Dataset | Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos |
Phenotype | phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos |
Upregulated in class | transDMproB |
GeneSet | PROTEIN_KINASE_CASCADE |
Enrichment Score (ES) | 0.60989034 |
Normalized Enrichment Score (NES) | 1.5043811 |
Nominal p-value | 0.0015174507 |
FDR q-value | 0.2811477 |
FWER p-Value | 0.989 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | DUSP6 | 19891 3399 | 15 | 4.550 | 0.0521 | Yes | ||
2 | SCOTIN | 3136 19299 3102 | 55 | 3.284 | 0.0881 | Yes | ||
3 | STAT4 | 14251 9907 | 76 | 2.969 | 0.1216 | Yes | ||
4 | MAPK9 | 1233 20903 1383 | 85 | 2.800 | 0.1537 | Yes | ||
5 | TSPAN6 | 2616 24068 | 138 | 2.384 | 0.1786 | Yes | ||
6 | MAPKAPK2 | 13838 | 146 | 2.333 | 0.2053 | Yes | ||
7 | LGALS9 | 1441 20332 1200 | 177 | 2.226 | 0.2296 | Yes | ||
8 | IL12A | 4913 | 186 | 2.203 | 0.2548 | Yes | ||
9 | TNFAIP3 | 19810 | 262 | 1.874 | 0.2725 | Yes | ||
10 | SOCS2 | 5694 | 265 | 1.860 | 0.2940 | Yes | ||
11 | MAP4K2 | 6457 | 348 | 1.618 | 0.3083 | Yes | ||
12 | CD81 | 8719 | 401 | 1.542 | 0.3234 | Yes | ||
13 | STAT1 | 3936 5524 | 443 | 1.477 | 0.3384 | Yes | ||
14 | SQSTM1 | 9517 | 505 | 1.326 | 0.3505 | Yes | ||
15 | LGALS1 | 22429 | 520 | 1.286 | 0.3647 | Yes | ||
16 | STAT3 | 5525 9906 | 534 | 1.263 | 0.3786 | Yes | ||
17 | EDG5 | 19216 | 543 | 1.255 | 0.3928 | Yes | ||
18 | MAP3K3 | 20626 | 561 | 1.226 | 0.4061 | Yes | ||
19 | LITAF | 7149 | 575 | 1.214 | 0.4195 | Yes | ||
20 | DUSP2 | 14865 | 619 | 1.119 | 0.4302 | Yes | ||
21 | STK17B | 13957 | 752 | 0.964 | 0.4342 | Yes | ||
22 | CASP1 | 19577 | 784 | 0.934 | 0.4434 | Yes | ||
23 | CXCR4 | 13844 | 809 | 0.913 | 0.4527 | Yes | ||
24 | PTEN | 5305 | 930 | 0.798 | 0.4555 | Yes | ||
25 | MAP3K5 | 20079 11166 | 996 | 0.734 | 0.4605 | Yes | ||
26 | MAP3K11 | 11163 | 1013 | 0.714 | 0.4679 | Yes | ||
27 | CD27 | 16994 | 1050 | 0.684 | 0.4739 | Yes | ||
28 | TRAF6 | 5797 14940 | 1054 | 0.682 | 0.4817 | Yes | ||
29 | RIPK1 | 5381 | 1092 | 0.657 | 0.4873 | Yes | ||
30 | SOD1 | 9846 | 1109 | 0.648 | 0.4940 | Yes | ||
31 | MAP4K3 | 22887 | 1118 | 0.641 | 0.5010 | Yes | ||
32 | ICK | 7135 12146 | 1150 | 0.618 | 0.5065 | Yes | ||
33 | STAT5A | 20664 | 1181 | 0.601 | 0.5118 | Yes | ||
34 | MAPK14 | 23313 | 1184 | 0.600 | 0.5187 | Yes | ||
35 | MAP3K7IP2 | 19827 | 1186 | 0.599 | 0.5256 | Yes | ||
36 | TNFSF10 | 15626 | 1198 | 0.592 | 0.5319 | Yes | ||
