Details for gene set HSA04810_REGULATION_OF_ACTIN

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos
Phenotype	phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos
Upregulated in class	transDMproB
GeneSet	HSA04810_REGULATION_OF_ACTIN_CYTOSKELETON
Enrichment Score (ES)	0.62954473
Normalized Enrichment Score (NES)	1.5307636
Nominal p-value	0.0
FDR q-value	0.14475422
FWER p-Value	0.75

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MYH9	2252 2244	4	6.155	0.1093	Yes
2	TIAM1	22547	106	2.676	0.1515	Yes
3	MAPK1	1642 11167	108	2.667	0.1989	Yes
4	RRAS2	12431	109	2.666	0.2463	Yes
5	PIK3CG	6635	176	2.268	0.2831	Yes
6	MYLC2PL	16670	196	2.203	0.3213	Yes
7	FGF13	4720 8963 2627	450	1.532	0.3348	Yes
8	MYLK	22778 4213	547	1.366	0.3539	Yes
9	MYLPF	18069	650	1.191	0.3696	Yes
10	SLC9A1	16053	703	1.103	0.3864	Yes
11	CYFIP1	9814	718	1.089	0.4051	Yes
12	VAV1	23173	746	1.053	0.4223	Yes
13	RAC2	22217	803	0.996	0.4370	Yes
14	LIMK2	9278 1296	857	0.943	0.4509	Yes
15	WASF2	6326	953	0.865	0.4612	Yes
16	WAS	24193	958	0.862	0.4763	Yes
17	WASL	17203	963	0.859	0.4914	Yes
18	CYFIP2	20485 8045	1018	0.819	0.5030	Yes
19	SCIN	21079	1024	0.816	0.5173	Yes
20	PAK4	17909	1147	0.717	0.5234	Yes
21	ARPC3	12109	1198	0.682	0.5329	Yes
22	RRAS	18256	1216	0.672	0.5439	Yes
23	VCL	22083	1251	0.653	0.5537	Yes
24	ARHGEF6	13297 13104	1312	0.617	0.5614	Yes
25	IQGAP1	6619	1553	0.499	0.5573	Yes
26	RDX	9712 5371	1562	0.495	0.5656	Yes
27	ITGAL	9187	1625	0.469	0.5706	Yes
28	PIP5K1A	23708	1642	0.461	0.5780	Yes
29	ROCK1	5386	1659	0.454	0.5852	Yes
30	KRAS	9247	1683	0.444	0.5918	Yes
31	ARPC5L	15017	1775	0.401	0.5940	Yes
32	CRKL	4560	1800	0.391	0.5997	Yes
33	SOS2	21049	1883	0.362	0.6017	Yes
34	PIK3CD	9563	1939	0.342	0.6048	Yes
35	ROCK2	21309 5387	1969	0.334	0.6092	Yes
36	ARPC2	14225	2033	0.314	0.6114	Yes
37	GNG12	4789	2082	0.298	0.6141	Yes
38	GNA13	20617	2135	0.285	0.6163	Yes
39	RAC1	16302	2149	0.281	0.6206	Yes
40	PPP1CA	9608 3756 914 909	2257	0.252	0.6193	Yes
41	EGF	15169	2310	0.241	0.6207	Yes
42	CSK	8805	2369	0.230	0.6217	Yes
43	PIP5K1B	5251 1841	2416	0.219	0.6231	Yes
44	ITGB2	19978	2429	0.216	0.6263	Yes
45	MAPK3	6458 11170	2440	0.214	0.6295	Yes
46	ITGA5	22105	2740	0.146	0.6159	No
47	FGD1	24228	2792	0.137	0.6156	No
48	LIMK1	16350	2800	0.137	0.6177	No
49	PAK1	9527	2858	0.127	0.6168	No
50	CD14	23452	2861	0.126	0.6190	No
51	ITGB1	3872 18411	2943	0.113	0.6166	No
52	RAF1	17035	3038	0.101	0.6133	No
53	ITGAV	4931	3093	0.096	0.6121	No
