FATTY ACID BIOSYNTHESIS%WIKIPATHWAYS_20260710%WP504%RATTUS NORVEGICUS Fatty acid biosynthesis Fasn Acsl5 Acsl6 Scd1 Acsl3 Acacb Acaca Hadh Mecr Echdc3 Echdc1 Echdc2 Decr1 Acly Echs1 Acaa2 Pc Acsl1 SYNTHESIS AND DEGRADATION OF KETONE BODIES%WIKIPATHWAYS_20260710%WP349%RATTUS NORVEGICUS Synthesis and degradation of ketone bodies Hmgcl Bdh1 Oxct1 Hmgcs2 GLUTATHIONE METABOLISM%WIKIPATHWAYS_20260710%WP469%RATTUS NORVEGICUS Glutathione metabolism Ggt5 Gpx3 Gss Anpep Gstm6 Gstm3 Gstm2 G6pdx Gstt2 Gstt1 Gclm Ggt1 Oplah STEROID BIOSYNTHESIS%WIKIPATHWAYS_20260710%WP66%RATTUS NORVEGICUS Steroid biosynthesis Hsd17b2 F13b Cyp17a1 Hsd3b6 Hsd17b7 Hsd3b5 Hsd17b3 Hsd3b1 Hsd17b4 Hsd17b1 FATTY ACID OMEGA OXIDATION%WIKIPATHWAYS_20260710%WP133%RATTUS NORVEGICUS Fatty acid omega oxidation Adh4 Aldh1a1 Adh1 Cyp2e1 Aldh2 Cyp1a1 Cyp4a2 Cyp3a2 Adh7 Adh6 Acad10 Adh5 GPCRS OTHER%WIKIPATHWAYS_20260710%WP409%RATTUS NORVEGICUS GPCRs other Prokr2 Adora2a Adgrg1 Cxcr1 Ednra Gnrhr Ntsr1 Grm1 Htr7 Fshr Grm8 Htr2a Gpr61 Or1n1 Ccr5 Ccr2 Gpr176 Adra1d Cckbr Alg6 Adgrl2 Adgrl3 Gpr135 Sstr2 Smo Htr1f Taar3 Rxfp3 Taar2 Rxfp1 Taar5 Ghrhr Gpr183 C5ar2 F2r Or3a1e Or2a5 Chrm3 Ptgfr Chrm2 Hrh4 Gpr88 Or2f1 S1pr1 Drd3 Drd4 Celsr2 Cnr1 Gpr18 Grpr Uts2r P2ry13 Gpr17 Ltb4r2 Lgr6 Or10a2 BURN WOUND HEALING%WIKIPATHWAYS_20260710%WP5057%RATTUS NORVEGICUS Burn wound healing Il10 Adora2b Epo Dll4 Pdgfa Arfgap1 Ccn2 Tp53 Acta1 Jun Col1a1 Syk Casp3 Col4a1 Chp1 Ankrd1 Igf1 Syp Mmp9 Ptgis Il1rl1 Glb1 Il1b Cdc25b Gpr176 ACE INHIBITOR PATHWAY%WIKIPATHWAYS_20260710%WP557%RATTUS NORVEGICUS ACE inhibitor pathway Ace Nos3 Agtr1b Kng2l1 Agtr2 Bdkrb2 Kng2 Agt Ren1 ESTROGEN METABOLISM%WIKIPATHWAYS_20260710%WP1302%RATTUS NORVEGICUS Estrogen metabolism Sult1e1 Cyp1a1 Nqo1 Gstm1 Comt Sult1a1 Arsl Cyp1b1 REGULATION OF ACTIN CYTOSKELETON%WIKIPATHWAYS_20260710%WP351%RATTUS NORVEGICUS Regulation of actin cytoskeleton F2r Chrm3 Chrm2 Pdgfa Ins1 Ins2 Mapk1 Fgf2 Fgf1 Fgf4 Mapk3 Fgf3 Mapk4 Fgf6 Fgf5 Fgf8 Fgf7 Fgf9 Cfl1 Cfl2 Egfr Actb Nras Pip4k2b Pfn1 Ezr Raf1 Vcl Pip4k2a Arhgef7 Arhgef6 Arhgef1 Pxn Myh10 Chrm1 Nckap1 Chrm5 Chrm4 Pdgfrb Itga1 Pdgfra Rras2 Pik3cg Slc9a1 Actg1 Pik3cd Pik3ca Pik3c2b Pik3c2a Ssh3 Fgfr3 Pik3c2g Ptk2 Ssh2 Fgfr4 Ssh1 Fgfr1 Fgfr2 Mylk Arpc5 Cd14 Fgf16 Fgf17 Fgf14 Fgf18 Fgf19 Braf Fgf12 Fgf13 Pik3c3 Fgf10 Rhoa Fgf11 Enah Rac1 Baiap2 Git1 Fgf20 F2 Fgf23 Rras Pik3r5 Rassf7 Sos2 Pik3r1 Crk Sos1 Pik3r2 Pik3r3 Gna12 Gna13 Dock1 Fgd1 Bcar1 Pak1 Pak6 Csk Pak3 Pak2 Pak5 Pak4 Cdc42 Tmsb4x Arhgap35 Wasf2 Gsn Wasf1 Egf Mos Map2k1 Apc Limk1 Rock1 Pip5k1b Pip5k1a INTRACELLULAR TRAFFICKING OF CFTR%WIKIPATHWAYS_20260710%WP1486%RATTUS NORVEGICUS Intracellular trafficking of CFTR Fblim1 Rab7a Rab11a Ezr Cftr Nherf1 ADIPOGENESIS%WIKIPATHWAYS_20260710%WP155%RATTUS NORVEGICUS Adipogenesis Nr3c1 Lpl Gh1 Il6 Tgfb1 Hif1a Dvl1 Id3 Gtf3a Ndn Cisd1 Pck1 Pck2 Egr2 Lif Bmp4 Bmp3 Wwtr1 Stat5a Bmp2 Stat5b Bmp1 Lipe Hnf1a Hmga1 Plin2 Adipoq Necab3 Epas1 Rara Slc2a4 Foxo1 Sfrp4 Nr2f1 Ppard Ppara Pparg Rbl2 Rbl1 Klf15 Ncor1 Il6st Ucp1 Gadd45b Gadd45a Pnpla3 Cebpd Mef2d Cebpb Ncoa2 Zmpste24 Ncoa1 Rb1 Asip Osm Lpin3 Ppargc1a Celf1 Lpin1 Dlk1 Mixl1 Mef2a Mef2b Mef2c Klf5 Lep Spock1 Stat3 E2f1 Fas Cdkn1a Gdf10 Agpat2 Srebf1 Igf1 Ptgis Agt Ins2 Socs3 Scd1 Nampt Nrip1 Trib3 Ahr Irs2 Tnf Lifr Prlr Bscl2 Cyp26b1 Foxc2 Wnt5b Twist1 Nr1h3 Ebf1 Mif Retn Rxra Cyp26a1 Mbnl1 Frzb Cntfr Gata3 Serpine1 Gata4 Rxrg Gata2 Cfd BETA OXIDATION META PATHWAY%WIKIPATHWAYS_20260710%WP372%RATTUS NORVEGICUS Beta oxidation meta pathway Lpl Acsl5 Acsl6 Acsl3 Hadh Hadha Hadhb Gcdh Crat Tpi1 Acadm Cpt2 Acads Pnpla2 Acadvl Cpt1a Gpd2 Lipe Lipf Acsl4 Dld Acat1 Echs1 Acsl1 FOLIC ACID NETWORK%WIKIPATHWAYS_20260710%WP1311%RATTUS NORVEGICUS Folic acid network Mtr Selenow Kmo Sod1 Ptgds Txnrd2 Cbs Cat Pnpo Xdh Mt-co2 Mthfr Selenok Gpx3 Fads2 Ptgis Mt-co1 Gpx1 Gpx6 Alox5 Msrb1 S1P RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260710%WP1312%RATTUS NORVEGICUS S1P receptor signal transduction Smpd2 Mapk12 Plcb3 Plcb2 Mapk1 Plcb1 Asah1 Sphk2 Akt3 Mapk3 Akt2 Sphk1 Mapk4 Akt1 Gnai1 S1pr3 Pik3c2b S1pr1 Gnai3 TCA CYCLE%WIKIPATHWAYS_20260710%WP347%RATTUS NORVEGICUS TCA cycle Sdhb Sdha Idh3b Afdn Pdha1 Suclg1 Suclg2 Pdk4 Pdk3 Ogdh Pdk2 Dld Fh Mdh1 Mdh2 Pdhb Pc Sdhc AFLATOXIN B1 METABOLISM%WIKIPATHWAYS_20260710%WP1300%RATTUS NORVEGICUS Aflatoxin B1 metabolism Gstm1 Akr7a3 Akr7a2 Ephx1 GPCRS CLASS C METABOTROPIC GLUTAMATE PHEROMONE%WIKIPATHWAYS_20260710%WP42%RATTUS NORVEGICUS GPCRs class C metabotropic glutamate pheromone Gprc5b Gprc5a Casr Gprc5d Gprc5c Grm3 Grm2 Grm5 Grm1 Grm4 Grm7 Gabbr1 Grm6 Grm8 Gabbr2 RENIN ANGIOTENSIN SYSTEM%WIKIPATHWAYS_20260710%WP376%RATTUS NORVEGICUS Renin angiotensin system Raf1 Pik3ca Mapk9 Atf2 Ikbkb Mapk8 Ctsg Ptk2 Ikbkg Elk1 Jak2 Cpa3 Mme Agtr1 Prkaca Prkcq Fos Rela Ace2 Ptgir Enpep Map3k1 Ctsa Shc1 Map2k7 Nln Cma1 Lnpep Mapk13 Rac1 Ptk2b Map2k4 Mas1 Grb2 Itpr3 Itpr2 Mapk10 Itpr1 Stat3 Pak1 Pak6 Pak3 Pak2 Pak5 Pak4 Jun Ren1 Ace Agtr2 Agt Anpep Mapk1 Plcb1 Mapk3 LIPID DROPLET