37 | HCLS1 | 22770 | 1209 | 0.589 | 0.5382 | Yes | ||
38 | NDFIP2 | 21941 | 1230 | 0.579 | 0.5439 | Yes | ||
39 | CRKL | 4560 | 1245 | 0.572 | 0.5497 | Yes | ||
40 | SOCS3 | 20131 | 1254 | 0.567 | 0.5559 | Yes | ||
41 | TICAM2 | 23440 | 1260 | 0.564 | 0.5622 | Yes | ||
42 | CASP8 | 8694 | 1276 | 0.558 | 0.5679 | Yes | ||
43 | PIAS1 | 7126 | 1335 | 0.531 | 0.5709 | Yes | ||
44 | STAMBP | 17097 | 1394 | 0.506 | 0.5736 | Yes | ||
45 | MARK2 | 8899 | 1442 | 0.486 | 0.5767 | Yes | ||
46 | BST2 | 18845 | 1449 | 0.483 | 0.5820 | Yes | ||
47 | FKBP1A | 2801 | 1527 | 0.449 | 0.5830 | Yes | ||
48 | NOD1 | 17141 | 1537 | 0.445 | 0.5877 | Yes | ||
49 | PKN1 | 11567 6799 | 1655 | 0.395 | 0.5859 | Yes | ||
50 | MAP4K4 | 11241 | 1693 | 0.381 | 0.5883 | Yes | ||
51 | TBK1 | 12137 | 1706 | 0.376 | 0.5920 | Yes | ||
52 | MKNK2 | 3299 9392 | 1789 | 0.349 | 0.5916 | Yes | ||
53 | RPS6KA4 | 23804 | 1799 | 0.345 | 0.5952 | Yes | ||
54 | TEC | 16514 | 1837 | 0.330 | 0.5970 | Yes | ||
55 | STK3 | 7084 | 1848 | 0.328 | 0.6002 | Yes | ||
56 | EEF1D | 12393 2309 | 1877 | 0.319 | 0.6024 | Yes | ||
57 | PRDX4 | 24026 | 1895 | 0.314 | 0.6052 | Yes | ||
58 | STK4 | 14743 | 1926 | 0.308 | 0.6071 | Yes | ||
59 | GJA1 | 20023 | 1992 | 0.287 | 0.6069 | Yes | ||
60 | CCM2 | 20950 | 1999 | 0.285 | 0.6099 | Yes | ||
61 | STAT2 | 19840 | 2087 | 0.261 | 0.6082 | No | ||
62 | BIRC2 | 4397 4398 | 2182 | 0.236 | 0.6058 | No | ||
63 | IKBKE | 67 | 2217 | 0.225 | 0.6066 | No | ||
64 | BCL10 | 15397 | 2237 | 0.220 | 0.6081 | No | ||
65 | MAP3K4 | 23126 | 2282 | 0.210 | 0.6081 | No | ||
66 | SH2D3C | 2864 | 2332 | 0.196 | 0.6078 | No | ||
67 | OTUD7B | 10483 | 2421 | 0.178 | 0.6050 | No | ||
68 | RELA | 23783 | 2432 | 0.175 | 0.6065 | No | ||
69 | CAMKK2 | 9870 | 2492 | 0.162 | 0.6052 | No | ||
70 | EDG2 | 9033 | 2513 | 0.159 | 0.6060 | No | ||
71 | F2R | 21386 | 2542 | 0.155 | 0.6062 | No | ||
72 | EGF | 15169 | 2619 | 0.142 | 0.6038 | No | ||
73 | HIPK2 | 17180 | 2643 | 0.138 | 0.6041 | No | ||
74 | F2 | 14524 | 2685 | 0.132 | 0.6034 | No | ||
75 | MAST1 | 12143 | 2691 | 0.131 | 0.6047 | No | ||
76 | PAK1 | 9527 | 2868 | 0.104 | 0.5963 | No | ||
77 | IFNAR2 | 22705 1699 | 3176 | 0.074 | 0.5804 | No | ||
78 | MAPK13 | 23314 | 3196 | 0.072 | 0.5802 | No | ||
79 | SLC20A1 | 14855 | 3227 | 0.069 | 0.5794 | No | ||
80 | FYN | 3375 3395 20052 | 3271 | 0.066 | 0.5778 | No | ||
