Details for gene set HSA04010_MAPK_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos
Phenotype	phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos
Upregulated in class	transDMproB
GeneSet	HSA04010_MAPK_SIGNALING_PATHWAY
Enrichment Score (ES)	0.6277755
Normalized Enrichment Score (NES)	1.537198
Nominal p-value	0.0
FDR q-value	0.297479
FWER p-Value	0.625

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DUSP6	19891 3399	15	4.550	0.0684	Yes
2	MAPK1	1642 11167	80	2.911	0.1092	Yes
3	PRKCB1	1693 9574	81	2.858	0.1526	Yes
4	MAPK9	1233 20903 1383	85	2.800	0.1950	Yes
5	RRAS2	12431	110	2.587	0.2331	Yes
6	MAPKAPK2	13838	146	2.333	0.2666	Yes
7	CACNA2D1	8676	157	2.291	0.3009	Yes
8	PPM1B	5280 1567 5281	240	1.952	0.3262	Yes
9	RASGRP2	9693	332	1.658	0.3464	Yes
10	MAP4K2	6457	348	1.618	0.3702	Yes
11	DUSP1	23061	416	1.523	0.3897	Yes
12	TGFB1	18332	452	1.452	0.4099	Yes
13	GADD45A	17129	481	1.383	0.4294	Yes
14	MAP3K3	20626	561	1.226	0.4437	Yes
15	DUSP2	14865	619	1.119	0.4577	Yes
16	PRKACB	15140	705	1.014	0.4685	Yes
17	DDIT3	19857	721	0.999	0.4828	Yes
18	RASA1	10174	782	0.936	0.4938	Yes
19	MAP3K5	20079 11166	996	0.734	0.4934	Yes
20	TRAF6	5797 14940	1054	0.682	0.5006	Yes
21	MAP4K3	22887	1118	0.641	0.5070	Yes
22	MAPK14	23313	1184	0.600	0.5125	Yes
23	MAP3K7IP2	19827	1186	0.599	0.5216	Yes
24	NFKB2	23810	1233	0.578	0.5279	Yes
25	CRKL	4560	1245	0.572	0.5360	Yes
26	PPP3CC	21763	1251	0.569	0.5444	Yes
27	RAC2	22217	1257	0.566	0.5527	Yes
28	AKT3	13739 982	1267	0.562	0.5608	Yes
29	MAP3K14	11998	1289	0.549	0.5680	Yes
30	KRAS	9247	1356	0.521	0.5723	Yes
31	PTPN7	11500	1482	0.468	0.5726	Yes
32	PPP3CB	5285	1499	0.461	0.5788	Yes
33	RRAS	18256	1543	0.442	0.5831	Yes
34	RAC1	16302	1568	0.428	0.5883	Yes
35	JUN	15832	1569	0.428	0.5948	Yes
36	MAP4K4	11241	1693	0.381	0.5940	Yes
37	NFKB1	15160	1695	0.381	0.5997	Yes
38	MKNK2	3299 9392	1789	0.349	0.5999	Yes
39	RPS6KA4	23804	1799	0.345	0.6047	Yes
40	CASP3	8693	1817	0.337	0.6089	Yes
41	STK3	7084	1848	0.328	0.6122	Yes
42	RAP1B	10083	1909	0.312	0.6137	Yes
43	STK4	14743	1926	0.308	0.6176	Yes
44	MEF2C	3204 9378	1945	0.302	0.6212	Yes
45	CDC25B	14841	2033	0.276	0.6206	Yes
46	ARRB2	20806	2116	0.251	0.6200	Yes
47	MAP3K1	21348	2190	0.232	0.6195	Yes
48	MAP2K3	20856	2228	0.221	0.6209	Yes
49	SOS2	21049	2262	0.214	0.6223	Yes
50	MAP2K5	19088	2276	0.211	0.6249	Yes
51	MAP3K4	23126	2282	0.210	0.6278	Yes
52	IL1B	14431	2372	0.186	0.6258	No
53	CACNB2	4466 8678	2406	0.180	0.6267	No
54	GNG12	4789	2454	0.170	0.6267	No
55	ACVR1B	4335 22353	2599	0.145	0.6211	No
