Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
Upregulated in class | DMpreB |
GeneSet | HSA00230_PURINE_METABOLISM |
Enrichment Score (ES) | -0.5849533 |
Normalized Enrichment Score (NES) | -1.4136422 |
Nominal p-value | 0.0066815144 |
FDR q-value | 0.3894714 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IMPDH1 | 17197 1131 | 10 | 5.254 | 0.0677 | No | ||
2 | GMPR | 21651 | 37 | 3.843 | 0.1161 | No | ||
3 | NP | 22027 9597 5273 5274 | 282 | 1.916 | 0.1278 | No | ||
4 | RRM2 | 5401 5400 | 406 | 1.594 | 0.1418 | No | ||
5 | DCK | 16808 | 533 | 1.402 | 0.1532 | No | ||
6 | PKM2 | 3642 9573 | 769 | 1.030 | 0.1539 | No | ||
7 | ADA | 2703 14361 | 903 | 0.904 | 0.1584 | No | ||
8 | HPRT1 | 2655 24339 408 | 1247 | 0.653 | 0.1484 | No | ||
9 | PDE2A | 18170 | 1343 | 0.601 | 0.1510 | No | ||
10 | ZNRD1 | 1491 22987 | 1460 | 0.545 | 0.1518 | No | ||
11 | AK2 | 8563 2479 16073 | 1538 | 0.507 | 0.1542 | No | ||
12 | PAPSS1 | 15419 | 1693 | 0.439 | 0.1516 | No | ||
13 | DGUOK | 17099 1041 | 1784 | 0.397 | 0.1519 | No | ||
14 | POLD1 | 17847 | 1885 | 0.362 | 0.1512 | No | ||
15 | POLD4 | 12822 | 2043 | 0.311 | 0.1467 | No | ||
16 | POLD3 | 17742 | 2045 | 0.311 | 0.1507 | No | ||
17 | XDH | 22897 | 2056 | 0.308 | 0.1541 | No | ||
18 | NT5C2 | 3768 8052 | 2123 | 0.288 | 0.1543 | No | ||
19 | PDE4B | 9543 | 2129 | 0.286 | 0.1578 | No | ||
20 | RRM1 | 18163 | 2272 | 0.249 | 0.1533 | No | ||
21 | ADCY9 | 22680 | 2387 | 0.225 | 0.1501 | No | ||
22 | PDE3B | 5236 | 2535 | 0.194 | 0.1446 | No | ||
23 | PDE5A | 15431 | 3112 | 0.094 | 0.1147 | No | ||
24 | POLR1A | 9749 5393 | 3151 | 0.090 | 0.1138 | No | ||
25 | GUCY1B3 | 15311 | 3255 | 0.079 | 0.1093 | No | ||
26 | ADCY6 | 22139 2283 8551 | 3694 | 0.047 | 0.0862 | No | ||
27 | PDE4C | 8481 | 3887 | 0.038 | 0.0763 | No | ||
28 | PDE4D | 10722 6235 | 4163 | 0.028 | 0.0618 | No | ||
29 | PDE6H | 17257 | 4231 | 0.026 | 0.0585 | No | ||
30 | AK1 | 4363 | 4331 | 0.023 | 0.0534 | No | ||
31 | NPR2 | 16230 | 4415 | 0.021 | 0.0492 | No | ||
32 | GDA | 4764 | 4583 | 0.017 | 0.0404 | No | ||
33 | GUCY1A3 | 7216 12245 15310 | 4587 | 0.017 | 0.0405 | No | ||
34 | ITPA | 9193 | 5277 | 0.010 | 0.0033 | No | ||
35 | POLR2C | 9750 | 5939 | 0.006 | -0.0324 | No | ||
36 | AMPD1 | 5051 | 6149 | 0.005 | -0.0436 | No | ||
37 | ADCY5 | 10312 | 6284 | 0.005 | -0.0508 | No | ||
38 | PDE11A | 10805 | 6291 | 0.005 | -0.0510 | No | ||
39 | PKLR | 1850 15545 | 6423 | 0.004 | -0.0581 | No | ||
40 | PDE6G | 20119 | 6543 | 0.004 | -0.0645 | No | ||
41 | POLA1 | 24112 | 6822 | 0.003 | -0.0795 | No | ||
