Details for gene set HSA04010_MAPK_SIGNALING

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos
Phenotype	phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos
Upregulated in class	transDMproB
GeneSet	HSA04010_MAPK_SIGNALING_PATHWAY
Enrichment Score (ES)	0.6150473
Normalized Enrichment Score (NES)	1.5331838
Nominal p-value	0.0
FDR q-value	0.15083128
FWER p-Value	0.735

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DUSP6	19891 3399	19	4.580	0.0588	Yes
2	PRKCB1	1693 9574	42	3.635	0.1051	Yes
3	MAPK9	1233 20903 1383	89	2.817	0.1394	Yes
4	MAPK1	1642 11167	108	2.667	0.1733	Yes
5	RRAS2	12431	109	2.666	0.2081	Yes
6	MAPKAPK2	13838	165	2.313	0.2354	Yes
7	MAP4K2	6457	210	2.155	0.2611	Yes
8	RASGRP2	9693	284	1.912	0.2821	Yes
9	MAP3K7IP1	2193 2171 22419	444	1.544	0.2937	Yes
10	FGF13	4720 8963 2627	450	1.532	0.3134	Yes
11	TGFB1	18332	479	1.483	0.3313	Yes
12	MAP3K3	20626	496	1.448	0.3493	Yes
13	GADD45A	17129	540	1.376	0.3649	Yes
14	CACNA2D1	8676	546	1.366	0.3825	Yes
15	PPM1B	5280 1567 5281	575	1.325	0.3983	Yes
16	MAP3K14	11998	645	1.197	0.4102	Yes
17	PRKACB	15140	668	1.157	0.4241	Yes
18	RASA1	10174	698	1.106	0.4370	Yes
19	DDIT3	19857	742	1.063	0.4486	Yes
20	NFKB2	23810	744	1.056	0.4623	Yes
21	DUSP1	23061	755	1.046	0.4754	Yes
22	RAC2	22217	803	0.996	0.4859	Yes
23	MAP3K7IP2	19827	816	0.979	0.4980	Yes
24	MAPK14	23313	872	0.931	0.5072	Yes
25	DUSP2	14865	1051	0.797	0.5079	Yes
26	MAP3K5	20079 11166	1088	0.768	0.5160	Yes
27	PTPN7	11500	1144	0.719	0.5224	Yes
28	MAP4K3	22887	1158	0.707	0.5310	Yes
29	RRAS	18256	1216	0.672	0.5366	Yes
30	MEF2C	3204 9378	1283	0.629	0.5413	Yes
31	MAP3K1	21348	1290	0.626	0.5491	Yes
32	TP53	20822	1359	0.593	0.5532	Yes
33	MKNK2	3299 9392	1390	0.578	0.5591	Yes
34	RPS6KA4	23804	1464	0.544	0.5622	Yes
35	STK4	14743	1551	0.500	0.5641	Yes
36	TRAF6	5797 14940	1581	0.489	0.5689	Yes
37	PPM1A	5279 9607	1677	0.448	0.5696	Yes
38	KRAS	9247	1683	0.444	0.5751	Yes
39	PPP3CC	21763	1709	0.428	0.5793	Yes
40	MAP4K4	11241	1759	0.408	0.5820	Yes
41	PPP3CB	5285	1794	0.394	0.5853	Yes
42	CRKL	4560	1800	0.391	0.5901	Yes
43	SOS2	21049	1883	0.362	0.5904	Yes
44	NFKB1	15160	1890	0.360	0.5948	Yes
45	AKT3	13739 982	1896	0.357	0.5992	Yes
46	GRB2	20149	1927	0.347	0.6021	Yes
47	IL1B	14431	1961	0.336	0.6047	Yes
48	MAP2K3	20856	1975	0.333	0.6083	Yes
49	ARRB2	20806	1981	0.330	0.6124	Yes
50	JUN	15832	2037	0.313	0.6135	Yes
51	GNG12	4789	2082	0.298	0.6150	Yes
52	RAC1	16302	2149	0.281	0.6150	Yes
53	MAX	21034	2221	0.262	0.6146	No
54	EGF	15169	2310	0.241	0.6130	No