METABOLISM%WIKIPATHWAYS_20260710%WP3901%RATTUS NORVEGICUS Lipid droplet metabolism Gpat2 Dgat2 Agpat5 Dgat1 Acsl3 Agpat3 Fitm2 Agpat4 Agpat1 Agpat2 Bscl2 Pnpla2 Gpd2 Lpin3 Plin2 Lpin1 Soat1 Aup1 Lipa Acsl1 APOPTOSIS MODULATION BY HSP70%WIKIPATHWAYS_20260710%WP487%RATTUS NORVEGICUS Apoptosis modulation by HSP70 Fas Casp7 Casp9 Cycs Casp6 Aifm1 Hspa1b Map3k1 Casp2 Ripk1 Tnfrsf1a Nfkb1 Fadd Casp3 Faslg Bid Mapk10 IL 5 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP44%RATTUS NORVEGICUS IL 5 signaling pathway Raf1 Stat5a Stat5b Pik3cg Mapk9 Atf2 Elk1 Jak2 Shc1 Rac1 Ptk2b Grb2 Pik3r1 Pik3r2 Stat3 Jun Nfkb1 Syk Rap1gap Pla2g4a Ctnnb1 Crkl Itgam Pim1 Foxo3 Jak1 Sox4 Alox5 Sdcbp Alox5ap Hcls1 Gsk3b Hck Gsk3a Prkcb Rps6ka1 Itgb2 Prkcd Il5ra Btk Shc2 Unc119 Ptpn6 Il5 Ptpn11 Lyn Mapk14 Mapk1 Sh2b2 Nfkbia Rapgef1 Bax Mapk3 Cdkn1b Hras Akt1 MRNA PROCESSING%WIKIPATHWAYS_20260710%WP529%RATTUS NORVEGICUS mRNA processing Rnmt Snrnp70 Clp1 Snrpb2 Xrn2 Spop Prpf8 Snrnp40 Prpf18 Hnrnpr Dhx9 Hnrnpu Papola Snrpb Snrpa1 Snrpa Clk2 Clk3 Clk4 Mettl3 Prp4k Ptbp1 Fus Sugp1 Sugp2 Srpk1 Cpsf4 Cpsf1 Hnrnpd Cpsf2 Cpsf3 Ddx1 Snrpepl2 Hnrnpk Hnrnpm Hnrnpab Cstf1 Ybx1 Clasrp Nudt21 Tmed10 Sfpq Prmt1 Prmt2 Cstf2 Dhx16 Cstf3 Srsf1 Ptbp2 Srsf9 Srsf7 Srsf6 Srsf5 Srsf4 Srsf3 Srsf2 Srek1 Srsf10 Celf1 Srrm1 Rbm17 U2af1 Nxf1 Sf3a1 Sf3a2 Sf3a3 U2af2 Ncbp2 Ncbp1 Cd2bp2 Rbmx Snrpd1 Tra2b Celf4 Celf2 Pabpn1 Snrpd3 Sf3b2 Sf3b3 Sf3b4 Rbm39 Sfswap Sf3b5 Srp54 Hnrnph2 Ppm1g Hnrnph1 Dicer1 Ddx20 Rngtt Smc1a Prpf4 Phf5a Prpf6 Prpf3 Prpf40a Scamp3 Hnrnpa2b1 Supt5h Cdc40 PROSTAGLANDIN SYNTHESIS AND REGULATION%WIKIPATHWAYS_20260710%WP303%RATTUS NORVEGICUS Prostaglandin synthesis and regulation Ednra Pla2g4a Ednrb Ptgis Anxa8 Anxa6 Prl Ptgdr Ptger4 Ptger2 Ptger3 Cyp11a1 Ptger1 Ptgds S100a6 Scgb1a1 Hsd11b1 Hsd11b2 Tbxas1 Edn1 Hpgd Ptgir Anxa5 Anxa4 Anxa3 S100a10 Ptgs1 Anxa1 Ptgs2 Ptgfr HYPOTHETICAL NETWORK FOR DRUG ADDICTION%WIKIPATHWAYS_20260710%WP1281%RATTUS NORVEGICUS Hypothetical network for drug addiction Grin2c Grin2b Prkaca Acta1 Mapk1 Grin2a Nisch Camk4 Krit1 Mapk3 Grm5 Terf2ip Grm1 Gria2 Camk2b Map2k1 Gria1 Ppa1 Prkce Drd1 Drd4 Grin1 Grin2d Adcy8 TRYPTOPHAN METABOLISM%WIKIPATHWAYS_20260710%WP270%RATTUS NORVEGICUS Tryptophan metabolism Ddc Tph1 Aldh1a1 Aldh3a2 Aldh9a1 Inmt Cyp2e1 Aldh2 Cyp2j3 Hsd17b10 Cyp1a1 Cyp2b15 Ogdh Wars1 Cyp2j4 Tdo2 Gcdh Acad10 Cyp4f1 Cyp2f2 Aadat Cyp7b1 Aanat Afmid Aoc1 Dhcr24 Haao Asmt Cyp2d26 Kynu Mdm2 Cyp2a2 Cyp2a1 Echs1 Ube3a Acmsd Ido1 Cat Hadh Prmt1 Cyp1b1 HEXOSES METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260710%WP3916%RATTUS NORVEGICUS Hexoses metabolism in proximal tubules Pdha1 Pdk4 Pdk3 Pdk2 Pck1 Gpi Pdhx Psme3 Slc5a10 Sord Eno1 Eno3 Eno2 Khk Mpc1 Mpc2 Pgam2 Slc2a2 Pgam1 Akr1b1 Slc2a5 Pdk1 Gapdh Tkfc Ldha Ldhb Fbp1 Pklr Aldob Aldoc Aldoa Pfkl Pgk1 Slc5a1 Slc5a2 Pfkp Slc5a9 Got1 Got2 G6pc1 Hk1 Pdp1 Pdp2 Tpi1 Dld Acly Pc Mdh1 Mdh2 Pdhb METHYLATION%WIKIPATHWAYS_20260710%WP1282%RATTUS NORVEGICUS Methylation Pnmt Mat2a Inmt Mat1a Hnmt Comt COMPLEMENT AND COAGULATION CASCADES%WIKIPATHWAYS_20260710%WP547%RATTUS NORVEGICUS Complement and coagulation cascades F13b F2r F2 Cr2 Serping1 Cr1l C3ar1 Serpinf2 Mbl1 Fgb Vwf Masp1 Masp2 Tfpi C8b F3 F7 F8 F9 Plaur Cfb C1qb C1qa Cd59b Cfh Cfi Plg Klkb1 C2 Kng2l1 Proc C4 C6 Kng2 C9 Serpind1 Cd46 F10 C1s C1r F12 Plat Thbd Plau Pros1 Serpinc1 A2m Cpb2 Cd55 C1qc Serpine1 Cfd SPINAL CORD INJURY%WIKIPATHWAYS_20260710%WP2433%RATTUS NORVEGICUS Spinal cord injury Rgma Vcan Gja1 Ifng Il6 Sema6a Tgfb1 Lilrb2 Nos1 Sox9 Tnfsf13b Zfp36 Gap43 Arg1 Prpg2 Omg Plxna2 Epha4 Mag Rtn4r Tacr1 Prkca Tlr4 Ngfr Cxcl10 Pla2g2a Ccng1 Ntn1 Klk8 Necab3 Il2 Rtn4 Gfap Il4 Selp Bcan Tnfsf13 C5 Gdnf Ccl2 Pla2g5 Mbp Cd47 Fos Cxcl1 Cxcl2 Pla2g6 Ppp3ca Gadd45a Fcgr2a Egr1 Ccnd1 Nos2 Ptpra Ncan Acan Il1a Rb1 Xylt1 Nox4 Cdk1 Rock2 Il1r1 Vim E2f5 E2f1 Tp53 Casp3 Col4a1 Mmp9 Il1b Anxa1 Mapk1 Mapk3 Btg2 Chst11 Bdnf Fkbp1a Ptprz1 Slit1 Slit2 Aqp4 Grin1 Slit3 Pdyn MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP358%RATTUS NORVEGICUS MAPK signaling pathway Tgfb1 Prkca Ppp3ca Gadd45a Il1a Il1r1 Cacng8 Cacna1g Cacna1h Cacna1e Cacng7 Mef2c Cacna1f Cacna1c Cacna1d Cacna1a Cacna1b Cacng1 Fas Map3k8 Map3k7 Cacng4 Map3k6 Cacng5 Map3k5 Pdgfa Cacng3 Map3k4 Elk4 Tp53 Cacna1s Map3k20 Jun Lamtor3 Map3k2 Prkcg Casp3 Flna Rasgrp3 Rasgrp4 Rasgrp1 Flnc Rasgrp2 Flnb Jund Rasa1 Stmn1 Il1b Cdc25b Nlk Stk4 Map4k3 Tgfb2 Tgfb3 Nf1 Hspb1 Tmem97 Ppp3cc Ppp3cb Map4k2 Map4k1 Rasgrf2 Tab2 Daxx Ppp5c Pla2g4b Traf6 Pla2g4e Mapk1 Pla2g4d Fgf2 Nfkb2 Fgf1 Traf2 Fgf4 Akt3 Nfatc1 Mapk3 Akt2 Mapt Fgf3 Nfatc3 Akt1 Rap1a Fgf6 Prkacb Fgf5 Ngf Fgf8 Rps6ka3 Fgf7 Rps6ka4 Fgf9 Cacna2d1 Cacna2d3 Cacna2d4 Egfr Dusp16 Ppm1b Nras Ptpn7 Map2k6 Ptpn5 Dusp3 Raf1 Ntf4 Dusp2 Hspa1l Dusp4 Ntf3 Arrb2 Arrb1 Dusp10 Dusp9 Dusp8 Cacnb4 Cacnb1 Pdgfrb Mapkapk2 Cacnb2 Taok2 Rras2 Taok1 Taok3 Mapkapk5 Ntrk2 Ntrk1 Rapgef2 Mapk8ip1 Mapk9 Mapk8ip3 Atf2 Il1r2 Fgfr3 Ikbkb Mknk1 Mapk8 Chuk Map3k11 Ikbkg Tgfbr1 Elk1 Fgfr4 Map3k14 Fgfr1 Fgfr2 Prkaca Cd14 Fgf16 Fos Rela Fgf17 Fgf14 Fgf18 Fgf19 