81 | MAP4K5 | 11853 21048 2101 2142 | 3298 | 0.063 | 0.5771 | No | ||
82 | NF1 | 5165 | 3443 | 0.054 | 0.5699 | No | ||
83 | PPM1A | 5279 9607 | 3495 | 0.050 | 0.5677 | No | ||
84 | TLR6 | 215 16528 | 3532 | 0.048 | 0.5663 | No | ||
85 | PINK1 | 12752 15703 | 3577 | 0.045 | 0.5645 | No | ||
86 | HGS | 20568 | 3586 | 0.045 | 0.5645 | No | ||
87 | ECM1 | 15246 1892 | 3642 | 0.043 | 0.5620 | No | ||
88 | GHRL | 1183 17040 | 3710 | 0.039 | 0.5589 | No | ||
89 | RGS3 | 2434 2474 6937 11935 2374 2332 2445 2390 | 3763 | 0.037 | 0.5565 | No | ||
90 | SNF1LK2 | 6168 10649 | 3868 | 0.034 | 0.5512 | No | ||
91 | WNK4 | 7644 | 3893 | 0.033 | 0.5503 | No | ||
92 | DUSP4 | 18632 3820 | 3938 | 0.031 | 0.5482 | No | ||
93 | LTBR | 16993 | 3995 | 0.029 | 0.5455 | No | ||
94 | TPD52L1 | 3420 19793 | 4048 | 0.027 | 0.5430 | No | ||
95 | MAP3K7IP1 | 2193 2171 22419 | 4071 | 0.027 | 0.5421 | No | ||
96 | TRIP6 | 16331 | 4116 | 0.025 | 0.5400 | No | ||
97 | MADD | 2926 14526 | 4121 | 0.025 | 0.5401 | No | ||
98 | FPR1 | 23115 | 4195 | 0.023 | 0.5364 | No | ||
99 | WNK3 | 24227 | 4252 | 0.022 | 0.5336 | No | ||
100 | TRAF2 | 14657 | 4330 | 0.020 | 0.5296 | No | ||
101 | PROK2 | 17057 | 4466 | 0.018 | 0.5225 | No | ||
102 | SRPK2 | 5513 | 4494 | 0.017 | 0.5212 | No | ||
103 | FYB | 10717 | 4600 | 0.016 | 0.5157 | No | ||
104 | C5AR1 | 17957 | 4635 | 0.015 | 0.5140 | No | ||
105 | IFNAR1 | 22703 | 4780 | 0.014 | 0.5063 | No | ||
106 | WNK1 | 1109 17020 6106 | 4831 | 0.013 | 0.5038 | No | ||
107 | SHC1 | 9813 9812 5430 | 4950 | 0.012 | 0.4975 | No | ||
108 | LATS2 | 11923 6928 | 5007 | 0.012 | 0.4946 | No | ||
109 | MAP3K6 | 16054 | 5180 | 0.011 | 0.4853 | No | ||
110 | MAP3K10 | 3831 17916 | 5288 | 0.010 | 0.4796 | No | ||
111 | SPRED2 | 8539 4332 | 5325 | 0.010 | 0.4778 | No | ||
112 | TNFRSF10B | 21971 10205 5781 10204 | 5374 | 0.009 | 0.4753 | No | ||
113 | CD40 | 10207 2961 2968 5783 | 5395 | 0.009 | 0.4743 | No | ||
114 | IL20 | 13840 | 5401 | 0.009 | 0.4741 | No | ||
115 | ECT2 | 15367 | 5528 | 0.008 | 0.4674 | No | ||
116 | NEK6 | 15018 | 5530 | 0.008 | 0.4674 | No | ||
117 | DUSP10 | 4003 14016 | 5533 | 0.008 | 0.4674 | No | ||
118 | CHRNA7 | 17808 | 5647 | 0.008 | 0.4613 | No | ||
119 | IRAK1BP1 | 19367 | 5682 | 0.008 | 0.4596 | No | ||
120 | NDFIP1 | 23573 | 5766 | 0.007 | 0.4551 | No | ||
121 | MAP3K13 | 22814 | 5891 | 0.007 | 0.4485 | No | ||
122 | EPGN | 16798 | 5967 | 0.006 | 0.4445 | No | ||
