIOSYNTHESIS)%SMPDB%SMP0121060 Kandutsch-Russell Pathway (Cholesterol Biosynthesis) 6307 6309 50814 1595 51478 10682 1718 3930 1717 ARSENATE DETOXIFICATION%PATHWHIZ%PW122396 Arsenate Detoxification 364 366 4860 9446 57412 6513 6517 EUMELANIN BIOSYNTHESIS%SMPDB%SMP0121124 Eumelanin Biosynthesis 7299 1638 ALDOSTERONE FROM STEROIDOGENESIS%SMPDB%SMP0121126 Aldosterone from Steroidogenesis 54331 1589 2776 1585 1583 2782 3283 185 PANCREAS FUNCTION - DELTA CELL%PATHWHIZ%PW122406 Pancreas Function - Delta Cell 782 9254 773 6750 6514 6833 2-AMINO-3-CARBOXYMUCONATE SEMIALDEHYDE DEGRADATION%SMPDB%SMP0121131 2-Amino-3-Carboxymuconate Semialdehyde Degradation 1743 130013 64577 55526 1738 FRUCTOSE METABOLISM%PATHWHIZ%PW122616 Fructose Metabolism GLYCEROL METABOLISM%SMPDB%SMP0121309 Glycerol Metabolism GLYCEROL METABOLISM II%PATHWHIZ%PW122618 Glycerol Metabolism II GLYCEROL METABOLISM III (SN-GLYCERO-3-PHOSPHOETHANOLAMINE)%PATHWHIZ%PW122619 Glycerol Metabolism III (sn-Glycero-3-Phosphoethanolamine) GLYCEROL METABOLISM IV (GLYCEROPHOSPHOGLYCEROL)%SMPDB%SMP0121312 Glycerol Metabolism IV (Glycerophosphoglycerol) GLYCEROL METABOLISM V (GLYCEROPHOSPHOSERINE)%SMPDB%SMP0121313 Glycerol Metabolism V (Glycerophosphoserine)