Map3k1 Braf Fgf12 Fgf13 Map2k7 Fgf10 Fgf11 Mapk13 Rac1 Map2k4 Grb2 Fgf20 Rras Mapk10 Sos2 Crk Sos1 Gna12 Pak1 Pak2 Tnfrsf1a Cdc42 Nfkb1 Faslg Pla2g4a Egf Mos Crkl Map2k1 Prkcd Mapk14 Hras Bdnf TYPE II INTERFERON SIGNALING IFNG %WIKIPATHWAYS_20260710%WP1289%RATTUS NORVEGICUS Type II interferon signaling IFNG Ifng Cxcl10 Jak1 Il1b Spi1 Jak2 Socs3 Eif2ak2 Cxcl9 Ifnb1 Ifngr2 Oas1a Prkcd Ifngr1 Reg1 Psmb9 Gbp1 Hist1h4m Tap1 Ptpn11 Ciita Nos2 Irf4 Cybb Irf1 Irf2 Irf8 Isg15 Irf9 Ifit2 METAPATHWAY BIOTRANSFORMATION%WIKIPATHWAYS_20260710%WP1286%RATTUS NORVEGICUS Metapathway biotransformation Gal3st3 Nat9 Cyp17a1 Inmt Cyp2e1 Cyp1a1 Akr7a3 Akr7a2 Ephx1 Cyp2f2 Cyp7b1 Akr1b1 Chst10 Chst12 Sult2b1 Cyp2u1 Chst13 Cyp4f18 Chst14 Cyp4f17 Sult6b2 Gstk1 Naa40 Ugt2b1 Gsto1 Nat10 Mgst1 Ndst1 Cyp4x1 Ndst3 Hnmt Hs3st3a1 Sult4a1 Chst1 Sult2a1 Chst3 Sult2a6 Chst4 Chst6 Cyp24a1 Chst9 Akr1c1 Gstp1 Cyp7a1 Zfp628 Gstz1 Hs3st2 Sult1b1 Hs3st5 Hs3st6 Cyp2s1 Hs3st3b1 Gstm7 Cyp4f39 Baat Gstm5 Gstm4 Cyp27b1 Naa20 Akr1d1 Gstcd Kcnab2 Cyp51a1 Sult1e1 Glyat Gstm1 Cyp8b1 Comt Kcnab3 Hs2st1 Sult1a1 Cyp26b1 Tpmt Cyp1b1 Gss Fmo1 Fmo3 Fmo2 Fmo5 Hs6st3 Fmo4 Hs6st1 Naa50 Cyp26a1 Akr1b10 Chst11 Cyp26c1 Cyp46a1 Nat8 Nat1 Cyp21a1 Nat2 Ephx2 Gal3st4 Akr1a1 EPO RECEPTOR SIGNALING%WIKIPATHWAYS_20260710%WP1284%RATTUS NORVEGICUS EPO receptor signaling Sos1 Ptprc Jak2 Src Stat3 Map2k2 Ptpru Raf1 Irs2 Epo Shc1 Pdk1 Mapk1 Stat5a Stat5b Mapk3 Pik3cg Akt1 Map2k1 Grb2 Rasa1 GLUCOCORTICOID METABOLISM%WIKIPATHWAYS_20260710%WP305%RATTUS NORVEGICUS Glucocorticoid metabolism Cyp11a1 Cyp17a1 Akr1c9 Hsd11b1 Hsd11b2 Cyp21a1 POLYOL PATHWAY%WIKIPATHWAYS_20260710%WP1303%RATTUS NORVEGICUS Polyol pathway Sord Aldob Khk Akr1b1 BRAIN DERIVED NEUROTROPHIC FACTOR%WIKIPATHWAYS_20260710%WP2148%RATTUS NORVEGICUS Brain derived neurotrophic factor Plg Mapk1 Ngfr Raf1 Ntrk2 Map2k1 Bdnf Serpine1 Plat GPCRS CLASS A RHODOPSIN LIKE%WIKIPATHWAYS_20260710%WP473%RATTUS NORVEGICUS GPCRs class A rhodopsin like Hcar1 Adra2a Ghsr Adra2c Adra2b Gpr161 Npy1r Rrh Htr4 Adora2a Or3a1 Htr6 Cxcr1 Oprd1 Ednra Or2h2 Gpr65 Or2h1 Ntsr1 Gpr68 Htr7 Cxcr4 Gpr63 Fshr Oprl1 Adrb1 Htr2a Gpr173 Adra1b Gpr174 Ccr5 Adra1a Ccr2 Adrb3 Galr2 Adra1d Gpr171 Cckbr Galr3 Galr1 Cmklr1 Lhcgr Sstr5 Sstr2 Sstr4 Sstr3 Htr1f Olr226 Sstr1 Avpr1b Mc5r Oprm1 Gpr75 Htr5a Tbxa2r C5ar2 Or7c70 F2r Ffar3 Or3a1e Fpr1 Aplnr Chrm3 Nmbr Ptgfr Fpr3 Chrm2 Ffar1 Bdkrb1 Fpr2 Or2f1 Ffar2 Ccr10 Drd3 Hrh1 Drd4 Or2b2 Or2j3 Cnr1 Hrh2 Gpr18 Hrh3 Grpr Or5v1b Gpr85 P2ry13 Or7a36 Gpr17 Drd5 Opn4 Lpar6 Oxtr Adora2b Xcr1 Lpar5 Opn3 Olr1073 Gper1 Gpr19 Sucnr1 Or6b1 Gpr15 Or2c1 Or13c7d Adora1 Gpr12 Adora3 Or2t1 Cckar Opn1sw Npbwr1 Ednrb Nmur2 Prlhr Npy5r Ntsr2 Ptgdr Brs3 Gpr25 Ptger4 Mc2r Ptger2 Gpr27 Ptger3 Gpr22 Gpr21 Ptger1 Ccr9 Agtr2 Bdkrb2 Mchr1 Ccr7 Htr2c Ccr6 Lpar4 Ccr3 Mtnr1a Npy4r Gpr37 Gpr39 Htr1d Or11a4 Htr1a Rgr Or14j1 Mc4r P2ry6 Or10j27 Ptafr Npffr1 P2ry2 Or2f2 Npffr2 Drd1 P2ry1 Ptgdr2 Rho Hcrtr1 Or5ap2b Or2w1 Gpr37l1 Cysltr2 Cysltr1 Npy2r Ackr4 Gpr4 Cnr2 Gpr3 Ackr2 Gpr6 P2ry10 Chrm1 Mc3r Or2ag1 Chrm5 P2ry12 Chrm4 P2ry14 F2rl1 Or10a4 Gpr50 Oprk1 F2rl2 F2rl3 Agtr1 Ptgir Mas1 C3ar1 NUCLEAR RECEPTORS IN LIPID METABOLISM AND TOXICITY%WIKIPATHWAYS_20260710%WP139%RATTUS NORVEGICUS Nuclear receptors in lipid metabolism and toxicity Cyp2e1 Cyp24a1 Cyp7a1 Nr1i3 Nr1i2 Abcb1a Abcd2 Abcd3 Cyp2c11 Abcb4 Rara Cyp4b1 Rarb Cyp2b2 Vdr Ppard Abcg1 Cyp27b1 Ppara Abca1 Pparg Abcc3 Abcg5 Abcc2 Abcb11 Cyp8b1 Nr1h3 Cyp26a1 KIT RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP147%RATTUS NORVEGICUS Kit receptor signaling pathway Src Ptpru Raf1 Stat5a Prkca Stat5b Pik3cg Jak2 Stap1 Mitf Grb10 Socs5 Socs4 Matk Socs6 Csf2rb Shc1 Cltc Sh3kbp1 Plcg1 Cblb Vav2 Fgr Dok1 Kit Tnfrsf10b Grb2 Spred1 Mpdz Spred2 Grb7 Abl1 Fyn Pik3r1 Grap Crk Bad Sos1 Plce1 Pik3r2 Tec Fes Stat3 Crkl Map2k1 Rasa1 Hck Prkcb Rps6ka1 Btk Ptpn6 Ptpn11 Lyn Mapk1 Sh2b2 Hras Akt1 INFLAMMATORY RESPONSE PATHWAY%WIKIPATHWAYS_20260710%WP40%RATTUS NORVEGICUS Inflammatory response pathway Ifng Col1a2 Cd86 Cd40 Il4r Cd80 Il5ra Cxhxorf65 Il2ra Il2rb Tnfrsf1b Lama5 Il5 Vtn Il2rg Tnfrsf1a Lck Col1a1 Cd40lg Lamc1 Lamb1 Thbs1 Il2 Il4 TRANSCRIPTIONAL ACTIVATION BY NFE2L2 IN RESPONSE TO PHYTOCHEMICALS%WIKIPATHWAYS_20260710%WP1280%RATTUS NORVEGICUS Transcriptional activation by Nfe2l2 in response to phytochemicals Cebpb Prkca Aimp2 Maf Gclm Hmox1 Nfe2l2 Nqo1 Ephb2 Mapk8 RETINOL METABOLISM%WIKIPATHWAYS_20260710%WP1297%RATTUS NORVEGICUS Retinol metabolism Lpl Adh4 Aldh1a1 Adh1 Cyp2e1 Adh5 Dhrs3 Cd36l1 Rdh12 Aldh1a3 Rara Rdh10 Rarb Bco1 Npc1l1 Rpe65 Rxrb Rbp7 Abcg8 Abcg5 Rbp4 Scarb1 Retsat Crabp2 Cd36 Lrat Rlbp1 Sult1a1 Cyp26b1 Rxra Cyp26a1 Sult2b1 Rxrg PROTEASOME DEGRADATION%WIKIPATHWAYS_20260710%WP302%RATTUS NORVEGICUS Proteasome degradation Psmb7 Psmd8 Uchl1 Psmb1 Psmd3 Psmd2 Psmd5 Psmd4 Psmb2 Ube2d3 Ube2d1 Psmb9 Psmc6 Psmc5 Psma5 Psmc2 Rpn2 Psma2 Psmc4 Psmc3 Rpn1 Psme2 Psme1 Psmd12 Psmd11 Ube2b Psmd13 Uchl3 Psmb8 Psmb6l1 Psmb5 Psmd6 EBV LMP1 SIGNALING%WIKIPATHWAYS_20260710%WP1278%RATTUS NORVEGICUS EBV LMP1 