Details for gene set REACTOME_REGULATION_OF_INSULIN

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB
Phenotype	phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB
Upregulated in class	transDMproB
GeneSet	REACTOME_REGULATION_OF_INSULIN_SECRETION
Enrichment Score (ES)	0.6985235
Normalized Enrichment Score (NES)	1.535428
Nominal p-value	0.003220612
FDR q-value	0.69759005
FWER p-Value	0.977

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NDUFC1	7287 12339	0	5.436	0.2514	Yes
2	OGDH	9502 1412	76	1.582	0.3205	Yes
3	NDUFB5	12277	229	0.698	0.3446	Yes
4	NDUFA6	12473	275	0.620	0.3708	Yes
5	ATP5E	14321	326	0.541	0.3931	Yes
6	COX6B1	4283 8479	445	0.445	0.4073	Yes
7	COX7A2L	9819	525	0.401	0.4216	Yes
8	UQCRH	12378	654	0.356	0.4311	Yes
9	NDUFA11	12832	657	0.354	0.4474	Yes
10	CS	19839	668	0.349	0.4630	Yes
11	SDHD	19125	687	0.345	0.4780	Yes
12	NDUFA1	24170	765	0.323	0.4888	Yes
13	UQCRB	12545	779	0.320	0.5029	Yes
14	MDH2	9399	849	0.305	0.5132	Yes
15	COX6C	8775	873	0.300	0.5258	Yes
16	NDUFA7	12347	888	0.298	0.5389	Yes
17	ATP5I	8637	905	0.294	0.5516	Yes
18	ATP5F1	15212	982	0.282	0.5605	Yes
19	NDUFB3	12362	1009	0.275	0.5718	Yes
20	NDUFA3	18410	1107	0.257	0.5785	Yes
21	CYCS	8821	1127	0.254	0.5892	Yes
22	ATP5A1	23505	1134	0.252	0.6005	Yes
23	ETFB	18279	1164	0.248	0.6104	Yes
24	COX7B	7260	1233	0.233	0.6175	Yes
25	NDUFS4	9452 5157 3173	1272	0.228	0.6260	Yes
26	PFKFB3	2748	1365	0.216	0.6311	Yes
27	NDUFB8	7418	1441	0.205	0.6365	Yes
28	NDUFC2	18183	1482	0.199	0.6436	Yes
29	NDUFA2	9450	1526	0.192	0.6501	Yes
30	NDUFB2	7542	1536	0.191	0.6585	Yes
31	ETFA	4292 8495 3155	1598	0.181	0.6635	Yes
32	NDUFA9	12288	1608	0.179	0.6713	Yes
33	NDUFS8	23950	1700	0.169	0.6742	Yes
34	NDUFA4	9451	1786	0.159	0.6769	Yes
35	NDUFB7	12429	1797	0.158	0.6837	Yes
36	ATP5H	12948	1804	0.157	0.6906	Yes
37	NDUFS2	4089 13760	1978	0.135	0.6875	Yes
38	ATP5O	22539	1996	0.133	0.6927	Yes
39	DLAT	19123	2003	0.132	0.6985	Yes
40	COX7C	8776	2137	0.118	0.6968	No
41	NDUFB10	23084	2337	0.100	0.6907	No
42	NDUFA8	14605	2559	0.085	0.6827	No
43	ATP5J2	12186	2580	0.084	0.6855	No
44	COX4I1	18444	2649	0.079	0.6854	No
45	SDHB	2348 12566 14880	2862	0.065	0.6770	No
46	COX8A	8777	2965	0.060	0.6743	No
47	DLST	8131	3479	0.040	0.6484	No
48	IQGAP1	6619	3500	0.039	0.6491	No
49	NDUFA5	1076 7544	3509	0.039	0.6505	No
50	PGK1	9557 5244	3674	0.034	0.6432	No
51	UQCRFS1	21499	3972	0.028	0.6285	No
52	ATP5C1	8635	4941	0.016	0.5769	No
53	SUCLG1	17409 1059	5527	0.012	0.5459	No
54	PRKACB	15140	6469	0.008	0.4954	No
55	SYT5	17986	6539	0.007	0.4920	No
56	GNAS	9025 2963 2752	6792	0.007	0.4787	No
57	RAP1A	8467	6804	0.007	0.4784	No
58	GCG	14578	6990	0.006	0.4687	No
59	PFKFB1	9552	7348	0.005	0.4497	No
60	NDUFB4	22596 7541	7629	0.004	0.4348	No
61	ABCC8	9941 11649	7713	0.004	0.4305	No
62	UQCR	12382	7936	0.004	0.4186	No
63	GLP1R	23304	8259	0.003	0.4014	No
64	SDHA	12436	8271	0.003	0.4009	No
65	NDUFS7	19946	8476	0.002	0.3900	No
66	ATP5J	880 22555	8543	0.002	0.3866	No
67	PDHX	14510	8609	0.002	0.3832	No
68	NDUFS1	13940	10638	-0.002	0.2737	No
69	ADRA2A	4355	10975	-0.002	0.2557	No
70	PDHB	12670 7548	11756	-0.004	0.2137	No
71	PRKAR2B	5288 2107	12592	-0.006	0.1689	No
72	UQCRC2	18102	13373	-0.008	0.1272	No
73	IDH3A	19447	13566	-0.009	0.1172	No
74	KCNJ11	17822	13725	-0.010	0.1091	No
75	CHRM3	21547	14061	-0.012	0.0916	No
76	FFAR1	10583	14336	-0.013	0.0774	No
77	UQCRC1	10259	14484	-0.014	0.0701	No
78	PFKFB2	4116 5242	14566	-0.015	0.0664	No
79	SLC2A2	15623 1880 1855	14974	-0.019	0.0453	No
80	NDUFAB1	7667	15305	-0.024	0.0286	No
81	COX6A1	8774 4553	16268	-0.060	-0.0206	No
82	IDH3G	24132	16333	-0.064	-0.0211	No
83	ATP5B	19846	16374	-0.067	-0.0201	No
84	ATP5G1	8636	16531	-0.077	-0.0250	No
85	PDHA1	24020	16635	-0.087	-0.0265	No
86	COX5A	19431	16647	-0.088	-0.0230	No
87	PRKCA	20174	16649	-0.088	-0.0190	No
88	DLD	2097 21090	16671	-0.090	-0.0160	No
89	ATP5D	19949	16740	-0.097	-0.0152	No
90	NDUFV1	23953	16742	-0.097	-0.0107	No
91	IDH3B	9299	16756	-0.099	-0.0069	No
92	ETFDH	15313	16787	-0.102	-0.0038	No
93	PKM2	3642 9573	16872	-0.110	-0.0033	No
94	NDUFS5	9296	16878	-0.110	0.0016	No
95	COX5B	4552	16962	-0.121	0.0027	No
96	MARCKS	9331	17100	-0.139	0.0017	No
97	CYC1	12348	17113	-0.141	0.0076	No
98	TPI1	5795 10212	17955	-0.325	-0.0228	No
99	NDUFS3	7553 12683	18145	-0.404	-0.0144	No
100	VAMP2	20826	18175	-0.423	0.0037	No
101	NDUFA10	7420	18192	-0.435	0.0229	No