54	GSN	2784	3156	0.090	0.6103	No
55	MAP2K1	19082	3174	0.087	0.6109	No
56	FGFR2	1917 4722 1119	3240	0.081	0.6088	No
57	PDGFRB	23539	3339	0.072	0.6048	No
58	ARHGEF1	1952 18343 3996	3364	0.069	0.6047	No
59	PFN3	7968	3402	0.066	0.6039	No
60	MYL2	16713	3500	0.059	0.5997	No
61	ARAF	24367	3602	0.052	0.5952	No
62	F2	14524	3648	0.049	0.5936	No
63	GNA12	9023	3653	0.049	0.5943	No
64	ITGA6	4930	3674	0.048	0.5940	No
65	CFL2	2155 21069	3732	0.045	0.5917	No
66	SSH2	6202	3751	0.044	0.5915	No
67	ACTN4	17905 1798 1983	3815	0.041	0.5889	No
68	ITGAM	9188	3824	0.041	0.5891	No
69	PDGFA	5237	3830	0.040	0.5896	No
70	SSH1	10540	3858	0.039	0.5888	No
71	ITGA10	15493	3899	0.038	0.5873	No
72	MYH10	8077	3952	0.035	0.5851	No
73	MYL9	14767 2659	4114	0.029	0.5769	No
74	ARPC4	12642	4293	0.024	0.5677	No
75	FGF18	4721 1351	4370	0.022	0.5640	No
76	ITGAE	20791 1481 1397 1380 1278 1238 1359	4393	0.021	0.5631	No
77	ITGA2B	9186	4503	0.019	0.5576	No
78	PIK3R5	11507	4539	0.018	0.5560	No
79	CHRM3	21547	4622	0.017	0.5519	No
80	ABI2	4037 6830	4664	0.016	0.5499	No
81	SOS1	5476	4722	0.015	0.5471	No
82	PXN	5339 3573	4852	0.013	0.5403	No
83	CRK	4559 1249	4892	0.013	0.5384	No
84	PIK3R1	3170	4940	0.013	0.5361	No
85	RAC3	20561	4987	0.012	0.5338	No
86	CDC42	4503 8722 4504 2465	5208	0.010	0.5221	No
87	FGF4	8964	5376	0.009	0.5132	No
88	VAV2	5848 2670	5455	0.008	0.5091	No
89	TMSB4X	24005	5732	0.007	0.4943	No
90	BDKRB2	21163	5912	0.006	0.4847	No
91	MYL7	9437	5962	0.006	0.4821	No
92	FGF21	17830	6170	0.005	0.4710	No
93	FGF1	1994 23447	6176	0.005	0.4708	No
94	ITGA11	6677 11449	6249	0.005	0.4670	No
95	BAIAP2	449 4236	6433	0.004	0.4571	No
96	APC	4396 2022	6508	0.004	0.4532	No
97	PDGFB	22199 2311	6629	0.003	0.4468	No
98	ITGAX	18058	6630	0.003	0.4468	No
99	FGF16	24270	6721	0.003	0.4420	No
100	ITGA3	20284	6741	0.003	0.4410	No
101	ITGB6	14581 2809	6977	0.002	0.4283	No
102	CHRM2	10840	7580	0.001	0.3957	No
103	PIK3CA	9562	7760	0.001	0.3860	No
104	FGF7	8965	7875	0.000	0.3798	No
105	FGF14	21716 3005 3463	8086	-0.000	0.3684	No
106	FGF5	16785	8104	-0.000	0.3675	No
107	FGFR1	3789 8968	8129	-0.000	0.3662	No
108	PIP5K1C	5250 19929	8142	-0.000	0.3656	No
109	ITGA4	4929	8201	-0.001	0.3624	No
110	CHRM4	14945	8268	-0.001	0.3589	No
111	PAK3	9528	8538	-0.001	0.3443	No
112	MRAS	9409	8608	-0.001	0.3406	No
113	ITGA8	14685	8651	-0.002	0.3383	No
114	ARHGEF7	3823	8994	-0.002	0.3198	No
115	CHRM5	10038	9168	-0.003	0.3105	No
116	MOS	16254	9303	-0.003	0.3033	No
117	PAK7	14417	9324	-0.003	0.3023	No