signaling Map3k14 Ifnb1 Map3k7 Rela Pdlim7 Ccl5 Tradd Traf6 Mapk1 Nfkb1 Nfkb2 Ikbkb Mapk8 Chuk MYOMETRIAL RELAXATION AND CONTRACTION PATHWAYS%WIKIPATHWAYS_20260710%WP140%RATTUS NORVEGICUS Myometrial relaxation and contraction pathways Gja1 Il6 Nos1 Prkd1 Ets2 Rgs4 Rgs5 Rgs2 Rgs3 Prkca Rgs1 Crcp Slc8a1 Rgs9 Rgs6 Rgs7 Plcg2 Myl4 Mylk2 Prkch Myl2 Rxfp2 Atf5 Atf3 Maff Pkib Calca Grk5 Grk4 Atf6b Gnaq Pkia Grk6 Prkcz Rxfp1 Pkig Gngt1 Gucy1a1 Dgkz Gnb2 Gnb1 Gnb4 Gnb3 Rln1 Gng13 Ryr2 Atp2a3 Atp2a2 Ywhaq Oxt Adm Ywhah Ywhag Gabpa Ywhae Ywhab Adcy3 Adcy4 Adcy2 Guca2b Adcy7 Guca2a Oxtr Crhr1 Adcy5 Lpar1 Creb3 Adcy9 Cald1 Pde4b Crh Acta1 Prkar1a Jun Prkar1b Rgs20 Camk2g Prkcg Rgs17 Camk2d Igfbp3 Gng3 Rgs19 Gng2 Igfbp4 Vkorc1l1 Camk2a Rgs14 Gng7 Il1b Igfbp1 Rgs16 Pde4d Gng8 Nos3 Actc1 Prkar2b Rgs10 Ackr5 Corin Ramp3 Plcb3 Prkacb Camk2b Prkce Actb Arrb2 Arrb1 Actg1 Atf2 Prkcq Fos Plcg1 Itpr3 Itpr1 Gsto1 Nfkb1 Prkcb Prkcd NUCLEOTIDE METABOLISM%WIKIPATHWAYS_20260710%WP146%RATTUS NORVEGICUS Nucleotide metabolism Polg Adss2 Sat1 Srm Dhfr Pold1 Prps2 Polb Impdh1 Nme2 Mthfd2 Hprt1 NUCLEOTIDE GPCRS%WIKIPATHWAYS_20260710%WP502%RATTUS NORVEGICUS Nucleotide GPCRs Adora2a Adora1 P2ry6 Lpar6 Adora2b P2ry2 Lpar4 P2ry1 IL 9 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP8%RATTUS NORVEGICUS IL 9 signaling pathway Socs3 Stat3 Irs2 Cxhxorf65 Ptpn11 Shc1 Il2rg Mapk1 Stat5a Vcp Stat5b Mapk3 Kat5 Il9 Akt1 Jak3 Map2k1 Grb2 Il9r Jak1 Pik3r1 INTERACTIONS BETWEEN CFTR AND OTHER ION CHANNELS%WIKIPATHWAYS_20260710%WP1485%RATTUS NORVEGICUS Interactions between CFTR and other ion channels Scnn1b Scnn1g Cftr Nherf1 P38 MAPK SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP294%RATTUS NORVEGICUS p38 Mapk signaling pathway Map2k6 Map3k7 Map3k5 Tradd Ripk1 Cdc42 Mapkapk2 Pla2g4a Mapkapk5 Atf2 Mknk1 Tgfbr1 Elk1 Tgfb2 Hspb1 Daxx Map3k1 Shc1 Mef2d Mapk14 Traf2 Rac1 Map2k4 Hras Grb2 Max Map3k9 Rps6ka5 CFTR ACTIVITY IN THE PLASMA MEMBRANE%WIKIPATHWAYS_20260710%WP1488%RATTUS NORVEGICUS CFTR activity in the plasma membrane Rack1 Nherf2 Prkaa2 Snap23 Pdzk1 Ezr Prkaca Plcb3 Plcb2 Plcb1 Prkcg Cftr Ppp2ca Plcz1 Nherf1 TOLL LIKE RECEPTOR SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP1309%RATTUS NORVEGICUS Toll like receptor signaling pathway Map2k6 Il6 Il12b Il12a Ticam2 Lbp Ly96 Tlr1 Ifna4 Irf3 Ccl5 Ifna1 Irf7 Tlr8 Irf5 Tlr7 Tlr6 Tlr5 Tlr4 Tlr3 Tlr2 Pik3cg Cxcl11 Cxcl10 Ifnar1 Ccl4 Pik3cd Ccl3 Pik3ca Spp1 Mapk9 Tollip Map2k3 Ikbkb Mapk8 Chuk Ikbkg Cxcl9 Ifnb1 Cd14 Fos Rela Map2k7 Mapk13 Rac1 Map2k4 Mapk10 Pik3r5 Pik3r1 Pik3r2 Pik3r3 Cd86 Map3k8 Cd40 Map3k7 Cd80 Ripk1 Jun Nfkb1 Fadd Map2k1 Il1b Tnf Tab2 Traf6 Mapk14 Mapk1 Nfkb2 Nfkbia Akt3 Mapk3 Akt2 Akt1 ANGIOTENSIN II SIGNALING ACUTE IN THICK ASCENDING LIMBS%WIKIPATHWAYS_20260710%WP3887%RATTUS NORVEGICUS Angiotensin II signaling acute in thick ascending limbs Arrb2 Prkcg Prkca Plcg2 Calm3 Calm2 Pdpk1 Pde2a Nos3 Pten Agtr1b Dnm1 Agtrap Agtr2 Agtr1 Prkaca Gnaq Plcg1 Akt3 Akt2 Nox4 Akt1 Mas1 Itpr3 Itpr2 Itpr1 SELENIUM METABOLISM SELENOPROTEINS%WIKIPATHWAYS_20260710%WP1293%RATTUS NORVEGICUS Selenium metabolism selenoproteins Jun Nfkb1 Nfe2l2 Gpx6 Msrb1 Selenow Selenbp1 Txnrd2 Rpl30 Eefsec Crem Sp3 Fos Selenof Rela Sars2 Selenoi Sars1 Selenok Fabp1 Gpx3 Selenoo Selenop Selenos Dio1 Selenot Dio2 Dio3 Selenov Sephs1 Trnau1ap OXIDATIVE STRESS RESPONSE%WIKIPATHWAYS_20260710%WP173%RATTUS NORVEGICUS Oxidative stress response Sod1 Txnrd2 Mgst1 Cat Fos Cyp1a1 Nqo1 Xdh Gpx3 Mapk14 Nfkb1 Gstt2 Hmox1 Nfix Sod3 Sod2 Txn2 Mapk10 Cyba Junb ESTROGEN SIGNALING%WIKIPATHWAYS_20260710%WP1279%RATTUS NORVEGICUS Estrogen signaling Src Mapk9 Ikbkb Chuk Elk1 Prkaca Fos Braf Gngt1 Ccnd1 Gnb1 Grb2 Ilk Mnat1 Hdac3 Hdac2 Sos1 Hdac5 Taf13 Hdac1 Taf12 Gtf2f2 Tbp Ccnh Gtf2b Gtf2e1 Polr2c Polr2a Gper1 Polr2b Taf9 Polr2g Polr2h Jun Nfkb1 Polr2f Polr2i Polr2j Gtf2h2 Gtf2h1 Gtf2h4 Gtf2h3 Ercc3 Map2k1 Esr1 Crebbp Cdk7 Brca1 Taf7 Taf6 Taf5 Shc2 Mapk14 Mapk1 Hras Akt1 NOD LIKE RECEPTOR NLR SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP1294%RATTUS NORVEGICUS Nod like receptor NLR signaling pathway Ikbkg Cd40 Map3k7 Ephb2 Rela Ikbkb Mapk8 Chuk BETA OXIDATION OF UNSATURATED FATTY ACIDS%WIKIPATHWAYS_20260710%WP418%RATTUS NORVEGICUS Beta oxidation of unsaturated fatty acids Eci1 Hadha Decr1 Hadhb Acadm AMINO ACID CONJUGATION OF BENZOIC ACID%WIKIPATHWAYS_20260710%WP1287%RATTUS NORVEGICUS Amino acid conjugation of benzoic acid Glyat SEROTONIN AND ANXIETY%WIKIPATHWAYS_20260710%WP2132%RATTUS NORVEGICUS Serotonin and anxiety Nlgn1 Htr1a Arc Plek Prkcb Htr2c Fos Htr2a Ppp3ca Adra1a Crh Grin2d HOMOLOGOUS RECOMBINATION%WIKIPATHWAYS_20260710%WP1296%RATTUS NORVEGICUS Homologous recombination Pold2 Rad51 Rad50 Brca2 Rad52 Pold1 Pold4 Pold3 Fsbp Nbn TRANSLATION FACTORS%WIKIPATHWAYS_20260710%WP149%RATTUS NORVEGICUS Translation factors Eif2b2 Eif2b5 Eif2b4 Kcnq2 Eif2s2 Eef2k Eif2b1 Eif4h Eif4e Eif1 Eif1ax Eif6 Eif4a2 Eif4a1 Etf1 Gspt2 Cluh Eif2ak2 Eef1a2 Eef1d Eif3j Pycr3 Eif2s3 Eif2ak1 Eef1g Eif4ebp2 Eif3f Eif4ebp1 Eif4g1 Eif2ak3 Eif4g3 