42 | PAPSS2 | 6258 | 6981 | 0.002 | -0.0880 | No | ||
43 | ENPP3 | 19803 | 7572 | 0.001 | -0.1199 | No | ||
44 | GMPR2 | 2711 | 7601 | 0.001 | -0.1214 | No | ||
45 | POLE2 | 21053 | 7971 | 0.000 | -0.1413 | No | ||
46 | GUCY2F | 24045 | 8251 | -0.001 | -0.1564 | No | ||
47 | POLR3K | 12447 7372 | 8411 | -0.001 | -0.1650 | No | ||
48 | ENTPD3 | 19266 | 8468 | -0.001 | -0.1680 | No | ||
49 | PDE1C | 5235 | 8764 | -0.002 | -0.1840 | No | ||
50 | AK5 | 6042 | 8951 | -0.002 | -0.1940 | No | ||
51 | GUCY2C | 1140 16954 | 9096 | -0.003 | -0.2017 | No | ||
52 | ALLC | 21093 2130 | 9250 | -0.003 | -0.2100 | No | ||
53 | NME7 | 926 4101 14070 3986 3946 931 | 9368 | -0.003 | -0.2163 | No | ||
54 | CANT1 | 13304 | 9397 | -0.003 | -0.2177 | No | ||
55 | ADK | 3302 3454 8555 | 9439 | -0.003 | -0.2199 | No | ||
56 | ENTPD2 | 8713 | 9447 | -0.003 | -0.2202 | No | ||
57 | PDE1A | 9541 5234 | 9651 | -0.004 | -0.2312 | No | ||
58 | ADCY8 | 22281 | 9739 | -0.004 | -0.2358 | No | ||
59 | NPR1 | 9480 | 9833 | -0.005 | -0.2408 | No | ||
60 | ENTPD1 | 4495 | 9916 | -0.005 | -0.2452 | No | ||
61 | POLR2B | 16817 | 10051 | -0.005 | -0.2523 | No | ||
62 | AMPD3 | 4383 2110 | 10109 | -0.005 | -0.2554 | No | ||
63 | AMPD2 | 1931 15197 | 10186 | -0.006 | -0.2594 | No | ||
64 | PDE9A | 23301 | 10510 | -0.007 | -0.2768 | No | ||
65 | PDE7B | 19807 | 11234 | -0.009 | -0.3158 | No | ||
66 | GUCY1A2 | 19580 | 11336 | -0.009 | -0.3211 | No | ||
67 | ADCY4 | 2980 21818 | 11394 | -0.010 | -0.3241 | No | ||
68 | ENTPD8 | 12996 | 11830 | -0.012 | -0.3475 | No | ||
69 | PDE8A | 18202 | 12003 | -0.013 | -0.3566 | No | ||
70 | PDE8B | 5756 | 12097 | -0.013 | -0.3615 | No | ||
71 | RRM2B | 6902 6903 11801 | 12681 | -0.018 | -0.3928 | No | ||
72 | NT5C1B | 21315 | 12821 | -0.019 | -0.4000 | No | ||
73 | ADCY2 | 21412 | 13026 | -0.021 | -0.4108 | No | ||
74 | ENTPD6 | 4496 2678 | 13507 | -0.028 | -0.4364 | No | ||
75 | ENTPD5 | 4497 | 14287 | -0.043 | -0.4780 | No | ||
76 | AK3L1 | 8564 | 14368 | -0.046 | -0.4817 | No | ||
77 | PDE4A | 3037 19542 3083 3023 | 14574 | -0.054 | -0.4921 | No | ||
78 | ADCY3 | 21329 894 | 14613 | -0.055 | -0.4934 | No | ||
79 | NT5E | 19360 18702 | 14695 | -0.059 | -0.4970 | No | ||
80 | PDE10A | 23387 | 14716 | -0.060 | -0.4973 | No | ||
81 | NUDT2 | 16239 | 15385 | -0.109 | -0.5321 | No | ||
82 | PNPT1 | 20936 | 15580 | -0.130 | -0.5409 | No | ||
83 | POLR2A | 5394 | 15732 | -0.152 | -0.5471 | No | ||
84 | ENPP1 | 19804 | 15756 | -0.154 | -0.5463 | No | ||
85 | ECGF1 | 22160 | 15899 | -0.181 | -0.5516 | No | ||