55	MAPK3	6458 11170	2440	0.214	0.6087	No
56	MAP3K4	23126	2446	0.212	0.6112	No
57	TRAF2	14657	2502	0.200	0.6109	No
58	RASA2	4329	2532	0.194	0.6118	No
59	CACNB2	4466 8678	2590	0.180	0.6111	No
60	MAP3K8	23495	2611	0.176	0.6123	No
61	RAP1B	10083	2625	0.172	0.6138	No
62	SRF	22961 1597	2654	0.165	0.6145	No
63	RPS6KA1	15725	2699	0.155	0.6141	No
64	FOS	21202	2816	0.135	0.6095	No
65	PAK1	9527	2858	0.127	0.6090	No
66	CD14	23452	2861	0.126	0.6105	No
67	ACVR1B	4335 22353	2930	0.114	0.6083	No
68	MAP3K7	16255	3003	0.105	0.6058	No
69	RAF1	17035	3038	0.101	0.6052	No
70	MYC	22465 9435	3120	0.093	0.6020	No
71	MAP2K1	19082	3174	0.087	0.6003	No
72	MAPK13	23314	3189	0.086	0.6007	No
73	NF1	5165	3219	0.082	0.6001	No
74	FGFR2	1917 4722 1119	3240	0.081	0.6001	No
75	PDGFRB	23539	3339	0.072	0.5957	No
76	RASGRP4	6119	3340	0.072	0.5967	No
77	MAPK8IP3	11402 23080	3458	0.062	0.5911	No
78	CDC25B	14841	3547	0.056	0.5870	No
79	MAP2K5	19088	3584	0.054	0.5858	No
80	GNA12	9023	3653	0.049	0.5827	No
81	DUSP7	10661	3679	0.048	0.5820	No
82	RASGRP1	5360 14476 9694	3767	0.043	0.5778	No
83	PDGFA	5237	3830	0.040	0.5750	No
84	MAP3K10	3831 17916	3932	0.036	0.5700	No
85	CASP3	8693	3967	0.034	0.5685	No
86	FAS	23881 3750	4136	0.028	0.5598	No
87	ARRB1	3890 8465 18178 4276	4151	0.028	0.5594	No
88	DUSP4	18632 3820	4155	0.028	0.5596	No
89	MAPK7	1381 20414	4301	0.024	0.5520	No
90	STK3	7084	4305	0.024	0.5522	No
91	FGF18	4721 1351	4370	0.022	0.5490	No
92	TNF	23004	4411	0.021	0.5471	No
93	DAXX	23290	4418	0.021	0.5470	No
94	CACNA1E	4465	4441	0.020	0.5461	No
95	MAP3K6	16054	4644	0.016	0.5353	No
96	SOS1	5476	4722	0.015	0.5313	No
97	ACVR1C	14585	4862	0.013	0.5239	No
98	CRK	4559 1249	4892	0.013	0.5225	No
99	CACNA1F	12054 24393	4942	0.013	0.5200	No
100	RAC3	20561	4987	0.012	0.5178	No
101	PLA2G2D	16018	5193	0.010	0.5068	No
102	CDC42	4503 8722 4504 2465	5208	0.010	0.5061	No
103	PPP3R1	9611 489	5297	0.010	0.5015	No
104	TGFBR1	16213 10165 5745	5364	0.009	0.4980	No
105	FGF4	8964	5376	0.009	0.4975	No
106	PPP3R2	9612	6019	0.006	0.4627	No
107	NR4A1	9099	6022	0.006	0.4626	No
108	MAP3K2	11165	6028	0.006	0.4624	No
109	DUSP9	24307	6164	0.005	0.4551	No
110	FGF21	17830	6170	0.005	0.4549	No
111	FGF1	1994 23447	6176	0.005	0.4547	No
112	DUSP16	1004 7699	6391	0.004	0.4431	No
113	CACNA1D	4464 8675	6392	0.004	0.4432	No
114	IL1R2	14265	6450	0.004	0.4402	No
115	PDGFB	22199 2311	6629	0.003	0.4305	No
116	PLA2G12B	20016	6687	0.003	0.4275	No
117	PLA2G1B	9581	6716	0.003	0.4260	No
118	FGF16	24270	6721	0.003	0.4258	No