Eif3b Eif3a Eif1a Eif5b Eif5a Eif2b3 IL 3 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP319%RATTUS NORVEGICUS IL 3 signaling pathway Rack1 Src Raf1 Vcl Pxn Mapk7 Mapkapk2 Birc5 Stat5a Bcl2l11 Prkca Kcnip3 Stat5b Rac2 Slc2a1 Fcer2 Mmp2 Pik3cd Gab1 Pik3ca Bcl2l1 Mapk9 Gab2 Atf2 Chek1 Rara Il3ra Mapk8 Il3 Foxo1 Selp Rps6kb2 Ptk2 Id1 Bmx Spi1 Jak2 Dnm1 Prkaca Matk Csf2rb Shc1 Rac1 Grb2 Ywhaq Fyn Pik3r1 Ywhab Crk Bad Sos1 Pik3r2 Tec Fes Stat3 Pak1 Tnfrsf1b Lck Cdc42 Nfkb1 Syk Crkl Map2k1 Mmp9 Jak1 Gsk3b Hck Socs3 Gsk3a Prkcb Hspb1 Ptpn6 Ptpn11 Lyn Mapk14 Mapk1 Rapgef1 Bax Mapk3 Rxra Hras Akt1 Rap1a Ppp2ca Gata2 MONOAMINE GPCRS%WIKIPATHWAYS_20260710%WP276%RATTUS NORVEGICUS Monoamine GPCRs Drd5 Adra2a Adra2c Adra2b Chrm1 Htr4 Chrm5 Chrm4 Htr6 Htr7 Htr2a Adrb1 Adra1b Adra1a Adrb3 Adra1d Htr5b Htr2c Htr1f Htr1d Htr5a Htr1a Chrm3 Chrm2 Drd3 Hrh1 Drd1 Drd4 Hrh2 P53 SIGNAL PATHWAY%WIKIPATHWAYS_20260710%WP656%RATTUS NORVEGICUS p53 signal pathway Ccnb3 Gadd45g Ccne1 Fas Gtse1 Bbc3 Siah1 Casp9 Perp Pmaip1 Parp1 Rprm Tp53 Casp3 Bax Bid Igfbp3 Cdk1 Igf1 Mdm2 HEPATOCYTE GROWTH FACTOR RECEPTOR SIGNALING%WIKIPATHWAYS_20260710%WP94%RATTUS NORVEGICUS Hepatocyte growth factor receptor signaling Crk Sos1 Src Stat3 Map2k2 Raf1 Dock1 Pak1 Pxn Jun Itga1 Crkl Map2k1 Pik3ca Gab1 Rasa1 Mapk8 Ptk2 Elk1 Pten Fos Map4k1 Rap1b Ptpn11 Hgf Itgb1 Met Mapk1 Rapgef1 Mapk3 Ptk2b Hras Rap1a Grb2 MITOCHONDRIAL GENE EXPRESSION%WIKIPATHWAYS_20260710%WP1301%RATTUS NORVEGICUS Mitochondrial gene expression Ppp3ca Prkar1b Tfb1m Tfb2m Mterf1 Camk4 Nrf1 Ppargc1b Myef2 Esrra Ppargc1a Gabpb2 Tfam Pprc1 Gabpa RELATIONSHIP BETWEEN GLUTATHIONE AND NADPH%WIKIPATHWAYS_20260710%WP2562%RATTUS NORVEGICUS Relationship between glutathione and NADPH Mapk8 Gpi Eno1 Pgam2 Gapdh Pklr Aldoa Pfkl Pgk1 Ftl1 Nnt Fth1 Pgm2 Ugdh Pgm1 Ptgr1 Kif1b Pgd Abcc1 Tfr2 Fas Tkt Cdkn1a Gapdhl6 Rpe Taldo1 Dpep2 Map3k5 Txn Rpia Ugp2 Tp53 Ugt8 Ltc4s Tfrc Gck Pgls Casp3 Dffa Gstp1 Gsn Dffb Alox5 Nqo1 Gss Anpep G6pdx Bax Gclm PENTOSE PHOSPHATE PATHWAY%WIKIPATHWAYS_20260710%WP282%RATTUS NORVEGICUS Pentose phosphate pathway Pgls Kif1b G6pdx Pgd Tkt Rpe Taldo1 Rpia WNT SIGNALING PATHWAY AND PLURIPOTENCY%WIKIPATHWAYS_20260710%WP1288%RATTUS NORVEGICUS Wnt signaling pathway and pluripotency Dvl1 Prkca Mapk9 Ppard Prkcq Prkcz Ccnd1 Rhoa Mapk10 Map3k7 Tp53 Jun Pafah1b1 Ppp2r3a Ctnnb1 Sox2 Ppp2r2c Ppp2r2b Apc Ctbp1 Crebbp Wnt5a Ctbp2 Wnt9b Ppp2cb Nlk Prkci Ptpa Gsk3b Axin1 Axin2 Fbxw2 Prkcb Lef1 Wnt11 Tmem97 Tcf7 Prkcd Lrp6 Nkd2 Lrp5 Wnt6 Wnt3a Dvl2 Dvl3 Wnt7a Wnt5b Wnt2 Plau Tcf7l1 Wnt4 Cd44 Wnt3 Pou5f1 Fosl1 Fzd3 Ccnd2 Fzd2 Fzd4 Fzd9 Prkce Fzd8 Nanog Ppp2r2a Ppp2ca Ppp2r1a Ppm1j VEGFR 3 SIGNALING%WIKIPATHWAYS_20260710%WP1964%RATTUS NORVEGICUS VEGFR 3 signaling Bad Itpkc Nos3 Flt4 Vegfd Vegfc Casp9 Shc1 Mapk1 Plcg1 Mapk3 Pik3cg Akt1 Grb2 TNF ALPHA AND MUCUS PRODUCTION IN LUNG EPYTHELIUM%WIKIPATHWAYS_20260710%WP1487%RATTUS NORVEGICUS TNF alpha and mucus production in lung epythelium Ikbkg Sos1 Il6 Tgfa Muc2 Raf1 Ripk2 Rps6ka2 Tnf Rela Tradd Shc1 Tnfrsf1a Mapk1 Nfkb1 Nfkbia Traf2 Tlr4 Map2k1 Grb2 Ikbkb Chuk Egfr ID SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP397%RATTUS NORVEGICUS ID signaling pathway Id3 Psmd4 Myog Ccna2 Srebf1 Myod1 Id2 Kdr Id4 Elk4 Hes1 Tcf7l2 Bmp6 Lck Cd40lg Nfkb1 Pax2 Smad1 Bmp2 Smad4 Pax8 Tert Egf Smad5 Igf1 Igf1r Myf5 Id1 Elk1 Atf3 Ccne1 Rbl2 Rbl1 Rela Rb1 Ngf PROXIMAL TUBULE TRANSPORTERS%WIKIPATHWAYS_20260710%WP3881%RATTUS NORVEGICUS Proximal tubule transporters Ca2 Nherf2 Ca4 Slc22a8 Atp6v1d Ca14 Atp6v1h Slc20a2 Slc22a6 Car15 Slc26a1 Atp1a1 Fxyd4 Slc22a5 Nherf1 Tctn2 Atp6v0a2 Atp6v0a4 Atp6v1e1 Atp6v1g3 Atp6v0e2 Atp6v0a1 Slc1a1 Atp6v0c Car7 Slc4a4 Slc38a7 Slc34a1 Slc6a19 Slc7a6 Slc7a7 Atp1b1 Slc9a3 Slc9a8 Slc13a3 Slc7a8 Atp6v1a Slc13a1 Slc7a9 Slc34a2 Slc13a2 Atp6v1b2 Atp6v0d2 Atp6v0d1 Atp6v1b1 Slc16a10 Atp6v1g1 OXIDATIVE PHOSPHORYLATION%WIKIPATHWAYS_20260710%WP1283%RATTUS NORVEGICUS Oxidative phosphorylation Ndufab1 Ndufc1 Coxfa4 Ndufc2 Ndufa5 Gzmb Atp5pb Gzmc Ndufa9 Ndufa8 Atp5pf Ndufb10 Atp5po Ndufs2 Ndufs5 Ndufs4 Ndufs6 Mt-co3 Ndufs8 Mt-nd5 Adck2 Mt-nd4 Ndufb2 Mt-atp6 Mt-nd6 Atp5mc1 Mt-nd1 Mt-nd3 Mt-nd4l Mt-nd2 Ndufb8 Ndufb7 Atp5mc3 Atp5mf Atp5me Ndufv1 Ndufv3 Atp5f1a Ndufa10l1 MISMATCH REPAIR%WIKIPATHWAYS_20260710%WP1295%RATTUS NORVEGICUS Mismatch repair Rfc1 Pold1 Lig1 Pcna Msh2 IL 1 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP355%RATTUS NORVEGICUS IL 1 signaling pathway Map3k7 Nfkb1 Map2k1 Tollip Il1r2 Il1b Mapk8 Chuk Map3k14 Rela Prkcz Ptpn11 Traf6 Mapk1 Il1rap Peli1 Plcg1 Nfkbia Sqstm1 Il1a Irak4 Mapk3 Irak3 Nfkbib Akt1 Irak2 Capn1 Il1r1 Elp1 Sirpa Capns1 Tab1 Il1rn CHOLESTEROL METABOLISM%WIKIPATHWAYS_20260710%WP632%RATTUS NORVEGICUS Cholesterol metabolism Mvk Rusc1 Lpl Apoc1 Apoc2 Dhcr7 Fdft1 Lss Scarb1 Hmgcs1 Hmgcr Apoe Srebf1 Mvd Msmo1 Soat1 Fdps Idi1 ACETATE MEDIATED PROMOTION OF METABOLIC SYNDROME%WIKIPATHWAYS_20260710%WP3650%RATTUS NORVEGICUS Acetate mediated promotion of metabolic syndrome Ins2 Gast GLYCOGEN