56	EGF	15169	2619	0.142	0.6222	No
57	GRB2	20149	2736	0.123	0.6178	No
58	CD14	23452	2841	0.108	0.6138	No
59	PAK1	9527	2868	0.104	0.6139	No
60	RASGRP4	6119	3132	0.078	0.6008	No
61	MYC	22465 9435	3151	0.076	0.6010	No
62	FGFR2	1917 4722 1119	3186	0.073	0.6003	No
63	MAPK13	23314	3196	0.072	0.6009	No
64	FOS	21202	3267	0.066	0.5981	No
65	GNA12	9023	3320	0.062	0.5962	No
66	NF1	5165	3443	0.054	0.5903	No
67	ELK4	8895 4664 3937	3449	0.053	0.5909	No
68	PPM1A	5279 9607	3495	0.050	0.5892	No
69	CACNA1F	12054 24393	3737	0.038	0.5766	No
70	FAS	23881 3750	3746	0.038	0.5768	No
71	PDGFRB	23539	3843	0.035	0.5721	No
72	CACNA2D2	7154	3912	0.032	0.5689	No
73	ARRB1	3890 8465 18178 4276	3916	0.032	0.5692	No
74	PDGFA	5237	3931	0.031	0.5689	No
75	DUSP4	18632 3820	3938	0.031	0.5690	No
76	FGF1	1994 23447	4054	0.027	0.5632	No
77	MAP3K7IP1	2193 2171 22419	4071	0.027	0.5627	No
78	MAP3K8	23495	4233	0.022	0.5543	No
79	TRAF2	14657	4330	0.020	0.5494	No
80	PLA2G5	9583	4416	0.019	0.5451	No
81	PLA2G1B	9581	4509	0.017	0.5403	No
82	FGF22	12468 7385	4521	0.017	0.5400	No
83	MAPK3	6458 11170	4552	0.016	0.5386	No
84	TNF	23004	4599	0.016	0.5363	No
85	CACNA1E	4465	4619	0.016	0.5355	No
86	MAPK7	1381 20414	4636	0.015	0.5349	No
87	TGFBR1	16213 10165 5745	4801	0.013	0.5262	No
88	PRKCA	20174	4949	0.012	0.5184	No
89	DUSP7	10661	4966	0.012	0.5177	No
90	CRK	4559 1249	5134	0.011	0.5087	No
91	MAP3K6	16054	5180	0.011	0.5065	No
92	MAP3K10	3831 17916	5288	0.010	0.5008	No
93	FGF21	17830	5463	0.009	0.4915	No
94	FGF9	8966	5506	0.009	0.4893	No
95	DUSP10	4003 14016	5533	0.008	0.4880	No
96	FGFR4	3226	5546	0.008	0.4875	No
97	IL1R2	14265	5549	0.008	0.4875	No
98	CACNA1G	1237 940 20292	5607	0.008	0.4845	No
99	PRKACA	18549 3844	5640	0.008	0.4829	No
100	SOS1	5476	5657	0.008	0.4822	No
101	PPP3R1	9611 489	5824	0.007	0.4732	No
102	MAP3K13	22814	5891	0.007	0.4697	No
103	FGF18	4721 1351	5909	0.007	0.4689	No
104	DUSP16	1004 7699	6041	0.006	0.4619	No
105	FGF4	8964	6302	0.005	0.4478	No
106	PRKX	9619 5290	6327	0.005	0.4466	No
107	CACNG7	13497	6345	0.005	0.4457	No
108	ACVR1C	14585	6349	0.005	0.4456	No
109	PLA2G10	22658	6363	0.005	0.4450	No
110	RASGRP1	5360 14476 9694	6394	0.005	0.4435	No
111	TGFBR2	2994 3001 10167	6464	0.005	0.4398	No
112	PDGFB	22199 2311	6497	0.005	0.4381	No
113	FGF16	24270	6572	0.004	0.4341	No
114	TAOK2	10610 3794	6706	0.004	0.4270	No
115	CDC42	4503 8722 4504 2465	6780	0.004	0.4230	No
116	PLA2G12B	20016	7070	0.003	0.4074	No
117	DUSP8	9493	7186	0.003	0.4011	No
118	MAPT	9420 1347	7406	0.002	0.3893	No