119	CACNA1H	23077	7106	0.002	0.4049	No
120	PRKX	9619 5290	7254	0.002	0.3970	No
121	FASLG	13789	7673	0.001	0.3742	No
122	FGF7	8965	7875	0.000	0.3633	No
123	FGF14	21716 3005 3463	8086	-0.000	0.3519	No
124	FGF5	16785	8104	-0.000	0.3509	No
125	FGFR1	3789 8968	8129	-0.000	0.3496	No
126	NTF5	18248	8312	-0.001	0.3397	No
127	PLA2G3	20968	8330	-0.001	0.3388	No
128	CACNG3	12029	8441	-0.001	0.3329	No
129	RPS6KA2	9759 9758	8473	-0.001	0.3312	No
130	RPS6KA5	2076 21005	8560	-0.001	0.3265	No
131	MRAS	9409	8608	-0.001	0.3240	No
132	NTRK2	9491	8794	-0.002	0.3139	No
133	CACNG7	13497	8816	-0.002	0.3128	No
134	PLA2G5	9583	9022	-0.002	0.3017	No
135	CACNG6	7033	9161	-0.003	0.2942	No
136	MOS	16254	9303	-0.003	0.2866	No
137	CACNG5	1339 20175	9354	-0.003	0.2839	No
138	NFATC2	5168 2866	9388	-0.003	0.2822	No
139	MAPKAPK5	16387	9650	-0.004	0.2680	No
140	RPS6KA6	12458	9781	-0.004	0.2610	No
141	FGF8	23656	9836	-0.005	0.2581	No
142	TAOK2	10610 3794	9984	-0.005	0.2502	No
143	FGF12	1723 22621	9991	-0.005	0.2499	No
144	AKT2	4365 4366	10087	-0.005	0.2448	No
145	PLA2G2E	16016	10108	-0.005	0.2438	No
146	CACNG4	20176	10149	-0.005	0.2417	No
147	CACNG8	13498	10182	-0.006	0.2400	No
148	RAP1A	8467	10259	-0.006	0.2360	No
149	IKBKG	2570 2562 4908	10346	-0.006	0.2314	No
150	EVI1	4689 8926	10409	-0.006	0.2281	No
151	FGF11	20383	10692	-0.007	0.2128	No
152	FGF10	4719 8962	10747	-0.007	0.2100	No
153	CACNB3	22373 8679	10777	-0.007	0.2085	No
154	FLNC	4302 8510	11215	-0.009	0.1849	No
155	CACNA1A	4461	11243	-0.009	0.1835	No
156	PLA2G10	22658	11321	-0.009	0.1794	No
157	NFATC4	22002	11335	-0.009	0.1788	No
158	MAP2K7	6453	11501	-0.010	0.1700	No
159	PLA2G4A	13809	11620	-0.011	0.1637	No
160	PLA2G2A	16017	11629	-0.011	0.1634	No
161	PRKCA	20174	11674	-0.011	0.1612	No
162	BDNF	14926 2797	11684	-0.011	0.1608	No
163	FGF20	18892	11825	-0.012	0.1534	No
164	CACNA1B	8673 4462	11859	-0.012	0.1517	No
165	MAP3K13	22814	11915	-0.012	0.1489	No
166	PDGFRA	16824	11924	-0.012	0.1486	No
167	PRKACA	18549 3844	11943	-0.012	0.1478	No
168	FGFR3	8969 3566	12054	-0.013	0.1420	No
169	PTPRR	3436 19876	12101	-0.013	0.1396	No
170	IL1A	4915	12109	-0.013	0.1394	No
171	NTF3	16991	12165	-0.014	0.1366	No
172	FGF17	21757	12265	-0.014	0.1314	No
173	DUSP10	4003 14016	12461	-0.016	0.1210	No
174	FGF22	12468 7385	12479	-0.016	0.1203	No
175	PLA2G6	22209	12521	-0.016	0.1183	No
176	FGF9	8966	12523	-0.016	0.1185	No
177	EGFR	1329 20944	12610	-0.017	0.1140	No
178	CACNA1C	1158 1166 24464 4463 8674	12619	-0.017	0.1138	No
179	CACNB4	4467	12626	-0.017	0.1137	No