METABOLISM%WIKIPATHWAYS_20260710%WP160%RATTUS NORVEGICUS Glycogen metabolism Pgm1 Gbe1 Ugp2 Phkb Ppp2r5b Ppp2r5a Gys1 Gys2 Phka1 Phka2 Gyg1 Ppp2r3a Pygb Phkg1 Ppp2r2c Phkg2 Ppp2r2b Agl Calm3 Calm2 Ppp2cb Ptpa Gsk3b Gsk3a Ppp2r2a Ppp2ca Ppp2r1a SULINDAC METABOLIC PATHWAY%WIKIPATHWAYS_20260710%WP2541%RATTUS NORVEGICUS Sulindac metabolic pathway Cyp1a1 Msra Msrb2 THICK ASCENDING LIMB TRANSPORTERS%WIKIPATHWAYS_20260710%WP3882%RATTUS NORVEGICUS Thick ascending limb transporters Kcnk12 Ca2 Ca4 Kcnq1 Slc12a7 Kcnj16 Clcnkb Clcnka Atp1b1 Slc9a3 Slc4a7 Slc12a1 Atp1a1 Slc9a2 Aqp1 NON HOMOLOGOUS END JOINING%WIKIPATHWAYS_20260710%WP1277%RATTUS NORVEGICUS Non homologous end joining Xrcc6 Rad50 Prkdc Xrcc4 IL 6 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP135%RATTUS NORVEGICUS IL 6 signaling pathway Map2k6 Il6 Map2k2 Raf1 Rps6ka2 Eif4e Pxn Ppp2r5b Ppp2r5a Mapkapk2 Stat5a Stat5b Hnf1a Gab1 Gab2 Mapk8 Foxo1 Ptk2 Bmx Jak2 Fos Erbb2 Il6st Ppp2r3b Hsp90aa1 Foxo4 Cdk5r1 Sgk1 Shc1 Ppp2r5c Cebpb Rps6kb1 Il6r Plcg1 Inppl1 Ncoa1 Cdk9 Rb1 Ppp2r5e Rac1 Fgr Ptk2b Cdk5 Map2k4 Grb2 Fyn Pik3r1 Bad Sos1 Pik3r2 Tec Fes Stat3 Hdac1 Cd40 Map3k7 Casp9 Map3k4 Jun Nfkb1 Casp3 Ppp2r3a Ppp2r2c Map2k1 Ppp2r2b Crebbp Foxo3 Jak1 Ppp2cb Nlk Ptpa Gsk3b Hck Socs3 Hspb1 Tmem97 Prkcd Btk Daxx Ptpn11 Lyn Mapk14 Mapk1 Mapk3 Mapt Eif4ebp1 Hras Akt1 Ppp2r2a Ppp2ca Ppp2r1a FOCAL ADHESION%WIKIPATHWAYS_20260710%WP188%RATTUS NORVEGICUS Focal adhesion Src Map2k2 Mapk7 Rac2 Mylk2 Erbb2 Rap1b Hgf Ccnd1 Itgb1 Met Tnc Comp Rock2 Ppp1r12a Tnn Tnr Col5a1 Pgf Reln Lama3 Lama4 Tln1 Thbs2 Thbs4 Blk Vasp Shc3 Srms Txk Chad Itga8 Itga6 Itga9 Pdgfa Itga3 Pdgfb Itga10 Cav3 Jun Cav2 Col1a1 Cav1 Tesk2 Tnk2 Col4a1 Col4a2 Ptk6 Col4a6 Igf1 Ibsp Pelo Itgax Itgav Itgae Itgal Diaph1 Itgad Itgb8 Itgb6 Itga2b Itgb5 Actn1 Itgb3 Col11a1 Col11a2 Lamb3 Vegfb Col6a2 Styk1 Zyx Pip5k1c Mapk12 Mapk1 Akt3 Akt2 Mapk4 Akt1 Ccnd2 Rap1a Egfr Actb Map2k6 Vegfd Vegfc Raf1 Vcl Pxn Kdr Pdgfrb Pdgfra Pik3cg Actg1 Igf1r Pik3cd Pik3ca Spp1 Mapk9 Map2k3 Mapk8 Ptk2 Pdpk1 Elk1 Pten Mylk Braf Shc1 Selenop Rac1 Fgr Grb2 Pik3r5 Ilk Fyn Pik3r1 Crk Bad Sos1 Pik3r2 Col1a2 Dock1 Bcar1 Pak1 Pak6 Pak3 Lama5 Pak2 Vtn Pak5 Pak4 Vwf Cdc42 Lamc1 Lamb1 Thbs1 Egf Map2k1 Itgam Rock1 Gsk3b Hck Itgb2 Mapk14 Rapgef1 Hras Capn1 STATIN PATHWAY%WIKIPATHWAYS_20260710%WP145%RATTUS NORVEGICUS Statin pathway Lpl Apoc1 Abca1 Cyp7a1 Scarb1 Hmgcr Apoe Mttp Soat1 Lcat STRIATED MUSCLE CONTRACTION%WIKIPATHWAYS_20260710%WP316%RATTUS NORVEGICUS Striated muscle contraction Actn4 Myl9 Actc1 Tnnt3 Acta1 Acta2 Tnnt2 Tnnt1 Tpm4 Tpm3 Tpm2 Neb Tnni3 Actg1 Tnni2 Tnni1 Vim Tnnc2 Tnnc1 Tmod1 Myh3 Actn3 Myl2 Mybpc3 NOTCH SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP517%RATTUS NORVEGICUS Notch signaling pathway Aph1a Ncstn Dtx2 Hdac1 Dtx3 Dtx4 Dvl1 Dll3 Rbpjl Maml1 Dll4 Mfng Numb Hes5 Jag2 Hes1 Jag1 Kat2a Rfng Numbl Notch1 Notch2 Lfng Notch3 Psen1 Psen2 Ctbp1 Crebbp Ctbp2 Dvl2 Dvl3 TNF ALPHA NF KB SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP457%RATTUS NORVEGICUS TNF alpha NF kB signaling pathway Src Psmd3 Tradd Gab1 Kcnq1 Prkcz Rps6kb1 Ywhah Ywhag Ywhae Ywhab Map3k8 Cav1 Map3k2 Casp3 Flna Hspb1 Tab2 Traf6 Nfkb2 Traf2 Akt2 Akt1 Ppp2ca Rack1 Ripk2 Nkiras1 Nr2c2 Nkiras2 Tbkbp1 Rps11 Rpl6 Ikbkb Rps13 Chuk Pias3 Ptk2 Fbl Ikbkg Ube2i Map3k14 Dpf2 Polr1b Rnf216 Rpl30 Polr1a Polr1g Prkaca Fbxw11 Polr1e Casp8ap2 Rela Txlna Tank Gtf2i Map3k3 Map3k1 Actl6a Smarce1 Tifa Ube2d2 Polr2sl1 Btrc Nfkbiz Glg1 Bag4 Ripk3 G3bp2 Dcaf7 Cops3 Capn3 Kpna6 Mcc Kpna3 Kpna2 Dap Cul1 Hdac2 Rel Ccar2 Traf4 Hdac1 Mcm7 Pfdn2 Faf1 Csnk2a1 Casp7 Tnfrsf8 Mark2 Smarcb1 Tnfrsf1b Alpl Rasal2 Akap8 Casp2 Ripk1 Csnk2b Tnfrsf1a Rpl8l1 Nfkb1 Cyld Fkbp5 Fadd Mcm5 Tnip2 Tnip1 Pdcd2 Nsmaf Zfand5 Commd1 Crebbp Trpc4ap Fancd2 Ktn1 Pebp1 Pkn1 Lrpprc Mtif2 Gsk3b Tnf Ptpn11 Psmc2 Nfkbia Psmc3 Nfkbib Psmd12 Elp1 Psmd13 Psmb5 Psmd6 WNT SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP375%RATTUS NORVEGICUS Wnt signaling pathway Raf1 Dvl1 Sox9 Arrb2 Arrb1 Pax2 Prkca Smad4 Mapk8ip1 Mapk9 Mapk8 Ccnd1 Rhoa Btrc Rac1 Cdk1 Cul1 Map3k7 Tbp Csnk2a1 Mark2 Csnk2b Jun Camk2g Prkcg Camk2d Ctnnb1 Apc Ctbp1 Wnt5a Camk2a Ctbp2 Nlk Cdh1 Gsk3b Axin1 Tax1bp3 Axin2 Skp1 Sfrp2 Prkcb Lef1 Sfrp1 Tmem97 Dkk1 Magi3 Lrp6 Ror2 Crybb2 Lrp5 Csnk1d Sall1 Wnt3a Cdc25c Dvl2 Senp2 Dvl3 Ruvbl1 Wnt7a Vangl2 Wnt2 Csnk1a1 Mapk1 Dab2 Wnt4 Tfap2a Brd7 Wnt3 Jup Mapk3 Map1b Ctnnbip1 Akt1 Ankrd6 Camk2b Fzd2 Bcl9 Fzd4 Dlg1 Fzd9 Dlg2 Fzd8 Dlg4 Tcf4 Nr5a1 Ppp2ca Hipk2 IRINOTECAN PATHWAY%WIKIPATHWAYS_20260710%WP124%RATTUS NORVEGICUS Irinotecan pathway Ces1f Ces1e Ces1d Ces2c Abcc1 Abcg2 Abcc2 Bche OSTEOBLAST SIGNALING%WIKIPATHWAYS_20260710%WP227%RATTUS NORVEGICUS Osteoblast signaling Col1a1 Pdgfrb Pdgfra Bglap Pth Tnfsf11 Fgf23 Slc34a1 SMALL LIGAND GPCRS%WIKIPATHWAYS_20260710%WP161%RATTUS NORVEGICUS Small ligand GPCRs Ptger2 Ptger3 Ptger1 Cnr2 Lpar1 Mtnr1a Ptgir Ptgfr Ptafr S1pr3 S1pr1 Cnr1 Ptgdr Ptger4 INSULIN INDUCED PI3K AKT AND MAPK IN HEPATOCYTES%WIKIPATHWAYS_20260710%WP4229%RATTUS NORVEGICUS Insulin induced PI3K Akt