Details for gene set REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_LMproB.phenotype_transDMproB_versus_LMproB.cls #transDMproB_versus_LMproB
Phenotype	phenotype_transDMproB_versus_LMproB.cls#transDMproB_versus_LMproB
Upregulated in class	LMproB
GeneSet	REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR
Enrichment Score (ES)	-0.8669254
Normalized Enrichment Score (NES)	-1.4512172
Nominal p-value	0.058295965
FDR q-value	1.0
FWER p-Value	1.0

Fig 1: Enrichment plot: REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	HRAS	4868	3102	0.053	-0.1454	No
2	RASGRF2	21397	4946	0.016	-0.2383	No
3	NEFL	9459	12909	-0.007	-0.6635	No
4	CAMK2G	21905	14433	-0.014	-0.7398	No
5	CALM1	21184	14639	-0.015	-0.7447	No
6	GRIN2D	9042	14730	-0.016	-0.7431	No
7	ACTN2	21545	15303	-0.024	-0.7642	No
8	RASGRF1	3050 19357	16205	-0.056	-0.7903	Yes
9	CAMK2B	20536	17631	-0.233	-0.7743	Yes
10	AKAP9	16604 16603 4150 8303	18585	-2.077	0.0017	Yes

Fig 2: REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR
Blue-Pink O' Gram in the Space of the Analyzed GeneSet

Fig 3: REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR: Random ES distribution
Gene set null distribution of ES for REACTOME_RAS_ACTIVATION_UOPN_CA2__INFUX_THROUGH_NMDA_RECEPTOR