86 | POLR2I | 12839 | 15977 | -0.195 | -0.5533 | No | ||
87 | POLE4 | 12441 | 16137 | -0.223 | -0.5590 | No | ||
88 | PDE7A | 9544 1788 | 16511 | -0.313 | -0.5751 | No | ||
89 | ADCY7 | 8552 448 | 16602 | -0.340 | -0.5755 | No | ||
90 | PAICS | 16820 | 16711 | -0.368 | -0.5766 | No | ||
91 | POLR3A | 21900 | 16773 | -0.391 | -0.5748 | No | ||
92 | NT5C3 | 17136 | 16961 | -0.457 | -0.5790 | Yes | ||
93 | PRPS2 | 24003 | 17003 | -0.473 | -0.5751 | Yes | ||
94 | PRIM1 | 19847 | 17124 | -0.520 | -0.5748 | Yes | ||
95 | NME4 | 23065 1577 | 17137 | -0.524 | -0.5687 | Yes | ||
96 | PRPS1 | 24233 | 17216 | -0.557 | -0.5657 | Yes | ||
97 | POLE | 16755 | 17267 | -0.584 | -0.5608 | Yes | ||
98 | POLA2 | 23988 | 17337 | -0.614 | -0.5566 | Yes | ||
99 | ENTPD4 | 7449 | 17461 | -0.675 | -0.5544 | Yes | ||
100 | POLR2J | 16672 | 17504 | -0.698 | -0.5477 | Yes | ||
101 | POLE3 | 7200 | 17557 | -0.740 | -0.5409 | Yes | ||
102 | POLR2G | 23753 | 17605 | -0.763 | -0.5335 | Yes | ||
103 | NUDT9 | 7897 | 17701 | -0.837 | -0.5278 | Yes | ||
104 | NME6 | 3139 19297 | 17766 | -0.890 | -0.5197 | Yes | ||
105 | GMPS | 15578 | 17789 | -0.909 | -0.5091 | Yes | ||
106 | NT5C | 20151 | 17793 | -0.910 | -0.4974 | Yes | ||
107 | IMPDH2 | 10730 | 17992 | -1.059 | -0.4944 | Yes | ||
108 | NT5M | 8345 4175 | 18008 | -1.088 | -0.4811 | Yes | ||
109 | ADSL | 4358 | 18020 | -1.099 | -0.4674 | Yes | ||
110 | FHIT | 21920 | 18144 | -1.263 | -0.4577 | Yes | ||
111 | NUDT5 | 15121 | 18200 | -1.351 | -0.4431 | Yes | ||
112 | POLD2 | 20537 | 18251 | -1.420 | -0.4274 | Yes | ||
113 | POLR2K | 9413 | 18265 | -1.440 | -0.4094 | Yes | ||
114 | NME1 | 9467 | 18295 | -1.504 | -0.3914 | Yes | ||
115 | POLR2H | 10888 | 18300 | -1.513 | -0.3720 | Yes | ||
116 | POLR3H | 13460 8135 | 18301 | -1.515 | -0.3523 | Yes | ||
117 | PPAT | 6081 | 18323 | -1.571 | -0.3331 | Yes | ||
118 | GUK1 | 20432 | 18334 | -1.590 | -0.3130 | Yes | ||
119 | PDE6D | 13897 3945 | 18338 | -1.612 | -0.2922 | Yes | ||
120 | POLR3B | 12875 | 18347 | -1.658 | -0.2711 | Yes | ||
121 | NME2 | 9468 | 18352 | -1.671 | -0.2497 | Yes | ||
122 | RFC5 | 13005 7791 | 18353 | -1.673 | -0.2280 | Yes | ||
123 | APRT | 8620 | 18381 | -1.754 | -0.2067 | Yes | ||
124 | ADSSL1 | 21136 2087 | 18391 | -1.789 | -0.1839 | Yes | ||
125 | GART | 22543 1754 | 18397 | -1.806 | -0.1608 | Yes | ||
126 | ATIC | 14231 3968 | 18439 | -2.032 | -0.1366 | Yes | ||
127 | POLR1B | 14857 | 18527 | -2.516 | -0.1086 | Yes | ||
128 | POLR2E | 3325 19699 | 18562 | -2.914 | -0.0727 | Yes | ||
129 | POLR1D | 3593 3658 16623 | 18611 | -5.818 | 0.0003 | Yes |