and MAPK in hepatocytes Bad Sos1 Raf1 Rptor Eif4e Mtor Pfkfb2 Rheb Foxk1 Akt1s1 Rps6 Tsc2 Tsc1 Gys1 Mlst8 Gys2 Acly Foxo1 Gsk3a Rps6ka1 Irs2 Grb10 Ins1 Shc1 Pik3c3 Rps6kb1 Mapk1 Mapk3 Eif4ebp1 Akt1 Grb2 ACETYLCHOLINE SYNTHESIS%WIKIPATHWAYS_20260710%WP360%RATTUS NORVEGICUS Acetylcholine synthesis Ache Pcyt1a Pdha1 Ahsg Chat Pemt GPCRS CLASS B SECRETIN LIKE%WIKIPATHWAYS_20260710%WP378%RATTUS NORVEGICUS GPCRs class B secretin like Glp2r Vipr1 Calcrl Adgrl2 Glp1r Adgrl3 Crhr2 Crhr1 Ghrhr Calcr Adgre5 Gipr Gcgr Adgre1 Sctr Adgrl4 Adcyap1r1 Adgrl1 MATRIX METALLOPROTEINASES%WIKIPATHWAYS_20260710%WP278%RATTUS NORVEGICUS Matrix metalloproteinases Mmp11 Cep295nl Mmp23 Mmp24 Mmp14 Tnf Mmp15 Mmp16 Mmp28 Timp3 Timp2 Timp4 Bsg Tcf20 Mmp21 Mmp2 Mmp9 IL 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP569%RATTUS NORVEGICUS IL 2 signaling pathway Rack1 Nr3c1 Raf1 Eif4e Mtor Ets2 Mapkapk2 Stat5a Stat5b Tert Pik3cg Pik3cd Pik3ca Mapk9 Gab2 Il2 Mknk1 Mapk8 Chuk Jak2 Ybx1 Rela Prkcz Shc1 Rps6kb1 Stam2 Cd53 Itm2b Ptk2b Stam Nmi Grb2 Fyn Pik3r1 Crk Sos1 Pik3r2 Stat3 Cxhxorf65 Il2ra Il2rg Lck Nfkb1 Syk Crkl Map2k1 Foxo3 Jak1 Socs3 Irs2 Ptpn6 Ptpn11 Lyn Mapk14 Mapk1 Plcb1 Mapk3 Akt1 Jak3 Eif3b GENETIC ALTERATIONS OF LUNG CANCER%WIKIPATHWAYS_20260710%WP1968%RATTUS NORVEGICUS Genetic alterations of lung cancer Tgfb2 Tgfb1 E2f1 Ccne1 Raf1 Cdkn1a Erbb2 Ccnd1 Tp53 Mapk1 Smad4 Rb1 Akt1 Dmp1 Map2k1 Pik3cd Pik3ca Mycb Mdm2 Crebbp Rasl11b Smad2 Necab3 Egfr BIOSYNTHESIS OF ALDOSTERONE AND CORTISOL%WIKIPATHWAYS_20260710%WP508%RATTUS NORVEGICUS Biosynthesis of aldosterone and cortisol Cyp17a1 Hsd3b6 Cyp21a1 WNT MYOFIBROBLASTIC ACTIVATION OF HEPATIC STELLATE CELLS%WIKIPATHWAYS_20260710%WP3649%RATTUS NORVEGICUS Wnt myofibroblastic activation of hepatic stellate cells Pparg Wnt3a HYPERTROPHY MODEL%WIKIPATHWAYS_20260710%WP442%RATTUS NORVEGICUS Hypertrophy model Ifrd1 Ccn1 Atf3 Nr4a3 Ifng Myog Eif4e Il1a Eif4ebp1 Ankrd1 Il1r1 Jund Wdr1 Hbegf Zeb1 Dusp14l1 PHASE I BIOTRANSFORMATIONS NON P450%WIKIPATHWAYS_20260710%WP1291%RATTUS NORVEGICUS Phase I biotransformations non P450 Pon3 Ces5a Pon1 Pon2 Ces2j Esd Lipa VEGF RECEPTOR SIGNAL TRANSDUCTION%WIKIPATHWAYS_20260710%WP1965%RATTUS NORVEGICUS VEGF receptor signal transduction Bad Nos3 Src Vegfc Pik3r3 Raf1 Vegfb Sh2d2a Casp9 Hspbp1 Pxn Shc1 Mapkapk2 Mapk1 Plcg1 Prkca Rac1 Akt1 Grb2 Pgf Prkci CARDIOVASCULAR SIGNALING%WIKIPATHWAYS_20260710%WP590%RATTUS NORVEGICUS Cardiovascular signaling Thbs2 Map2k6 Vegfd Arhgef7 Casp6 Capn6 Hspa1b Casp2 Vwf Col1a1 Pdgfra Casp3 Rras2 Col4a1 Col4a2 Wasf1 Egf Stmn1 Mapk8 Hspb1 Col11a1 Erbb2 Wnt2 Selenop Vav2 Tnc Akt1 Col5a1 Pgf Cfl1 FRUCTOSE METABOLISM IN PROXIMAL TUBULES%WIKIPATHWAYS_20260710%WP3894%RATTUS NORVEGICUS Fructose metabolism in proximal tubules Psme3 G6pc1 Slc5a10 Hk1 Sord Khk Naglt1 Akr1b1 Tpi1 Slc2a5 Tkfc Fbp1 Aldob Aldoa Pfkl Pfkp Slc5a9 Gpi INTEGRIN MEDIATED CELL ADHESION%WIKIPATHWAYS_20260710%WP74%RATTUS NORVEGICUS Integrin mediated cell adhesion Map2k6 Src Map2k2 Raf1 Vcl Arhgef7 Pxn Mapk7 Itga1 Rac2 Mylk2 Map2k3 Pdpk1 Ptk2 Braf Rap1b Selenop Itgb1 Shc1 Vav2 Rac1 Rock2 Grb2 Capn3 Mapk10 Ilk Fyn Tln1 Crk Sos1 Pik3r2 Vasp Shc3 Dock1 Bcar1 Itga8 Pak1 Itga6 Pak6 Itga9 Capn6 Itga3 Pak3 Vav3 Pak2 Itgb4 Itga10 Itga2 Pak4 Cav3 Cdc42 Capn9 Cav2 Git2 Cav1 Capn5 Capn7 Capn2 Map2k1 Itgax Itgam Itgav Itgae Rock1 Itgal Itgad Itgb8 Itgb6 Itga2b Itgb5 Itgb3 Itgb2 Zyx Mapk12 Mapk1 Rapgef1 Akt3 Akt2 Hras Mapk4 Akt1 Rap1a Capn1 Capns1 Rho NUCLEAR FACTOR ERYTHROID DERIVED 2 LIKE 2 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP2376%RATTUS NORVEGICUS Nuclear factor erythroid derived 2 like 2 signaling pathway Dhcr7 Mapk7 Prkca Slc2a1 Prkcz Ftl1 Fth1 Ugdh Abcc1 Cdkn1a Map3k7 Taldo1 Txn Tp53 Acta1 Jun Prkcg Prkd3 Ube2k Herpud1 Prdx1 Abcc4 Pmf1 Mafg Ubb Slc1a4 Mafk Prkci Actg2 Bach1 Slc35b1 Dnajc5 Actc1 Aldh3a1 Sod1 Xpo1 Gsto2 Mgst2 Cbr1 Pik3r6 Dnajb4 Nqo1 Gstm1 Nqo2 Usp14 Ran Acta2 Mapk1 Vcp Mapk3 Fosl1 Prkce Actb Nras Map2k6 Raf1 Akr7a3 Akr7a2 Ephx1 Rras2 Actg1 Pik3cd Pik3ca Pik3c2b Mapk9 Pik3c2a Mapk8 Pik3c2g Abcc3 Prkcq Map3k1 Pik3c3 Map2k7 Ldhb Aldoa Sod3 Sod2 Rras Pik3r5 Fyn Pik3r1 Gstk1 Pik3r2 Gsto1 Pik3r3 Mgst1 Gstp1 Hmox1 Nfe2l2 Map2k1 Crebbp Brca1 Gstm5 Gsk3b Gstm4 Prkcb Scarb1 Prkcd Psmc6 Psmc5 Gss Fmo1 Psmc2 Gstm6 Mapk14 Gstm3 Gstm2 Psmc4 Sqstm1 Psmc3 G6pdx Gstt2 Gstt1 Gclm Akr1b10 Hras Eif2ak3 Akr1a1 MIR219 IN OLIGODENDROCYTE DIFFERENTIATION AND MYELINATION%WIKIPATHWAYS_20260710%WP2811%RATTUS NORVEGICUS mir219 in oligodendrocyte differentiation and myelination Neurod1 Sox6 Pdgfra Hes5 Zbtb18 Foxj3 Elovl7 INSULIN SIGNALING%WIKIPATHWAYS_20260710%WP439%RATTUS NORVEGICUS Insulin signaling Map2k2 Rptor Eif4e Mtor Rheb Tsc2 Tsc1 Gys1 Gys2 Prkca Gyg1 Rac2 Lipe Slc2a1 Gab1 Prkch Slc2a4 Rps6kb2 Foxo1 Prkcz Egr1 Sgk1 Rps6kb1 Inppl1 Shc3 Map3k8 Map3k7 Map3k6 Map3k5 Map3k4 Jun Map3k2 Prkci Map4k3 Map4k2 Map4k1 Mapk12 Mapk1 Cyth3 Grb14 Stxbp1 Mapk3 Stxbp2 Akt2 Stxbp3 Mapk4 Stxbp4 Akt1 Prkaa1 Kif5b Cblc Rps6ka3 Insr Rps6ka4 Map3k9 Flot2 Flot1 Rps6ka5 Map4k5 Rab4a