180	FGFR4	3226	12709	-0.018	0.1095	No
181	ELK4	8895 4664 3937	12836	-0.019	0.1029	No
182	MAPK8IP2	77	12876	-0.020	0.1010	No
183	FGF2	15608	13003	-0.021	0.0944	No
184	TGFBR2	2994 3001 10167	13012	-0.021	0.0943	No
185	NGFB	15476	13093	-0.022	0.0902	No
186	CACNA1G	1237 940 20292	13112	-0.022	0.0895	No
187	TGFB3	10161	13172	-0.023	0.0866	No
188	AKT1	8568	13176	-0.023	0.0867	No
189	IL1R1	14264 3987	13385	-0.026	0.0757	No
190	MAPK10	11169	13498	-0.027	0.0700	No
191	DUSP14	12124	13996	-0.036	0.0434	No
192	MAP2K1IP1	12158	13997	-0.036	0.0439	No
193	NTRK1	15299	14008	-0.037	0.0438	No
194	MAPK11	2264 9618 22163	14100	-0.039	0.0394	No
195	MAPT	9420 1347	14103	-0.039	0.0398	No
196	TNFRSF1A	1181 10206	14144	-0.040	0.0381	No
197	RASGRF1	3050 19357	14265	-0.043	0.0322	No
198	PLA2G2F	15700	14489	-0.050	0.0207	No
199	NLK	5179 5178	14530	-0.051	0.0192	No
200	FGF3	17997	14667	-0.058	0.0125	No
201	CACNG1	20177	14800	-0.064	0.0062	No
202	FGF23	17275	14821	-0.065	0.0060	No
203	DUSP3	1358 13022	14853	-0.067	0.0051	No
204	RASGRF2	21397	14857	-0.067	0.0059	No
205	RPS6KA3	8490	14937	-0.071	0.0025	No
206	DUSP8	9493	15055	-0.079	-0.0028	No
207	CACNA2D2	7154	15056	-0.079	-0.0018	No
208	MAP3K12	6454 11164	15194	-0.089	-0.0081	No
209	ATF2	4418 2759	15321	-0.100	-0.0137	No
210	CACNB1	1443 1304	15347	-0.103	-0.0137	No
211	MAP2K6	20614 1414	15369	-0.106	-0.0134	No
212	CACNA2D3	8677	15449	-0.114	-0.0162	No
213	MAP2K4	20405	15611	-0.134	-0.0233	No
214	MKNK1	2504	15624	-0.136	-0.0221	No
215	MAP2K2	19933	15726	-0.151	-0.0256	No
216	PTPN5	17817	15755	-0.154	-0.0252	No
217	GADD45G	21637	15775	-0.157	-0.0241	No
218	PAK2	10310 5875	16141	-0.223	-0.0411	No
219	PPP5C	17952	16156	-0.226	-0.0389	No
220	STMN1	9261	16175	-0.230	-0.0369	No
221	CACNA1S	14111	16179	-0.231	-0.0340	No
222	NRAS	5191	16222	-0.243	-0.0331	No
223	MAPK8	6459	16226	-0.245	-0.0301	No
224	IKBKB	4907	16287	-0.259	-0.0300	No
225	FLNA	24129	16355	-0.272	-0.0300	No
226	RASGRP3	10767	16399	-0.284	-0.0287	No
227	GADD45B	19935	16500	-0.310	-0.0301	No
228	HRAS	4868	16569	-0.329	-0.0295	No
229	FLNB	13742	16904	-0.436	-0.0419	No
230	MAPKAPK3	19003	16967	-0.461	-0.0393	No
231	MAPK12	2182 2215 22164	17159	-0.534	-0.0427	No
232	CHUK	23665	17214	-0.556	-0.0384	No
233	ATF4	22417 2239	17300	-0.600	-0.0352	No
234	TGFB2	5743	17912	-0.982	-0.0556	No
235	MAP4K1	18313	18009	-1.088	-0.0466	No
236	PPP3CA	1863 5284	18249	-1.415	-0.0411	No
237	ECSIT	11248	18302	-1.518	-0.0241	No
238	PLA2G12A	1782 7281 1839	18573	-3.146	0.0023	No