123 | STAT5B | 20222 | 5994 | 0.006 | 0.4431 | No | ||
124 | DUSP16 | 1004 7699 | 6041 | 0.006 | 0.4407 | No | ||
125 | RHOC | 15467 | 6066 | 0.006 | 0.4395 | No | ||
126 | SOCS6 | 12042 7044 | 6067 | 0.006 | 0.4395 | No | ||
127 | ADORA2B | 20850 | 6092 | 0.006 | 0.4383 | No | ||
128 | ITGB1BP1 | 9189 | 6207 | 0.006 | 0.4321 | No | ||
129 | TDGF1 | 5704 10108 | 6231 | 0.005 | 0.4310 | No | ||
130 | STK38 | 23045 | 6366 | 0.005 | 0.4237 | No | ||
131 | ADRB3 | 18901 | 6525 | 0.004 | 0.4152 | No | ||
132 | TAOK2 | 10610 3794 | 6706 | 0.004 | 0.4054 | No | ||
133 | SCG2 | 5410 14425 | 6893 | 0.003 | 0.3953 | No | ||
134 | GNG3 | 23752 | 6945 | 0.003 | 0.3926 | No | ||
135 | NMI | 14590 | 6984 | 0.003 | 0.3906 | No | ||
136 | CCR2 | 19250 | 7058 | 0.003 | 0.3866 | No | ||
137 | DUSP8 | 9493 | 7186 | 0.003 | 0.3797 | No | ||
138 | TRIM13 | 7313 | 7410 | 0.002 | 0.3676 | No | ||
139 | FASLG | 13789 | 7513 | 0.002 | 0.3621 | No | ||
140 | CCL2 | 9788 | 7589 | 0.002 | 0.3580 | No | ||
141 | LYN | 16281 | 7607 | 0.002 | 0.3571 | No | ||
142 | MBIP | 21063 2072 | 7726 | 0.001 | 0.3507 | No | ||
143 | DAPK1 | 7632 | 7754 | 0.001 | 0.3492 | No | ||
144 | DUSP22 | 466 21680 | 7802 | 0.001 | 0.3467 | No | ||
145 | DUSP9 | 24307 | 8206 | -0.000 | 0.3248 | No | ||
146 | HTR2B | 13900 | 8212 | -0.000 | 0.3245 | No | ||
147 | ADRA2A | 4355 | 8248 | -0.000 | 0.3226 | No | ||
148 | EDARADD | 5056 3282 3278 | 8327 | -0.000 | 0.3183 | No | ||
149 | ERC1 | 1013 17021 995 1136 | 8341 | -0.000 | 0.3176 | No | ||
150 | SGK2 | 14750 | 8493 | -0.001 | 0.3094 | No | ||
151 | NRTN | 22923 | 8539 | -0.001 | 0.3070 | No | ||
152 | TGFA | 17381 | 8815 | -0.001 | 0.2920 | No | ||
153 | MAP2K4 | 20405 | 9477 | -0.003 | 0.2561 | No | ||
154 | MAP2K7 | 6453 | 9567 | -0.003 | 0.2513 | No | ||
155 | RHOH | 13226 | 9634 | -0.003 | 0.2477 | No | ||
156 | STK38L | 17240 | 9639 | -0.003 | 0.2476 | No | ||
157 | RPL17 | 11429 6653 | 9960 | -0.004 | 0.2302 | No | ||
158 | EDA2R | 6364 | 10036 | -0.004 | 0.2261 | No | ||
159 | MARK1 | 5955 | 10038 | -0.004 | 0.2261 | No | ||
160 | CLCF1 | 12160 3742 | 10049 | -0.004 | 0.2256 | No | ||
161 | CXXC5 | 12523 | 10097 | -0.004 | 0.2231 | No | ||
162 | NOD2 | 6384 | 10118 | -0.005 | 0.2221 | No | ||
163 | SRC | 5507 | 10223 | -0.005 | 0.2165 | No | ||
164 | ADRA1B | 4354 | 10464 | -0.005 | 0.2035 | No | ||
165 | IL22RA2 | 20082 | 10734 | -0.006 | 0.1889 | No | ||