119	CACNB4	4467	7472	0.002	0.3857	No
120	FASLG	13789	7513	0.002	0.3836	No
121	CACNA1H	23077	7540	0.002	0.3822	No
122	AKT2	4365 4366	7867	0.001	0.3645	No
123	MAP2K1IP1	12158	7868	0.001	0.3645	No
124	CACNG4	20176	8000	0.000	0.3574	No
125	RAP1A	8467	8098	0.000	0.3521	No
126	FGF7	8965	8131	0.000	0.3504	No
127	RAC3	20561	8167	0.000	0.3485	No
128	CACNG6	7033	8185	-0.000	0.3475	No
129	DUSP9	24307	8206	-0.000	0.3464	No
130	PLA2G3	20968	8602	-0.001	0.3250	No
131	NR4A1	9099	8658	-0.001	0.3220	No
132	CACNG3	12029	8907	-0.002	0.3085	No
133	PLA2G2A	16017	9066	-0.002	0.3000	No
134	PLA2G4A	13809	9332	-0.003	0.2856	No
135	MAP2K4	20405	9477	-0.003	0.2778	No
136	MAP2K7	6453	9567	-0.003	0.2730	No
137	CACNG8	13498	9835	-0.004	0.2585	No
138	RPS6KA3	8490	9927	-0.004	0.2536	No
139	PPP3CA	1863 5284	10074	-0.004	0.2458	No
140	RPS6KA6	12458	10187	-0.005	0.2397	No
141	CACNG5	1339 20175	10230	-0.005	0.2375	No
142	FGF12	1723 22621	10236	-0.005	0.2373	No
143	EVI1	4689 8926	10259	-0.005	0.2362	No
144	IL1A	4915	10423	-0.005	0.2274	No
145	NFATC4	22002	10475	-0.006	0.2247	No
146	NFATC2	5168 2866	10494	-0.006	0.2238	No
147	MOS	16254	10557	-0.006	0.2205	No
148	NTF5	18248	10797	-0.006	0.2076	No
149	FLNC	4302 8510	10875	-0.007	0.2036	No
150	BDNF	14926 2797	10903	-0.007	0.2022	No
151	PDGFRA	16824	10973	-0.007	0.1985	No
152	MAPK8IP3	11402 23080	11006	-0.007	0.1969	No
153	EGFR	1329 20944	11167	-0.008	0.1883	No
154	FGF11	20383	11245	-0.008	0.1842	No
155	PLA2G2E	16016	11290	-0.008	0.1820	No
156	FGF14	21716 3005 3463	11291	-0.008	0.1821	No
157	FGFR1	3789 8968	11379	-0.008	0.1775	No
158	MAPKAPK5	16387	11527	-0.009	0.1696	No
159	CACNA1B	8673 4462	11626	-0.009	0.1644	No
160	MAPK10	11169	11763	-0.010	0.1572	No
161	RPS6KA2	9759 9758	11842	-0.010	0.1531	No
162	CACNB3	22373 8679	11877	-0.011	0.1514	No
163	MRAS	9409	11948	-0.011	0.1478	No
164	RPS6KA5	2076 21005	12243	-0.012	0.1320	No
165	PTPRR	3436 19876	12264	-0.013	0.1311	No
166	FGF5	16785	12288	-0.013	0.1300	No
167	CACNA1D	4464 8675	12388	-0.013	0.1248	No
168	PPP3R2	9612	12427	-0.013	0.1230	No
169	FGF20	18892	12484	-0.014	0.1201	No
170	CACNA1A	4461	12498	-0.014	0.1196	No
171	NTRK1	15299	12524	-0.014	0.1185	No
172	NGFB	15476	12701	-0.015	0.1092	No
173	FGF8	23656	12742	-0.016	0.1072	No
174	PLA2G2D	16018	12804	-0.016	0.1041	No
175	FGFR3	8969 3566	12834	-0.016	0.1028	No
176	NTRK2	9491	13241	-0.020	0.0810	No
177	FGF10	4719 8962	13261	-0.020	0.0803	No
178	AKT1	8568	13355	-0.021	0.0755	No
179	RASGRF1	3050 19357	13397	-0.021	0.0736	No
