Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_04_transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB.phenotype_transDMproB_versus_DMpreB.cls #transDMproB_versus_DMpreB_repos |
| Phenotype | phenotype_transDMproB_versus_DMpreB.cls#transDMproB_versus_DMpreB_repos |
| Upregulated in class | DMpreB |
| GeneSet | DNA_REPLICATION_REACTOME |
| Enrichment Score (ES) | -0.74085486 |
| Normalized Enrichment Score (NES) | -1.5406272 |
| Nominal p-value | 0.012474013 |
| FDR q-value | 0.18123522 |
| FWER p-Value | 0.712 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MCM4 | 22655 1708 | 1406 | 0.569 | -0.0456 | No | ||
| 2 | POLD1 | 17847 | 1885 | 0.362 | -0.0523 | No | ||
| 3 | POLD4 | 12822 | 2043 | 0.311 | -0.0443 | No | ||
| 4 | POLD3 | 17742 | 2045 | 0.311 | -0.0279 | No | ||
| 5 | CDK2 | 3438 3373 19592 3322 | 2297 | 0.243 | -0.0286 | No | ||
| 6 | ORC2L | 385 13949 | 2903 | 0.119 | -0.0548 | No | ||
| 7 | RPS27A | 13433 | 4092 | 0.030 | -0.1172 | No | ||
| 8 | RFC1 | 16527 | 4684 | 0.016 | -0.1482 | No | ||
| 9 | ORC1L | 327 16144 | 6255 | 0.005 | -0.2325 | No | ||
| 10 | MCM6 | 4000 13845 4119 | 7088 | 0.002 | -0.2772 | No | ||
| 11 | POLE2 | 21053 | 7971 | 0.000 | -0.3246 | No | ||
| 12 | CDC45L | 22642 1752 | 9841 | -0.005 | -0.4250 | No | ||
| 13 | UBA52 | 10239 | 11368 | -0.010 | -0.5067 | No | ||
| 14 | CDC6 | 6221 6220 | 11380 | -0.010 | -0.5068 | No | ||
| 15 | CDC7 | 16765 3477 | 11666 | -0.011 | -0.5215 | No | ||
| 16 | UBC | 14 14 10241 15 16 | 12223 | -0.014 | -0.5507 | No | ||
| 17 | PRIM2A | 13986 | 12750 | -0.018 | -0.5781 | No | ||
| 18 | ORC4L | 11172 6460 | 14092 | -0.039 | -0.6482 | No | ||
| 19 | PCNA | 9535 | 15028 | -0.077 | -0.6945 | No | ||
| 20 | UBB | 10240 | 15457 | -0.115 | -0.7114 | No | ||
| 21 | RPA1 | 20349 | 15458 | -0.115 | -0.7053 | No | ||
| 22 | MCM5 | 18564 | 15898 | -0.181 | -0.7194 | No | ||
| 23 | RPA2 | 2330 16057 | 16209 | -0.239 | -0.7235 | No | ||
| 24 | ORC3L | 6941 | 16533 | -0.318 | -0.7240 | Yes | ||
| 25 | MCM2 | 17074 | 16760 | -0.388 | -0.7157 | Yes | ||
| 26 | PRIM1 | 19847 | 17124 | -0.520 | -0.7078 | Yes | ||
| 27 | CDT1 | 18437 | 17207 | -0.554 | -0.6830 | Yes | ||
| 28 | GMNN | 21513 | 17211 | -0.554 | -0.6538 | Yes | ||
| 29 | MCM10 | 14694 | 17246 | -0.575 | -0.6253 | Yes | ||
| 30 | POLE | 16755 | 17267 | -0.584 | -0.5955 | Yes | ||
| 31 | MCM3 | 13991 | 17291 | -0.596 | -0.5652 | Yes | ||
| 32 | POLA2 | 23988 | 17337 | -0.614 | -0.5352 | Yes | ||
| 33 | NACA | 9444 5147 | 17459 | -0.673 | -0.5062 | Yes | ||
| 34 | RPA3 | 12667 | 17600 | -0.761 | -0.4735 | Yes | ||
| 35 | ORC6L | 18539 | 17699 | -0.837 | -0.4345 | Yes | ||
| 36 | RFC3 | 12786 | 17717 | -0.850 | -0.3906 | Yes | ||
| 37 | RFC4 | 1735 22627 | 18026 | -1.106 | -0.3487 | Yes | ||
| 38 | ORC5L | 11173 3595 | 18152 | -1.276 | -0.2880 | Yes | ||
| 39 | POLD2 | 20537 | 18251 | -1.420 | -0.2182 | Yes | ||
| 40 | RFC5 | 13005 7791 | 18353 | -1.673 | -0.1353 | Yes | ||
| 41 | MCM7 | 9372 3568 | 18554 | -2.827 | 0.0033 | Yes |