166 | MAPK8IP3 | 11402 23080 | 11006 | -0.007 | 0.1743 | No | ||
167 | RGS4 | 9724 | 11090 | -0.007 | 0.1698 | No | ||
168 | FGFR1 | 3789 8968 | 11379 | -0.008 | 0.1542 | No | ||
169 | MINK1 | 20802 | 11444 | -0.009 | 0.1509 | No | ||
170 | MAPK10 | 11169 | 11763 | -0.010 | 0.1337 | No | ||
171 | TNFSF14 | 1584 22914 | 11799 | -0.010 | 0.1319 | No | ||
172 | TNFSF15 | 15863 | 11807 | -0.010 | 0.1316 | No | ||
173 | RPS6KA2 | 9759 9758 | 11842 | -0.010 | 0.1299 | No | ||
174 | FAF1 | 2508 16137 8951 | 11881 | -0.011 | 0.1279 | No | ||
175 | PLCE1 | 13156 | 11989 | -0.011 | 0.1223 | No | ||
176 | MAP3K9 | 6872 | 12049 | -0.011 | 0.1192 | No | ||
177 | NEK11 | 3099 19016 | 12162 | -0.012 | 0.1132 | No | ||
178 | RPS6KA5 | 2076 21005 | 12243 | -0.012 | 0.1090 | No | ||
179 | NF2 | 1222 5166 | 12322 | -0.013 | 0.1049 | No | ||
180 | CFLAR | 8738 4517 | 12477 | -0.014 | 0.0967 | No | ||
181 | FGFR3 | 8969 3566 | 12834 | -0.016 | 0.0775 | No | ||
182 | RIPK2 | 2528 15935 | 12909 | -0.017 | 0.0737 | No | ||
183 | SECTM1 | 20104 | 13120 | -0.019 | 0.0624 | No | ||
184 | CARTPT | 21374 | 13134 | -0.019 | 0.0620 | No | ||
185 | IL31RA | 21347 | 13153 | -0.019 | 0.0612 | No | ||
186 | GADD45G | 21637 | 13491 | -0.022 | 0.0431 | No | ||
187 | DAXX | 23290 | 13619 | -0.024 | 0.0365 | No | ||
188 | MDFI | 22950 | 13625 | -0.024 | 0.0365 | No | ||
189 | FGF2 | 15608 | 13664 | -0.025 | 0.0347 | No | ||
190 | IKBKG | 2570 2562 4908 | 13789 | -0.027 | 0.0283 | No | ||
191 | RHOA | 8624 4409 4410 | 13910 | -0.029 | 0.0221 | No | ||
192 | PRKAG3 | 6295 | 13922 | -0.029 | 0.0218 | No | ||
193 | CANT1 | 13304 | 13933 | -0.029 | 0.0216 | No | ||
194 | GPS1 | 1392 9943 5550 9944 | 13946 | -0.030 | 0.0213 | No | ||
195 | CARD10 | 22214 8376 | 14059 | -0.031 | 0.0156 | No | ||
196 | ADRA1A | 2850 8560 | 14214 | -0.035 | 0.0076 | No | ||
197 | AKAP11 | 2695 | 14376 | -0.039 | -0.0007 | No | ||
198 | GRM4 | 332 | 14475 | -0.041 | -0.0056 | No | ||
199 | ATP6AP2 | 2567 24380 2579 2656 | 14477 | -0.041 | -0.0052 | No | ||
200 | MAPK8IP2 | 77 | 14498 | -0.042 | -0.0058 | No | ||
201 | MAPK11 | 2264 9618 22163 | 14587 | -0.045 | -0.0100 | No | ||
202 | SPRED1 | 4331 | 14767 | -0.050 | -0.0192 | No | ||
203 | TNFRSF1A | 1181 10206 | 14806 | -0.052 | -0.0207 | No | ||
204 | MAP3K2 | 11165 | 14854 | -0.054 | -0.0226 | No | ||
205 | REL | 9716 | 15085 | -0.066 | -0.0343 | No | ||
