Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB.phenotype_transDMproB_versus_transDMpreB.cls #transDMproB_versus_transDMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_transDMpreB.cls#transDMproB_versus_transDMpreB_repos |
| Upregulated in class | transDMpreB |
| GeneSet | REACTOME_MRNA_SPLICING |
| Enrichment Score (ES) | -0.72247326 |
| Normalized Enrichment Score (NES) | -1.5993544 |
| Nominal p-value | 0.0023696683 |
| FDR q-value | 0.040601052 |
| FWER p-Value | 0.414 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | SNRPA1 | 1373 18216 | 381 | 1.570 | 0.0383 | No | ||
| 2 | CD2BP2 | 17621 | 1689 | 0.383 | -0.0178 | No | ||
| 3 | SFRS7 | 22889 | 1898 | 0.314 | -0.0172 | No | ||
| 4 | THOC4 | 5710 10114 | 2148 | 0.243 | -0.0215 | No | ||
| 5 | PCBP2 | 9533 | 2156 | 0.241 | -0.0129 | No | ||
| 6 | CSTF2 | 24257 | 3071 | 0.083 | -0.0590 | No | ||
| 7 | SFRS3 | 5428 23312 | 3158 | 0.076 | -0.0608 | No | ||
| 8 | RBMX | 5367 9708 | 3204 | 0.071 | -0.0606 | No | ||
| 9 | SF4 | 18593 | 3404 | 0.056 | -0.0692 | No | ||
| 10 | U2AF2 | 5813 5812 5814 | 3857 | 0.034 | -0.0923 | No | ||
| 11 | CSTF3 | 10449 6002 | 4328 | 0.020 | -0.1169 | No | ||
| 12 | SF3B1 | 13954 | 4374 | 0.019 | -0.1186 | No | ||
| 13 | POLR2I | 12839 | 4549 | 0.016 | -0.1273 | No | ||
| 14 | RNPS1 | 9730 23361 | 7696 | 0.001 | -0.2969 | No | ||
| 15 | RBM5 | 13507 3016 | 8413 | -0.001 | -0.3355 | No | ||
| 16 | PCF11 | 121 | 8517 | -0.001 | -0.3410 | No | ||
| 17 | POLR2B | 16817 | 9559 | -0.003 | -0.3970 | No | ||
| 18 | SNRPE | 9843 | 10124 | -0.005 | -0.4272 | No | ||
| 19 | SNRPB2 | 5470 | 10690 | -0.006 | -0.4575 | No | ||
| 20 | PABPN1 | 12018 | 10865 | -0.007 | -0.4666 | No | ||
| 21 | POLR2C | 9750 | 11129 | -0.008 | -0.4805 | No | ||
| 22 | PAPOLA | 5261 9585 | 11405 | -0.009 | -0.4950 | No | ||
| 23 | SMC1A | 2572 24225 6279 10780 | 13661 | -0.025 | -0.6156 | No | ||
| 24 | DNAJC8 | 12712 | 14910 | -0.056 | -0.6808 | No | ||
| 25 | SFRS1 | 8492 | 15175 | -0.071 | -0.6923 | No | ||
| 26 | CCAR1 | 7454 | 15735 | -0.120 | -0.7180 | Yes | ||
| 27 | SF3B2 | 23974 | 15809 | -0.129 | -0.7171 | Yes | ||
| 28 | SRRM1 | 6958 | 15872 | -0.139 | -0.7152 | Yes | ||
| 29 | POLR2A | 5394 | 15899 | -0.143 | -0.7112 | Yes | ||
| 30 | SFRS2 | 9807 20136 | 15923 | -0.146 | -0.7070 | Yes | ||
| 31 | NFX1 | 2475 | 15957 | -0.151 | -0.7031 | Yes | ||
| 32 | CSTF1 | 12515 | 16090 | -0.175 | -0.7037 | Yes | ||
| 33 | PRPF8 | 20780 1371 | 16105 | -0.178 | -0.6978 | Yes | ||
| 34 | SFRS9 | 16731 | 16235 | -0.203 | -0.6971 | Yes | ||
| 35 | SF3B4 | 22269 | 16255 | -0.207 | -0.6904 | Yes | ||
| 36 | NUDT21 | 12665 | 16345 | -0.226 | -0.6867 | Yes | ||
| 37 | PTBP1 | 5303 | 16386 | -0.238 | -0.6799 | Yes | ||
| 38 | SNRPA | 7007 11992 7008 | 16440 | -0.252 | -0.6734 | Yes | ||
| 39 | SNRPG | 12622 | 16463 | -0.258 | -0.6649 | Yes | ||
| 40 | MAGOH | 2386 16148 | 16529 | -0.275 | -0.6581 | Yes | ||
| 41 | FUS | 6135 | 16575 | -0.287 | -0.6498 | Yes | ||
| 42 | SF3A3 | 16091 | 16675 | -0.313 | -0.6434 | Yes | ||
| 43 | PCBP1 | 17085 | 16841 | -0.359 | -0.6388 | Yes | ||
| 44 | SNRPB | 9842 5469 2736 | 16845 | -0.360 | -0.6255 | Yes | ||
| 45 | SF3A2 | 19938 | 16967 | -0.396 | -0.6172 | Yes | ||
| 46 | POLR2G | 23753 | 17011 | -0.414 | -0.6040 | Yes | ||
| 47 | SF3A1 | 7450 | 17019 | -0.417 | -0.5887 | Yes | ||
| 48 | SNRPF | 7645 | 17025 | -0.419 | -0.5733 | Yes | ||
| 49 | SFRS6 | 14751 | 17246 | -0.503 | -0.5663 | Yes | ||
| 50 | GTF2F1 | 13599 | 17263 | -0.510 | -0.5480 | Yes | ||
| 51 | POLR2J | 16672 | 17332 | -0.543 | -0.5314 | Yes | ||
| 52 | SNRPD3 | 12514 | 17340 | -0.547 | -0.5112 | Yes | ||
| 53 | PHF5A | 22194 | 17362 | -0.559 | -0.4914 | Yes | ||
| 54 | SNRPD2 | 8412 | 17505 | -0.632 | -0.4754 | Yes | ||
| 55 | CPSF1 | 22241 | 17547 | -0.654 | -0.4531 | Yes | ||
| 56 | SF3B3 | 18746 | 17567 | -0.669 | -0.4290 | Yes | ||
| 57 | SFRS5 | 9808 2062 | 17659 | -0.716 | -0.4071 | Yes | ||
| 58 | U2AF1 | 8431 | 17718 | -0.750 | -0.3821 | Yes | ||
| 59 | YBX1 | 5929 2389 | 17736 | -0.765 | -0.3544 | Yes | ||
| 60 | PRPF4 | 7655 12845 | 17806 | -0.820 | -0.3274 | Yes | ||
| 61 | NCBP2 | 12643 | 17873 | -0.871 | -0.2983 | Yes | ||
| 62 | EFTUD2 | 1219 20203 | 17956 | -0.931 | -0.2678 | Yes | ||
| 63 | POLR2H | 10888 | 18041 | -1.027 | -0.2339 | Yes | ||
| 64 | GTF2F2 | 21750 | 18128 | -1.139 | -0.1958 | Yes | ||
| 65 | DHX9 | 8845 4608 3948 | 18361 | -1.568 | -0.1496 | Yes | ||
| 66 | TXNL4A | 6567 11329 | 18451 | -1.865 | -0.0845 | Yes | ||
| 67 | POLR2E | 3325 19699 | 18536 | -2.490 | 0.0043 | Yes |