Xbp1 Kif3a Prkaa2 Tbc1d4 Map2k6 Ehd1 Snap23 Ehd2 Raf1 Snap25 Arf1 Rhoj Rps6ka2 Ptprf Cap1 Rrad Inpp4a Ppp1r3a Vamp2 Rps6ka6 Mink1 Sgk3 Sgk2 Myo1c Enpp1 Ptpn1 Pik3cg Stx4 Arhgap33 Igf1r Map3k10 Pik3cd Mapk11 Mapk9 Pik3c2a Ikbkb Mapk8 Pik3c2g Pdpk1 Map3k11 Elk1 Pten Map3k14 Prkcq Fos Reg1 Grb10 Map3k3 Map3k1 Shc1 Pik3c3 Map2k7 Cblb Mapk13 Rac1 Map2k4 Grb2 Pfkl Mapk10 Sos2 Pik3r1 Crk Sos1 Pik3r2 Map2k1 Foxo3 Gsk3b Gsk3a Prkcb Rps6ka1 Trib3 Prkcd Irs2 Shc2 Ptpn11 Mapk14 Sh2b2 Rapgef1 Eif4ebp1 Hras GLUCOCORTICOID EFFECT ON TARGET GENE EXPRESSION%WIKIPATHWAYS_20260710%WP1963%RATTUS NORVEGICUS Glucocorticoid effect on target gene expression Nr3c1 Anxa1 Nfkb1 Nfkbia Pla2g4a Tsc22d3 Hspa4 Mt-co2 Rras Fkbp4 ONE CARBON METABOLISM%WIKIPATHWAYS_20260710%WP1292%RATTUS NORVEGICUS One carbon metabolism Mtr Ftcd Ahcyl2 Bhmt Tcn2 Dnmt3a Aldh1l1 Shmt1 Mat1a Gart Dhfr Mthfr Mthfd2 Mthfd1l Ahcy Folh1 Mtrr APOPTOSIS%WIKIPATHWAYS_20260710%WP1290%RATTUS NORVEGICUS Apoptosis Irf3 Tradd Irf7 Irf5 Birc5 Bcl2l11 Igf1r Ikbkb Chuk Ikbkg Prf1 Hells Rela Traf1 Pmaip1 Bcl2l2 Xiap Map3k1 Bnip3l Lta Irf4 Irf6 Diablol1 Irf1 Bak1 Irf2 Tp73 Tnfrsf25 Igf2 Tp63 Map2k4 Tnfrsf10b Mapk10 Pik3r1 Bad Fas Casp7 Casp9 Tnfrsf1b Tp53 Casp2 Ripk1 Tnfrsf1a Jun Nfkb1 Fadd Casp3 Faslg Dffa Bid Dffb Nfkbia Traf2 Bax Nfkbib Akt1 NUCLEAR RECEPTORS%WIKIPATHWAYS_20260710%WP217%RATTUS NORVEGICUS Nuclear receptors Nr3c1 Esr2 Ror1 Nr5a2 Nr4a2 Nr1i3 Nr1i2 Nr2c2 Esr1 Rara Rarb Vdr Nr2f1 Ppard Rxrb Ppara Pparg Nr1h3 Rxra Nr2e1 Hnf4a Esrra Esrrb Nr2f6 Thrb Nr1d2 Thra Nr2f2 Rxrg Nr5a1 Rorc Nr1h2 P53 PATHWAY%WIKIPATHWAYS_20260710%WP655%RATTUS NORVEGICUS p53 pathway Sesn1 Chek2 Fas Zmat3 Cdkn1a Serpinb5 Cdkn2a Shisa5 Casp9 Sfnl1 Cycs Adgrb1 Ccnb1 Cd82 Tp53 Cdk6 Tsc2 Mdm4 Ppm1d Rchy1 Casp3 Bid Igfbp3 Ccng1 Chek1 Pten Ccne1 Siah1 Perp Pmaip1 Gadd45a Rprm Tp73 Bax Cdk1 Serpine1 G PROTEIN SIGNALING PATHWAYS%WIKIPATHWAYS_20260710%WP73%RATTUS NORVEGICUS G protein signaling pathways Nras Arhgef1 Prkca Slc9a1 Prkaca Prkcq Gnaq Prkcz Ppp3ca Gngt1 Gnb2 Gnb1 Rhoa Gnb3 Gng13 Rras Itpr1 Adcy3 Adcy4 Adcy2 Gna12 Adcy7 Gna13 Adcy5 Adcy9 Pde4b Akap8 Prkar1a Prkar1b Pde7b Pde7a Prkcg Akap7 Prkd3 Akap3 Akap4 Gng3 Akap1 Gnaz Akap10 Akap11 Akap12 Akap9 Akap13 Pde8a Pde8b Prkci Kcnj3 Pde4d Pakap Gng8 Gna14 Gnao1 Prkar2b Prkcb Gnal Gng5 Pde4c Ppp3cc Prkcd Gnas Pde1c Pde1a Gng11 Plcb3 Hras Prkacb Gnai1 Gnai3 Prkce Adcy8 ETHANOL METABOLISM RESULTING IN PRODUCTION OF ROS BY CYP2E1%WIKIPATHWAYS_20260710%WP4268%RATTUS NORVEGICUS Ethanol metabolism resulting in production of ROS by CYP2E1 Prkcb Cyp2e1 Map2k1 Nfe2l2 Mafg Mapk8 HEDGEHOG SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP574%RATTUS NORVEGICUS Hedgehog signaling pathway Smo Hhip Ccnb1 Gli1 Gli3 Gli2 Ski Shh Ptch2 Ptch1 Sufu Igf2 Sap18 Dyrk1a Cdk1 Crebbp ERBB SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP1299%RATTUS NORVEGICUS ErbB signaling pathway Bad Crk Sos1 Src Tgfa Cdkn1a Mtor Pak4 Jun Stat5a Prkca Egf Map2k1 Gab1 Camk2a Mapk8 Ptk2 Elk1 Gsk3b Erbb2 Shc2 Map2k7 Rps6kb1 Mapk1 Plcg1 Akt3 Cdkn1b Eif4ebp1 Ereg Hras Nrg2 Nrg1 Grb2 Areg Cblc Btc Nrg4 Nrg3 Pik3r5 Hbegf Abl1 Egfr GLUCURONIDATION%WIKIPATHWAYS_20260710%WP1276%RATTUS NORVEGICUS Glucuronidation Ugt2b34 Pgm1 Ugt2a1 Ugt2b1 Hk1 Ugt2b7 Ugp2 Pgm2 Pgm5 Ugt2b35 Ugdh CATECHOLAMINE SYNTHESIS%WIKIPATHWAYS_20260710%WP513%RATTUS NORVEGICUS Catecholamine synthesis Ddc Th Pah Dbh Pnmt G1 TO S CELL CYCLE CONTROL%WIKIPATHWAYS_20260710%WP348%RATTUS NORVEGICUS G1 to S cell cycle control Ccna1 Ccne2 Cdkn2b Tfdp1 Cdkn2c Cldn5 Myt1 Mcm4 Mcm6 Mcm2 Pole2 Pola2 Ccng2 Creb3l4 Creb3l1 Orc5 Rpa3l1 Orc4 Orc6 Orc1 Orc3 Mdm2 Rpa2 Necab3 Wee1 E2f3 E2f4 E2f6 Pole Cdkn1c Ccne1 Rbl1 Atf6b Gadd45a Ccnd1 Rb1 Cdk1 E2f5 Mnat1 E2f1 Mcm7 Cdkn1a Ccnh Creb3 Ccnb1 Tp53 Cdk6 Mcm5 Cdk7 Pcna Cdkn1b G13 SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP520%RATTUS NORVEGICUS G13 signaling pathway Pik3r2 Pip4k2a Arhgef1 Pak3 Map3k4 Cdc42 Tnk2 Pik3cd Limk1 Rock1 Diaph1 Pkn1 Arhgdib Iqgap2 Ppp1cb Wasl Sh3rf1 Cit Cyfip1 Mybph Rps6kb1 Rac1 Rock2 Mapk10 Cfl2 PEPTIDE GPCRS%WIKIPATHWAYS_20260710%WP131%RATTUS NORVEGICUS Peptide GPCRs Npy2r Ghsr Npy1r Mc3r Cxcr1 Oprd1 Tacr1 Ednra Gnrhr Oprk1 Ntsr1 Cxcr4 Fshr Oprl1 Ccr5 Ccr2 Galr2 Cckbr Galr3 Galr1 Agtr1 Lhcgr Sstr5 Sstr2 Sstr4 Sstr3 Cxcr6 Sstr1 Tacr3 Avpr1b Tacr2 Mc5r Tshr Oprm1 Tac4 Fpr1 Nmbr Fpr3 Bdkrb1 Fpr2 Ccr10 Grpr Oxtr C3ar1 Cckar Ednrb Npy5r Ntsr2 Brs3 Mc2r Agtr2 Bdkrb2 Ccr7 Ccr6 Ccr3 Npy4r Mc4r OSTEOCLAST%WIKIPATHWAYS_20260710%WP489%RATTUS NORVEGICUS Osteoclast Ctsk Atp6v1e1 Itgb3 Ifnb1 Slc9a1 Tnfsf11 Ifnar1 Spp1 Trpv5 Zcchc2 SELENIUM MICRONUTRIENT NETWORK %WIKIPATHWAYS_20260710%WP1310%RATTUS NORVEGICUS Selenium micronutrient network Mtr Kmo Sod1 Ptgds Cat Tbxas1 Pnpo Xdh Mt-co2 Mthfr Selenok Gpx3 Selenop Fads1 Fads2 Ptgis Mt-co1 Gpx1 Gpx6 Alox5 ATM SIGNALING PATHWAY%WIKIPATHWAYS_20260710%WP654%RATTUS NORVEGICUS ATM signaling pathway E2f1 Ccne1 Chek2 Cdkn1a Casp9 Sfnl1 Cycs Pmaip1 Ccnb1 Gadd45a Rprm Ccnd1 Cdk6 Tp53 Bak1 Casp3 Rb1 Bax Cdk1 Necab3 Brca1