206 | ATP2C1 | 10660 6178 | 15126 | -0.068 | -0.0357 | No | ||
207 | MAP3K7 | 16255 | 15267 | -0.077 | -0.0424 | No | ||
208 | MYD88 | 18970 | 15312 | -0.080 | -0.0439 | No | ||
209 | BLK | 3205 21791 | 15497 | -0.094 | -0.0528 | No | ||
210 | IRAK2 | 17324 | 15597 | -0.104 | -0.0570 | No | ||
211 | MAP3K12 | 6454 11164 | 15806 | -0.129 | -0.0668 | No | ||
212 | TRAF7 | 10325 | 15823 | -0.132 | -0.0662 | No | ||
213 | MAPK8 | 6459 | 15826 | -0.132 | -0.0648 | No | ||
214 | GPS2 | 12096 | 16033 | -0.164 | -0.0741 | No | ||
215 | HMOX1 | 18565 | 16404 | -0.243 | -0.0914 | No | ||
216 | UBE2N | 8216 19898 | 16465 | -0.258 | -0.0916 | No | ||
217 | BCL3 | 8654 | 16492 | -0.266 | -0.0900 | No | ||
218 | DAPK2 | 19395 | 16519 | -0.271 | -0.0882 | No | ||
219 | SNF1LK | 23033 | 16536 | -0.277 | -0.0859 | No | ||
220 | MKNK1 | 2504 | 16601 | -0.293 | -0.0859 | No | ||
221 | NUP62 | 9497 | 16635 | -0.305 | -0.0842 | No | ||
222 | DAPK3 | 19932 | 16684 | -0.315 | -0.0831 | No | ||
223 | SOCS1 | 4522 | 16716 | -0.323 | -0.0811 | No | ||
224 | NLK | 5179 5178 | 16855 | -0.362 | -0.0844 | No | ||
225 | ADAM9 | 18910 | 16943 | -0.389 | -0.0846 | No | ||
226 | PPP5C | 17952 | 16955 | -0.393 | -0.0806 | No | ||
227 | DBNL | 20954 | 16960 | -0.394 | -0.0762 | No | ||
228 | VAPA | 22908 | 16971 | -0.398 | -0.0722 | No | ||
229 | UBE2V1 | 12381 | 17023 | -0.419 | -0.0701 | No | ||
230 | ADRB2 | 23422 | 17107 | -0.447 | -0.0694 | No | ||
231 | GSG2 | 20356 | 17117 | -0.452 | -0.0646 | No | ||
232 | PLK2 | 21566 | 17129 | -0.455 | -0.0599 | No | ||
233 | MALT1 | 6274 | 17250 | -0.505 | -0.0606 | No | ||
234 | FLNA | 24129 | 17448 | -0.596 | -0.0644 | No | ||
235 | GADD45B | 19935 | 17459 | -0.605 | -0.0579 | No | ||
236 | IRAK1 | 4916 | 17509 | -0.634 | -0.0532 | No | ||
237 | FADD | 17536 8950 4711 | 17535 | -0.648 | -0.0470 | No | ||
238 | FGF13 | 4720 8963 2627 | 17551 | -0.656 | -0.0402 | No | ||
239 | CHUK | 23665 | 17636 | -0.706 | -0.0366 | No | ||
240 | CD24 | 8711 | 17683 | -0.733 | -0.0306 | No | ||
241 | TRAF5 | 13718 | 17717 | -0.750 | -0.0236 | No | ||
242 | ZDHHC13 | 18233 1936 | 17798 | -0.815 | -0.0185 | No | ||
243 | PIK3CB | 19030 | 17889 | -0.885 | -0.0131 | No | ||
244 | SRPK1 | 23049 | 17977 | -0.952 | -0.0068 | No | ||
245 | MAP4K1 | 18313 | 18098 | -1.095 | -0.0006 | No | ||
246 | ADRA2C | 16869 | 18138 | -1.145 | 0.0106 | No | ||
247 | GPR89A | 7459 12548 | 18240 | -1.323 | 0.0205 | No |