Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos |
| Upregulated in class | transDMpreB |
| GeneSet | PYRIMIDINE_METABOLISM |
| Enrichment Score (ES) | -0.66036135 |
| Normalized Enrichment Score (NES) | -1.3724432 |
| Nominal p-value | 0.037209302 |
| FDR q-value | 0.5355276 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NP | 22027 9597 5273 5274 | 16 | 4.458 | 0.1134 | No | ||
| 2 | DCK | 16808 | 345 | 1.630 | 0.1375 | No | ||
| 3 | RRM2 | 5401 5400 | 461 | 1.431 | 0.1679 | No | ||
| 4 | UCK1 | 10254 5831 10253 | 907 | 0.818 | 0.1649 | No | ||
| 5 | TK2 | 18779 | 2056 | 0.268 | 0.1100 | No | ||
| 6 | RRM1 | 18163 | 2345 | 0.193 | 0.0994 | No | ||
| 7 | POLD1 | 17847 | 2346 | 0.193 | 0.1043 | No | ||
| 8 | NUDT2 | 16239 | 2803 | 0.112 | 0.0826 | No | ||
| 9 | POLB | 9599 | 2898 | 0.101 | 0.0802 | No | ||
| 10 | POLS | 9963 | 3022 | 0.088 | 0.0758 | No | ||
| 11 | UPP1 | 20947 1385 | 3996 | 0.029 | 0.0241 | No | ||
| 12 | POLR2I | 12839 | 4549 | 0.016 | -0.0052 | No | ||
| 13 | CTPS2 | 12060 2571 | 5968 | 0.006 | -0.0814 | No | ||
| 14 | ENTPD1 | 4495 | 7363 | 0.002 | -0.1564 | No | ||
| 15 | DPYD | 15437 | 7773 | 0.001 | -0.1784 | No | ||
| 16 | DPYS | 22305 | 8670 | -0.001 | -0.2267 | No | ||
| 17 | ITPA | 9193 | 8995 | -0.002 | -0.2441 | No | ||
| 18 | POLR2B | 16817 | 9559 | -0.003 | -0.2743 | No | ||
| 19 | POLR2C | 9750 | 11129 | -0.008 | -0.3586 | No | ||
| 20 | AK3L1 | 8564 | 12154 | -0.012 | -0.4135 | No | ||
| 21 | UPB1 | 19988 3389 | 12317 | -0.013 | -0.4219 | No | ||
| 22 | CDA | 15702 | 12412 | -0.013 | -0.4266 | No | ||
| 23 | TXNRD1 | 19923 | 13149 | -0.019 | -0.4658 | No | ||
| 24 | CANT1 | 13304 | 13933 | -0.029 | -0.5072 | No | ||
| 25 | POLQ | 13407 22768 | 14802 | -0.052 | -0.5526 | No | ||
| 26 | NT5E | 19360 18702 | 15289 | -0.078 | -0.5768 | No | ||
| 27 | POLR2A | 5394 | 15899 | -0.143 | -0.6060 | No | ||
| 28 | ECGF1 | 22160 | 16272 | -0.210 | -0.6206 | No | ||
| 29 | POLR2G | 23753 | 17011 | -0.414 | -0.6498 | Yes | ||
| 30 | POLR2K | 9413 | 17083 | -0.439 | -0.6423 | Yes | ||
| 31 | POLRMT | 19705 | 17196 | -0.477 | -0.6362 | Yes | ||
| 32 | POLR2J | 16672 | 17332 | -0.543 | -0.6295 | Yes | ||
| 33 | POLL | 23658 3688 | 17537 | -0.649 | -0.6239 | Yes | ||
| 34 | POLE | 16755 | 17734 | -0.763 | -0.6149 | Yes | ||
| 35 | TYMS | 5810 5809 3606 3598 | 17793 | -0.813 | -0.5972 | Yes | ||
| 36 | POLG | 17789 | 17816 | -0.826 | -0.5772 | Yes | ||
| 37 | DTYMK | 5776 | 17848 | -0.856 | -0.5570 | Yes | ||
| 38 | UNG | 10257 16744 | 17940 | -0.920 | -0.5383 | Yes | ||
| 39 | NT5C | 20151 | 18019 | -1.001 | -0.5169 | Yes | ||
| 40 | POLR2H | 10888 | 18041 | -1.027 | -0.4917 | Yes | ||
| 41 | NT5M | 8345 4175 | 18091 | -1.087 | -0.4665 | Yes | ||
| 42 | TK1 | 1457 10182 5762 | 18157 | -1.175 | -0.4399 | Yes | ||
| 43 | POLD2 | 20537 | 18183 | -1.216 | -0.4101 | Yes | ||
| 44 | DHODH | 7152 | 18220 | -1.285 | -0.3791 | Yes | ||
| 45 | CAD | 16886 | 18241 | -1.324 | -0.3462 | Yes | ||
| 46 | NME2 | 9468 | 18254 | -1.345 | -0.3124 | Yes | ||
| 47 | UMPS | 22606 1760 | 18295 | -1.443 | -0.2776 | Yes | ||
| 48 | NME1 | 9467 | 18350 | -1.540 | -0.2410 | Yes | ||
| 49 | POLR1B | 14857 | 18521 | -2.309 | -0.1910 | Yes | ||
| 50 | DCTD | 18620 | 18522 | -2.310 | -0.1318 | Yes | ||
| 51 | POLR2E | 3325 19699 | 18536 | -2.490 | -0.0687 | Yes | ||
| 52 | CTPS | 2514 15772 | 18563 | -2.849 | 0.0029 | Yes |