118	ITGA7	19835	9405	-0.003	0.2980	No
119	ITGB5	4932	9771	-0.004	0.2783	No
120	FGF8	23656	9836	-0.005	0.2749	No
121	FGF12	1723 22621	9991	-0.005	0.2666	No
122	PPP1CB	5282 3529 3504	10127	-0.005	0.2594	No
123	ARHGEF12	19156	10291	-0.006	0.2507	No
124	ACTN2	21545	10336	-0.006	0.2484	No
125	TIAM2	10759	10533	-0.007	0.2379	No
126	MYH14	17845	10559	-0.007	0.2366	No
127	FGF11	20383	10692	-0.007	0.2296	No
128	NCKAP1	6947	10745	-0.007	0.2269	No
129	FGF10	4719 8962	10747	-0.007	0.2270	No
130	FGD3	11399	10867	-0.008	0.2207	No
131	CHRM1	23943	11348	-0.009	0.1948	No
132	APC2	10704	11483	-0.010	0.1877	No
133	WASF1	13514	11763	-0.011	0.1728	No
134	PFN2	15337 1818	11816	-0.012	0.1702	No
135	FGF20	18892	11825	-0.012	0.1699	No
136	PDGFRA	16824	11924	-0.012	0.1649	No
137	FGFR3	8969 3566	12054	-0.013	0.1581	No
138	FGF17	21757	12265	-0.014	0.1470	No
139	FGF22	12468 7385	12479	-0.016	0.1357	No
140	FGF9	8966	12523	-0.016	0.1337	No
141	EGFR	1329 20944	12610	-0.017	0.1293	No
142	FGFR4	3226	12709	-0.018	0.1243	No
143	BDKRB1	19418	12963	-0.020	0.1109	No
144	ITGB4	9669 159	12984	-0.021	0.1102	No
145	FGF2	15608	13003	-0.021	0.1096	No
146	ARPC5	12580 7487	13159	-0.023	0.1016	No
147	RHOA	8624 4409 4410	13271	-0.024	0.0960	No
148	PIP5K3	14234	13388	-0.026	0.0902	No
149	SSH3	3709 10890	13660	-0.030	0.0760	No
150	FN1	4091 4094 971 13929	13809	-0.033	0.0686	No
151	ACTN3	23967 8540	14013	-0.037	0.0582	No
152	FGF3	17997	14667	-0.058	0.0239	No
153	VAV3	1774 1848 15443	14719	-0.060	0.0222	No
154	FGF23	17275	14821	-0.065	0.0179	No
155	PPP1R12A	3354 19886	15021	-0.076	0.0084	No
156	ITGA9	19280	15104	-0.082	0.0054	No
157	ITGB3	20631	15630	-0.137	-0.0206	No
158	ARPC1B	3512 8628	15653	-0.140	-0.0193	No
159	MAP2K2	19933	15726	-0.151	-0.0205	No
160	MSN	5122	15878	-0.178	-0.0255	No
161	PIK3R2	18850	15900	-0.181	-0.0234	No
162	PAK2	10310 5875	16141	-0.223	-0.0325	No
163	DIAPH3	7117	16169	-0.229	-0.0298	No
164	F2R	21386	16204	-0.237	-0.0275	No
165	NRAS	5191	16222	-0.243	-0.0241	No
166	PFN4	11798	16492	-0.308	-0.0332	No
167	HRAS	4868	16569	-0.329	-0.0314	No
168	ARPC1A	3541 16628 3519	16824	-0.405	-0.0380	No
169	BCAR1	18741	17079	-0.500	-0.0429	No
170	PPP1CC	9609 5283	17139	-0.524	-0.0368	No
171	PFN1	9555	17219	-0.559	-0.0311	No
172	CFL1	4516	17480	-0.687	-0.0330	No
173	ITGB7	22112	17580	-0.749	-0.0250	No
174	PIK3R3	5248	17847	-0.935	-0.0228	No
175	PIK3CB	19030	17997	-1.070	-0.0118	No
176	PTK2	22271	18532	-2.547	0.0046	No