Details for gene set HSA00240_PYRIMIDINE

Table: GSEA Results Summary

Dataset	Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos
Phenotype	phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos
Upregulated in class	DMpreB
GeneSet	HSA00240_PYRIMIDINE_METABOLISM
Enrichment Score (ES)	-0.7156337
Normalized Enrichment Score (NES)	-1.6164587
Nominal p-value	0.0023148148
FDR q-value	0.05611973
FWER p-Value	0.205

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	NP	22027 9597 5273 5274	282	1.916	0.0213	No
2	RRM2	5401 5400	406	1.594	0.0451	No
3	DCK	16808	533	1.402	0.0650	No
4	UCK1	10254 5831 10253	810	0.983	0.0688	No
5	ZNRD1	1491 22987	1460	0.545	0.0442	No
6	POLD1	17847	1885	0.362	0.0282	No
7	POLD4	12822	2043	0.311	0.0257	No
8	POLD3	17742	2045	0.311	0.0316	No
9	NT5C2	3768 8052	2123	0.288	0.0329	No
10	TK2	18779	2130	0.286	0.0380	No
11	RRM1	18163	2272	0.249	0.0352	No
12	TK1	1457 10182 5762	2677	0.160	0.0164	No
13	TXNRD1	19923	3122	0.093	-0.0058	No
14	POLR1A	9749 5393	3151	0.090	-0.0055	No
15	UPP1	20947 1385	4071	0.030	-0.0545	No
16	CTPS2	12060 2571	4444	0.020	-0.0742	No
17	TYMS	5810 5809 3606 3598	4667	0.016	-0.0859	No
18	ITPA	9193	5277	0.010	-0.1185	No
19	POLR2C	9750	5939	0.006	-0.1541	No
20	POLA1	24112	6822	0.003	-0.2016	No
21	POLE2	21053	7971	0.000	-0.2635	No
22	DPYS	22305	8327	-0.001	-0.2826	No
23	POLR3K	12447 7372	8411	-0.001	-0.2871	No
24	ENTPD3	19266	8468	-0.001	-0.2901	No
25	NME7	926 4101 14070 3986 3946 931	9368	-0.003	-0.3385	No
26	CANT1	13304	9397	-0.003	-0.3400	No
27	ENTPD1	4495	9916	-0.005	-0.3678	No
28	POLR2B	16817	10051	-0.005	-0.3749	No
29	AICDA	17295 1087	10917	-0.008	-0.4214	No
30	DPYD	15437	11224	-0.009	-0.4378	No
31	ENTPD8	12996	11830	-0.012	-0.4702	No
32	UPB1	19988 3389	11898	-0.012	-0.4736	No
33	CDA	15702	12591	-0.017	-0.5106	No
34	RRM2B	6902 6903 11801	12681	-0.018	-0.5150	No
35	NT5C1B	21315	12821	-0.019	-0.5222	No
36	UPP2	15009 13346 8032	13099	-0.022	-0.5367	No
37	ENTPD6	4496 2678	13507	-0.028	-0.5581	No
38	ENTPD5	4497	14287	-0.043	-0.5993	No
39	NT5E	19360 18702	14695	-0.059	-0.6201	No
40	NUDT2	16239	15385	-0.109	-0.6552	No
41	PNPT1	20936	15580	-0.130	-0.6632	No
42	POLR2A	5394	15732	-0.152	-0.6685	No
43	ECGF1	22160	15899	-0.181	-0.6740	No
44	POLR2I	12839	15977	-0.195	-0.6744	No
45	POLE4	12441	16137	-0.223	-0.6787	No
46	POLR3A	21900	16773	-0.391	-0.7055	No
47	NT5C3	17136	16961	-0.457	-0.7069	Yes
48	PRIM1	19847	17124	-0.520	-0.7057	Yes
49	NME4	23065 1577	17137	-0.524	-0.6964	Yes
50	POLE	16755	17267	-0.584	-0.6922	Yes
51	POLA2	23988	17337	-0.614	-0.6842	Yes
52	ENTPD4	7449	17461	-0.675	-0.6780	Yes
53	UMPS	22606 1760	17470	-0.683	-0.6654	Yes
54	POLR2J	16672	17504	-0.698	-0.6539	Yes
55	POLE3	7200	17557	-0.740	-0.6426	Yes
56	TXNRD2	22829 1649	17575	-0.747	-0.6293	Yes
57	POLR2G	23753	17605	-0.763	-0.6163	Yes
58	NME6	3139 19297	17766	-0.890	-0.6080	Yes
59	NT5C	20151	17793	-0.910	-0.5920	Yes
60	NT5M	8345 4175	18008	-1.088	-0.5828	Yes
61	CAD	16886	18060	-1.150	-0.5637	Yes
62	DTYMK	5776	18170	-1.310	-0.5446	Yes
63	DHODH	7152	18225	-1.377	-0.5212	Yes
64	POLD2	20537	18251	-1.420	-0.4955	Yes
65	POLR2K	9413	18265	-1.440	-0.4688	Yes
66	NME1	9467	18295	-1.504	-0.4417	Yes
67	POLR2H	10888	18300	-1.513	-0.4130	Yes
68	POLR3H	13460 8135	18301	-1.515	-0.3842	Yes
69	POLR3B	12875	18347	-1.658	-0.3550	Yes
70	NME2	9468	18352	-1.671	-0.3234	Yes
71	RFC5	13005 7791	18353	-1.673	-0.2915	Yes
72	DCTD	18620	18471	-2.150	-0.2568	Yes
73	POLR1B	14857	18527	-2.516	-0.2118	Yes
74	CTPS	2514 15772	18542	-2.625	-0.1625	Yes
75	POLR2E	3325 19699	18562	-2.914	-0.1080	Yes
76	POLR1D	3593 3658 16623	18611	-5.818	0.0003	Yes