180	GADD45G	21637	13491	-0.022	0.0689	No
181	TGFB3	10161	13520	-0.023	0.0677	No
182	DAXX	23290	13619	-0.024	0.0628	No
183	FGF2	15608	13664	-0.025	0.0608	No
184	NTF3	16991	13671	-0.025	0.0608	No
185	IKBKG	2570 2562 4908	13789	-0.027	0.0548	No
186	CACNA1C	1158 1166 24464 4463 8674	13840	-0.028	0.0525	No
187	DUSP14	12124	14289	-0.036	0.0287	No
188	PTPN5	17817	14302	-0.037	0.0286	No
189	CACNA2D3	8677	14394	-0.039	0.0243	No
190	MAPK8IP2	77	14498	-0.042	0.0193	No
191	MAPK11	2264 9618 22163	14587	-0.045	0.0152	No
192	PLA2G6	22209	14608	-0.045	0.0148	No
193	FGF23	17275	14683	-0.047	0.0115	No
194	FGF17	21757	14703	-0.048	0.0112	No
195	TNFRSF1A	1181 10206	14806	-0.052	0.0064	No
196	ATF2	4418 2759	14826	-0.053	0.0062	No
197	MAP3K2	11165	14854	-0.054	0.0055	No
198	RASGRF2	21397	14906	-0.056	0.0036	No
199	IL1R1	14264 3987	14939	-0.057	0.0028	No
200	RAF1	17035	15064	-0.065	-0.0030	No
201	TGFB2	5743	15106	-0.067	-0.0042	No
202	DUSP3	1358 13022	15107	-0.067	-0.0032	No
203	RASA2	4329	15110	-0.068	-0.0023	No
204	MAX	21034	15233	-0.075	-0.0078	No
205	MAP2K6	20614 1414	15246	-0.076	-0.0073	No
206	CACNG1	20177	15255	-0.077	-0.0065	No
207	RPS6KA1	15725	15263	-0.077	-0.0057	No
208	MAP3K7	16255	15267	-0.077	-0.0047	No
209	PAK2	10310 5875	15410	-0.087	-0.0111	No
210	SRF	22961 1597	15416	-0.087	-0.0101	No
211	PLA2G2F	15700	15466	-0.091	-0.0114	No
212	CACNB1	1443 1304	15529	-0.097	-0.0133	No
213	FGF3	17997	15532	-0.097	-0.0119	No
214	STMN1	9261	15569	-0.101	-0.0123	No
215	MAP3K12	6454 11164	15806	-0.129	-0.0232	No
216	MAPK8	6459	15826	-0.132	-0.0222	No
217	MAP2K1	19082	15878	-0.140	-0.0229	No
218	CACNA1S	14111	16028	-0.163	-0.0285	No
219	HRAS	4868	16140	-0.184	-0.0318	No
220	RASGRP3	10767	16207	-0.196	-0.0324	No
221	NRAS	5191	16367	-0.233	-0.0375	No
222	MAP2K2	19933	16484	-0.264	-0.0398	No
223	ATF4	22417 2239	16600	-0.293	-0.0416	No
224	MKNK1	2504	16601	-0.293	-0.0371	No
225	MAPKAPK3	19003	16817	-0.350	-0.0435	No
226	NLK	5179 5178	16855	-0.362	-0.0400	No
227	TP53	20822	16897	-0.375	-0.0365	No
228	PPP5C	17952	16955	-0.393	-0.0337	No
229	FLNB	13742	17243	-0.502	-0.0416	No
230	IKBKB	4907	17370	-0.562	-0.0399	No
231	FLNA	24129	17448	-0.596	-0.0351	No
232	GADD45B	19935	17459	-0.605	-0.0264	No
233	MAPK12	2182 2215 22164	17503	-0.632	-0.0192	No
234	FGF13	4720 8963 2627	17551	-0.656	-0.0117	No
235	CHUK	23665	17636	-0.706	-0.0056	No
236	MAP4K1	18313	18098	-1.095	-0.0140	No
237	ECSIT	11248	18238	-1.322	-0.0015	No
238	PLA2G12A	1782 7281 1839	18298	-1.446	0.0173	No